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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>468</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>92</PDBx:label_seq_id>
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>468</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>468</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>468</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_z>21.774</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>468</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>92</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>-4.139</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.184</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>468</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_y>-2.434</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.712</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>468</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="589">
         <PDBx:B_iso_or_equiv>28.41</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>-5.456</PDBx:Cartn_y>
         <PDBx:Cartn_z>16.072</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>93</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="590">
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         <PDBx:Cartn_y>-4.109</PDBx:Cartn_y>
         <PDBx:Cartn_z>16.039</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_z>15.828</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>470</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
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         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_seq_id>486</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>486</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>486</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>486</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>487</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>487</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>487</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>487</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>487</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>487</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>487</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>111</PDBx:label_seq_id>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>487</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>487</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>487</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_seq_id>491</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>O</PDBx:label_atom_id>
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         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>520</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>520</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>520</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>520</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>520</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>520</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>520</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>520</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:Cartn_z>12.090</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>521</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>11.129</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>521</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>521</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>521</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>521</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>521</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>OD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>521</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>OD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>521</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>525</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>149</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>525</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>149</PDBx:label_seq_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>525</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>149</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="1053">
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>525</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>149</PDBx:label_seq_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>525</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>5.609</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>525</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>149</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1056">
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         <PDBx:Cartn_y>17.846</PDBx:Cartn_y>
         <PDBx:Cartn_z>6.831</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>525</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>149</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_y>19.144</PDBx:Cartn_y>
         <PDBx:Cartn_z>6.888</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>525</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>149</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1058">
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         <PDBx:Cartn_y>19.924</PDBx:Cartn_y>
         <PDBx:Cartn_z>5.816</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>525</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>149</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1059">
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         <PDBx:Cartn_y>19.701</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.038</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>525</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>149</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1060">
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         <PDBx:Cartn_x>23.598</PDBx:Cartn_x>
         <PDBx:Cartn_y>15.503</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.178</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>526</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>150</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1061">
         <PDBx:B_iso_or_equiv>14.51</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>22.716</PDBx:Cartn_x>
         <PDBx:Cartn_y>14.628</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.982</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>526</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>150</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1062">
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         <PDBx:Cartn_x>21.345</PDBx:Cartn_x>
         <PDBx:Cartn_y>14.449</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.361</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>526</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>150</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1063">
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         <PDBx:Cartn_x>20.391</PDBx:Cartn_x>
         <PDBx:Cartn_y>14.141</PDBx:Cartn_y>
         <PDBx:Cartn_z>5.042</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>526</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>150</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="1064">
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         <PDBx:Cartn_y>15.115</PDBx:Cartn_y>
         <PDBx:Cartn_z>6.440</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>526</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>150</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1065">
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         <PDBx:Cartn_z>7.171</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>526</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>150</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1066">
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         <PDBx:Cartn_y>14.018</PDBx:Cartn_y>
         <PDBx:Cartn_z>6.894</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>544</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>168</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1196">
         <PDBx:B_iso_or_equiv>17.46</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>14.454</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.134</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>544</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>168</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1197">
         <PDBx:B_iso_or_equiv>20.66</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>14.196</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.370</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>544</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>168</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1198">
         <PDBx:B_iso_or_equiv>20.59</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>18.303</PDBx:Cartn_x>
         <PDBx:Cartn_y>13.320</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.374</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>544</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>168</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1199">
         <PDBx:B_iso_or_equiv>22.74</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>17.115</PDBx:Cartn_x>
         <PDBx:Cartn_y>12.726</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.475</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>544</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>168</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1200">
         <PDBx:B_iso_or_equiv>23.96</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.374</PDBx:Cartn_x>
         <PDBx:Cartn_y>12.890</PDBx:Cartn_y>
         <PDBx:Cartn_z>20.610</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>544</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>168</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1201">
         <PDBx:B_iso_or_equiv>23.60</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.706</PDBx:Cartn_x>
         <PDBx:Cartn_y>11.899</PDBx:Cartn_y>
         <PDBx:Cartn_z>18.507</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>544</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>168</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1202">
         <PDBx:B_iso_or_equiv>15.51</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>23.769</PDBx:Cartn_x>
         <PDBx:Cartn_y>11.113</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.411</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>169</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1203">
         <PDBx:B_iso_or_equiv>17.59</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>24.400</PDBx:Cartn_x>
         <PDBx:Cartn_y>9.859</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.887</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>169</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1204">
         <PDBx:B_iso_or_equiv>17.01</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>25.798</PDBx:Cartn_x>
         <PDBx:Cartn_y>9.749</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.411</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>169</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1205">
         <PDBx:B_iso_or_equiv>17.66</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>26.437</PDBx:Cartn_x>
         <PDBx:Cartn_y>8.690</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.612</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>169</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="1206">
         <PDBx:B_iso_or_equiv>18.65</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>23.540</PDBx:Cartn_x>
         <PDBx:Cartn_y>8.636</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.440</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>169</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1207">
         <PDBx:B_iso_or_equiv>16.31</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>22.107</PDBx:Cartn_x>
         <PDBx:Cartn_y>8.907</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.799</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>169</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1208">
         <PDBx:B_iso_or_equiv>19.31</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>21.723</PDBx:Cartn_x>
         <PDBx:Cartn_y>9.013</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.146</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>169</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1209">
         <PDBx:B_iso_or_equiv>17.58</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>21.128</PDBx:Cartn_x>
         <PDBx:Cartn_y>9.140</PDBx:Cartn_y>
         <PDBx:Cartn_z>18.799</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1210">
         <PDBx:B_iso_or_equiv>19.95</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>20.425</PDBx:Cartn_x>
         <PDBx:Cartn_y>9.406</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.511</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>545</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1211">
         <PDBx:B_iso_or_equiv>19.88</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>19.825</PDBx:Cartn_x>
         <PDBx:Cartn_y>9.540</PDBx:Cartn_y>
         <PDBx:Cartn_z>19.159</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_seq_id>561</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_seq_id>561</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>561</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CG1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG1</PDBx:label_atom_id>
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CG2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>562</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>562</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>562</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>562</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_z>5.503</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>562</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>186</PDBx:label_seq_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>27.273</PDBx:Cartn_y>
         <PDBx:Cartn_z>5.812</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>562</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_y>28.168</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.633</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>562</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_y>25.849</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.692</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>563</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>187</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1348">
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         <PDBx:Cartn_y>25.611</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.629</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>563</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>187</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1349">
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         <PDBx:Cartn_y>26.056</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.923</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>563</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>10.093</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>563</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>563</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>563</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>563</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>563</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>600</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>600</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:Cartn_z>-6.114</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>600</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>-4.305</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>600</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_y>31.771</PDBx:Cartn_y>
         <PDBx:Cartn_z>2.883</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>601</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>225</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1669">
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         <PDBx:Cartn_y>32.014</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.317</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>601</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>225</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1670">
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         <PDBx:Cartn_y>30.710</PDBx:Cartn_y>
         <PDBx:Cartn_z>5.074</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>601</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_z>4.679</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>601</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>225</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:Cartn_z>4.976</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>601</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>601</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>601</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>601</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
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         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_seq_id>615</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>239</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1776">
         <PDBx:B_iso_or_equiv>15.41</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>36.132</PDBx:Cartn_y>
         <PDBx:Cartn_z>3.436</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>615</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>239</PDBx:label_seq_id>
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      <PDBx:atom_site id="1777">
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         <PDBx:Cartn_y>36.857</PDBx:Cartn_y>
         <PDBx:Cartn_z>2.710</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>615</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>239</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="1778">
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         <PDBx:Cartn_y>36.810</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.640</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>615</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>239</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1779">
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         <PDBx:Cartn_y>37.284</PDBx:Cartn_y>
         <PDBx:Cartn_z>5.961</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>615</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>239</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1780">
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         <PDBx:Cartn_y>36.184</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.032</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>615</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>239</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1781">
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         <PDBx:Cartn_x>21.880</PDBx:Cartn_x>
         <PDBx:Cartn_y>36.559</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.280</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>615</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>239</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1782">
         <PDBx:B_iso_or_equiv>17.09</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>22.456</PDBx:Cartn_x>
         <PDBx:Cartn_y>36.987</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.397</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>615</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>239</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1783">
         <PDBx:B_iso_or_equiv>19.81</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>23.780</PDBx:Cartn_x>
         <PDBx:Cartn_y>37.198</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.458</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>615</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>239</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1784">
         <PDBx:B_iso_or_equiv>17.89</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>21.686</PDBx:Cartn_x>
         <PDBx:Cartn_y>37.166</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.496</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>615</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>239</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1785">
         <PDBx:B_iso_or_equiv>15.48</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>24.836</PDBx:Cartn_x>
         <PDBx:Cartn_y>34.906</PDBx:Cartn_y>
         <PDBx:Cartn_z>3.069</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>616</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>240</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1786">
         <PDBx:B_iso_or_equiv>14.92</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>25.238</PDBx:Cartn_x>
         <PDBx:Cartn_y>34.387</PDBx:Cartn_y>
         <PDBx:Cartn_z>1.764</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>616</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>240</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1787">
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         <PDBx:Cartn_x>24.610</PDBx:Cartn_x>
         <PDBx:Cartn_y>35.210</PDBx:Cartn_y>
         <PDBx:Cartn_z>0.635</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>616</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>240</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1788">
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         <PDBx:Cartn_x>23.462</PDBx:Cartn_x>
         <PDBx:Cartn_y>35.684</PDBx:Cartn_y>
         <PDBx:Cartn_z>0.744</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>616</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>240</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:Cartn_y>32.959</PDBx:Cartn_y>
         <PDBx:Cartn_z>1.639</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>616</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>240</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>31.984</PDBx:Cartn_y>
         <PDBx:Cartn_z>2.557</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>616</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>240</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1791">
         <PDBx:B_iso_or_equiv>14.99</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>24.640</PDBx:Cartn_x>
         <PDBx:Cartn_y>30.705</PDBx:Cartn_y>
         <PDBx:Cartn_z>2.804</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>616</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
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         <PDBx:label_atom_id>O</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
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         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
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         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
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         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
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         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>618</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>-8.613</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>618</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1814">
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         <PDBx:Cartn_z>-9.059</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>618</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1815">
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         <PDBx:Cartn_z>-9.325</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>618</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1816">
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         <PDBx:Cartn_y>32.969</PDBx:Cartn_y>
         <PDBx:Cartn_z>-5.183</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>619</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1817">
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         <PDBx:Cartn_y>32.164</PDBx:Cartn_y>
         <PDBx:Cartn_z>-6.287</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>619</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_z>-7.628</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>619</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>619</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>619</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>619</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
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         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>619</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>620</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>N</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
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         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>638</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>638</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>638</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>638</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:B_iso_or_equiv>20.44</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>12.986</PDBx:Cartn_x>
         <PDBx:Cartn_y>34.224</PDBx:Cartn_y>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>639</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:B_iso_or_equiv>22.86</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.556</PDBx:Cartn_x>
         <PDBx:Cartn_y>34.184</PDBx:Cartn_y>
         <PDBx:Cartn_z>16.435</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>639</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>263</PDBx:label_seq_id>
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      <PDBx:atom_site id="1977">
         <PDBx:B_iso_or_equiv>23.66</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.935</PDBx:Cartn_x>
         <PDBx:Cartn_y>34.876</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.203</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>639</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>263</PDBx:label_seq_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1978">
         <PDBx:B_iso_or_equiv>26.01</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.740</PDBx:Cartn_x>
         <PDBx:Cartn_y>34.784</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.990</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>639</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>639</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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      <PDBx:atom_site id="1980">
         <PDBx:B_iso_or_equiv>43.42</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>36.077</PDBx:Cartn_y>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>639</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:B_iso_or_equiv>47.60</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>36.866</PDBx:Cartn_y>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>639</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>OD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>OD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>640</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>640</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
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         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1985">
         <PDBx:B_iso_or_equiv>19.92</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.462</PDBx:Cartn_x>
         <PDBx:Cartn_y>35.320</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.976</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>640</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>264</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1986">
         <PDBx:B_iso_or_equiv>21.13</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.075</PDBx:Cartn_x>
         <PDBx:Cartn_y>35.693</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.857</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>640</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>264</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1987">
         <PDBx:B_iso_or_equiv>24.81</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>12.014</PDBx:Cartn_x>
         <PDBx:Cartn_y>37.559</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.973</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>640</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>264</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1988">
         <PDBx:B_iso_or_equiv>30.23</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.584</PDBx:Cartn_x>
         <PDBx:Cartn_y>38.601</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.000</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>640</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>264</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1989">
         <PDBx:B_iso_or_equiv>37.30</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.394</PDBx:Cartn_x>
         <PDBx:Cartn_y>39.336</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.519</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>640</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>264</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1990">
         <PDBx:B_iso_or_equiv>69.11</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.560</PDBx:Cartn_x>
         <PDBx:Cartn_y>40.484</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.058</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>640</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>264</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1991">
         <PDBx:B_iso_or_equiv>42.69</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.313</PDBx:Cartn_x>
         <PDBx:Cartn_y>38.767</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.594</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>640</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>264</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1992">
         <PDBx:B_iso_or_equiv>17.88</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>12.083</PDBx:Cartn_x>
         <PDBx:Cartn_y>34.165</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.161</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1993">
         <PDBx:B_iso_or_equiv>16.18</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>12.266</PDBx:Cartn_x>
         <PDBx:Cartn_y>33.252</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.032</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1994">
         <PDBx:B_iso_or_equiv>16.47</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.987</PDBx:Cartn_x>
         <PDBx:Cartn_y>32.459</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.829</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1995">
         <PDBx:B_iso_or_equiv>17.81</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.245</PDBx:Cartn_x>
         <PDBx:Cartn_y>32.238</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.788</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1996">
         <PDBx:B_iso_or_equiv>16.22</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>13.410</PDBx:Cartn_x>
         <PDBx:Cartn_y>32.233</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.355</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1997">
         <PDBx:B_iso_or_equiv>13.71</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.783</PDBx:Cartn_x>
         <PDBx:Cartn_y>32.932</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.523</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1998">
         <PDBx:B_iso_or_equiv>15.89</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.869</PDBx:Cartn_x>
         <PDBx:Cartn_y>31.908</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.960</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1999">
         <PDBx:B_iso_or_equiv>14.83</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.994</PDBx:Cartn_x>
         <PDBx:Cartn_y>32.692</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.486</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2000">
         <PDBx:B_iso_or_equiv>14.99</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>17.831</PDBx:Cartn_x>
         <PDBx:Cartn_y>32.255</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.467</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2001">
         <PDBx:B_iso_or_equiv>15.30</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>17.752</PDBx:Cartn_x>
         <PDBx:Cartn_y>30.985</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.897</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2002">
         <PDBx:B_iso_or_equiv>16.38</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>18.737</PDBx:Cartn_x>
         <PDBx:Cartn_y>33.114</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.026</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>641</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2003">
         <PDBx:B_iso_or_equiv>16.42</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.679</PDBx:Cartn_x>
         <PDBx:Cartn_y>32.088</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.574</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>642</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2004">
         <PDBx:B_iso_or_equiv>15.66</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.392</PDBx:Cartn_x>
         <PDBx:Cartn_y>31.384</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.321</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>642</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2005">
         <PDBx:B_iso_or_equiv>16.78</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.413</PDBx:Cartn_x>
         <PDBx:Cartn_y>29.978</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.916</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>642</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2006">
         <PDBx:B_iso_or_equiv>17.03</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.476</PDBx:Cartn_x>
         <PDBx:Cartn_y>29.508</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.380</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>642</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2007">
         <PDBx:B_iso_or_equiv>16.84</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.363</PDBx:Cartn_x>
         <PDBx:Cartn_y>31.322</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.759</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>642</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2008">
         <PDBx:B_iso_or_equiv>17.15</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.845</PDBx:Cartn_x>
         <PDBx:Cartn_y>31.306</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.389</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>642</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2009">
         <PDBx:B_iso_or_equiv>17.04</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.459</PDBx:Cartn_x>
         <PDBx:Cartn_y>32.314</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.351</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>642</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2010">
         <PDBx:B_iso_or_equiv>16.17</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.238</PDBx:Cartn_x>
         <PDBx:Cartn_y>29.331</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.929</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>643</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2011">
         <PDBx:B_iso_or_equiv>15.90</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.154</PDBx:Cartn_x>
         <PDBx:Cartn_y>27.923</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.203</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>643</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2012">
         <PDBx:B_iso_or_equiv>15.52</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.306</PDBx:Cartn_x>
         <PDBx:Cartn_y>27.150</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.850</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>643</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2013">
         <PDBx:B_iso_or_equiv>16.07</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.242</PDBx:Cartn_x>
         <PDBx:Cartn_y>27.726</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.750</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>643</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2014">
         <PDBx:B_iso_or_equiv>18.23</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>6.765</PDBx:Cartn_x>
         <PDBx:Cartn_y>27.563</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.723</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>643</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2015">
         <PDBx:B_iso_or_equiv>18.41</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>5.788</PDBx:Cartn_x>
         <PDBx:Cartn_y>27.938</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.705</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OG1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>643</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OG1</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2016">
         <PDBx:B_iso_or_equiv>19.17</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>6.505</PDBx:Cartn_x>
         <PDBx:Cartn_y>28.307</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.060</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>643</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG2</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>267</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2017">
         <PDBx:B_iso_or_equiv>16.35</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.500</PDBx:Cartn_x>
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         <PDBx:U12>0.0228</PDBx:U12>
         <PDBx:U13>0.0180</PDBx:U13>
         <PDBx:U22>0.1615</PDBx:U22>
         <PDBx:U23>-0.0132</PDBx:U23>
         <PDBx:U33>0.2462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="11">
         <PDBx:U11>0.3314</PDBx:U11>
         <PDBx:U12>0.0094</PDBx:U12>
         <PDBx:U13>0.0506</PDBx:U13>
         <PDBx:U22>0.1537</PDBx:U22>
         <PDBx:U23>0.0033</PDBx:U23>
         <PDBx:U33>0.2417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="12">
         <PDBx:U11>0.2851</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.2159</PDBx:U22>
         <PDBx:U23>-0.0261</PDBx:U23>
         <PDBx:U33>0.2601</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="13">
         <PDBx:U11>0.2590</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>0.0162</PDBx:U13>
         <PDBx:U22>0.1843</PDBx:U22>
         <PDBx:U23>-0.0187</PDBx:U23>
         <PDBx:U33>0.2557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="14">
         <PDBx:U11>0.3082</PDBx:U11>
         <PDBx:U12>0.0050</PDBx:U12>
         <PDBx:U13>0.0429</PDBx:U13>
         <PDBx:U22>0.1981</PDBx:U22>
         <PDBx:U23>0.0100</PDBx:U23>
         <PDBx:U33>0.2326</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="15">
         <PDBx:U11>0.3097</PDBx:U11>
         <PDBx:U12>0.0063</PDBx:U12>
         <PDBx:U13>0.0326</PDBx:U13>
         <PDBx:U22>0.2287</PDBx:U22>
         <PDBx:U23>0.0243</PDBx:U23>
         <PDBx:U33>0.3293</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="16">
         <PDBx:U11>0.3144</PDBx:U11>
         <PDBx:U12>0.0500</PDBx:U12>
         <PDBx:U13>0.0430</PDBx:U13>
         <PDBx:U22>0.2331</PDBx:U22>
         <PDBx:U23>-0.0161</PDBx:U23>
         <PDBx:U33>0.2933</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="17">
         <PDBx:U11>0.3380</PDBx:U11>
         <PDBx:U12>-0.0203</PDBx:U12>
         <PDBx:U13>0.0426</PDBx:U13>
         <PDBx:U22>0.2406</PDBx:U22>
         <PDBx:U23>-0.0016</PDBx:U23>
         <PDBx:U33>0.2667</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="18">
         <PDBx:U11>0.2711</PDBx:U11>
         <PDBx:U12>-0.0260</PDBx:U12>
         <PDBx:U13>0.0512</PDBx:U13>
         <PDBx:U22>0.1731</PDBx:U22>
         <PDBx:U23>-0.0218</PDBx:U23>
         <PDBx:U33>0.3076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="19">
         <PDBx:U11>0.1997</PDBx:U11>
         <PDBx:U12>-0.0586</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.1655</PDBx:U22>
         <PDBx:U23>0.0025</PDBx:U23>
         <PDBx:U33>0.2991</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="20">
         <PDBx:U11>0.2589</PDBx:U11>
         <PDBx:U12>-0.0145</PDBx:U12>
         <PDBx:U13>-0.0086</PDBx:U13>
         <PDBx:U22>0.2302</PDBx:U22>
         <PDBx:U23>0.0013</PDBx:U23>
         <PDBx:U33>0.2609</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="21">
         <PDBx:U11>0.2868</PDBx:U11>
         <PDBx:U12>0.0116</PDBx:U12>
         <PDBx:U13>-0.0063</PDBx:U13>
         <PDBx:U22>0.1845</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.2560</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="22">
         <PDBx:U11>0.2623</PDBx:U11>
         <PDBx:U12>-0.0564</PDBx:U12>
         <PDBx:U13>0.0275</PDBx:U13>
         <PDBx:U22>0.1425</PDBx:U22>
         <PDBx:U23>-0.0211</PDBx:U23>
         <PDBx:U33>0.3384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="23">
         <PDBx:U11>0.2922</PDBx:U11>
         <PDBx:U12>-0.0223</PDBx:U12>
         <PDBx:U13>0.0093</PDBx:U13>
         <PDBx:U22>0.1759</PDBx:U22>
         <PDBx:U23>-0.0358</PDBx:U23>
         <PDBx:U33>0.3164</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="24">
         <PDBx:U11>0.3962</PDBx:U11>
         <PDBx:U12>-0.0268</PDBx:U12>
         <PDBx:U13>0.0842</PDBx:U13>
         <PDBx:U22>0.2338</PDBx:U22>
         <PDBx:U23>-0.0061</PDBx:U23>
         <PDBx:U33>0.3841</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="25">
         <PDBx:U11>0.3013</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.2122</PDBx:U22>
         <PDBx:U23>-0.0223</PDBx:U23>
         <PDBx:U33>0.2717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="26">
         <PDBx:U11>0.2505</PDBx:U11>
         <PDBx:U12>0.0016</PDBx:U12>
         <PDBx:U13>-0.0040</PDBx:U13>
         <PDBx:U22>0.1913</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.2397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="27">
         <PDBx:U11>0.2287</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>-0.0065</PDBx:U13>
         <PDBx:U22>0.2069</PDBx:U22>
         <PDBx:U23>-0.0246</PDBx:U23>
         <PDBx:U33>0.2560</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="28">
         <PDBx:U11>0.1990</PDBx:U11>
         <PDBx:U12>0.0131</PDBx:U12>
         <PDBx:U13>-0.0129</PDBx:U13>
         <PDBx:U22>0.1816</PDBx:U22>
         <PDBx:U23>0.0121</PDBx:U23>
         <PDBx:U33>0.2354</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="29">
         <PDBx:U11>0.2238</PDBx:U11>
         <PDBx:U12>-0.0081</PDBx:U12>
         <PDBx:U13>-0.0165</PDBx:U13>
         <PDBx:U22>0.1999</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.2479</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="30">
         <PDBx:U11>0.2526</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>-0.0430</PDBx:U13>
         <PDBx:U22>0.2660</PDBx:U22>
         <PDBx:U23>-0.0173</PDBx:U23>
         <PDBx:U33>0.3194</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="31">
         <PDBx:U11>0.2606</PDBx:U11>
         <PDBx:U12>0.0272</PDBx:U12>
         <PDBx:U13>-0.0441</PDBx:U13>
         <PDBx:U22>0.3642</PDBx:U22>
         <PDBx:U23>0.0021</PDBx:U23>
         <PDBx:U33>0.3512</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="32">
         <PDBx:U11>0.2696</PDBx:U11>
         <PDBx:U12>0.0365</PDBx:U12>
         <PDBx:U13>-0.0182</PDBx:U13>
         <PDBx:U22>0.2229</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.2340</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="33">
         <PDBx:U11>0.2304</PDBx:U11>
         <PDBx:U12>-0.0027</PDBx:U12>
         <PDBx:U13>-0.0279</PDBx:U13>
         <PDBx:U22>0.1565</PDBx:U22>
         <PDBx:U23>-0.0173</PDBx:U23>
         <PDBx:U33>0.2220</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="34">
         <PDBx:U11>0.2210</PDBx:U11>
         <PDBx:U12>-0.0008</PDBx:U12>
         <PDBx:U13>-0.0023</PDBx:U13>
         <PDBx:U22>0.1421</PDBx:U22>
         <PDBx:U23>0.0005</PDBx:U23>
         <PDBx:U33>0.2060</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="35">
         <PDBx:U11>0.2014</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0075</PDBx:U13>
         <PDBx:U22>0.1635</PDBx:U22>
         <PDBx:U23>0.0145</PDBx:U23>
         <PDBx:U33>0.2182</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="36">
         <PDBx:U11>0.2454</PDBx:U11>
         <PDBx:U12>-0.0224</PDBx:U12>
         <PDBx:U13>0.0126</PDBx:U13>
         <PDBx:U22>0.1550</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.2390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="37">
         <PDBx:U11>0.2302</PDBx:U11>
         <PDBx:U12>-0.0086</PDBx:U12>
         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.1437</PDBx:U22>
         <PDBx:U23>0.0164</PDBx:U23>
         <PDBx:U33>0.2381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="38">
         <PDBx:U11>0.2434</PDBx:U11>
         <PDBx:U12>-0.0180</PDBx:U12>
         <PDBx:U13>-0.0251</PDBx:U13>
         <PDBx:U22>0.1994</PDBx:U22>
         <PDBx:U23>0.0187</PDBx:U23>
         <PDBx:U33>0.2257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="39">
         <PDBx:U11>0.2684</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>0.0047</PDBx:U13>
         <PDBx:U22>0.2540</PDBx:U22>
         <PDBx:U23>0.0975</PDBx:U23>
         <PDBx:U33>0.3133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="40">
         <PDBx:U11>0.3264</PDBx:U11>
         <PDBx:U12>0.0426</PDBx:U12>
         <PDBx:U13>-0.0574</PDBx:U13>
         <PDBx:U22>0.3420</PDBx:U22>
         <PDBx:U23>0.1403</PDBx:U23>
         <PDBx:U33>0.4088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="41">
         <PDBx:U11>0.4476</PDBx:U11>
         <PDBx:U12>0.0308</PDBx:U12>
         <PDBx:U13>-0.0555</PDBx:U13>
         <PDBx:U22>0.3637</PDBx:U22>
         <PDBx:U23>0.0033</PDBx:U23>
         <PDBx:U33>0.3202</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="42">
         <PDBx:U11>0.2240</PDBx:U11>
         <PDBx:U12>-0.0040</PDBx:U12>
         <PDBx:U13>-0.0040</PDBx:U13>
         <PDBx:U22>0.1281</PDBx:U22>
         <PDBx:U23>0.0410</PDBx:U23>
         <PDBx:U33>0.2252</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="43">
         <PDBx:U11>0.2042</PDBx:U11>
         <PDBx:U12>-0.0070</PDBx:U12>
         <PDBx:U13>-0.0068</PDBx:U13>
         <PDBx:U22>0.1599</PDBx:U22>
         <PDBx:U23>0.0299</PDBx:U23>
         <PDBx:U33>0.2433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="44">
         <PDBx:U11>0.2372</PDBx:U11>
         <PDBx:U12>-0.0261</PDBx:U12>
         <PDBx:U13>-0.0094</PDBx:U13>
         <PDBx:U22>0.1695</PDBx:U22>
         <PDBx:U23>0.0194</PDBx:U23>
         <PDBx:U33>0.2416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="45">
         <PDBx:U11>0.2711</PDBx:U11>
         <PDBx:U12>-0.0210</PDBx:U12>
         <PDBx:U13>-0.0227</PDBx:U13>
         <PDBx:U22>0.1830</PDBx:U22>
         <PDBx:U23>0.0171</PDBx:U23>
         <PDBx:U33>0.2701</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="46">
         <PDBx:U11>0.1921</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>-0.0042</PDBx:U13>
         <PDBx:U22>0.1909</PDBx:U22>
         <PDBx:U23>0.0185</PDBx:U23>
         <PDBx:U33>0.2717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="47">
         <PDBx:U11>0.2447</PDBx:U11>
         <PDBx:U12>-0.0265</PDBx:U12>
         <PDBx:U13>-0.0076</PDBx:U13>
         <PDBx:U22>0.1968</PDBx:U22>
         <PDBx:U23>0.0078</PDBx:U23>
         <PDBx:U33>0.2654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="48">
         <PDBx:U11>0.2538</PDBx:U11>
         <PDBx:U12>-0.0229</PDBx:U12>
         <PDBx:U13>0.0078</PDBx:U13>
         <PDBx:U22>0.1791</PDBx:U22>
         <PDBx:U23>0.0167</PDBx:U23>
         <PDBx:U33>0.2797</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="49">
         <PDBx:U11>0.3219</PDBx:U11>
         <PDBx:U12>-0.0127</PDBx:U12>
         <PDBx:U13>0.0472</PDBx:U13>
         <PDBx:U22>0.2883</PDBx:U22>
         <PDBx:U23>-0.0316</PDBx:U23>
         <PDBx:U33>0.3483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="50">
         <PDBx:U11>0.2354</PDBx:U11>
         <PDBx:U12>-0.0085</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.1652</PDBx:U22>
         <PDBx:U23>0.0027</PDBx:U23>
         <PDBx:U33>0.2191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="51">
         <PDBx:U11>0.2163</PDBx:U11>
         <PDBx:U12>-0.0297</PDBx:U12>
         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.2253</PDBx:U22>
         <PDBx:U23>0.0073</PDBx:U23>
         <PDBx:U33>0.2536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="52">
         <PDBx:U11>0.2402</PDBx:U11>
         <PDBx:U12>-0.0206</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.2265</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.2739</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="53">
         <PDBx:U11>0.2846</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>0.0293</PDBx:U13>
         <PDBx:U22>0.2222</PDBx:U22>
         <PDBx:U23>0.0338</PDBx:U23>
         <PDBx:U33>0.3489</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="54">
         <PDBx:U11>0.2466</PDBx:U11>
         <PDBx:U12>0.0029</PDBx:U12>
         <PDBx:U13>-0.0015</PDBx:U13>
         <PDBx:U22>0.1703</PDBx:U22>
         <PDBx:U23>-0.0101</PDBx:U23>
         <PDBx:U33>0.2672</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="55">
         <PDBx:U11>0.2399</PDBx:U11>
         <PDBx:U12>-0.0192</PDBx:U12>
         <PDBx:U13>-0.0053</PDBx:U13>
         <PDBx:U22>0.1717</PDBx:U22>
         <PDBx:U23>-0.0140</PDBx:U23>
         <PDBx:U33>0.2710</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="56">
         <PDBx:U11>0.2899</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>-0.0450</PDBx:U13>
         <PDBx:U22>0.2096</PDBx:U22>
         <PDBx:U23>-0.0238</PDBx:U23>
         <PDBx:U33>0.2601</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="57">
         <PDBx:U11>0.2892</PDBx:U11>
         <PDBx:U12>-0.0310</PDBx:U12>
         <PDBx:U13>-0.0362</PDBx:U13>
         <PDBx:U22>0.1972</PDBx:U22>
         <PDBx:U23>0.0206</PDBx:U23>
         <PDBx:U33>0.2750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="58">
         <PDBx:U11>0.2643</PDBx:U11>
         <PDBx:U12>-0.0159</PDBx:U12>
         <PDBx:U13>0.0078</PDBx:U13>
         <PDBx:U22>0.2160</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.2575</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="59">
         <PDBx:U11>0.2708</PDBx:U11>
         <PDBx:U12>0.0154</PDBx:U12>
         <PDBx:U13>0.0259</PDBx:U13>
         <PDBx:U22>0.2406</PDBx:U22>
         <PDBx:U23>0.0325</PDBx:U23>
         <PDBx:U33>0.3270</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="60">
         <PDBx:U11>0.2900</PDBx:U11>
         <PDBx:U12>0.0050</PDBx:U12>
         <PDBx:U13>0.0600</PDBx:U13>
         <PDBx:U22>0.2396</PDBx:U22>
         <PDBx:U23>0.0349</PDBx:U23>
         <PDBx:U33>0.2971</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="61">
         <PDBx:U11>0.3191</PDBx:U11>
         <PDBx:U12>0.0312</PDBx:U12>
         <PDBx:U13>-0.0141</PDBx:U13>
         <PDBx:U22>0.2754</PDBx:U22>
         <PDBx:U23>0.0534</PDBx:U23>
         <PDBx:U33>0.3975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="62">
         <PDBx:U11>0.3409</PDBx:U11>
         <PDBx:U12>-0.0157</PDBx:U12>
         <PDBx:U13>0.0202</PDBx:U13>
         <PDBx:U22>0.2631</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.3722</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="63">
         <PDBx:U11>0.5607</PDBx:U11>
         <PDBx:U12>0.1871</PDBx:U12>
         <PDBx:U13>0.0144</PDBx:U13>
         <PDBx:U22>0.5924</PDBx:U22>
         <PDBx:U23>0.0121</PDBx:U23>
         <PDBx:U33>0.4173</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="64">
         <PDBx:U11>0.3575</PDBx:U11>
         <PDBx:U12>-0.0518</PDBx:U12>
         <PDBx:U13>0.0902</PDBx:U13>
         <PDBx:U22>0.2983</PDBx:U22>
         <PDBx:U23>-0.0858</PDBx:U23>
         <PDBx:U33>0.3510</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="65">
         <PDBx:U11>0.3017</PDBx:U11>
         <PDBx:U12>0.0087</PDBx:U12>
         <PDBx:U13>0.0364</PDBx:U13>
         <PDBx:U22>0.2541</PDBx:U22>
         <PDBx:U23>-0.0211</PDBx:U23>
         <PDBx:U33>0.2967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="66">
         <PDBx:U11>0.2835</PDBx:U11>
         <PDBx:U12>0.0248</PDBx:U12>
         <PDBx:U13>0.0552</PDBx:U13>
         <PDBx:U22>0.2623</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.3496</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="67">
         <PDBx:U11>0.3780</PDBx:U11>
         <PDBx:U12>0.0852</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.2583</PDBx:U22>
         <PDBx:U23>-0.0077</PDBx:U23>
         <PDBx:U33>0.3058</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="68">
         <PDBx:U11>0.4048</PDBx:U11>
         <PDBx:U12>0.0469</PDBx:U12>
         <PDBx:U13>0.1096</PDBx:U13>
         <PDBx:U22>0.2512</PDBx:U22>
         <PDBx:U23>-0.0350</PDBx:U23>
         <PDBx:U33>0.3838</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="69">
         <PDBx:U11>0.3045</PDBx:U11>
         <PDBx:U12>-0.0025</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.3614</PDBx:U22>
         <PDBx:U23>-0.0414</PDBx:U23>
         <PDBx:U33>0.3645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="70">
         <PDBx:U11>0.4075</PDBx:U11>
         <PDBx:U12>-0.0717</PDBx:U12>
         <PDBx:U13>0.0161</PDBx:U13>
         <PDBx:U22>0.3116</PDBx:U22>
         <PDBx:U23>0.0155</PDBx:U23>
         <PDBx:U33>0.3327</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="71">
         <PDBx:U11>0.4474</PDBx:U11>
         <PDBx:U12>0.0656</PDBx:U12>
         <PDBx:U13>0.0332</PDBx:U13>
         <PDBx:U22>0.2986</PDBx:U22>
         <PDBx:U23>0.0080</PDBx:U23>
         <PDBx:U33>0.3637</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="72">
         <PDBx:U11>0.3635</PDBx:U11>
         <PDBx:U12>-0.0736</PDBx:U12>
         <PDBx:U13>-0.0532</PDBx:U13>
         <PDBx:U22>0.2615</PDBx:U22>
         <PDBx:U23>0.0211</PDBx:U23>
         <PDBx:U33>0.3367</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="73">
         <PDBx:U11>0.3780</PDBx:U11>
         <PDBx:U12>0.0378</PDBx:U12>
         <PDBx:U13>0.0447</PDBx:U13>
         <PDBx:U22>0.3890</PDBx:U22>
         <PDBx:U23>-0.0184</PDBx:U23>
         <PDBx:U33>0.3747</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="74">
         <PDBx:U11>0.4018</PDBx:U11>
         <PDBx:U12>-0.0527</PDBx:U12>
         <PDBx:U13>0.0130</PDBx:U13>
         <PDBx:U22>0.3100</PDBx:U22>
         <PDBx:U23>-0.0383</PDBx:U23>
         <PDBx:U33>0.4577</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="75">
         <PDBx:U11>0.4152</PDBx:U11>
         <PDBx:U12>0.0371</PDBx:U12>
         <PDBx:U13>-0.0510</PDBx:U13>
         <PDBx:U22>0.2999</PDBx:U22>
         <PDBx:U23>0.0244</PDBx:U23>
         <PDBx:U33>0.4433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="76">
         <PDBx:U11>0.3002</PDBx:U11>
         <PDBx:U12>-0.0436</PDBx:U12>
         <PDBx:U13>0.0239</PDBx:U13>
         <PDBx:U22>0.2532</PDBx:U22>
         <PDBx:U23>-0.0261</PDBx:U23>
         <PDBx:U33>0.2788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="77">
         <PDBx:U11>0.2987</PDBx:U11>
         <PDBx:U12>-0.0503</PDBx:U12>
         <PDBx:U13>0.0847</PDBx:U13>
         <PDBx:U22>0.2647</PDBx:U22>
         <PDBx:U23>-0.0570</PDBx:U23>
         <PDBx:U33>0.3087</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="78">
         <PDBx:U11>0.3100</PDBx:U11>
         <PDBx:U12>-0.0506</PDBx:U12>
         <PDBx:U13>0.0957</PDBx:U13>
         <PDBx:U22>0.2692</PDBx:U22>
         <PDBx:U23>-0.0590</PDBx:U23>
         <PDBx:U33>0.4093</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="79">
         <PDBx:U11>0.3465</PDBx:U11>
         <PDBx:U12>-0.0488</PDBx:U12>
         <PDBx:U13>0.1277</PDBx:U13>
         <PDBx:U22>0.3145</PDBx:U22>
         <PDBx:U23>-0.0315</PDBx:U23>
         <PDBx:U33>0.3747</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="80">
         <PDBx:U11>0.3864</PDBx:U11>
         <PDBx:U12>-0.0553</PDBx:U12>
         <PDBx:U13>0.0341</PDBx:U13>
         <PDBx:U22>0.2522</PDBx:U22>
         <PDBx:U23>-0.0612</PDBx:U23>
         <PDBx:U33>0.3133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="81">
         <PDBx:U11>0.3034</PDBx:U11>
         <PDBx:U12>0.0040</PDBx:U12>
         <PDBx:U13>0.0150</PDBx:U13>
         <PDBx:U22>0.2345</PDBx:U22>
         <PDBx:U23>-0.0345</PDBx:U23>
         <PDBx:U33>0.3463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="82">
         <PDBx:U11>0.3576</PDBx:U11>
         <PDBx:U12>0.0177</PDBx:U12>
         <PDBx:U13>-0.0138</PDBx:U13>
         <PDBx:U22>0.2828</PDBx:U22>
         <PDBx:U23>-0.0259</PDBx:U23>
         <PDBx:U33>0.3645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="83">
         <PDBx:U11>0.4321</PDBx:U11>
         <PDBx:U12>0.0395</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.2345</PDBx:U22>
         <PDBx:U23>-0.0202</PDBx:U23>
         <PDBx:U33>0.3731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="84">
         <PDBx:U11>0.2870</PDBx:U11>
         <PDBx:U12>-0.0539</PDBx:U12>
         <PDBx:U13>0.0400</PDBx:U13>
         <PDBx:U22>0.2573</PDBx:U22>
         <PDBx:U23>-0.0494</PDBx:U23>
         <PDBx:U33>0.3387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="85">
         <PDBx:U11>0.3720</PDBx:U11>
         <PDBx:U12>-0.0960</PDBx:U12>
         <PDBx:U13>0.0521</PDBx:U13>
         <PDBx:U22>0.2883</PDBx:U22>
         <PDBx:U23>-0.0462</PDBx:U23>
         <PDBx:U33>0.3080</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="86">
         <PDBx:U11>0.3490</PDBx:U11>
         <PDBx:U12>-0.0588</PDBx:U12>
         <PDBx:U13>0.0796</PDBx:U13>
         <PDBx:U22>0.2467</PDBx:U22>
         <PDBx:U23>-0.0703</PDBx:U23>
         <PDBx:U33>0.3420</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="87">
         <PDBx:U11>0.3186</PDBx:U11>
         <PDBx:U12>-0.0408</PDBx:U12>
         <PDBx:U13>0.0646</PDBx:U13>
         <PDBx:U22>0.3442</PDBx:U22>
         <PDBx:U23>-0.0871</PDBx:U23>
         <PDBx:U33>0.3549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="88">
         <PDBx:U11>0.4785</PDBx:U11>
         <PDBx:U12>-0.0684</PDBx:U12>
         <PDBx:U13>0.0170</PDBx:U13>
         <PDBx:U22>0.3034</PDBx:U22>
         <PDBx:U23>-0.0403</PDBx:U23>
         <PDBx:U33>0.3233</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="89">
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         <PDBx:U12>-0.0484</PDBx:U12>
         <PDBx:U13>-0.0935</PDBx:U13>
         <PDBx:U22>0.4629</PDBx:U22>
         <PDBx:U23>-0.0279</PDBx:U23>
         <PDBx:U33>0.3168</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="90">
         <PDBx:U11>1.0064</PDBx:U11>
         <PDBx:U12>-0.0114</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.6381</PDBx:U22>
         <PDBx:U23>0.0589</PDBx:U23>
         <PDBx:U33>0.3009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="91">
         <PDBx:U11>1.0270</PDBx:U11>
         <PDBx:U12>-0.2367</PDBx:U12>
         <PDBx:U13>-0.2795</PDBx:U13>
         <PDBx:U22>0.7763</PDBx:U22>
         <PDBx:U23>-0.0607</PDBx:U23>
         <PDBx:U33>0.5609</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0297</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="100">
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="101">
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         <PDBx:U23>-0.0729</PDBx:U23>
         <PDBx:U33>0.5569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="102">
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         <PDBx:U22>0.2275</PDBx:U22>
         <PDBx:U23>-0.0136</PDBx:U23>
         <PDBx:U33>0.2465</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>0.0377</PDBx:U13>
         <PDBx:U22>0.2224</PDBx:U22>
         <PDBx:U23>0.0045</PDBx:U23>
         <PDBx:U33>0.2344</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="104">
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         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.2719</PDBx:U22>
         <PDBx:U23>0.0257</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.2627</PDBx:U22>
         <PDBx:U23>0.0716</PDBx:U23>
         <PDBx:U33>0.3612</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0286</PDBx:U23>
         <PDBx:U33>0.2184</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="107">
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         <PDBx:U22>0.1989</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.2241</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0091</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="125">
         <PDBx:U11>0.2672</PDBx:U11>
         <PDBx:U12>-0.0241</PDBx:U12>
         <PDBx:U13>0.0263</PDBx:U13>
         <PDBx:U22>0.1981</PDBx:U22>
         <PDBx:U23>-0.0223</PDBx:U23>
         <PDBx:U33>0.2043</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="126">
         <PDBx:U11>0.2461</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.1984</PDBx:U22>
         <PDBx:U23>0.0020</PDBx:U23>
         <PDBx:U33>0.2175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="127">
         <PDBx:U11>0.2572</PDBx:U11>
         <PDBx:U12>-0.0249</PDBx:U12>
         <PDBx:U13>-0.0197</PDBx:U13>
         <PDBx:U22>0.2294</PDBx:U22>
         <PDBx:U23>0.0067</PDBx:U23>
         <PDBx:U33>0.2083</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="128">
         <PDBx:U11>0.2858</PDBx:U11>
         <PDBx:U12>-0.0250</PDBx:U12>
         <PDBx:U13>-0.0536</PDBx:U13>
         <PDBx:U22>0.2204</PDBx:U22>
         <PDBx:U23>0.0128</PDBx:U23>
         <PDBx:U33>0.2546</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="129">
         <PDBx:U11>0.3313</PDBx:U11>
         <PDBx:U12>0.0285</PDBx:U12>
         <PDBx:U13>-0.0089</PDBx:U13>
         <PDBx:U22>0.2239</PDBx:U22>
         <PDBx:U23>0.0004</PDBx:U23>
         <PDBx:U33>0.2027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="130">
         <PDBx:U11>0.2946</PDBx:U11>
         <PDBx:U12>-0.0485</PDBx:U12>
         <PDBx:U13>0.0082</PDBx:U13>
         <PDBx:U22>0.2658</PDBx:U22>
         <PDBx:U23>-0.0308</PDBx:U23>
         <PDBx:U33>0.2242</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="131">
         <PDBx:U11>0.3330</PDBx:U11>
         <PDBx:U12>-0.0484</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.2224</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.2539</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="132">
         <PDBx:U11>0.3322</PDBx:U11>
         <PDBx:U12>-0.0461</PDBx:U12>
         <PDBx:U13>0.0200</PDBx:U13>
         <PDBx:U22>0.2629</PDBx:U22>
         <PDBx:U23>0.0241</PDBx:U23>
         <PDBx:U33>0.2499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="133">
         <PDBx:U11>0.2791</PDBx:U11>
         <PDBx:U12>-0.0054</PDBx:U12>
         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.2782</PDBx:U22>
         <PDBx:U23>0.0104</PDBx:U23>
         <PDBx:U33>0.2979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="134">
         <PDBx:U11>0.2604</PDBx:U11>
         <PDBx:U12>-0.0231</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1848</PDBx:U22>
         <PDBx:U23>0.0111</PDBx:U23>
         <PDBx:U33>0.2177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="135">
         <PDBx:U11>0.2378</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.1805</PDBx:U22>
         <PDBx:U23>0.0117</PDBx:U23>
         <PDBx:U33>0.2125</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="136">
         <PDBx:U11>0.2718</PDBx:U11>
         <PDBx:U12>-0.0126</PDBx:U12>
         <PDBx:U13>-0.0063</PDBx:U13>
         <PDBx:U22>0.2030</PDBx:U22>
         <PDBx:U23>-0.0057</PDBx:U23>
         <PDBx:U33>0.2136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="137">
         <PDBx:U11>0.2884</PDBx:U11>
         <PDBx:U12>0.0240</PDBx:U12>
         <PDBx:U13>0.0110</PDBx:U13>
         <PDBx:U22>0.1942</PDBx:U22>
         <PDBx:U23>0.0054</PDBx:U23>
         <PDBx:U33>0.2234</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="138">
         <PDBx:U11>0.2413</PDBx:U11>
         <PDBx:U12>-0.0259</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.1788</PDBx:U22>
         <PDBx:U23>0.0040</PDBx:U23>
         <PDBx:U33>0.2175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="139">
         <PDBx:U11>0.2626</PDBx:U11>
         <PDBx:U12>0.0040</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.2572</PDBx:U22>
         <PDBx:U23>-0.0176</PDBx:U23>
         <PDBx:U33>0.1774</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="140">
         <PDBx:U11>0.2828</PDBx:U11>
         <PDBx:U12>0.0019</PDBx:U12>
         <PDBx:U13>-0.0063</PDBx:U13>
         <PDBx:U22>0.1951</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.2191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="141">
         <PDBx:U11>0.2789</PDBx:U11>
         <PDBx:U12>-0.0122</PDBx:U12>
         <PDBx:U13>-0.0318</PDBx:U13>
         <PDBx:U22>0.2342</PDBx:U22>
         <PDBx:U23>-0.0426</PDBx:U23>
         <PDBx:U33>0.2139</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="142">
         <PDBx:U11>0.2574</PDBx:U11>
         <PDBx:U12>-0.0178</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.2044</PDBx:U22>
         <PDBx:U23>-0.0138</PDBx:U23>
         <PDBx:U33>0.2212</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="143">
         <PDBx:U11>0.2440</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>-0.0049</PDBx:U13>
         <PDBx:U22>0.2511</PDBx:U22>
         <PDBx:U23>-0.0288</PDBx:U23>
         <PDBx:U33>0.2463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="144">
         <PDBx:U11>0.2784</PDBx:U11>
         <PDBx:U12>-0.0312</PDBx:U12>
         <PDBx:U13>-0.0148</PDBx:U13>
         <PDBx:U22>0.2332</PDBx:U22>
         <PDBx:U23>0.0382</PDBx:U23>
         <PDBx:U33>0.2180</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="145">
         <PDBx:U11>0.2223</PDBx:U11>
         <PDBx:U12>0.0096</PDBx:U12>
         <PDBx:U13>-0.0115</PDBx:U13>
         <PDBx:U22>0.2401</PDBx:U22>
         <PDBx:U23>-0.0186</PDBx:U23>
         <PDBx:U33>0.2181</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="146">
         <PDBx:U11>0.2473</PDBx:U11>
         <PDBx:U12>0.0174</PDBx:U12>
         <PDBx:U13>-0.0204</PDBx:U13>
         <PDBx:U22>0.2150</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.1979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="147">
         <PDBx:U11>0.2254</PDBx:U11>
         <PDBx:U12>-0.0125</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.2128</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.2159</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="148">
         <PDBx:U11>0.2138</PDBx:U11>
         <PDBx:U12>-0.0072</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.2103</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.2494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="149">
         <PDBx:U11>0.2335</PDBx:U11>
         <PDBx:U12>-0.0111</PDBx:U12>
         <PDBx:U13>-0.0141</PDBx:U13>
         <PDBx:U22>0.2186</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.2368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="150">
         <PDBx:U11>0.2495</PDBx:U11>
         <PDBx:U12>0.0113</PDBx:U12>
         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.2234</PDBx:U22>
         <PDBx:U23>-0.0125</PDBx:U23>
         <PDBx:U33>0.2229</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="151">
         <PDBx:U11>0.2552</PDBx:U11>
         <PDBx:U12>0.0367</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.2317</PDBx:U22>
         <PDBx:U23>0.0264</PDBx:U23>
         <PDBx:U33>0.2200</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="152">
         <PDBx:U11>0.2429</PDBx:U11>
         <PDBx:U12>-0.0220</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.2423</PDBx:U22>
         <PDBx:U23>-0.0219</PDBx:U23>
         <PDBx:U33>0.2298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="153">
         <PDBx:U11>0.2900</PDBx:U11>
         <PDBx:U12>0.0672</PDBx:U12>
         <PDBx:U13>-0.0196</PDBx:U13>
         <PDBx:U22>0.2750</PDBx:U22>
         <PDBx:U23>-0.0846</PDBx:U23>
         <PDBx:U33>0.3402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="154">
         <PDBx:U11>0.3874</PDBx:U11>
         <PDBx:U12>0.0404</PDBx:U12>
         <PDBx:U13>-0.0831</PDBx:U13>
         <PDBx:U22>0.3385</PDBx:U22>
         <PDBx:U23>-0.1041</PDBx:U23>
         <PDBx:U33>0.4183</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="155">
         <PDBx:U11>0.3145</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>-0.0044</PDBx:U13>
         <PDBx:U22>0.3041</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.3357</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="156">
         <PDBx:U11>0.2407</PDBx:U11>
         <PDBx:U12>0.0046</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.2212</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.1957</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="157">
         <PDBx:U11>0.2529</PDBx:U11>
         <PDBx:U12>0.0185</PDBx:U12>
         <PDBx:U13>-0.0161</PDBx:U13>
         <PDBx:U22>0.2066</PDBx:U22>
         <PDBx:U23>-0.0207</PDBx:U23>
         <PDBx:U33>0.1898</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="158">
         <PDBx:U11>0.2001</PDBx:U11>
         <PDBx:U12>0.0133</PDBx:U12>
         <PDBx:U13>0.0355</PDBx:U13>
         <PDBx:U22>0.1745</PDBx:U22>
         <PDBx:U23>-0.0155</PDBx:U23>
         <PDBx:U33>0.2276</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="159">
         <PDBx:U11>0.2630</PDBx:U11>
         <PDBx:U12>-0.0128</PDBx:U12>
         <PDBx:U13>0.0316</PDBx:U13>
         <PDBx:U22>0.1989</PDBx:U22>
         <PDBx:U23>-0.0192</PDBx:U23>
         <PDBx:U33>0.2092</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="160">
         <PDBx:U11>0.2043</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>0.0249</PDBx:U13>
         <PDBx:U22>0.1817</PDBx:U22>
         <PDBx:U23>-0.0243</PDBx:U23>
         <PDBx:U33>0.2076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="161">
         <PDBx:U11>0.2090</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.1655</PDBx:U22>
         <PDBx:U23>0.0109</PDBx:U23>
         <PDBx:U33>0.2320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="162">
         <PDBx:U11>0.2942</PDBx:U11>
         <PDBx:U12>0.0119</PDBx:U12>
         <PDBx:U13>0.0085</PDBx:U13>
         <PDBx:U22>0.1910</PDBx:U22>
         <PDBx:U23>-0.0137</PDBx:U23>
         <PDBx:U33>0.2148</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="163">
         <PDBx:U11>0.2238</PDBx:U11>
         <PDBx:U12>-0.0091</PDBx:U12>
         <PDBx:U13>-0.0039</PDBx:U13>
         <PDBx:U22>0.1818</PDBx:U22>
         <PDBx:U23>-0.0425</PDBx:U23>
         <PDBx:U33>0.2311</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="164">
         <PDBx:U11>0.2659</PDBx:U11>
         <PDBx:U12>-0.0176</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.1892</PDBx:U22>
         <PDBx:U23>-0.0176</PDBx:U23>
         <PDBx:U33>0.2224</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="165">
         <PDBx:U11>0.2382</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>0.0277</PDBx:U13>
         <PDBx:U22>0.1935</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.2304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="166">
         <PDBx:U11>0.2643</PDBx:U11>
         <PDBx:U12>0.0006</PDBx:U12>
         <PDBx:U13>0.0326</PDBx:U13>
         <PDBx:U22>0.2243</PDBx:U22>
         <PDBx:U23>-0.0151</PDBx:U23>
         <PDBx:U33>0.2175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="167">
         <PDBx:U11>0.3512</PDBx:U11>
         <PDBx:U12>0.0487</PDBx:U12>
         <PDBx:U13>0.0223</PDBx:U13>
         <PDBx:U22>0.2282</PDBx:U22>
         <PDBx:U23>0.0049</PDBx:U23>
         <PDBx:U33>0.2642</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="168">
         <PDBx:U11>0.4049</PDBx:U11>
         <PDBx:U12>-0.0004</PDBx:U12>
         <PDBx:U13>-0.1064</PDBx:U13>
         <PDBx:U22>0.2639</PDBx:U22>
         <PDBx:U23>-0.0222</PDBx:U23>
         <PDBx:U33>0.4263</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="169">
         <PDBx:U11>0.3407</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>0.0565</PDBx:U13>
         <PDBx:U22>0.4771</PDBx:U22>
         <PDBx:U23>-0.0324</PDBx:U23>
         <PDBx:U33>0.3898</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="170">
         <PDBx:U11>0.4220</PDBx:U11>
         <PDBx:U12>0.0292</PDBx:U12>
         <PDBx:U13>-0.0257</PDBx:U13>
         <PDBx:U22>0.3399</PDBx:U22>
         <PDBx:U23>-0.0148</PDBx:U23>
         <PDBx:U33>0.3782</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="171">
         <PDBx:U11>0.4514</PDBx:U11>
         <PDBx:U12>0.0944</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.5030</PDBx:U22>
         <PDBx:U23>-0.1025</PDBx:U23>
         <PDBx:U33>0.4217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="172">
         <PDBx:U11>0.2576</PDBx:U11>
         <PDBx:U12>-0.0353</PDBx:U12>
         <PDBx:U13>0.0307</PDBx:U13>
         <PDBx:U22>0.2071</PDBx:U22>
         <PDBx:U23>0.0086</PDBx:U23>
         <PDBx:U33>0.2265</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="173">
         <PDBx:U11>0.2685</PDBx:U11>
         <PDBx:U12>-0.0543</PDBx:U12>
         <PDBx:U13>0.0311</PDBx:U13>
         <PDBx:U22>0.1880</PDBx:U22>
         <PDBx:U23>0.0163</PDBx:U23>
         <PDBx:U33>0.2058</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="174">
         <PDBx:U11>0.2503</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>0.0428</PDBx:U13>
         <PDBx:U22>0.1764</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.2357</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="175">
         <PDBx:U11>0.2429</PDBx:U11>
         <PDBx:U12>-0.0184</PDBx:U12>
         <PDBx:U13>0.0141</PDBx:U13>
         <PDBx:U22>0.2044</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.2681</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="176">
         <PDBx:U11>0.2981</PDBx:U11>
         <PDBx:U12>-0.0689</PDBx:U12>
         <PDBx:U13>0.0293</PDBx:U13>
         <PDBx:U22>0.2302</PDBx:U22>
         <PDBx:U23>0.0115</PDBx:U23>
         <PDBx:U33>0.2019</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="177">
         <PDBx:U11>0.3036</PDBx:U11>
         <PDBx:U12>-0.0498</PDBx:U12>
         <PDBx:U13>0.0198</PDBx:U13>
         <PDBx:U22>0.1815</PDBx:U22>
         <PDBx:U23>-0.0090</PDBx:U23>
         <PDBx:U33>0.2541</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="178">
         <PDBx:U11>0.2947</PDBx:U11>
         <PDBx:U12>-0.0220</PDBx:U12>
         <PDBx:U13>-0.0178</PDBx:U13>
         <PDBx:U22>0.2407</PDBx:U22>
         <PDBx:U23>0.0243</PDBx:U23>
         <PDBx:U33>0.2159</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="179">
         <PDBx:U11>0.3346</PDBx:U11>
         <PDBx:U12>0.0204</PDBx:U12>
         <PDBx:U13>0.0265</PDBx:U13>
         <PDBx:U22>0.2159</PDBx:U22>
         <PDBx:U23>-0.0150</PDBx:U23>
         <PDBx:U33>0.2952</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="180">
         <PDBx:U11>0.3601</PDBx:U11>
         <PDBx:U12>-0.0194</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.1895</PDBx:U22>
         <PDBx:U23>-0.0105</PDBx:U23>
         <PDBx:U33>0.2349</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="181">
         <PDBx:U11>0.3840</PDBx:U11>
         <PDBx:U12>0.0011</PDBx:U12>
         <PDBx:U13>-0.0486</PDBx:U13>
         <PDBx:U22>0.2794</PDBx:U22>
         <PDBx:U23>-0.0198</PDBx:U23>
         <PDBx:U33>0.3413</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="182">
         <PDBx:U11>0.3938</PDBx:U11>
         <PDBx:U12>-0.0240</PDBx:U12>
         <PDBx:U13>-0.0222</PDBx:U13>
         <PDBx:U22>0.2585</PDBx:U22>
         <PDBx:U23>-0.0702</PDBx:U23>
         <PDBx:U33>0.2954</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="183">
         <PDBx:U11>0.4299</PDBx:U11>
         <PDBx:U12>-0.0382</PDBx:U12>
         <PDBx:U13>-0.0663</PDBx:U13>
         <PDBx:U22>0.3337</PDBx:U22>
         <PDBx:U23>-0.0766</PDBx:U23>
         <PDBx:U33>0.3176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="184">
         <PDBx:U11>0.2694</PDBx:U11>
         <PDBx:U12>-0.0440</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.1620</PDBx:U22>
         <PDBx:U23>-0.0121</PDBx:U23>
         <PDBx:U33>0.2234</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="185">
         <PDBx:U11>0.3114</PDBx:U11>
         <PDBx:U12>-0.0468</PDBx:U12>
         <PDBx:U13>0.0036</PDBx:U13>
         <PDBx:U22>0.1652</PDBx:U22>
         <PDBx:U23>-0.0071</PDBx:U23>
         <PDBx:U33>0.3516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="186">
         <PDBx:U11>0.2823</PDBx:U11>
         <PDBx:U12>-0.0219</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.1770</PDBx:U22>
         <PDBx:U23>-0.0343</PDBx:U23>
         <PDBx:U33>0.2164</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="187">
         <PDBx:U11>0.2867</PDBx:U11>
         <PDBx:U12>-0.0324</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.1972</PDBx:U22>
         <PDBx:U23>0.0181</PDBx:U23>
         <PDBx:U33>0.2519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="188">
         <PDBx:U11>0.2662</PDBx:U11>
         <PDBx:U12>-0.0114</PDBx:U12>
         <PDBx:U13>0.0277</PDBx:U13>
         <PDBx:U22>0.1643</PDBx:U22>
         <PDBx:U23>-0.0334</PDBx:U23>
         <PDBx:U33>0.2640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="189">
         <PDBx:U11>0.2593</PDBx:U11>
         <PDBx:U12>-0.0097</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.1855</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.2509</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="190">
         <PDBx:U11>0.2512</PDBx:U11>
         <PDBx:U12>-0.0030</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.2020</PDBx:U22>
         <PDBx:U23>0.0384</PDBx:U23>
         <PDBx:U33>0.2617</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="191">
         <PDBx:U11>0.2503</PDBx:U11>
         <PDBx:U12>-0.0170</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.2276</PDBx:U22>
         <PDBx:U23>0.0338</PDBx:U23>
         <PDBx:U33>0.2461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="192">
         <PDBx:U11>0.3158</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>-0.0348</PDBx:U13>
         <PDBx:U22>0.2395</PDBx:U22>
         <PDBx:U23>-0.0359</PDBx:U23>
         <PDBx:U33>0.2555</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="193">
         <PDBx:U11>0.3359</PDBx:U11>
         <PDBx:U12>-0.0233</PDBx:U12>
         <PDBx:U13>-0.0079</PDBx:U13>
         <PDBx:U22>0.2218</PDBx:U22>
         <PDBx:U23>-0.0472</PDBx:U23>
         <PDBx:U33>0.2609</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="194">
         <PDBx:U11>0.5085</PDBx:U11>
         <PDBx:U12>0.1099</PDBx:U12>
         <PDBx:U13>-0.0028</PDBx:U13>
         <PDBx:U22>0.2694</PDBx:U22>
         <PDBx:U23>0.0269</PDBx:U23>
         <PDBx:U33>0.2705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="195">
         <PDBx:U11>0.7065</PDBx:U11>
         <PDBx:U12>0.0297</PDBx:U12>
         <PDBx:U13>-0.1063</PDBx:U13>
         <PDBx:U22>0.5303</PDBx:U22>
         <PDBx:U23>-0.0833</PDBx:U23>
         <PDBx:U33>0.3240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="196">
         <PDBx:U11>0.4553</PDBx:U11>
         <PDBx:U12>-0.0957</PDBx:U12>
         <PDBx:U13>-0.0888</PDBx:U13>
         <PDBx:U22>0.4670</PDBx:U22>
         <PDBx:U23>-0.1346</PDBx:U23>
         <PDBx:U33>0.6579</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="197">
         <PDBx:U11>0.2582</PDBx:U11>
         <PDBx:U12>0.0269</PDBx:U12>
         <PDBx:U13>-0.0055</PDBx:U13>
         <PDBx:U22>0.1971</PDBx:U22>
         <PDBx:U23>0.0083</PDBx:U23>
         <PDBx:U33>0.2121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="198">
         <PDBx:U11>0.2365</PDBx:U11>
         <PDBx:U12>-0.0138</PDBx:U12>
         <PDBx:U13>0.0206</PDBx:U13>
         <PDBx:U22>0.1749</PDBx:U22>
         <PDBx:U23>-0.0013</PDBx:U23>
         <PDBx:U33>0.2722</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="199">
         <PDBx:U11>0.2559</PDBx:U11>
         <PDBx:U12>-0.0353</PDBx:U12>
         <PDBx:U13>-0.0374</PDBx:U13>
         <PDBx:U22>0.2200</PDBx:U22>
         <PDBx:U23>0.0368</PDBx:U23>
         <PDBx:U33>0.2735</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="200">
         <PDBx:U11>0.2505</PDBx:U11>
         <PDBx:U12>-0.0205</PDBx:U12>
         <PDBx:U13>-0.0194</PDBx:U13>
         <PDBx:U22>0.2024</PDBx:U22>
         <PDBx:U23>0.0250</PDBx:U23>
         <PDBx:U33>0.2962</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="201">
         <PDBx:U11>0.2624</PDBx:U11>
         <PDBx:U12>0.0095</PDBx:U12>
         <PDBx:U13>0.0424</PDBx:U13>
         <PDBx:U22>0.2140</PDBx:U22>
         <PDBx:U23>-0.0112</PDBx:U23>
         <PDBx:U33>0.2821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="202">
         <PDBx:U11>0.2787</PDBx:U11>
         <PDBx:U12>0.0023</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.2202</PDBx:U22>
         <PDBx:U23>-0.0106</PDBx:U23>
         <PDBx:U33>0.2524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="203">
         <PDBx:U11>0.3065</PDBx:U11>
         <PDBx:U12>0.0024</PDBx:U12>
         <PDBx:U13>0.0112</PDBx:U13>
         <PDBx:U22>0.2440</PDBx:U22>
         <PDBx:U23>0.0144</PDBx:U23>
         <PDBx:U33>0.2810</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="204">
         <PDBx:U11>0.2589</PDBx:U11>
         <PDBx:U12>0.0209</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.3172</PDBx:U22>
         <PDBx:U23>0.0061</PDBx:U23>
         <PDBx:U33>0.3328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="205">
         <PDBx:U11>0.3105</PDBx:U11>
         <PDBx:U12>0.0210</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.2720</PDBx:U22>
         <PDBx:U23>0.0130</PDBx:U23>
         <PDBx:U33>0.3023</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="206">
         <PDBx:U11>0.3192</PDBx:U11>
         <PDBx:U12>0.0201</PDBx:U12>
         <PDBx:U13>0.0112</PDBx:U13>
         <PDBx:U22>0.3038</PDBx:U22>
         <PDBx:U23>0.0011</PDBx:U23>
         <PDBx:U33>0.3680</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="207">
         <PDBx:U11>0.3325</PDBx:U11>
         <PDBx:U12>0.0429</PDBx:U12>
         <PDBx:U13>0.0410</PDBx:U13>
         <PDBx:U22>0.3101</PDBx:U22>
         <PDBx:U23>0.0029</PDBx:U23>
         <PDBx:U33>0.3780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="208">
         <PDBx:U11>0.3336</PDBx:U11>
         <PDBx:U12>-0.0249</PDBx:U12>
         <PDBx:U13>0.0534</PDBx:U13>
         <PDBx:U22>0.3451</PDBx:U22>
         <PDBx:U23>-0.0152</PDBx:U23>
         <PDBx:U33>0.4679</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="209">
         <PDBx:U11>0.3096</PDBx:U11>
         <PDBx:U12>0.0244</PDBx:U12>
         <PDBx:U13>0.0261</PDBx:U13>
         <PDBx:U22>0.3080</PDBx:U22>
         <PDBx:U23>0.0248</PDBx:U23>
         <PDBx:U33>0.4187</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="210">
         <PDBx:U11>0.3578</PDBx:U11>
         <PDBx:U12>-0.0210</PDBx:U12>
         <PDBx:U13>0.0219</PDBx:U13>
         <PDBx:U22>0.4017</PDBx:U22>
         <PDBx:U23>-0.0296</PDBx:U23>
         <PDBx:U33>0.3647</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="211">
         <PDBx:U11>0.2126</PDBx:U11>
         <PDBx:U12>-0.0201</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.1576</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.2972</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="212">
         <PDBx:U11>0.2648</PDBx:U11>
         <PDBx:U12>-0.0594</PDBx:U12>
         <PDBx:U13>-0.0139</PDBx:U13>
         <PDBx:U22>0.2349</PDBx:U22>
         <PDBx:U23>-0.0146</PDBx:U23>
         <PDBx:U33>0.3373</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="213">
         <PDBx:U11>0.3368</PDBx:U11>
         <PDBx:U12>-0.0172</PDBx:U12>
         <PDBx:U13>-0.0270</PDBx:U13>
         <PDBx:U22>0.2756</PDBx:U22>
         <PDBx:U23>-0.0501</PDBx:U23>
         <PDBx:U33>0.3634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="214">
         <PDBx:U11>0.3083</PDBx:U11>
         <PDBx:U12>-0.0669</PDBx:U12>
         <PDBx:U13>-0.0210</PDBx:U13>
         <PDBx:U22>0.3106</PDBx:U22>
         <PDBx:U23>-0.0121</PDBx:U23>
         <PDBx:U33>0.4169</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="215">
         <PDBx:U11>0.2711</PDBx:U11>
         <PDBx:U12>-0.0496</PDBx:U12>
         <PDBx:U13>0.0162</PDBx:U13>
         <PDBx:U22>0.2600</PDBx:U22>
         <PDBx:U23>0.0192</PDBx:U23>
         <PDBx:U33>0.3559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="216">
         <PDBx:U11>0.3189</PDBx:U11>
         <PDBx:U12>-0.0029</PDBx:U12>
         <PDBx:U13>0.0276</PDBx:U13>
         <PDBx:U22>0.3397</PDBx:U22>
         <PDBx:U23>-0.0118</PDBx:U23>
         <PDBx:U33>0.3550</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="217">
         <PDBx:U11>0.3504</PDBx:U11>
         <PDBx:U12>0.0654</PDBx:U12>
         <PDBx:U13>-0.0148</PDBx:U13>
         <PDBx:U22>0.5155</PDBx:U22>
         <PDBx:U23>-0.0282</PDBx:U23>
         <PDBx:U33>0.6106</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="218">
         <PDBx:U11>0.5432</PDBx:U11>
         <PDBx:U12>-0.1403</PDBx:U12>
         <PDBx:U13>0.0890</PDBx:U13>
         <PDBx:U22>0.6755</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.7059</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="219">
         <PDBx:U11>0.7233</PDBx:U11>
         <PDBx:U12>-0.2306</PDBx:U12>
         <PDBx:U13>-0.0301</PDBx:U13>
         <PDBx:U22>0.8186</PDBx:U22>
         <PDBx:U23>0.1073</PDBx:U23>
         <PDBx:U33>0.5849</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="220">
         <PDBx:U11>0.6688</PDBx:U11>
         <PDBx:U12>-0.1997</PDBx:U12>
         <PDBx:U13>0.0553</PDBx:U13>
         <PDBx:U22>0.7821</PDBx:U22>
         <PDBx:U23>-0.1403</PDBx:U23>
         <PDBx:U33>0.7538</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="221">
         <PDBx:U11>0.8576</PDBx:U11>
         <PDBx:U12>0.0934</PDBx:U12>
         <PDBx:U13>-0.2232</PDBx:U13>
         <PDBx:U22>1.0043</PDBx:U22>
         <PDBx:U23>0.2326</PDBx:U23>
         <PDBx:U33>0.7894</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="222">
         <PDBx:U11>0.3343</PDBx:U11>
         <PDBx:U12>-0.0593</PDBx:U12>
         <PDBx:U13>-0.0319</PDBx:U13>
         <PDBx:U22>0.2051</PDBx:U22>
         <PDBx:U23>-0.0146</PDBx:U23>
         <PDBx:U33>0.3135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="223">
         <PDBx:U11>0.3019</PDBx:U11>
         <PDBx:U12>-0.0197</PDBx:U12>
         <PDBx:U13>-0.0363</PDBx:U13>
         <PDBx:U22>0.2255</PDBx:U22>
         <PDBx:U23>0.0073</PDBx:U23>
         <PDBx:U33>0.2971</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="224">
         <PDBx:U11>0.4081</PDBx:U11>
         <PDBx:U12>0.0492</PDBx:U12>
         <PDBx:U13>-0.0477</PDBx:U13>
         <PDBx:U22>0.2545</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.3641</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="225">
         <PDBx:U11>0.4787</PDBx:U11>
         <PDBx:U12>0.0218</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.3901</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.3648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="226">
         <PDBx:U11>0.3436</PDBx:U11>
         <PDBx:U12>-0.0430</PDBx:U12>
         <PDBx:U13>-0.0559</PDBx:U13>
         <PDBx:U22>0.2229</PDBx:U22>
         <PDBx:U23>-0.0222</PDBx:U23>
         <PDBx:U33>0.3687</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="227">
         <PDBx:U11>0.3326</PDBx:U11>
         <PDBx:U12>-0.0592</PDBx:U12>
         <PDBx:U13>-0.1034</PDBx:U13>
         <PDBx:U22>0.2761</PDBx:U22>
         <PDBx:U23>0.0201</PDBx:U23>
         <PDBx:U33>0.4407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="228">
         <PDBx:U11>0.4023</PDBx:U11>
         <PDBx:U12>-0.0139</PDBx:U12>
         <PDBx:U13>-0.0652</PDBx:U13>
         <PDBx:U22>0.2431</PDBx:U22>
         <PDBx:U23>0.0080</PDBx:U23>
         <PDBx:U33>0.3381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="229">
         <PDBx:U11>0.4756</PDBx:U11>
         <PDBx:U12>0.0052</PDBx:U12>
         <PDBx:U13>-0.0348</PDBx:U13>
         <PDBx:U22>0.3384</PDBx:U22>
         <PDBx:U23>-0.0206</PDBx:U23>
         <PDBx:U33>0.2853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="230">
         <PDBx:U11>0.3358</PDBx:U11>
         <PDBx:U12>-0.0333</PDBx:U12>
         <PDBx:U13>-0.0591</PDBx:U13>
         <PDBx:U22>0.2785</PDBx:U22>
         <PDBx:U23>0.0477</PDBx:U23>
         <PDBx:U33>0.6028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="231">
         <PDBx:U11>0.4394</PDBx:U11>
         <PDBx:U12>-0.0586</PDBx:U12>
         <PDBx:U13>-0.1112</PDBx:U13>
         <PDBx:U22>0.4331</PDBx:U22>
         <PDBx:U23>0.0302</PDBx:U23>
         <PDBx:U33>0.5624</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="232">
         <PDBx:U11>0.3821</PDBx:U11>
         <PDBx:U12>0.0101</PDBx:U12>
         <PDBx:U13>-0.0978</PDBx:U13>
         <PDBx:U22>0.4037</PDBx:U22>
         <PDBx:U23>0.0487</PDBx:U23>
         <PDBx:U33>0.5300</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="233">
         <PDBx:U11>0.4864</PDBx:U11>
         <PDBx:U12>0.1213</PDBx:U12>
         <PDBx:U13>-0.1835</PDBx:U13>
         <PDBx:U22>0.5963</PDBx:U22>
         <PDBx:U23>0.0774</PDBx:U23>
         <PDBx:U33>0.7494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="234">
         <PDBx:U11>0.2710</PDBx:U11>
         <PDBx:U12>0.0098</PDBx:U12>
         <PDBx:U13>-0.0719</PDBx:U13>
         <PDBx:U22>0.3198</PDBx:U22>
         <PDBx:U23>0.0092</PDBx:U23>
         <PDBx:U33>0.5755</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="235">
         <PDBx:U11>0.2989</PDBx:U11>
         <PDBx:U12>-0.0166</PDBx:U12>
         <PDBx:U13>-0.0272</PDBx:U13>
         <PDBx:U22>0.2357</PDBx:U22>
         <PDBx:U23>0.0016</PDBx:U23>
         <PDBx:U33>0.3018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="236">
         <PDBx:U11>0.2976</PDBx:U11>
         <PDBx:U12>-0.0169</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.2181</PDBx:U22>
         <PDBx:U23>0.0096</PDBx:U23>
         <PDBx:U33>0.3542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="237">
         <PDBx:U11>0.3170</PDBx:U11>
         <PDBx:U12>-0.0192</PDBx:U12>
         <PDBx:U13>-0.0096</PDBx:U13>
         <PDBx:U22>0.2227</PDBx:U22>
         <PDBx:U23>0.0448</PDBx:U23>
         <PDBx:U33>0.3013</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="238">
         <PDBx:U11>0.2963</PDBx:U11>
         <PDBx:U12>-0.0004</PDBx:U12>
         <PDBx:U13>-0.0265</PDBx:U13>
         <PDBx:U22>0.2343</PDBx:U22>
         <PDBx:U23>0.0199</PDBx:U23>
         <PDBx:U33>0.2924</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="239">
         <PDBx:U11>0.2946</PDBx:U11>
         <PDBx:U12>-0.0217</PDBx:U12>
         <PDBx:U13>-0.0192</PDBx:U13>
         <PDBx:U22>0.2299</PDBx:U22>
         <PDBx:U23>-0.0189</PDBx:U23>
         <PDBx:U33>0.3557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="240">
         <PDBx:U11>0.2987</PDBx:U11>
         <PDBx:U12>-0.0202</PDBx:U12>
         <PDBx:U13>-0.0150</PDBx:U13>
         <PDBx:U22>0.3018</PDBx:U22>
         <PDBx:U23>0.0184</PDBx:U23>
         <PDBx:U33>0.3629</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="241">
         <PDBx:U11>0.3131</PDBx:U11>
         <PDBx:U12>0.0386</PDBx:U12>
         <PDBx:U13>-0.0298</PDBx:U13>
         <PDBx:U22>0.4043</PDBx:U22>
         <PDBx:U23>0.1008</PDBx:U23>
         <PDBx:U33>0.4784</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="242">
         <PDBx:U11>0.3326</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>-0.0145</PDBx:U13>
         <PDBx:U22>0.3687</PDBx:U22>
         <PDBx:U23>0.0463</PDBx:U23>
         <PDBx:U33>0.4484</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="243">
         <PDBx:U11>0.3860</PDBx:U11>
         <PDBx:U12>-0.0247</PDBx:U12>
         <PDBx:U13>-0.1013</PDBx:U13>
         <PDBx:U22>0.4526</PDBx:U22>
         <PDBx:U23>0.0640</PDBx:U23>
         <PDBx:U33>0.5134</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="244">
         <PDBx:U11>0.3821</PDBx:U11>
         <PDBx:U12>-0.0374</PDBx:U12>
         <PDBx:U13>-0.0275</PDBx:U13>
         <PDBx:U22>0.4120</PDBx:U22>
         <PDBx:U23>0.0094</PDBx:U23>
         <PDBx:U33>0.5151</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="245">
         <PDBx:U11>0.3960</PDBx:U11>
         <PDBx:U12>-0.0525</PDBx:U12>
         <PDBx:U13>-0.0726</PDBx:U13>
         <PDBx:U22>0.4487</PDBx:U22>
         <PDBx:U23>0.0445</PDBx:U23>
         <PDBx:U33>0.5633</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="246">
         <PDBx:U11>0.3916</PDBx:U11>
         <PDBx:U12>-0.0599</PDBx:U12>
         <PDBx:U13>0.0269</PDBx:U13>
         <PDBx:U22>0.5360</PDBx:U22>
         <PDBx:U23>0.0495</PDBx:U23>
         <PDBx:U33>0.6952</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="247">
         <PDBx:U11>0.2750</PDBx:U11>
         <PDBx:U12>-0.0260</PDBx:U12>
         <PDBx:U13>-0.0408</PDBx:U13>
         <PDBx:U22>0.2196</PDBx:U22>
         <PDBx:U23>0.0356</PDBx:U23>
         <PDBx:U33>0.2375</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="248">
         <PDBx:U11>0.2870</PDBx:U11>
         <PDBx:U12>-0.0381</PDBx:U12>
         <PDBx:U13>0.0179</PDBx:U13>
         <PDBx:U22>0.1688</PDBx:U22>
         <PDBx:U23>0.0191</PDBx:U23>
         <PDBx:U33>0.2597</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="249">
         <PDBx:U11>0.2872</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>-0.0225</PDBx:U13>
         <PDBx:U22>0.2530</PDBx:U22>
         <PDBx:U23>0.0101</PDBx:U23>
         <PDBx:U33>0.2437</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="250">
         <PDBx:U11>0.2831</PDBx:U11>
         <PDBx:U12>-0.0176</PDBx:U12>
         <PDBx:U13>-0.0365</PDBx:U13>
         <PDBx:U22>0.2416</PDBx:U22>
         <PDBx:U23>0.0088</PDBx:U23>
         <PDBx:U33>0.2724</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="251">
         <PDBx:U11>0.3516</PDBx:U11>
         <PDBx:U12>-0.0054</PDBx:U12>
         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.1914</PDBx:U22>
         <PDBx:U23>0.0261</PDBx:U23>
         <PDBx:U33>0.2333</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="252">
         <PDBx:U11>0.3748</PDBx:U11>
         <PDBx:U12>-0.0162</PDBx:U12>
         <PDBx:U13>-0.0387</PDBx:U13>
         <PDBx:U22>0.2892</PDBx:U22>
         <PDBx:U23>-0.0109</PDBx:U23>
         <PDBx:U33>0.2619</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="253">
         <PDBx:U11>0.4092</PDBx:U11>
         <PDBx:U12>-0.0256</PDBx:U12>
         <PDBx:U13>-0.0083</PDBx:U13>
         <PDBx:U22>0.2789</PDBx:U22>
         <PDBx:U23>0.0202</PDBx:U23>
         <PDBx:U33>0.2916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="254">
         <PDBx:U11>0.5039</PDBx:U11>
         <PDBx:U12>0.0176</PDBx:U12>
         <PDBx:U13>-0.0676</PDBx:U13>
         <PDBx:U22>0.3395</PDBx:U22>
         <PDBx:U23>0.0503</PDBx:U23>
         <PDBx:U33>0.3175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="255">
         <PDBx:U11>0.2649</PDBx:U11>
         <PDBx:U12>-0.0214</PDBx:U12>
         <PDBx:U13>-0.0116</PDBx:U13>
         <PDBx:U22>0.1771</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.2428</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="256">
         <PDBx:U11>0.2727</PDBx:U11>
         <PDBx:U12>-0.0417</PDBx:U12>
         <PDBx:U13>-0.0201</PDBx:U13>
         <PDBx:U22>0.1522</PDBx:U22>
         <PDBx:U23>0.0133</PDBx:U23>
         <PDBx:U33>0.2152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="257">
         <PDBx:U11>0.2672</PDBx:U11>
         <PDBx:U12>-0.0143</PDBx:U12>
         <PDBx:U13>0.0281</PDBx:U13>
         <PDBx:U22>0.1796</PDBx:U22>
         <PDBx:U23>0.0174</PDBx:U23>
         <PDBx:U33>0.2440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="258">
         <PDBx:U11>0.2481</PDBx:U11>
         <PDBx:U12>-0.0414</PDBx:U12>
         <PDBx:U13>0.0317</PDBx:U13>
         <PDBx:U22>0.1756</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.2564</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="259">
         <PDBx:U11>0.2436</PDBx:U11>
         <PDBx:U12>0.0042</PDBx:U12>
         <PDBx:U13>-0.0119</PDBx:U13>
         <PDBx:U22>0.1747</PDBx:U22>
         <PDBx:U23>0.0427</PDBx:U23>
         <PDBx:U33>0.2466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="260">
         <PDBx:U11>0.2254</PDBx:U11>
         <PDBx:U12>-0.0033</PDBx:U12>
         <PDBx:U13>-0.0074</PDBx:U13>
         <PDBx:U22>0.2240</PDBx:U22>
         <PDBx:U23>0.0075</PDBx:U23>
         <PDBx:U33>0.2730</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="261">
         <PDBx:U11>0.2720</PDBx:U11>
         <PDBx:U12>0.0042</PDBx:U12>
         <PDBx:U13>-0.0273</PDBx:U13>
         <PDBx:U22>0.1649</PDBx:U22>
         <PDBx:U23>0.0094</PDBx:U23>
         <PDBx:U33>0.2503</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="262">
         <PDBx:U11>0.2478</PDBx:U11>
         <PDBx:U12>-0.0119</PDBx:U12>
         <PDBx:U13>0.0088</PDBx:U13>
         <PDBx:U22>0.1540</PDBx:U22>
         <PDBx:U23>0.0048</PDBx:U23>
         <PDBx:U33>0.2384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="263">
         <PDBx:U11>0.2409</PDBx:U11>
         <PDBx:U12>-0.0237</PDBx:U12>
         <PDBx:U13>0.0077</PDBx:U13>
         <PDBx:U22>0.1715</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.2039</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="264">
         <PDBx:U11>0.2237</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.1514</PDBx:U22>
         <PDBx:U23>0.0201</PDBx:U23>
         <PDBx:U33>0.2324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="265">
         <PDBx:U11>0.2230</PDBx:U11>
         <PDBx:U12>-0.0232</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.1915</PDBx:U22>
         <PDBx:U23>0.0066</PDBx:U23>
         <PDBx:U33>0.2234</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="266">
         <PDBx:U11>0.2642</PDBx:U11>
         <PDBx:U12>0.0033</PDBx:U12>
         <PDBx:U13>-0.0340</PDBx:U13>
         <PDBx:U22>0.1539</PDBx:U22>
         <PDBx:U23>0.0099</PDBx:U23>
         <PDBx:U33>0.2307</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="267">
         <PDBx:U11>0.2287</PDBx:U11>
         <PDBx:U12>0.0129</PDBx:U12>
         <PDBx:U13>0.0091</PDBx:U13>
         <PDBx:U22>0.1454</PDBx:U22>
         <PDBx:U23>0.0160</PDBx:U23>
         <PDBx:U33>0.1961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="268">
         <PDBx:U11>0.2588</PDBx:U11>
         <PDBx:U12>-0.0020</PDBx:U12>
         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.1531</PDBx:U22>
         <PDBx:U23>0.0224</PDBx:U23>
         <PDBx:U33>0.2025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="269">
         <PDBx:U11>0.2413</PDBx:U11>
         <PDBx:U12>0.0056</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.1987</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.2483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="270">
         <PDBx:U11>0.2381</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.2068</PDBx:U22>
         <PDBx:U23>0.0130</PDBx:U23>
         <PDBx:U33>0.2474</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="271">
         <PDBx:U11>0.2518</PDBx:U11>
         <PDBx:U12>-0.0054</PDBx:U12>
         <PDBx:U13>-0.0201</PDBx:U13>
         <PDBx:U22>0.1720</PDBx:U22>
         <PDBx:U23>0.0409</PDBx:U23>
         <PDBx:U33>0.2363</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="272">
         <PDBx:U11>0.2526</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1858</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.2595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="273">
         <PDBx:U11>0.3327</PDBx:U11>
         <PDBx:U12>0.0047</PDBx:U12>
         <PDBx:U13>-0.0118</PDBx:U13>
         <PDBx:U22>0.2251</PDBx:U22>
         <PDBx:U23>0.0438</PDBx:U23>
         <PDBx:U33>0.2311</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="274">
         <PDBx:U11>0.3308</PDBx:U11>
         <PDBx:U12>0.0329</PDBx:U12>
         <PDBx:U13>-0.0280</PDBx:U13>
         <PDBx:U22>0.2335</PDBx:U22>
         <PDBx:U23>-0.0361</PDBx:U23>
         <PDBx:U33>0.3280</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="275">
         <PDBx:U11>0.2291</PDBx:U11>
         <PDBx:U12>0.0018</PDBx:U12>
         <PDBx:U13>0.0091</PDBx:U13>
         <PDBx:U22>0.1781</PDBx:U22>
         <PDBx:U23>0.0155</PDBx:U23>
         <PDBx:U33>0.2177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="276">
         <PDBx:U11>0.2406</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.1583</PDBx:U22>
         <PDBx:U23>-0.0269</PDBx:U23>
         <PDBx:U33>0.2387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="277">
         <PDBx:U11>0.2271</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.1821</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.2330</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="278">
         <PDBx:U11>0.2325</PDBx:U11>
         <PDBx:U12>0.0166</PDBx:U12>
         <PDBx:U13>0.0121</PDBx:U13>
         <PDBx:U22>0.2069</PDBx:U22>
         <PDBx:U23>0.0135</PDBx:U23>
         <PDBx:U33>0.2425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="279">
         <PDBx:U11>0.2577</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.1413</PDBx:U22>
         <PDBx:U23>-0.0248</PDBx:U23>
         <PDBx:U33>0.2304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="280">
         <PDBx:U11>0.2878</PDBx:U11>
         <PDBx:U12>0.0478</PDBx:U12>
         <PDBx:U13>-0.0257</PDBx:U13>
         <PDBx:U22>0.2080</PDBx:U22>
         <PDBx:U23>-0.0138</PDBx:U23>
         <PDBx:U33>0.2510</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="281">
         <PDBx:U11>0.3048</PDBx:U11>
         <PDBx:U12>0.0192</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.1769</PDBx:U22>
         <PDBx:U23>0.0189</PDBx:U23>
         <PDBx:U33>0.2834</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="282">
         <PDBx:U11>0.2548</PDBx:U11>
         <PDBx:U12>0.0263</PDBx:U12>
         <PDBx:U13>-0.0111</PDBx:U13>
         <PDBx:U22>0.2072</PDBx:U22>
         <PDBx:U23>0.0036</PDBx:U23>
         <PDBx:U33>0.2032</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="283">
         <PDBx:U11>0.2956</PDBx:U11>
         <PDBx:U12>0.0206</PDBx:U12>
         <PDBx:U13>0.0203</PDBx:U13>
         <PDBx:U22>0.1792</PDBx:U22>
         <PDBx:U23>0.0175</PDBx:U23>
         <PDBx:U33>0.2207</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="284">
         <PDBx:U11>0.2360</PDBx:U11>
         <PDBx:U12>0.0072</PDBx:U12>
         <PDBx:U13>-0.0327</PDBx:U13>
         <PDBx:U22>0.1670</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.2181</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="285">
         <PDBx:U11>0.2111</PDBx:U11>
         <PDBx:U12>0.0166</PDBx:U12>
         <PDBx:U13>-0.0270</PDBx:U13>
         <PDBx:U22>0.1835</PDBx:U22>
         <PDBx:U23>0.0045</PDBx:U23>
         <PDBx:U33>0.2488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="286">
         <PDBx:U11>0.2658</PDBx:U11>
         <PDBx:U12>-0.0075</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.2103</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.2249</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="287">
         <PDBx:U11>0.2587</PDBx:U11>
         <PDBx:U12>-0.0287</PDBx:U12>
         <PDBx:U13>-0.0080</PDBx:U13>
         <PDBx:U22>0.2139</PDBx:U22>
         <PDBx:U23>-0.0267</PDBx:U23>
         <PDBx:U33>0.2739</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="288">
         <PDBx:U11>0.2112</PDBx:U11>
         <PDBx:U12>0.0019</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.1993</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.2816</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="289">
         <PDBx:U11>0.3265</PDBx:U11>
         <PDBx:U12>0.0465</PDBx:U12>
         <PDBx:U13>-0.0260</PDBx:U13>
         <PDBx:U22>0.2300</PDBx:U22>
         <PDBx:U23>-0.0498</PDBx:U23>
         <PDBx:U33>0.3192</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="290">
         <PDBx:U11>0.3294</PDBx:U11>
         <PDBx:U12>0.0358</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.2579</PDBx:U22>
         <PDBx:U23>-0.0500</PDBx:U23>
         <PDBx:U33>0.3474</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="291">
         <PDBx:U11>0.4804</PDBx:U11>
         <PDBx:U12>-0.0491</PDBx:U12>
         <PDBx:U13>-0.0439</PDBx:U13>
         <PDBx:U22>0.3090</PDBx:U22>
         <PDBx:U23>0.0398</PDBx:U23>
         <PDBx:U33>0.4023</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="292">
         <PDBx:U11>0.2603</PDBx:U11>
         <PDBx:U12>0.0200</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.2213</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.2377</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="293">
         <PDBx:U11>0.2451</PDBx:U11>
         <PDBx:U12>-0.0074</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.1878</PDBx:U22>
         <PDBx:U23>0.0099</PDBx:U23>
         <PDBx:U33>0.2521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="294">
         <PDBx:U11>0.2490</PDBx:U11>
         <PDBx:U12>0.0077</PDBx:U12>
         <PDBx:U13>0.0038</PDBx:U13>
         <PDBx:U22>0.2025</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.2860</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="295">
         <PDBx:U11>0.2725</PDBx:U11>
         <PDBx:U12>0.0063</PDBx:U12>
         <PDBx:U13>-0.0128</PDBx:U13>
         <PDBx:U22>0.1945</PDBx:U22>
         <PDBx:U23>0.0066</PDBx:U23>
         <PDBx:U33>0.2945</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="296">
         <PDBx:U11>0.2689</PDBx:U11>
         <PDBx:U12>0.0047</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.1791</PDBx:U22>
         <PDBx:U23>-0.0099</PDBx:U23>
         <PDBx:U33>0.2393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="297">
         <PDBx:U11>0.2631</PDBx:U11>
         <PDBx:U12>-0.0235</PDBx:U12>
         <PDBx:U13>-0.0094</PDBx:U13>
         <PDBx:U22>0.1779</PDBx:U22>
         <PDBx:U23>0.0280</PDBx:U23>
         <PDBx:U33>0.2355</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="298">
         <PDBx:U11>0.3136</PDBx:U11>
         <PDBx:U12>0.0323</PDBx:U12>
         <PDBx:U13>-0.0071</PDBx:U13>
         <PDBx:U22>0.1991</PDBx:U22>
         <PDBx:U23>-0.0372</PDBx:U23>
         <PDBx:U33>0.2435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="299">
         <PDBx:U11>0.2687</PDBx:U11>
         <PDBx:U12>-0.0064</PDBx:U12>
         <PDBx:U13>-0.0149</PDBx:U13>
         <PDBx:U22>0.1748</PDBx:U22>
         <PDBx:U23>0.0369</PDBx:U23>
         <PDBx:U33>0.2654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="300">
         <PDBx:U11>0.2685</PDBx:U11>
         <PDBx:U12>-0.0122</PDBx:U12>
         <PDBx:U13>-0.0404</PDBx:U13>
         <PDBx:U22>0.2177</PDBx:U22>
         <PDBx:U23>-0.0180</PDBx:U23>
         <PDBx:U33>0.2368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="301">
         <PDBx:U11>0.2900</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>-0.0628</PDBx:U13>
         <PDBx:U22>0.2845</PDBx:U22>
         <PDBx:U23>0.0210</PDBx:U23>
         <PDBx:U33>0.2884</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="302">
         <PDBx:U11>0.2433</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>-0.0064</PDBx:U13>
         <PDBx:U22>0.2329</PDBx:U22>
         <PDBx:U23>0.0350</PDBx:U23>
         <PDBx:U33>0.2901</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="303">
         <PDBx:U11>0.2590</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>-0.0367</PDBx:U13>
         <PDBx:U22>0.2224</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.2670</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="304">
         <PDBx:U11>0.2449</PDBx:U11>
         <PDBx:U12>0.0148</PDBx:U12>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0297</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0281</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.0008</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:U23>0.0078</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U12>-0.0244</PDBx:U12>
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         <PDBx:U22>0.2299</PDBx:U22>
         <PDBx:U23>-0.0169</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>-0.0273</PDBx:U13>
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         <PDBx:U23>-0.0216</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0066</PDBx:U23>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.1710</PDBx:U22>
         <PDBx:U23>0.0038</PDBx:U23>
         <PDBx:U33>0.2663</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0470</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0717</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0520</PDBx:U23>
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         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.0109</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.3214</PDBx:U11>
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         <PDBx:U23>0.0249</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0036</PDBx:U23>
         <PDBx:U33>0.2247</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0019</PDBx:U23>
         <PDBx:U33>0.2138</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="341">
         <PDBx:U11>0.3879</PDBx:U11>
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         <PDBx:U13>-0.0100</PDBx:U13>
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         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.2184</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="342">
         <PDBx:U11>0.3117</PDBx:U11>
         <PDBx:U12>-0.0138</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.1691</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.2657</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.2866</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>0.0225</PDBx:U13>
         <PDBx:U22>0.1828</PDBx:U22>
         <PDBx:U23>-0.0566</PDBx:U23>
         <PDBx:U33>0.2657</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="344">
         <PDBx:U11>0.2937</PDBx:U11>
         <PDBx:U12>0.0068</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.2355</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.2404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>-0.0075</PDBx:U13>
         <PDBx:U22>0.2105</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.2170</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="346">
         <PDBx:U11>0.3137</PDBx:U11>
         <PDBx:U12>-0.0035</PDBx:U12>
         <PDBx:U13>0.0499</PDBx:U13>
         <PDBx:U22>0.1943</PDBx:U22>
         <PDBx:U23>-0.0421</PDBx:U23>
         <PDBx:U33>0.3416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="347">
         <PDBx:U11>0.3609</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>0.0705</PDBx:U13>
         <PDBx:U22>0.1865</PDBx:U22>
         <PDBx:U23>-0.0120</PDBx:U23>
         <PDBx:U33>0.3027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="348">
         <PDBx:U11>0.4663</PDBx:U11>
         <PDBx:U12>0.0875</PDBx:U12>
         <PDBx:U13>0.0694</PDBx:U13>
         <PDBx:U22>0.3053</PDBx:U22>
         <PDBx:U23>0.0341</PDBx:U23>
         <PDBx:U33>0.4172</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="349">
         <PDBx:U11>0.3774</PDBx:U11>
         <PDBx:U12>0.0141</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.2196</PDBx:U22>
         <PDBx:U23>-0.0376</PDBx:U23>
         <PDBx:U33>0.3424</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="350">
         <PDBx:U11>0.5209</PDBx:U11>
         <PDBx:U12>0.0981</PDBx:U12>
         <PDBx:U13>0.1349</PDBx:U13>
         <PDBx:U22>0.2757</PDBx:U22>
         <PDBx:U23>0.0512</PDBx:U23>
         <PDBx:U33>0.4793</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="351">
         <PDBx:U11>0.3694</PDBx:U11>
         <PDBx:U12>-0.0049</PDBx:U12>
         <PDBx:U13>0.0161</PDBx:U13>
         <PDBx:U22>0.1931</PDBx:U22>
         <PDBx:U23>0.0181</PDBx:U23>
         <PDBx:U33>0.2603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="352">
         <PDBx:U11>0.3319</PDBx:U11>
         <PDBx:U12>-0.0011</PDBx:U12>
         <PDBx:U13>-0.0252</PDBx:U13>
         <PDBx:U22>0.2410</PDBx:U22>
         <PDBx:U23>0.0160</PDBx:U23>
         <PDBx:U33>0.2113</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="370">
         <PDBx:U11>0.3448</PDBx:U11>
         <PDBx:U12>-0.0413</PDBx:U12>
         <PDBx:U13>-0.0321</PDBx:U13>
         <PDBx:U22>0.2317</PDBx:U22>
         <PDBx:U23>-0.0379</PDBx:U23>
         <PDBx:U33>0.2777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="371">
         <PDBx:U11>0.3666</PDBx:U11>
         <PDBx:U12>0.0125</PDBx:U12>
         <PDBx:U13>-0.0216</PDBx:U13>
         <PDBx:U22>0.2596</PDBx:U22>
         <PDBx:U23>-0.0552</PDBx:U23>
         <PDBx:U33>0.3127</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="372">
         <PDBx:U11>0.2743</PDBx:U11>
         <PDBx:U12>-0.0360</PDBx:U12>
         <PDBx:U13>0.0104</PDBx:U13>
         <PDBx:U22>0.2094</PDBx:U22>
         <PDBx:U23>-0.0509</PDBx:U23>
         <PDBx:U33>0.2094</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="373">
         <PDBx:U11>0.3276</PDBx:U11>
         <PDBx:U12>-0.0102</PDBx:U12>
         <PDBx:U13>-0.0178</PDBx:U13>
         <PDBx:U22>0.2411</PDBx:U22>
         <PDBx:U23>-0.0252</PDBx:U23>
         <PDBx:U33>0.2028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="374">
         <PDBx:U11>0.3206</PDBx:U11>
         <PDBx:U12>-0.0182</PDBx:U12>
         <PDBx:U13>-0.0151</PDBx:U13>
         <PDBx:U22>0.2098</PDBx:U22>
         <PDBx:U23>0.0075</PDBx:U23>
         <PDBx:U33>0.2226</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="375">
         <PDBx:U11>0.2938</PDBx:U11>
         <PDBx:U12>0.0039</PDBx:U12>
         <PDBx:U13>-0.0158</PDBx:U13>
         <PDBx:U22>0.2383</PDBx:U22>
         <PDBx:U23>-0.0461</PDBx:U23>
         <PDBx:U33>0.2521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="376">
         <PDBx:U11>0.3497</PDBx:U11>
         <PDBx:U12>-0.0261</PDBx:U12>
         <PDBx:U13>-0.0247</PDBx:U13>
         <PDBx:U22>0.2401</PDBx:U22>
         <PDBx:U23>0.0216</PDBx:U23>
         <PDBx:U33>0.2210</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="377">
         <PDBx:U11>0.3306</PDBx:U11>
         <PDBx:U12>-0.0074</PDBx:U12>
         <PDBx:U13>-0.0205</PDBx:U13>
         <PDBx:U22>0.2525</PDBx:U22>
         <PDBx:U23>-0.0016</PDBx:U23>
         <PDBx:U33>0.2100</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="378">
         <PDBx:U11>0.2896</PDBx:U11>
         <PDBx:U12>0.0264</PDBx:U12>
         <PDBx:U13>0.0237</PDBx:U13>
         <PDBx:U22>0.2571</PDBx:U22>
         <PDBx:U23>-0.0085</PDBx:U23>
         <PDBx:U33>0.2806</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="379">
         <PDBx:U11>0.3183</PDBx:U11>
         <PDBx:U12>-0.0355</PDBx:U12>
         <PDBx:U13>0.0388</PDBx:U13>
         <PDBx:U22>0.2017</PDBx:U22>
         <PDBx:U23>-0.0362</PDBx:U23>
         <PDBx:U33>0.2835</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="380">
         <PDBx:U11>0.3406</PDBx:U11>
         <PDBx:U12>-0.0427</PDBx:U12>
         <PDBx:U13>-0.0323</PDBx:U13>
         <PDBx:U22>0.1865</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.3258</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="381">
         <PDBx:U11>0.3763</PDBx:U11>
         <PDBx:U12>0.0121</PDBx:U12>
         <PDBx:U13>-0.0543</PDBx:U13>
         <PDBx:U22>0.3132</PDBx:U22>
         <PDBx:U23>-0.0656</PDBx:U23>
         <PDBx:U33>0.3792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="382">
         <PDBx:U11>0.3647</PDBx:U11>
         <PDBx:U12>-0.0632</PDBx:U12>
         <PDBx:U13>-0.0204</PDBx:U13>
         <PDBx:U22>0.3094</PDBx:U22>
         <PDBx:U23>-0.0282</PDBx:U23>
         <PDBx:U33>0.3520</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="383">
         <PDBx:U11>0.3365</PDBx:U11>
         <PDBx:U12>-0.0341</PDBx:U12>
         <PDBx:U13>-0.0112</PDBx:U13>
         <PDBx:U22>0.1659</PDBx:U22>
         <PDBx:U23>0.0135</PDBx:U23>
         <PDBx:U33>0.4171</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="384">
         <PDBx:U11>0.3865</PDBx:U11>
         <PDBx:U12>-0.0342</PDBx:U12>
         <PDBx:U13>-0.0232</PDBx:U13>
         <PDBx:U22>0.2640</PDBx:U22>
         <PDBx:U23>-0.0145</PDBx:U23>
         <PDBx:U33>0.3385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="385">
         <PDBx:U11>0.3393</PDBx:U11>
         <PDBx:U12>-0.0851</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.2558</PDBx:U22>
         <PDBx:U23>-0.0380</PDBx:U23>
         <PDBx:U33>0.4099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:U33>0.8590</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="419">
         <PDBx:U11>0.5817</PDBx:U11>
         <PDBx:U12>-0.0169</PDBx:U12>
         <PDBx:U13>0.1215</PDBx:U13>
         <PDBx:U22>0.5146</PDBx:U22>
         <PDBx:U23>-0.0166</PDBx:U23>
         <PDBx:U33>0.3517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="420">
         <PDBx:U11>0.4720</PDBx:U11>
         <PDBx:U12>-0.0238</PDBx:U12>
         <PDBx:U13>0.0501</PDBx:U13>
         <PDBx:U22>0.5775</PDBx:U22>
         <PDBx:U23>0.0095</PDBx:U23>
         <PDBx:U33>0.3755</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="421">
         <PDBx:U11>0.3973</PDBx:U11>
         <PDBx:U12>0.1315</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.5144</PDBx:U22>
         <PDBx:U23>0.0301</PDBx:U23>
         <PDBx:U33>0.3255</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="422">
         <PDBx:U11>0.3665</PDBx:U11>
         <PDBx:U12>0.1434</PDBx:U12>
         <PDBx:U13>-0.0383</PDBx:U13>
         <PDBx:U22>0.5706</PDBx:U22>
         <PDBx:U23>-0.0932</PDBx:U23>
         <PDBx:U33>0.3541</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="423">
         <PDBx:U11>0.5837</PDBx:U11>
         <PDBx:U12>0.0973</PDBx:U12>
         <PDBx:U13>0.0863</PDBx:U13>
         <PDBx:U22>0.5294</PDBx:U22>
         <PDBx:U23>-0.1382</PDBx:U23>
         <PDBx:U33>0.4057</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="424">
         <PDBx:U11>0.5495</PDBx:U11>
         <PDBx:U12>-0.0045</PDBx:U12>
         <PDBx:U13>0.0312</PDBx:U13>
         <PDBx:U22>0.5860</PDBx:U22>
         <PDBx:U23>-0.0229</PDBx:U23>
         <PDBx:U33>0.4556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="425">
         <PDBx:U11>0.5658</PDBx:U11>
         <PDBx:U12>0.0190</PDBx:U12>
         <PDBx:U13>0.0883</PDBx:U13>
         <PDBx:U22>0.6213</PDBx:U22>
         <PDBx:U23>0.0475</PDBx:U23>
         <PDBx:U33>0.4583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="426">
         <PDBx:U11>0.4065</PDBx:U11>
         <PDBx:U12>0.0038</PDBx:U12>
         <PDBx:U13>0.0191</PDBx:U13>
         <PDBx:U22>0.3703</PDBx:U22>
         <PDBx:U23>-0.0546</PDBx:U23>
         <PDBx:U33>0.3435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="427">
         <PDBx:U11>0.3751</PDBx:U11>
         <PDBx:U12>0.0037</PDBx:U12>
         <PDBx:U13>-0.0128</PDBx:U13>
         <PDBx:U22>0.3299</PDBx:U22>
         <PDBx:U23>-0.0162</PDBx:U23>
         <PDBx:U33>0.3367</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="428">
         <PDBx:U11>0.3403</PDBx:U11>
         <PDBx:U12>0.0115</PDBx:U12>
         <PDBx:U13>-0.0175</PDBx:U13>
         <PDBx:U22>0.3640</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.3404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="429">
         <PDBx:U11>0.3466</PDBx:U11>
         <PDBx:U12>0.0166</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.3608</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.3301</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="430">
         <PDBx:U11>0.3813</PDBx:U11>
         <PDBx:U12>-0.0098</PDBx:U12>
         <PDBx:U13>0.0399</PDBx:U13>
         <PDBx:U22>0.5049</PDBx:U22>
         <PDBx:U23>0.0484</PDBx:U23>
         <PDBx:U33>0.3603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="431">
         <PDBx:U11>0.4556</PDBx:U11>
         <PDBx:U12>0.0791</PDBx:U12>
         <PDBx:U13>-0.0567</PDBx:U13>
         <PDBx:U22>0.5046</PDBx:U22>
         <PDBx:U23>0.0380</PDBx:U23>
         <PDBx:U33>0.2973</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="432">
         <PDBx:U11>0.4573</PDBx:U11>
         <PDBx:U12>-0.0643</PDBx:U12>
         <PDBx:U13>-0.0220</PDBx:U13>
         <PDBx:U22>0.7539</PDBx:U22>
         <PDBx:U23>0.1054</PDBx:U23>
         <PDBx:U33>0.4438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="433">
         <PDBx:U11>0.5350</PDBx:U11>
         <PDBx:U12>0.2540</PDBx:U12>
         <PDBx:U13>-0.0601</PDBx:U13>
         <PDBx:U22>0.6037</PDBx:U22>
         <PDBx:U23>-0.0435</PDBx:U23>
         <PDBx:U33>0.3566</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="434">
         <PDBx:U11>0.2948</PDBx:U11>
         <PDBx:U12>0.0112</PDBx:U12>
         <PDBx:U13>-0.0053</PDBx:U13>
         <PDBx:U22>0.3808</PDBx:U22>
         <PDBx:U23>0.0236</PDBx:U23>
         <PDBx:U33>0.3083</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:U23>0.0056</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.0311</PDBx:U23>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U22>0.2246</PDBx:U22>
         <PDBx:U23>0.0113</PDBx:U23>
         <PDBx:U33>0.3575</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.2173</PDBx:U22>
         <PDBx:U23>-0.0057</PDBx:U23>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0103</PDBx:U23>
         <PDBx:U33>0.3129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U22>0.4739</PDBx:U22>
         <PDBx:U23>0.0711</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.6086</PDBx:U22>
         <PDBx:U23>0.0377</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0563</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="484">
         <PDBx:U11>0.2194</PDBx:U11>
         <PDBx:U12>-0.0318</PDBx:U12>
         <PDBx:U13>-0.0384</PDBx:U13>
         <PDBx:U22>0.1484</PDBx:U22>
         <PDBx:U23>0.0070</PDBx:U23>
         <PDBx:U33>0.2643</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="485">
         <PDBx:U11>0.2256</PDBx:U11>
         <PDBx:U12>-0.0190</PDBx:U12>
         <PDBx:U13>-0.0262</PDBx:U13>
         <PDBx:U22>0.1929</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.2634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="486">
         <PDBx:U11>0.2065</PDBx:U11>
         <PDBx:U12>-0.0084</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.1663</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.2299</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="487">
         <PDBx:U11>0.2431</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>-0.0614</PDBx:U13>
         <PDBx:U22>0.1479</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.2884</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="488">
         <PDBx:U11>0.2391</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>-0.0237</PDBx:U13>
         <PDBx:U22>0.2000</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.2683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="489">
         <PDBx:U11>0.2578</PDBx:U11>
         <PDBx:U12>-0.0141</PDBx:U12>
         <PDBx:U13>-0.0200</PDBx:U13>
         <PDBx:U22>0.1954</PDBx:U22>
         <PDBx:U23>0.0077</PDBx:U23>
         <PDBx:U33>0.2636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="490">
         <PDBx:U11>0.2784</PDBx:U11>
         <PDBx:U12>0.0182</PDBx:U12>
         <PDBx:U13>-0.0472</PDBx:U13>
         <PDBx:U22>0.2352</PDBx:U22>
         <PDBx:U23>0.0245</PDBx:U23>
         <PDBx:U33>0.2989</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="491">
         <PDBx:U11>0.3338</PDBx:U11>
         <PDBx:U12>0.0257</PDBx:U12>
         <PDBx:U13>-0.0335</PDBx:U13>
         <PDBx:U22>0.2272</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.3240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="492">
         <PDBx:U11>0.2358</PDBx:U11>
         <PDBx:U12>0.0228</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.1877</PDBx:U22>
         <PDBx:U23>0.0129</PDBx:U23>
         <PDBx:U33>0.2822</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="493">
         <PDBx:U11>0.2382</PDBx:U11>
         <PDBx:U12>-0.0378</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.1487</PDBx:U22>
         <PDBx:U23>0.0155</PDBx:U23>
         <PDBx:U33>0.2277</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="494">
         <PDBx:U11>0.2339</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>-0.0097</PDBx:U13>
         <PDBx:U22>0.1607</PDBx:U22>
         <PDBx:U23>0.0233</PDBx:U23>
         <PDBx:U33>0.2202</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="495">
         <PDBx:U11>0.2136</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>-0.0182</PDBx:U13>
         <PDBx:U22>0.2103</PDBx:U22>
         <PDBx:U23>0.0314</PDBx:U23>
         <PDBx:U33>0.2768</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="496">
         <PDBx:U11>0.2615</PDBx:U11>
         <PDBx:U12>-0.0541</PDBx:U12>
         <PDBx:U13>0.0904</PDBx:U13>
         <PDBx:U22>0.2607</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.3112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="497">
         <PDBx:U11>0.2892</PDBx:U11>
         <PDBx:U12>-0.0593</PDBx:U12>
         <PDBx:U13>0.0897</PDBx:U13>
         <PDBx:U22>0.2981</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.3400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="498">
         <PDBx:U11>0.2670</PDBx:U11>
         <PDBx:U12>-0.0554</PDBx:U12>
         <PDBx:U13>0.0651</PDBx:U13>
         <PDBx:U22>0.4052</PDBx:U22>
         <PDBx:U23>-0.0168</PDBx:U23>
         <PDBx:U33>0.2694</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="499">
         <PDBx:U11>0.2843</PDBx:U11>
         <PDBx:U12>0.0054</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.2067</PDBx:U22>
         <PDBx:U23>-0.0288</PDBx:U23>
         <PDBx:U33>0.2836</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>81</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="500">
         <PDBx:U11>0.2586</PDBx:U11>
         <PDBx:U12>0.0094</PDBx:U12>
         <PDBx:U13>-0.0119</PDBx:U13>
         <PDBx:U22>0.1728</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.2265</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="501">
         <PDBx:U11>0.2420</PDBx:U11>
         <PDBx:U12>0.0061</PDBx:U12>
         <PDBx:U13>-0.0108</PDBx:U13>
         <PDBx:U22>0.1606</PDBx:U22>
         <PDBx:U23>0.0138</PDBx:U23>
         <PDBx:U33>0.2418</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="502">
         <PDBx:U11>0.2539</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>-0.0039</PDBx:U13>
         <PDBx:U22>0.1826</PDBx:U22>
         <PDBx:U23>0.0122</PDBx:U23>
         <PDBx:U33>0.2584</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="503">
         <PDBx:U11>0.3535</PDBx:U11>
         <PDBx:U12>-0.0310</PDBx:U12>
         <PDBx:U13>-0.0302</PDBx:U13>
         <PDBx:U22>0.2065</PDBx:U22>
         <PDBx:U23>0.0181</PDBx:U23>
         <PDBx:U33>0.2711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="504">
         <PDBx:U11>0.2387</PDBx:U11>
         <PDBx:U12>0.0169</PDBx:U12>
         <PDBx:U13>-0.0156</PDBx:U13>
         <PDBx:U22>0.1799</PDBx:U22>
         <PDBx:U23>0.0092</PDBx:U23>
         <PDBx:U33>0.2568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="505">
         <PDBx:U11>0.3254</PDBx:U11>
         <PDBx:U12>0.0307</PDBx:U12>
         <PDBx:U13>-0.0094</PDBx:U13>
         <PDBx:U22>0.1958</PDBx:U22>
         <PDBx:U23>0.0126</PDBx:U23>
         <PDBx:U33>0.3112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="506">
         <PDBx:U11>0.2639</PDBx:U11>
         <PDBx:U12>-0.0172</PDBx:U12>
         <PDBx:U13>0.0123</PDBx:U13>
         <PDBx:U22>0.1930</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.2649</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>82</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="507">
         <PDBx:U11>0.2301</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>0.0147</PDBx:U13>
         <PDBx:U22>0.1755</PDBx:U22>
         <PDBx:U23>0.0307</PDBx:U23>
         <PDBx:U33>0.3450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="508">
         <PDBx:U11>0.2437</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>0.0204</PDBx:U13>
         <PDBx:U22>0.2127</PDBx:U22>
         <PDBx:U23>0.0346</PDBx:U23>
         <PDBx:U33>0.2977</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="509">
         <PDBx:U11>0.2898</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0187</PDBx:U13>
         <PDBx:U22>0.2215</PDBx:U22>
         <PDBx:U23>0.0216</PDBx:U23>
         <PDBx:U33>0.2868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="510">
         <PDBx:U11>0.3011</PDBx:U11>
         <PDBx:U12>0.0465</PDBx:U12>
         <PDBx:U13>0.0517</PDBx:U13>
         <PDBx:U22>0.2754</PDBx:U22>
         <PDBx:U23>0.0273</PDBx:U23>
         <PDBx:U33>0.3011</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="511">
         <PDBx:U11>0.2639</PDBx:U11>
         <PDBx:U12>-0.0424</PDBx:U12>
         <PDBx:U13>0.0243</PDBx:U13>
         <PDBx:U22>0.2454</PDBx:U22>
         <PDBx:U23>0.0446</PDBx:U23>
         <PDBx:U33>0.3702</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="512">
         <PDBx:U11>0.3102</PDBx:U11>
         <PDBx:U12>-0.0467</PDBx:U12>
         <PDBx:U13>0.0303</PDBx:U13>
         <PDBx:U22>0.2006</PDBx:U22>
         <PDBx:U23>0.0433</PDBx:U23>
         <PDBx:U33>0.3673</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="513">
         <PDBx:U11>0.3098</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>0.0332</PDBx:U13>
         <PDBx:U22>0.2488</PDBx:U22>
         <PDBx:U23>0.0351</PDBx:U23>
         <PDBx:U33>0.4004</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="514">
         <PDBx:U11>0.2744</PDBx:U11>
         <PDBx:U12>-0.0138</PDBx:U12>
         <PDBx:U13>-0.0165</PDBx:U13>
         <PDBx:U22>0.2833</PDBx:U22>
         <PDBx:U23>0.0417</PDBx:U23>
         <PDBx:U33>0.3872</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="515">
         <PDBx:U11>0.3259</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>0.0387</PDBx:U13>
         <PDBx:U22>0.3385</PDBx:U22>
         <PDBx:U23>0.0660</PDBx:U23>
         <PDBx:U33>0.4198</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="516">
         <PDBx:U11>0.2364</PDBx:U11>
         <PDBx:U12>0.0041</PDBx:U12>
         <PDBx:U13>0.0210</PDBx:U13>
         <PDBx:U22>0.2217</PDBx:U22>
         <PDBx:U23>0.0482</PDBx:U23>
         <PDBx:U33>0.2819</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="517">
         <PDBx:U11>0.2906</PDBx:U11>
         <PDBx:U12>0.0387</PDBx:U12>
         <PDBx:U13>0.0079</PDBx:U13>
         <PDBx:U22>0.2093</PDBx:U22>
         <PDBx:U23>0.0365</PDBx:U23>
         <PDBx:U33>0.2991</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="518">
         <PDBx:U11>0.2811</PDBx:U11>
         <PDBx:U12>0.0358</PDBx:U12>
         <PDBx:U13>0.0290</PDBx:U13>
         <PDBx:U22>0.2044</PDBx:U22>
         <PDBx:U23>0.0433</PDBx:U23>
         <PDBx:U33>0.3609</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="519">
         <PDBx:U11>0.3127</PDBx:U11>
         <PDBx:U12>-0.0221</PDBx:U12>
         <PDBx:U13>0.0357</PDBx:U13>
         <PDBx:U22>0.2546</PDBx:U22>
         <PDBx:U23>0.0534</PDBx:U23>
         <PDBx:U33>0.4366</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="520">
         <PDBx:U11>0.3374</PDBx:U11>
         <PDBx:U12>0.0255</PDBx:U12>
         <PDBx:U13>-0.0040</PDBx:U13>
         <PDBx:U22>0.2922</PDBx:U22>
         <PDBx:U23>0.0570</PDBx:U23>
         <PDBx:U33>0.2645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="521">
         <PDBx:U11>0.3192</PDBx:U11>
         <PDBx:U12>0.0620</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.2826</PDBx:U22>
         <PDBx:U23>0.0215</PDBx:U23>
         <PDBx:U33>0.2870</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="522">
         <PDBx:U11>0.3006</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>0.0605</PDBx:U13>
         <PDBx:U22>0.2531</PDBx:U22>
         <PDBx:U23>-0.0205</PDBx:U23>
         <PDBx:U33>0.2942</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="523">
         <PDBx:U11>0.3591</PDBx:U11>
         <PDBx:U12>0.0114</PDBx:U12>
         <PDBx:U13>0.0461</PDBx:U13>
         <PDBx:U22>0.3849</PDBx:U22>
         <PDBx:U23>-0.0118</PDBx:U23>
         <PDBx:U33>0.2964</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="524">
         <PDBx:U11>0.2689</PDBx:U11>
         <PDBx:U12>0.0075</PDBx:U12>
         <PDBx:U13>0.0247</PDBx:U13>
         <PDBx:U22>0.1655</PDBx:U22>
         <PDBx:U23>0.0333</PDBx:U23>
         <PDBx:U33>0.2788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="525">
         <PDBx:U11>0.2619</PDBx:U11>
         <PDBx:U12>0.0070</PDBx:U12>
         <PDBx:U13>0.0380</PDBx:U13>
         <PDBx:U22>0.1945</PDBx:U22>
         <PDBx:U23>0.0528</PDBx:U23>
         <PDBx:U33>0.2967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="526">
         <PDBx:U11>0.2750</PDBx:U11>
         <PDBx:U12>-0.0256</PDBx:U12>
         <PDBx:U13>0.0231</PDBx:U13>
         <PDBx:U22>0.2633</PDBx:U22>
         <PDBx:U23>0.0228</PDBx:U23>
         <PDBx:U33>0.2590</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="527">
         <PDBx:U11>0.2930</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>0.0206</PDBx:U13>
         <PDBx:U22>0.2067</PDBx:U22>
         <PDBx:U23>0.0487</PDBx:U23>
         <PDBx:U33>0.3460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="528">
         <PDBx:U11>0.3244</PDBx:U11>
         <PDBx:U12>-0.0598</PDBx:U12>
         <PDBx:U13>0.0294</PDBx:U13>
         <PDBx:U22>0.2181</PDBx:U22>
         <PDBx:U23>0.0219</PDBx:U23>
         <PDBx:U33>0.2851</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="529">
         <PDBx:U11>0.2514</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>-0.0094</PDBx:U13>
         <PDBx:U22>0.2322</PDBx:U22>
         <PDBx:U23>0.0205</PDBx:U23>
         <PDBx:U33>0.3220</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="530">
         <PDBx:U11>0.3245</PDBx:U11>
         <PDBx:U12>0.0258</PDBx:U12>
         <PDBx:U13>0.0207</PDBx:U13>
         <PDBx:U22>0.3357</PDBx:U22>
         <PDBx:U23>0.0464</PDBx:U23>
         <PDBx:U33>0.2806</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="531">
         <PDBx:U11>0.3171</PDBx:U11>
         <PDBx:U12>0.0199</PDBx:U12>
         <PDBx:U13>-0.0392</PDBx:U13>
         <PDBx:U22>0.2733</PDBx:U22>
         <PDBx:U23>0.0831</PDBx:U23>
         <PDBx:U33>0.3688</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="532">
         <PDBx:U11>0.2797</PDBx:U11>
         <PDBx:U12>0.0172</PDBx:U12>
         <PDBx:U13>0.0190</PDBx:U13>
         <PDBx:U22>0.3010</PDBx:U22>
         <PDBx:U23>0.1174</PDBx:U23>
         <PDBx:U33>0.3326</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="533">
         <PDBx:U11>0.3366</PDBx:U11>
         <PDBx:U12>-0.0228</PDBx:U12>
         <PDBx:U13>-0.0412</PDBx:U13>
         <PDBx:U22>0.2933</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.3243</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="534">
         <PDBx:U11>0.2981</PDBx:U11>
         <PDBx:U12>0.0046</PDBx:U12>
         <PDBx:U13>-0.0100</PDBx:U13>
         <PDBx:U22>0.3013</PDBx:U22>
         <PDBx:U23>0.0879</PDBx:U23>
         <PDBx:U33>0.3175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="535">
         <PDBx:U11>0.3825</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>-0.0481</PDBx:U13>
         <PDBx:U22>0.3577</PDBx:U22>
         <PDBx:U23>0.0772</PDBx:U23>
         <PDBx:U33>0.3302</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="536">
         <PDBx:U11>0.2633</PDBx:U11>
         <PDBx:U12>0.0276</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.1715</PDBx:U22>
         <PDBx:U23>0.0269</PDBx:U23>
         <PDBx:U33>0.2640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>462</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="537">
         <PDBx:U11>0.2444</PDBx:U11>
         <PDBx:U12>0.0293</PDBx:U12>
         <PDBx:U13>0.0338</PDBx:U13>
         <PDBx:U22>0.2158</PDBx:U22>
         <PDBx:U23>0.0234</PDBx:U23>
         <PDBx:U33>0.2518</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>462</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="538">
         <PDBx:U11>0.2494</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>0.0093</PDBx:U13>
         <PDBx:U22>0.2477</PDBx:U22>
         <PDBx:U23>0.0194</PDBx:U23>
         <PDBx:U33>0.2729</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>462</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="539">
         <PDBx:U11>0.2885</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>0.0246</PDBx:U13>
         <PDBx:U22>0.1850</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.2570</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>462</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="540">
         <PDBx:U11>0.2721</PDBx:U11>
         <PDBx:U12>0.0136</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.1983</PDBx:U22>
         <PDBx:U23>0.0013</PDBx:U23>
         <PDBx:U33>0.2775</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>463</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="541">
         <PDBx:U11>0.2759</PDBx:U11>
         <PDBx:U12>-0.0145</PDBx:U12>
         <PDBx:U13>0.0151</PDBx:U13>
         <PDBx:U22>0.1681</PDBx:U22>
         <PDBx:U23>0.0034</PDBx:U23>
         <PDBx:U33>0.2433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>463</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="542">
         <PDBx:U11>0.2773</PDBx:U11>
         <PDBx:U12>0.0094</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.1845</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.2194</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>463</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="543">
         <PDBx:U11>0.2750</PDBx:U11>
         <PDBx:U12>-0.0190</PDBx:U12>
         <PDBx:U13>0.0266</PDBx:U13>
         <PDBx:U22>0.1876</PDBx:U22>
         <PDBx:U23>0.0069</PDBx:U23>
         <PDBx:U33>0.2540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>463</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="544">
         <PDBx:U11>0.2990</PDBx:U11>
         <PDBx:U12>-0.0245</PDBx:U12>
         <PDBx:U13>0.0369</PDBx:U13>
         <PDBx:U22>0.1742</PDBx:U22>
         <PDBx:U23>0.0078</PDBx:U23>
         <PDBx:U33>0.2044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>463</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="545">
         <PDBx:U11>0.3245</PDBx:U11>
         <PDBx:U12>0.0037</PDBx:U12>
         <PDBx:U13>0.0122</PDBx:U13>
         <PDBx:U22>0.1712</PDBx:U22>
         <PDBx:U23>0.0093</PDBx:U23>
         <PDBx:U33>0.2552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>463</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="546">
         <PDBx:U11>0.3361</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>0.0760</PDBx:U13>
         <PDBx:U22>0.2336</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.2648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>463</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="547">
         <PDBx:U11>0.2555</PDBx:U11>
         <PDBx:U12>-0.0007</PDBx:U12>
         <PDBx:U13>-0.0033</PDBx:U13>
         <PDBx:U22>0.1729</PDBx:U22>
         <PDBx:U23>-0.0085</PDBx:U23>
         <PDBx:U33>0.1868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="548">
         <PDBx:U11>0.2731</PDBx:U11>
         <PDBx:U12>0.0020</PDBx:U12>
         <PDBx:U13>-0.0022</PDBx:U13>
         <PDBx:U22>0.1792</PDBx:U22>
         <PDBx:U23>0.0018</PDBx:U23>
         <PDBx:U33>0.2443</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>464</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:U23>0.0265</PDBx:U23>
         <PDBx:U33>0.3847</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="566">
         <PDBx:U11>0.5923</PDBx:U11>
         <PDBx:U12>-0.0601</PDBx:U12>
         <PDBx:U13>0.0495</PDBx:U13>
         <PDBx:U22>0.3844</PDBx:U22>
         <PDBx:U23>-0.0642</PDBx:U23>
         <PDBx:U33>0.4429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="567">
         <PDBx:U11>0.5657</PDBx:U11>
         <PDBx:U12>0.0363</PDBx:U12>
         <PDBx:U13>0.0379</PDBx:U13>
         <PDBx:U22>0.7499</PDBx:U22>
         <PDBx:U23>-0.0216</PDBx:U23>
         <PDBx:U33>0.4651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="568">
         <PDBx:U11>0.8496</PDBx:U11>
         <PDBx:U12>0.1011</PDBx:U12>
         <PDBx:U13>0.1729</PDBx:U13>
         <PDBx:U22>0.8925</PDBx:U22>
         <PDBx:U23>-0.2091</PDBx:U23>
         <PDBx:U33>0.6719</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>466</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="569">
         <PDBx:U11>0.5198</PDBx:U11>
         <PDBx:U12>-0.0443</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.3188</PDBx:U22>
         <PDBx:U23>0.0101</PDBx:U23>
         <PDBx:U33>0.4013</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="570">
         <PDBx:U11>0.4268</PDBx:U11>
         <PDBx:U12>-0.0449</PDBx:U12>
         <PDBx:U13>-0.0846</PDBx:U13>
         <PDBx:U22>0.2671</PDBx:U22>
         <PDBx:U23>0.0550</PDBx:U23>
         <PDBx:U33>0.4027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="571">
         <PDBx:U11>0.4251</PDBx:U11>
         <PDBx:U12>-0.0967</PDBx:U12>
         <PDBx:U13>-0.0303</PDBx:U13>
         <PDBx:U22>0.3041</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.3563</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="572">
         <PDBx:U11>0.5512</PDBx:U11>
         <PDBx:U12>-0.0548</PDBx:U12>
         <PDBx:U13>-0.0054</PDBx:U13>
         <PDBx:U22>0.3689</PDBx:U22>
         <PDBx:U23>0.1329</PDBx:U23>
         <PDBx:U33>0.4430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="573">
         <PDBx:U11>0.5066</PDBx:U11>
         <PDBx:U12>-0.1059</PDBx:U12>
         <PDBx:U13>0.0190</PDBx:U13>
         <PDBx:U22>0.3196</PDBx:U22>
         <PDBx:U23>0.0797</PDBx:U23>
         <PDBx:U33>0.3757</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="574">
         <PDBx:U11>0.5379</PDBx:U11>
         <PDBx:U12>-0.1124</PDBx:U12>
         <PDBx:U13>-0.0605</PDBx:U13>
         <PDBx:U22>0.3878</PDBx:U22>
         <PDBx:U23>0.1078</PDBx:U23>
         <PDBx:U33>0.4299</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="575">
         <PDBx:U11>0.3747</PDBx:U11>
         <PDBx:U12>-0.1172</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.4443</PDBx:U22>
         <PDBx:U23>0.0755</PDBx:U23>
         <PDBx:U33>0.4032</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="576">
         <PDBx:U11>0.5228</PDBx:U11>
         <PDBx:U12>-0.0913</PDBx:U12>
         <PDBx:U13>-0.0745</PDBx:U13>
         <PDBx:U22>0.3584</PDBx:U22>
         <PDBx:U23>0.0584</PDBx:U23>
         <PDBx:U33>0.4751</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="577">
         <PDBx:U11>0.5194</PDBx:U11>
         <PDBx:U12>-0.0510</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.4421</PDBx:U22>
         <PDBx:U23>0.1579</PDBx:U23>
         <PDBx:U33>0.4047</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="578">
         <PDBx:U11>0.4259</PDBx:U11>
         <PDBx:U12>-0.0011</PDBx:U12>
         <PDBx:U13>-0.0603</PDBx:U13>
         <PDBx:U22>0.3440</PDBx:U22>
         <PDBx:U23>0.0846</PDBx:U23>
         <PDBx:U33>0.3187</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="579">
         <PDBx:U11>0.4246</PDBx:U11>
         <PDBx:U12>-0.0317</PDBx:U12>
         <PDBx:U13>-0.0458</PDBx:U13>
         <PDBx:U22>0.3346</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.3829</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="580">
         <PDBx:U11>0.3588</PDBx:U11>
         <PDBx:U12>0.0338</PDBx:U12>
         <PDBx:U13>-0.0200</PDBx:U13>
         <PDBx:U22>0.2596</PDBx:U22>
         <PDBx:U23>0.0168</PDBx:U23>
         <PDBx:U33>0.4583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="581">
         <PDBx:U11>0.4023</PDBx:U11>
         <PDBx:U12>0.0830</PDBx:U12>
         <PDBx:U13>-0.0601</PDBx:U13>
         <PDBx:U22>0.2805</PDBx:U22>
         <PDBx:U23>-0.0126</PDBx:U23>
         <PDBx:U33>0.5143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="582">
         <PDBx:U11>0.3474</PDBx:U11>
         <PDBx:U12>-0.0412</PDBx:U12>
         <PDBx:U13>-0.0150</PDBx:U13>
         <PDBx:U22>0.3936</PDBx:U22>
         <PDBx:U23>-0.0194</PDBx:U23>
         <PDBx:U33>0.4233</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="583">
         <PDBx:U11>0.4779</PDBx:U11>
         <PDBx:U12>0.0400</PDBx:U12>
         <PDBx:U13>-0.1026</PDBx:U13>
         <PDBx:U22>0.2197</PDBx:U22>
         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.4003</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="584">
         <PDBx:U11>0.3526</PDBx:U11>
         <PDBx:U12>0.0419</PDBx:U12>
         <PDBx:U13>-0.0882</PDBx:U13>
         <PDBx:U22>0.2757</PDBx:U22>
         <PDBx:U23>0.0547</PDBx:U23>
         <PDBx:U33>0.4828</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="585">
         <PDBx:U11>0.4667</PDBx:U11>
         <PDBx:U12>-0.0384</PDBx:U12>
         <PDBx:U13>-0.0205</PDBx:U13>
         <PDBx:U22>0.3881</PDBx:U22>
         <PDBx:U23>0.0968</PDBx:U23>
         <PDBx:U33>0.4438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="586">
         <PDBx:U11>0.5205</PDBx:U11>
         <PDBx:U12>-0.0215</PDBx:U12>
         <PDBx:U13>0.0747</PDBx:U13>
         <PDBx:U22>0.3374</PDBx:U22>
         <PDBx:U23>-0.1328</PDBx:U23>
         <PDBx:U33>0.2164</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="587">
         <PDBx:U11>0.5561</PDBx:U11>
         <PDBx:U12>-0.0576</PDBx:U12>
         <PDBx:U13>-0.0935</PDBx:U13>
         <PDBx:U22>0.2288</PDBx:U22>
         <PDBx:U23>-0.0132</PDBx:U23>
         <PDBx:U33>0.4324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="588">
         <PDBx:U11>0.6340</PDBx:U11>
         <PDBx:U12>0.2008</PDBx:U12>
         <PDBx:U13>0.0134</PDBx:U13>
         <PDBx:U22>0.3722</PDBx:U22>
         <PDBx:U23>-0.1027</PDBx:U23>
         <PDBx:U33>0.2577</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="589">
         <PDBx:U11>0.4066</PDBx:U11>
         <PDBx:U12>0.0761</PDBx:U12>
         <PDBx:U13>0.0067</PDBx:U13>
         <PDBx:U22>0.2813</PDBx:U22>
         <PDBx:U23>0.0070</PDBx:U23>
         <PDBx:U33>0.3913</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="590">
         <PDBx:U11>0.3391</PDBx:U11>
         <PDBx:U12>0.0267</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.2284</PDBx:U22>
         <PDBx:U23>0.0237</PDBx:U23>
         <PDBx:U33>0.3116</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="591">
         <PDBx:U11>0.3720</PDBx:U11>
         <PDBx:U12>-0.0063</PDBx:U12>
         <PDBx:U13>-0.0236</PDBx:U13>
         <PDBx:U22>0.2380</PDBx:U22>
         <PDBx:U23>0.0149</PDBx:U23>
         <PDBx:U33>0.3347</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="592">
         <PDBx:U11>0.3777</PDBx:U11>
         <PDBx:U12>0.0128</PDBx:U12>
         <PDBx:U13>-0.0383</PDBx:U13>
         <PDBx:U22>0.2172</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.3056</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="593">
         <PDBx:U11>0.3047</PDBx:U11>
         <PDBx:U12>0.0234</PDBx:U12>
         <PDBx:U13>0.0537</PDBx:U13>
         <PDBx:U22>0.2534</PDBx:U22>
         <PDBx:U23>0.0070</PDBx:U23>
         <PDBx:U33>0.3670</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="594">
         <PDBx:U11>0.4288</PDBx:U11>
         <PDBx:U12>0.0718</PDBx:U12>
         <PDBx:U13>0.0533</PDBx:U13>
         <PDBx:U22>0.3232</PDBx:U22>
         <PDBx:U23>0.0127</PDBx:U23>
         <PDBx:U33>0.3956</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="595">
         <PDBx:U11>0.4726</PDBx:U11>
         <PDBx:U12>0.0675</PDBx:U12>
         <PDBx:U13>0.0206</PDBx:U13>
         <PDBx:U22>0.2765</PDBx:U22>
         <PDBx:U23>-0.0150</PDBx:U23>
         <PDBx:U33>0.4354</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="596">
         <PDBx:U11>0.3685</PDBx:U11>
         <PDBx:U12>0.0130</PDBx:U12>
         <PDBx:U13>-0.0325</PDBx:U13>
         <PDBx:U22>0.2086</PDBx:U22>
         <PDBx:U23>0.0079</PDBx:U23>
         <PDBx:U33>0.2813</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="597">
         <PDBx:U11>0.3258</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>-0.0220</PDBx:U13>
         <PDBx:U22>0.2293</PDBx:U22>
         <PDBx:U23>0.0304</PDBx:U23>
         <PDBx:U33>0.2261</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="598">
         <PDBx:U11>0.2692</PDBx:U11>
         <PDBx:U12>0.0132</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.2116</PDBx:U22>
         <PDBx:U23>0.0078</PDBx:U23>
         <PDBx:U33>0.2198</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="599">
         <PDBx:U11>0.2773</PDBx:U11>
         <PDBx:U12>-0.0144</PDBx:U12>
         <PDBx:U13>0.0074</PDBx:U13>
         <PDBx:U22>0.1863</PDBx:U22>
         <PDBx:U23>0.0040</PDBx:U23>
         <PDBx:U33>0.2645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="600">
         <PDBx:U11>0.3287</PDBx:U11>
         <PDBx:U12>0.0689</PDBx:U12>
         <PDBx:U13>-0.0362</PDBx:U13>
         <PDBx:U22>0.3142</PDBx:U22>
         <PDBx:U23>-0.0350</PDBx:U23>
         <PDBx:U33>0.2445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="601">
         <PDBx:U11>0.4070</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>-0.0063</PDBx:U13>
         <PDBx:U22>0.3176</PDBx:U22>
         <PDBx:U23>-0.0661</PDBx:U23>
         <PDBx:U33>0.2605</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="602">
         <PDBx:U11>0.3247</PDBx:U11>
         <PDBx:U12>0.0131</PDBx:U12>
         <PDBx:U13>0.0232</PDBx:U13>
         <PDBx:U22>0.2831</PDBx:U22>
         <PDBx:U23>0.0388</PDBx:U23>
         <PDBx:U33>0.3439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="603">
         <PDBx:U11>0.4211</PDBx:U11>
         <PDBx:U12>-0.0650</PDBx:U12>
         <PDBx:U13>-0.0041</PDBx:U13>
         <PDBx:U22>0.3271</PDBx:U22>
         <PDBx:U23>-0.1139</PDBx:U23>
         <PDBx:U33>0.3194</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="604">
         <PDBx:U11>0.2820</PDBx:U11>
         <PDBx:U12>0.0231</PDBx:U12>
         <PDBx:U13>-0.0151</PDBx:U13>
         <PDBx:U22>0.1740</PDBx:U22>
         <PDBx:U23>-0.0075</PDBx:U23>
         <PDBx:U33>0.2377</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="605">
         <PDBx:U11>0.2545</PDBx:U11>
         <PDBx:U12>0.0013</PDBx:U12>
         <PDBx:U13>-0.0105</PDBx:U13>
         <PDBx:U22>0.1999</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.2327</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="606">
         <PDBx:U11>0.2492</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.1792</PDBx:U22>
         <PDBx:U23>0.0012</PDBx:U23>
         <PDBx:U33>0.2365</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="607">
         <PDBx:U11>0.2576</PDBx:U11>
         <PDBx:U12>-0.0303</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.1977</PDBx:U22>
         <PDBx:U23>0.0081</PDBx:U23>
         <PDBx:U33>0.2318</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="608">
         <PDBx:U11>0.2599</PDBx:U11>
         <PDBx:U12>0.0188</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.1790</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.2307</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="609">
         <PDBx:U11>0.2730</PDBx:U11>
         <PDBx:U12>0.0189</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.1900</PDBx:U22>
         <PDBx:U23>-0.0115</PDBx:U23>
         <PDBx:U33>0.2547</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="610">
         <PDBx:U11>0.2763</PDBx:U11>
         <PDBx:U12>0.0200</PDBx:U12>
         <PDBx:U13>0.0182</PDBx:U13>
         <PDBx:U22>0.2406</PDBx:U22>
         <PDBx:U23>-0.0123</PDBx:U23>
         <PDBx:U33>0.2520</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="611">
         <PDBx:U11>0.2600</PDBx:U11>
         <PDBx:U12>0.0099</PDBx:U12>
         <PDBx:U13>-0.0165</PDBx:U13>
         <PDBx:U22>0.2139</PDBx:U22>
         <PDBx:U23>-0.0196</PDBx:U23>
         <PDBx:U33>0.2725</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="612">
         <PDBx:U11>0.2988</PDBx:U11>
         <PDBx:U12>-0.0080</PDBx:U12>
         <PDBx:U13>0.0252</PDBx:U13>
         <PDBx:U22>0.2178</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.2462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="613">
         <PDBx:U11>0.3285</PDBx:U11>
         <PDBx:U12>0.0373</PDBx:U12>
         <PDBx:U13>-0.0114</PDBx:U13>
         <PDBx:U22>0.2324</PDBx:U22>
         <PDBx:U23>-0.0696</PDBx:U23>
         <PDBx:U33>0.3669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="614">
         <PDBx:U11>0.3240</PDBx:U11>
         <PDBx:U12>-0.0007</PDBx:U12>
         <PDBx:U13>0.0247</PDBx:U13>
         <PDBx:U22>0.2244</PDBx:U22>
         <PDBx:U23>-0.0175</PDBx:U23>
         <PDBx:U33>0.3186</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="615">
         <PDBx:U11>0.2201</PDBx:U11>
         <PDBx:U12>0.0126</PDBx:U12>
         <PDBx:U13>0.0149</PDBx:U13>
         <PDBx:U22>0.1785</PDBx:U22>
         <PDBx:U23>0.0137</PDBx:U23>
         <PDBx:U33>0.2492</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="616">
         <PDBx:U11>0.2158</PDBx:U11>
         <PDBx:U12>0.0113</PDBx:U12>
         <PDBx:U13>0.0088</PDBx:U13>
         <PDBx:U22>0.1785</PDBx:U22>
         <PDBx:U23>0.0103</PDBx:U23>
         <PDBx:U33>0.1903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="617">
         <PDBx:U11>0.2148</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.1742</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.2188</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="618">
         <PDBx:U11>0.2408</PDBx:U11>
         <PDBx:U12>0.0046</PDBx:U12>
         <PDBx:U13>0.0200</PDBx:U13>
         <PDBx:U22>0.1758</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.2415</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="619">
         <PDBx:U11>0.2452</PDBx:U11>
         <PDBx:U12>0.0058</PDBx:U12>
         <PDBx:U13>-0.0028</PDBx:U13>
         <PDBx:U22>0.1993</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.2036</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="620">
         <PDBx:U11>0.3058</PDBx:U11>
         <PDBx:U12>-0.0322</PDBx:U12>
         <PDBx:U13>-0.0603</PDBx:U13>
         <PDBx:U22>0.1701</PDBx:U22>
         <PDBx:U23>-0.0139</PDBx:U23>
         <PDBx:U33>0.2341</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="621">
         <PDBx:U11>0.2955</PDBx:U11>
         <PDBx:U12>0.0542</PDBx:U12>
         <PDBx:U13>-0.0209</PDBx:U13>
         <PDBx:U22>0.1978</PDBx:U22>
         <PDBx:U23>-0.0327</PDBx:U23>
         <PDBx:U33>0.2796</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="622">
         <PDBx:U11>0.3487</PDBx:U11>
         <PDBx:U12>0.0187</PDBx:U12>
         <PDBx:U13>0.0231</PDBx:U13>
         <PDBx:U22>0.1526</PDBx:U22>
         <PDBx:U23>-0.0355</PDBx:U23>
         <PDBx:U33>0.2836</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="623">
         <PDBx:U11>0.2246</PDBx:U11>
         <PDBx:U12>-0.0209</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.1773</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.2128</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="624">
         <PDBx:U11>0.2147</PDBx:U11>
         <PDBx:U12>-0.0183</PDBx:U12>
         <PDBx:U13>-0.0139</PDBx:U13>
         <PDBx:U22>0.1556</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.2310</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="625">
         <PDBx:U11>0.2105</PDBx:U11>
         <PDBx:U12>0.0010</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.1762</PDBx:U22>
         <PDBx:U23>0.0145</PDBx:U23>
         <PDBx:U33>0.2472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="626">
         <PDBx:U11>0.2459</PDBx:U11>
         <PDBx:U12>-0.0176</PDBx:U12>
         <PDBx:U13>0.0252</PDBx:U13>
         <PDBx:U22>0.1932</PDBx:U22>
         <PDBx:U23>0.0025</PDBx:U23>
         <PDBx:U33>0.2345</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="627">
         <PDBx:U11>0.2064</PDBx:U11>
         <PDBx:U12>-0.0190</PDBx:U12>
         <PDBx:U13>0.0069</PDBx:U13>
         <PDBx:U22>0.1575</PDBx:U22>
         <PDBx:U23>0.0239</PDBx:U23>
         <PDBx:U33>0.2373</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="628">
         <PDBx:U11>0.2858</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>-0.0212</PDBx:U13>
         <PDBx:U22>0.1866</PDBx:U22>
         <PDBx:U23>0.0483</PDBx:U23>
         <PDBx:U33>0.2403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="629">
         <PDBx:U11>0.2845</PDBx:U11>
         <PDBx:U12>-0.0422</PDBx:U12>
         <PDBx:U13>-0.0066</PDBx:U13>
         <PDBx:U22>0.1844</PDBx:U22>
         <PDBx:U23>-0.0167</PDBx:U23>
         <PDBx:U33>0.2459</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="630">
         <PDBx:U11>0.2637</PDBx:U11>
         <PDBx:U12>0.0325</PDBx:U12>
         <PDBx:U13>-0.0081</PDBx:U13>
         <PDBx:U22>0.2014</PDBx:U22>
         <PDBx:U23>0.0525</PDBx:U23>
         <PDBx:U33>0.2564</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.0014</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0359</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="647">
         <PDBx:U11>0.2755</PDBx:U11>
         <PDBx:U12>-0.0097</PDBx:U12>
         <PDBx:U13>0.0413</PDBx:U13>
         <PDBx:U22>0.1932</PDBx:U22>
         <PDBx:U23>0.0400</PDBx:U23>
         <PDBx:U33>0.2865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="648">
         <PDBx:U11>0.2451</PDBx:U11>
         <PDBx:U12>0.0066</PDBx:U12>
         <PDBx:U13>0.0226</PDBx:U13>
         <PDBx:U22>0.1670</PDBx:U22>
         <PDBx:U23>-0.0084</PDBx:U23>
         <PDBx:U33>0.2184</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="649">
         <PDBx:U11>0.2550</PDBx:U11>
         <PDBx:U12>-0.0236</PDBx:U12>
         <PDBx:U13>-0.0095</PDBx:U13>
         <PDBx:U22>0.1985</PDBx:U22>
         <PDBx:U23>0.0140</PDBx:U23>
         <PDBx:U33>0.2183</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="650">
         <PDBx:U11>0.2311</PDBx:U11>
         <PDBx:U12>-0.0453</PDBx:U12>
         <PDBx:U13>-0.0039</PDBx:U13>
         <PDBx:U22>0.2074</PDBx:U22>
         <PDBx:U23>0.0305</PDBx:U23>
         <PDBx:U33>0.2653</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="651">
         <PDBx:U11>0.2931</PDBx:U11>
         <PDBx:U12>-0.0235</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.1511</PDBx:U22>
         <PDBx:U23>-0.0407</PDBx:U23>
         <PDBx:U33>0.2875</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="652">
         <PDBx:U11>0.3081</PDBx:U11>
         <PDBx:U12>0.0248</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.1580</PDBx:U22>
         <PDBx:U23>-0.0102</PDBx:U23>
         <PDBx:U33>0.2436</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="653">
         <PDBx:U11>0.3043</PDBx:U11>
         <PDBx:U12>0.0046</PDBx:U12>
         <PDBx:U13>0.0252</PDBx:U13>
         <PDBx:U22>0.1798</PDBx:U22>
         <PDBx:U23>0.0093</PDBx:U23>
         <PDBx:U33>0.3104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="654">
         <PDBx:U11>0.3412</PDBx:U11>
         <PDBx:U12>-0.0003</PDBx:U12>
         <PDBx:U13>-0.0134</PDBx:U13>
         <PDBx:U22>0.1372</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.2495</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="655">
         <PDBx:U11>0.3138</PDBx:U11>
         <PDBx:U12>0.0166</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.1985</PDBx:U22>
         <PDBx:U23>0.0189</PDBx:U23>
         <PDBx:U33>0.2799</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="656">
         <PDBx:U11>0.3875</PDBx:U11>
         <PDBx:U12>-0.0153</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.2111</PDBx:U22>
         <PDBx:U23>0.0234</PDBx:U23>
         <PDBx:U33>0.2610</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="657">
         <PDBx:U11>0.3366</PDBx:U11>
         <PDBx:U12>0.0491</PDBx:U12>
         <PDBx:U13>0.0399</PDBx:U13>
         <PDBx:U22>0.2044</PDBx:U22>
         <PDBx:U23>0.0228</PDBx:U23>
         <PDBx:U33>0.2830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="658">
         <PDBx:U11>0.3677</PDBx:U11>
         <PDBx:U12>0.0052</PDBx:U12>
         <PDBx:U13>0.0574</PDBx:U13>
         <PDBx:U22>0.2241</PDBx:U22>
         <PDBx:U23>0.0031</PDBx:U23>
         <PDBx:U33>0.3367</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="659">
         <PDBx:U11>0.2448</PDBx:U11>
         <PDBx:U12>-0.0090</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.1629</PDBx:U22>
         <PDBx:U23>0.0290</PDBx:U23>
         <PDBx:U33>0.1612</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="660">
         <PDBx:U11>0.2836</PDBx:U11>
         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>0.0142</PDBx:U13>
         <PDBx:U22>0.1421</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.1501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="661">
         <PDBx:U11>0.2386</PDBx:U11>
         <PDBx:U12>-0.0050</PDBx:U12>
         <PDBx:U13>0.0112</PDBx:U13>
         <PDBx:U22>0.1900</PDBx:U22>
         <PDBx:U23>-0.0188</PDBx:U23>
         <PDBx:U33>0.2001</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="662">
         <PDBx:U11>0.2495</PDBx:U11>
         <PDBx:U12>-0.0100</PDBx:U12>
         <PDBx:U13>0.0089</PDBx:U13>
         <PDBx:U22>0.1974</PDBx:U22>
         <PDBx:U23>0.0032</PDBx:U23>
         <PDBx:U33>0.1942</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="663">
         <PDBx:U11>0.2341</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>0.0189</PDBx:U13>
         <PDBx:U22>0.1646</PDBx:U22>
         <PDBx:U23>-0.0294</PDBx:U23>
         <PDBx:U33>0.1765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
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         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0327</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0150</PDBx:U13>
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         <PDBx:U23>-0.0092</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.1992</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.2041</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U13>-0.0150</PDBx:U13>
         <PDBx:U22>0.1864</PDBx:U22>
         <PDBx:U23>0.0200</PDBx:U23>
         <PDBx:U33>0.2254</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>-0.0184</PDBx:U13>
         <PDBx:U22>0.1935</PDBx:U22>
         <PDBx:U23>0.0370</PDBx:U23>
         <PDBx:U33>0.1966</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.1559</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.2079</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="687">
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         <PDBx:U12>0.0120</PDBx:U12>
         <PDBx:U13>-0.0023</PDBx:U13>
         <PDBx:U22>0.1863</PDBx:U22>
         <PDBx:U23>-0.0151</PDBx:U23>
         <PDBx:U33>0.1906</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="688">
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         <PDBx:U12>0.1260</PDBx:U12>
         <PDBx:U13>-0.1271</PDBx:U13>
         <PDBx:U22>0.2816</PDBx:U22>
         <PDBx:U23>-0.0332</PDBx:U23>
         <PDBx:U33>0.2235</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="689">
         <PDBx:U11>0.3660</PDBx:U11>
         <PDBx:U12>-0.0155</PDBx:U12>
         <PDBx:U13>-0.0813</PDBx:U13>
         <PDBx:U22>0.2600</PDBx:U22>
         <PDBx:U23>0.0247</PDBx:U23>
         <PDBx:U33>0.3921</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="690">
         <PDBx:U11>0.2044</PDBx:U11>
         <PDBx:U12>0.0082</PDBx:U12>
         <PDBx:U13>-0.0207</PDBx:U13>
         <PDBx:U22>0.1525</PDBx:U22>
         <PDBx:U23>0.0013</PDBx:U23>
         <PDBx:U33>0.2107</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="691">
         <PDBx:U11>0.1974</PDBx:U11>
         <PDBx:U12>0.0014</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.1551</PDBx:U22>
         <PDBx:U23>0.0106</PDBx:U23>
         <PDBx:U33>0.1829</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.1668</PDBx:U22>
         <PDBx:U23>0.0045</PDBx:U23>
         <PDBx:U33>0.1925</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0131</PDBx:U13>
         <PDBx:U22>0.1917</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.1638</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="694">
         <PDBx:U11>0.1829</PDBx:U11>
         <PDBx:U12>0.0120</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.1637</PDBx:U22>
         <PDBx:U23>0.0131</PDBx:U23>
         <PDBx:U33>0.2116</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="695">
         <PDBx:U11>0.1779</PDBx:U11>
         <PDBx:U12>0.0207</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.1824</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.1661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="696">
         <PDBx:U11>0.2263</PDBx:U11>
         <PDBx:U12>0.0185</PDBx:U12>
         <PDBx:U13>-0.0290</PDBx:U13>
         <PDBx:U22>0.2129</PDBx:U22>
         <PDBx:U23>0.0286</PDBx:U23>
         <PDBx:U33>0.1762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="697">
         <PDBx:U11>0.2002</PDBx:U11>
         <PDBx:U12>0.0261</PDBx:U12>
         <PDBx:U13>0.0447</PDBx:U13>
         <PDBx:U22>0.1907</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.2139</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="698">
         <PDBx:U11>0.1899</PDBx:U11>
         <PDBx:U12>-0.0082</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.1644</PDBx:U22>
         <PDBx:U23>0.0212</PDBx:U23>
         <PDBx:U33>0.1831</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="699">
         <PDBx:U11>0.1629</PDBx:U11>
         <PDBx:U12>-0.0102</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.1966</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1802</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="700">
         <PDBx:U11>0.2332</PDBx:U11>
         <PDBx:U12>0.0479</PDBx:U12>
         <PDBx:U13>0.0089</PDBx:U13>
         <PDBx:U22>0.1985</PDBx:U22>
         <PDBx:U23>0.0098</PDBx:U23>
         <PDBx:U33>0.1872</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="701">
         <PDBx:U11>0.2111</PDBx:U11>
         <PDBx:U12>0.0007</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.1860</PDBx:U22>
         <PDBx:U23>0.0126</PDBx:U23>
         <PDBx:U33>0.1942</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="702">
         <PDBx:U11>0.1975</PDBx:U11>
         <PDBx:U12>-0.0352</PDBx:U12>
         <PDBx:U13>-0.0147</PDBx:U13>
         <PDBx:U22>0.1806</PDBx:U22>
         <PDBx:U23>-0.0159</PDBx:U23>
         <PDBx:U33>0.1683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="703">
         <PDBx:U11>0.1733</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.1961</PDBx:U22>
         <PDBx:U23>0.0162</PDBx:U23>
         <PDBx:U33>0.2090</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="704">
         <PDBx:U11>0.2514</PDBx:U11>
         <PDBx:U12>0.0118</PDBx:U12>
         <PDBx:U13>0.0241</PDBx:U13>
         <PDBx:U22>0.1680</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.2390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="705">
         <PDBx:U11>0.2780</PDBx:U11>
         <PDBx:U12>-0.0270</PDBx:U12>
         <PDBx:U13>-0.0128</PDBx:U13>
         <PDBx:U22>0.2513</PDBx:U22>
         <PDBx:U23>0.0219</PDBx:U23>
         <PDBx:U33>0.2130</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="706">
         <PDBx:U11>0.2056</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>0.0084</PDBx:U13>
         <PDBx:U22>0.1645</PDBx:U22>
         <PDBx:U23>-0.0430</PDBx:U23>
         <PDBx:U33>0.2129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="707">
         <PDBx:U11>0.2427</PDBx:U11>
         <PDBx:U12>0.0343</PDBx:U12>
         <PDBx:U13>0.0104</PDBx:U13>
         <PDBx:U22>0.1822</PDBx:U22>
         <PDBx:U23>-0.0218</PDBx:U23>
         <PDBx:U33>0.2007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="708">
         <PDBx:U11>0.2352</PDBx:U11>
         <PDBx:U12>0.0232</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>0.1987</PDBx:U22>
         <PDBx:U23>0.0186</PDBx:U23>
         <PDBx:U33>0.2115</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="709">
         <PDBx:U11>0.2387</PDBx:U11>
         <PDBx:U12>0.0127</PDBx:U12>
         <PDBx:U13>0.0194</PDBx:U13>
         <PDBx:U22>0.2283</PDBx:U22>
         <PDBx:U23>-0.0153</PDBx:U23>
         <PDBx:U33>0.2264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="710">
         <PDBx:U11>0.2726</PDBx:U11>
         <PDBx:U12>0.0650</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.1975</PDBx:U22>
         <PDBx:U23>-0.0125</PDBx:U23>
         <PDBx:U33>0.2298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="711">
         <PDBx:U11>0.3626</PDBx:U11>
         <PDBx:U12>-0.0146</PDBx:U12>
         <PDBx:U13>-0.1141</PDBx:U13>
         <PDBx:U22>0.3087</PDBx:U22>
         <PDBx:U23>0.0121</PDBx:U23>
         <PDBx:U33>0.3439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="712">
         <PDBx:U11>0.4523</PDBx:U11>
         <PDBx:U12>-0.0877</PDBx:U12>
         <PDBx:U13>-0.0932</PDBx:U13>
         <PDBx:U22>0.5083</PDBx:U22>
         <PDBx:U23>-0.0341</PDBx:U23>
         <PDBx:U33>0.4256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="713">
         <PDBx:U11>0.5252</PDBx:U11>
         <PDBx:U12>0.0624</PDBx:U12>
         <PDBx:U13>-0.1107</PDBx:U13>
         <PDBx:U22>0.4019</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.4031</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="714">
         <PDBx:U11>0.2278</PDBx:U11>
         <PDBx:U12>0.0047</PDBx:U12>
         <PDBx:U13>-0.0100</PDBx:U13>
         <PDBx:U22>0.1725</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.1903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="715">
         <PDBx:U11>0.2563</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.1934</PDBx:U22>
         <PDBx:U23>0.0153</PDBx:U23>
         <PDBx:U33>0.2019</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="716">
         <PDBx:U11>0.2597</PDBx:U11>
         <PDBx:U12>0.0366</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.1823</PDBx:U22>
         <PDBx:U23>-0.0112</PDBx:U23>
         <PDBx:U33>0.1899</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="717">
         <PDBx:U11>0.2491</PDBx:U11>
         <PDBx:U12>-0.0267</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.2090</PDBx:U22>
         <PDBx:U23>-0.0316</PDBx:U23>
         <PDBx:U33>0.1876</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="718">
         <PDBx:U11>0.2259</PDBx:U11>
         <PDBx:U12>-0.0363</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.2109</PDBx:U22>
         <PDBx:U23>-0.0336</PDBx:U23>
         <PDBx:U33>0.2151</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="719">
         <PDBx:U11>0.2573</PDBx:U11>
         <PDBx:U12>-0.0440</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.1855</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.2116</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="720">
         <PDBx:U11>0.2846</PDBx:U11>
         <PDBx:U12>-0.0584</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.2511</PDBx:U22>
         <PDBx:U23>-0.0512</PDBx:U23>
         <PDBx:U33>0.2079</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="721">
         <PDBx:U11>0.2571</PDBx:U11>
         <PDBx:U12>-0.0336</PDBx:U12>
         <PDBx:U13>-0.0411</PDBx:U13>
         <PDBx:U22>0.2199</PDBx:U22>
         <PDBx:U23>0.0207</PDBx:U23>
         <PDBx:U33>0.2259</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="722">
         <PDBx:U11>0.2828</PDBx:U11>
         <PDBx:U12>-0.0469</PDBx:U12>
         <PDBx:U13>-0.0168</PDBx:U13>
         <PDBx:U22>0.2822</PDBx:U22>
         <PDBx:U23>-0.0183</PDBx:U23>
         <PDBx:U33>0.2038</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="723">
         <PDBx:U11>0.2685</PDBx:U11>
         <PDBx:U12>-0.0096</PDBx:U12>
         <PDBx:U13>-0.0366</PDBx:U13>
         <PDBx:U22>0.2335</PDBx:U22>
         <PDBx:U23>0.0378</PDBx:U23>
         <PDBx:U33>0.2351</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="724">
         <PDBx:U11>0.3093</PDBx:U11>
         <PDBx:U12>-0.0772</PDBx:U12>
         <PDBx:U13>-0.0330</PDBx:U13>
         <PDBx:U22>0.2903</PDBx:U22>
         <PDBx:U23>0.0178</PDBx:U23>
         <PDBx:U33>0.1830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="725">
         <PDBx:U11>0.3440</PDBx:U11>
         <PDBx:U12>-0.1297</PDBx:U12>
         <PDBx:U13>-0.0927</PDBx:U13>
         <PDBx:U22>0.4485</PDBx:U22>
         <PDBx:U23>0.0724</PDBx:U23>
         <PDBx:U33>0.2851</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="726">
         <PDBx:U11>0.2378</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>-0.0158</PDBx:U13>
         <PDBx:U22>0.1683</PDBx:U22>
         <PDBx:U23>0.0024</PDBx:U23>
         <PDBx:U33>0.1899</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="727">
         <PDBx:U11>0.2382</PDBx:U11>
         <PDBx:U12>-0.0099</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1394</PDBx:U22>
         <PDBx:U23>-0.0163</PDBx:U23>
         <PDBx:U33>0.1827</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="728">
         <PDBx:U11>0.2121</PDBx:U11>
         <PDBx:U12>0.0290</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.1740</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.1780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="729">
         <PDBx:U11>0.2001</PDBx:U11>
         <PDBx:U12>-0.0153</PDBx:U12>
         <PDBx:U13>-0.0085</PDBx:U13>
         <PDBx:U22>0.1750</PDBx:U22>
         <PDBx:U23>0.0124</PDBx:U23>
         <PDBx:U33>0.1912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="730">
         <PDBx:U11>0.1922</PDBx:U11>
         <PDBx:U12>0.0100</PDBx:U12>
         <PDBx:U13>-0.0108</PDBx:U13>
         <PDBx:U22>0.1748</PDBx:U22>
         <PDBx:U23>-0.0176</PDBx:U23>
         <PDBx:U33>0.1645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="731">
         <PDBx:U11>0.1951</PDBx:U11>
         <PDBx:U12>0.0386</PDBx:U12>
         <PDBx:U13>-0.0147</PDBx:U13>
         <PDBx:U22>0.1852</PDBx:U22>
         <PDBx:U23>-0.0143</PDBx:U23>
         <PDBx:U33>0.1636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="732">
         <PDBx:U11>0.2152</PDBx:U11>
         <PDBx:U12>0.0100</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.2076</PDBx:U22>
         <PDBx:U23>-0.0215</PDBx:U23>
         <PDBx:U33>0.1548</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="733">
         <PDBx:U11>0.2099</PDBx:U11>
         <PDBx:U12>0.0381</PDBx:U12>
         <PDBx:U13>-0.0049</PDBx:U13>
         <PDBx:U22>0.1709</PDBx:U22>
         <PDBx:U23>0.0218</PDBx:U23>
         <PDBx:U33>0.1897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="734">
         <PDBx:U11>0.1830</PDBx:U11>
         <PDBx:U12>0.0068</PDBx:U12>
         <PDBx:U13>0.0134</PDBx:U13>
         <PDBx:U22>0.1919</PDBx:U22>
         <PDBx:U23>-0.0212</PDBx:U23>
         <PDBx:U33>0.1918</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="735">
         <PDBx:U11>0.1964</PDBx:U11>
         <PDBx:U12>-0.0174</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.2309</PDBx:U22>
         <PDBx:U23>0.0093</PDBx:U23>
         <PDBx:U33>0.2017</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="736">
         <PDBx:U11>0.2473</PDBx:U11>
         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>0.0274</PDBx:U13>
         <PDBx:U22>0.2266</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.2230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="737">
         <PDBx:U11>0.2518</PDBx:U11>
         <PDBx:U12>-0.0483</PDBx:U12>
         <PDBx:U13>0.0433</PDBx:U13>
         <PDBx:U22>0.2997</PDBx:U22>
         <PDBx:U23>-0.0477</PDBx:U23>
         <PDBx:U33>0.2329</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="738">
         <PDBx:U11>0.2128</PDBx:U11>
         <PDBx:U12>0.0046</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.2019</PDBx:U22>
         <PDBx:U23>-0.0189</PDBx:U23>
         <PDBx:U33>0.1770</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="739">
         <PDBx:U11>0.2005</PDBx:U11>
         <PDBx:U12>0.0225</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.2189</PDBx:U22>
         <PDBx:U23>-0.0176</PDBx:U23>
         <PDBx:U33>0.1581</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="740">
         <PDBx:U11>0.2311</PDBx:U11>
         <PDBx:U12>0.0032</PDBx:U12>
         <PDBx:U13>-0.0436</PDBx:U13>
         <PDBx:U22>0.2252</PDBx:U22>
         <PDBx:U23>-0.0118</PDBx:U23>
         <PDBx:U33>0.2098</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="741">
         <PDBx:U11>0.2362</PDBx:U11>
         <PDBx:U12>0.0023</PDBx:U12>
         <PDBx:U13>-0.0085</PDBx:U13>
         <PDBx:U22>0.2625</PDBx:U22>
         <PDBx:U23>-0.0186</PDBx:U23>
         <PDBx:U33>0.2139</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="742">
         <PDBx:U11>0.2776</PDBx:U11>
         <PDBx:U12>0.0592</PDBx:U12>
         <PDBx:U13>-0.0464</PDBx:U13>
         <PDBx:U22>0.2821</PDBx:U22>
         <PDBx:U23>-0.0344</PDBx:U23>
         <PDBx:U33>0.2264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="743">
         <PDBx:U11>0.2986</PDBx:U11>
         <PDBx:U12>0.0950</PDBx:U12>
         <PDBx:U13>-0.0355</PDBx:U13>
         <PDBx:U22>0.3153</PDBx:U22>
         <PDBx:U23>-0.0170</PDBx:U23>
         <PDBx:U33>0.3112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="744">
         <PDBx:U11>0.2426</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>-0.0271</PDBx:U13>
         <PDBx:U22>0.2447</PDBx:U22>
         <PDBx:U23>-0.0269</PDBx:U23>
         <PDBx:U33>0.2499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="745">
         <PDBx:U11>0.2342</PDBx:U11>
         <PDBx:U12>0.0232</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.2277</PDBx:U22>
         <PDBx:U23>-0.0115</PDBx:U23>
         <PDBx:U33>0.1615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="746">
         <PDBx:U11>0.2585</PDBx:U11>
         <PDBx:U12>-0.0003</PDBx:U12>
         <PDBx:U13>-0.0137</PDBx:U13>
         <PDBx:U22>0.2167</PDBx:U22>
         <PDBx:U23>-0.0237</PDBx:U23>
         <PDBx:U33>0.1780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="747">
         <PDBx:U11>0.2288</PDBx:U11>
         <PDBx:U12>0.0017</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.2104</PDBx:U22>
         <PDBx:U23>-0.0147</PDBx:U23>
         <PDBx:U33>0.1890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="748">
         <PDBx:U11>0.2450</PDBx:U11>
         <PDBx:U12>-0.0055</PDBx:U12>
         <PDBx:U13>0.0269</PDBx:U13>
         <PDBx:U22>0.2341</PDBx:U22>
         <PDBx:U23>0.0019</PDBx:U23>
         <PDBx:U33>0.2120</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="749">
         <PDBx:U11>0.3209</PDBx:U11>
         <PDBx:U12>0.0138</PDBx:U12>
         <PDBx:U13>-0.0405</PDBx:U13>
         <PDBx:U22>0.2071</PDBx:U22>
         <PDBx:U23>0.0157</PDBx:U23>
         <PDBx:U33>0.2303</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="750">
         <PDBx:U11>0.3524</PDBx:U11>
         <PDBx:U12>0.0621</PDBx:U12>
         <PDBx:U13>-0.0366</PDBx:U13>
         <PDBx:U22>0.2402</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.2081</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="751">
         <PDBx:U11>0.4346</PDBx:U11>
         <PDBx:U12>0.0039</PDBx:U12>
         <PDBx:U13>0.0154</PDBx:U13>
         <PDBx:U22>0.3447</PDBx:U22>
         <PDBx:U23>0.0044</PDBx:U23>
         <PDBx:U33>0.5135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="752">
         <PDBx:U11>0.4514</PDBx:U11>
         <PDBx:U12>0.1430</PDBx:U12>
         <PDBx:U13>-0.0469</PDBx:U13>
         <PDBx:U22>0.3984</PDBx:U22>
         <PDBx:U23>-0.0347</PDBx:U23>
         <PDBx:U33>0.3280</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="753">
         <PDBx:U11>0.4991</PDBx:U11>
         <PDBx:U12>0.1073</PDBx:U12>
         <PDBx:U13>0.0204</PDBx:U13>
         <PDBx:U22>0.4352</PDBx:U22>
         <PDBx:U23>0.0023</PDBx:U23>
         <PDBx:U33>0.7724</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="754">
         <PDBx:U11>0.2407</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>-0.0057</PDBx:U13>
         <PDBx:U22>0.2023</PDBx:U22>
         <PDBx:U23>0.0034</PDBx:U23>
         <PDBx:U33>0.1687</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="755">
         <PDBx:U11>0.2235</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>-0.0185</PDBx:U13>
         <PDBx:U22>0.2187</PDBx:U22>
         <PDBx:U23>0.0259</PDBx:U23>
         <PDBx:U33>0.2140</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="756">
         <PDBx:U11>0.2759</PDBx:U11>
         <PDBx:U12>-0.0145</PDBx:U12>
         <PDBx:U13>-0.0244</PDBx:U13>
         <PDBx:U22>0.2059</PDBx:U22>
         <PDBx:U23>0.0064</PDBx:U23>
         <PDBx:U33>0.2070</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="757">
         <PDBx:U11>0.1983</PDBx:U11>
         <PDBx:U12>-0.0120</PDBx:U12>
         <PDBx:U13>0.0166</PDBx:U13>
         <PDBx:U22>0.2057</PDBx:U22>
         <PDBx:U23>0.0174</PDBx:U23>
         <PDBx:U33>0.2221</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="758">
         <PDBx:U11>0.2447</PDBx:U11>
         <PDBx:U12>-0.0450</PDBx:U12>
         <PDBx:U13>-0.0019</PDBx:U13>
         <PDBx:U22>0.2814</PDBx:U22>
         <PDBx:U23>0.0814</PDBx:U23>
         <PDBx:U33>0.2469</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="759">
         <PDBx:U11>0.2483</PDBx:U11>
         <PDBx:U12>0.0105</PDBx:U12>
         <PDBx:U13>-0.0166</PDBx:U13>
         <PDBx:U22>0.2036</PDBx:U22>
         <PDBx:U23>-0.0090</PDBx:U23>
         <PDBx:U33>0.1849</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="760">
         <PDBx:U11>0.2153</PDBx:U11>
         <PDBx:U12>0.0174</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.1801</PDBx:U22>
         <PDBx:U23>-0.0427</PDBx:U23>
         <PDBx:U33>0.2119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="761">
         <PDBx:U11>0.2205</PDBx:U11>
         <PDBx:U12>0.0219</PDBx:U12>
         <PDBx:U13>0.0147</PDBx:U13>
         <PDBx:U22>0.1722</PDBx:U22>
         <PDBx:U23>-0.0226</PDBx:U23>
         <PDBx:U33>0.1698</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="762">
         <PDBx:U11>0.2427</PDBx:U11>
         <PDBx:U12>0.0184</PDBx:U12>
         <PDBx:U13>-0.0078</PDBx:U13>
         <PDBx:U22>0.1935</PDBx:U22>
         <PDBx:U23>-0.0120</PDBx:U23>
         <PDBx:U33>0.2199</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="763">
         <PDBx:U11>0.2843</PDBx:U11>
         <PDBx:U12>0.0254</PDBx:U12>
         <PDBx:U13>-0.0043</PDBx:U13>
         <PDBx:U22>0.1788</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1846</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="764">
         <PDBx:U11>0.2497</PDBx:U11>
         <PDBx:U12>0.0111</PDBx:U12>
         <PDBx:U13>0.0216</PDBx:U13>
         <PDBx:U22>0.1864</PDBx:U22>
         <PDBx:U23>0.0098</PDBx:U23>
         <PDBx:U33>0.2114</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="765">
         <PDBx:U11>0.2747</PDBx:U11>
         <PDBx:U12>0.0778</PDBx:U12>
         <PDBx:U13>0.0305</PDBx:U13>
         <PDBx:U22>0.2323</PDBx:U22>
         <PDBx:U23>0.0172</PDBx:U23>
         <PDBx:U33>0.2206</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="766">
         <PDBx:U11>0.3026</PDBx:U11>
         <PDBx:U12>0.0653</PDBx:U12>
         <PDBx:U13>0.0093</PDBx:U13>
         <PDBx:U22>0.2209</PDBx:U22>
         <PDBx:U23>0.0114</PDBx:U23>
         <PDBx:U33>0.2317</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="767">
         <PDBx:U11>0.3108</PDBx:U11>
         <PDBx:U12>0.0086</PDBx:U12>
         <PDBx:U13>-0.0033</PDBx:U13>
         <PDBx:U22>0.2085</PDBx:U22>
         <PDBx:U23>0.0177</PDBx:U23>
         <PDBx:U33>0.2465</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="768">
         <PDBx:U11>0.3583</PDBx:U11>
         <PDBx:U12>0.0128</PDBx:U12>
         <PDBx:U13>-0.0077</PDBx:U13>
         <PDBx:U22>0.2143</PDBx:U22>
         <PDBx:U23>0.0212</PDBx:U23>
         <PDBx:U33>0.2562</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="769">
         <PDBx:U11>0.4064</PDBx:U11>
         <PDBx:U12>0.0135</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.2505</PDBx:U22>
         <PDBx:U23>0.0120</PDBx:U23>
         <PDBx:U33>0.2428</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="770">
         <PDBx:U11>0.2297</PDBx:U11>
         <PDBx:U12>0.0212</PDBx:U12>
         <PDBx:U13>0.0336</PDBx:U13>
         <PDBx:U22>0.1813</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.1675</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="771">
         <PDBx:U11>0.2279</PDBx:U11>
         <PDBx:U12>-0.0035</PDBx:U12>
         <PDBx:U13>0.0197</PDBx:U13>
         <PDBx:U22>0.2086</PDBx:U22>
         <PDBx:U23>-0.0130</PDBx:U23>
         <PDBx:U33>0.1571</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="772">
         <PDBx:U11>0.2155</PDBx:U11>
         <PDBx:U12>-0.0204</PDBx:U12>
         <PDBx:U13>0.0056</PDBx:U13>
         <PDBx:U22>0.1957</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.1748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="773">
         <PDBx:U11>0.2296</PDBx:U11>
         <PDBx:U12>0.0144</PDBx:U12>
         <PDBx:U13>-0.0286</PDBx:U13>
         <PDBx:U22>0.2057</PDBx:U22>
         <PDBx:U23>0.0043</PDBx:U23>
         <PDBx:U33>0.1842</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="774">
         <PDBx:U11>0.2701</PDBx:U11>
         <PDBx:U12>-0.0203</PDBx:U12>
         <PDBx:U13>0.0084</PDBx:U13>
         <PDBx:U22>0.1731</PDBx:U22>
         <PDBx:U23>0.0029</PDBx:U23>
         <PDBx:U33>0.1556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="775">
         <PDBx:U11>0.2385</PDBx:U11>
         <PDBx:U12>0.0169</PDBx:U12>
         <PDBx:U13>0.0188</PDBx:U13>
         <PDBx:U22>0.1974</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="776">
         <PDBx:U11>0.3054</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0292</PDBx:U13>
         <PDBx:U22>0.2098</PDBx:U22>
         <PDBx:U23>-0.0092</PDBx:U23>
         <PDBx:U33>0.2112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="777">
         <PDBx:U11>0.2638</PDBx:U11>
         <PDBx:U12>-0.0061</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.2144</PDBx:U22>
         <PDBx:U23>-0.0177</PDBx:U23>
         <PDBx:U33>0.1897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="778">
         <PDBx:U11>0.2567</PDBx:U11>
         <PDBx:U12>-0.0278</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.2158</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.2145</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="779">
         <PDBx:U11>0.3405</PDBx:U11>
         <PDBx:U12>-0.0281</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.2340</PDBx:U22>
         <PDBx:U23>0.0071</PDBx:U23>
         <PDBx:U33>0.1896</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="780">
         <PDBx:U11>0.2422</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>0.0059</PDBx:U13>
         <PDBx:U22>0.1710</PDBx:U22>
         <PDBx:U23>0.0052</PDBx:U23>
         <PDBx:U33>0.1582</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="781">
         <PDBx:U11>0.2042</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>-0.0064</PDBx:U13>
         <PDBx:U22>0.1984</PDBx:U22>
         <PDBx:U23>0.0166</PDBx:U23>
         <PDBx:U33>0.1542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="782">
         <PDBx:U11>0.2172</PDBx:U11>
         <PDBx:U12>0.0036</PDBx:U12>
         <PDBx:U13>-0.0190</PDBx:U13>
         <PDBx:U22>0.1934</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.1782</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="783">
         <PDBx:U11>0.2219</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>-0.0059</PDBx:U13>
         <PDBx:U22>0.2043</PDBx:U22>
         <PDBx:U23>0.0166</PDBx:U23>
         <PDBx:U33>0.1837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="784">
         <PDBx:U11>0.1933</PDBx:U11>
         <PDBx:U12>-0.0191</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.1916</PDBx:U22>
         <PDBx:U23>-0.0162</PDBx:U23>
         <PDBx:U33>0.1704</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="785">
         <PDBx:U11>0.2101</PDBx:U11>
         <PDBx:U12>-0.0135</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.1693</PDBx:U22>
         <PDBx:U23>-0.0135</PDBx:U23>
         <PDBx:U33>0.1714</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="786">
         <PDBx:U11>0.2186</PDBx:U11>
         <PDBx:U12>0.0164</PDBx:U12>
         <PDBx:U13>-0.0078</PDBx:U13>
         <PDBx:U22>0.1916</PDBx:U22>
         <PDBx:U23>0.0265</PDBx:U23>
         <PDBx:U33>0.1620</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="787">
         <PDBx:U11>0.2127</PDBx:U11>
         <PDBx:U12>0.0116</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.1792</PDBx:U22>
         <PDBx:U23>0.0191</PDBx:U23>
         <PDBx:U33>0.1948</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="788">
         <PDBx:U11>0.2199</PDBx:U11>
         <PDBx:U12>0.0036</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.2011</PDBx:U22>
         <PDBx:U23>0.0083</PDBx:U23>
         <PDBx:U33>0.2414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="789">
         <PDBx:U11>0.2671</PDBx:U11>
         <PDBx:U12>0.0166</PDBx:U12>
         <PDBx:U13>-0.0180</PDBx:U13>
         <PDBx:U22>0.2026</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.1636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="790">
         <PDBx:U11>0.2467</PDBx:U11>
         <PDBx:U12>0.0076</PDBx:U12>
         <PDBx:U13>-0.0156</PDBx:U13>
         <PDBx:U22>0.1819</PDBx:U22>
         <PDBx:U23>-0.0180</PDBx:U23>
         <PDBx:U33>0.1937</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="791">
         <PDBx:U11>0.2442</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>0.0211</PDBx:U13>
         <PDBx:U22>0.2194</PDBx:U22>
         <PDBx:U23>-0.0113</PDBx:U23>
         <PDBx:U33>0.1786</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="792">
         <PDBx:U11>0.2367</PDBx:U11>
         <PDBx:U12>0.0140</PDBx:U12>
         <PDBx:U13>-0.0301</PDBx:U13>
         <PDBx:U22>0.2298</PDBx:U22>
         <PDBx:U23>0.0111</PDBx:U23>
         <PDBx:U33>0.1921</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="793">
         <PDBx:U11>0.2499</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>0.0067</PDBx:U13>
         <PDBx:U22>0.2347</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.1760</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="794">
         <PDBx:U11>0.2807</PDBx:U11>
         <PDBx:U12>0.0041</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.1896</PDBx:U22>
         <PDBx:U23>-0.0252</PDBx:U23>
         <PDBx:U33>0.1857</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="795">
         <PDBx:U11>0.2315</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.1981</PDBx:U22>
         <PDBx:U23>-0.0114</PDBx:U23>
         <PDBx:U33>0.1916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="796">
         <PDBx:U11>0.2063</PDBx:U11>
         <PDBx:U12>-0.0126</PDBx:U12>
         <PDBx:U13>0.0116</PDBx:U13>
         <PDBx:U22>0.2084</PDBx:U22>
         <PDBx:U23>0.0068</PDBx:U23>
         <PDBx:U33>0.1753</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="797">
         <PDBx:U11>0.2019</PDBx:U11>
         <PDBx:U12>-0.0141</PDBx:U12>
         <PDBx:U13>-0.0138</PDBx:U13>
         <PDBx:U22>0.2038</PDBx:U22>
         <PDBx:U23>-0.0149</PDBx:U23>
         <PDBx:U33>0.1680</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="798">
         <PDBx:U11>0.2449</PDBx:U11>
         <PDBx:U12>-0.0262</PDBx:U12>
         <PDBx:U13>-0.0150</PDBx:U13>
         <PDBx:U22>0.2009</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.1853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="799">
         <PDBx:U11>0.2186</PDBx:U11>
         <PDBx:U12>0.0010</PDBx:U12>
         <PDBx:U13>-0.0237</PDBx:U13>
         <PDBx:U22>0.2050</PDBx:U22>
         <PDBx:U23>0.0131</PDBx:U23>
         <PDBx:U33>0.1695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="800">
         <PDBx:U11>0.1845</PDBx:U11>
         <PDBx:U12>-0.0211</PDBx:U12>
         <PDBx:U13>-0.0050</PDBx:U13>
         <PDBx:U22>0.2146</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.1544</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="801">
         <PDBx:U11>0.2694</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.2193</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.1610</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="802">
         <PDBx:U11>0.2655</PDBx:U11>
         <PDBx:U12>-0.0509</PDBx:U12>
         <PDBx:U13>0.0528</PDBx:U13>
         <PDBx:U22>0.3116</PDBx:U22>
         <PDBx:U23>-0.0463</PDBx:U23>
         <PDBx:U33>0.2682</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="803">
         <PDBx:U11>0.4197</PDBx:U11>
         <PDBx:U12>-0.1567</PDBx:U12>
         <PDBx:U13>0.0344</PDBx:U13>
         <PDBx:U22>0.4140</PDBx:U22>
         <PDBx:U23>-0.1430</PDBx:U23>
         <PDBx:U33>0.4460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="804">
         <PDBx:U11>0.2786</PDBx:U11>
         <PDBx:U12>0.0152</PDBx:U12>
         <PDBx:U13>-0.0408</PDBx:U13>
         <PDBx:U22>0.4619</PDBx:U22>
         <PDBx:U23>0.1086</PDBx:U23>
         <PDBx:U33>0.2962</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="805">
         <PDBx:U11>0.2110</PDBx:U11>
         <PDBx:U12>-0.0075</PDBx:U12>
         <PDBx:U13>0.0129</PDBx:U13>
         <PDBx:U22>0.1991</PDBx:U22>
         <PDBx:U23>-0.0223</PDBx:U23>
         <PDBx:U33>0.1870</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="806">
         <PDBx:U11>0.2568</PDBx:U11>
         <PDBx:U12>-0.0290</PDBx:U12>
         <PDBx:U13>0.0182</PDBx:U13>
         <PDBx:U22>0.1833</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.1652</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="807">
         <PDBx:U11>0.1953</PDBx:U11>
         <PDBx:U12>0.0099</PDBx:U12>
         <PDBx:U13>-0.0211</PDBx:U13>
         <PDBx:U22>0.2249</PDBx:U22>
         <PDBx:U23>0.0241</PDBx:U23>
         <PDBx:U33>0.2057</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="808">
         <PDBx:U11>0.2190</PDBx:U11>
         <PDBx:U12>0.0179</PDBx:U12>
         <PDBx:U13>-0.0220</PDBx:U13>
         <PDBx:U22>0.2314</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.2110</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="809">
         <PDBx:U11>0.2488</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>0.0233</PDBx:U13>
         <PDBx:U22>0.1946</PDBx:U22>
         <PDBx:U23>-0.0166</PDBx:U23>
         <PDBx:U33>0.2535</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="810">
         <PDBx:U11>0.2569</PDBx:U11>
         <PDBx:U12>0.0011</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.2090</PDBx:U22>
         <PDBx:U23>-0.0142</PDBx:U23>
         <PDBx:U33>0.2324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="811">
         <PDBx:U11>0.2516</PDBx:U11>
         <PDBx:U12>-0.0300</PDBx:U12>
         <PDBx:U13>0.0403</PDBx:U13>
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         <PDBx:U23>-0.0159</PDBx:U23>
         <PDBx:U33>0.2568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="812">
         <PDBx:U11>0.2201</PDBx:U11>
         <PDBx:U12>-0.0097</PDBx:U12>
         <PDBx:U13>-0.0240</PDBx:U13>
         <PDBx:U22>0.2109</PDBx:U22>
         <PDBx:U23>0.0156</PDBx:U23>
         <PDBx:U33>0.2419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="813">
         <PDBx:U11>0.2414</PDBx:U11>
         <PDBx:U12>-0.0281</PDBx:U12>
         <PDBx:U13>-0.0503</PDBx:U13>
         <PDBx:U22>0.1961</PDBx:U22>
         <PDBx:U23>0.0254</PDBx:U23>
         <PDBx:U33>0.2404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="814">
         <PDBx:U11>0.2361</PDBx:U11>
         <PDBx:U12>0.0194</PDBx:U12>
         <PDBx:U13>-0.0137</PDBx:U13>
         <PDBx:U22>0.2221</PDBx:U22>
         <PDBx:U23>0.0089</PDBx:U23>
         <PDBx:U33>0.1936</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>0.0070</PDBx:U12>
         <PDBx:U13>0.0028</PDBx:U13>
         <PDBx:U22>0.2066</PDBx:U22>
         <PDBx:U23>0.0146</PDBx:U23>
         <PDBx:U33>0.2238</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="816">
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         <PDBx:U13>-0.0724</PDBx:U13>
         <PDBx:U22>0.3082</PDBx:U22>
         <PDBx:U23>0.0449</PDBx:U23>
         <PDBx:U33>0.2889</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0350</PDBx:U13>
         <PDBx:U22>0.3956</PDBx:U22>
         <PDBx:U23>0.0551</PDBx:U23>
         <PDBx:U33>0.3681</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="818">
         <PDBx:U11>0.8358</PDBx:U11>
         <PDBx:U12>0.0366</PDBx:U12>
         <PDBx:U13>0.1686</PDBx:U13>
         <PDBx:U22>0.5320</PDBx:U22>
         <PDBx:U23>0.1552</PDBx:U23>
         <PDBx:U33>0.8929</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="819">
         <PDBx:U11>0.4612</PDBx:U11>
         <PDBx:U12>0.1610</PDBx:U12>
         <PDBx:U13>-0.0388</PDBx:U13>
         <PDBx:U22>1.3578</PDBx:U22>
         <PDBx:U23>-0.1572</PDBx:U23>
         <PDBx:U33>1.0734</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="820">
         <PDBx:U11>0.4367</PDBx:U11>
         <PDBx:U12>-0.0239</PDBx:U12>
         <PDBx:U13>0.0520</PDBx:U13>
         <PDBx:U22>1.3777</PDBx:U22>
         <PDBx:U23>-0.0262</PDBx:U23>
         <PDBx:U33>0.7359</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="821">
         <PDBx:U11>0.2091</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>-0.0253</PDBx:U13>
         <PDBx:U22>0.1807</PDBx:U22>
         <PDBx:U23>0.0059</PDBx:U23>
         <PDBx:U33>0.1707</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="822">
         <PDBx:U11>0.2188</PDBx:U11>
         <PDBx:U12>0.0139</PDBx:U12>
         <PDBx:U13>-0.0165</PDBx:U13>
         <PDBx:U22>0.1642</PDBx:U22>
         <PDBx:U23>-0.0076</PDBx:U23>
         <PDBx:U33>0.1934</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.1961</PDBx:U11>
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         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1733</PDBx:U22>
         <PDBx:U23>0.0086</PDBx:U23>
         <PDBx:U33>0.1805</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0096</PDBx:U23>
         <PDBx:U33>0.1725</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="826">
         <PDBx:U11>0.2676</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="827">
         <PDBx:U11>0.3149</PDBx:U11>
         <PDBx:U12>0.0142</PDBx:U12>
         <PDBx:U13>0.0450</PDBx:U13>
         <PDBx:U22>0.2670</PDBx:U22>
         <PDBx:U23>0.0059</PDBx:U23>
         <PDBx:U33>0.2532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="828">
         <PDBx:U11>0.3094</PDBx:U11>
         <PDBx:U12>-0.0221</PDBx:U12>
         <PDBx:U13>0.0316</PDBx:U13>
         <PDBx:U22>0.2073</PDBx:U22>
         <PDBx:U23>-0.0239</PDBx:U23>
         <PDBx:U33>0.2912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="829">
         <PDBx:U11>0.4082</PDBx:U11>
         <PDBx:U12>-0.0321</PDBx:U12>
         <PDBx:U13>0.0494</PDBx:U13>
         <PDBx:U22>0.2765</PDBx:U22>
         <PDBx:U23>-0.0212</PDBx:U23>
         <PDBx:U33>0.3733</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="830">
         <PDBx:U11>0.1919</PDBx:U11>
         <PDBx:U12>0.0029</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.1789</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.1645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="831">
         <PDBx:U11>0.1689</PDBx:U11>
         <PDBx:U12>-0.0404</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.1624</PDBx:U22>
         <PDBx:U23>-0.0103</PDBx:U23>
         <PDBx:U33>0.1858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="832">
         <PDBx:U11>0.1915</PDBx:U11>
         <PDBx:U12>-0.0173</PDBx:U12>
         <PDBx:U13>-0.0142</PDBx:U13>
         <PDBx:U22>0.2034</PDBx:U22>
         <PDBx:U23>0.0054</PDBx:U23>
         <PDBx:U33>0.1908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="833">
         <PDBx:U11>0.2164</PDBx:U11>
         <PDBx:U12>-0.0184</PDBx:U12>
         <PDBx:U13>-0.0163</PDBx:U13>
         <PDBx:U22>0.1779</PDBx:U22>
         <PDBx:U23>0.0093</PDBx:U23>
         <PDBx:U33>0.1698</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="834">
         <PDBx:U11>0.1649</PDBx:U11>
         <PDBx:U12>-0.0229</PDBx:U12>
         <PDBx:U13>0.0333</PDBx:U13>
         <PDBx:U22>0.1505</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.1994</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="835">
         <PDBx:U11>0.1537</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.1721</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1803</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="836">
         <PDBx:U11>0.2226</PDBx:U11>
         <PDBx:U12>-0.0211</PDBx:U12>
         <PDBx:U13>-0.0154</PDBx:U13>
         <PDBx:U22>0.1768</PDBx:U22>
         <PDBx:U23>0.0103</PDBx:U23>
         <PDBx:U33>0.2152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="837">
         <PDBx:U11>0.2152</PDBx:U11>
         <PDBx:U12>0.0374</PDBx:U12>
         <PDBx:U13>-0.0015</PDBx:U13>
         <PDBx:U22>0.1804</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.1821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="838">
         <PDBx:U11>0.2117</PDBx:U11>
         <PDBx:U12>0.0283</PDBx:U12>
         <PDBx:U13>-0.0126</PDBx:U13>
         <PDBx:U22>0.1959</PDBx:U22>
         <PDBx:U23>-0.0120</PDBx:U23>
         <PDBx:U33>0.2008</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="839">
         <PDBx:U11>0.1936</PDBx:U11>
         <PDBx:U12>0.0134</PDBx:U12>
         <PDBx:U13>0.0077</PDBx:U13>
         <PDBx:U22>0.2019</PDBx:U22>
         <PDBx:U23>0.0626</PDBx:U23>
         <PDBx:U33>0.1926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="840">
         <PDBx:U11>0.1831</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>-0.0072</PDBx:U13>
         <PDBx:U22>0.2108</PDBx:U22>
         <PDBx:U23>0.0047</PDBx:U23>
         <PDBx:U33>0.2019</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="841">
         <PDBx:U11>0.2163</PDBx:U11>
         <PDBx:U12>0.0297</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1920</PDBx:U22>
         <PDBx:U23>0.0262</PDBx:U23>
         <PDBx:U33>0.1913</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="842">
         <PDBx:U11>0.1883</PDBx:U11>
         <PDBx:U12>0.0170</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.1810</PDBx:U22>
         <PDBx:U23>0.0337</PDBx:U23>
         <PDBx:U33>0.1831</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.0061</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0140</PDBx:U23>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0087</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0027</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0398</PDBx:U13>
         <PDBx:U22>0.2187</PDBx:U22>
         <PDBx:U23>0.0638</PDBx:U23>
         <PDBx:U33>0.3600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="852">
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         <PDBx:U13>0.0284</PDBx:U13>
         <PDBx:U22>0.3877</PDBx:U22>
         <PDBx:U23>0.0765</PDBx:U23>
         <PDBx:U33>0.4341</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="853">
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         <PDBx:U22>0.3904</PDBx:U22>
         <PDBx:U23>0.0308</PDBx:U23>
         <PDBx:U33>0.4933</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U13>0.0505</PDBx:U13>
         <PDBx:U22>0.3428</PDBx:U22>
         <PDBx:U23>0.0932</PDBx:U23>
         <PDBx:U33>0.5137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U22>0.1882</PDBx:U22>
         <PDBx:U23>-0.0091</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>-0.0049</PDBx:U13>
         <PDBx:U22>0.1893</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.1927</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0048</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0117</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0085</PDBx:U23>
         <PDBx:U33>0.1981</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="860">
         <PDBx:U11>0.2687</PDBx:U11>
         <PDBx:U12>0.0030</PDBx:U12>
         <PDBx:U13>0.0522</PDBx:U13>
         <PDBx:U22>0.2303</PDBx:U22>
         <PDBx:U23>-0.0135</PDBx:U23>
         <PDBx:U33>0.2277</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="861">
         <PDBx:U11>0.2714</PDBx:U11>
         <PDBx:U12>0.0201</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.2959</PDBx:U22>
         <PDBx:U23>0.0151</PDBx:U23>
         <PDBx:U33>0.2471</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="862">
         <PDBx:U11>0.4126</PDBx:U11>
         <PDBx:U12>-0.0686</PDBx:U12>
         <PDBx:U13>0.0396</PDBx:U13>
         <PDBx:U22>0.3417</PDBx:U22>
         <PDBx:U23>-0.0757</PDBx:U23>
         <PDBx:U33>0.2731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="863">
         <PDBx:U11>0.2146</PDBx:U11>
         <PDBx:U12>0.0173</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.1792</PDBx:U22>
         <PDBx:U23>-0.0086</PDBx:U23>
         <PDBx:U33>0.1865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="864">
         <PDBx:U11>0.2149</PDBx:U11>
         <PDBx:U12>0.0251</PDBx:U12>
         <PDBx:U13>-0.0130</PDBx:U13>
         <PDBx:U22>0.1726</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.1819</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="865">
         <PDBx:U11>0.1973</PDBx:U11>
         <PDBx:U12>0.0093</PDBx:U12>
         <PDBx:U13>-0.0165</PDBx:U13>
         <PDBx:U22>0.1798</PDBx:U22>
         <PDBx:U23>-0.0100</PDBx:U23>
         <PDBx:U33>0.1822</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="866">
         <PDBx:U11>0.1971</PDBx:U11>
         <PDBx:U12>0.0077</PDBx:U12>
         <PDBx:U13>0.0201</PDBx:U13>
         <PDBx:U22>0.2017</PDBx:U22>
         <PDBx:U23>0.0170</PDBx:U23>
         <PDBx:U33>0.1999</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="867">
         <PDBx:U11>0.2102</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>-0.0156</PDBx:U13>
         <PDBx:U22>0.1669</PDBx:U22>
         <PDBx:U23>0.0161</PDBx:U23>
         <PDBx:U33>0.2171</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="868">
         <PDBx:U11>0.2261</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.1915</PDBx:U22>
         <PDBx:U23>0.0045</PDBx:U23>
         <PDBx:U33>0.2101</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="869">
         <PDBx:U11>0.1655</PDBx:U11>
         <PDBx:U12>-0.0167</PDBx:U12>
         <PDBx:U13>-0.0050</PDBx:U13>
         <PDBx:U22>0.1870</PDBx:U22>
         <PDBx:U23>0.0120</PDBx:U23>
         <PDBx:U33>0.1878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="870">
         <PDBx:U11>0.1772</PDBx:U11>
         <PDBx:U12>-0.0229</PDBx:U12>
         <PDBx:U13>-0.0058</PDBx:U13>
         <PDBx:U22>0.1869</PDBx:U22>
         <PDBx:U23>0.0384</PDBx:U23>
         <PDBx:U33>0.2059</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="871">
         <PDBx:U11>0.2049</PDBx:U11>
         <PDBx:U12>-0.0036</PDBx:U12>
         <PDBx:U13>0.0192</PDBx:U13>
         <PDBx:U22>0.1901</PDBx:U22>
         <PDBx:U23>0.0213</PDBx:U23>
         <PDBx:U33>0.2119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="872">
         <PDBx:U11>0.1823</PDBx:U11>
         <PDBx:U12>-0.0027</PDBx:U12>
         <PDBx:U13>0.0059</PDBx:U13>
         <PDBx:U22>0.1990</PDBx:U22>
         <PDBx:U23>0.0108</PDBx:U23>
         <PDBx:U33>0.1832</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="873">
         <PDBx:U11>0.2049</PDBx:U11>
         <PDBx:U12>-0.0206</PDBx:U12>
         <PDBx:U13>-0.0287</PDBx:U13>
         <PDBx:U22>0.2131</PDBx:U22>
         <PDBx:U23>0.0099</PDBx:U23>
         <PDBx:U33>0.2461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="874">
         <PDBx:U11>0.2269</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>-0.0127</PDBx:U13>
         <PDBx:U22>0.3539</PDBx:U22>
         <PDBx:U23>0.0910</PDBx:U23>
         <PDBx:U33>0.2488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="875">
         <PDBx:U11>0.2179</PDBx:U11>
         <PDBx:U12>0.0648</PDBx:U12>
         <PDBx:U13>-0.0571</PDBx:U13>
         <PDBx:U22>0.3567</PDBx:U22>
         <PDBx:U23>0.0544</PDBx:U23>
         <PDBx:U33>0.3855</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="876">
         <PDBx:U11>0.2766</PDBx:U11>
         <PDBx:U12>-0.0108</PDBx:U12>
         <PDBx:U13>-0.0180</PDBx:U13>
         <PDBx:U22>0.3895</PDBx:U22>
         <PDBx:U23>0.0044</PDBx:U23>
         <PDBx:U33>0.3301</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="877">
         <PDBx:U11>0.3720</PDBx:U11>
         <PDBx:U12>-0.0345</PDBx:U12>
         <PDBx:U13>-0.0267</PDBx:U13>
         <PDBx:U22>0.4466</PDBx:U22>
         <PDBx:U23>0.0145</PDBx:U23>
         <PDBx:U33>0.3102</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="878">
         <PDBx:U11>0.1936</PDBx:U11>
         <PDBx:U12>0.0044</PDBx:U12>
         <PDBx:U13>-0.0126</PDBx:U13>
         <PDBx:U22>0.1866</PDBx:U22>
         <PDBx:U23>0.0135</PDBx:U23>
         <PDBx:U33>0.2034</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="879">
         <PDBx:U11>0.1931</PDBx:U11>
         <PDBx:U12>0.0039</PDBx:U12>
         <PDBx:U13>-0.0172</PDBx:U13>
         <PDBx:U22>0.1589</PDBx:U22>
         <PDBx:U23>0.0066</PDBx:U23>
         <PDBx:U33>0.1924</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="880">
         <PDBx:U11>0.1880</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.2103</PDBx:U22>
         <PDBx:U23>-0.0071</PDBx:U23>
         <PDBx:U33>0.2053</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="881">
         <PDBx:U11>0.2376</PDBx:U11>
         <PDBx:U12>-0.0161</PDBx:U12>
         <PDBx:U13>-0.0110</PDBx:U13>
         <PDBx:U22>0.2074</PDBx:U22>
         <PDBx:U23>-0.0110</PDBx:U23>
         <PDBx:U33>0.1952</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="882">
         <PDBx:U11>0.2440</PDBx:U11>
         <PDBx:U12>0.0353</PDBx:U12>
         <PDBx:U13>-0.0059</PDBx:U13>
         <PDBx:U22>0.1962</PDBx:U22>
         <PDBx:U23>0.0134</PDBx:U23>
         <PDBx:U33>0.1870</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="883">
         <PDBx:U11>0.2582</PDBx:U11>
         <PDBx:U12>0.0155</PDBx:U12>
         <PDBx:U13>-0.0040</PDBx:U13>
         <PDBx:U22>0.2294</PDBx:U22>
         <PDBx:U23>0.0468</PDBx:U23>
         <PDBx:U33>0.2097</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="884">
         <PDBx:U11>0.3097</PDBx:U11>
         <PDBx:U12>0.0294</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.2329</PDBx:U22>
         <PDBx:U23>0.0114</PDBx:U23>
         <PDBx:U33>0.2695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="885">
         <PDBx:U11>0.2801</PDBx:U11>
         <PDBx:U12>-0.0172</PDBx:U12>
         <PDBx:U13>-0.0327</PDBx:U13>
         <PDBx:U22>0.2188</PDBx:U22>
         <PDBx:U23>0.0046</PDBx:U23>
         <PDBx:U33>0.2530</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="886">
         <PDBx:U11>0.1862</PDBx:U11>
         <PDBx:U12>0.0028</PDBx:U12>
         <PDBx:U13>-0.0188</PDBx:U13>
         <PDBx:U22>0.1627</PDBx:U22>
         <PDBx:U23>-0.0113</PDBx:U23>
         <PDBx:U33>0.1726</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>505</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="887">
         <PDBx:U11>0.1710</PDBx:U11>
         <PDBx:U12>-0.0098</PDBx:U12>
         <PDBx:U13>-0.0141</PDBx:U13>
         <PDBx:U22>0.1580</PDBx:U22>
         <PDBx:U23>-0.0254</PDBx:U23>
         <PDBx:U33>0.1909</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>505</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="888">
         <PDBx:U11>0.1665</PDBx:U11>
         <PDBx:U12>0.0137</PDBx:U12>
         <PDBx:U13>-0.0087</PDBx:U13>
         <PDBx:U22>0.1637</PDBx:U22>
         <PDBx:U23>0.0151</PDBx:U23>
         <PDBx:U33>0.1615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>505</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="889">
         <PDBx:U11>0.1851</PDBx:U11>
         <PDBx:U12>0.0116</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.1711</PDBx:U22>
         <PDBx:U23>0.0075</PDBx:U23>
         <PDBx:U33>0.1814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>505</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="890">
         <PDBx:U11>0.1645</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0091</PDBx:U13>
         <PDBx:U22>0.1586</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>505</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="891">
         <PDBx:U11>0.2085</PDBx:U11>
         <PDBx:U12>0.0062</PDBx:U12>
         <PDBx:U13>-0.0146</PDBx:U13>
         <PDBx:U22>0.2045</PDBx:U22>
         <PDBx:U23>-0.0286</PDBx:U23>
         <PDBx:U33>0.1915</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>505</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="892">
         <PDBx:U11>0.2120</PDBx:U11>
         <PDBx:U12>0.0163</PDBx:U12>
         <PDBx:U13>0.0199</PDBx:U13>
         <PDBx:U22>0.1735</PDBx:U22>
         <PDBx:U23>-0.0111</PDBx:U23>
         <PDBx:U33>0.1941</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>505</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="893">
         <PDBx:U11>0.1604</PDBx:U11>
         <PDBx:U12>0.0050</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.1671</PDBx:U22>
         <PDBx:U23>0.0103</PDBx:U23>
         <PDBx:U33>0.1802</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="894">
         <PDBx:U11>0.1775</PDBx:U11>
         <PDBx:U12>-0.0109</PDBx:U12>
         <PDBx:U13>0.0046</PDBx:U13>
         <PDBx:U22>0.1608</PDBx:U22>
         <PDBx:U23>0.0319</PDBx:U23>
         <PDBx:U33>0.2147</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="895">
         <PDBx:U11>0.1895</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0069</PDBx:U13>
         <PDBx:U22>0.1792</PDBx:U22>
         <PDBx:U23>0.0124</PDBx:U23>
         <PDBx:U33>0.1878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="896">
         <PDBx:U11>0.2145</PDBx:U11>
         <PDBx:U12>0.0070</PDBx:U12>
         <PDBx:U13>0.0211</PDBx:U13>
         <PDBx:U22>0.1979</PDBx:U22>
         <PDBx:U23>0.0186</PDBx:U23>
         <PDBx:U33>0.2027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="897">
         <PDBx:U11>0.1919</PDBx:U11>
         <PDBx:U12>0.0209</PDBx:U12>
         <PDBx:U13>0.0124</PDBx:U13>
         <PDBx:U22>0.1576</PDBx:U22>
         <PDBx:U23>0.0184</PDBx:U23>
         <PDBx:U33>0.2068</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="898">
         <PDBx:U11>0.2175</PDBx:U11>
         <PDBx:U12>0.0124</PDBx:U12>
         <PDBx:U13>0.0105</PDBx:U13>
         <PDBx:U22>0.1975</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.2152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="899">
         <PDBx:U11>0.1901</PDBx:U11>
         <PDBx:U12>0.0076</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.1734</PDBx:U22>
         <PDBx:U23>-0.0011</PDBx:U23>
         <PDBx:U33>0.1917</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="900">
         <PDBx:U11>0.2094</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.1861</PDBx:U22>
         <PDBx:U23>0.0142</PDBx:U23>
         <PDBx:U33>0.1660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="901">
         <PDBx:U11>0.1986</PDBx:U11>
         <PDBx:U12>0.0042</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.2092</PDBx:U22>
         <PDBx:U23>0.0206</PDBx:U23>
         <PDBx:U33>0.1750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="902">
         <PDBx:U11>0.1998</PDBx:U11>
         <PDBx:U12>-0.0075</PDBx:U12>
         <PDBx:U13>0.0097</PDBx:U13>
         <PDBx:U22>0.2218</PDBx:U22>
         <PDBx:U23>0.0187</PDBx:U23>
         <PDBx:U33>0.2091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="903">
         <PDBx:U11>0.2213</PDBx:U11>
         <PDBx:U12>0.0055</PDBx:U12>
         <PDBx:U13>-0.0440</PDBx:U13>
         <PDBx:U22>0.1894</PDBx:U22>
         <PDBx:U23>0.0240</PDBx:U23>
         <PDBx:U33>0.1788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="904">
         <PDBx:U11>0.1987</PDBx:U11>
         <PDBx:U12>0.0139</PDBx:U12>
         <PDBx:U13>-0.0491</PDBx:U13>
         <PDBx:U22>0.1905</PDBx:U22>
         <PDBx:U23>0.0334</PDBx:U23>
         <PDBx:U33>0.2065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="905">
         <PDBx:U11>0.3143</PDBx:U11>
         <PDBx:U12>-0.0084</PDBx:U12>
         <PDBx:U13>-0.0195</PDBx:U13>
         <PDBx:U22>0.2730</PDBx:U22>
         <PDBx:U23>0.0071</PDBx:U23>
         <PDBx:U33>0.2534</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="906">
         <PDBx:U11>0.3575</PDBx:U11>
         <PDBx:U12>0.0587</PDBx:U12>
         <PDBx:U13>-0.0660</PDBx:U13>
         <PDBx:U22>0.3802</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.3138</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="907">
         <PDBx:U11>0.3615</PDBx:U11>
         <PDBx:U12>0.0624</PDBx:U12>
         <PDBx:U13>-0.0825</PDBx:U13>
         <PDBx:U22>0.3205</PDBx:U22>
         <PDBx:U23>-0.0419</PDBx:U23>
         <PDBx:U33>0.3513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="908">
         <PDBx:U11>0.2007</PDBx:U11>
         <PDBx:U12>-0.0184</PDBx:U12>
         <PDBx:U13>-0.0299</PDBx:U13>
         <PDBx:U22>0.1705</PDBx:U22>
         <PDBx:U23>0.0228</PDBx:U23>
         <PDBx:U33>0.2051</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U12>0.0058</PDBx:U12>
         <PDBx:U13>-0.0168</PDBx:U13>
         <PDBx:U22>0.2022</PDBx:U22>
         <PDBx:U23>0.0090</PDBx:U23>
         <PDBx:U33>0.1693</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="910">
         <PDBx:U11>0.1757</PDBx:U11>
         <PDBx:U12>-0.0148</PDBx:U12>
         <PDBx:U13>-0.0123</PDBx:U13>
         <PDBx:U22>0.1850</PDBx:U22>
         <PDBx:U23>0.0030</PDBx:U23>
         <PDBx:U33>0.1872</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="911">
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         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.2018</PDBx:U22>
         <PDBx:U23>0.0046</PDBx:U23>
         <PDBx:U33>0.2093</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="912">
         <PDBx:U11>0.2584</PDBx:U11>
         <PDBx:U12>0.0235</PDBx:U12>
         <PDBx:U13>0.0434</PDBx:U13>
         <PDBx:U22>0.2006</PDBx:U22>
         <PDBx:U23>0.0027</PDBx:U23>
         <PDBx:U33>0.1946</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="913">
         <PDBx:U11>0.2183</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>-0.0105</PDBx:U13>
         <PDBx:U22>0.1607</PDBx:U22>
         <PDBx:U23>-0.0087</PDBx:U23>
         <PDBx:U33>0.1884</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="914">
         <PDBx:U11>0.1943</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.2257</PDBx:U22>
         <PDBx:U23>-0.0305</PDBx:U23>
         <PDBx:U33>0.1988</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="915">
         <PDBx:U11>0.2075</PDBx:U11>
         <PDBx:U12>-0.0172</PDBx:U12>
         <PDBx:U13>0.0059</PDBx:U13>
         <PDBx:U22>0.2183</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.2022</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="916">
         <PDBx:U11>0.2125</PDBx:U11>
         <PDBx:U12>-0.0348</PDBx:U12>
         <PDBx:U13>0.0079</PDBx:U13>
         <PDBx:U22>0.2157</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1801</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="917">
         <PDBx:U11>0.1805</PDBx:U11>
         <PDBx:U12>0.0073</PDBx:U12>
         <PDBx:U13>0.0097</PDBx:U13>
         <PDBx:U22>0.1831</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.2172</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="918">
         <PDBx:U11>0.1636</PDBx:U11>
         <PDBx:U12>0.0071</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1975</PDBx:U22>
         <PDBx:U23>0.0159</PDBx:U23>
         <PDBx:U33>0.2053</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="919">
         <PDBx:U11>0.2073</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.1917</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.2049</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="920">
         <PDBx:U11>0.2968</PDBx:U11>
         <PDBx:U12>0.0205</PDBx:U12>
         <PDBx:U13>-0.0207</PDBx:U13>
         <PDBx:U22>0.2191</PDBx:U22>
         <PDBx:U23>-0.0208</PDBx:U23>
         <PDBx:U33>0.2062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.1896</PDBx:U11>
         <PDBx:U12>0.0116</PDBx:U12>
         <PDBx:U13>0.0105</PDBx:U13>
         <PDBx:U22>0.1772</PDBx:U22>
         <PDBx:U23>0.0078</PDBx:U23>
         <PDBx:U33>0.2214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U12>0.0171</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.2251</PDBx:U22>
         <PDBx:U23>0.0158</PDBx:U23>
         <PDBx:U33>0.2098</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="923">
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         <PDBx:U12>-0.0112</PDBx:U12>
         <PDBx:U13>0.0195</PDBx:U13>
         <PDBx:U22>0.2114</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.2182</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="924">
         <PDBx:U11>0.2312</PDBx:U11>
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         <PDBx:U13>0.0227</PDBx:U13>
         <PDBx:U22>0.2215</PDBx:U22>
         <PDBx:U23>0.0395</PDBx:U23>
         <PDBx:U33>0.2362</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="925">
         <PDBx:U11>0.1750</PDBx:U11>
         <PDBx:U12>0.0430</PDBx:U12>
         <PDBx:U13>0.0108</PDBx:U13>
         <PDBx:U22>0.2245</PDBx:U22>
         <PDBx:U23>0.0256</PDBx:U23>
         <PDBx:U33>0.1804</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="926">
         <PDBx:U11>0.2410</PDBx:U11>
         <PDBx:U12>0.0690</PDBx:U12>
         <PDBx:U13>0.0478</PDBx:U13>
         <PDBx:U22>0.2682</PDBx:U22>
         <PDBx:U23>-0.0460</PDBx:U23>
         <PDBx:U33>0.2944</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="927">
         <PDBx:U11>0.4182</PDBx:U11>
         <PDBx:U12>-0.0319</PDBx:U12>
         <PDBx:U13>0.0230</PDBx:U13>
         <PDBx:U22>0.4468</PDBx:U22>
         <PDBx:U23>-0.0204</PDBx:U23>
         <PDBx:U33>0.5317</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="928">
         <PDBx:U11>0.4566</PDBx:U11>
         <PDBx:U12>0.0615</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.5892</PDBx:U22>
         <PDBx:U23>-0.1550</PDBx:U23>
         <PDBx:U33>0.6826</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="929">
         <PDBx:U11>0.6449</PDBx:U11>
         <PDBx:U12>-0.0714</PDBx:U12>
         <PDBx:U13>0.1026</PDBx:U13>
         <PDBx:U22>0.4805</PDBx:U22>
         <PDBx:U23>-0.0429</PDBx:U23>
         <PDBx:U33>0.6387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="930">
         <PDBx:U11>0.2034</PDBx:U11>
         <PDBx:U12>-0.0106</PDBx:U12>
         <PDBx:U13>0.0178</PDBx:U13>
         <PDBx:U22>0.1798</PDBx:U22>
         <PDBx:U23>0.0330</PDBx:U23>
         <PDBx:U33>0.2287</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="931">
         <PDBx:U11>0.2134</PDBx:U11>
         <PDBx:U12>-0.0269</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.1932</PDBx:U22>
         <PDBx:U23>0.0177</PDBx:U23>
         <PDBx:U33>0.1909</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="932">
         <PDBx:U11>0.2086</PDBx:U11>
         <PDBx:U12>0.0004</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.2386</PDBx:U22>
         <PDBx:U23>0.0317</PDBx:U23>
         <PDBx:U33>0.2178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="933">
         <PDBx:U11>0.2024</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>0.0231</PDBx:U13>
         <PDBx:U22>0.2374</PDBx:U22>
         <PDBx:U23>0.0284</PDBx:U23>
         <PDBx:U33>0.2311</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="934">
         <PDBx:U11>0.2359</PDBx:U11>
         <PDBx:U12>-0.0121</PDBx:U12>
         <PDBx:U13>-0.0335</PDBx:U13>
         <PDBx:U22>0.1747</PDBx:U22>
         <PDBx:U23>0.0122</PDBx:U23>
         <PDBx:U33>0.2346</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="935">
         <PDBx:U11>0.2336</PDBx:U11>
         <PDBx:U12>-0.0032</PDBx:U12>
         <PDBx:U13>-0.0077</PDBx:U13>
         <PDBx:U22>0.2325</PDBx:U22>
         <PDBx:U23>0.0331</PDBx:U23>
         <PDBx:U33>0.2364</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="936">
         <PDBx:U11>0.2785</PDBx:U11>
         <PDBx:U12>-0.0353</PDBx:U12>
         <PDBx:U13>0.0298</PDBx:U13>
         <PDBx:U22>0.2272</PDBx:U22>
         <PDBx:U23>0.0179</PDBx:U23>
         <PDBx:U33>0.2649</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="937">
         <PDBx:U11>0.2209</PDBx:U11>
         <PDBx:U12>-0.0164</PDBx:U12>
         <PDBx:U13>-0.0393</PDBx:U13>
         <PDBx:U22>0.2280</PDBx:U22>
         <PDBx:U23>0.0215</PDBx:U23>
         <PDBx:U33>0.2242</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="938">
         <PDBx:U11>0.2597</PDBx:U11>
         <PDBx:U12>-0.0008</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.2254</PDBx:U22>
         <PDBx:U23>0.0327</PDBx:U23>
         <PDBx:U33>0.2395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="939">
         <PDBx:U11>0.2536</PDBx:U11>
         <PDBx:U12>0.0003</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.2331</PDBx:U22>
         <PDBx:U23>0.0382</PDBx:U23>
         <PDBx:U33>0.2552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="940">
         <PDBx:U11>0.2523</PDBx:U11>
         <PDBx:U12>-0.0099</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.2335</PDBx:U22>
         <PDBx:U23>0.0384</PDBx:U23>
         <PDBx:U33>0.2794</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="941">
         <PDBx:U11>0.2612</PDBx:U11>
         <PDBx:U12>-0.0255</PDBx:U12>
         <PDBx:U13>0.0289</PDBx:U13>
         <PDBx:U22>0.2317</PDBx:U22>
         <PDBx:U23>0.0341</PDBx:U23>
         <PDBx:U33>0.2883</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="942">
         <PDBx:U11>0.1875</PDBx:U11>
         <PDBx:U12>-0.0182</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.2037</PDBx:U22>
         <PDBx:U23>0.0144</PDBx:U23>
         <PDBx:U33>0.2175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="943">
         <PDBx:U11>0.2088</PDBx:U11>
         <PDBx:U12>-0.0031</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.2172</PDBx:U22>
         <PDBx:U23>0.0101</PDBx:U23>
         <PDBx:U33>0.2141</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="944">
         <PDBx:U11>0.2578</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
         <PDBx:U22>0.2297</PDBx:U22>
         <PDBx:U23>0.0071</PDBx:U23>
         <PDBx:U33>0.2242</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="945">
         <PDBx:U11>0.2410</PDBx:U11>
         <PDBx:U12>0.0042</PDBx:U12>
         <PDBx:U13>0.0161</PDBx:U13>
         <PDBx:U22>0.2401</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.2179</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="946">
         <PDBx:U11>0.2220</PDBx:U11>
         <PDBx:U12>0.0279</PDBx:U12>
         <PDBx:U13>0.0270</PDBx:U13>
         <PDBx:U22>0.2104</PDBx:U22>
         <PDBx:U23>0.0146</PDBx:U23>
         <PDBx:U33>0.2229</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="947">
         <PDBx:U11>0.2334</PDBx:U11>
         <PDBx:U12>0.0096</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.1942</PDBx:U22>
         <PDBx:U23>0.0093</PDBx:U23>
         <PDBx:U33>0.2009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="948">
         <PDBx:U11>0.2304</PDBx:U11>
         <PDBx:U12>0.0114</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.2304</PDBx:U22>
         <PDBx:U23>0.0274</PDBx:U23>
         <PDBx:U33>0.2437</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="949">
         <PDBx:U11>0.2324</PDBx:U11>
         <PDBx:U12>-0.0344</PDBx:U12>
         <PDBx:U13>0.0213</PDBx:U13>
         <PDBx:U22>0.2097</PDBx:U22>
         <PDBx:U23>0.0088</PDBx:U23>
         <PDBx:U33>0.2152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="950">
         <PDBx:U11>0.2427</PDBx:U11>
         <PDBx:U12>0.0061</PDBx:U12>
         <PDBx:U13>0.0244</PDBx:U13>
         <PDBx:U22>0.2233</PDBx:U22>
         <PDBx:U23>0.0072</PDBx:U23>
         <PDBx:U33>0.2070</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="951">
         <PDBx:U11>0.2896</PDBx:U11>
         <PDBx:U12>0.0326</PDBx:U12>
         <PDBx:U13>0.0526</PDBx:U13>
         <PDBx:U22>0.2047</PDBx:U22>
         <PDBx:U23>0.0193</PDBx:U23>
         <PDBx:U33>0.2756</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="952">
         <PDBx:U11>0.2568</PDBx:U11>
         <PDBx:U12>0.0066</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.2698</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.2454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="953">
         <PDBx:U11>0.3002</PDBx:U11>
         <PDBx:U12>0.0267</PDBx:U12>
         <PDBx:U13>0.0503</PDBx:U13>
         <PDBx:U22>0.2318</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.2625</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="954">
         <PDBx:U11>0.3071</PDBx:U11>
         <PDBx:U12>0.0429</PDBx:U12>
         <PDBx:U13>0.0652</PDBx:U13>
         <PDBx:U22>0.2158</PDBx:U22>
         <PDBx:U23>0.0213</PDBx:U23>
         <PDBx:U33>0.2487</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="955">
         <PDBx:U11>0.3355</PDBx:U11>
         <PDBx:U12>0.0782</PDBx:U12>
         <PDBx:U13>0.0625</PDBx:U13>
         <PDBx:U22>0.2502</PDBx:U22>
         <PDBx:U23>-0.0014</PDBx:U23>
         <PDBx:U33>0.3247</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="956">
         <PDBx:U11>0.3314</PDBx:U11>
         <PDBx:U12>0.0152</PDBx:U12>
         <PDBx:U13>0.0304</PDBx:U13>
         <PDBx:U22>0.2786</PDBx:U22>
         <PDBx:U23>0.0214</PDBx:U23>
         <PDBx:U33>0.3322</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="957">
         <PDBx:U11>0.4692</PDBx:U11>
         <PDBx:U12>-0.0194</PDBx:U12>
         <PDBx:U13>0.0442</PDBx:U13>
         <PDBx:U22>0.2816</PDBx:U22>
         <PDBx:U23>0.0104</PDBx:U23>
         <PDBx:U33>0.2697</PDBx:U33>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.0472</PDBx:U23>
         <PDBx:U33>0.2669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="974">
         <PDBx:U11>0.2616</PDBx:U11>
         <PDBx:U12>0.0245</PDBx:U12>
         <PDBx:U13>0.0522</PDBx:U13>
         <PDBx:U22>0.3144</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.2734</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="975">
         <PDBx:U11>0.2919</PDBx:U11>
         <PDBx:U12>0.0351</PDBx:U12>
         <PDBx:U13>0.0415</PDBx:U13>
         <PDBx:U22>0.2943</PDBx:U22>
         <PDBx:U23>0.0130</PDBx:U23>
         <PDBx:U33>0.2535</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="976">
         <PDBx:U11>0.2560</PDBx:U11>
         <PDBx:U12>-0.0098</PDBx:U12>
         <PDBx:U13>0.0323</PDBx:U13>
         <PDBx:U22>0.3029</PDBx:U22>
         <PDBx:U23>0.0321</PDBx:U23>
         <PDBx:U33>0.2401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="977">
         <PDBx:U11>0.3036</PDBx:U11>
         <PDBx:U12>0.0385</PDBx:U12>
         <PDBx:U13>0.0096</PDBx:U13>
         <PDBx:U22>0.3399</PDBx:U22>
         <PDBx:U23>0.0215</PDBx:U23>
         <PDBx:U33>0.2588</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="978">
         <PDBx:U11>0.3548</PDBx:U11>
         <PDBx:U12>0.0854</PDBx:U12>
         <PDBx:U13>0.0333</PDBx:U13>
         <PDBx:U22>0.3365</PDBx:U22>
         <PDBx:U23>-0.0620</PDBx:U23>
         <PDBx:U33>0.2999</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="979">
         <PDBx:U11>0.3453</PDBx:U11>
         <PDBx:U12>0.1526</PDBx:U12>
         <PDBx:U13>0.0699</PDBx:U13>
         <PDBx:U22>0.4193</PDBx:U22>
         <PDBx:U23>-0.0486</PDBx:U23>
         <PDBx:U33>0.3289</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="980">
         <PDBx:U11>0.5795</PDBx:U11>
         <PDBx:U12>0.1394</PDBx:U12>
         <PDBx:U13>0.1565</PDBx:U13>
         <PDBx:U22>0.5773</PDBx:U22>
         <PDBx:U23>0.0335</PDBx:U23>
         <PDBx:U33>0.3895</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="981">
         <PDBx:U11>0.8347</PDBx:U11>
         <PDBx:U12>0.0991</PDBx:U12>
         <PDBx:U13>0.1220</PDBx:U13>
         <PDBx:U22>0.5322</PDBx:U22>
         <PDBx:U23>0.0211</PDBx:U23>
         <PDBx:U33>0.6084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="982">
         <PDBx:U11>0.6613</PDBx:U11>
         <PDBx:U12>0.1024</PDBx:U12>
         <PDBx:U13>0.2414</PDBx:U13>
         <PDBx:U22>0.7233</PDBx:U22>
         <PDBx:U23>0.0932</PDBx:U23>
         <PDBx:U33>0.5206</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="983">
         <PDBx:U11>0.2430</PDBx:U11>
         <PDBx:U12>0.0178</PDBx:U12>
         <PDBx:U13>0.0461</PDBx:U13>
         <PDBx:U22>0.2303</PDBx:U22>
         <PDBx:U23>0.0256</PDBx:U23>
         <PDBx:U33>0.2043</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="984">
         <PDBx:U11>0.2263</PDBx:U11>
         <PDBx:U12>-0.0003</PDBx:U12>
         <PDBx:U13>0.0212</PDBx:U13>
         <PDBx:U22>0.2342</PDBx:U22>
         <PDBx:U23>0.0279</PDBx:U23>
         <PDBx:U33>0.2419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="985">
         <PDBx:U11>0.2356</PDBx:U11>
         <PDBx:U12>-0.0020</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.2889</PDBx:U22>
         <PDBx:U23>0.0464</PDBx:U23>
         <PDBx:U33>0.2303</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="986">
         <PDBx:U11>0.2878</PDBx:U11>
         <PDBx:U12>-0.0544</PDBx:U12>
         <PDBx:U13>-0.0127</PDBx:U13>
         <PDBx:U22>0.2859</PDBx:U22>
         <PDBx:U23>0.0093</PDBx:U23>
         <PDBx:U33>0.2066</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="987">
         <PDBx:U11>0.1957</PDBx:U11>
         <PDBx:U12>0.0114</PDBx:U12>
         <PDBx:U13>0.0128</PDBx:U13>
         <PDBx:U22>0.2226</PDBx:U22>
         <PDBx:U23>0.0178</PDBx:U23>
         <PDBx:U33>0.2308</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="988">
         <PDBx:U11>0.2066</PDBx:U11>
         <PDBx:U12>0.0044</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.2425</PDBx:U22>
         <PDBx:U23>0.0047</PDBx:U23>
         <PDBx:U33>0.2358</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="989">
         <PDBx:U11>0.2585</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0151</PDBx:U13>
         <PDBx:U22>0.2519</PDBx:U22>
         <PDBx:U23>0.0163</PDBx:U23>
         <PDBx:U33>0.2513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="990">
         <PDBx:U11>0.2013</PDBx:U11>
         <PDBx:U12>0.0066</PDBx:U12>
         <PDBx:U13>0.0304</PDBx:U13>
         <PDBx:U22>0.3221</PDBx:U22>
         <PDBx:U23>-0.0190</PDBx:U23>
         <PDBx:U33>0.2841</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="991">
         <PDBx:U11>0.2750</PDBx:U11>
         <PDBx:U12>0.0146</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.2825</PDBx:U22>
         <PDBx:U23>0.0331</PDBx:U23>
         <PDBx:U33>0.2910</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="992">
         <PDBx:U11>0.2647</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>-0.0295</PDBx:U13>
         <PDBx:U22>0.2291</PDBx:U22>
         <PDBx:U23>-0.0013</PDBx:U23>
         <PDBx:U33>0.2449</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="993">
         <PDBx:U11>0.2747</PDBx:U11>
         <PDBx:U12>0.0060</PDBx:U12>
         <PDBx:U13>-0.0033</PDBx:U13>
         <PDBx:U22>0.2352</PDBx:U22>
         <PDBx:U23>0.0040</PDBx:U23>
         <PDBx:U33>0.2711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="994">
         <PDBx:U11>0.2046</PDBx:U11>
         <PDBx:U12>0.0140</PDBx:U12>
         <PDBx:U13>0.0265</PDBx:U13>
         <PDBx:U22>0.1850</PDBx:U22>
         <PDBx:U23>0.0109</PDBx:U23>
         <PDBx:U33>0.2136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="995">
         <PDBx:U11>0.1913</PDBx:U11>
         <PDBx:U12>0.0050</PDBx:U12>
         <PDBx:U13>0.0194</PDBx:U13>
         <PDBx:U22>0.2154</PDBx:U22>
         <PDBx:U23>0.0118</PDBx:U23>
         <PDBx:U33>0.1565</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="996">
         <PDBx:U11>0.2363</PDBx:U11>
         <PDBx:U12>0.0020</PDBx:U12>
         <PDBx:U13>0.0307</PDBx:U13>
         <PDBx:U22>0.1840</PDBx:U22>
         <PDBx:U23>0.0060</PDBx:U23>
         <PDBx:U33>0.1893</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="997">
         <PDBx:U11>0.2345</PDBx:U11>
         <PDBx:U12>0.0143</PDBx:U12>
         <PDBx:U13>0.0296</PDBx:U13>
         <PDBx:U22>0.2050</PDBx:U22>
         <PDBx:U23>0.0166</PDBx:U23>
         <PDBx:U33>0.2149</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="998">
         <PDBx:U11>0.2371</PDBx:U11>
         <PDBx:U12>0.0088</PDBx:U12>
         <PDBx:U13>-0.0074</PDBx:U13>
         <PDBx:U22>0.1975</PDBx:U22>
         <PDBx:U23>-0.0231</PDBx:U23>
         <PDBx:U33>0.2079</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="999">
         <PDBx:U11>0.2441</PDBx:U11>
         <PDBx:U12>0.0031</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.2026</PDBx:U22>
         <PDBx:U23>-0.0271</PDBx:U23>
         <PDBx:U33>0.2248</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1000">
         <PDBx:U11>0.2452</PDBx:U11>
         <PDBx:U12>-0.0094</PDBx:U12>
         <PDBx:U13>-0.0125</PDBx:U13>
         <PDBx:U22>0.2090</PDBx:U22>
         <PDBx:U23>0.0190</PDBx:U23>
         <PDBx:U33>0.2074</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1001">
         <PDBx:U11>0.2965</PDBx:U11>
         <PDBx:U12>0.0160</PDBx:U12>
         <PDBx:U13>-0.0296</PDBx:U13>
         <PDBx:U22>0.2430</PDBx:U22>
         <PDBx:U23>-0.0203</PDBx:U23>
         <PDBx:U33>0.2353</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1002">
         <PDBx:U11>0.2157</PDBx:U11>
         <PDBx:U12>0.0060</PDBx:U12>
         <PDBx:U13>0.0415</PDBx:U13>
         <PDBx:U22>0.2032</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.1834</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1003">
         <PDBx:U11>0.2024</PDBx:U11>
         <PDBx:U12>0.0128</PDBx:U12>
         <PDBx:U13>0.0236</PDBx:U13>
         <PDBx:U22>0.2063</PDBx:U22>
         <PDBx:U23>0.0091</PDBx:U23>
         <PDBx:U33>0.1767</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1004">
         <PDBx:U11>0.1928</PDBx:U11>
         <PDBx:U12>0.0219</PDBx:U12>
         <PDBx:U13>0.0157</PDBx:U13>
         <PDBx:U22>0.1902</PDBx:U22>
         <PDBx:U23>0.0059</PDBx:U23>
         <PDBx:U33>0.2098</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1005">
         <PDBx:U11>0.2254</PDBx:U11>
         <PDBx:U12>0.0143</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.1943</PDBx:U22>
         <PDBx:U23>0.0091</PDBx:U23>
         <PDBx:U33>0.2121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1006">
         <PDBx:U11>0.2223</PDBx:U11>
         <PDBx:U12>0.0054</PDBx:U12>
         <PDBx:U13>0.0056</PDBx:U13>
         <PDBx:U22>0.1992</PDBx:U22>
         <PDBx:U23>0.0103</PDBx:U23>
         <PDBx:U33>0.1719</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1007">
         <PDBx:U11>0.2333</PDBx:U11>
         <PDBx:U12>0.0277</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.2292</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1992</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1008">
         <PDBx:U11>0.2212</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>0.0213</PDBx:U13>
         <PDBx:U22>0.1932</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1949</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1009">
         <PDBx:U11>0.2468</PDBx:U11>
         <PDBx:U12>0.0116</PDBx:U12>
         <PDBx:U13>0.0189</PDBx:U13>
         <PDBx:U22>0.1972</PDBx:U22>
         <PDBx:U23>-0.0151</PDBx:U23>
         <PDBx:U33>0.2258</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1010">
         <PDBx:U11>0.2597</PDBx:U11>
         <PDBx:U12>0.0049</PDBx:U12>
         <PDBx:U13>0.0391</PDBx:U13>
         <PDBx:U22>0.1855</PDBx:U22>
         <PDBx:U23>0.0132</PDBx:U23>
         <PDBx:U33>0.2175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1011">
         <PDBx:U11>0.2110</PDBx:U11>
         <PDBx:U12>0.0099</PDBx:U12>
         <PDBx:U13>0.0292</PDBx:U13>
         <PDBx:U22>0.1983</PDBx:U22>
         <PDBx:U23>-0.0152</PDBx:U23>
         <PDBx:U33>0.2462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1012">
         <PDBx:U11>0.2166</PDBx:U11>
         <PDBx:U12>0.0032</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.1895</PDBx:U22>
         <PDBx:U23>-0.0152</PDBx:U23>
         <PDBx:U33>0.1896</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1013">
         <PDBx:U11>0.2114</PDBx:U11>
         <PDBx:U12>-0.0090</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.2174</PDBx:U22>
         <PDBx:U23>0.0047</PDBx:U23>
         <PDBx:U33>0.1748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1014">
         <PDBx:U11>0.2128</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>0.0166</PDBx:U13>
         <PDBx:U22>0.2098</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.2039</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1015">
         <PDBx:U11>0.2345</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>-0.0227</PDBx:U13>
         <PDBx:U22>0.2156</PDBx:U22>
         <PDBx:U23>-0.0200</PDBx:U23>
         <PDBx:U33>0.1936</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1016">
         <PDBx:U11>0.2191</PDBx:U11>
         <PDBx:U12>0.0375</PDBx:U12>
         <PDBx:U13>0.0174</PDBx:U13>
         <PDBx:U22>0.2087</PDBx:U22>
         <PDBx:U23>0.0081</PDBx:U23>
         <PDBx:U33>0.1644</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1017">
         <PDBx:U11>0.2456</PDBx:U11>
         <PDBx:U12>0.0562</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.2673</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.1746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1018">
         <PDBx:U11>0.2371</PDBx:U11>
         <PDBx:U12>0.0190</PDBx:U12>
         <PDBx:U13>-0.0022</PDBx:U13>
         <PDBx:U22>0.2665</PDBx:U22>
         <PDBx:U23>0.0327</PDBx:U23>
         <PDBx:U33>0.1931</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1019">
         <PDBx:U11>0.2253</PDBx:U11>
         <PDBx:U12>0.0105</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.2719</PDBx:U22>
         <PDBx:U23>0.0196</PDBx:U23>
         <PDBx:U33>0.2243</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1020">
         <PDBx:U11>0.2909</PDBx:U11>
         <PDBx:U12>-0.0203</PDBx:U12>
         <PDBx:U13>0.0182</PDBx:U13>
         <PDBx:U22>0.2140</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.2680</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1021">
         <PDBx:U11>0.3018</PDBx:U11>
         <PDBx:U12>-0.0287</PDBx:U12>
         <PDBx:U13>-0.0422</PDBx:U13>
         <PDBx:U22>0.2315</PDBx:U22>
         <PDBx:U23>0.0172</PDBx:U23>
         <PDBx:U33>0.2240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1022">
         <PDBx:U11>0.2935</PDBx:U11>
         <PDBx:U12>-0.0108</PDBx:U12>
         <PDBx:U13>-0.0239</PDBx:U13>
         <PDBx:U22>0.2751</PDBx:U22>
         <PDBx:U23>0.0309</PDBx:U23>
         <PDBx:U33>0.2333</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1023">
         <PDBx:U11>0.2137</PDBx:U11>
         <PDBx:U12>0.0107</PDBx:U12>
         <PDBx:U13>0.0179</PDBx:U13>
         <PDBx:U22>0.1835</PDBx:U22>
         <PDBx:U23>0.0133</PDBx:U23>
         <PDBx:U33>0.1830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1024">
         <PDBx:U11>0.1624</PDBx:U11>
         <PDBx:U12>-0.0029</PDBx:U12>
         <PDBx:U13>-0.0077</PDBx:U13>
         <PDBx:U22>0.1615</PDBx:U22>
         <PDBx:U23>0.0036</PDBx:U23>
         <PDBx:U33>0.1690</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1025">
         <PDBx:U11>0.1791</PDBx:U11>
         <PDBx:U12>0.0073</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.1806</PDBx:U22>
         <PDBx:U23>0.0224</PDBx:U23>
         <PDBx:U33>0.1666</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1026">
         <PDBx:U11>0.2034</PDBx:U11>
         <PDBx:U12>0.0133</PDBx:U12>
         <PDBx:U13>-0.0129</PDBx:U13>
         <PDBx:U22>0.2083</PDBx:U22>
         <PDBx:U23>0.0092</PDBx:U23>
         <PDBx:U33>0.1903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1027">
         <PDBx:U11>0.2058</PDBx:U11>
         <PDBx:U12>0.0505</PDBx:U12>
         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.2108</PDBx:U22>
         <PDBx:U23>0.0247</PDBx:U23>
         <PDBx:U33>0.1769</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1028">
         <PDBx:U11>0.2178</PDBx:U11>
         <PDBx:U12>0.0305</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.1952</PDBx:U22>
         <PDBx:U23>0.0080</PDBx:U23>
         <PDBx:U33>0.1526</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1029">
         <PDBx:U11>0.2141</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>-0.0160</PDBx:U13>
         <PDBx:U22>0.1994</PDBx:U22>
         <PDBx:U23>0.0137</PDBx:U23>
         <PDBx:U33>0.2311</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1030">
         <PDBx:U11>0.2221</PDBx:U11>
         <PDBx:U12>0.0505</PDBx:U12>
         <PDBx:U13>-0.0283</PDBx:U13>
         <PDBx:U22>0.2298</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.2194</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1031">
         <PDBx:U11>0.1740</PDBx:U11>
         <PDBx:U12>-0.0103</PDBx:U12>
         <PDBx:U13>-0.0202</PDBx:U13>
         <PDBx:U22>0.1571</PDBx:U22>
         <PDBx:U23>0.0120</PDBx:U23>
         <PDBx:U33>0.2008</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1032">
         <PDBx:U11>0.1822</PDBx:U11>
         <PDBx:U12>0.0224</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.1918</PDBx:U22>
         <PDBx:U23>0.0161</PDBx:U23>
         <PDBx:U33>0.1559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1033">
         <PDBx:U11>0.1734</PDBx:U11>
         <PDBx:U12>-0.0083</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.1744</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.1839</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1034">
         <PDBx:U11>0.1827</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>-0.0188</PDBx:U13>
         <PDBx:U22>0.1698</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.1940</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1035">
         <PDBx:U11>0.1645</PDBx:U11>
         <PDBx:U12>0.0314</PDBx:U12>
         <PDBx:U13>-0.0174</PDBx:U13>
         <PDBx:U22>0.1877</PDBx:U22>
         <PDBx:U23>0.0077</PDBx:U23>
         <PDBx:U33>0.1733</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1036">
         <PDBx:U11>0.1738</PDBx:U11>
         <PDBx:U12>0.0087</PDBx:U12>
         <PDBx:U13>-0.0170</PDBx:U13>
         <PDBx:U22>0.1756</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.1777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1037">
         <PDBx:U11>0.1885</PDBx:U11>
         <PDBx:U12>-0.0178</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.1784</PDBx:U22>
         <PDBx:U23>-0.0225</PDBx:U23>
         <PDBx:U33>0.1770</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1038">
         <PDBx:U11>0.1940</PDBx:U11>
         <PDBx:U12>0.0316</PDBx:U12>
         <PDBx:U13>0.0179</PDBx:U13>
         <PDBx:U22>0.1819</PDBx:U22>
         <PDBx:U23>0.0097</PDBx:U23>
         <PDBx:U33>0.2250</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1039">
         <PDBx:U11>0.1892</PDBx:U11>
         <PDBx:U12>-0.0026</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.1678</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.1664</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1040">
         <PDBx:U11>0.1821</PDBx:U11>
         <PDBx:U12>0.0028</PDBx:U12>
         <PDBx:U13>0.0127</PDBx:U13>
         <PDBx:U22>0.1777</PDBx:U22>
         <PDBx:U23>0.0019</PDBx:U23>
         <PDBx:U33>0.1777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1041">
         <PDBx:U11>0.2306</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.1898</PDBx:U22>
         <PDBx:U23>0.0057</PDBx:U23>
         <PDBx:U33>0.1758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1042">
         <PDBx:U11>0.1945</PDBx:U11>
         <PDBx:U12>-0.0151</PDBx:U12>
         <PDBx:U13>0.0079</PDBx:U13>
         <PDBx:U22>0.1778</PDBx:U22>
         <PDBx:U23>-0.0069</PDBx:U23>
         <PDBx:U33>0.1878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1043">
         <PDBx:U11>0.1818</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>-0.0065</PDBx:U13>
         <PDBx:U22>0.1729</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.1890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1044">
         <PDBx:U11>0.1813</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>0.0054</PDBx:U13>
         <PDBx:U22>0.1636</PDBx:U22>
         <PDBx:U23>0.0046</PDBx:U23>
         <PDBx:U33>0.1549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1045">
         <PDBx:U11>0.2444</PDBx:U11>
         <PDBx:U12>0.0055</PDBx:U12>
         <PDBx:U13>0.0179</PDBx:U13>
         <PDBx:U22>0.1556</PDBx:U22>
         <PDBx:U23>0.0150</PDBx:U23>
         <PDBx:U33>0.1411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1046">
         <PDBx:U11>0.2200</PDBx:U11>
         <PDBx:U12>0.0059</PDBx:U12>
         <PDBx:U13>-0.0077</PDBx:U13>
         <PDBx:U22>0.1828</PDBx:U22>
         <PDBx:U23>0.0058</PDBx:U23>
         <PDBx:U33>0.1615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1047">
         <PDBx:U11>0.2511</PDBx:U11>
         <PDBx:U12>0.0128</PDBx:U12>
         <PDBx:U13>-0.0211</PDBx:U13>
         <PDBx:U22>0.1696</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.2045</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1048">
         <PDBx:U11>0.2475</PDBx:U11>
         <PDBx:U12>-0.0528</PDBx:U12>
         <PDBx:U13>0.0085</PDBx:U13>
         <PDBx:U22>0.1630</PDBx:U22>
         <PDBx:U23>0.0069</PDBx:U23>
         <PDBx:U33>0.1315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1049">
         <PDBx:U11>0.1986</PDBx:U11>
         <PDBx:U12>0.0058</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1635</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.1926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1050">
         <PDBx:U11>0.2054</PDBx:U11>
         <PDBx:U12>0.0057</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.1707</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.2003</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1051">
         <PDBx:U11>0.2402</PDBx:U11>
         <PDBx:U12>0.0119</PDBx:U12>
         <PDBx:U13>0.0209</PDBx:U13>
         <PDBx:U22>0.1919</PDBx:U22>
         <PDBx:U23>0.0263</PDBx:U23>
         <PDBx:U33>0.1878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1052">
         <PDBx:U11>0.2888</PDBx:U11>
         <PDBx:U12>0.0303</PDBx:U12>
         <PDBx:U13>-0.0041</PDBx:U13>
         <PDBx:U22>0.1996</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.2484</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1053">
         <PDBx:U11>0.1957</PDBx:U11>
         <PDBx:U12>0.0228</PDBx:U12>
         <PDBx:U13>-0.0058</PDBx:U13>
         <PDBx:U22>0.2072</PDBx:U22>
         <PDBx:U23>-0.0002</PDBx:U23>
         <PDBx:U33>0.1825</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1054">
         <PDBx:U11>0.2142</PDBx:U11>
         <PDBx:U12>0.0366</PDBx:U12>
         <PDBx:U13>-0.0070</PDBx:U13>
         <PDBx:U22>0.1963</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.1785</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1055">
         <PDBx:U11>0.2120</PDBx:U11>
         <PDBx:U12>0.0273</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.1790</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.1860</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1056">
         <PDBx:U11>0.2360</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.1772</PDBx:U22>
         <PDBx:U23>-0.0152</PDBx:U23>
         <PDBx:U33>0.1895</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1057">
         <PDBx:U11>0.2202</PDBx:U11>
         <PDBx:U12>0.0073</PDBx:U12>
         <PDBx:U13>-0.0057</PDBx:U13>
         <PDBx:U22>0.1627</PDBx:U22>
         <PDBx:U23>0.0064</PDBx:U23>
         <PDBx:U33>0.1732</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1058">
         <PDBx:U11>0.2418</PDBx:U11>
         <PDBx:U12>-0.0138</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.2161</PDBx:U22>
         <PDBx:U23>0.0273</PDBx:U23>
         <PDBx:U33>0.1791</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1059">
         <PDBx:U11>0.2410</PDBx:U11>
         <PDBx:U12>-0.0166</PDBx:U12>
         <PDBx:U13>-0.0044</PDBx:U13>
         <PDBx:U22>0.2006</PDBx:U22>
         <PDBx:U23>0.0038</PDBx:U23>
         <PDBx:U33>0.1795</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1060">
         <PDBx:U11>0.1970</PDBx:U11>
         <PDBx:U12>-0.0221</PDBx:U12>
         <PDBx:U13>-0.0062</PDBx:U13>
         <PDBx:U22>0.1918</PDBx:U22>
         <PDBx:U23>0.0124</PDBx:U23>
         <PDBx:U33>0.1736</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1061">
         <PDBx:U11>0.2156</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.1651</PDBx:U22>
         <PDBx:U23>-0.0147</PDBx:U23>
         <PDBx:U33>0.1706</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1062">
         <PDBx:U11>0.2299</PDBx:U11>
         <PDBx:U12>-0.0210</PDBx:U12>
         <PDBx:U13>-0.0100</PDBx:U13>
         <PDBx:U22>0.2684</PDBx:U22>
         <PDBx:U23>0.0094</PDBx:U23>
         <PDBx:U33>0.1911</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1063">
         <PDBx:U11>0.2633</PDBx:U11>
         <PDBx:U12>-0.0766</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.2746</PDBx:U22>
         <PDBx:U23>0.0397</PDBx:U23>
         <PDBx:U33>0.2175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1064">
         <PDBx:U11>0.2640</PDBx:U11>
         <PDBx:U12>-0.0068</PDBx:U12>
         <PDBx:U13>-0.0178</PDBx:U13>
         <PDBx:U22>0.1974</PDBx:U22>
         <PDBx:U23>-0.0107</PDBx:U23>
         <PDBx:U33>0.1625</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1065">
         <PDBx:U11>0.2178</PDBx:U11>
         <PDBx:U12>0.0137</PDBx:U12>
         <PDBx:U13>-0.0022</PDBx:U13>
         <PDBx:U22>0.1818</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.1777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1066">
         <PDBx:U11>0.2830</PDBx:U11>
         <PDBx:U12>0.0559</PDBx:U12>
         <PDBx:U13>-0.0058</PDBx:U13>
         <PDBx:U22>0.2267</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.2019</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1067">
         <PDBx:U11>0.2427</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>-0.0194</PDBx:U13>
         <PDBx:U22>0.1884</PDBx:U22>
         <PDBx:U23>-0.0235</PDBx:U23>
         <PDBx:U33>0.1831</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1068">
         <PDBx:U11>0.2279</PDBx:U11>
         <PDBx:U12>-0.0097</PDBx:U12>
         <PDBx:U13>-0.0173</PDBx:U13>
         <PDBx:U22>0.1649</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.1917</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1069">
         <PDBx:U11>0.1811</PDBx:U11>
         <PDBx:U12>0.0137</PDBx:U12>
         <PDBx:U13>-0.0229</PDBx:U13>
         <PDBx:U22>0.1592</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.1951</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1070">
         <PDBx:U11>0.2099</PDBx:U11>
         <PDBx:U12>-0.0146</PDBx:U12>
         <PDBx:U13>0.0100</PDBx:U13>
         <PDBx:U22>0.1884</PDBx:U22>
         <PDBx:U23>0.0153</PDBx:U23>
         <PDBx:U33>0.1645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1071">
         <PDBx:U11>0.2186</PDBx:U11>
         <PDBx:U12>-0.0031</PDBx:U12>
         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.1951</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.1864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1072">
         <PDBx:U11>0.2139</PDBx:U11>
         <PDBx:U12>-0.0086</PDBx:U12>
         <PDBx:U13>-0.0138</PDBx:U13>
         <PDBx:U22>0.1573</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.1648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1073">
         <PDBx:U11>0.2094</PDBx:U11>
         <PDBx:U12>0.0010</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.1885</PDBx:U22>
         <PDBx:U23>-0.0189</PDBx:U23>
         <PDBx:U33>0.2187</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1074">
         <PDBx:U11>0.2084</PDBx:U11>
         <PDBx:U12>-0.0002</PDBx:U12>
         <PDBx:U13>-0.0162</PDBx:U13>
         <PDBx:U22>0.1531</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.1812</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1075">
         <PDBx:U11>0.2880</PDBx:U11>
         <PDBx:U12>0.0021</PDBx:U12>
         <PDBx:U13>-0.0057</PDBx:U13>
         <PDBx:U22>0.1562</PDBx:U22>
         <PDBx:U23>0.0036</PDBx:U23>
         <PDBx:U33>0.1853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1076">
         <PDBx:U11>0.2111</PDBx:U11>
         <PDBx:U12>-0.0027</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.1852</PDBx:U22>
         <PDBx:U23>-0.0145</PDBx:U23>
         <PDBx:U33>0.2079</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1077">
         <PDBx:U11>0.2105</PDBx:U11>
         <PDBx:U12>-0.0010</PDBx:U12>
         <PDBx:U13>-0.0157</PDBx:U13>
         <PDBx:U22>0.1620</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.1863</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1078">
         <PDBx:U11>0.2530</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>-0.0252</PDBx:U13>
         <PDBx:U22>0.1565</PDBx:U22>
         <PDBx:U23>0.0169</PDBx:U23>
         <PDBx:U33>0.1973</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1079">
         <PDBx:U11>0.2512</PDBx:U11>
         <PDBx:U12>-0.0039</PDBx:U12>
         <PDBx:U13>-0.0219</PDBx:U13>
         <PDBx:U22>0.1980</PDBx:U22>
         <PDBx:U23>0.0428</PDBx:U23>
         <PDBx:U33>0.1915</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1080">
         <PDBx:U11>0.2611</PDBx:U11>
         <PDBx:U12>0.0006</PDBx:U12>
         <PDBx:U13>0.0122</PDBx:U13>
         <PDBx:U22>0.1775</PDBx:U22>
         <PDBx:U23>0.0260</PDBx:U23>
         <PDBx:U33>0.1978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1081">
         <PDBx:U11>0.2999</PDBx:U11>
         <PDBx:U12>0.0299</PDBx:U12>
         <PDBx:U13>0.0160</PDBx:U13>
         <PDBx:U22>0.3361</PDBx:U22>
         <PDBx:U23>0.0205</PDBx:U23>
         <PDBx:U33>0.2818</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1082">
         <PDBx:U11>0.2149</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>-0.0088</PDBx:U13>
         <PDBx:U22>0.1745</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.1924</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1083">
         <PDBx:U11>0.2365</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>0.0005</PDBx:U13>
         <PDBx:U22>0.1763</PDBx:U22>
         <PDBx:U23>0.0224</PDBx:U23>
         <PDBx:U33>0.1667</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1084">
         <PDBx:U11>0.2167</PDBx:U11>
         <PDBx:U12>0.0084</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.1851</PDBx:U22>
         <PDBx:U23>0.0039</PDBx:U23>
         <PDBx:U33>0.1895</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1085">
         <PDBx:U11>0.2482</PDBx:U11>
         <PDBx:U12>0.0048</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>0.1615</PDBx:U22>
         <PDBx:U23>0.0023</PDBx:U23>
         <PDBx:U33>0.2133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1086">
         <PDBx:U11>0.2489</PDBx:U11>
         <PDBx:U12>-0.0272</PDBx:U12>
         <PDBx:U13>-0.0100</PDBx:U13>
         <PDBx:U22>0.1790</PDBx:U22>
         <PDBx:U23>0.0198</PDBx:U23>
         <PDBx:U33>0.1603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1087">
         <PDBx:U11>0.2364</PDBx:U11>
         <PDBx:U12>-0.0209</PDBx:U12>
         <PDBx:U13>-0.0254</PDBx:U13>
         <PDBx:U22>0.1991</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.1765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1088">
         <PDBx:U11>0.1914</PDBx:U11>
         <PDBx:U12>-0.0030</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.1633</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.2019</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1089">
         <PDBx:U11>0.2517</PDBx:U11>
         <PDBx:U12>-0.0296</PDBx:U12>
         <PDBx:U13>-0.0201</PDBx:U13>
         <PDBx:U22>0.1491</PDBx:U22>
         <PDBx:U23>0.0073</PDBx:U23>
         <PDBx:U33>0.1868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>530</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1090">
         <PDBx:U11>0.2218</PDBx:U11>
         <PDBx:U12>-0.0422</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.1880</PDBx:U22>
         <PDBx:U23>-0.0247</PDBx:U23>
         <PDBx:U33>0.2046</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>530</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1091">
         <PDBx:U11>0.2709</PDBx:U11>
         <PDBx:U12>-0.0180</PDBx:U12>
         <PDBx:U13>0.0085</PDBx:U13>
         <PDBx:U22>0.2011</PDBx:U22>
         <PDBx:U23>0.0083</PDBx:U23>
         <PDBx:U33>0.2061</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>530</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1092">
         <PDBx:U11>0.2584</PDBx:U11>
         <PDBx:U12>-0.0246</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.1899</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.1922</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>530</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1093">
         <PDBx:U11>0.2351</PDBx:U11>
         <PDBx:U12>0.0036</PDBx:U12>
         <PDBx:U13>0.0189</PDBx:U13>
         <PDBx:U22>0.2035</PDBx:U22>
         <PDBx:U23>0.0229</PDBx:U23>
         <PDBx:U33>0.1879</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>530</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1094">
         <PDBx:U11>0.2518</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.1764</PDBx:U22>
         <PDBx:U23>0.0004</PDBx:U23>
         <PDBx:U33>0.2183</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>530</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1095">
         <PDBx:U11>0.2550</PDBx:U11>
         <PDBx:U12>-0.0127</PDBx:U12>
         <PDBx:U13>-0.0219</PDBx:U13>
         <PDBx:U22>0.2129</PDBx:U22>
         <PDBx:U23>0.0072</PDBx:U23>
         <PDBx:U33>0.2136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>530</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1096">
         <PDBx:U11>0.2795</PDBx:U11>
         <PDBx:U12>-0.0270</PDBx:U12>
         <PDBx:U13>0.0147</PDBx:U13>
         <PDBx:U22>0.2224</PDBx:U22>
         <PDBx:U23>0.0160</PDBx:U23>
         <PDBx:U33>0.2544</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>530</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1097">
         <PDBx:U11>0.2901</PDBx:U11>
         <PDBx:U12>-0.0329</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.2115</PDBx:U22>
         <PDBx:U23>-0.0379</PDBx:U23>
         <PDBx:U33>0.2327</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>531</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1098">
         <PDBx:U11>0.3165</PDBx:U11>
         <PDBx:U12>-0.0390</PDBx:U12>
         <PDBx:U13>-0.0334</PDBx:U13>
         <PDBx:U22>0.1828</PDBx:U22>
         <PDBx:U23>-0.0401</PDBx:U23>
         <PDBx:U33>0.2401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>531</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1099">
         <PDBx:U11>0.3039</PDBx:U11>
         <PDBx:U12>-0.0156</PDBx:U12>
         <PDBx:U13>0.0096</PDBx:U13>
         <PDBx:U22>0.2137</PDBx:U22>
         <PDBx:U23>-0.0057</PDBx:U23>
         <PDBx:U33>0.2288</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>531</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1100">
         <PDBx:U11>0.4121</PDBx:U11>
         <PDBx:U12>0.0021</PDBx:U12>
         <PDBx:U13>0.0133</PDBx:U13>
         <PDBx:U22>0.2654</PDBx:U22>
         <PDBx:U23>-0.0311</PDBx:U23>
         <PDBx:U33>0.2349</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>531</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1101">
         <PDBx:U11>0.4316</PDBx:U11>
         <PDBx:U12>-0.0422</PDBx:U12>
         <PDBx:U13>-0.0120</PDBx:U13>
         <PDBx:U22>0.1538</PDBx:U22>
         <PDBx:U23>-0.0324</PDBx:U23>
         <PDBx:U33>0.2972</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>531</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1102">
         <PDBx:U11>0.4639</PDBx:U11>
         <PDBx:U12>-0.1005</PDBx:U12>
         <PDBx:U13>0.0134</PDBx:U13>
         <PDBx:U22>0.3695</PDBx:U22>
         <PDBx:U23>-0.0211</PDBx:U23>
         <PDBx:U33>0.4178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>531</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1103">
         <PDBx:U11>0.4524</PDBx:U11>
         <PDBx:U12>-0.0893</PDBx:U12>
         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.3753</PDBx:U22>
         <PDBx:U23>-0.0092</PDBx:U23>
         <PDBx:U33>0.4264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>531</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1104">
         <PDBx:U11>0.6509</PDBx:U11>
         <PDBx:U12>-0.2230</PDBx:U12>
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         <PDBx:U22>0.6569</PDBx:U22>
         <PDBx:U23>-0.1342</PDBx:U23>
         <PDBx:U33>0.4875</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>531</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1105">
         <PDBx:U11>0.2921</PDBx:U11>
         <PDBx:U12>-0.0066</PDBx:U12>
         <PDBx:U13>-0.0200</PDBx:U13>
         <PDBx:U22>0.2240</PDBx:U22>
         <PDBx:U23>-0.0285</PDBx:U23>
         <PDBx:U33>0.2111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1106">
         <PDBx:U11>0.3154</PDBx:U11>
         <PDBx:U12>0.0110</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.2129</PDBx:U22>
         <PDBx:U23>-0.0146</PDBx:U23>
         <PDBx:U33>0.2176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1107">
         <PDBx:U11>0.2915</PDBx:U11>
         <PDBx:U12>0.0026</PDBx:U12>
         <PDBx:U13>-0.0130</PDBx:U13>
         <PDBx:U22>0.2301</PDBx:U22>
         <PDBx:U23>-0.0499</PDBx:U23>
         <PDBx:U33>0.2077</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1108">
         <PDBx:U11>0.3526</PDBx:U11>
         <PDBx:U12>-0.0082</PDBx:U12>
         <PDBx:U13>-0.0610</PDBx:U13>
         <PDBx:U22>0.2406</PDBx:U22>
         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.2587</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1109">
         <PDBx:U11>0.2624</PDBx:U11>
         <PDBx:U12>-0.0236</PDBx:U12>
         <PDBx:U13>-0.0463</PDBx:U13>
         <PDBx:U22>0.2892</PDBx:U22>
         <PDBx:U23>-0.0085</PDBx:U23>
         <PDBx:U33>0.3715</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1110">
         <PDBx:U11>0.4124</PDBx:U11>
         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>-0.0473</PDBx:U13>
         <PDBx:U22>0.3272</PDBx:U22>
         <PDBx:U23>-0.0171</PDBx:U23>
         <PDBx:U33>0.4109</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1111">
         <PDBx:U11>0.5301</PDBx:U11>
         <PDBx:U12>0.0175</PDBx:U12>
         <PDBx:U13>-0.0527</PDBx:U13>
         <PDBx:U22>0.3266</PDBx:U22>
         <PDBx:U23>-0.0237</PDBx:U23>
         <PDBx:U33>0.3984</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1112">
         <PDBx:U11>0.6279</PDBx:U11>
         <PDBx:U12>0.0109</PDBx:U12>
         <PDBx:U13>-0.1858</PDBx:U13>
         <PDBx:U22>0.4726</PDBx:U22>
         <PDBx:U23>-0.0422</PDBx:U23>
         <PDBx:U33>0.4702</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1113">
         <PDBx:U11>0.4419</PDBx:U11>
         <PDBx:U12>-0.0407</PDBx:U12>
         <PDBx:U13>-0.1759</PDBx:U13>
         <PDBx:U22>0.3507</PDBx:U22>
         <PDBx:U23>-0.0395</PDBx:U23>
         <PDBx:U33>0.5621</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1114">
         <PDBx:U11>0.2655</PDBx:U11>
         <PDBx:U12>-0.0277</PDBx:U12>
         <PDBx:U13>0.0182</PDBx:U13>
         <PDBx:U22>0.2160</PDBx:U22>
         <PDBx:U23>-0.0291</PDBx:U23>
         <PDBx:U33>0.1933</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1115">
         <PDBx:U11>0.3336</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>0.0176</PDBx:U13>
         <PDBx:U22>0.1747</PDBx:U22>
         <PDBx:U23>-0.0152</PDBx:U23>
         <PDBx:U33>0.1993</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1116">
         <PDBx:U11>0.2728</PDBx:U11>
         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>0.0212</PDBx:U13>
         <PDBx:U22>0.2256</PDBx:U22>
         <PDBx:U23>0.0090</PDBx:U23>
         <PDBx:U33>0.2144</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1117">
         <PDBx:U11>0.2840</PDBx:U11>
         <PDBx:U12>-0.0124</PDBx:U12>
         <PDBx:U13>0.0177</PDBx:U13>
         <PDBx:U22>0.2230</PDBx:U22>
         <PDBx:U23>0.0135</PDBx:U23>
         <PDBx:U33>0.2631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2646</PDBx:U11>
         <PDBx:U12>-0.0279</PDBx:U12>
         <PDBx:U13>0.0123</PDBx:U13>
         <PDBx:U22>0.2145</PDBx:U22>
         <PDBx:U23>-0.0211</PDBx:U23>
         <PDBx:U33>0.1837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1119">
         <PDBx:U11>0.2284</PDBx:U11>
         <PDBx:U12>-0.0433</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.2023</PDBx:U22>
         <PDBx:U23>-0.0084</PDBx:U23>
         <PDBx:U33>0.1760</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1120">
         <PDBx:U11>0.2120</PDBx:U11>
         <PDBx:U12>-0.0049</PDBx:U12>
         <PDBx:U13>-0.0043</PDBx:U13>
         <PDBx:U22>0.1616</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.1756</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1121">
         <PDBx:U11>0.1990</PDBx:U11>
         <PDBx:U12>-0.0058</PDBx:U12>
         <PDBx:U13>-0.0078</PDBx:U13>
         <PDBx:U22>0.1788</PDBx:U22>
         <PDBx:U23>-0.0092</PDBx:U23>
         <PDBx:U33>0.1827</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1122">
         <PDBx:U11>0.2032</PDBx:U11>
         <PDBx:U12>-0.0678</PDBx:U12>
         <PDBx:U13>0.0122</PDBx:U13>
         <PDBx:U22>0.2638</PDBx:U22>
         <PDBx:U23>-0.0341</PDBx:U23>
         <PDBx:U33>0.2173</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1123">
         <PDBx:U11>0.2348</PDBx:U11>
         <PDBx:U12>-0.0423</PDBx:U12>
         <PDBx:U13>0.0321</PDBx:U13>
         <PDBx:U22>0.2352</PDBx:U22>
         <PDBx:U23>-0.0312</PDBx:U23>
         <PDBx:U33>0.2333</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1124">
         <PDBx:U11>0.2562</PDBx:U11>
         <PDBx:U12>-0.0145</PDBx:U12>
         <PDBx:U13>-0.0483</PDBx:U13>
         <PDBx:U22>0.2802</PDBx:U22>
         <PDBx:U23>-0.0291</PDBx:U23>
         <PDBx:U33>0.2313</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1125">
         <PDBx:U11>0.2131</PDBx:U11>
         <PDBx:U12>-0.0081</PDBx:U12>
         <PDBx:U13>-0.0091</PDBx:U13>
         <PDBx:U22>0.1827</PDBx:U22>
         <PDBx:U23>-0.0227</PDBx:U23>
         <PDBx:U33>0.1658</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1126">
         <PDBx:U11>0.2204</PDBx:U11>
         <PDBx:U12>-0.0333</PDBx:U12>
         <PDBx:U13>-0.0070</PDBx:U13>
         <PDBx:U22>0.1879</PDBx:U22>
         <PDBx:U23>-0.0143</PDBx:U23>
         <PDBx:U33>0.1868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1127">
         <PDBx:U11>0.2047</PDBx:U11>
         <PDBx:U12>0.0125</PDBx:U12>
         <PDBx:U13>-0.0042</PDBx:U13>
         <PDBx:U22>0.1845</PDBx:U22>
         <PDBx:U23>0.0089</PDBx:U23>
         <PDBx:U33>0.2042</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1128">
         <PDBx:U11>0.2157</PDBx:U11>
         <PDBx:U12>0.0274</PDBx:U12>
         <PDBx:U13>0.0157</PDBx:U13>
         <PDBx:U22>0.2069</PDBx:U22>
         <PDBx:U23>0.0151</PDBx:U23>
         <PDBx:U33>0.1814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1129">
         <PDBx:U11>0.2318</PDBx:U11>
         <PDBx:U12>-0.0111</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.1685</PDBx:U22>
         <PDBx:U23>-0.0133</PDBx:U23>
         <PDBx:U33>0.1802</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1130">
         <PDBx:U11>0.1972</PDBx:U11>
         <PDBx:U12>-0.0021</PDBx:U12>
         <PDBx:U13>-0.0040</PDBx:U13>
         <PDBx:U22>0.2033</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1813</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1131">
         <PDBx:U11>0.2468</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>0.0167</PDBx:U13>
         <PDBx:U22>0.1814</PDBx:U22>
         <PDBx:U23>0.0256</PDBx:U23>
         <PDBx:U33>0.2090</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1132">
         <PDBx:U11>0.2275</PDBx:U11>
         <PDBx:U12>-0.0085</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.1647</PDBx:U22>
         <PDBx:U23>0.0082</PDBx:U23>
         <PDBx:U33>0.1681</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1133">
         <PDBx:U11>0.2204</PDBx:U11>
         <PDBx:U12>-0.0296</PDBx:U12>
         <PDBx:U13>-0.0091</PDBx:U13>
         <PDBx:U22>0.1761</PDBx:U22>
         <PDBx:U23>0.0266</PDBx:U23>
         <PDBx:U33>0.1766</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1134">
         <PDBx:U11>0.2121</PDBx:U11>
         <PDBx:U12>-0.0171</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.1759</PDBx:U22>
         <PDBx:U23>-0.0016</PDBx:U23>
         <PDBx:U33>0.1895</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1135">
         <PDBx:U11>0.2159</PDBx:U11>
         <PDBx:U12>0.0040</PDBx:U12>
         <PDBx:U13>-0.0081</PDBx:U13>
         <PDBx:U22>0.1921</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.2076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1136">
         <PDBx:U11>0.2399</PDBx:U11>
         <PDBx:U12>-0.0304</PDBx:U12>
         <PDBx:U13>-0.0157</PDBx:U13>
         <PDBx:U22>0.1679</PDBx:U22>
         <PDBx:U23>0.0077</PDBx:U23>
         <PDBx:U33>0.1916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1137">
         <PDBx:U11>0.2145</PDBx:U11>
         <PDBx:U12>-0.0418</PDBx:U12>
         <PDBx:U13>-0.0022</PDBx:U13>
         <PDBx:U22>0.1930</PDBx:U22>
         <PDBx:U23>0.0106</PDBx:U23>
         <PDBx:U33>0.2041</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1138">
         <PDBx:U11>0.2439</PDBx:U11>
         <PDBx:U12>-0.0293</PDBx:U12>
         <PDBx:U13>-0.0171</PDBx:U13>
         <PDBx:U22>0.1816</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.2443</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1139">
         <PDBx:U11>0.2684</PDBx:U11>
         <PDBx:U12>-0.0409</PDBx:U12>
         <PDBx:U13>-0.0049</PDBx:U13>
         <PDBx:U22>0.2274</PDBx:U22>
         <PDBx:U23>-0.0223</PDBx:U23>
         <PDBx:U33>0.2403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1140">
         <PDBx:U11>0.2323</PDBx:U11>
         <PDBx:U12>-0.0448</PDBx:U12>
         <PDBx:U13>0.0281</PDBx:U13>
         <PDBx:U22>0.2518</PDBx:U22>
         <PDBx:U23>0.0123</PDBx:U23>
         <PDBx:U33>0.3022</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1141">
         <PDBx:U11>0.2057</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.1699</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.1826</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1142">
         <PDBx:U11>0.2006</PDBx:U11>
         <PDBx:U12>0.0074</PDBx:U12>
         <PDBx:U13>-0.0212</PDBx:U13>
         <PDBx:U22>0.1661</PDBx:U22>
         <PDBx:U23>-0.0085</PDBx:U23>
         <PDBx:U33>0.1749</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1143">
         <PDBx:U11>0.2053</PDBx:U11>
         <PDBx:U12>0.0032</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.1724</PDBx:U22>
         <PDBx:U23>0.0044</PDBx:U23>
         <PDBx:U33>0.2030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1144">
         <PDBx:U11>0.2196</PDBx:U11>
         <PDBx:U12>-0.0050</PDBx:U12>
         <PDBx:U13>0.0166</PDBx:U13>
         <PDBx:U22>0.1900</PDBx:U22>
         <PDBx:U23>0.0157</PDBx:U23>
         <PDBx:U33>0.2000</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1145">
         <PDBx:U11>0.2059</PDBx:U11>
         <PDBx:U12>0.0057</PDBx:U12>
         <PDBx:U13>-0.0171</PDBx:U13>
         <PDBx:U22>0.1872</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.2063</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1146">
         <PDBx:U11>0.2781</PDBx:U11>
         <PDBx:U12>-0.0217</PDBx:U12>
         <PDBx:U13>-0.0412</PDBx:U13>
         <PDBx:U22>0.2256</PDBx:U22>
         <PDBx:U23>-0.0163</PDBx:U23>
         <PDBx:U33>0.1982</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1147">
         <PDBx:U11>0.2232</PDBx:U11>
         <PDBx:U12>-0.0002</PDBx:U12>
         <PDBx:U13>-0.0062</PDBx:U13>
         <PDBx:U22>0.1713</PDBx:U22>
         <PDBx:U23>0.0113</PDBx:U23>
         <PDBx:U33>0.2249</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1148">
         <PDBx:U11>0.2303</PDBx:U11>
         <PDBx:U12>0.0074</PDBx:U12>
         <PDBx:U13>-0.0272</PDBx:U13>
         <PDBx:U22>0.1616</PDBx:U22>
         <PDBx:U23>0.0343</PDBx:U23>
         <PDBx:U33>0.1900</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1149">
         <PDBx:U11>0.2238</PDBx:U11>
         <PDBx:U12>0.0151</PDBx:U12>
         <PDBx:U13>-0.0075</PDBx:U13>
         <PDBx:U22>0.1535</PDBx:U22>
         <PDBx:U23>0.0206</PDBx:U23>
         <PDBx:U33>0.1872</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1150">
         <PDBx:U11>0.2101</PDBx:U11>
         <PDBx:U12>-0.0261</PDBx:U12>
         <PDBx:U13>-0.0312</PDBx:U13>
         <PDBx:U22>0.1746</PDBx:U22>
         <PDBx:U23>0.0255</PDBx:U23>
         <PDBx:U33>0.1989</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1151">
         <PDBx:U11>0.2493</PDBx:U11>
         <PDBx:U12>-0.0125</PDBx:U12>
         <PDBx:U13>-0.0077</PDBx:U13>
         <PDBx:U22>0.1678</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.2207</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1152">
         <PDBx:U11>0.3163</PDBx:U11>
         <PDBx:U12>0.0815</PDBx:U12>
         <PDBx:U13>0.0268</PDBx:U13>
         <PDBx:U22>0.1626</PDBx:U22>
         <PDBx:U23>-0.0291</PDBx:U23>
         <PDBx:U33>0.2484</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1153">
         <PDBx:U11>0.3525</PDBx:U11>
         <PDBx:U12>0.0377</PDBx:U12>
         <PDBx:U13>-0.0070</PDBx:U13>
         <PDBx:U22>0.2656</PDBx:U22>
         <PDBx:U23>0.0318</PDBx:U23>
         <PDBx:U33>0.2741</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1154">
         <PDBx:U11>0.2399</PDBx:U11>
         <PDBx:U12>0.0046</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.1822</PDBx:U22>
         <PDBx:U23>0.0110</PDBx:U23>
         <PDBx:U33>0.1780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1155">
         <PDBx:U11>0.2379</PDBx:U11>
         <PDBx:U12>0.0196</PDBx:U12>
         <PDBx:U13>-0.0085</PDBx:U13>
         <PDBx:U22>0.2230</PDBx:U22>
         <PDBx:U23>-0.0317</PDBx:U23>
         <PDBx:U33>0.1867</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1156">
         <PDBx:U11>0.2487</PDBx:U11>
         <PDBx:U12>0.0138</PDBx:U12>
         <PDBx:U13>-0.0126</PDBx:U13>
         <PDBx:U22>0.1644</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.2168</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1157">
         <PDBx:U11>0.2387</PDBx:U11>
         <PDBx:U12>0.0269</PDBx:U12>
         <PDBx:U13>-0.0257</PDBx:U13>
         <PDBx:U22>0.2249</PDBx:U22>
         <PDBx:U23>-0.0162</PDBx:U23>
         <PDBx:U33>0.2324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1158">
         <PDBx:U11>0.2652</PDBx:U11>
         <PDBx:U12>0.0344</PDBx:U12>
         <PDBx:U13>-0.0241</PDBx:U13>
         <PDBx:U22>0.2328</PDBx:U22>
         <PDBx:U23>-0.0194</PDBx:U23>
         <PDBx:U33>0.2603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1159">
         <PDBx:U11>0.2852</PDBx:U11>
         <PDBx:U12>-0.0178</PDBx:U12>
         <PDBx:U13>0.0173</PDBx:U13>
         <PDBx:U22>0.2217</PDBx:U22>
         <PDBx:U23>-0.0247</PDBx:U23>
         <PDBx:U33>0.2430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1160">
         <PDBx:U11>0.3502</PDBx:U11>
         <PDBx:U12>-0.0068</PDBx:U12>
         <PDBx:U13>0.0646</PDBx:U13>
         <PDBx:U22>0.2592</PDBx:U22>
         <PDBx:U23>-0.0482</PDBx:U23>
         <PDBx:U33>0.2961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1161">
         <PDBx:U11>0.3289</PDBx:U11>
         <PDBx:U12>0.0372</PDBx:U12>
         <PDBx:U13>0.0137</PDBx:U13>
         <PDBx:U22>0.2092</PDBx:U22>
         <PDBx:U23>0.0105</PDBx:U23>
         <PDBx:U33>0.2573</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>163</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1162">
         <PDBx:U11>0.2447</PDBx:U11>
         <PDBx:U12>0.0258</PDBx:U12>
         <PDBx:U13>0.0218</PDBx:U13>
         <PDBx:U22>0.2188</PDBx:U22>
         <PDBx:U23>0.0164</PDBx:U23>
         <PDBx:U33>0.2060</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1163">
         <PDBx:U11>0.2312</PDBx:U11>
         <PDBx:U12>0.0298</PDBx:U12>
         <PDBx:U13>0.0119</PDBx:U13>
         <PDBx:U22>0.2135</PDBx:U22>
         <PDBx:U23>0.0282</PDBx:U23>
         <PDBx:U33>0.2033</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1164">
         <PDBx:U11>0.2884</PDBx:U11>
         <PDBx:U12>-0.0141</PDBx:U12>
         <PDBx:U13>0.0116</PDBx:U13>
         <PDBx:U22>0.2076</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1884</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1165">
         <PDBx:U11>0.2326</PDBx:U11>
         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>0.0125</PDBx:U13>
         <PDBx:U22>0.2085</PDBx:U22>
         <PDBx:U23>-0.0132</PDBx:U23>
         <PDBx:U33>0.2041</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1166">
         <PDBx:U11>0.2296</PDBx:U11>
         <PDBx:U12>0.0134</PDBx:U12>
         <PDBx:U13>-0.0372</PDBx:U13>
         <PDBx:U22>0.1672</PDBx:U22>
         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.2508</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1167">
         <PDBx:U11>0.2136</PDBx:U11>
         <PDBx:U12>0.0168</PDBx:U12>
         <PDBx:U13>-0.0214</PDBx:U13>
         <PDBx:U22>0.1939</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.2204</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1168">
         <PDBx:U11>0.2363</PDBx:U11>
         <PDBx:U12>0.0058</PDBx:U12>
         <PDBx:U13>-0.0520</PDBx:U13>
         <PDBx:U22>0.2320</PDBx:U22>
         <PDBx:U23>0.0128</PDBx:U23>
         <PDBx:U33>0.2157</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1169">
         <PDBx:U11>0.2449</PDBx:U11>
         <PDBx:U12>-0.0014</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.2567</PDBx:U22>
         <PDBx:U23>0.0180</PDBx:U23>
         <PDBx:U33>0.2244</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1170">
         <PDBx:U11>0.2703</PDBx:U11>
         <PDBx:U12>0.0221</PDBx:U12>
         <PDBx:U13>-0.0353</PDBx:U13>
         <PDBx:U22>0.2335</PDBx:U22>
         <PDBx:U23>0.0210</PDBx:U23>
         <PDBx:U33>0.2113</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1171">
         <PDBx:U11>0.2376</PDBx:U11>
         <PDBx:U12>-0.0153</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.2740</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.2631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1172">
         <PDBx:U11>0.2716</PDBx:U11>
         <PDBx:U12>-0.0106</PDBx:U12>
         <PDBx:U13>-0.0234</PDBx:U13>
         <PDBx:U22>0.2596</PDBx:U22>
         <PDBx:U23>0.0113</PDBx:U23>
         <PDBx:U33>0.2668</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>164</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1173">
         <PDBx:U11>0.1924</PDBx:U11>
         <PDBx:U12>-0.0111</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.1953</PDBx:U22>
         <PDBx:U23>0.0210</PDBx:U23>
         <PDBx:U33>0.1709</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>165</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1174">
         <PDBx:U11>0.2634</PDBx:U11>
         <PDBx:U12>0.0355</PDBx:U12>
         <PDBx:U13>-0.0087</PDBx:U13>
         <PDBx:U22>0.2444</PDBx:U22>
         <PDBx:U23>0.0242</PDBx:U23>
         <PDBx:U33>0.1779</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>165</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1175">
         <PDBx:U11>0.2037</PDBx:U11>
         <PDBx:U12>-0.0246</PDBx:U12>
         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.2089</PDBx:U22>
         <PDBx:U23>-0.0110</PDBx:U23>
         <PDBx:U33>0.2043</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>165</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1176">
         <PDBx:U11>0.2687</PDBx:U11>
         <PDBx:U12>0.0164</PDBx:U12>
         <PDBx:U13>0.0120</PDBx:U13>
         <PDBx:U22>0.2400</PDBx:U22>
         <PDBx:U23>0.0183</PDBx:U23>
         <PDBx:U33>0.2050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>165</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1177">
         <PDBx:U11>0.1999</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>0.0094</PDBx:U13>
         <PDBx:U22>0.1887</PDBx:U22>
         <PDBx:U23>0.0046</PDBx:U23>
         <PDBx:U33>0.1994</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1178">
         <PDBx:U11>0.2045</PDBx:U11>
         <PDBx:U12>0.0070</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.1797</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.1976</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1179">
         <PDBx:U11>0.1949</PDBx:U11>
         <PDBx:U12>0.0279</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.1743</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.2007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1180">
         <PDBx:U11>0.2056</PDBx:U11>
         <PDBx:U12>0.0235</PDBx:U12>
         <PDBx:U13>-0.0181</PDBx:U13>
         <PDBx:U22>0.1869</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1833</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1181">
         <PDBx:U11>0.2449</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>-0.0117</PDBx:U13>
         <PDBx:U22>0.1808</PDBx:U22>
         <PDBx:U23>-0.0289</PDBx:U23>
         <PDBx:U33>0.2077</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1182">
         <PDBx:U11>0.2358</PDBx:U11>
         <PDBx:U12>-0.0368</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.2205</PDBx:U22>
         <PDBx:U23>-0.0151</PDBx:U23>
         <PDBx:U33>0.2291</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1183">
         <PDBx:U11>0.3380</PDBx:U11>
         <PDBx:U12>0.0079</PDBx:U12>
         <PDBx:U13>-0.0324</PDBx:U13>
         <PDBx:U22>0.2266</PDBx:U22>
         <PDBx:U23>-0.0521</PDBx:U23>
         <PDBx:U33>0.2459</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1184">
         <PDBx:U11>0.3509</PDBx:U11>
         <PDBx:U12>-0.0416</PDBx:U12>
         <PDBx:U13>0.0227</PDBx:U13>
         <PDBx:U22>0.2309</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.2782</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>166</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1185">
         <PDBx:U11>0.2001</PDBx:U11>
         <PDBx:U12>-0.0203</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.1923</PDBx:U22>
         <PDBx:U23>0.0084</PDBx:U23>
         <PDBx:U33>0.1773</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1186">
         <PDBx:U11>0.2249</PDBx:U11>
         <PDBx:U12>-0.0095</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.1547</PDBx:U22>
         <PDBx:U23>0.0088</PDBx:U23>
         <PDBx:U33>0.1791</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1187">
         <PDBx:U11>0.2144</PDBx:U11>
         <PDBx:U12>-0.0094</PDBx:U12>
         <PDBx:U13>-0.0082</PDBx:U13>
         <PDBx:U22>0.2143</PDBx:U22>
         <PDBx:U23>0.0284</PDBx:U23>
         <PDBx:U33>0.1925</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1188">
         <PDBx:U11>0.2216</PDBx:U11>
         <PDBx:U12>0.0081</PDBx:U12>
         <PDBx:U13>-0.0156</PDBx:U13>
         <PDBx:U22>0.2129</PDBx:U22>
         <PDBx:U23>0.0294</PDBx:U23>
         <PDBx:U33>0.2032</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1189">
         <PDBx:U11>0.2478</PDBx:U11>
         <PDBx:U12>0.0249</PDBx:U12>
         <PDBx:U13>0.0363</PDBx:U13>
         <PDBx:U22>0.1586</PDBx:U22>
         <PDBx:U23>0.0272</PDBx:U23>
         <PDBx:U33>0.2084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1190">
         <PDBx:U11>0.2282</PDBx:U11>
         <PDBx:U12>-0.0161</PDBx:U12>
         <PDBx:U13>0.0113</PDBx:U13>
         <PDBx:U22>0.1808</PDBx:U22>
         <PDBx:U23>0.0028</PDBx:U23>
         <PDBx:U33>0.2271</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1191">
         <PDBx:U11>0.2469</PDBx:U11>
         <PDBx:U12>-0.0294</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.1876</PDBx:U22>
         <PDBx:U23>-0.0041</PDBx:U23>
         <PDBx:U33>0.1484</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1192">
         <PDBx:U11>0.2183</PDBx:U11>
         <PDBx:U12>0.0064</PDBx:U12>
         <PDBx:U13>0.0113</PDBx:U13>
         <PDBx:U22>0.2126</PDBx:U22>
         <PDBx:U23>0.0171</PDBx:U23>
         <PDBx:U33>0.1705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1193">
         <PDBx:U11>0.2608</PDBx:U11>
         <PDBx:U12>0.0112</PDBx:U12>
         <PDBx:U13>-0.0296</PDBx:U13>
         <PDBx:U22>0.2020</PDBx:U22>
         <PDBx:U23>-0.0131</PDBx:U23>
         <PDBx:U33>0.1951</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1194">
         <PDBx:U11>0.2905</PDBx:U11>
         <PDBx:U12>0.0420</PDBx:U12>
         <PDBx:U13>-0.0167</PDBx:U13>
         <PDBx:U22>0.2013</PDBx:U22>
         <PDBx:U23>0.0124</PDBx:U23>
         <PDBx:U33>0.1862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1195">
         <PDBx:U11>0.2186</PDBx:U11>
         <PDBx:U12>0.0439</PDBx:U12>
         <PDBx:U13>0.0398</PDBx:U13>
         <PDBx:U22>0.2176</PDBx:U22>
         <PDBx:U23>0.0064</PDBx:U23>
         <PDBx:U33>0.2154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1196">
         <PDBx:U11>0.2655</PDBx:U11>
         <PDBx:U12>0.0400</PDBx:U12>
         <PDBx:U13>0.0100</PDBx:U13>
         <PDBx:U22>0.1984</PDBx:U22>
         <PDBx:U23>0.0309</PDBx:U23>
         <PDBx:U33>0.1993</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1197">
         <PDBx:U11>0.2764</PDBx:U11>
         <PDBx:U12>0.0119</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.2763</PDBx:U22>
         <PDBx:U23>0.0097</PDBx:U23>
         <PDBx:U33>0.2322</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1198">
         <PDBx:U11>0.2529</PDBx:U11>
         <PDBx:U12>0.0343</PDBx:U12>
         <PDBx:U13>-0.0187</PDBx:U13>
         <PDBx:U22>0.2932</PDBx:U22>
         <PDBx:U23>0.0378</PDBx:U23>
         <PDBx:U33>0.2359</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1199">
         <PDBx:U11>0.3192</PDBx:U11>
         <PDBx:U12>-0.0279</PDBx:U12>
         <PDBx:U13>0.0429</PDBx:U13>
         <PDBx:U22>0.2783</PDBx:U22>
         <PDBx:U23>-0.0295</PDBx:U23>
         <PDBx:U33>0.2664</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1200">
         <PDBx:U11>0.2953</PDBx:U11>
         <PDBx:U12>-0.0168</PDBx:U12>
         <PDBx:U13>0.0676</PDBx:U13>
         <PDBx:U22>0.3328</PDBx:U22>
         <PDBx:U23>0.0088</PDBx:U23>
         <PDBx:U33>0.2823</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1201">
         <PDBx:U11>0.3176</PDBx:U11>
         <PDBx:U12>0.0380</PDBx:U12>
         <PDBx:U13>-0.0199</PDBx:U13>
         <PDBx:U22>0.3267</PDBx:U22>
         <PDBx:U23>-0.0257</PDBx:U23>
         <PDBx:U33>0.2521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1202">
         <PDBx:U11>0.2221</PDBx:U11>
         <PDBx:U12>0.0322</PDBx:U12>
         <PDBx:U13>0.0034</PDBx:U13>
         <PDBx:U22>0.1748</PDBx:U22>
         <PDBx:U23>0.0058</PDBx:U23>
         <PDBx:U33>0.1922</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1203">
         <PDBx:U11>0.2464</PDBx:U11>
         <PDBx:U12>0.0209</PDBx:U12>
         <PDBx:U13>-0.0078</PDBx:U13>
         <PDBx:U22>0.1802</PDBx:U22>
         <PDBx:U23>0.0055</PDBx:U23>
         <PDBx:U33>0.2414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1204">
         <PDBx:U11>0.2309</PDBx:U11>
         <PDBx:U12>-0.0146</PDBx:U12>
         <PDBx:U13>-0.0042</PDBx:U13>
         <PDBx:U22>0.2011</PDBx:U22>
         <PDBx:U23>0.0102</PDBx:U23>
         <PDBx:U33>0.2141</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1205">
         <PDBx:U11>0.2288</PDBx:U11>
         <PDBx:U12>0.0100</PDBx:U12>
         <PDBx:U13>0.0141</PDBx:U13>
         <PDBx:U22>0.2168</PDBx:U22>
         <PDBx:U23>0.0062</PDBx:U23>
         <PDBx:U33>0.2251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1206">
         <PDBx:U11>0.2538</PDBx:U11>
         <PDBx:U12>-0.0152</PDBx:U12>
         <PDBx:U13>0.0291</PDBx:U13>
         <PDBx:U22>0.1978</PDBx:U22>
         <PDBx:U23>-0.0311</PDBx:U23>
         <PDBx:U33>0.2569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1207">
         <PDBx:U11>0.2349</PDBx:U11>
         <PDBx:U12>0.0225</PDBx:U12>
         <PDBx:U13>-0.0121</PDBx:U13>
         <PDBx:U22>0.1736</PDBx:U22>
         <PDBx:U23>-0.0149</PDBx:U23>
         <PDBx:U33>0.2111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1208">
         <PDBx:U11>0.2563</PDBx:U11>
         <PDBx:U12>0.0333</PDBx:U12>
         <PDBx:U13>0.0288</PDBx:U13>
         <PDBx:U22>0.2444</PDBx:U22>
         <PDBx:U23>0.0508</PDBx:U23>
         <PDBx:U33>0.2329</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1209">
         <PDBx:U11>0.2303</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>-0.0172</PDBx:U13>
         <PDBx:U22>0.2018</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.2358</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1210">
         <PDBx:U11>0.2346</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0132</PDBx:U13>
         <PDBx:U22>0.2842</PDBx:U22>
         <PDBx:U23>0.0247</PDBx:U23>
         <PDBx:U33>0.2391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1211">
         <PDBx:U11>0.2554</PDBx:U11>
         <PDBx:U12>0.0256</PDBx:U12>
         <PDBx:U13>0.0274</PDBx:U13>
         <PDBx:U22>0.2532</PDBx:U22>
         <PDBx:U23>0.0300</PDBx:U23>
         <PDBx:U33>0.2464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1212">
         <PDBx:U11>0.2379</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>0.0203</PDBx:U13>
         <PDBx:U22>0.3119</PDBx:U22>
         <PDBx:U23>0.0485</PDBx:U23>
         <PDBx:U33>0.2606</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1213">
         <PDBx:U11>0.3059</PDBx:U11>
         <PDBx:U12>0.0615</PDBx:U12>
         <PDBx:U13>0.0148</PDBx:U13>
         <PDBx:U22>0.3592</PDBx:U22>
         <PDBx:U23>0.0922</PDBx:U23>
         <PDBx:U33>0.3212</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1214">
         <PDBx:U11>0.2436</PDBx:U11>
         <PDBx:U12>0.0009</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.1887</PDBx:U22>
         <PDBx:U23>0.0018</PDBx:U23>
         <PDBx:U33>0.1955</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1215">
         <PDBx:U11>0.2274</PDBx:U11>
         <PDBx:U12>-0.0096</PDBx:U12>
         <PDBx:U13>-0.0124</PDBx:U13>
         <PDBx:U22>0.2291</PDBx:U22>
         <PDBx:U23>0.0548</PDBx:U23>
         <PDBx:U33>0.1920</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1216">
         <PDBx:U11>0.2292</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.1932</PDBx:U22>
         <PDBx:U23>0.0247</PDBx:U23>
         <PDBx:U33>0.1902</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1217">
         <PDBx:U11>0.2452</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.2065</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.2218</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1218">
         <PDBx:U11>0.2386</PDBx:U11>
         <PDBx:U12>-0.0247</PDBx:U12>
         <PDBx:U13>-0.0223</PDBx:U13>
         <PDBx:U22>0.1976</PDBx:U22>
         <PDBx:U23>0.0376</PDBx:U23>
         <PDBx:U33>0.2053</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1219">
         <PDBx:U11>0.2262</PDBx:U11>
         <PDBx:U12>0.0032</PDBx:U12>
         <PDBx:U13>-0.0182</PDBx:U13>
         <PDBx:U22>0.2452</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.2467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1220">
         <PDBx:U11>0.2468</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>-0.0426</PDBx:U13>
         <PDBx:U22>0.1951</PDBx:U22>
         <PDBx:U23>0.0129</PDBx:U23>
         <PDBx:U33>0.2231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1221">
         <PDBx:U11>0.2153</PDBx:U11>
         <PDBx:U12>0.0159</PDBx:U12>
         <PDBx:U13>-0.0289</PDBx:U13>
         <PDBx:U22>0.2334</PDBx:U22>
         <PDBx:U23>0.0175</PDBx:U23>
         <PDBx:U33>0.2127</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1222">
         <PDBx:U11>0.2411</PDBx:U11>
         <PDBx:U12>0.0065</PDBx:U12>
         <PDBx:U13>-0.0452</PDBx:U13>
         <PDBx:U22>0.2234</PDBx:U22>
         <PDBx:U23>0.0040</PDBx:U23>
         <PDBx:U33>0.2306</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1223">
         <PDBx:U11>0.2711</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.2857</PDBx:U22>
         <PDBx:U23>0.0346</PDBx:U23>
         <PDBx:U33>0.3794</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1224">
         <PDBx:U11>0.3275</PDBx:U11>
         <PDBx:U12>0.0224</PDBx:U12>
         <PDBx:U13>0.0424</PDBx:U13>
         <PDBx:U22>0.3282</PDBx:U22>
         <PDBx:U23>-0.0159</PDBx:U23>
         <PDBx:U33>0.4341</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1225">
         <PDBx:U11>0.2502</PDBx:U11>
         <PDBx:U12>0.0069</PDBx:U12>
         <PDBx:U13>-0.0231</PDBx:U13>
         <PDBx:U22>0.2275</PDBx:U22>
         <PDBx:U23>0.0268</PDBx:U23>
         <PDBx:U33>0.2364</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1226">
         <PDBx:U11>0.2796</PDBx:U11>
         <PDBx:U12>0.0036</PDBx:U12>
         <PDBx:U13>0.0099</PDBx:U13>
         <PDBx:U22>0.1953</PDBx:U22>
         <PDBx:U23>0.0296</PDBx:U23>
         <PDBx:U33>0.2660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1227">
         <PDBx:U11>0.3842</PDBx:U11>
         <PDBx:U12>0.0173</PDBx:U12>
         <PDBx:U13>-0.0545</PDBx:U13>
         <PDBx:U22>0.2236</PDBx:U22>
         <PDBx:U23>0.0770</PDBx:U23>
         <PDBx:U33>0.3075</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1228">
         <PDBx:U11>0.3260</PDBx:U11>
         <PDBx:U12>0.0230</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.2701</PDBx:U22>
         <PDBx:U23>0.0113</PDBx:U23>
         <PDBx:U33>0.2377</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1229">
         <PDBx:U11>0.2403</PDBx:U11>
         <PDBx:U12>0.0098</PDBx:U12>
         <PDBx:U13>-0.0152</PDBx:U13>
         <PDBx:U22>0.2595</PDBx:U22>
         <PDBx:U23>0.0482</PDBx:U23>
         <PDBx:U33>0.2842</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1230">
         <PDBx:U11>0.2428</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>-0.0170</PDBx:U13>
         <PDBx:U22>0.2833</PDBx:U22>
         <PDBx:U23>0.0135</PDBx:U23>
         <PDBx:U33>0.2442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1231">
         <PDBx:U11>0.2655</PDBx:U11>
         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>-0.0506</PDBx:U13>
         <PDBx:U22>0.2788</PDBx:U22>
         <PDBx:U23>-0.0236</PDBx:U23>
         <PDBx:U33>0.2426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1232">
         <PDBx:U11>0.2381</PDBx:U11>
         <PDBx:U12>-0.0209</PDBx:U12>
         <PDBx:U13>0.0007</PDBx:U13>
         <PDBx:U22>0.2607</PDBx:U22>
         <PDBx:U23>0.0215</PDBx:U23>
         <PDBx:U33>0.2660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1233">
         <PDBx:U11>0.2573</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>0.0094</PDBx:U13>
         <PDBx:U22>0.2979</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.2212</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1234">
         <PDBx:U11>0.2932</PDBx:U11>
         <PDBx:U12>-0.0307</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.3028</PDBx:U22>
         <PDBx:U23>0.0121</PDBx:U23>
         <PDBx:U33>0.2837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1235">
         <PDBx:U11>0.3043</PDBx:U11>
         <PDBx:U12>-0.0663</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.3142</PDBx:U22>
         <PDBx:U23>-0.0123</PDBx:U23>
         <PDBx:U33>0.2650</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1236">
         <PDBx:U11>0.3494</PDBx:U11>
         <PDBx:U12>-0.0293</PDBx:U12>
         <PDBx:U13>0.0094</PDBx:U13>
         <PDBx:U22>0.3246</PDBx:U22>
         <PDBx:U23>0.0330</PDBx:U23>
         <PDBx:U33>0.2879</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1237">
         <PDBx:U11>0.2717</PDBx:U11>
         <PDBx:U12>-0.0384</PDBx:U12>
         <PDBx:U13>-0.0321</PDBx:U13>
         <PDBx:U22>0.2397</PDBx:U22>
         <PDBx:U23>0.0037</PDBx:U23>
         <PDBx:U33>0.2143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1238">
         <PDBx:U11>0.3928</PDBx:U11>
         <PDBx:U12>0.0562</PDBx:U12>
         <PDBx:U13>-0.0381</PDBx:U13>
         <PDBx:U22>0.2388</PDBx:U22>
         <PDBx:U23>0.0133</PDBx:U23>
         <PDBx:U33>0.2455</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1239">
         <PDBx:U11>0.2949</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>-0.0079</PDBx:U13>
         <PDBx:U22>0.2830</PDBx:U22>
         <PDBx:U23>0.0262</PDBx:U23>
         <PDBx:U33>0.2604</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1240">
         <PDBx:U11>0.3291</PDBx:U11>
         <PDBx:U12>-0.0395</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.2922</PDBx:U22>
         <PDBx:U23>0.0426</PDBx:U23>
         <PDBx:U33>0.2966</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1241">
         <PDBx:U11>0.3213</PDBx:U11>
         <PDBx:U12>-0.0571</PDBx:U12>
         <PDBx:U13>-0.0521</PDBx:U13>
         <PDBx:U22>0.3017</PDBx:U22>
         <PDBx:U23>0.0152</PDBx:U23>
         <PDBx:U33>0.3051</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1242">
         <PDBx:U11>0.3832</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>-0.0091</PDBx:U13>
         <PDBx:U22>0.4401</PDBx:U22>
         <PDBx:U23>0.0461</PDBx:U23>
         <PDBx:U33>0.3628</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1243">
         <PDBx:U11>0.4925</PDBx:U11>
         <PDBx:U12>0.0125</PDBx:U12>
         <PDBx:U13>0.0315</PDBx:U13>
         <PDBx:U22>0.4083</PDBx:U22>
         <PDBx:U23>0.0932</PDBx:U23>
         <PDBx:U33>0.3522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1244">
         <PDBx:U11>0.5519</PDBx:U11>
         <PDBx:U12>0.1741</PDBx:U12>
         <PDBx:U13>-0.0245</PDBx:U13>
         <PDBx:U22>0.4817</PDBx:U22>
         <PDBx:U23>0.0434</PDBx:U23>
         <PDBx:U33>0.4407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1245">
         <PDBx:U11>0.2073</PDBx:U11>
         <PDBx:U12>0.0084</PDBx:U12>
         <PDBx:U13>-0.0291</PDBx:U13>
         <PDBx:U22>0.2630</PDBx:U22>
         <PDBx:U23>0.0584</PDBx:U23>
         <PDBx:U33>0.2651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1246">
         <PDBx:U11>0.2298</PDBx:U11>
         <PDBx:U12>0.0162</PDBx:U12>
         <PDBx:U13>-0.0254</PDBx:U13>
         <PDBx:U22>0.3038</PDBx:U22>
         <PDBx:U23>0.0474</PDBx:U23>
         <PDBx:U33>0.2199</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1247">
         <PDBx:U11>0.2486</PDBx:U11>
         <PDBx:U12>0.0108</PDBx:U12>
         <PDBx:U13>-0.0236</PDBx:U13>
         <PDBx:U22>0.2722</PDBx:U22>
         <PDBx:U23>0.0416</PDBx:U23>
         <PDBx:U33>0.2531</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1248">
         <PDBx:U11>0.2578</PDBx:U11>
         <PDBx:U12>-0.0254</PDBx:U12>
         <PDBx:U13>-0.0191</PDBx:U13>
         <PDBx:U22>0.2629</PDBx:U22>
         <PDBx:U23>0.0535</PDBx:U23>
         <PDBx:U33>0.2766</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1249">
         <PDBx:U11>0.2264</PDBx:U11>
         <PDBx:U12>-0.0293</PDBx:U12>
         <PDBx:U13>-0.0177</PDBx:U13>
         <PDBx:U22>0.3617</PDBx:U22>
         <PDBx:U23>0.0237</PDBx:U23>
         <PDBx:U33>0.2698</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1250">
         <PDBx:U11>0.2774</PDBx:U11>
         <PDBx:U12>-0.0194</PDBx:U12>
         <PDBx:U13>-0.0656</PDBx:U13>
         <PDBx:U22>0.4228</PDBx:U22>
         <PDBx:U23>0.0686</PDBx:U23>
         <PDBx:U33>0.3763</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1251">
         <PDBx:U11>0.4227</PDBx:U11>
         <PDBx:U12>-0.0756</PDBx:U12>
         <PDBx:U13>-0.1156</PDBx:U13>
         <PDBx:U22>0.4909</PDBx:U22>
         <PDBx:U23>0.0816</PDBx:U23>
         <PDBx:U33>0.4175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1252">
         <PDBx:U11>0.3090</PDBx:U11>
         <PDBx:U12>-0.0288</PDBx:U12>
         <PDBx:U13>-0.0596</PDBx:U13>
         <PDBx:U22>0.5181</PDBx:U22>
         <PDBx:U23>0.1152</PDBx:U23>
         <PDBx:U33>0.4908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1253">
         <PDBx:U11>0.4183</PDBx:U11>
         <PDBx:U12>-0.1092</PDBx:U12>
         <PDBx:U13>-0.1393</PDBx:U13>
         <PDBx:U22>0.4994</PDBx:U22>
         <PDBx:U23>0.1089</PDBx:U23>
         <PDBx:U33>0.4805</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1254">
         <PDBx:U11>0.2357</PDBx:U11>
         <PDBx:U12>-0.0313</PDBx:U12>
         <PDBx:U13>-0.0220</PDBx:U13>
         <PDBx:U22>0.2896</PDBx:U22>
         <PDBx:U23>0.0134</PDBx:U23>
         <PDBx:U33>0.1957</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1255">
         <PDBx:U11>0.2461</PDBx:U11>
         <PDBx:U12>0.0058</PDBx:U12>
         <PDBx:U13>-0.0075</PDBx:U13>
         <PDBx:U22>0.2540</PDBx:U22>
         <PDBx:U23>0.0128</PDBx:U23>
         <PDBx:U33>0.2107</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1256">
         <PDBx:U11>0.2127</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>-0.0156</PDBx:U13>
         <PDBx:U22>0.2478</PDBx:U22>
         <PDBx:U23>0.0165</PDBx:U23>
         <PDBx:U33>0.2512</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1257">
         <PDBx:U11>0.2419</PDBx:U11>
         <PDBx:U12>-0.0058</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.1977</PDBx:U22>
         <PDBx:U23>0.0219</PDBx:U23>
         <PDBx:U33>0.2414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1258">
         <PDBx:U11>0.2297</PDBx:U11>
         <PDBx:U12>0.0110</PDBx:U12>
         <PDBx:U13>-0.0464</PDBx:U13>
         <PDBx:U22>0.2483</PDBx:U22>
         <PDBx:U23>0.0221</PDBx:U23>
         <PDBx:U33>0.2271</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1259">
         <PDBx:U11>0.2188</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>-0.0175</PDBx:U13>
         <PDBx:U22>0.2194</PDBx:U22>
         <PDBx:U23>0.0355</PDBx:U23>
         <PDBx:U33>0.2153</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1260">
         <PDBx:U11>0.2274</PDBx:U11>
         <PDBx:U12>0.0097</PDBx:U12>
         <PDBx:U13>-0.0181</PDBx:U13>
         <PDBx:U22>0.2455</PDBx:U22>
         <PDBx:U23>0.0168</PDBx:U23>
         <PDBx:U33>0.1919</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1261">
         <PDBx:U11>0.2285</PDBx:U11>
         <PDBx:U12>-0.0120</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.2554</PDBx:U22>
         <PDBx:U23>0.0150</PDBx:U23>
         <PDBx:U33>0.2517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1262">
         <PDBx:U11>0.2064</PDBx:U11>
         <PDBx:U12>-0.0113</PDBx:U12>
         <PDBx:U13>-0.0210</PDBx:U13>
         <PDBx:U22>0.2306</PDBx:U22>
         <PDBx:U23>0.0441</PDBx:U23>
         <PDBx:U33>0.2222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1263">
         <PDBx:U11>0.2744</PDBx:U11>
         <PDBx:U12>-0.0239</PDBx:U12>
         <PDBx:U13>-0.0440</PDBx:U13>
         <PDBx:U22>0.2584</PDBx:U22>
         <PDBx:U23>0.0410</PDBx:U23>
         <PDBx:U33>0.2378</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1264">
         <PDBx:U11>0.2131</PDBx:U11>
         <PDBx:U12>0.0001</PDBx:U12>
         <PDBx:U13>-0.0112</PDBx:U13>
         <PDBx:U22>0.2321</PDBx:U22>
         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.2103</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1265">
         <PDBx:U11>0.2257</PDBx:U11>
         <PDBx:U12>0.0049</PDBx:U12>
         <PDBx:U13>-0.0202</PDBx:U13>
         <PDBx:U22>0.2260</PDBx:U22>
         <PDBx:U23>0.0117</PDBx:U23>
         <PDBx:U33>0.2271</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1266">
         <PDBx:U11>0.2406</PDBx:U11>
         <PDBx:U12>-0.0072</PDBx:U12>
         <PDBx:U13>0.0403</PDBx:U13>
         <PDBx:U22>0.2273</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.2256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>552</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1267">
         <PDBx:U11>0.2825</PDBx:U11>
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         <PDBx:U33>0.5791</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>554</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1284">
         <PDBx:U11>0.5979</PDBx:U11>
         <PDBx:U12>0.0133</PDBx:U12>
         <PDBx:U13>0.0505</PDBx:U13>
         <PDBx:U22>0.8072</PDBx:U22>
         <PDBx:U23>-0.0546</PDBx:U23>
         <PDBx:U33>0.6990</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>554</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1285">
         <PDBx:U11>0.3637</PDBx:U11>
         <PDBx:U12>-0.0229</PDBx:U12>
         <PDBx:U13>-0.0699</PDBx:U13>
         <PDBx:U22>0.2944</PDBx:U22>
         <PDBx:U23>0.0244</PDBx:U23>
         <PDBx:U33>0.4248</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>555</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1286">
         <PDBx:U11>0.4179</PDBx:U11>
         <PDBx:U12>-0.0906</PDBx:U12>
         <PDBx:U13>-0.0581</PDBx:U13>
         <PDBx:U22>0.3572</PDBx:U22>
         <PDBx:U23>-0.0432</PDBx:U23>
         <PDBx:U33>0.4223</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>555</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1287">
         <PDBx:U11>0.3582</PDBx:U11>
         <PDBx:U12>-0.0685</PDBx:U12>
         <PDBx:U13>-0.0298</PDBx:U13>
         <PDBx:U22>0.3584</PDBx:U22>
         <PDBx:U23>0.0257</PDBx:U23>
         <PDBx:U33>0.3720</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>555</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1288">
         <PDBx:U11>0.3229</PDBx:U11>
         <PDBx:U12>-0.0682</PDBx:U12>
         <PDBx:U13>-0.0564</PDBx:U13>
         <PDBx:U22>0.3979</PDBx:U22>
         <PDBx:U23>0.0163</PDBx:U23>
         <PDBx:U33>0.4101</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>555</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1289">
         <PDBx:U11>0.3672</PDBx:U11>
         <PDBx:U12>-0.0736</PDBx:U12>
         <PDBx:U13>-0.0594</PDBx:U13>
         <PDBx:U22>0.3339</PDBx:U22>
         <PDBx:U23>0.0090</PDBx:U23>
         <PDBx:U33>0.3759</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>555</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1290">
         <PDBx:U11>0.3861</PDBx:U11>
         <PDBx:U12>-0.0723</PDBx:U12>
         <PDBx:U13>-0.0321</PDBx:U13>
         <PDBx:U22>0.4294</PDBx:U22>
         <PDBx:U23>-0.0805</PDBx:U23>
         <PDBx:U33>0.5101</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>555</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1291">
         <PDBx:U11>0.3683</PDBx:U11>
         <PDBx:U12>-0.0654</PDBx:U12>
         <PDBx:U13>-0.1115</PDBx:U13>
         <PDBx:U22>0.4010</PDBx:U22>
         <PDBx:U23>0.0320</PDBx:U23>
         <PDBx:U33>0.3723</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>555</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1292">
         <PDBx:U11>0.3646</PDBx:U11>
         <PDBx:U12>-0.0769</PDBx:U12>
         <PDBx:U13>-0.0565</PDBx:U13>
         <PDBx:U22>0.3228</PDBx:U22>
         <PDBx:U23>0.0138</PDBx:U23>
         <PDBx:U33>0.3458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>556</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1293">
         <PDBx:U11>0.2590</PDBx:U11>
         <PDBx:U12>-0.0715</PDBx:U12>
         <PDBx:U13>-0.0745</PDBx:U13>
         <PDBx:U22>0.3070</PDBx:U22>
         <PDBx:U23>0.0431</PDBx:U23>
         <PDBx:U33>0.3430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>556</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1294">
         <PDBx:U11>0.3027</PDBx:U11>
         <PDBx:U12>-0.0601</PDBx:U12>
         <PDBx:U13>-0.0429</PDBx:U13>
         <PDBx:U22>0.2853</PDBx:U22>
         <PDBx:U23>0.0135</PDBx:U23>
         <PDBx:U33>0.3576</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>556</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1295">
         <PDBx:U11>0.3701</PDBx:U11>
         <PDBx:U12>-0.0474</PDBx:U12>
         <PDBx:U13>-0.0574</PDBx:U13>
         <PDBx:U22>0.3301</PDBx:U22>
         <PDBx:U23>0.0812</PDBx:U23>
         <PDBx:U33>0.3546</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>556</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1296">
         <PDBx:U11>0.2783</PDBx:U11>
         <PDBx:U12>-0.0605</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.3814</PDBx:U22>
         <PDBx:U23>0.0178</PDBx:U23>
         <PDBx:U33>0.3248</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>557</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1297">
         <PDBx:U11>0.2675</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>0.0090</PDBx:U13>
         <PDBx:U22>0.3604</PDBx:U22>
         <PDBx:U23>0.0080</PDBx:U23>
         <PDBx:U33>0.3500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>557</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1298">
         <PDBx:U11>0.2928</PDBx:U11>
         <PDBx:U12>-0.0081</PDBx:U12>
         <PDBx:U13>-0.0189</PDBx:U13>
         <PDBx:U22>0.4485</PDBx:U22>
         <PDBx:U23>0.1133</PDBx:U23>
         <PDBx:U33>0.3369</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>557</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1299">
         <PDBx:U11>0.3512</PDBx:U11>
         <PDBx:U12>-0.0061</PDBx:U12>
         <PDBx:U13>0.0430</PDBx:U13>
         <PDBx:U22>0.4805</PDBx:U22>
         <PDBx:U23>0.1398</PDBx:U23>
         <PDBx:U33>0.3352</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>557</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1300">
         <PDBx:U11>0.2710</PDBx:U11>
         <PDBx:U12>0.0302</PDBx:U12>
         <PDBx:U13>0.0431</PDBx:U13>
         <PDBx:U22>0.3781</PDBx:U22>
         <PDBx:U23>0.0397</PDBx:U23>
         <PDBx:U33>0.3830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>557</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1301">
         <PDBx:U11>0.2748</PDBx:U11>
         <PDBx:U12>0.0410</PDBx:U12>
         <PDBx:U13>0.0211</PDBx:U13>
         <PDBx:U22>0.4153</PDBx:U22>
         <PDBx:U23>0.1204</PDBx:U23>
         <PDBx:U33>0.4594</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>557</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1302">
         <PDBx:U11>0.2497</PDBx:U11>
         <PDBx:U12>0.0321</PDBx:U12>
         <PDBx:U13>0.0397</PDBx:U13>
         <PDBx:U22>0.3218</PDBx:U22>
         <PDBx:U23>0.0361</PDBx:U23>
         <PDBx:U33>0.3255</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>558</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1303">
         <PDBx:U11>0.2563</PDBx:U11>
         <PDBx:U12>0.0628</PDBx:U12>
         <PDBx:U13>0.0437</PDBx:U13>
         <PDBx:U22>0.2909</PDBx:U22>
         <PDBx:U23>0.0242</PDBx:U23>
         <PDBx:U33>0.3345</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>558</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1304">
         <PDBx:U11>0.2104</PDBx:U11>
         <PDBx:U12>0.0242</PDBx:U12>
         <PDBx:U13>0.0127</PDBx:U13>
         <PDBx:U22>0.2574</PDBx:U22>
         <PDBx:U23>0.0210</PDBx:U23>
         <PDBx:U33>0.1833</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>558</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1305">
         <PDBx:U11>0.2314</PDBx:U11>
         <PDBx:U12>0.0070</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.2508</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.2445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>558</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1306">
         <PDBx:U11>0.2670</PDBx:U11>
         <PDBx:U12>0.0626</PDBx:U12>
         <PDBx:U13>0.0354</PDBx:U13>
         <PDBx:U22>0.2799</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.3220</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>558</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1307">
         <PDBx:U11>0.2598</PDBx:U11>
         <PDBx:U12>0.0684</PDBx:U12>
         <PDBx:U13>0.0182</PDBx:U13>
         <PDBx:U22>0.3049</PDBx:U22>
         <PDBx:U23>0.0055</PDBx:U23>
         <PDBx:U33>0.3080</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>558</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1308">
         <PDBx:U11>0.2656</PDBx:U11>
         <PDBx:U12>0.0698</PDBx:U12>
         <PDBx:U13>-0.0172</PDBx:U13>
         <PDBx:U22>0.2987</PDBx:U22>
         <PDBx:U23>-0.0137</PDBx:U23>
         <PDBx:U33>0.4195</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>558</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1309">
         <PDBx:U11>0.2623</PDBx:U11>
         <PDBx:U12>0.0895</PDBx:U12>
         <PDBx:U13>-0.0124</PDBx:U13>
         <PDBx:U22>0.3312</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.4137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>558</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1310">
         <PDBx:U11>0.3900</PDBx:U11>
         <PDBx:U12>0.0928</PDBx:U12>
         <PDBx:U13>0.0304</PDBx:U13>
         <PDBx:U22>0.3898</PDBx:U22>
         <PDBx:U23>0.0089</PDBx:U23>
         <PDBx:U33>0.3576</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>558</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1311">
         <PDBx:U11>0.2239</PDBx:U11>
         <PDBx:U12>0.0502</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.2819</PDBx:U22>
         <PDBx:U23>0.0262</PDBx:U23>
         <PDBx:U33>0.2180</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>559</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1312">
         <PDBx:U11>0.2115</PDBx:U11>
         <PDBx:U12>0.0582</PDBx:U12>
         <PDBx:U13>-0.0156</PDBx:U13>
         <PDBx:U22>0.2380</PDBx:U22>
         <PDBx:U23>0.0063</PDBx:U23>
         <PDBx:U33>0.2154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>559</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1313">
         <PDBx:U11>0.2240</PDBx:U11>
         <PDBx:U12>-0.0174</PDBx:U12>
         <PDBx:U13>-0.0262</PDBx:U13>
         <PDBx:U22>0.2193</PDBx:U22>
         <PDBx:U23>0.0052</PDBx:U23>
         <PDBx:U33>0.2035</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>559</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1314">
         <PDBx:U11>0.2061</PDBx:U11>
         <PDBx:U12>0.0137</PDBx:U12>
         <PDBx:U13>0.0118</PDBx:U13>
         <PDBx:U22>0.2774</PDBx:U22>
         <PDBx:U23>0.0167</PDBx:U23>
         <PDBx:U33>0.2064</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>559</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1315">
         <PDBx:U11>0.2539</PDBx:U11>
         <PDBx:U12>0.0634</PDBx:U12>
         <PDBx:U13>-0.0117</PDBx:U13>
         <PDBx:U22>0.2632</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.1867</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>559</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1316">
         <PDBx:U11>0.2212</PDBx:U11>
         <PDBx:U12>0.0136</PDBx:U12>
         <PDBx:U13>-0.0042</PDBx:U13>
         <PDBx:U22>0.2451</PDBx:U22>
         <PDBx:U23>-0.0148</PDBx:U23>
         <PDBx:U33>0.1882</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>559</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1317">
         <PDBx:U11>0.2505</PDBx:U11>
         <PDBx:U12>-0.0081</PDBx:U12>
         <PDBx:U13>0.0090</PDBx:U13>
         <PDBx:U22>0.2656</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.2091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>559</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1318">
         <PDBx:U11>0.2438</PDBx:U11>
         <PDBx:U12>0.0098</PDBx:U12>
         <PDBx:U13>-0.0490</PDBx:U13>
         <PDBx:U22>0.2591</PDBx:U22>
         <PDBx:U23>-0.0114</PDBx:U23>
         <PDBx:U33>0.2210</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>559</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1319">
         <PDBx:U11>0.2298</PDBx:U11>
         <PDBx:U12>0.0072</PDBx:U12>
         <PDBx:U13>-0.0227</PDBx:U13>
         <PDBx:U22>0.2217</PDBx:U22>
         <PDBx:U23>-0.0277</PDBx:U23>
         <PDBx:U33>0.2302</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>559</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1320">
         <PDBx:U11>0.2538</PDBx:U11>
         <PDBx:U12>-0.0146</PDBx:U12>
         <PDBx:U13>0.0082</PDBx:U13>
         <PDBx:U22>0.2446</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.1981</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>559</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1321">
         <PDBx:U11>0.2693</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.2306</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.2032</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>559</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1322">
         <PDBx:U11>0.1983</PDBx:U11>
         <PDBx:U12>-0.0080</PDBx:U12>
         <PDBx:U13>0.0191</PDBx:U13>
         <PDBx:U22>0.2090</PDBx:U22>
         <PDBx:U23>0.0130</PDBx:U23>
         <PDBx:U33>0.1958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>560</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1323">
         <PDBx:U11>0.1838</PDBx:U11>
         <PDBx:U12>-0.0315</PDBx:U12>
         <PDBx:U13>-0.0028</PDBx:U13>
         <PDBx:U22>0.2049</PDBx:U22>
         <PDBx:U23>0.0358</PDBx:U23>
         <PDBx:U33>0.2272</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>560</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1324">
         <PDBx:U11>0.1922</PDBx:U11>
         <PDBx:U12>0.0086</PDBx:U12>
         <PDBx:U13>-0.0126</PDBx:U13>
         <PDBx:U22>0.2178</PDBx:U22>
         <PDBx:U23>-0.0133</PDBx:U23>
         <PDBx:U33>0.1651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>560</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1325">
         <PDBx:U11>0.1997</PDBx:U11>
         <PDBx:U12>0.0017</PDBx:U12>
         <PDBx:U13>-0.0229</PDBx:U13>
         <PDBx:U22>0.2042</PDBx:U22>
         <PDBx:U23>0.0056</PDBx:U23>
         <PDBx:U33>0.1987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>560</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1326">
         <PDBx:U11>0.2145</PDBx:U11>
         <PDBx:U12>-0.0425</PDBx:U12>
         <PDBx:U13>-0.0205</PDBx:U13>
         <PDBx:U22>0.2496</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.1620</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>560</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1327">
         <PDBx:U11>0.2446</PDBx:U11>
         <PDBx:U12>0.0121</PDBx:U12>
         <PDBx:U13>-0.0313</PDBx:U13>
         <PDBx:U22>0.2670</PDBx:U22>
         <PDBx:U23>0.0402</PDBx:U23>
         <PDBx:U33>0.1676</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>560</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1328">
         <PDBx:U11>0.1655</PDBx:U11>
         <PDBx:U12>-0.0035</PDBx:U12>
         <PDBx:U13>0.0181</PDBx:U13>
         <PDBx:U22>0.2075</PDBx:U22>
         <PDBx:U23>0.0205</PDBx:U23>
         <PDBx:U33>0.2040</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>560</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1329">
         <PDBx:U11>0.2063</PDBx:U11>
         <PDBx:U12>-0.0199</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.2177</PDBx:U22>
         <PDBx:U23>0.0115</PDBx:U23>
         <PDBx:U33>0.1627</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>561</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1330">
         <PDBx:U11>0.2070</PDBx:U11>
         <PDBx:U12>-0.0040</PDBx:U12>
         <PDBx:U13>-0.0500</PDBx:U13>
         <PDBx:U22>0.2269</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.2094</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>561</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1331">
         <PDBx:U11>0.1722</PDBx:U11>
         <PDBx:U12>-0.0066</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.2258</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.1862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>561</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1332">
         <PDBx:U11>0.1908</PDBx:U11>
         <PDBx:U12>0.0042</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.2217</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.1891</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>561</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1333">
         <PDBx:U11>0.2206</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>-0.0440</PDBx:U13>
         <PDBx:U22>0.2377</PDBx:U22>
         <PDBx:U23>0.0371</PDBx:U23>
         <PDBx:U33>0.2157</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>561</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1334">
         <PDBx:U11>0.2046</PDBx:U11>
         <PDBx:U12>-0.0233</PDBx:U12>
         <PDBx:U13>0.0131</PDBx:U13>
         <PDBx:U22>0.2588</PDBx:U22>
         <PDBx:U23>-0.0208</PDBx:U23>
         <PDBx:U33>0.2166</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>561</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1335">
         <PDBx:U11>0.2402</PDBx:U11>
         <PDBx:U12>-0.0498</PDBx:U12>
         <PDBx:U13>-0.0846</PDBx:U13>
         <PDBx:U22>0.2638</PDBx:U22>
         <PDBx:U23>0.0088</PDBx:U23>
         <PDBx:U33>0.2105</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>561</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1336">
         <PDBx:U11>0.1970</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.1970</PDBx:U22>
         <PDBx:U23>-0.0053</PDBx:U23>
         <PDBx:U33>0.1676</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>562</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1337">
         <PDBx:U11>0.1977</PDBx:U11>
         <PDBx:U12>0.0121</PDBx:U12>
         <PDBx:U13>0.0166</PDBx:U13>
         <PDBx:U22>0.2067</PDBx:U22>
         <PDBx:U23>-0.0118</PDBx:U23>
         <PDBx:U33>0.1615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>562</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1338">
         <PDBx:U11>0.2092</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>-0.0125</PDBx:U13>
         <PDBx:U22>0.2135</PDBx:U22>
         <PDBx:U23>-0.0260</PDBx:U23>
         <PDBx:U33>0.1428</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>562</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1339">
         <PDBx:U11>0.1944</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.1962</PDBx:U22>
         <PDBx:U23>0.0158</PDBx:U23>
         <PDBx:U33>0.1848</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>562</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1340">
         <PDBx:U11>0.1606</PDBx:U11>
         <PDBx:U12>-0.0208</PDBx:U12>
         <PDBx:U13>0.0359</PDBx:U13>
         <PDBx:U22>0.1977</PDBx:U22>
         <PDBx:U23>-0.0163</PDBx:U23>
         <PDBx:U33>0.1742</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>562</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1341">
         <PDBx:U11>0.1736</PDBx:U11>
         <PDBx:U12>-0.0176</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.2123</PDBx:U22>
         <PDBx:U23>-0.0231</PDBx:U23>
         <PDBx:U33>0.1840</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>562</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1342">
         <PDBx:U11>0.1975</PDBx:U11>
         <PDBx:U12>-0.0151</PDBx:U12>
         <PDBx:U13>0.0141</PDBx:U13>
         <PDBx:U22>0.2093</PDBx:U22>
         <PDBx:U23>-0.0095</PDBx:U23>
         <PDBx:U33>0.1956</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>562</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1343">
         <PDBx:U11>0.1962</PDBx:U11>
         <PDBx:U12>0.0103</PDBx:U12>
         <PDBx:U13>-0.0129</PDBx:U13>
         <PDBx:U22>0.2280</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.1945</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>562</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1344">
         <PDBx:U11>0.1955</PDBx:U11>
         <PDBx:U12>0.0048</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.2425</PDBx:U22>
         <PDBx:U23>0.0255</PDBx:U23>
         <PDBx:U33>0.2134</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>562</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1345">
         <PDBx:U11>0.2034</PDBx:U11>
         <PDBx:U12>0.0116</PDBx:U12>
         <PDBx:U13>-0.0160</PDBx:U13>
         <PDBx:U22>0.2752</PDBx:U22>
         <PDBx:U23>0.0148</PDBx:U23>
         <PDBx:U33>0.2069</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>562</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1346">
         <PDBx:U11>0.2162</PDBx:U11>
         <PDBx:U12>0.0153</PDBx:U12>
         <PDBx:U13>-0.0043</PDBx:U13>
         <PDBx:U22>0.2069</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.1821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>562</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1347">
         <PDBx:U11>0.1947</PDBx:U11>
         <PDBx:U12>-0.0032</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1895</PDBx:U22>
         <PDBx:U23>-0.0247</PDBx:U23>
         <PDBx:U33>0.1676</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>563</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1348">
         <PDBx:U11>0.1929</PDBx:U11>
         <PDBx:U12>-0.0094</PDBx:U12>
         <PDBx:U13>0.0145</PDBx:U13>
         <PDBx:U22>0.1656</PDBx:U22>
         <PDBx:U23>-0.0279</PDBx:U23>
         <PDBx:U33>0.1857</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>563</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>565</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
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         <PDBx:U23>-0.0213</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>565</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>565</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
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         <PDBx:U23>0.0149</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>565</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0113</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>565</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0314</PDBx:U13>
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         <PDBx:U23>-0.0077</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>565</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0098</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>566</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>-0.0238</PDBx:U13>
         <PDBx:U22>0.2136</PDBx:U22>
         <PDBx:U23>0.0053</PDBx:U23>
         <PDBx:U33>0.1967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>566</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.2096</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>566</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0140</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>566</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0568</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>566</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0770</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>566</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>566</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.0291</PDBx:U12>
         <PDBx:U13>0.0169</PDBx:U13>
         <PDBx:U22>0.1842</PDBx:U22>
         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.1958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>567</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1382">
         <PDBx:U11>0.2300</PDBx:U11>
         <PDBx:U12>0.0076</PDBx:U12>
         <PDBx:U13>-0.0141</PDBx:U13>
         <PDBx:U22>0.1764</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.1908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>567</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1383">
         <PDBx:U11>0.2283</PDBx:U11>
         <PDBx:U12>0.0200</PDBx:U12>
         <PDBx:U13>-0.0046</PDBx:U13>
         <PDBx:U22>0.1736</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.1972</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>567</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1384">
         <PDBx:U11>0.2123</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>-0.0027</PDBx:U13>
         <PDBx:U22>0.2123</PDBx:U22>
         <PDBx:U23>-0.0221</PDBx:U23>
         <PDBx:U33>0.1940</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>567</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1385">
         <PDBx:U11>0.2361</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>0.0271</PDBx:U13>
         <PDBx:U22>0.2078</PDBx:U22>
         <PDBx:U23>-0.0438</PDBx:U23>
         <PDBx:U33>0.1778</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>567</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1386">
         <PDBx:U11>0.1918</PDBx:U11>
         <PDBx:U12>-0.0100</PDBx:U12>
         <PDBx:U13>0.0152</PDBx:U13>
         <PDBx:U22>0.2245</PDBx:U22>
         <PDBx:U23>-0.0160</PDBx:U23>
         <PDBx:U33>0.1941</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>567</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1387">
         <PDBx:U11>0.2494</PDBx:U11>
         <PDBx:U12>0.0264</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.1834</PDBx:U22>
         <PDBx:U23>-0.0193</PDBx:U23>
         <PDBx:U33>0.2328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>567</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1388">
         <PDBx:U11>0.2210</PDBx:U11>
         <PDBx:U12>0.0046</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.2095</PDBx:U22>
         <PDBx:U23>-0.0216</PDBx:U23>
         <PDBx:U33>0.2135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>567</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1389">
         <PDBx:U11>0.2312</PDBx:U11>
         <PDBx:U12>0.0130</PDBx:U12>
         <PDBx:U13>-0.0096</PDBx:U13>
         <PDBx:U22>0.2120</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.1961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>567</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1390">
         <PDBx:U11>0.2184</PDBx:U11>
         <PDBx:U12>0.0125</PDBx:U12>
         <PDBx:U13>0.0222</PDBx:U13>
         <PDBx:U22>0.1805</PDBx:U22>
         <PDBx:U23>-0.0129</PDBx:U23>
         <PDBx:U33>0.2001</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>568</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1391">
         <PDBx:U11>0.2243</PDBx:U11>
         <PDBx:U12>0.0130</PDBx:U12>
         <PDBx:U13>0.0117</PDBx:U13>
         <PDBx:U22>0.1952</PDBx:U22>
         <PDBx:U23>-0.0238</PDBx:U23>
         <PDBx:U33>0.1578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>568</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1392">
         <PDBx:U11>0.2263</PDBx:U11>
         <PDBx:U12>0.0018</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.2100</PDBx:U22>
         <PDBx:U23>-0.0104</PDBx:U23>
         <PDBx:U33>0.2056</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>568</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1393">
         <PDBx:U11>0.2343</PDBx:U11>
         <PDBx:U12>0.0075</PDBx:U12>
         <PDBx:U13>0.0158</PDBx:U13>
         <PDBx:U22>0.2149</PDBx:U22>
         <PDBx:U23>-0.0414</PDBx:U23>
         <PDBx:U33>0.2067</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>568</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1394">
         <PDBx:U11>0.2074</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>-0.0040</PDBx:U13>
         <PDBx:U22>0.1674</PDBx:U22>
         <PDBx:U23>-0.0132</PDBx:U23>
         <PDBx:U33>0.1696</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>568</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1395">
         <PDBx:U11>0.2197</PDBx:U11>
         <PDBx:U12>0.0067</PDBx:U12>
         <PDBx:U13>0.0115</PDBx:U13>
         <PDBx:U22>0.1995</PDBx:U22>
         <PDBx:U23>-0.0238</PDBx:U23>
         <PDBx:U33>0.2072</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>568</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1396">
         <PDBx:U11>0.1978</PDBx:U11>
         <PDBx:U12>-0.0152</PDBx:U12>
         <PDBx:U13>-0.0193</PDBx:U13>
         <PDBx:U22>0.2181</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.1965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>568</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1397">
         <PDBx:U11>0.1956</PDBx:U11>
         <PDBx:U12>-0.0259</PDBx:U12>
         <PDBx:U13>0.0100</PDBx:U13>
         <PDBx:U22>0.2137</PDBx:U22>
         <PDBx:U23>-0.0404</PDBx:U23>
         <PDBx:U33>0.1971</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>569</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1398">
         <PDBx:U11>0.1998</PDBx:U11>
         <PDBx:U12>-0.0318</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.2559</PDBx:U22>
         <PDBx:U23>-0.0208</PDBx:U23>
         <PDBx:U33>0.1924</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>569</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1399">
         <PDBx:U11>0.2076</PDBx:U11>
         <PDBx:U12>-0.0213</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.2419</PDBx:U22>
         <PDBx:U23>-0.0157</PDBx:U23>
         <PDBx:U33>0.2104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>569</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1400">
         <PDBx:U11>0.2511</PDBx:U11>
         <PDBx:U12>0.0111</PDBx:U12>
         <PDBx:U13>-0.0382</PDBx:U13>
         <PDBx:U22>0.2578</PDBx:U22>
         <PDBx:U23>-0.0249</PDBx:U23>
         <PDBx:U33>0.2370</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>569</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1401">
         <PDBx:U11>0.2328</PDBx:U11>
         <PDBx:U12>-0.0516</PDBx:U12>
         <PDBx:U13>0.0353</PDBx:U13>
         <PDBx:U22>0.2704</PDBx:U22>
         <PDBx:U23>-0.0363</PDBx:U23>
         <PDBx:U33>0.1859</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>569</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1402">
         <PDBx:U11>0.2720</PDBx:U11>
         <PDBx:U12>-0.0339</PDBx:U12>
         <PDBx:U13>-0.0043</PDBx:U13>
         <PDBx:U22>0.2492</PDBx:U22>
         <PDBx:U23>-0.0331</PDBx:U23>
         <PDBx:U33>0.1990</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>569</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1403">
         <PDBx:U11>0.3237</PDBx:U11>
         <PDBx:U12>-0.0725</PDBx:U12>
         <PDBx:U13>0.0581</PDBx:U13>
         <PDBx:U22>0.3217</PDBx:U22>
         <PDBx:U23>0.0089</PDBx:U23>
         <PDBx:U33>0.2814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>569</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1404">
         <PDBx:U11>0.2591</PDBx:U11>
         <PDBx:U12>0.0165</PDBx:U12>
         <PDBx:U13>0.0077</PDBx:U13>
         <PDBx:U22>0.2882</PDBx:U22>
         <PDBx:U23>-0.0569</PDBx:U23>
         <PDBx:U33>0.2107</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>569</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1405">
         <PDBx:U11>0.2418</PDBx:U11>
         <PDBx:U12>-0.0303</PDBx:U12>
         <PDBx:U13>0.0245</PDBx:U13>
         <PDBx:U22>0.2246</PDBx:U22>
         <PDBx:U23>-0.0427</PDBx:U23>
         <PDBx:U33>0.1864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>570</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1406">
         <PDBx:U11>0.2731</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>-0.0090</PDBx:U13>
         <PDBx:U22>0.2525</PDBx:U22>
         <PDBx:U23>-0.0327</PDBx:U23>
         <PDBx:U33>0.1633</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>570</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1407">
         <PDBx:U11>0.2245</PDBx:U11>
         <PDBx:U12>-0.0607</PDBx:U12>
         <PDBx:U13>0.0077</PDBx:U13>
         <PDBx:U22>0.2667</PDBx:U22>
         <PDBx:U23>0.0131</PDBx:U23>
         <PDBx:U33>0.2189</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>570</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1408">
         <PDBx:U11>0.2694</PDBx:U11>
         <PDBx:U12>-0.0454</PDBx:U12>
         <PDBx:U13>0.0224</PDBx:U13>
         <PDBx:U22>0.3110</PDBx:U22>
         <PDBx:U23>-0.0100</PDBx:U23>
         <PDBx:U33>0.2110</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>570</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1409">
         <PDBx:U11>0.2450</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>0.0168</PDBx:U13>
         <PDBx:U22>0.2663</PDBx:U22>
         <PDBx:U23>-0.0219</PDBx:U23>
         <PDBx:U33>0.1996</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>570</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1410">
         <PDBx:U11>0.3779</PDBx:U11>
         <PDBx:U12>0.0062</PDBx:U12>
         <PDBx:U13>0.0927</PDBx:U13>
         <PDBx:U22>0.3189</PDBx:U22>
         <PDBx:U23>0.0048</PDBx:U23>
         <PDBx:U33>0.2519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>570</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1411">
         <PDBx:U11>0.5595</PDBx:U11>
         <PDBx:U12>-0.0047</PDBx:U12>
         <PDBx:U13>0.0722</PDBx:U13>
         <PDBx:U22>0.3694</PDBx:U22>
         <PDBx:U23>0.0292</PDBx:U23>
         <PDBx:U33>0.4639</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>570</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1412">
         <PDBx:U11>0.5599</PDBx:U11>
         <PDBx:U12>0.0127</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.3494</PDBx:U22>
         <PDBx:U23>0.0463</PDBx:U23>
         <PDBx:U33>0.4700</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>570</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1413">
         <PDBx:U11>0.1966</PDBx:U11>
         <PDBx:U12>-0.0255</PDBx:U12>
         <PDBx:U13>0.0208</PDBx:U13>
         <PDBx:U22>0.2502</PDBx:U22>
         <PDBx:U23>-0.0279</PDBx:U23>
         <PDBx:U33>0.1644</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>571</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1414">
         <PDBx:U11>0.2110</PDBx:U11>
         <PDBx:U12>-0.0256</PDBx:U12>
         <PDBx:U13>0.0185</PDBx:U13>
         <PDBx:U22>0.2230</PDBx:U22>
         <PDBx:U23>-0.0106</PDBx:U23>
         <PDBx:U33>0.1685</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>571</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1415">
         <PDBx:U11>0.2241</PDBx:U11>
         <PDBx:U12>0.0045</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.2143</PDBx:U22>
         <PDBx:U23>-0.0159</PDBx:U23>
         <PDBx:U33>0.1861</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>571</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1416">
         <PDBx:U11>0.2124</PDBx:U11>
         <PDBx:U12>-0.0271</PDBx:U12>
         <PDBx:U13>0.0138</PDBx:U13>
         <PDBx:U22>0.2469</PDBx:U22>
         <PDBx:U23>-0.0097</PDBx:U23>
         <PDBx:U33>0.2015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>571</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1417">
         <PDBx:U11>0.2708</PDBx:U11>
         <PDBx:U12>0.0052</PDBx:U12>
         <PDBx:U13>0.0201</PDBx:U13>
         <PDBx:U22>0.2202</PDBx:U22>
         <PDBx:U23>-0.0312</PDBx:U23>
         <PDBx:U33>0.2197</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>571</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1418">
         <PDBx:U11>0.2478</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>0.0126</PDBx:U13>
         <PDBx:U22>0.2365</PDBx:U22>
         <PDBx:U23>-0.0176</PDBx:U23>
         <PDBx:U33>0.1995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>571</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1419">
         <PDBx:U11>0.3011</PDBx:U11>
         <PDBx:U12>0.0536</PDBx:U12>
         <PDBx:U13>0.0095</PDBx:U13>
         <PDBx:U22>0.2366</PDBx:U22>
         <PDBx:U23>-0.0148</PDBx:U23>
         <PDBx:U33>0.2486</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>571</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1420">
         <PDBx:U11>0.2723</PDBx:U11>
         <PDBx:U12>-0.0344</PDBx:U12>
         <PDBx:U13>0.0370</PDBx:U13>
         <PDBx:U22>0.2675</PDBx:U22>
         <PDBx:U23>-0.0525</PDBx:U23>
         <PDBx:U33>0.2121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>571</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1421">
         <PDBx:U11>0.3547</PDBx:U11>
         <PDBx:U12>0.0061</PDBx:U12>
         <PDBx:U13>0.0294</PDBx:U13>
         <PDBx:U22>0.2560</PDBx:U22>
         <PDBx:U23>-0.0306</PDBx:U23>
         <PDBx:U33>0.3012</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>571</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1422">
         <PDBx:U11>0.3004</PDBx:U11>
         <PDBx:U12>-0.0384</PDBx:U12>
         <PDBx:U13>0.0601</PDBx:U13>
         <PDBx:U22>0.2626</PDBx:U22>
         <PDBx:U23>-0.0669</PDBx:U23>
         <PDBx:U33>0.2813</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>571</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1423">
         <PDBx:U11>0.3360</PDBx:U11>
         <PDBx:U12>-0.0334</PDBx:U12>
         <PDBx:U13>0.0631</PDBx:U13>
         <PDBx:U22>0.2401</PDBx:U22>
         <PDBx:U23>-0.0115</PDBx:U23>
         <PDBx:U33>0.3425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>571</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1424">
         <PDBx:U11>0.4275</PDBx:U11>
         <PDBx:U12>-0.0666</PDBx:U12>
         <PDBx:U13>0.1317</PDBx:U13>
         <PDBx:U22>0.2504</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.4490</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>571</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1425">
         <PDBx:U11>0.2286</PDBx:U11>
         <PDBx:U12>-0.0299</PDBx:U12>
         <PDBx:U13>-0.0053</PDBx:U13>
         <PDBx:U22>0.2131</PDBx:U22>
         <PDBx:U23>-0.0283</PDBx:U23>
         <PDBx:U33>0.1862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>572</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1426">
         <PDBx:U11>0.2159</PDBx:U11>
         <PDBx:U12>-0.0070</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.1974</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.1903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>572</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1427">
         <PDBx:U11>0.2148</PDBx:U11>
         <PDBx:U12>0.0083</PDBx:U12>
         <PDBx:U13>-0.0201</PDBx:U13>
         <PDBx:U22>0.2553</PDBx:U22>
         <PDBx:U23>0.0136</PDBx:U23>
         <PDBx:U33>0.1672</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>572</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1428">
         <PDBx:U11>0.2168</PDBx:U11>
         <PDBx:U12>0.0027</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.2333</PDBx:U22>
         <PDBx:U23>0.0171</PDBx:U23>
         <PDBx:U33>0.2281</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>572</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1429">
         <PDBx:U11>0.2111</PDBx:U11>
         <PDBx:U12>0.0408</PDBx:U12>
         <PDBx:U13>-0.0077</PDBx:U13>
         <PDBx:U22>0.2652</PDBx:U22>
         <PDBx:U23>0.0112</PDBx:U23>
         <PDBx:U33>0.2155</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>572</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1430">
         <PDBx:U11>0.2308</PDBx:U11>
         <PDBx:U12>0.0233</PDBx:U12>
         <PDBx:U13>0.0036</PDBx:U13>
         <PDBx:U22>0.2861</PDBx:U22>
         <PDBx:U23>0.0517</PDBx:U23>
         <PDBx:U33>0.3121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>572</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1431">
         <PDBx:U11>0.2141</PDBx:U11>
         <PDBx:U12>0.0100</PDBx:U12>
         <PDBx:U13>-0.0095</PDBx:U13>
         <PDBx:U22>0.1876</PDBx:U22>
         <PDBx:U23>-0.0091</PDBx:U23>
         <PDBx:U33>0.1886</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>573</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1432">
         <PDBx:U11>0.2278</PDBx:U11>
         <PDBx:U12>0.0081</PDBx:U12>
         <PDBx:U13>0.0137</PDBx:U13>
         <PDBx:U22>0.2083</PDBx:U22>
         <PDBx:U23>-0.0304</PDBx:U23>
         <PDBx:U33>0.1645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>573</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1433">
         <PDBx:U11>0.2511</PDBx:U11>
         <PDBx:U12>-0.0103</PDBx:U12>
         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.1804</PDBx:U22>
         <PDBx:U23>-0.0211</PDBx:U23>
         <PDBx:U33>0.1894</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>573</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1434">
         <PDBx:U11>0.2833</PDBx:U11>
         <PDBx:U12>-0.0075</PDBx:U12>
         <PDBx:U13>-0.0139</PDBx:U13>
         <PDBx:U22>0.1781</PDBx:U22>
         <PDBx:U23>-0.0146</PDBx:U23>
         <PDBx:U33>0.2282</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>573</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1435">
         <PDBx:U11>0.2231</PDBx:U11>
         <PDBx:U12>0.0156</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.2005</PDBx:U22>
         <PDBx:U23>-0.0643</PDBx:U23>
         <PDBx:U33>0.2312</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>573</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1436">
         <PDBx:U11>0.2354</PDBx:U11>
         <PDBx:U12>-0.0045</PDBx:U12>
         <PDBx:U13>0.0106</PDBx:U13>
         <PDBx:U22>0.3415</PDBx:U22>
         <PDBx:U23>-0.0170</PDBx:U23>
         <PDBx:U33>0.2912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>573</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1437">
         <PDBx:U11>0.2360</PDBx:U11>
         <PDBx:U12>0.0148</PDBx:U12>
         <PDBx:U13>0.0243</PDBx:U13>
         <PDBx:U22>0.3263</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.2831</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>573</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1438">
         <PDBx:U11>0.3220</PDBx:U11>
         <PDBx:U12>0.0954</PDBx:U12>
         <PDBx:U13>0.0146</PDBx:U13>
         <PDBx:U22>0.2794</PDBx:U22>
         <PDBx:U23>-0.0105</PDBx:U23>
         <PDBx:U33>0.3570</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>573</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1439">
         <PDBx:U11>0.3936</PDBx:U11>
         <PDBx:U12>0.0709</PDBx:U12>
         <PDBx:U13>-0.0650</PDBx:U13>
         <PDBx:U22>0.3895</PDBx:U22>
         <PDBx:U23>0.0458</PDBx:U23>
         <PDBx:U33>0.6511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>573</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1440">
         <PDBx:U11>0.2021</PDBx:U11>
         <PDBx:U12>-0.0245</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.1960</PDBx:U22>
         <PDBx:U23>-0.0180</PDBx:U23>
         <PDBx:U33>0.2010</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>574</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1441">
         <PDBx:U11>0.2381</PDBx:U11>
         <PDBx:U12>0.0063</PDBx:U12>
         <PDBx:U13>-0.0204</PDBx:U13>
         <PDBx:U22>0.1900</PDBx:U22>
         <PDBx:U23>-0.0152</PDBx:U23>
         <PDBx:U33>0.2030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>574</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1442">
         <PDBx:U11>0.2101</PDBx:U11>
         <PDBx:U12>-0.0051</PDBx:U12>
         <PDBx:U13>-0.0139</PDBx:U13>
         <PDBx:U22>0.1992</PDBx:U22>
         <PDBx:U23>0.0042</PDBx:U23>
         <PDBx:U33>0.1821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>574</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1443">
         <PDBx:U11>0.2186</PDBx:U11>
         <PDBx:U12>0.0286</PDBx:U12>
         <PDBx:U13>-0.0113</PDBx:U13>
         <PDBx:U22>0.2507</PDBx:U22>
         <PDBx:U23>0.0078</PDBx:U23>
         <PDBx:U33>0.2121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>574</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1444">
         <PDBx:U11>0.2288</PDBx:U11>
         <PDBx:U12>0.0189</PDBx:U12>
         <PDBx:U13>-0.0021</PDBx:U13>
         <PDBx:U22>0.1937</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.2294</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>574</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1445">
         <PDBx:U11>0.2197</PDBx:U11>
         <PDBx:U12>0.0183</PDBx:U12>
         <PDBx:U13>0.0234</PDBx:U13>
         <PDBx:U22>0.1977</PDBx:U22>
         <PDBx:U23>0.0107</PDBx:U23>
         <PDBx:U33>0.2285</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>574</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1446">
         <PDBx:U11>0.2108</PDBx:U11>
         <PDBx:U12>0.0134</PDBx:U12>
         <PDBx:U13>-0.0090</PDBx:U13>
         <PDBx:U22>0.1821</PDBx:U22>
         <PDBx:U23>0.0237</PDBx:U23>
         <PDBx:U33>0.2543</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>574</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1447">
         <PDBx:U11>0.2715</PDBx:U11>
         <PDBx:U12>0.0056</PDBx:U12>
         <PDBx:U13>0.0194</PDBx:U13>
         <PDBx:U22>0.2750</PDBx:U22>
         <PDBx:U23>0.0314</PDBx:U23>
         <PDBx:U33>0.2127</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>574</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1448">
         <PDBx:U11>0.2222</PDBx:U11>
         <PDBx:U12>0.0170</PDBx:U12>
         <PDBx:U13>-0.0112</PDBx:U13>
         <PDBx:U22>0.2266</PDBx:U22>
         <PDBx:U23>0.0161</PDBx:U23>
         <PDBx:U33>0.2278</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>574</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1449">
         <PDBx:U11>0.2414</PDBx:U11>
         <PDBx:U12>0.0073</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.2374</PDBx:U22>
         <PDBx:U23>0.0454</PDBx:U23>
         <PDBx:U33>0.2452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>574</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1450">
         <PDBx:U11>0.2605</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>0.0158</PDBx:U13>
         <PDBx:U22>0.1978</PDBx:U22>
         <PDBx:U23>0.0063</PDBx:U23>
         <PDBx:U33>0.2450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>574</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1451">
         <PDBx:U11>0.2390</PDBx:U11>
         <PDBx:U12>-0.0271</PDBx:U12>
         <PDBx:U13>-0.0165</PDBx:U13>
         <PDBx:U22>0.1992</PDBx:U22>
         <PDBx:U23>0.0058</PDBx:U23>
         <PDBx:U33>0.1863</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>575</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1452">
         <PDBx:U11>0.2383</PDBx:U11>
         <PDBx:U12>-0.0265</PDBx:U12>
         <PDBx:U13>-0.0206</PDBx:U13>
         <PDBx:U22>0.2318</PDBx:U22>
         <PDBx:U23>-0.0158</PDBx:U23>
         <PDBx:U33>0.1853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>575</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1453">
         <PDBx:U11>0.2126</PDBx:U11>
         <PDBx:U12>-0.0134</PDBx:U12>
         <PDBx:U13>-0.0077</PDBx:U13>
         <PDBx:U22>0.2249</PDBx:U22>
         <PDBx:U23>-0.0252</PDBx:U23>
         <PDBx:U33>0.1718</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>575</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1454">
         <PDBx:U11>0.2071</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.2095</PDBx:U22>
         <PDBx:U23>-0.0265</PDBx:U23>
         <PDBx:U33>0.1983</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>575</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1455">
         <PDBx:U11>0.2898</PDBx:U11>
         <PDBx:U12>0.0232</PDBx:U12>
         <PDBx:U13>0.0088</PDBx:U13>
         <PDBx:U22>0.2720</PDBx:U22>
         <PDBx:U23>0.0109</PDBx:U23>
         <PDBx:U33>0.2274</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>575</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1456">
         <PDBx:U11>0.2815</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.2227</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.1965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>575</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1457">
         <PDBx:U11>0.2422</PDBx:U11>
         <PDBx:U12>-0.0203</PDBx:U12>
         <PDBx:U13>-0.0305</PDBx:U13>
         <PDBx:U22>0.2320</PDBx:U22>
         <PDBx:U23>0.0254</PDBx:U23>
         <PDBx:U33>0.2321</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>576</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1458">
         <PDBx:U11>0.2380</PDBx:U11>
         <PDBx:U12>-0.0040</PDBx:U12>
         <PDBx:U13>-0.0041</PDBx:U13>
         <PDBx:U22>0.2699</PDBx:U22>
         <PDBx:U23>0.0562</PDBx:U23>
         <PDBx:U33>0.1988</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>576</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1459">
         <PDBx:U11>0.2811</PDBx:U11>
         <PDBx:U12>-0.0114</PDBx:U12>
         <PDBx:U13>0.0036</PDBx:U13>
         <PDBx:U22>0.1893</PDBx:U22>
         <PDBx:U23>0.0076</PDBx:U23>
         <PDBx:U33>0.1897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>576</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1460">
         <PDBx:U11>0.2374</PDBx:U11>
         <PDBx:U12>0.0096</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.2098</PDBx:U22>
         <PDBx:U23>0.0072</PDBx:U23>
         <PDBx:U33>0.2112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>576</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1461">
         <PDBx:U11>0.2571</PDBx:U11>
         <PDBx:U12>-0.0196</PDBx:U12>
         <PDBx:U13>-0.0173</PDBx:U13>
         <PDBx:U22>0.3032</PDBx:U22>
         <PDBx:U23>0.0071</PDBx:U23>
         <PDBx:U33>0.3405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>576</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1462">
         <PDBx:U11>0.3461</PDBx:U11>
         <PDBx:U12>0.0300</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.3517</PDBx:U22>
         <PDBx:U23>0.0421</PDBx:U23>
         <PDBx:U33>0.4072</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>576</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1463">
         <PDBx:U11>0.2131</PDBx:U11>
         <PDBx:U12>-0.0077</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.1804</PDBx:U22>
         <PDBx:U23>0.0240</PDBx:U23>
         <PDBx:U33>0.2129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>577</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1464">
         <PDBx:U11>0.2224</PDBx:U11>
         <PDBx:U12>0.0098</PDBx:U12>
         <PDBx:U13>0.0074</PDBx:U13>
         <PDBx:U22>0.1685</PDBx:U22>
         <PDBx:U23>0.0023</PDBx:U23>
         <PDBx:U33>0.1673</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>577</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1465">
         <PDBx:U11>0.2044</PDBx:U11>
         <PDBx:U12>0.0052</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.1764</PDBx:U22>
         <PDBx:U23>-0.0085</PDBx:U23>
         <PDBx:U33>0.1645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>577</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1466">
         <PDBx:U11>0.2070</PDBx:U11>
         <PDBx:U12>-0.0054</PDBx:U12>
         <PDBx:U13>-0.0089</PDBx:U13>
         <PDBx:U22>0.1825</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.1875</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>577</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1467">
         <PDBx:U11>0.2399</PDBx:U11>
         <PDBx:U12>0.0539</PDBx:U12>
         <PDBx:U13>0.0054</PDBx:U13>
         <PDBx:U22>0.1949</PDBx:U22>
         <PDBx:U23>-0.0341</PDBx:U23>
         <PDBx:U33>0.2190</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>577</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1468">
         <PDBx:U11>0.2248</PDBx:U11>
         <PDBx:U12>0.0335</PDBx:U12>
         <PDBx:U13>-0.0063</PDBx:U13>
         <PDBx:U22>0.2366</PDBx:U22>
         <PDBx:U23>0.0123</PDBx:U23>
         <PDBx:U33>0.2046</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>577</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1469">
         <PDBx:U11>0.2186</PDBx:U11>
         <PDBx:U12>0.0205</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.2352</PDBx:U22>
         <PDBx:U23>-0.0161</PDBx:U23>
         <PDBx:U33>0.2102</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>577</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1470">
         <PDBx:U11>0.2137</PDBx:U11>
         <PDBx:U12>0.0229</PDBx:U12>
         <PDBx:U13>0.0162</PDBx:U13>
         <PDBx:U22>0.3194</PDBx:U22>
         <PDBx:U23>0.0106</PDBx:U23>
         <PDBx:U33>0.2429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>577</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1471">
         <PDBx:U11>0.2673</PDBx:U11>
         <PDBx:U12>0.0169</PDBx:U12>
         <PDBx:U13>-0.0143</PDBx:U13>
         <PDBx:U22>0.2597</PDBx:U22>
         <PDBx:U23>0.0100</PDBx:U23>
         <PDBx:U33>0.2626</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>577</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1472">
         <PDBx:U11>0.1885</PDBx:U11>
         <PDBx:U12>0.0137</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.1702</PDBx:U22>
         <PDBx:U23>-0.0145</PDBx:U23>
         <PDBx:U33>0.1872</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>578</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1473">
         <PDBx:U11>0.1902</PDBx:U11>
         <PDBx:U12>0.0316</PDBx:U12>
         <PDBx:U13>-0.0170</PDBx:U13>
         <PDBx:U22>0.1682</PDBx:U22>
         <PDBx:U23>-0.0158</PDBx:U23>
         <PDBx:U33>0.1825</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>578</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1474">
         <PDBx:U11>0.1587</PDBx:U11>
         <PDBx:U12>0.0327</PDBx:U12>
         <PDBx:U13>-0.0152</PDBx:U13>
         <PDBx:U22>0.1411</PDBx:U22>
         <PDBx:U23>0.0021</PDBx:U23>
         <PDBx:U33>0.1997</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>578</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1475">
         <PDBx:U11>0.2369</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>0.0224</PDBx:U13>
         <PDBx:U22>0.1815</PDBx:U22>
         <PDBx:U23>0.0045</PDBx:U23>
         <PDBx:U33>0.1876</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>578</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1476">
         <PDBx:U11>0.2206</PDBx:U11>
         <PDBx:U12>-0.0382</PDBx:U12>
         <PDBx:U13>-0.0569</PDBx:U13>
         <PDBx:U22>0.1934</PDBx:U22>
         <PDBx:U23>0.0112</PDBx:U23>
         <PDBx:U33>0.1989</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>578</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1477">
         <PDBx:U11>0.2461</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>0.0096</PDBx:U13>
         <PDBx:U22>0.2179</PDBx:U22>
         <PDBx:U23>0.0129</PDBx:U23>
         <PDBx:U33>0.1862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>578</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1478">
         <PDBx:U11>0.1897</PDBx:U11>
         <PDBx:U12>0.0074</PDBx:U12>
         <PDBx:U13>-0.0124</PDBx:U13>
         <PDBx:U22>0.1554</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.1965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>579</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1479">
         <PDBx:U11>0.1866</PDBx:U11>
         <PDBx:U12>-0.0301</PDBx:U12>
         <PDBx:U13>-0.0085</PDBx:U13>
         <PDBx:U22>0.1630</PDBx:U22>
         <PDBx:U23>0.0208</PDBx:U23>
         <PDBx:U33>0.1684</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>579</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1480">
         <PDBx:U11>0.1934</PDBx:U11>
         <PDBx:U12>0.0140</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.1726</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.1851</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>579</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1481">
         <PDBx:U11>0.1814</PDBx:U11>
         <PDBx:U12>-0.0070</PDBx:U12>
         <PDBx:U13>-0.0081</PDBx:U13>
         <PDBx:U22>0.1800</PDBx:U22>
         <PDBx:U23>-0.0061</PDBx:U23>
         <PDBx:U33>0.1745</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>579</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1482">
         <PDBx:U11>0.2075</PDBx:U11>
         <PDBx:U12>-0.0293</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1351</PDBx:U22>
         <PDBx:U23>0.0204</PDBx:U23>
         <PDBx:U33>0.2121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>579</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1483">
         <PDBx:U11>0.1839</PDBx:U11>
         <PDBx:U12>0.0093</PDBx:U12>
         <PDBx:U13>-0.0244</PDBx:U13>
         <PDBx:U22>0.1904</PDBx:U22>
         <PDBx:U23>0.0190</PDBx:U23>
         <PDBx:U33>0.1972</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>579</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1484">
         <PDBx:U11>0.2119</PDBx:U11>
         <PDBx:U12>0.0175</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.1899</PDBx:U22>
         <PDBx:U23>-0.0103</PDBx:U23>
         <PDBx:U33>0.1893</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>579</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1485">
         <PDBx:U11>0.2090</PDBx:U11>
         <PDBx:U12>0.0054</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.1993</PDBx:U22>
         <PDBx:U23>0.0100</PDBx:U23>
         <PDBx:U33>0.2157</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>579</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1486">
         <PDBx:U11>0.1681</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>0.0114</PDBx:U13>
         <PDBx:U22>0.1648</PDBx:U22>
         <PDBx:U23>-0.0061</PDBx:U23>
         <PDBx:U33>0.1773</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>580</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1487">
         <PDBx:U11>0.1694</PDBx:U11>
         <PDBx:U12>0.0039</PDBx:U12>
         <PDBx:U13>-0.0057</PDBx:U13>
         <PDBx:U22>0.1540</PDBx:U22>
         <PDBx:U23>-0.0103</PDBx:U23>
         <PDBx:U33>0.1653</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>580</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1488">
         <PDBx:U11>0.1806</PDBx:U11>
         <PDBx:U12>0.0103</PDBx:U12>
         <PDBx:U13>0.0085</PDBx:U13>
         <PDBx:U22>0.1478</PDBx:U22>
         <PDBx:U23>-0.0202</PDBx:U23>
         <PDBx:U33>0.1683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>580</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1489">
         <PDBx:U11>0.1916</PDBx:U11>
         <PDBx:U12>0.0041</PDBx:U12>
         <PDBx:U13>0.0123</PDBx:U13>
         <PDBx:U22>0.1520</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>580</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1490">
         <PDBx:U11>0.1769</PDBx:U11>
         <PDBx:U12>0.0117</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.1469</PDBx:U22>
         <PDBx:U23>0.0159</PDBx:U23>
         <PDBx:U33>0.1826</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>580</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1491">
         <PDBx:U11>0.1694</PDBx:U11>
         <PDBx:U12>0.0096</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.2104</PDBx:U22>
         <PDBx:U23>0.0140</PDBx:U23>
         <PDBx:U33>0.1833</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>580</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1492">
         <PDBx:U11>0.1891</PDBx:U11>
         <PDBx:U12>0.0273</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.1804</PDBx:U22>
         <PDBx:U23>0.0218</PDBx:U23>
         <PDBx:U33>0.1421</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>580</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1493">
         <PDBx:U11>0.1883</PDBx:U11>
         <PDBx:U12>0.0068</PDBx:U12>
         <PDBx:U13>-0.0096</PDBx:U13>
         <PDBx:U22>0.1888</PDBx:U22>
         <PDBx:U23>-0.0181</PDBx:U23>
         <PDBx:U33>0.2100</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>580</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1494">
         <PDBx:U11>0.1755</PDBx:U11>
         <PDBx:U12>-0.0119</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.1770</PDBx:U22>
         <PDBx:U23>-0.0176</PDBx:U23>
         <PDBx:U33>0.1876</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1495">
         <PDBx:U11>0.1531</PDBx:U11>
         <PDBx:U12>-0.0162</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.1862</PDBx:U22>
         <PDBx:U23>-0.0307</PDBx:U23>
         <PDBx:U33>0.1621</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1496">
         <PDBx:U11>0.1674</PDBx:U11>
         <PDBx:U12>0.0017</PDBx:U12>
         <PDBx:U13>0.0078</PDBx:U13>
         <PDBx:U22>0.1582</PDBx:U22>
         <PDBx:U23>0.0100</PDBx:U23>
         <PDBx:U33>0.1716</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1497">
         <PDBx:U11>0.1758</PDBx:U11>
         <PDBx:U12>0.0022</PDBx:U12>
         <PDBx:U13>0.0106</PDBx:U13>
         <PDBx:U22>0.1513</PDBx:U22>
         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.1736</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1498">
         <PDBx:U11>0.1744</PDBx:U11>
         <PDBx:U12>-0.0293</PDBx:U12>
         <PDBx:U13>-0.0054</PDBx:U13>
         <PDBx:U22>0.1859</PDBx:U22>
         <PDBx:U23>-0.0253</PDBx:U23>
         <PDBx:U33>0.1600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1499">
         <PDBx:U11>0.1838</PDBx:U11>
         <PDBx:U12>-0.0154</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.1685</PDBx:U22>
         <PDBx:U23>-0.0177</PDBx:U23>
         <PDBx:U33>0.2037</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1500">
         <PDBx:U11>0.1828</PDBx:U11>
         <PDBx:U12>-0.0176</PDBx:U12>
         <PDBx:U13>0.0143</PDBx:U13>
         <PDBx:U22>0.1881</PDBx:U22>
         <PDBx:U23>0.0090</PDBx:U23>
         <PDBx:U33>0.1619</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1501">
         <PDBx:U11>0.1967</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>0.0171</PDBx:U13>
         <PDBx:U22>0.1603</PDBx:U22>
         <PDBx:U23>-0.0100</PDBx:U23>
         <PDBx:U33>0.1890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1502">
         <PDBx:U11>0.1963</PDBx:U11>
         <PDBx:U12>-0.0154</PDBx:U12>
         <PDBx:U13>0.0109</PDBx:U13>
         <PDBx:U22>0.1595</PDBx:U22>
         <PDBx:U23>-0.0114</PDBx:U23>
         <PDBx:U33>0.1787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1503">
         <PDBx:U11>0.1841</PDBx:U11>
         <PDBx:U12>-0.0066</PDBx:U12>
         <PDBx:U13>0.0055</PDBx:U13>
         <PDBx:U22>0.1461</PDBx:U22>
         <PDBx:U23>0.0020</PDBx:U23>
         <PDBx:U33>0.1674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1504">
         <PDBx:U11>0.1986</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>-0.0244</PDBx:U13>
         <PDBx:U22>0.1618</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.1665</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1505">
         <PDBx:U11>0.2161</PDBx:U11>
         <PDBx:U12>-0.0219</PDBx:U12>
         <PDBx:U13>0.0047</PDBx:U13>
         <PDBx:U22>0.1418</PDBx:U22>
         <PDBx:U23>0.0077</PDBx:U23>
         <PDBx:U33>0.1961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1506">
         <PDBx:U11>0.2278</PDBx:U11>
         <PDBx:U12>-0.0156</PDBx:U12>
         <PDBx:U13>0.0169</PDBx:U13>
         <PDBx:U22>0.1788</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1831</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1507">
         <PDBx:U11>0.2158</PDBx:U11>
         <PDBx:U12>0.0167</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.2223</PDBx:U22>
         <PDBx:U23>-0.0131</PDBx:U23>
         <PDBx:U33>0.1836</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>581</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1508">
         <PDBx:U11>0.1597</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>0.0036</PDBx:U13>
         <PDBx:U22>0.1333</PDBx:U22>
         <PDBx:U23>-0.0125</PDBx:U23>
         <PDBx:U33>0.1753</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>582</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1509">
         <PDBx:U11>0.1812</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.1507</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.1671</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>582</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1510">
         <PDBx:U11>0.1695</PDBx:U11>
         <PDBx:U12>0.0173</PDBx:U12>
         <PDBx:U13>0.0117</PDBx:U13>
         <PDBx:U22>0.1913</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.1636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>582</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1511">
         <PDBx:U11>0.1794</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>0.0046</PDBx:U13>
         <PDBx:U22>0.1584</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.1669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>582</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1512">
         <PDBx:U11>0.2075</PDBx:U11>
         <PDBx:U12>0.0288</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.1512</PDBx:U22>
         <PDBx:U23>0.0035</PDBx:U23>
         <PDBx:U33>0.1789</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>582</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1513">
         <PDBx:U11>0.1565</PDBx:U11>
         <PDBx:U12>0.0084</PDBx:U12>
         <PDBx:U13>-0.0208</PDBx:U13>
         <PDBx:U22>0.1586</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.1798</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>583</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1514">
         <PDBx:U11>0.1600</PDBx:U11>
         <PDBx:U12>-0.0123</PDBx:U12>
         <PDBx:U13>-0.0078</PDBx:U13>
         <PDBx:U22>0.1767</PDBx:U22>
         <PDBx:U23>0.0214</PDBx:U23>
         <PDBx:U33>0.1557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>583</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1515">
         <PDBx:U11>0.2316</PDBx:U11>
         <PDBx:U12>-0.0089</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.1573</PDBx:U22>
         <PDBx:U23>0.0066</PDBx:U23>
         <PDBx:U33>0.1640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>583</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1516">
         <PDBx:U11>0.1775</PDBx:U11>
         <PDBx:U12>0.0088</PDBx:U12>
         <PDBx:U13>0.0109</PDBx:U13>
         <PDBx:U22>0.1577</PDBx:U22>
         <PDBx:U23>-0.0131</PDBx:U23>
         <PDBx:U33>0.1746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>583</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1517">
         <PDBx:U11>0.1487</PDBx:U11>
         <PDBx:U12>0.0042</PDBx:U12>
         <PDBx:U13>-0.0251</PDBx:U13>
         <PDBx:U22>0.1674</PDBx:U22>
         <PDBx:U23>0.0040</PDBx:U23>
         <PDBx:U33>0.1620</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>583</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1518">
         <PDBx:U11>0.1661</PDBx:U11>
         <PDBx:U12>0.0204</PDBx:U12>
         <PDBx:U13>-0.0140</PDBx:U13>
         <PDBx:U22>0.1463</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.1474</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>583</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1519">
         <PDBx:U11>0.1865</PDBx:U11>
         <PDBx:U12>-0.0072</PDBx:U12>
         <PDBx:U13>-0.0149</PDBx:U13>
         <PDBx:U22>0.1652</PDBx:U22>
         <PDBx:U23>-0.0207</PDBx:U23>
         <PDBx:U33>0.1576</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>583</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1520">
         <PDBx:U11>0.1872</PDBx:U11>
         <PDBx:U12>0.0354</PDBx:U12>
         <PDBx:U13>-0.0205</PDBx:U13>
         <PDBx:U22>0.1633</PDBx:U22>
         <PDBx:U23>0.0096</PDBx:U23>
         <PDBx:U33>0.2138</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>583</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1521">
         <PDBx:U11>0.1956</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>-0.0360</PDBx:U13>
         <PDBx:U22>0.1945</PDBx:U22>
         <PDBx:U23>0.0113</PDBx:U23>
         <PDBx:U33>0.1752</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>583</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1522">
         <PDBx:U11>0.2470</PDBx:U11>
         <PDBx:U12>0.0164</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.2022</PDBx:U22>
         <PDBx:U23>-0.0110</PDBx:U23>
         <PDBx:U33>0.2009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>583</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1523">
         <PDBx:U11>0.1841</PDBx:U11>
         <PDBx:U12>0.0006</PDBx:U12>
         <PDBx:U13>0.0083</PDBx:U13>
         <PDBx:U22>0.1571</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.1757</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>583</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1524">
         <PDBx:U11>0.1624</PDBx:U11>
         <PDBx:U12>0.0057</PDBx:U12>
         <PDBx:U13>-0.0030</PDBx:U13>
         <PDBx:U22>0.1388</PDBx:U22>
         <PDBx:U23>0.0163</PDBx:U23>
         <PDBx:U33>0.1753</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>584</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1525">
         <PDBx:U11>0.2250</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>0.0005</PDBx:U13>
         <PDBx:U22>0.1921</PDBx:U22>
         <PDBx:U23>0.0230</PDBx:U23>
         <PDBx:U33>0.1687</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>584</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1526">
         <PDBx:U11>0.2048</PDBx:U11>
         <PDBx:U12>0.0124</PDBx:U12>
         <PDBx:U13>-0.0053</PDBx:U13>
         <PDBx:U22>0.1448</PDBx:U22>
         <PDBx:U23>0.0108</PDBx:U23>
         <PDBx:U33>0.1744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>584</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1527">
         <PDBx:U11>0.1937</PDBx:U11>
         <PDBx:U12>0.0120</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.1437</PDBx:U22>
         <PDBx:U23>0.0018</PDBx:U23>
         <PDBx:U33>0.1666</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>584</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1528">
         <PDBx:U11>0.1524</PDBx:U11>
         <PDBx:U12>-0.0019</PDBx:U12>
         <PDBx:U13>-0.0118</PDBx:U13>
         <PDBx:U22>0.1537</PDBx:U22>
         <PDBx:U23>-0.0241</PDBx:U23>
         <PDBx:U33>0.1795</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>585</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1529">
         <PDBx:U11>0.1595</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>-0.0145</PDBx:U13>
         <PDBx:U22>0.1750</PDBx:U22>
         <PDBx:U23>-0.0286</PDBx:U23>
         <PDBx:U33>0.1551</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>585</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1530">
         <PDBx:U11>0.1599</PDBx:U11>
         <PDBx:U12>0.0065</PDBx:U12>
         <PDBx:U13>-0.0117</PDBx:U13>
         <PDBx:U22>0.1427</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.1663</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>585</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1531">
         <PDBx:U11>0.1966</PDBx:U11>
         <PDBx:U12>-0.0021</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.1534</PDBx:U22>
         <PDBx:U23>-0.0078</PDBx:U23>
         <PDBx:U33>0.1795</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>585</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1532">
         <PDBx:U11>0.1593</PDBx:U11>
         <PDBx:U12>0.0173</PDBx:U12>
         <PDBx:U13>-0.0150</PDBx:U13>
         <PDBx:U22>0.1620</PDBx:U22>
         <PDBx:U23>-0.0348</PDBx:U23>
         <PDBx:U33>0.1620</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>585</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1533">
         <PDBx:U11>0.1724</PDBx:U11>
         <PDBx:U12>0.0282</PDBx:U12>
         <PDBx:U13>0.0246</PDBx:U13>
         <PDBx:U22>0.1578</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.1895</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>585</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1534">
         <PDBx:U11>0.1880</PDBx:U11>
         <PDBx:U12>-0.0147</PDBx:U12>
         <PDBx:U13>-0.0109</PDBx:U13>
         <PDBx:U22>0.1621</PDBx:U22>
         <PDBx:U23>-0.0416</PDBx:U23>
         <PDBx:U33>0.1744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>585</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1535">
         <PDBx:U11>0.1818</PDBx:U11>
         <PDBx:U12>-0.0082</PDBx:U12>
         <PDBx:U13>-0.0079</PDBx:U13>
         <PDBx:U22>0.1548</PDBx:U22>
         <PDBx:U23>-0.0287</PDBx:U23>
         <PDBx:U33>0.1743</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>586</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1536">
         <PDBx:U11>0.1811</PDBx:U11>
         <PDBx:U12>-0.0083</PDBx:U12>
         <PDBx:U13>-0.0126</PDBx:U13>
         <PDBx:U22>0.1470</PDBx:U22>
         <PDBx:U23>-0.0105</PDBx:U23>
         <PDBx:U33>0.1553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>586</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1537">
         <PDBx:U11>0.1832</PDBx:U11>
         <PDBx:U12>0.0066</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.1742</PDBx:U22>
         <PDBx:U23>0.0130</PDBx:U23>
         <PDBx:U33>0.1725</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>586</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1538">
         <PDBx:U11>0.1852</PDBx:U11>
         <PDBx:U12>0.0027</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.1377</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.1814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>586</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1539">
         <PDBx:U11>0.1799</PDBx:U11>
         <PDBx:U12>-0.0177</PDBx:U12>
         <PDBx:U13>0.0157</PDBx:U13>
         <PDBx:U22>0.1454</PDBx:U22>
         <PDBx:U23>-0.0120</PDBx:U23>
         <PDBx:U33>0.1712</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>586</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1540">
         <PDBx:U11>0.2669</PDBx:U11>
         <PDBx:U12>-0.0659</PDBx:U12>
         <PDBx:U13>0.0809</PDBx:U13>
         <PDBx:U22>0.1628</PDBx:U22>
         <PDBx:U23>-0.0378</PDBx:U23>
         <PDBx:U33>0.2689</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>586</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1541">
         <PDBx:U11>0.3336</PDBx:U11>
         <PDBx:U12>0.1021</PDBx:U12>
         <PDBx:U13>0.0448</PDBx:U13>
         <PDBx:U22>0.2910</PDBx:U22>
         <PDBx:U23>0.0750</PDBx:U23>
         <PDBx:U33>0.2987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>586</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1542">
         <PDBx:U11>0.3334</PDBx:U11>
         <PDBx:U12>-0.0536</PDBx:U12>
         <PDBx:U13>0.0844</PDBx:U13>
         <PDBx:U22>0.2015</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.2803</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>586</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1543">
         <PDBx:U11>0.1652</PDBx:U11>
         <PDBx:U12>-0.0219</PDBx:U12>
         <PDBx:U13>-0.0141</PDBx:U13>
         <PDBx:U22>0.1309</PDBx:U22>
         <PDBx:U23>-0.0062</PDBx:U23>
         <PDBx:U33>0.1938</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>587</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1544">
         <PDBx:U11>0.2021</PDBx:U11>
         <PDBx:U12>0.0252</PDBx:U12>
         <PDBx:U13>0.0074</PDBx:U13>
         <PDBx:U22>0.1524</PDBx:U22>
         <PDBx:U23>-0.0120</PDBx:U23>
         <PDBx:U33>0.1840</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>587</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1545">
         <PDBx:U11>0.1790</PDBx:U11>
         <PDBx:U12>0.0122</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.1748</PDBx:U22>
         <PDBx:U23>-0.0081</PDBx:U23>
         <PDBx:U33>0.1682</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>587</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1546">
         <PDBx:U11>0.1986</PDBx:U11>
         <PDBx:U12>0.0007</PDBx:U12>
         <PDBx:U13>-0.0143</PDBx:U13>
         <PDBx:U22>0.1735</PDBx:U22>
         <PDBx:U23>-0.0096</PDBx:U23>
         <PDBx:U33>0.1510</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>587</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1547">
         <PDBx:U11>0.1440</PDBx:U11>
         <PDBx:U12>0.0120</PDBx:U12>
         <PDBx:U13>0.0142</PDBx:U13>
         <PDBx:U22>0.1752</PDBx:U22>
         <PDBx:U23>0.0249</PDBx:U23>
         <PDBx:U33>0.2985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>587</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1548">
         <PDBx:U11>0.1454</PDBx:U11>
         <PDBx:U12>0.0180</PDBx:U12>
         <PDBx:U13>-0.0097</PDBx:U13>
         <PDBx:U22>0.2559</PDBx:U22>
         <PDBx:U23>0.0465</PDBx:U23>
         <PDBx:U33>0.2257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>587</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1549">
         <PDBx:U11>0.2122</PDBx:U11>
         <PDBx:U12>0.0159</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.1996</PDBx:U22>
         <PDBx:U23>0.0133</PDBx:U23>
         <PDBx:U33>0.2053</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>587</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1550">
         <PDBx:U11>0.2166</PDBx:U11>
         <PDBx:U12>0.0623</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.2117</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.2006</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>587</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1551">
         <PDBx:U11>0.1852</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>0.0099</PDBx:U13>
         <PDBx:U22>0.1273</PDBx:U22>
         <PDBx:U23>0.0141</PDBx:U23>
         <PDBx:U33>0.1963</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>588</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1552">
         <PDBx:U11>0.1848</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.1569</PDBx:U22>
         <PDBx:U23>-0.0183</PDBx:U23>
         <PDBx:U33>0.1777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>588</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1553">
         <PDBx:U11>0.1568</PDBx:U11>
         <PDBx:U12>-0.0011</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.1600</PDBx:U22>
         <PDBx:U23>0.0159</PDBx:U23>
         <PDBx:U33>0.1670</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>588</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1554">
         <PDBx:U11>0.2188</PDBx:U11>
         <PDBx:U12>-0.0080</PDBx:U12>
         <PDBx:U13>0.0090</PDBx:U13>
         <PDBx:U22>0.1700</PDBx:U22>
         <PDBx:U23>0.0097</PDBx:U23>
         <PDBx:U33>0.1672</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>588</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1555">
         <PDBx:U11>0.1690</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>-0.0132</PDBx:U13>
         <PDBx:U22>0.1534</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.1775</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>588</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1556">
         <PDBx:U11>0.1781</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>0.0172</PDBx:U13>
         <PDBx:U22>0.1626</PDBx:U22>
         <PDBx:U23>0.0058</PDBx:U23>
         <PDBx:U33>0.1647</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>588</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1557">
         <PDBx:U11>0.2188</PDBx:U11>
         <PDBx:U12>-0.0274</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.1483</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.2147</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>588</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1558">
         <PDBx:U11>0.1783</PDBx:U11>
         <PDBx:U12>0.0072</PDBx:U12>
         <PDBx:U13>0.0134</PDBx:U13>
         <PDBx:U22>0.1430</PDBx:U22>
         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.1824</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>588</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1559">
         <PDBx:U11>0.1844</PDBx:U11>
         <PDBx:U12>0.0152</PDBx:U12>
         <PDBx:U13>-0.0143</PDBx:U13>
         <PDBx:U22>0.1603</PDBx:U22>
         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.1830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>588</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1560">
         <PDBx:U11>0.1906</PDBx:U11>
         <PDBx:U12>0.0093</PDBx:U12>
         <PDBx:U13>-0.0043</PDBx:U13>
         <PDBx:U22>0.1692</PDBx:U22>
         <PDBx:U23>0.0037</PDBx:U23>
         <PDBx:U33>0.1809</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>588</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>588</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>588</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>589</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>589</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>589</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0028</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>589</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0006</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>589</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>589</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0090</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>589</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0080</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>589</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0033</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>589</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0016</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>590</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.0086</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>590</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>590</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1577">
         <PDBx:U11>0.1861</PDBx:U11>
         <PDBx:U12>0.0079</PDBx:U12>
         <PDBx:U13>0.0038</PDBx:U13>
         <PDBx:U22>0.1717</PDBx:U22>
         <PDBx:U23>-0.0027</PDBx:U23>
         <PDBx:U33>0.1493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>590</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1578">
         <PDBx:U11>0.1799</PDBx:U11>
         <PDBx:U12>-0.0166</PDBx:U12>
         <PDBx:U13>-0.0237</PDBx:U13>
         <PDBx:U22>0.1694</PDBx:U22>
         <PDBx:U23>0.0085</PDBx:U23>
         <PDBx:U33>0.1570</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>590</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1579">
         <PDBx:U11>0.1838</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.1798</PDBx:U22>
         <PDBx:U23>0.0235</PDBx:U23>
         <PDBx:U33>0.1788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>590</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1580">
         <PDBx:U11>0.1870</PDBx:U11>
         <PDBx:U12>0.0118</PDBx:U12>
         <PDBx:U13>-0.0281</PDBx:U13>
         <PDBx:U22>0.1847</PDBx:U22>
         <PDBx:U23>-0.0280</PDBx:U23>
         <PDBx:U33>0.1678</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>590</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1581">
         <PDBx:U11>0.2119</PDBx:U11>
         <PDBx:U12>-0.0222</PDBx:U12>
         <PDBx:U13>0.0475</PDBx:U13>
         <PDBx:U22>0.1958</PDBx:U22>
         <PDBx:U23>0.0003</PDBx:U23>
         <PDBx:U33>0.2001</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>590</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1582">
         <PDBx:U11>0.1752</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>-0.0116</PDBx:U13>
         <PDBx:U22>0.1540</PDBx:U22>
         <PDBx:U23>0.0181</PDBx:U23>
         <PDBx:U33>0.1634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>591</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1583">
         <PDBx:U11>0.1763</PDBx:U11>
         <PDBx:U12>0.0322</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.1226</PDBx:U22>
         <PDBx:U23>0.0132</PDBx:U23>
         <PDBx:U33>0.1756</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>591</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1584">
         <PDBx:U11>0.1836</PDBx:U11>
         <PDBx:U12>0.0071</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1573</PDBx:U22>
         <PDBx:U23>0.0195</PDBx:U23>
         <PDBx:U33>0.1807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>591</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1585">
         <PDBx:U11>0.1957</PDBx:U11>
         <PDBx:U12>0.0022</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.1926</PDBx:U22>
         <PDBx:U23>0.0185</PDBx:U23>
         <PDBx:U33>0.1635</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>591</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1586">
         <PDBx:U11>0.1848</PDBx:U11>
         <PDBx:U12>0.0400</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>0.1542</PDBx:U22>
         <PDBx:U23>-0.0124</PDBx:U23>
         <PDBx:U33>0.1919</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>591</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1587">
         <PDBx:U11>0.1825</PDBx:U11>
         <PDBx:U12>-0.0079</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>0.1559</PDBx:U22>
         <PDBx:U23>0.0154</PDBx:U23>
         <PDBx:U33>0.1637</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>591</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1588">
         <PDBx:U11>0.1692</PDBx:U11>
         <PDBx:U12>-0.0092</PDBx:U12>
         <PDBx:U13>0.0238</PDBx:U13>
         <PDBx:U22>0.2136</PDBx:U22>
         <PDBx:U23>0.0063</PDBx:U23>
         <PDBx:U33>0.2231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>591</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1589">
         <PDBx:U11>0.2133</PDBx:U11>
         <PDBx:U12>0.0233</PDBx:U12>
         <PDBx:U13>-0.0133</PDBx:U13>
         <PDBx:U22>0.1722</PDBx:U22>
         <PDBx:U23>0.0061</PDBx:U23>
         <PDBx:U33>0.1659</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>591</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1590">
         <PDBx:U11>0.1740</PDBx:U11>
         <PDBx:U12>0.0181</PDBx:U12>
         <PDBx:U13>-0.0040</PDBx:U13>
         <PDBx:U22>0.1623</PDBx:U22>
         <PDBx:U23>0.0240</PDBx:U23>
         <PDBx:U33>0.1967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>591</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1591">
         <PDBx:U11>0.2111</PDBx:U11>
         <PDBx:U12>-0.0011</PDBx:U12>
         <PDBx:U13>0.0258</PDBx:U13>
         <PDBx:U22>0.1909</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.2052</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>591</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1592">
         <PDBx:U11>0.1826</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.1920</PDBx:U22>
         <PDBx:U23>0.0142</PDBx:U23>
         <PDBx:U33>0.1738</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>591</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1593">
         <PDBx:U11>0.2200</PDBx:U11>
         <PDBx:U12>-0.0086</PDBx:U12>
         <PDBx:U13>-0.0259</PDBx:U13>
         <PDBx:U22>0.2284</PDBx:U22>
         <PDBx:U23>-0.0093</PDBx:U23>
         <PDBx:U33>0.2590</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>591</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1594">
         <PDBx:U11>0.1822</PDBx:U11>
         <PDBx:U12>0.0218</PDBx:U12>
         <PDBx:U13>-0.0044</PDBx:U13>
         <PDBx:U22>0.1557</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.1868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>592</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1595">
         <PDBx:U11>0.1945</PDBx:U11>
         <PDBx:U12>0.0042</PDBx:U12>
         <PDBx:U13>-0.0145</PDBx:U13>
         <PDBx:U22>0.1724</PDBx:U22>
         <PDBx:U23>0.0020</PDBx:U23>
         <PDBx:U33>0.1708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>592</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1596">
         <PDBx:U11>0.1971</PDBx:U11>
         <PDBx:U12>0.0077</PDBx:U12>
         <PDBx:U13>-0.0194</PDBx:U13>
         <PDBx:U22>0.1767</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.1765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>592</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1597">
         <PDBx:U11>0.2126</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>0.0192</PDBx:U13>
         <PDBx:U22>0.1857</PDBx:U22>
         <PDBx:U23>-0.0347</PDBx:U23>
         <PDBx:U33>0.2391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>592</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1598">
         <PDBx:U11>0.1721</PDBx:U11>
         <PDBx:U12>0.0005</PDBx:U12>
         <PDBx:U13>-0.0064</PDBx:U13>
         <PDBx:U22>0.2199</PDBx:U22>
         <PDBx:U23>-0.0946</PDBx:U23>
         <PDBx:U33>0.2191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>592</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1599">
         <PDBx:U11>0.2642</PDBx:U11>
         <PDBx:U12>0.0306</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.1987</PDBx:U22>
         <PDBx:U23>0.0070</PDBx:U23>
         <PDBx:U33>0.2147</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>592</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1600">
         <PDBx:U11>0.1967</PDBx:U11>
         <PDBx:U12>0.0043</PDBx:U12>
         <PDBx:U13>-0.0077</PDBx:U13>
         <PDBx:U22>0.1646</PDBx:U22>
         <PDBx:U23>-0.0096</PDBx:U23>
         <PDBx:U33>0.1935</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>593</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1601">
         <PDBx:U11>0.2275</PDBx:U11>
         <PDBx:U12>0.0288</PDBx:U12>
         <PDBx:U13>0.0125</PDBx:U13>
         <PDBx:U22>0.1902</PDBx:U22>
         <PDBx:U23>0.0062</PDBx:U23>
         <PDBx:U33>0.1807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>593</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1602">
         <PDBx:U11>0.1846</PDBx:U11>
         <PDBx:U12>-0.0297</PDBx:U12>
         <PDBx:U13>0.0193</PDBx:U13>
         <PDBx:U22>0.1981</PDBx:U22>
         <PDBx:U23>0.0065</PDBx:U23>
         <PDBx:U33>0.1765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>593</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1603">
         <PDBx:U11>0.2239</PDBx:U11>
         <PDBx:U12>0.0212</PDBx:U12>
         <PDBx:U13>0.0104</PDBx:U13>
         <PDBx:U22>0.2116</PDBx:U22>
         <PDBx:U23>-0.0133</PDBx:U23>
         <PDBx:U33>0.2045</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>593</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1604">
         <PDBx:U11>0.1980</PDBx:U11>
         <PDBx:U12>0.0124</PDBx:U12>
         <PDBx:U13>-0.0075</PDBx:U13>
         <PDBx:U22>0.2050</PDBx:U22>
         <PDBx:U23>-0.0168</PDBx:U23>
         <PDBx:U33>0.1652</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>593</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1605">
         <PDBx:U11>0.2042</PDBx:U11>
         <PDBx:U12>-0.0113</PDBx:U12>
         <PDBx:U13>0.0187</PDBx:U13>
         <PDBx:U22>0.2048</PDBx:U22>
         <PDBx:U23>0.0222</PDBx:U23>
         <PDBx:U33>0.1763</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>593</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1606">
         <PDBx:U11>0.2974</PDBx:U11>
         <PDBx:U12>0.0136</PDBx:U12>
         <PDBx:U13>0.0412</PDBx:U13>
         <PDBx:U22>0.2401</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.1643</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>593</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1607">
         <PDBx:U11>0.1925</PDBx:U11>
         <PDBx:U12>-0.0326</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.2244</PDBx:U22>
         <PDBx:U23>-0.0191</PDBx:U23>
         <PDBx:U33>0.2270</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>593</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1608">
         <PDBx:U11>0.2195</PDBx:U11>
         <PDBx:U12>0.0049</PDBx:U12>
         <PDBx:U13>-0.0157</PDBx:U13>
         <PDBx:U22>0.1775</PDBx:U22>
         <PDBx:U23>-0.0184</PDBx:U23>
         <PDBx:U33>0.1736</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>594</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1609">
         <PDBx:U11>0.1836</PDBx:U11>
         <PDBx:U12>0.0004</PDBx:U12>
         <PDBx:U13>-0.0064</PDBx:U13>
         <PDBx:U22>0.1503</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.2127</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>594</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1610">
         <PDBx:U11>0.1720</PDBx:U11>
         <PDBx:U12>0.0132</PDBx:U12>
         <PDBx:U13>0.0134</PDBx:U13>
         <PDBx:U22>0.1854</PDBx:U22>
         <PDBx:U23>-0.0206</PDBx:U23>
         <PDBx:U33>0.1934</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>594</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1611">
         <PDBx:U11>0.2034</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>-0.0278</PDBx:U13>
         <PDBx:U22>0.2160</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.2238</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>594</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1612">
         <PDBx:U11>0.2091</PDBx:U11>
         <PDBx:U12>0.0017</PDBx:U12>
         <PDBx:U13>-0.0157</PDBx:U13>
         <PDBx:U22>0.1839</PDBx:U22>
         <PDBx:U23>-0.0077</PDBx:U23>
         <PDBx:U33>0.1916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>595</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1613">
         <PDBx:U11>0.1958</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>-0.0152</PDBx:U13>
         <PDBx:U22>0.2070</PDBx:U22>
         <PDBx:U23>0.0108</PDBx:U23>
         <PDBx:U33>0.2030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>595</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1614">
         <PDBx:U11>0.1880</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>0.0093</PDBx:U13>
         <PDBx:U22>0.1998</PDBx:U22>
         <PDBx:U23>0.0285</PDBx:U23>
         <PDBx:U33>0.2000</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>595</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1615">
         <PDBx:U11>0.2080</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.1730</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.1746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>595</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1616">
         <PDBx:U11>0.2708</PDBx:U11>
         <PDBx:U12>0.0096</PDBx:U12>
         <PDBx:U13>-0.0303</PDBx:U13>
         <PDBx:U22>0.2051</PDBx:U22>
         <PDBx:U23>0.0186</PDBx:U23>
         <PDBx:U33>0.2079</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>595</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1617">
         <PDBx:U11>0.2884</PDBx:U11>
         <PDBx:U12>0.0063</PDBx:U12>
         <PDBx:U13>0.0194</PDBx:U13>
         <PDBx:U22>0.2734</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.2381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>595</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1618">
         <PDBx:U11>0.3298</PDBx:U11>
         <PDBx:U12>-0.0249</PDBx:U12>
         <PDBx:U13>-0.0597</PDBx:U13>
         <PDBx:U22>0.3143</PDBx:U22>
         <PDBx:U23>0.0997</PDBx:U23>
         <PDBx:U33>0.3744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>595</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1619">
         <PDBx:U11>0.6035</PDBx:U11>
         <PDBx:U12>-0.0921</PDBx:U12>
         <PDBx:U13>-0.0703</PDBx:U13>
         <PDBx:U22>0.4057</PDBx:U22>
         <PDBx:U23>0.1453</PDBx:U23>
         <PDBx:U33>0.4058</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>595</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1620">
         <PDBx:U11>0.7911</PDBx:U11>
         <PDBx:U12>0.0099</PDBx:U12>
         <PDBx:U13>-0.0495</PDBx:U13>
         <PDBx:U22>0.5041</PDBx:U22>
         <PDBx:U23>0.0111</PDBx:U23>
         <PDBx:U33>0.7488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>595</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1621">
         <PDBx:U11>0.2068</PDBx:U11>
         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>-0.0346</PDBx:U13>
         <PDBx:U22>0.1883</PDBx:U22>
         <PDBx:U23>-0.0097</PDBx:U23>
         <PDBx:U33>0.1744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>596</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1622">
         <PDBx:U11>0.2313</PDBx:U11>
         <PDBx:U12>-0.0080</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>0.1590</PDBx:U22>
         <PDBx:U23>0.0158</PDBx:U23>
         <PDBx:U33>0.1660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>596</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1623">
         <PDBx:U11>0.2473</PDBx:U11>
         <PDBx:U12>0.0325</PDBx:U12>
         <PDBx:U13>0.0395</PDBx:U13>
         <PDBx:U22>0.2328</PDBx:U22>
         <PDBx:U23>0.0195</PDBx:U23>
         <PDBx:U33>0.1864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>596</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1624">
         <PDBx:U11>0.2016</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>0.0191</PDBx:U13>
         <PDBx:U22>0.1758</PDBx:U22>
         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.2283</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>596</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1625">
         <PDBx:U11>0.2162</PDBx:U11>
         <PDBx:U12>0.0099</PDBx:U12>
         <PDBx:U13>0.0193</PDBx:U13>
         <PDBx:U22>0.2031</PDBx:U22>
         <PDBx:U23>-0.0620</PDBx:U23>
         <PDBx:U33>0.2461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>596</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1626">
         <PDBx:U11>0.2809</PDBx:U11>
         <PDBx:U12>0.0893</PDBx:U12>
         <PDBx:U13>-0.0894</PDBx:U13>
         <PDBx:U22>0.4938</PDBx:U22>
         <PDBx:U23>-0.3532</PDBx:U23>
         <PDBx:U33>0.3315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>596</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1627">
         <PDBx:U11>0.3738</PDBx:U11>
         <PDBx:U12>0.0099</PDBx:U12>
         <PDBx:U13>-0.0129</PDBx:U13>
         <PDBx:U22>0.4670</PDBx:U22>
         <PDBx:U23>-0.0363</PDBx:U23>
         <PDBx:U33>0.3953</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>596</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1628">
         <PDBx:U11>0.6664</PDBx:U11>
         <PDBx:U12>0.0088</PDBx:U12>
         <PDBx:U13>-0.0732</PDBx:U13>
         <PDBx:U22>0.2660</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.5354</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>596</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1629">
         <PDBx:U11>0.1718</PDBx:U11>
         <PDBx:U12>0.0048</PDBx:U12>
         <PDBx:U13>-0.0080</PDBx:U13>
         <PDBx:U22>0.1590</PDBx:U22>
         <PDBx:U23>0.0004</PDBx:U23>
         <PDBx:U33>0.1730</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>597</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1630">
         <PDBx:U11>0.1880</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.1555</PDBx:U22>
         <PDBx:U23>-0.0128</PDBx:U23>
         <PDBx:U33>0.1870</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>597</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1631">
         <PDBx:U11>0.1700</PDBx:U11>
         <PDBx:U12>0.0057</PDBx:U12>
         <PDBx:U13>-0.0055</PDBx:U13>
         <PDBx:U22>0.1735</PDBx:U22>
         <PDBx:U23>0.0092</PDBx:U23>
         <PDBx:U33>0.2119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>597</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1632">
         <PDBx:U11>0.1573</PDBx:U11>
         <PDBx:U12>-0.0016</PDBx:U12>
         <PDBx:U13>-0.0072</PDBx:U13>
         <PDBx:U22>0.1828</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.1982</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>597</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1633">
         <PDBx:U11>0.2062</PDBx:U11>
         <PDBx:U12>-0.0180</PDBx:U12>
         <PDBx:U13>0.0237</PDBx:U13>
         <PDBx:U22>0.2049</PDBx:U22>
         <PDBx:U23>-0.0087</PDBx:U23>
         <PDBx:U33>0.1985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>597</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1634">
         <PDBx:U11>0.2035</PDBx:U11>
         <PDBx:U12>0.0196</PDBx:U12>
         <PDBx:U13>0.0187</PDBx:U13>
         <PDBx:U22>0.1943</PDBx:U22>
         <PDBx:U23>-0.0184</PDBx:U23>
         <PDBx:U33>0.2254</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>597</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1635">
         <PDBx:U11>0.1559</PDBx:U11>
         <PDBx:U12>-0.0096</PDBx:U12>
         <PDBx:U13>0.0156</PDBx:U13>
         <PDBx:U22>0.1852</PDBx:U22>
         <PDBx:U23>0.0094</PDBx:U23>
         <PDBx:U33>0.1858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>597</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1636">
         <PDBx:U11>0.1732</PDBx:U11>
         <PDBx:U12>-0.0178</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.1651</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.2161</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>598</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1637">
         <PDBx:U11>0.1713</PDBx:U11>
         <PDBx:U12>-0.0172</PDBx:U12>
         <PDBx:U13>0.0093</PDBx:U13>
         <PDBx:U22>0.1878</PDBx:U22>
         <PDBx:U23>-0.0184</PDBx:U23>
         <PDBx:U33>0.1987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>598</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1638">
         <PDBx:U11>0.1807</PDBx:U11>
         <PDBx:U12>0.0313</PDBx:U12>
         <PDBx:U13>-0.0011</PDBx:U13>
         <PDBx:U22>0.2174</PDBx:U22>
         <PDBx:U23>-0.0154</PDBx:U23>
         <PDBx:U33>0.2087</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>598</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1639">
         <PDBx:U11>0.1840</PDBx:U11>
         <PDBx:U12>-0.0337</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.1921</PDBx:U22>
         <PDBx:U23>0.0255</PDBx:U23>
         <PDBx:U33>0.2009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>598</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1640">
         <PDBx:U11>0.1636</PDBx:U11>
         <PDBx:U12>0.0223</PDBx:U12>
         <PDBx:U13>0.0117</PDBx:U13>
         <PDBx:U22>0.1741</PDBx:U22>
         <PDBx:U23>-0.0199</PDBx:U23>
         <PDBx:U33>0.1870</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>598</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1641">
         <PDBx:U11>0.1670</PDBx:U11>
         <PDBx:U12>-0.0070</PDBx:U12>
         <PDBx:U13>0.0158</PDBx:U13>
         <PDBx:U22>0.1692</PDBx:U22>
         <PDBx:U23>-0.0127</PDBx:U23>
         <PDBx:U33>0.1676</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>598</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1642">
         <PDBx:U11>0.1829</PDBx:U11>
         <PDBx:U12>-0.0239</PDBx:U12>
         <PDBx:U13>-0.0023</PDBx:U13>
         <PDBx:U22>0.1902</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.1753</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>598</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1643">
         <PDBx:U11>0.2182</PDBx:U11>
         <PDBx:U12>0.0250</PDBx:U12>
         <PDBx:U13>0.0176</PDBx:U13>
         <PDBx:U22>0.1884</PDBx:U22>
         <PDBx:U23>-0.0254</PDBx:U23>
         <PDBx:U33>0.1800</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>598</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1644">
         <PDBx:U11>0.2066</PDBx:U11>
         <PDBx:U12>0.0175</PDBx:U12>
         <PDBx:U13>-0.0130</PDBx:U13>
         <PDBx:U22>0.1877</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1887</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>598</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1645">
         <PDBx:U11>0.1958</PDBx:U11>
         <PDBx:U12>-0.0182</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.1662</PDBx:U22>
         <PDBx:U23>-0.0086</PDBx:U23>
         <PDBx:U33>0.1768</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>598</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1646">
         <PDBx:U11>0.1994</PDBx:U11>
         <PDBx:U12>-0.0070</PDBx:U12>
         <PDBx:U13>0.0186</PDBx:U13>
         <PDBx:U22>0.1758</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.1853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>598</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1647">
         <PDBx:U11>0.2195</PDBx:U11>
         <PDBx:U12>0.0180</PDBx:U12>
         <PDBx:U13>0.0062</PDBx:U13>
         <PDBx:U22>0.1838</PDBx:U22>
         <PDBx:U23>0.0065</PDBx:U23>
         <PDBx:U33>0.1963</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>598</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1648">
         <PDBx:U11>0.2208</PDBx:U11>
         <PDBx:U12>0.0069</PDBx:U12>
         <PDBx:U13>0.0333</PDBx:U13>
         <PDBx:U22>0.2054</PDBx:U22>
         <PDBx:U23>-0.0204</PDBx:U23>
         <PDBx:U33>0.2119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>599</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1649">
         <PDBx:U11>0.1896</PDBx:U11>
         <PDBx:U12>-0.0003</PDBx:U12>
         <PDBx:U13>-0.0088</PDBx:U13>
         <PDBx:U22>0.2546</PDBx:U22>
         <PDBx:U23>-0.0711</PDBx:U23>
         <PDBx:U33>0.2283</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>599</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1650">
         <PDBx:U11>0.2090</PDBx:U11>
         <PDBx:U12>-0.0222</PDBx:U12>
         <PDBx:U13>0.0184</PDBx:U13>
         <PDBx:U22>0.2391</PDBx:U22>
         <PDBx:U23>-0.0558</PDBx:U23>
         <PDBx:U33>0.2395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>599</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1651">
         <PDBx:U11>0.1981</PDBx:U11>
         <PDBx:U12>-0.0227</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.2882</PDBx:U22>
         <PDBx:U23>-0.0408</PDBx:U23>
         <PDBx:U33>0.3559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>599</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1652">
         <PDBx:U11>0.2665</PDBx:U11>
         <PDBx:U12>-0.0170</PDBx:U12>
         <PDBx:U13>-0.0064</PDBx:U13>
         <PDBx:U22>0.3235</PDBx:U22>
         <PDBx:U23>-0.0837</PDBx:U23>
         <PDBx:U33>0.2119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>599</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1653">
         <PDBx:U11>0.3965</PDBx:U11>
         <PDBx:U12>-0.0444</PDBx:U12>
         <PDBx:U13>0.0115</PDBx:U13>
         <PDBx:U22>0.4024</PDBx:U22>
         <PDBx:U23>0.0080</PDBx:U23>
         <PDBx:U33>0.3231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>599</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1654">
         <PDBx:U11>0.5205</PDBx:U11>
         <PDBx:U12>0.0968</PDBx:U12>
         <PDBx:U13>0.0568</PDBx:U13>
         <PDBx:U22>0.7512</PDBx:U22>
         <PDBx:U23>-0.3447</PDBx:U23>
         <PDBx:U33>0.2372</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>599</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1655">
         <PDBx:U11>0.5931</PDBx:U11>
         <PDBx:U12>0.0455</PDBx:U12>
         <PDBx:U13>-0.0662</PDBx:U13>
         <PDBx:U22>0.3949</PDBx:U22>
         <PDBx:U23>-0.0864</PDBx:U23>
         <PDBx:U33>0.6209</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>599</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1656">
         <PDBx:U11>0.6081</PDBx:U11>
         <PDBx:U12>-0.0473</PDBx:U12>
         <PDBx:U13>0.0825</PDBx:U13>
         <PDBx:U22>0.8343</PDBx:U22>
         <PDBx:U23>-0.3086</PDBx:U23>
         <PDBx:U33>0.2961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>599</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1657">
         <PDBx:U11>0.1996</PDBx:U11>
         <PDBx:U12>-0.0170</PDBx:U12>
         <PDBx:U13>0.0172</PDBx:U13>
         <PDBx:U22>0.2385</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.2117</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>600</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1658">
         <PDBx:U11>0.2476</PDBx:U11>
         <PDBx:U12>-0.0756</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.2684</PDBx:U22>
         <PDBx:U23>0.0148</PDBx:U23>
         <PDBx:U33>0.2504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>600</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1659">
         <PDBx:U11>0.2182</PDBx:U11>
         <PDBx:U12>-0.0379</PDBx:U12>
         <PDBx:U13>-0.0027</PDBx:U13>
         <PDBx:U22>0.2103</PDBx:U22>
         <PDBx:U23>-0.0350</PDBx:U23>
         <PDBx:U33>0.2554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>600</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1660">
         <PDBx:U11>0.2296</PDBx:U11>
         <PDBx:U12>-0.0771</PDBx:U12>
         <PDBx:U13>0.0260</PDBx:U13>
         <PDBx:U22>0.2599</PDBx:U22>
         <PDBx:U23>-0.0180</PDBx:U23>
         <PDBx:U33>0.2925</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>600</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1661">
         <PDBx:U11>0.3288</PDBx:U11>
         <PDBx:U12>-0.1228</PDBx:U12>
         <PDBx:U13>-0.0753</PDBx:U13>
         <PDBx:U22>0.3142</PDBx:U22>
         <PDBx:U23>0.0638</PDBx:U23>
         <PDBx:U33>0.3160</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>600</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1662">
         <PDBx:U11>0.4266</PDBx:U11>
         <PDBx:U12>-0.1270</PDBx:U12>
         <PDBx:U13>-0.0387</PDBx:U13>
         <PDBx:U22>0.3765</PDBx:U22>
         <PDBx:U23>0.0554</PDBx:U23>
         <PDBx:U33>0.2857</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>600</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1663">
         <PDBx:U11>0.5771</PDBx:U11>
         <PDBx:U12>0.0483</PDBx:U12>
         <PDBx:U13>-0.0264</PDBx:U13>
         <PDBx:U22>0.3863</PDBx:U22>
         <PDBx:U23>0.0648</PDBx:U23>
         <PDBx:U33>0.4364</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>600</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1664">
         <PDBx:U11>0.6058</PDBx:U11>
         <PDBx:U12>0.0298</PDBx:U12>
         <PDBx:U13>0.0658</PDBx:U13>
         <PDBx:U22>0.5942</PDBx:U22>
         <PDBx:U23>0.1279</PDBx:U23>
         <PDBx:U33>0.4157</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>600</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1665">
         <PDBx:U11>0.5575</PDBx:U11>
         <PDBx:U12>0.0668</PDBx:U12>
         <PDBx:U13>0.0012</PDBx:U13>
         <PDBx:U22>0.6544</PDBx:U22>
         <PDBx:U23>-0.1095</PDBx:U23>
         <PDBx:U33>0.4605</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>600</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1666">
         <PDBx:U11>0.5716</PDBx:U11>
         <PDBx:U12>-0.0834</PDBx:U12>
         <PDBx:U13>0.0124</PDBx:U13>
         <PDBx:U22>0.6806</PDBx:U22>
         <PDBx:U23>-0.0574</PDBx:U23>
         <PDBx:U33>0.3929</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>600</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1667">
         <PDBx:U11>0.4292</PDBx:U11>
         <PDBx:U12>0.0561</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.4740</PDBx:U22>
         <PDBx:U23>-0.0715</PDBx:U23>
         <PDBx:U33>0.5480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>600</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1668">
         <PDBx:U11>0.2370</PDBx:U11>
         <PDBx:U12>0.0034</PDBx:U12>
         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.2449</PDBx:U22>
         <PDBx:U23>-0.0136</PDBx:U23>
         <PDBx:U33>0.2303</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1669">
         <PDBx:U11>0.2299</PDBx:U11>
         <PDBx:U12>-0.0157</PDBx:U12>
         <PDBx:U13>0.0222</PDBx:U13>
         <PDBx:U22>0.2373</PDBx:U22>
         <PDBx:U23>-0.0166</PDBx:U23>
         <PDBx:U33>0.2242</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1670">
         <PDBx:U11>0.2447</PDBx:U11>
         <PDBx:U12>0.0002</PDBx:U12>
         <PDBx:U13>0.0208</PDBx:U13>
         <PDBx:U22>0.2589</PDBx:U22>
         <PDBx:U23>-0.0254</PDBx:U23>
         <PDBx:U33>0.2268</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1671">
         <PDBx:U11>0.2096</PDBx:U11>
         <PDBx:U12>-0.0031</PDBx:U12>
         <PDBx:U13>-0.0079</PDBx:U13>
         <PDBx:U22>0.2607</PDBx:U22>
         <PDBx:U23>-0.0184</PDBx:U23>
         <PDBx:U33>0.2479</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1672">
         <PDBx:U11>0.2587</PDBx:U11>
         <PDBx:U12>0.0166</PDBx:U12>
         <PDBx:U13>0.0472</PDBx:U13>
         <PDBx:U22>0.2430</PDBx:U22>
         <PDBx:U23>-0.0449</PDBx:U23>
         <PDBx:U33>0.2518</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1673">
         <PDBx:U11>0.2712</PDBx:U11>
         <PDBx:U12>-0.0197</PDBx:U12>
         <PDBx:U13>0.0366</PDBx:U13>
         <PDBx:U22>0.2665</PDBx:U22>
         <PDBx:U23>-0.0264</PDBx:U23>
         <PDBx:U33>0.2998</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1674">
         <PDBx:U11>0.3962</PDBx:U11>
         <PDBx:U12>-0.0002</PDBx:U12>
         <PDBx:U13>0.0898</PDBx:U13>
         <PDBx:U22>0.2613</PDBx:U22>
         <PDBx:U23>0.0226</PDBx:U23>
         <PDBx:U33>0.4371</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0138</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.4072</PDBx:U11>
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         <PDBx:U13>0.0569</PDBx:U13>
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         <PDBx:U23>0.0350</PDBx:U23>
         <PDBx:U33>0.5504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0277</PDBx:U13>
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         <PDBx:U23>0.0211</PDBx:U23>
         <PDBx:U33>0.4042</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0507</PDBx:U13>
         <PDBx:U22>0.3359</PDBx:U22>
         <PDBx:U23>0.0334</PDBx:U23>
         <PDBx:U33>0.4932</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0053</PDBx:U13>
         <PDBx:U22>0.2802</PDBx:U22>
         <PDBx:U23>-0.0267</PDBx:U23>
         <PDBx:U33>0.2480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>602</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.2900</PDBx:U22>
         <PDBx:U23>-0.0164</PDBx:U23>
         <PDBx:U33>0.2033</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>602</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0188</PDBx:U23>
         <PDBx:U33>0.2369</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>602</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0098</PDBx:U13>
         <PDBx:U22>0.3115</PDBx:U22>
         <PDBx:U23>-0.0186</PDBx:U23>
         <PDBx:U33>0.2317</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>602</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1683">
         <PDBx:U11>0.2066</PDBx:U11>
         <PDBx:U12>-0.0409</PDBx:U12>
         <PDBx:U13>-0.0022</PDBx:U13>
         <PDBx:U22>0.3104</PDBx:U22>
         <PDBx:U23>-0.0845</PDBx:U23>
         <PDBx:U33>0.2804</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>602</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1684">
         <PDBx:U11>0.2431</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>-0.0440</PDBx:U13>
         <PDBx:U22>0.3040</PDBx:U22>
         <PDBx:U23>-0.0685</PDBx:U23>
         <PDBx:U33>0.2731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>602</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.1936</PDBx:U11>
         <PDBx:U12>-0.0281</PDBx:U12>
         <PDBx:U13>-0.0093</PDBx:U13>
         <PDBx:U22>0.3036</PDBx:U22>
         <PDBx:U23>-0.0286</PDBx:U23>
         <PDBx:U33>0.2647</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>602</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1686">
         <PDBx:U11>0.2087</PDBx:U11>
         <PDBx:U12>0.0007</PDBx:U12>
         <PDBx:U13>0.0232</PDBx:U13>
         <PDBx:U22>0.3020</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.2208</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>603</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.2432</PDBx:U11>
         <PDBx:U12>0.0005</PDBx:U12>
         <PDBx:U13>0.0602</PDBx:U13>
         <PDBx:U22>0.3079</PDBx:U22>
         <PDBx:U23>0.0237</PDBx:U23>
         <PDBx:U33>0.2417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>603</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0209</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>603</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0387</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>603</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0032</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>603</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>608</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1724">
         <PDBx:U11>0.4291</PDBx:U11>
         <PDBx:U12>-0.0488</PDBx:U12>
         <PDBx:U13>0.0614</PDBx:U13>
         <PDBx:U22>0.4226</PDBx:U22>
         <PDBx:U23>-0.2406</PDBx:U23>
         <PDBx:U33>0.6342</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>608</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1725">
         <PDBx:U11>0.3669</PDBx:U11>
         <PDBx:U12>-0.0370</PDBx:U12>
         <PDBx:U13>0.1268</PDBx:U13>
         <PDBx:U22>0.3677</PDBx:U22>
         <PDBx:U23>-0.1201</PDBx:U23>
         <PDBx:U33>0.7334</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>608</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1726">
         <PDBx:U11>0.4531</PDBx:U11>
         <PDBx:U12>-0.0814</PDBx:U12>
         <PDBx:U13>-0.0930</PDBx:U13>
         <PDBx:U22>0.4059</PDBx:U22>
         <PDBx:U23>-0.0580</PDBx:U23>
         <PDBx:U33>0.8024</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>608</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1727">
         <PDBx:U11>0.5757</PDBx:U11>
         <PDBx:U12>-0.0521</PDBx:U12>
         <PDBx:U13>0.0243</PDBx:U13>
         <PDBx:U22>1.0724</PDBx:U22>
         <PDBx:U23>-0.2043</PDBx:U23>
         <PDBx:U33>0.9065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>608</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1728">
         <PDBx:U11>1.0073</PDBx:U11>
         <PDBx:U12>0.0731</PDBx:U12>
         <PDBx:U13>-0.0614</PDBx:U13>
         <PDBx:U22>1.0880</PDBx:U22>
         <PDBx:U23>-0.2512</PDBx:U23>
         <PDBx:U33>0.7904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>608</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1729">
         <PDBx:U11>0.6691</PDBx:U11>
         <PDBx:U12>-0.0792</PDBx:U12>
         <PDBx:U13>0.1062</PDBx:U13>
         <PDBx:U22>0.9859</PDBx:U22>
         <PDBx:U23>-0.1229</PDBx:U23>
         <PDBx:U33>0.8044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>608</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1730">
         <PDBx:U11>0.2631</PDBx:U11>
         <PDBx:U12>-0.0621</PDBx:U12>
         <PDBx:U13>0.0256</PDBx:U13>
         <PDBx:U22>0.3445</PDBx:U22>
         <PDBx:U23>-0.1111</PDBx:U23>
         <PDBx:U33>0.4029</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>609</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1731">
         <PDBx:U11>0.3524</PDBx:U11>
         <PDBx:U12>-0.0372</PDBx:U12>
         <PDBx:U13>0.0574</PDBx:U13>
         <PDBx:U22>0.3042</PDBx:U22>
         <PDBx:U23>-0.1111</PDBx:U23>
         <PDBx:U33>0.3760</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>609</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1732">
         <PDBx:U11>0.3176</PDBx:U11>
         <PDBx:U12>-0.0099</PDBx:U12>
         <PDBx:U13>0.0692</PDBx:U13>
         <PDBx:U22>0.2536</PDBx:U22>
         <PDBx:U23>-0.0308</PDBx:U23>
         <PDBx:U33>0.3837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>609</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1733">
         <PDBx:U11>0.2863</PDBx:U11>
         <PDBx:U12>0.0129</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.3489</PDBx:U22>
         <PDBx:U23>-0.0829</PDBx:U23>
         <PDBx:U33>0.3994</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>609</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1734">
         <PDBx:U11>0.2929</PDBx:U11>
         <PDBx:U12>0.0095</PDBx:U12>
         <PDBx:U13>0.0817</PDBx:U13>
         <PDBx:U22>0.2861</PDBx:U22>
         <PDBx:U23>-0.0952</PDBx:U23>
         <PDBx:U33>0.3741</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>609</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1735">
         <PDBx:U11>0.4070</PDBx:U11>
         <PDBx:U12>-0.0640</PDBx:U12>
         <PDBx:U13>0.0583</PDBx:U13>
         <PDBx:U22>0.3852</PDBx:U22>
         <PDBx:U23>-0.0255</PDBx:U23>
         <PDBx:U33>0.4003</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>609</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1736">
         <PDBx:U11>0.3892</PDBx:U11>
         <PDBx:U12>0.0361</PDBx:U12>
         <PDBx:U13>0.0851</PDBx:U13>
         <PDBx:U22>0.2956</PDBx:U22>
         <PDBx:U23>-0.0399</PDBx:U23>
         <PDBx:U33>0.4738</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>609</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1737">
         <PDBx:U11>0.4352</PDBx:U11>
         <PDBx:U12>0.0402</PDBx:U12>
         <PDBx:U13>0.0175</PDBx:U13>
         <PDBx:U22>0.2826</PDBx:U22>
         <PDBx:U23>-0.0336</PDBx:U23>
         <PDBx:U33>0.3947</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>609</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1738">
         <PDBx:U11>0.3295</PDBx:U11>
         <PDBx:U12>-0.0036</PDBx:U12>
         <PDBx:U13>0.1144</PDBx:U13>
         <PDBx:U22>0.2316</PDBx:U22>
         <PDBx:U23>-0.0928</PDBx:U23>
         <PDBx:U33>0.3972</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>609</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1739">
         <PDBx:U11>0.3527</PDBx:U11>
         <PDBx:U12>-0.0679</PDBx:U12>
         <PDBx:U13>0.0465</PDBx:U13>
         <PDBx:U22>0.3246</PDBx:U22>
         <PDBx:U23>-0.0375</PDBx:U23>
         <PDBx:U33>0.3618</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>609</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1740">
         <PDBx:U11>0.3311</PDBx:U11>
         <PDBx:U12>-0.0330</PDBx:U12>
         <PDBx:U13>0.0534</PDBx:U13>
         <PDBx:U22>0.3078</PDBx:U22>
         <PDBx:U23>-0.0897</PDBx:U23>
         <PDBx:U33>0.2512</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>610</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1741">
         <PDBx:U11>0.2789</PDBx:U11>
         <PDBx:U12>0.0010</PDBx:U12>
         <PDBx:U13>0.0224</PDBx:U13>
         <PDBx:U22>0.3319</PDBx:U22>
         <PDBx:U23>-0.1290</PDBx:U23>
         <PDBx:U33>0.1924</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>610</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1742">
         <PDBx:U11>0.3551</PDBx:U11>
         <PDBx:U12>0.0259</PDBx:U12>
         <PDBx:U13>0.0247</PDBx:U13>
         <PDBx:U22>0.4627</PDBx:U22>
         <PDBx:U23>-0.1482</PDBx:U23>
         <PDBx:U33>0.1792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>610</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1743">
         <PDBx:U11>0.3159</PDBx:U11>
         <PDBx:U12>0.0473</PDBx:U12>
         <PDBx:U13>0.0175</PDBx:U13>
         <PDBx:U22>0.4301</PDBx:U22>
         <PDBx:U23>-0.0875</PDBx:U23>
         <PDBx:U33>0.2801</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>610</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1744">
         <PDBx:U11>0.3796</PDBx:U11>
         <PDBx:U12>0.0253</PDBx:U12>
         <PDBx:U13>-0.0172</PDBx:U13>
         <PDBx:U22>0.3070</PDBx:U22>
         <PDBx:U23>-0.0477</PDBx:U23>
         <PDBx:U33>0.2805</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>610</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1745">
         <PDBx:U11>0.3016</PDBx:U11>
         <PDBx:U12>-0.0478</PDBx:U12>
         <PDBx:U13>-0.0574</PDBx:U13>
         <PDBx:U22>0.3146</PDBx:U22>
         <PDBx:U23>-0.0342</PDBx:U23>
         <PDBx:U33>0.3350</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>610</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1746">
         <PDBx:U11>0.3361</PDBx:U11>
         <PDBx:U12>-0.0843</PDBx:U12>
         <PDBx:U13>0.0403</PDBx:U13>
         <PDBx:U22>0.2941</PDBx:U22>
         <PDBx:U23>-0.0988</PDBx:U23>
         <PDBx:U33>0.3077</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>610</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1747">
         <PDBx:U11>0.3471</PDBx:U11>
         <PDBx:U12>-0.0586</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.3561</PDBx:U22>
         <PDBx:U23>-0.0562</PDBx:U23>
         <PDBx:U33>0.3710</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>610</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1748">
         <PDBx:U11>0.3870</PDBx:U11>
         <PDBx:U12>0.0672</PDBx:U12>
         <PDBx:U13>-0.0690</PDBx:U13>
         <PDBx:U22>0.4103</PDBx:U22>
         <PDBx:U23>-0.1114</PDBx:U23>
         <PDBx:U33>0.2390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>611</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1749">
         <PDBx:U11>0.3832</PDBx:U11>
         <PDBx:U12>0.1035</PDBx:U12>
         <PDBx:U13>-0.0813</PDBx:U13>
         <PDBx:U22>0.4779</PDBx:U22>
         <PDBx:U23>-0.1324</PDBx:U23>
         <PDBx:U33>0.2886</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>611</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1750">
         <PDBx:U11>0.4748</PDBx:U11>
         <PDBx:U12>0.0931</PDBx:U12>
         <PDBx:U13>0.0078</PDBx:U13>
         <PDBx:U22>0.4190</PDBx:U22>
         <PDBx:U23>-0.1364</PDBx:U23>
         <PDBx:U33>0.3259</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>611</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1751">
         <PDBx:U11>0.5119</PDBx:U11>
         <PDBx:U12>0.1543</PDBx:U12>
         <PDBx:U13>-0.0233</PDBx:U13>
         <PDBx:U22>0.5144</PDBx:U22>
         <PDBx:U23>-0.2243</PDBx:U23>
         <PDBx:U33>0.4547</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>611</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1752">
         <PDBx:U11>0.3776</PDBx:U11>
         <PDBx:U12>0.1954</PDBx:U12>
         <PDBx:U13>-0.1036</PDBx:U13>
         <PDBx:U22>0.5421</PDBx:U22>
         <PDBx:U23>-0.1041</PDBx:U23>
         <PDBx:U33>0.3338</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>611</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1753">
         <PDBx:U11>0.2938</PDBx:U11>
         <PDBx:U12>-0.0535</PDBx:U12>
         <PDBx:U13>-0.0304</PDBx:U13>
         <PDBx:U22>0.4504</PDBx:U22>
         <PDBx:U23>-0.1466</PDBx:U23>
         <PDBx:U33>0.3499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>612</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1754">
         <PDBx:U11>0.4784</PDBx:U11>
         <PDBx:U12>-0.0554</PDBx:U12>
         <PDBx:U13>-0.0797</PDBx:U13>
         <PDBx:U22>0.3596</PDBx:U22>
         <PDBx:U23>-0.1386</PDBx:U23>
         <PDBx:U33>0.6062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>612</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1755">
         <PDBx:U11>0.4128</PDBx:U11>
         <PDBx:U12>-0.0343</PDBx:U12>
         <PDBx:U13>0.0328</PDBx:U13>
         <PDBx:U22>0.3540</PDBx:U22>
         <PDBx:U23>-0.1016</PDBx:U23>
         <PDBx:U33>0.4760</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>612</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1756">
         <PDBx:U11>0.5091</PDBx:U11>
         <PDBx:U12>0.0372</PDBx:U12>
         <PDBx:U13>0.0300</PDBx:U13>
         <PDBx:U22>0.3321</PDBx:U22>
         <PDBx:U23>-0.1264</PDBx:U23>
         <PDBx:U33>0.5208</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>612</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1757">
         <PDBx:U11>0.4524</PDBx:U11>
         <PDBx:U12>-0.0378</PDBx:U12>
         <PDBx:U13>0.0069</PDBx:U13>
         <PDBx:U22>0.4503</PDBx:U22>
         <PDBx:U23>-0.1803</PDBx:U23>
         <PDBx:U33>0.6454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>612</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1758">
         <PDBx:U11>0.5433</PDBx:U11>
         <PDBx:U12>0.0128</PDBx:U12>
         <PDBx:U13>-0.0738</PDBx:U13>
         <PDBx:U22>0.6199</PDBx:U22>
         <PDBx:U23>-0.1953</PDBx:U23>
         <PDBx:U33>0.9269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>612</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1759">
         <PDBx:U11>0.7275</PDBx:U11>
         <PDBx:U12>0.0705</PDBx:U12>
         <PDBx:U13>0.0778</PDBx:U13>
         <PDBx:U22>0.5625</PDBx:U22>
         <PDBx:U23>-0.0411</PDBx:U23>
         <PDBx:U33>1.0400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>612</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1760">
         <PDBx:U11>0.7029</PDBx:U11>
         <PDBx:U12>0.2379</PDBx:U12>
         <PDBx:U13>0.0428</PDBx:U13>
         <PDBx:U22>0.7887</PDBx:U22>
         <PDBx:U23>0.0861</PDBx:U23>
         <PDBx:U33>1.1474</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>612</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1761">
         <PDBx:U11>0.8898</PDBx:U11>
         <PDBx:U12>0.0246</PDBx:U12>
         <PDBx:U13>-0.0569</PDBx:U13>
         <PDBx:U22>0.7615</PDBx:U22>
         <PDBx:U23>0.0462</PDBx:U23>
         <PDBx:U33>0.9596</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>612</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1762">
         <PDBx:U11>0.3515</PDBx:U11>
         <PDBx:U12>-0.0501</PDBx:U12>
         <PDBx:U13>0.0478</PDBx:U13>
         <PDBx:U22>0.3952</PDBx:U22>
         <PDBx:U23>-0.1147</PDBx:U23>
         <PDBx:U33>0.3361</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>613</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1763">
         <PDBx:U11>0.4406</PDBx:U11>
         <PDBx:U12>0.1027</PDBx:U12>
         <PDBx:U13>-0.0079</PDBx:U13>
         <PDBx:U22>0.4044</PDBx:U22>
         <PDBx:U23>-0.0855</PDBx:U23>
         <PDBx:U33>0.3493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>613</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1764">
         <PDBx:U11>0.3717</PDBx:U11>
         <PDBx:U12>-0.0146</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.3465</PDBx:U22>
         <PDBx:U23>-0.0868</PDBx:U23>
         <PDBx:U33>0.3937</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>613</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1765">
         <PDBx:U11>0.3760</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>-0.0058</PDBx:U13>
         <PDBx:U22>0.4127</PDBx:U22>
         <PDBx:U23>-0.0663</PDBx:U23>
         <PDBx:U33>0.3932</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>613</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1766">
         <PDBx:U11>0.3710</PDBx:U11>
         <PDBx:U12>-0.0836</PDBx:U12>
         <PDBx:U13>0.0411</PDBx:U13>
         <PDBx:U22>0.2791</PDBx:U22>
         <PDBx:U23>-0.1149</PDBx:U23>
         <PDBx:U33>0.3209</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>614</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1767">
         <PDBx:U11>0.3842</PDBx:U11>
         <PDBx:U12>-0.1008</PDBx:U12>
         <PDBx:U13>0.0304</PDBx:U13>
         <PDBx:U22>0.2970</PDBx:U22>
         <PDBx:U23>-0.0659</PDBx:U23>
         <PDBx:U33>0.3308</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>614</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1768">
         <PDBx:U11>0.2350</PDBx:U11>
         <PDBx:U12>-0.0163</PDBx:U12>
         <PDBx:U13>-0.0119</PDBx:U13>
         <PDBx:U22>0.2420</PDBx:U22>
         <PDBx:U23>-0.0315</PDBx:U23>
         <PDBx:U33>0.2798</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>614</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1769">
         <PDBx:U11>0.2402</PDBx:U11>
         <PDBx:U12>-0.0180</PDBx:U12>
         <PDBx:U13>-0.0045</PDBx:U13>
         <PDBx:U22>0.2651</PDBx:U22>
         <PDBx:U23>-0.0361</PDBx:U23>
         <PDBx:U33>0.2308</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>614</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1770">
         <PDBx:U11>0.3576</PDBx:U11>
         <PDBx:U12>-0.0520</PDBx:U12>
         <PDBx:U13>0.0447</PDBx:U13>
         <PDBx:U22>0.3273</PDBx:U22>
         <PDBx:U23>-0.0950</PDBx:U23>
         <PDBx:U33>0.3402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>614</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1771">
         <PDBx:U11>0.3639</PDBx:U11>
         <PDBx:U12>-0.0461</PDBx:U12>
         <PDBx:U13>0.0349</PDBx:U13>
         <PDBx:U22>0.2885</PDBx:U22>
         <PDBx:U23>-0.0409</PDBx:U23>
         <PDBx:U33>0.4369</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>614</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1772">
         <PDBx:U11>0.3942</PDBx:U11>
         <PDBx:U12>-0.0958</PDBx:U12>
         <PDBx:U13>0.0929</PDBx:U13>
         <PDBx:U22>0.3211</PDBx:U22>
         <PDBx:U23>-0.1042</PDBx:U23>
         <PDBx:U33>0.7382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>614</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1773">
         <PDBx:U11>0.4449</PDBx:U11>
         <PDBx:U12>-0.0745</PDBx:U12>
         <PDBx:U13>0.0498</PDBx:U13>
         <PDBx:U22>0.2046</PDBx:U22>
         <PDBx:U23>-0.0256</PDBx:U23>
         <PDBx:U33>0.4407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>614</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1774">
         <PDBx:U11>0.2099</PDBx:U11>
         <PDBx:U12>-0.0086</PDBx:U12>
         <PDBx:U13>0.0360</PDBx:U13>
         <PDBx:U22>0.1928</PDBx:U22>
         <PDBx:U23>-0.0413</PDBx:U23>
         <PDBx:U33>0.2502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>615</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1775">
         <PDBx:U11>0.2116</PDBx:U11>
         <PDBx:U12>0.0005</PDBx:U12>
         <PDBx:U13>0.0193</PDBx:U13>
         <PDBx:U22>0.1562</PDBx:U22>
         <PDBx:U23>-0.0264</PDBx:U23>
         <PDBx:U33>0.2427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>615</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1776">
         <PDBx:U11>0.2103</PDBx:U11>
         <PDBx:U12>0.0152</PDBx:U12>
         <PDBx:U13>0.0131</PDBx:U13>
         <PDBx:U22>0.1607</PDBx:U22>
         <PDBx:U23>0.0121</PDBx:U23>
         <PDBx:U33>0.2144</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>615</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1777">
         <PDBx:U11>0.2331</PDBx:U11>
         <PDBx:U12>-0.0516</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.2371</PDBx:U22>
         <PDBx:U23>-0.0137</PDBx:U23>
         <PDBx:U33>0.2408</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>615</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1778">
         <PDBx:U11>0.2222</PDBx:U11>
         <PDBx:U12>0.0215</PDBx:U12>
         <PDBx:U13>0.0227</PDBx:U13>
         <PDBx:U22>0.2267</PDBx:U22>
         <PDBx:U23>0.0073</PDBx:U23>
         <PDBx:U33>0.2192</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>615</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1779">
         <PDBx:U11>0.2200</PDBx:U11>
         <PDBx:U12>0.0166</PDBx:U12>
         <PDBx:U13>0.0267</PDBx:U13>
         <PDBx:U22>0.2046</PDBx:U22>
         <PDBx:U23>0.0149</PDBx:U23>
         <PDBx:U33>0.2106</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>615</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1780">
         <PDBx:U11>0.2390</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>0.0655</PDBx:U13>
         <PDBx:U22>0.1853</PDBx:U22>
         <PDBx:U23>0.0145</PDBx:U23>
         <PDBx:U33>0.2099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>615</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1781">
         <PDBx:U11>0.2341</PDBx:U11>
         <PDBx:U12>-0.0001</PDBx:U12>
         <PDBx:U13>0.0106</PDBx:U13>
         <PDBx:U22>0.2024</PDBx:U22>
         <PDBx:U23>-0.0241</PDBx:U23>
         <PDBx:U33>0.1973</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>615</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1782">
         <PDBx:U11>0.2397</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>0.0158</PDBx:U13>
         <PDBx:U22>0.1914</PDBx:U22>
         <PDBx:U23>-0.0200</PDBx:U23>
         <PDBx:U33>0.2181</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>615</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1783">
         <PDBx:U11>0.2358</PDBx:U11>
         <PDBx:U12>-0.0279</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.2714</PDBx:U22>
         <PDBx:U23>-0.0308</PDBx:U23>
         <PDBx:U33>0.2452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>615</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1784">
         <PDBx:U11>0.2415</PDBx:U11>
         <PDBx:U12>-0.0083</PDBx:U12>
         <PDBx:U13>0.0205</PDBx:U13>
         <PDBx:U22>0.1986</PDBx:U22>
         <PDBx:U23>-0.0349</PDBx:U23>
         <PDBx:U33>0.2395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>615</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1785">
         <PDBx:U11>0.1970</PDBx:U11>
         <PDBx:U12>0.0325</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.1896</PDBx:U22>
         <PDBx:U23>-0.0353</PDBx:U23>
         <PDBx:U33>0.2013</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>616</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1786">
         <PDBx:U11>0.2067</PDBx:U11>
         <PDBx:U12>-0.0020</PDBx:U12>
         <PDBx:U13>-0.0100</PDBx:U13>
         <PDBx:U22>0.1818</PDBx:U22>
         <PDBx:U23>0.0016</PDBx:U23>
         <PDBx:U33>0.1781</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>616</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1787">
         <PDBx:U11>0.2130</PDBx:U11>
         <PDBx:U12>-0.0020</PDBx:U12>
         <PDBx:U13>-0.0035</PDBx:U13>
         <PDBx:U22>0.1626</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.2007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>616</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1788">
         <PDBx:U11>0.2413</PDBx:U11>
         <PDBx:U12>0.0112</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.2173</PDBx:U22>
         <PDBx:U23>0.0073</PDBx:U23>
         <PDBx:U33>0.2186</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>616</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1789">
         <PDBx:U11>0.1883</PDBx:U11>
         <PDBx:U12>-0.0094</PDBx:U12>
         <PDBx:U13>-0.0230</PDBx:U13>
         <PDBx:U22>0.1693</PDBx:U22>
         <PDBx:U23>0.0287</PDBx:U23>
         <PDBx:U33>0.2025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>616</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1790">
         <PDBx:U11>0.1562</PDBx:U11>
         <PDBx:U12>0.0071</PDBx:U12>
         <PDBx:U13>-0.0060</PDBx:U13>
         <PDBx:U22>0.1557</PDBx:U22>
         <PDBx:U23>0.0084</PDBx:U23>
         <PDBx:U33>0.2035</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>616</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1791">
         <PDBx:U11>0.1749</PDBx:U11>
         <PDBx:U12>-0.0263</PDBx:U12>
         <PDBx:U13>0.0119</PDBx:U13>
         <PDBx:U22>0.1942</PDBx:U22>
         <PDBx:U23>-0.0131</PDBx:U23>
         <PDBx:U33>0.2004</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>616</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1792">
         <PDBx:U11>0.1823</PDBx:U11>
         <PDBx:U12>0.0370</PDBx:U12>
         <PDBx:U13>0.0126</PDBx:U13>
         <PDBx:U22>0.2041</PDBx:U22>
         <PDBx:U23>-0.0237</PDBx:U23>
         <PDBx:U33>0.2040</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>616</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1793">
         <PDBx:U11>0.2268</PDBx:U11>
         <PDBx:U12>-0.0133</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.1933</PDBx:U22>
         <PDBx:U23>0.0016</PDBx:U23>
         <PDBx:U33>0.1885</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>617</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1794">
         <PDBx:U11>0.2026</PDBx:U11>
         <PDBx:U12>-0.0152</PDBx:U12>
         <PDBx:U13>-0.0257</PDBx:U13>
         <PDBx:U22>0.1949</PDBx:U22>
         <PDBx:U23>0.0241</PDBx:U23>
         <PDBx:U33>0.2177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>617</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1795">
         <PDBx:U11>0.2595</PDBx:U11>
         <PDBx:U12>-0.0075</PDBx:U12>
         <PDBx:U13>-0.0427</PDBx:U13>
         <PDBx:U22>0.1846</PDBx:U22>
         <PDBx:U23>0.0159</PDBx:U23>
         <PDBx:U33>0.1930</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>617</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1796">
         <PDBx:U11>0.2277</PDBx:U11>
         <PDBx:U12>-0.0054</PDBx:U12>
         <PDBx:U13>-0.0284</PDBx:U13>
         <PDBx:U22>0.1699</PDBx:U22>
         <PDBx:U23>0.0078</PDBx:U23>
         <PDBx:U33>0.2461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>617</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1797">
         <PDBx:U11>0.2666</PDBx:U11>
         <PDBx:U12>-0.0559</PDBx:U12>
         <PDBx:U13>0.0157</PDBx:U13>
         <PDBx:U22>0.2346</PDBx:U22>
         <PDBx:U23>0.0306</PDBx:U23>
         <PDBx:U33>0.2391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>617</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1798">
         <PDBx:U11>0.3339</PDBx:U11>
         <PDBx:U12>-0.0320</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.2976</PDBx:U22>
         <PDBx:U23>0.0058</PDBx:U23>
         <PDBx:U33>0.3409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>617</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1799">
         <PDBx:U11>0.3881</PDBx:U11>
         <PDBx:U12>-0.0002</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.3760</PDBx:U22>
         <PDBx:U23>-0.1275</PDBx:U23>
         <PDBx:U33>0.4064</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>617</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1800">
         <PDBx:U11>0.3348</PDBx:U11>
         <PDBx:U12>0.0312</PDBx:U12>
         <PDBx:U13>0.0262</PDBx:U13>
         <PDBx:U22>0.3269</PDBx:U22>
         <PDBx:U23>0.0124</PDBx:U23>
         <PDBx:U33>0.3831</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>617</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1801">
         <PDBx:U11>0.3722</PDBx:U11>
         <PDBx:U12>0.0313</PDBx:U12>
         <PDBx:U13>-0.0303</PDBx:U13>
         <PDBx:U22>0.3599</PDBx:U22>
         <PDBx:U23>-0.1186</PDBx:U23>
         <PDBx:U33>0.3472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>617</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1802">
         <PDBx:U11>0.3221</PDBx:U11>
         <PDBx:U12>0.0155</PDBx:U12>
         <PDBx:U13>-0.0050</PDBx:U13>
         <PDBx:U22>0.3044</PDBx:U22>
         <PDBx:U23>-0.0569</PDBx:U23>
         <PDBx:U33>0.3904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>617</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1803">
         <PDBx:U11>0.3526</PDBx:U11>
         <PDBx:U12>0.0353</PDBx:U12>
         <PDBx:U13>-0.0147</PDBx:U13>
         <PDBx:U22>0.3618</PDBx:U22>
         <PDBx:U23>-0.0266</PDBx:U23>
         <PDBx:U33>0.3202</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>617</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1804">
         <PDBx:U11>0.4773</PDBx:U11>
         <PDBx:U12>-0.0471</PDBx:U12>
         <PDBx:U13>0.0882</PDBx:U13>
         <PDBx:U22>0.3241</PDBx:U22>
         <PDBx:U23>0.0196</PDBx:U23>
         <PDBx:U33>0.4116</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>617</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1805">
         <PDBx:U11>0.1916</PDBx:U11>
         <PDBx:U12>-0.0016</PDBx:U12>
         <PDBx:U13>-0.0179</PDBx:U13>
         <PDBx:U22>0.1733</PDBx:U22>
         <PDBx:U23>-0.0206</PDBx:U23>
         <PDBx:U33>0.1830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>618</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1806">
         <PDBx:U11>0.1777</PDBx:U11>
         <PDBx:U12>-0.0016</PDBx:U12>
         <PDBx:U13>-0.0163</PDBx:U13>
         <PDBx:U22>0.1604</PDBx:U22>
         <PDBx:U23>0.0051</PDBx:U23>
         <PDBx:U33>0.1741</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>618</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1807">
         <PDBx:U11>0.1781</PDBx:U11>
         <PDBx:U12>0.0051</PDBx:U12>
         <PDBx:U13>-0.0149</PDBx:U13>
         <PDBx:U22>0.1648</PDBx:U22>
         <PDBx:U23>0.0099</PDBx:U23>
         <PDBx:U33>0.2054</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>618</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1808">
         <PDBx:U11>0.2129</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>0.0090</PDBx:U13>
         <PDBx:U22>0.1870</PDBx:U22>
         <PDBx:U23>-0.0097</PDBx:U23>
         <PDBx:U33>0.2106</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>618</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1809">
         <PDBx:U11>0.2014</PDBx:U11>
         <PDBx:U12>0.0054</PDBx:U12>
         <PDBx:U13>-0.0422</PDBx:U13>
         <PDBx:U22>0.1661</PDBx:U22>
         <PDBx:U23>0.0057</PDBx:U23>
         <PDBx:U33>0.1735</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>618</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1810">
         <PDBx:U11>0.1795</PDBx:U11>
         <PDBx:U12>0.0218</PDBx:U12>
         <PDBx:U13>-0.0509</PDBx:U13>
         <PDBx:U22>0.1673</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.2211</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>618</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1811">
         <PDBx:U11>0.1870</PDBx:U11>
         <PDBx:U12>0.0127</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.1596</PDBx:U22>
         <PDBx:U23>0.0329</PDBx:U23>
         <PDBx:U33>0.1939</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>618</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1812">
         <PDBx:U11>0.2188</PDBx:U11>
         <PDBx:U12>0.0259</PDBx:U12>
         <PDBx:U13>0.0255</PDBx:U13>
         <PDBx:U22>0.1850</PDBx:U22>
         <PDBx:U23>0.0357</PDBx:U23>
         <PDBx:U33>0.1834</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>618</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1813">
         <PDBx:U11>0.2295</PDBx:U11>
         <PDBx:U12>-0.0073</PDBx:U12>
         <PDBx:U13>0.0176</PDBx:U13>
         <PDBx:U22>0.1684</PDBx:U22>
         <PDBx:U23>-0.0155</PDBx:U23>
         <PDBx:U33>0.2003</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>618</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1814">
         <PDBx:U11>0.2330</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>-0.0140</PDBx:U13>
         <PDBx:U22>0.1520</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.2059</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>618</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1815">
         <PDBx:U11>0.2523</PDBx:U11>
         <PDBx:U12>0.0153</PDBx:U12>
         <PDBx:U13>0.0108</PDBx:U13>
         <PDBx:U22>0.1922</PDBx:U22>
         <PDBx:U23>0.0185</PDBx:U23>
         <PDBx:U33>0.2450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>618</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1816">
         <PDBx:U11>0.1966</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0126</PDBx:U13>
         <PDBx:U22>0.1485</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.1715</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>619</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1817">
         <PDBx:U11>0.2017</PDBx:U11>
         <PDBx:U12>-0.0006</PDBx:U12>
         <PDBx:U13>0.0124</PDBx:U13>
         <PDBx:U22>0.1545</PDBx:U22>
         <PDBx:U23>0.0072</PDBx:U23>
         <PDBx:U33>0.1684</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>619</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1818">
         <PDBx:U11>0.1927</PDBx:U11>
         <PDBx:U12>-0.0016</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.1825</PDBx:U22>
         <PDBx:U23>0.0117</PDBx:U23>
         <PDBx:U33>0.1851</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>619</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1819">
         <PDBx:U11>0.2059</PDBx:U11>
         <PDBx:U12>0.0081</PDBx:U12>
         <PDBx:U13>0.0082</PDBx:U13>
         <PDBx:U22>0.1649</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.1764</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>619</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1820">
         <PDBx:U11>0.2596</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0418</PDBx:U13>
         <PDBx:U22>0.1622</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.1828</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>619</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1821">
         <PDBx:U11>0.1938</PDBx:U11>
         <PDBx:U12>0.0228</PDBx:U12>
         <PDBx:U13>0.0140</PDBx:U13>
         <PDBx:U22>0.1598</PDBx:U22>
         <PDBx:U23>-0.0197</PDBx:U23>
         <PDBx:U33>0.1526</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>619</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1822">
         <PDBx:U11>0.1673</PDBx:U11>
         <PDBx:U12>0.0136</PDBx:U12>
         <PDBx:U13>0.0293</PDBx:U13>
         <PDBx:U22>0.1439</PDBx:U22>
         <PDBx:U23>0.0134</PDBx:U23>
         <PDBx:U33>0.1873</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>619</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1823">
         <PDBx:U11>0.2274</PDBx:U11>
         <PDBx:U12>-0.0403</PDBx:U12>
         <PDBx:U13>0.0091</PDBx:U13>
         <PDBx:U22>0.1772</PDBx:U22>
         <PDBx:U23>-0.0225</PDBx:U23>
         <PDBx:U33>0.1854</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>620</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1824">
         <PDBx:U11>0.1843</PDBx:U11>
         <PDBx:U12>-0.0124</PDBx:U12>
         <PDBx:U13>0.0192</PDBx:U13>
         <PDBx:U22>0.2278</PDBx:U22>
         <PDBx:U23>-0.0129</PDBx:U23>
         <PDBx:U33>0.1748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>620</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1825">
         <PDBx:U11>0.2095</PDBx:U11>
         <PDBx:U12>-0.0166</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.1751</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.1785</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>620</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1826">
         <PDBx:U11>0.2203</PDBx:U11>
         <PDBx:U12>-0.0156</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.1829</PDBx:U22>
         <PDBx:U23>0.0203</PDBx:U23>
         <PDBx:U33>0.2161</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>620</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1827">
         <PDBx:U11>0.2075</PDBx:U11>
         <PDBx:U12>-0.0323</PDBx:U12>
         <PDBx:U13>0.0460</PDBx:U13>
         <PDBx:U22>0.2114</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1971</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>620</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1828">
         <PDBx:U11>0.2369</PDBx:U11>
         <PDBx:U12>-0.0500</PDBx:U12>
         <PDBx:U13>0.0374</PDBx:U13>
         <PDBx:U22>0.2085</PDBx:U22>
         <PDBx:U23>0.0184</PDBx:U23>
         <PDBx:U33>0.2451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>620</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1829">
         <PDBx:U11>0.2991</PDBx:U11>
         <PDBx:U12>-0.0604</PDBx:U12>
         <PDBx:U13>0.0241</PDBx:U13>
         <PDBx:U22>0.2528</PDBx:U22>
         <PDBx:U23>-0.0016</PDBx:U23>
         <PDBx:U33>0.2650</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>620</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1830">
         <PDBx:U11>0.2802</PDBx:U11>
         <PDBx:U12>-0.0277</PDBx:U12>
         <PDBx:U13>0.0038</PDBx:U13>
         <PDBx:U22>0.2706</PDBx:U22>
         <PDBx:U23>0.0207</PDBx:U23>
         <PDBx:U33>0.2776</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>620</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1831">
         <PDBx:U11>0.2730</PDBx:U11>
         <PDBx:U12>-0.0489</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.2831</PDBx:U22>
         <PDBx:U23>0.0098</PDBx:U23>
         <PDBx:U33>0.3257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>620</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1832">
         <PDBx:U11>0.2975</PDBx:U11>
         <PDBx:U12>-0.0573</PDBx:U12>
         <PDBx:U13>0.0603</PDBx:U13>
         <PDBx:U22>0.2751</PDBx:U22>
         <PDBx:U23>0.0446</PDBx:U23>
         <PDBx:U33>0.3639</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>620</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1833">
         <PDBx:U11>0.1935</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0121</PDBx:U13>
         <PDBx:U22>0.1697</PDBx:U22>
         <PDBx:U23>0.0099</PDBx:U23>
         <PDBx:U33>0.1737</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>621</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1834">
         <PDBx:U11>0.1719</PDBx:U11>
         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>0.0103</PDBx:U13>
         <PDBx:U22>0.1722</PDBx:U22>
         <PDBx:U23>-0.0142</PDBx:U23>
         <PDBx:U33>0.2079</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>621</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1835">
         <PDBx:U11>0.2015</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>0.0095</PDBx:U13>
         <PDBx:U22>0.1933</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.1868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>621</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1836">
         <PDBx:U11>0.2329</PDBx:U11>
         <PDBx:U12>-0.0023</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.2518</PDBx:U22>
         <PDBx:U23>-0.0255</PDBx:U23>
         <PDBx:U33>0.2150</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>621</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1837">
         <PDBx:U11>0.1954</PDBx:U11>
         <PDBx:U12>-0.0251</PDBx:U12>
         <PDBx:U13>0.0312</PDBx:U13>
         <PDBx:U22>0.1660</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.1949</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>621</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>621</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>621</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>621</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>622</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>-0.0057</PDBx:U13>
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         <PDBx:U23>0.0084</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>622</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0058</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>622</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>622</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U13>-0.0087</PDBx:U13>
         <PDBx:U22>0.2166</PDBx:U22>
         <PDBx:U23>0.0143</PDBx:U23>
         <PDBx:U33>0.1576</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>622</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>623</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>0.0089</PDBx:U13>
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         <PDBx:U23>0.0103</PDBx:U23>
         <PDBx:U33>0.1845</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>623</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0143</PDBx:U23>
         <PDBx:U33>0.1820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>623</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>623</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>623</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1854">
         <PDBx:U11>0.2087</PDBx:U11>
         <PDBx:U12>0.0234</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.1813</PDBx:U22>
         <PDBx:U23>0.0183</PDBx:U23>
         <PDBx:U33>0.2095</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>624</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1855">
         <PDBx:U11>0.2144</PDBx:U11>
         <PDBx:U12>0.0121</PDBx:U12>
         <PDBx:U13>0.0113</PDBx:U13>
         <PDBx:U22>0.1853</PDBx:U22>
         <PDBx:U23>0.0073</PDBx:U23>
         <PDBx:U33>0.2031</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>624</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1856">
         <PDBx:U11>0.2480</PDBx:U11>
         <PDBx:U12>0.0330</PDBx:U12>
         <PDBx:U13>-0.0105</PDBx:U13>
         <PDBx:U22>0.1748</PDBx:U22>
         <PDBx:U23>0.0512</PDBx:U23>
         <PDBx:U33>0.2384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>624</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1857">
         <PDBx:U11>0.1995</PDBx:U11>
         <PDBx:U12>0.0282</PDBx:U12>
         <PDBx:U13>0.0224</PDBx:U13>
         <PDBx:U22>0.1517</PDBx:U22>
         <PDBx:U23>0.0152</PDBx:U23>
         <PDBx:U33>0.2144</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>625</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1858">
         <PDBx:U11>0.1906</PDBx:U11>
         <PDBx:U12>0.0013</PDBx:U12>
         <PDBx:U13>0.0056</PDBx:U13>
         <PDBx:U22>0.1899</PDBx:U22>
         <PDBx:U23>0.0375</PDBx:U23>
         <PDBx:U33>0.2289</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>625</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1859">
         <PDBx:U11>0.1790</PDBx:U11>
         <PDBx:U12>0.0082</PDBx:U12>
         <PDBx:U13>-0.0120</PDBx:U13>
         <PDBx:U22>0.1921</PDBx:U22>
         <PDBx:U23>0.0024</PDBx:U23>
         <PDBx:U33>0.1993</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>625</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1860">
         <PDBx:U11>0.2385</PDBx:U11>
         <PDBx:U12>0.0108</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.2155</PDBx:U22>
         <PDBx:U23>0.0219</PDBx:U23>
         <PDBx:U33>0.2078</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>625</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1861">
         <PDBx:U11>0.1935</PDBx:U11>
         <PDBx:U12>0.0162</PDBx:U12>
         <PDBx:U13>-0.0216</PDBx:U13>
         <PDBx:U22>0.2385</PDBx:U22>
         <PDBx:U23>0.0131</PDBx:U23>
         <PDBx:U33>0.2266</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>625</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1862">
         <PDBx:U11>0.1868</PDBx:U11>
         <PDBx:U12>0.0067</PDBx:U12>
         <PDBx:U13>-0.0242</PDBx:U13>
         <PDBx:U22>0.1716</PDBx:U22>
         <PDBx:U23>0.0058</PDBx:U23>
         <PDBx:U33>0.2114</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>626</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1863">
         <PDBx:U11>0.1793</PDBx:U11>
         <PDBx:U12>0.0100</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.1712</PDBx:U22>
         <PDBx:U23>0.0113</PDBx:U23>
         <PDBx:U33>0.1843</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>626</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1864">
         <PDBx:U11>0.2100</PDBx:U11>
         <PDBx:U12>0.0052</PDBx:U12>
         <PDBx:U13>0.0124</PDBx:U13>
         <PDBx:U22>0.1916</PDBx:U22>
         <PDBx:U23>0.0081</PDBx:U23>
         <PDBx:U33>0.1869</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>626</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1865">
         <PDBx:U11>0.2113</PDBx:U11>
         <PDBx:U12>-0.0024</PDBx:U12>
         <PDBx:U13>0.0096</PDBx:U13>
         <PDBx:U22>0.1907</PDBx:U22>
         <PDBx:U23>0.0164</PDBx:U23>
         <PDBx:U33>0.1882</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>626</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1866">
         <PDBx:U11>0.1705</PDBx:U11>
         <PDBx:U12>0.0044</PDBx:U12>
         <PDBx:U13>-0.0180</PDBx:U13>
         <PDBx:U22>0.1506</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.1986</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>626</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1867">
         <PDBx:U11>0.1873</PDBx:U11>
         <PDBx:U12>0.0158</PDBx:U12>
         <PDBx:U13>-0.0104</PDBx:U13>
         <PDBx:U22>0.1849</PDBx:U22>
         <PDBx:U23>0.0261</PDBx:U23>
         <PDBx:U33>0.2151</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>626</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1868">
         <PDBx:U11>0.2012</PDBx:U11>
         <PDBx:U12>-0.0085</PDBx:U12>
         <PDBx:U13>-0.0364</PDBx:U13>
         <PDBx:U22>0.1877</PDBx:U22>
         <PDBx:U23>0.0096</PDBx:U23>
         <PDBx:U33>0.1937</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>626</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1869">
         <PDBx:U11>0.1684</PDBx:U11>
         <PDBx:U12>0.0182</PDBx:U12>
         <PDBx:U13>-0.0118</PDBx:U13>
         <PDBx:U22>0.1619</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.2285</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>627</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1870">
         <PDBx:U11>0.1871</PDBx:U11>
         <PDBx:U12>0.0057</PDBx:U12>
         <PDBx:U13>0.0185</PDBx:U13>
         <PDBx:U22>0.1812</PDBx:U22>
         <PDBx:U23>-0.0192</PDBx:U23>
         <PDBx:U33>0.2098</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>627</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1871">
         <PDBx:U11>0.1805</PDBx:U11>
         <PDBx:U12>0.0104</PDBx:U12>
         <PDBx:U13>0.0115</PDBx:U13>
         <PDBx:U22>0.1905</PDBx:U22>
         <PDBx:U23>0.0042</PDBx:U23>
         <PDBx:U33>0.1928</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>627</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1872">
         <PDBx:U11>0.2100</PDBx:U11>
         <PDBx:U12>0.0168</PDBx:U12>
         <PDBx:U13>-0.0195</PDBx:U13>
         <PDBx:U22>0.1989</PDBx:U22>
         <PDBx:U23>0.0284</PDBx:U23>
         <PDBx:U33>0.2145</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>627</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1873">
         <PDBx:U11>0.1769</PDBx:U11>
         <PDBx:U12>0.0248</PDBx:U12>
         <PDBx:U13>-0.0204</PDBx:U13>
         <PDBx:U22>0.1632</PDBx:U22>
         <PDBx:U23>0.0316</PDBx:U23>
         <PDBx:U33>0.2133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>627</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1874">
         <PDBx:U11>0.1812</PDBx:U11>
         <PDBx:U12>0.0175</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.1732</PDBx:U22>
         <PDBx:U23>0.0084</PDBx:U23>
         <PDBx:U33>0.2222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>627</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1875">
         <PDBx:U11>0.1429</PDBx:U11>
         <PDBx:U12>0.0179</PDBx:U12>
         <PDBx:U13>-0.0053</PDBx:U13>
         <PDBx:U22>0.1790</PDBx:U22>
         <PDBx:U23>-0.0109</PDBx:U23>
         <PDBx:U33>0.1964</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>627</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1876">
         <PDBx:U11>0.2470</PDBx:U11>
         <PDBx:U12>-0.0190</PDBx:U12>
         <PDBx:U13>-0.0054</PDBx:U13>
         <PDBx:U22>0.1979</PDBx:U22>
         <PDBx:U23>-0.0167</PDBx:U23>
         <PDBx:U33>0.2368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>627</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1877">
         <PDBx:U11>0.1678</PDBx:U11>
         <PDBx:U12>-0.0012</PDBx:U12>
         <PDBx:U13>-0.0066</PDBx:U13>
         <PDBx:U22>0.1827</PDBx:U22>
         <PDBx:U23>-0.0204</PDBx:U23>
         <PDBx:U33>0.2232</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>627</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1878">
         <PDBx:U11>0.2135</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>-0.0142</PDBx:U13>
         <PDBx:U22>0.1949</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.2570</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>627</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1879">
         <PDBx:U11>0.2272</PDBx:U11>
         <PDBx:U12>0.0279</PDBx:U12>
         <PDBx:U13>-0.0231</PDBx:U13>
         <PDBx:U22>0.1798</PDBx:U22>
         <PDBx:U23>-0.0384</PDBx:U23>
         <PDBx:U33>0.2086</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>627</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1880">
         <PDBx:U11>0.2250</PDBx:U11>
         <PDBx:U12>-0.0010</PDBx:U12>
         <PDBx:U13>-0.0272</PDBx:U13>
         <PDBx:U22>0.2296</PDBx:U22>
         <PDBx:U23>-0.0246</PDBx:U23>
         <PDBx:U33>0.2526</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>627</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1881">
         <PDBx:U11>0.2020</PDBx:U11>
         <PDBx:U12>0.0166</PDBx:U12>
         <PDBx:U13>0.0261</PDBx:U13>
         <PDBx:U22>0.1708</PDBx:U22>
         <PDBx:U23>0.0097</PDBx:U23>
         <PDBx:U33>0.2158</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>628</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1882">
         <PDBx:U11>0.2081</PDBx:U11>
         <PDBx:U12>0.0223</PDBx:U12>
         <PDBx:U13>0.0211</PDBx:U13>
         <PDBx:U22>0.1676</PDBx:U22>
         <PDBx:U23>0.0136</PDBx:U23>
         <PDBx:U33>0.2046</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>628</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1883">
         <PDBx:U11>0.2118</PDBx:U11>
         <PDBx:U12>0.0289</PDBx:U12>
         <PDBx:U13>0.0186</PDBx:U13>
         <PDBx:U22>0.1785</PDBx:U22>
         <PDBx:U23>0.0128</PDBx:U23>
         <PDBx:U33>0.2063</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>628</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1884">
         <PDBx:U11>0.2419</PDBx:U11>
         <PDBx:U12>0.0263</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.1795</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.2168</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>628</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1885">
         <PDBx:U11>0.2266</PDBx:U11>
         <PDBx:U12>0.0560</PDBx:U12>
         <PDBx:U13>0.0216</PDBx:U13>
         <PDBx:U22>0.1873</PDBx:U22>
         <PDBx:U23>0.0132</PDBx:U23>
         <PDBx:U33>0.2315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>628</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1886">
         <PDBx:U11>0.2808</PDBx:U11>
         <PDBx:U12>0.0432</PDBx:U12>
         <PDBx:U13>-0.0049</PDBx:U13>
         <PDBx:U22>0.2225</PDBx:U22>
         <PDBx:U23>0.0516</PDBx:U23>
         <PDBx:U33>0.2892</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>628</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1887">
         <PDBx:U11>0.2393</PDBx:U11>
         <PDBx:U12>0.0677</PDBx:U12>
         <PDBx:U13>0.0430</PDBx:U13>
         <PDBx:U22>0.2598</PDBx:U22>
         <PDBx:U23>0.0273</PDBx:U23>
         <PDBx:U33>0.2247</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>628</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>252</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1888">
         <PDBx:U11>0.1879</PDBx:U11>
         <PDBx:U12>0.0264</PDBx:U12>
         <PDBx:U13>0.0175</PDBx:U13>
         <PDBx:U22>0.1719</PDBx:U22>
         <PDBx:U23>0.0310</PDBx:U23>
         <PDBx:U33>0.2354</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>629</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1889">
         <PDBx:U11>0.2064</PDBx:U11>
         <PDBx:U12>0.0088</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.1717</PDBx:U22>
         <PDBx:U23>0.0071</PDBx:U23>
         <PDBx:U33>0.2095</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>629</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1890">
         <PDBx:U11>0.1918</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.1992</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.1842</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>629</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1891">
         <PDBx:U11>0.2070</PDBx:U11>
         <PDBx:U12>0.0108</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.1849</PDBx:U22>
         <PDBx:U23>0.0124</PDBx:U23>
         <PDBx:U33>0.1842</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>629</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1892">
         <PDBx:U11>0.2032</PDBx:U11>
         <PDBx:U12>-0.0090</PDBx:U12>
         <PDBx:U13>-0.0055</PDBx:U13>
         <PDBx:U22>0.1493</PDBx:U22>
         <PDBx:U23>0.0275</PDBx:U23>
         <PDBx:U33>0.1847</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>629</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1893">
         <PDBx:U11>0.2106</PDBx:U11>
         <PDBx:U12>-0.0106</PDBx:U12>
         <PDBx:U13>-0.0460</PDBx:U13>
         <PDBx:U22>0.1970</PDBx:U22>
         <PDBx:U23>0.0053</PDBx:U23>
         <PDBx:U33>0.2425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>629</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1894">
         <PDBx:U11>0.2055</PDBx:U11>
         <PDBx:U12>0.0051</PDBx:U12>
         <PDBx:U13>0.0240</PDBx:U13>
         <PDBx:U22>0.1299</PDBx:U22>
         <PDBx:U23>0.0276</PDBx:U23>
         <PDBx:U33>0.2250</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>629</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1895">
         <PDBx:U11>0.2563</PDBx:U11>
         <PDBx:U12>-0.0139</PDBx:U12>
         <PDBx:U13>-0.0556</PDBx:U13>
         <PDBx:U22>0.2419</PDBx:U22>
         <PDBx:U23>-0.0143</PDBx:U23>
         <PDBx:U33>0.2229</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>629</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>253</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1896">
         <PDBx:U11>0.1595</PDBx:U11>
         <PDBx:U12>-0.0033</PDBx:U12>
         <PDBx:U13>0.0104</PDBx:U13>
         <PDBx:U22>0.1880</PDBx:U22>
         <PDBx:U23>0.0233</PDBx:U23>
         <PDBx:U33>0.1839</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>630</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1897">
         <PDBx:U11>0.1631</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.1538</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.1890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>630</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1898">
         <PDBx:U11>0.1996</PDBx:U11>
         <PDBx:U12>0.0065</PDBx:U12>
         <PDBx:U13>-0.0013</PDBx:U13>
         <PDBx:U22>0.1562</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.1765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>630</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1899">
         <PDBx:U11>0.2205</PDBx:U11>
         <PDBx:U12>0.0122</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.1782</PDBx:U22>
         <PDBx:U23>0.0111</PDBx:U23>
         <PDBx:U33>0.1820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>630</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1900">
         <PDBx:U11>0.1755</PDBx:U11>
         <PDBx:U12>0.0180</PDBx:U12>
         <PDBx:U13>0.0263</PDBx:U13>
         <PDBx:U22>0.1594</PDBx:U22>
         <PDBx:U23>0.0197</PDBx:U23>
         <PDBx:U33>0.2455</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>630</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1901">
         <PDBx:U11>0.1973</PDBx:U11>
         <PDBx:U12>0.0133</PDBx:U12>
         <PDBx:U13>0.0221</PDBx:U13>
         <PDBx:U22>0.1659</PDBx:U22>
         <PDBx:U23>0.0254</PDBx:U23>
         <PDBx:U33>0.2211</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>630</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1902">
         <PDBx:U11>0.2142</PDBx:U11>
         <PDBx:U12>0.0088</PDBx:U12>
         <PDBx:U13>0.0222</PDBx:U13>
         <PDBx:U22>0.1956</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.2130</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>630</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1903">
         <PDBx:U11>0.2293</PDBx:U11>
         <PDBx:U12>0.0121</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.2092</PDBx:U22>
         <PDBx:U23>0.0140</PDBx:U23>
         <PDBx:U33>0.1995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>630</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>254</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1904">
         <PDBx:U11>0.2111</PDBx:U11>
         <PDBx:U12>0.0044</PDBx:U12>
         <PDBx:U13>-0.0131</PDBx:U13>
         <PDBx:U22>0.1541</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.2039</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>631</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1905">
         <PDBx:U11>0.2147</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>-0.0084</PDBx:U13>
         <PDBx:U22>0.1683</PDBx:U22>
         <PDBx:U23>0.0147</PDBx:U23>
         <PDBx:U33>0.1582</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>631</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1906">
         <PDBx:U11>0.1985</PDBx:U11>
         <PDBx:U12>0.0226</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.1537</PDBx:U22>
         <PDBx:U23>0.0057</PDBx:U23>
         <PDBx:U33>0.2060</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>631</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1907">
         <PDBx:U11>0.2174</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>-0.0157</PDBx:U13>
         <PDBx:U22>0.1845</PDBx:U22>
         <PDBx:U23>0.0046</PDBx:U23>
         <PDBx:U33>0.2119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>631</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1908">
         <PDBx:U11>0.2490</PDBx:U11>
         <PDBx:U12>-0.0137</PDBx:U12>
         <PDBx:U13>-0.0174</PDBx:U13>
         <PDBx:U22>0.1573</PDBx:U22>
         <PDBx:U23>0.0371</PDBx:U23>
         <PDBx:U33>0.2162</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>631</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1909">
         <PDBx:U11>0.2641</PDBx:U11>
         <PDBx:U12>-0.0085</PDBx:U12>
         <PDBx:U13>-0.0027</PDBx:U13>
         <PDBx:U22>0.1732</PDBx:U22>
         <PDBx:U23>0.0304</PDBx:U23>
         <PDBx:U33>0.2407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>631</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1910">
         <PDBx:U11>0.3244</PDBx:U11>
         <PDBx:U12>-0.0489</PDBx:U12>
         <PDBx:U13>0.0221</PDBx:U13>
         <PDBx:U22>0.1863</PDBx:U22>
         <PDBx:U23>0.0025</PDBx:U23>
         <PDBx:U33>0.2710</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>631</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1911">
         <PDBx:U11>0.2553</PDBx:U11>
         <PDBx:U12>-0.0055</PDBx:U12>
         <PDBx:U13>-0.0441</PDBx:U13>
         <PDBx:U22>0.2052</PDBx:U22>
         <PDBx:U23>0.0060</PDBx:U23>
         <PDBx:U33>0.2983</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>631</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1912">
         <PDBx:U11>0.4022</PDBx:U11>
         <PDBx:U12>-0.1029</PDBx:U12>
         <PDBx:U13>-0.0155</PDBx:U13>
         <PDBx:U22>0.3007</PDBx:U22>
         <PDBx:U23>-0.0143</PDBx:U23>
         <PDBx:U33>0.3191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>631</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1913">
         <PDBx:U11>0.2860</PDBx:U11>
         <PDBx:U12>-0.0294</PDBx:U12>
         <PDBx:U13>-0.0488</PDBx:U13>
         <PDBx:U22>0.1821</PDBx:U22>
         <PDBx:U23>0.0176</PDBx:U23>
         <PDBx:U33>0.3553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>631</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1914">
         <PDBx:U11>0.3402</PDBx:U11>
         <PDBx:U12>-0.0418</PDBx:U12>
         <PDBx:U13>-0.0631</PDBx:U13>
         <PDBx:U22>0.3139</PDBx:U22>
         <PDBx:U23>-0.1017</PDBx:U23>
         <PDBx:U33>0.3954</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>631</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1915">
         <PDBx:U11>0.4283</PDBx:U11>
         <PDBx:U12>-0.0693</PDBx:U12>
         <PDBx:U13>-0.1335</PDBx:U13>
         <PDBx:U22>0.3018</PDBx:U22>
         <PDBx:U23>-0.0570</PDBx:U23>
         <PDBx:U33>0.4808</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>631</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>255</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1916">
         <PDBx:U11>0.1916</PDBx:U11>
         <PDBx:U12>0.0152</PDBx:U12>
         <PDBx:U13>0.0200</PDBx:U13>
         <PDBx:U22>0.1787</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.2226</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>632</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>256</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1917">
         <PDBx:U11>0.1862</PDBx:U11>
         <PDBx:U12>-0.0009</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.1867</PDBx:U22>
         <PDBx:U23>0.0177</PDBx:U23>
         <PDBx:U33>0.1984</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>632</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>256</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1918">
         <PDBx:U11>0.1713</PDBx:U11>
         <PDBx:U12>0.0042</PDBx:U12>
         <PDBx:U13>0.0114</PDBx:U13>
         <PDBx:U22>0.1880</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.1919</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>632</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>256</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0265</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>632</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>256</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.1979</PDBx:U11>
         <PDBx:U12>0.0297</PDBx:U12>
         <PDBx:U13>-0.0191</PDBx:U13>
         <PDBx:U22>0.1752</PDBx:U22>
         <PDBx:U23>-0.0133</PDBx:U23>
         <PDBx:U33>0.2371</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>632</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>256</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2127</PDBx:U11>
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         <PDBx:U13>-0.0142</PDBx:U13>
         <PDBx:U22>0.1889</PDBx:U22>
         <PDBx:U23>0.0183</PDBx:U23>
         <PDBx:U33>0.2090</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>632</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>256</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.1546</PDBx:U11>
         <PDBx:U12>0.0072</PDBx:U12>
         <PDBx:U13>-0.0187</PDBx:U13>
         <PDBx:U22>0.1678</PDBx:U22>
         <PDBx:U23>0.0060</PDBx:U23>
         <PDBx:U33>0.1976</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>633</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1923">
         <PDBx:U11>0.1680</PDBx:U11>
         <PDBx:U12>0.0156</PDBx:U12>
         <PDBx:U13>0.0056</PDBx:U13>
         <PDBx:U22>0.1359</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.1711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>633</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U12>-0.0068</PDBx:U12>
         <PDBx:U13>-0.0044</PDBx:U13>
         <PDBx:U22>0.1594</PDBx:U22>
         <PDBx:U23>-0.0050</PDBx:U23>
         <PDBx:U33>0.1750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>633</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1925">
         <PDBx:U11>0.2248</PDBx:U11>
         <PDBx:U12>0.0248</PDBx:U12>
         <PDBx:U13>-0.0039</PDBx:U13>
         <PDBx:U22>0.1643</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.1853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>633</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1926">
         <PDBx:U11>0.1805</PDBx:U11>
         <PDBx:U12>0.0119</PDBx:U12>
         <PDBx:U13>0.0153</PDBx:U13>
         <PDBx:U22>0.1474</PDBx:U22>
         <PDBx:U23>-0.0378</PDBx:U23>
         <PDBx:U33>0.1910</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>633</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1927">
         <PDBx:U11>0.2048</PDBx:U11>
         <PDBx:U12>0.0028</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.1751</PDBx:U22>
         <PDBx:U23>-0.0040</PDBx:U23>
         <PDBx:U33>0.2005</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>633</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>257</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1928">
         <PDBx:U11>0.1897</PDBx:U11>
         <PDBx:U12>-0.0092</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.1557</PDBx:U22>
         <PDBx:U23>0.0057</PDBx:U23>
         <PDBx:U33>0.2052</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1929">
         <PDBx:U11>0.2118</PDBx:U11>
         <PDBx:U12>-0.0195</PDBx:U12>
         <PDBx:U13>0.0126</PDBx:U13>
         <PDBx:U22>0.1596</PDBx:U22>
         <PDBx:U23>-0.0076</PDBx:U23>
         <PDBx:U33>0.1873</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1930">
         <PDBx:U11>0.1977</PDBx:U11>
         <PDBx:U12>0.0178</PDBx:U12>
         <PDBx:U13>0.0224</PDBx:U13>
         <PDBx:U22>0.1714</PDBx:U22>
         <PDBx:U23>-0.0140</PDBx:U23>
         <PDBx:U33>0.2066</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1931">
         <PDBx:U11>0.2226</PDBx:U11>
         <PDBx:U12>0.0116</PDBx:U12>
         <PDBx:U13>0.0155</PDBx:U13>
         <PDBx:U22>0.1883</PDBx:U22>
         <PDBx:U23>-0.0241</PDBx:U23>
         <PDBx:U33>0.2370</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1932">
         <PDBx:U11>0.2334</PDBx:U11>
         <PDBx:U12>-0.0080</PDBx:U12>
         <PDBx:U13>0.0284</PDBx:U13>
         <PDBx:U22>0.1879</PDBx:U22>
         <PDBx:U23>-0.0365</PDBx:U23>
         <PDBx:U33>0.1887</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1933">
         <PDBx:U11>0.1958</PDBx:U11>
         <PDBx:U12>0.0033</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.1582</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1855</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1934">
         <PDBx:U11>0.2340</PDBx:U11>
         <PDBx:U12>0.0121</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.1679</PDBx:U22>
         <PDBx:U23>-0.0110</PDBx:U23>
         <PDBx:U33>0.2026</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1935">
         <PDBx:U11>0.2498</PDBx:U11>
         <PDBx:U12>-0.0062</PDBx:U12>
         <PDBx:U13>0.0224</PDBx:U13>
         <PDBx:U22>0.1717</PDBx:U22>
         <PDBx:U23>-0.0166</PDBx:U23>
         <PDBx:U33>0.1807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1936">
         <PDBx:U11>0.2257</PDBx:U11>
         <PDBx:U12>0.0028</PDBx:U12>
         <PDBx:U13>0.0347</PDBx:U13>
         <PDBx:U22>0.1445</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.2045</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1937">
         <PDBx:U11>0.2070</PDBx:U11>
         <PDBx:U12>-0.0075</PDBx:U12>
         <PDBx:U13>0.0100</PDBx:U13>
         <PDBx:U22>0.1610</PDBx:U22>
         <PDBx:U23>0.0035</PDBx:U23>
         <PDBx:U33>0.1771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1938">
         <PDBx:U11>0.2117</PDBx:U11>
         <PDBx:U12>-0.0190</PDBx:U12>
         <PDBx:U13>0.0332</PDBx:U13>
         <PDBx:U22>0.1625</PDBx:U22>
         <PDBx:U23>-0.0158</PDBx:U23>
         <PDBx:U33>0.2038</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1939">
         <PDBx:U11>0.1717</PDBx:U11>
         <PDBx:U12>0.0056</PDBx:U12>
         <PDBx:U13>0.0228</PDBx:U13>
         <PDBx:U22>0.1723</PDBx:U22>
         <PDBx:U23>0.0024</PDBx:U23>
         <PDBx:U33>0.1902</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1940">
         <PDBx:U11>0.2256</PDBx:U11>
         <PDBx:U12>0.0218</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.1710</PDBx:U22>
         <PDBx:U23>-0.0294</PDBx:U23>
         <PDBx:U33>0.1826</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1941">
         <PDBx:U11>0.2450</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>0.0110</PDBx:U13>
         <PDBx:U22>0.1645</PDBx:U22>
         <PDBx:U23>-0.0099</PDBx:U23>
         <PDBx:U33>0.2096</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>634</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>258</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1942">
         <PDBx:U11>0.1993</PDBx:U11>
         <PDBx:U12>0.0245</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.1442</PDBx:U22>
         <PDBx:U23>-0.0207</PDBx:U23>
         <PDBx:U33>0.2282</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>635</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1943">
         <PDBx:U11>0.2167</PDBx:U11>
         <PDBx:U12>0.0283</PDBx:U12>
         <PDBx:U13>0.0032</PDBx:U13>
         <PDBx:U22>0.1827</PDBx:U22>
         <PDBx:U23>-0.0550</PDBx:U23>
         <PDBx:U33>0.2328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>635</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1944">
         <PDBx:U11>0.2295</PDBx:U11>
         <PDBx:U12>-0.0004</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
         <PDBx:U22>0.1975</PDBx:U22>
         <PDBx:U23>-0.0213</PDBx:U23>
         <PDBx:U33>0.2317</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>635</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1945">
         <PDBx:U11>0.2316</PDBx:U11>
         <PDBx:U12>0.0088</PDBx:U12>
         <PDBx:U13>-0.0126</PDBx:U13>
         <PDBx:U22>0.2023</PDBx:U22>
         <PDBx:U23>-0.0131</PDBx:U23>
         <PDBx:U33>0.2359</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>635</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1946">
         <PDBx:U11>0.2353</PDBx:U11>
         <PDBx:U12>0.0469</PDBx:U12>
         <PDBx:U13>0.0222</PDBx:U13>
         <PDBx:U22>0.2166</PDBx:U22>
         <PDBx:U23>-0.0126</PDBx:U23>
         <PDBx:U33>0.2679</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>635</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1947">
         <PDBx:U11>0.3145</PDBx:U11>
         <PDBx:U12>0.0598</PDBx:U12>
         <PDBx:U13>0.0169</PDBx:U13>
         <PDBx:U22>0.2243</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.2953</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>635</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1948">
         <PDBx:U11>0.3517</PDBx:U11>
         <PDBx:U12>0.0262</PDBx:U12>
         <PDBx:U13>0.0392</PDBx:U13>
         <PDBx:U22>0.2903</PDBx:U22>
         <PDBx:U23>0.0156</PDBx:U23>
         <PDBx:U33>0.2844</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>635</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1949">
         <PDBx:U11>0.3389</PDBx:U11>
         <PDBx:U12>0.0920</PDBx:U12>
         <PDBx:U13>-0.0519</PDBx:U13>
         <PDBx:U22>0.2890</PDBx:U22>
         <PDBx:U23>-0.0408</PDBx:U23>
         <PDBx:U33>0.3482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>635</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1950">
         <PDBx:U11>0.4614</PDBx:U11>
         <PDBx:U12>0.0475</PDBx:U12>
         <PDBx:U13>0.0193</PDBx:U13>
         <PDBx:U22>0.2585</PDBx:U22>
         <PDBx:U23>-0.0520</PDBx:U23>
         <PDBx:U33>0.3521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>635</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1951">
         <PDBx:U11>0.4302</PDBx:U11>
         <PDBx:U12>0.0855</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.2589</PDBx:U22>
         <PDBx:U23>-0.0425</PDBx:U23>
         <PDBx:U33>0.3883</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>635</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>259</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1952">
         <PDBx:U11>0.2232</PDBx:U11>
         <PDBx:U12>-0.0015</PDBx:U12>
         <PDBx:U13>-0.0070</PDBx:U13>
         <PDBx:U22>0.2129</PDBx:U22>
         <PDBx:U23>-0.0521</PDBx:U23>
         <PDBx:U33>0.2602</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>636</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1953">
         <PDBx:U11>0.2575</PDBx:U11>
         <PDBx:U12>-0.0161</PDBx:U12>
         <PDBx:U13>0.0204</PDBx:U13>
         <PDBx:U22>0.2356</PDBx:U22>
         <PDBx:U23>-0.0270</PDBx:U23>
         <PDBx:U33>0.2423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>636</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1954">
         <PDBx:U11>0.2903</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>0.0243</PDBx:U13>
         <PDBx:U22>0.2545</PDBx:U22>
         <PDBx:U23>0.0075</PDBx:U23>
         <PDBx:U33>0.2466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>636</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1955">
         <PDBx:U11>0.3103</PDBx:U11>
         <PDBx:U12>0.0206</PDBx:U12>
         <PDBx:U13>0.0142</PDBx:U13>
         <PDBx:U22>0.2978</PDBx:U22>
         <PDBx:U23>0.0092</PDBx:U23>
         <PDBx:U33>0.2758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>636</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1956">
         <PDBx:U11>0.2596</PDBx:U11>
         <PDBx:U12>-0.0932</PDBx:U12>
         <PDBx:U13>0.0238</PDBx:U13>
         <PDBx:U22>0.2822</PDBx:U22>
         <PDBx:U23>-0.0581</PDBx:U23>
         <PDBx:U33>0.2748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>636</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1957">
         <PDBx:U11>0.6097</PDBx:U11>
         <PDBx:U12>-0.1250</PDBx:U12>
         <PDBx:U13>-0.0789</PDBx:U13>
         <PDBx:U22>0.4018</PDBx:U22>
         <PDBx:U23>-0.0824</PDBx:U23>
         <PDBx:U33>0.4062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>636</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1958">
         <PDBx:U11>0.8350</PDBx:U11>
         <PDBx:U12>-0.1812</PDBx:U12>
         <PDBx:U13>-0.0979</PDBx:U13>
         <PDBx:U22>0.3669</PDBx:U22>
         <PDBx:U23>-0.0537</PDBx:U23>
         <PDBx:U33>0.5183</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>636</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1959">
         <PDBx:U11>0.7838</PDBx:U11>
         <PDBx:U12>-0.0402</PDBx:U12>
         <PDBx:U13>-0.1456</PDBx:U13>
         <PDBx:U22>0.7434</PDBx:U22>
         <PDBx:U23>-0.1032</PDBx:U23>
         <PDBx:U33>0.5250</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>636</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1960">
         <PDBx:U11>0.7088</PDBx:U11>
         <PDBx:U12>-0.2006</PDBx:U12>
         <PDBx:U13>-0.0316</PDBx:U13>
         <PDBx:U22>0.3437</PDBx:U22>
         <PDBx:U23>0.0274</PDBx:U23>
         <PDBx:U33>0.6496</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>636</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>260</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1961">
         <PDBx:U11>0.2708</PDBx:U11>
         <PDBx:U12>-0.0330</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.2486</PDBx:U22>
         <PDBx:U23>-0.0538</PDBx:U23>
         <PDBx:U33>0.2498</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>637</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1962">
         <PDBx:U11>0.3077</PDBx:U11>
         <PDBx:U12>0.0160</PDBx:U12>
         <PDBx:U13>0.0250</PDBx:U13>
         <PDBx:U22>0.2514</PDBx:U22>
         <PDBx:U23>-0.0153</PDBx:U23>
         <PDBx:U33>0.2697</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>637</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1963">
         <PDBx:U11>0.2602</PDBx:U11>
         <PDBx:U12>-0.0086</PDBx:U12>
         <PDBx:U13>0.0119</PDBx:U13>
         <PDBx:U22>0.2511</PDBx:U22>
         <PDBx:U23>-0.0036</PDBx:U23>
         <PDBx:U33>0.2543</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>637</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1964">
         <PDBx:U11>0.2664</PDBx:U11>
         <PDBx:U12>0.0096</PDBx:U12>
         <PDBx:U13>0.0079</PDBx:U13>
         <PDBx:U22>0.2737</PDBx:U22>
         <PDBx:U23>-0.0074</PDBx:U23>
         <PDBx:U33>0.2468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>637</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1965">
         <PDBx:U11>0.3064</PDBx:U11>
         <PDBx:U12>0.0345</PDBx:U12>
         <PDBx:U13>-0.0078</PDBx:U13>
         <PDBx:U22>0.2619</PDBx:U22>
         <PDBx:U23>-0.0280</PDBx:U23>
         <PDBx:U33>0.3985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>637</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1966">
         <PDBx:U11>0.3988</PDBx:U11>
         <PDBx:U12>-0.0266</PDBx:U12>
         <PDBx:U13>-0.1011</PDBx:U13>
         <PDBx:U22>0.3138</PDBx:U22>
         <PDBx:U23>-0.0407</PDBx:U23>
         <PDBx:U33>0.5513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>637</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1967">
         <PDBx:U11>0.4634</PDBx:U11>
         <PDBx:U12>0.0934</PDBx:U12>
         <PDBx:U13>-0.0231</PDBx:U13>
         <PDBx:U22>0.4770</PDBx:U22>
         <PDBx:U23>-0.1789</PDBx:U23>
         <PDBx:U33>0.6143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>637</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1968">
         <PDBx:U11>0.6662</PDBx:U11>
         <PDBx:U12>0.1181</PDBx:U12>
         <PDBx:U13>-0.0965</PDBx:U13>
         <PDBx:U22>0.5243</PDBx:U22>
         <PDBx:U23>-0.0615</PDBx:U23>
         <PDBx:U33>0.9240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>637</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1969">
         <PDBx:U11>0.6250</PDBx:U11>
         <PDBx:U12>0.1346</PDBx:U12>
         <PDBx:U13>-0.0197</PDBx:U13>
         <PDBx:U22>0.5540</PDBx:U22>
         <PDBx:U23>-0.1069</PDBx:U23>
         <PDBx:U33>0.6073</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>637</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>261</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1970">
         <PDBx:U11>0.2739</PDBx:U11>
         <PDBx:U12>-0.0106</PDBx:U12>
         <PDBx:U13>0.0386</PDBx:U13>
         <PDBx:U22>0.2525</PDBx:U22>
         <PDBx:U23>-0.0192</PDBx:U23>
         <PDBx:U33>0.2677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>638</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1971">
         <PDBx:U11>0.2963</PDBx:U11>
         <PDBx:U12>0.0444</PDBx:U12>
         <PDBx:U13>-0.0154</PDBx:U13>
         <PDBx:U22>0.2045</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.2737</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>638</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1972">
         <PDBx:U11>0.2958</PDBx:U11>
         <PDBx:U12>-0.0164</PDBx:U12>
         <PDBx:U13>0.0228</PDBx:U13>
         <PDBx:U22>0.2374</PDBx:U22>
         <PDBx:U23>-0.0253</PDBx:U23>
         <PDBx:U33>0.2066</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>638</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1973">
         <PDBx:U11>0.2931</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.2201</PDBx:U22>
         <PDBx:U23>-0.0117</PDBx:U23>
         <PDBx:U33>0.2195</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>638</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1974">
         <PDBx:U11>0.3299</PDBx:U11>
         <PDBx:U12>0.0488</PDBx:U12>
         <PDBx:U13>0.0267</PDBx:U13>
         <PDBx:U22>0.2223</PDBx:U22>
         <PDBx:U23>0.0212</PDBx:U23>
         <PDBx:U33>0.2661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>638</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>262</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1975">
         <PDBx:U11>0.2763</PDBx:U11>
         <PDBx:U12>0.0260</PDBx:U12>
         <PDBx:U13>0.0461</PDBx:U13>
         <PDBx:U22>0.2591</PDBx:U22>
         <PDBx:U23>-0.0180</PDBx:U23>
         <PDBx:U33>0.2409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>639</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1976">
         <PDBx:U11>0.2939</PDBx:U11>
         <PDBx:U12>0.0255</PDBx:U12>
         <PDBx:U13>0.0163</PDBx:U13>
         <PDBx:U22>0.3184</PDBx:U22>
         <PDBx:U23>-0.0348</PDBx:U23>
         <PDBx:U33>0.2560</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>639</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1977">
         <PDBx:U11>0.3111</PDBx:U11>
         <PDBx:U12>0.0035</PDBx:U12>
         <PDBx:U13>0.0251</PDBx:U13>
         <PDBx:U22>0.2850</PDBx:U22>
         <PDBx:U23>-0.0115</PDBx:U23>
         <PDBx:U33>0.3028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>639</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1978">
         <PDBx:U11>0.3218</PDBx:U11>
         <PDBx:U12>0.0080</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.3532</PDBx:U22>
         <PDBx:U23>-0.0596</PDBx:U23>
         <PDBx:U33>0.3133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>639</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1979">
         <PDBx:U11>0.3461</PDBx:U11>
         <PDBx:U12>-0.0481</PDBx:U12>
         <PDBx:U13>0.0579</PDBx:U13>
         <PDBx:U22>0.3925</PDBx:U22>
         <PDBx:U23>-0.1004</PDBx:U23>
         <PDBx:U33>0.2748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>639</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1980">
         <PDBx:U11>0.6440</PDBx:U11>
         <PDBx:U12>-0.0601</PDBx:U12>
         <PDBx:U13>0.1051</PDBx:U13>
         <PDBx:U22>0.5194</PDBx:U22>
         <PDBx:U23>-0.1322</PDBx:U23>
         <PDBx:U33>0.4860</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>639</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1981">
         <PDBx:U11>0.7502</PDBx:U11>
         <PDBx:U12>-0.0405</PDBx:U12>
         <PDBx:U13>0.0302</PDBx:U13>
         <PDBx:U22>0.5183</PDBx:U22>
         <PDBx:U23>-0.1372</PDBx:U23>
         <PDBx:U33>0.5398</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>639</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1982">
         <PDBx:U11>0.5498</PDBx:U11>
         <PDBx:U12>0.0359</PDBx:U12>
         <PDBx:U13>0.0999</PDBx:U13>
         <PDBx:U22>0.8266</PDBx:U22>
         <PDBx:U23>-0.1033</PDBx:U23>
         <PDBx:U33>0.4882</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>639</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>263</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1983">
         <PDBx:U11>0.2946</PDBx:U11>
         <PDBx:U12>0.0180</PDBx:U12>
         <PDBx:U13>0.0393</PDBx:U13>
         <PDBx:U22>0.2624</PDBx:U22>
         <PDBx:U23>-0.0399</PDBx:U23>
         <PDBx:U33>0.2633</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>640</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1984">
         <PDBx:U11>0.2964</PDBx:U11>
         <PDBx:U12>0.0138</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.2623</PDBx:U22>
         <PDBx:U23>-0.0455</PDBx:U23>
         <PDBx:U33>0.3044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>640</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1985">
         <PDBx:U11>0.2775</PDBx:U11>
         <PDBx:U12>0.0210</PDBx:U12>
         <PDBx:U13>0.0164</PDBx:U13>
         <PDBx:U22>0.2102</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.2690</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>640</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1986">
         <PDBx:U11>0.2772</PDBx:U11>
         <PDBx:U12>0.0601</PDBx:U12>
         <PDBx:U13>-0.0164</PDBx:U13>
         <PDBx:U22>0.2594</PDBx:U22>
         <PDBx:U23>-0.0212</PDBx:U23>
         <PDBx:U33>0.2661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>640</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1987">
         <PDBx:U11>0.4054</PDBx:U11>
         <PDBx:U12>0.0187</PDBx:U12>
         <PDBx:U13>0.0917</PDBx:U13>
         <PDBx:U22>0.2230</PDBx:U22>
         <PDBx:U23>-0.0394</PDBx:U23>
         <PDBx:U33>0.3144</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>640</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1988">
         <PDBx:U11>0.4045</PDBx:U11>
         <PDBx:U12>0.1016</PDBx:U12>
         <PDBx:U13>0.0498</PDBx:U13>
         <PDBx:U22>0.3220</PDBx:U22>
         <PDBx:U23>-0.1072</PDBx:U23>
         <PDBx:U33>0.4221</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>640</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1989">
         <PDBx:U11>0.3972</PDBx:U11>
         <PDBx:U12>0.1150</PDBx:U12>
         <PDBx:U13>0.1231</PDBx:U13>
         <PDBx:U22>0.4273</PDBx:U22>
         <PDBx:U23>0.0161</PDBx:U23>
         <PDBx:U33>0.5926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>640</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1990">
         <PDBx:U11>1.1067</PDBx:U11>
         <PDBx:U12>-0.0434</PDBx:U12>
         <PDBx:U13>0.1611</PDBx:U13>
         <PDBx:U22>0.4970</PDBx:U22>
         <PDBx:U23>0.0960</PDBx:U23>
         <PDBx:U33>1.0219</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>640</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1991">
         <PDBx:U11>0.4696</PDBx:U11>
         <PDBx:U12>0.0463</PDBx:U12>
         <PDBx:U13>0.0271</PDBx:U13>
         <PDBx:U22>0.3850</PDBx:U22>
         <PDBx:U23>-0.0497</PDBx:U23>
         <PDBx:U33>0.7674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>640</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>264</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1992">
         <PDBx:U11>0.2243</PDBx:U11>
         <PDBx:U12>0.0186</PDBx:U12>
         <PDBx:U13>0.0345</PDBx:U13>
         <PDBx:U22>0.2073</PDBx:U22>
         <PDBx:U23>-0.0167</PDBx:U23>
         <PDBx:U33>0.2476</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>641</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1993">
         <PDBx:U11>0.2043</PDBx:U11>
         <PDBx:U12>0.0014</PDBx:U12>
         <PDBx:U13>0.0362</PDBx:U13>
         <PDBx:U22>0.1788</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.2316</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>641</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1994">
         <PDBx:U11>0.2080</PDBx:U11>
         <PDBx:U12>0.0081</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>0.2030</PDBx:U22>
         <PDBx:U23>-0.0104</PDBx:U23>
         <PDBx:U33>0.2146</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>641</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1995">
         <PDBx:U11>0.2191</PDBx:U11>
         <PDBx:U12>0.0046</PDBx:U12>
         <PDBx:U13>0.0284</PDBx:U13>
         <PDBx:U22>0.2349</PDBx:U22>
         <PDBx:U23>-0.0138</PDBx:U23>
         <PDBx:U33>0.2224</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>641</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1996">
         <PDBx:U11>0.1514</PDBx:U11>
         <PDBx:U12>0.0191</PDBx:U12>
         <PDBx:U13>0.0261</PDBx:U13>
         <PDBx:U22>0.2200</PDBx:U22>
         <PDBx:U23>-0.0092</PDBx:U23>
         <PDBx:U33>0.2446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>641</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1997">
         <PDBx:U11>0.1797</PDBx:U11>
         <PDBx:U12>0.0099</PDBx:U12>
         <PDBx:U13>0.0144</PDBx:U13>
         <PDBx:U22>0.1437</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.1975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>641</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1998">
         <PDBx:U11>0.1882</PDBx:U11>
         <PDBx:U12>0.0178</PDBx:U12>
         <PDBx:U13>-0.0095</PDBx:U13>
         <PDBx:U22>0.1889</PDBx:U22>
         <PDBx:U23>0.0232</PDBx:U23>
         <PDBx:U33>0.2266</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>641</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1999">
         <PDBx:U11>0.1813</PDBx:U11>
         <PDBx:U12>0.0128</PDBx:U12>
         <PDBx:U13>0.0056</PDBx:U13>
         <PDBx:U22>0.1994</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.1828</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>641</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2000">
         <PDBx:U11>0.1780</PDBx:U11>
         <PDBx:U12>0.0080</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.1878</PDBx:U22>
         <PDBx:U23>0.0166</PDBx:U23>
         <PDBx:U33>0.2036</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>641</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2001">
         <PDBx:U11>0.2209</PDBx:U11>
         <PDBx:U12>0.0147</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.1792</PDBx:U22>
         <PDBx:U23>-0.0075</PDBx:U23>
         <PDBx:U33>0.1812</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>641</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2002">
         <PDBx:U11>0.2122</PDBx:U11>
         <PDBx:U12>0.0054</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>0.2008</PDBx:U22>
         <PDBx:U23>-0.0121</PDBx:U23>
         <PDBx:U33>0.2090</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>641</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>265</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2003">
         <PDBx:U11>0.2034</PDBx:U11>
         <PDBx:U12>0.0010</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.2025</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.2180</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>642</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2004">
         <PDBx:U11>0.2058</PDBx:U11>
         <PDBx:U12>0.0095</PDBx:U12>
         <PDBx:U13>-0.0062</PDBx:U13>
         <PDBx:U22>0.1882</PDBx:U22>
         <PDBx:U23>-0.0107</PDBx:U23>
         <PDBx:U33>0.2009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>642</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2005">
         <PDBx:U11>0.1787</PDBx:U11>
         <PDBx:U12>0.0040</PDBx:U12>
         <PDBx:U13>0.0137</PDBx:U13>
         <PDBx:U22>0.2240</PDBx:U22>
         <PDBx:U23>0.0131</PDBx:U23>
         <PDBx:U33>0.2349</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>642</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2006">
         <PDBx:U11>0.2278</PDBx:U11>
         <PDBx:U12>0.0262</PDBx:U12>
         <PDBx:U13>0.0069</PDBx:U13>
         <PDBx:U22>0.1843</PDBx:U22>
         <PDBx:U23>0.0154</PDBx:U23>
         <PDBx:U33>0.2349</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>642</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2007">
         <PDBx:U11>0.1953</PDBx:U11>
         <PDBx:U12>0.0322</PDBx:U12>
         <PDBx:U13>0.0281</PDBx:U13>
         <PDBx:U22>0.2526</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.1920</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>642</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2008">
         <PDBx:U11>0.2037</PDBx:U11>
         <PDBx:U12>0.0148</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.2633</PDBx:U22>
         <PDBx:U23>-0.0383</PDBx:U23>
         <PDBx:U33>0.1843</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>642</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2009">
         <PDBx:U11>0.2173</PDBx:U11>
         <PDBx:U12>-0.0215</PDBx:U12>
         <PDBx:U13>0.0089</PDBx:U13>
         <PDBx:U22>0.2117</PDBx:U22>
         <PDBx:U23>-0.0060</PDBx:U23>
         <PDBx:U33>0.2182</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>642</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>266</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2010">
         <PDBx:U11>0.2073</PDBx:U11>
         <PDBx:U12>-0.0210</PDBx:U12>
         <PDBx:U13>0.0213</PDBx:U13>
         <PDBx:U22>0.1952</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.2117</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>643</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2011">
         <PDBx:U11>0.2077</PDBx:U11>
         <PDBx:U12>0.0000</PDBx:U12>
         <PDBx:U13>-0.0062</PDBx:U13>
         <PDBx:U22>0.1902</PDBx:U22>
         <PDBx:U23>0.0030</PDBx:U23>
         <PDBx:U33>0.2060</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>643</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2012">
         <PDBx:U11>0.2027</PDBx:U11>
         <PDBx:U12>0.0128</PDBx:U12>
         <PDBx:U13>0.0106</PDBx:U13>
         <PDBx:U22>0.1932</PDBx:U22>
         <PDBx:U23>0.0080</PDBx:U23>
         <PDBx:U33>0.1938</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>643</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2013">
         <PDBx:U11>0.2003</PDBx:U11>
         <PDBx:U12>0.0052</PDBx:U12>
         <PDBx:U13>-0.0073</PDBx:U13>
         <PDBx:U22>0.2051</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.2050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>643</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2014">
         <PDBx:U11>0.2027</PDBx:U11>
         <PDBx:U12>0.0407</PDBx:U12>
         <PDBx:U13>0.0278</PDBx:U13>
         <PDBx:U22>0.2685</PDBx:U22>
         <PDBx:U23>-0.0069</PDBx:U23>
         <PDBx:U33>0.2214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>643</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2015">
         <PDBx:U11>0.2224</PDBx:U11>
         <PDBx:U12>0.0023</PDBx:U12>
         <PDBx:U13>0.0122</PDBx:U13>
         <PDBx:U22>0.2402</PDBx:U22>
         <PDBx:U23>0.0146</PDBx:U23>
         <PDBx:U33>0.2369</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>643</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2016">
         <PDBx:U11>0.2413</PDBx:U11>
         <PDBx:U12>-0.0267</PDBx:U12>
         <PDBx:U13>0.0501</PDBx:U13>
         <PDBx:U22>0.2362</PDBx:U22>
         <PDBx:U23>-0.0318</PDBx:U23>
         <PDBx:U33>0.2506</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>643</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>267</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2017">
         <PDBx:U11>0.2102</PDBx:U11>
         <PDBx:U12>0.0052</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.1999</PDBx:U22>
         <PDBx:U23>-0.0164</PDBx:U23>
         <PDBx:U33>0.2111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>644</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2018">
         <PDBx:U11>0.2129</PDBx:U11>
         <PDBx:U12>0.0179</PDBx:U12>
         <PDBx:U13>-0.0353</PDBx:U13>
         <PDBx:U22>0.1696</PDBx:U22>
         <PDBx:U23>-0.0061</PDBx:U23>
         <PDBx:U33>0.1849</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>644</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2019">
         <PDBx:U11>0.1743</PDBx:U11>
         <PDBx:U12>0.0232</PDBx:U12>
         <PDBx:U13>0.0021</PDBx:U13>
         <PDBx:U22>0.2074</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.2152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>644</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2020">
         <PDBx:U11>0.1896</PDBx:U11>
         <PDBx:U12>0.0163</PDBx:U12>
         <PDBx:U13>0.0119</PDBx:U13>
         <PDBx:U22>0.2139</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.2099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>644</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2021">
         <PDBx:U11>0.1831</PDBx:U11>
         <PDBx:U12>0.0158</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.1692</PDBx:U22>
         <PDBx:U23>0.0163</PDBx:U23>
         <PDBx:U33>0.2147</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>644</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2022">
         <PDBx:U11>0.1776</PDBx:U11>
         <PDBx:U12>0.0062</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.2122</PDBx:U22>
         <PDBx:U23>0.0069</PDBx:U23>
         <PDBx:U33>0.2010</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>644</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2023">
         <PDBx:U11>0.1982</PDBx:U11>
         <PDBx:U12>0.0262</PDBx:U12>
         <PDBx:U13>0.0381</PDBx:U13>
         <PDBx:U22>0.2014</PDBx:U22>
         <PDBx:U23>0.0366</PDBx:U23>
         <PDBx:U33>0.2255</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>644</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2024">
         <PDBx:U11>0.2128</PDBx:U11>
         <PDBx:U12>0.0187</PDBx:U12>
         <PDBx:U13>0.0206</PDBx:U13>
         <PDBx:U22>0.2127</PDBx:U22>
         <PDBx:U23>0.0104</PDBx:U23>
         <PDBx:U33>0.1969</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>644</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2025">
         <PDBx:U11>0.1908</PDBx:U11>
         <PDBx:U12>0.0212</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.1881</PDBx:U22>
         <PDBx:U23>0.0019</PDBx:U23>
         <PDBx:U33>0.1791</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>644</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2026">
         <PDBx:U11>0.2018</PDBx:U11>
         <PDBx:U12>-0.0481</PDBx:U12>
         <PDBx:U13>0.0248</PDBx:U13>
         <PDBx:U22>0.2254</PDBx:U22>
         <PDBx:U23>0.0179</PDBx:U23>
         <PDBx:U33>0.1957</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>644</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2027">
         <PDBx:U11>0.1735</PDBx:U11>
         <PDBx:U12>-0.0301</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1678</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.1825</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>644</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>268</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2028">
         <PDBx:U11>0.1757</PDBx:U11>
         <PDBx:U12>0.0092</PDBx:U12>
         <PDBx:U13>0.0099</PDBx:U13>
         <PDBx:U22>0.2009</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.2363</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>645</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2029">
         <PDBx:U11>0.2013</PDBx:U11>
         <PDBx:U12>0.0198</PDBx:U12>
         <PDBx:U13>0.0096</PDBx:U13>
         <PDBx:U22>0.2237</PDBx:U22>
         <PDBx:U23>0.0089</PDBx:U23>
         <PDBx:U33>0.1997</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>645</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2030">
         <PDBx:U11>0.2027</PDBx:U11>
         <PDBx:U12>0.0155</PDBx:U12>
         <PDBx:U13>-0.0199</PDBx:U13>
         <PDBx:U22>0.2103</PDBx:U22>
         <PDBx:U23>0.0112</PDBx:U23>
         <PDBx:U33>0.2407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>645</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2031">
         <PDBx:U11>0.2191</PDBx:U11>
         <PDBx:U12>0.0509</PDBx:U12>
         <PDBx:U13>-0.0034</PDBx:U13>
         <PDBx:U22>0.2536</PDBx:U22>
         <PDBx:U23>-0.0155</PDBx:U23>
         <PDBx:U33>0.2535</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>645</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2032">
         <PDBx:U11>0.1735</PDBx:U11>
         <PDBx:U12>-0.0067</PDBx:U12>
         <PDBx:U13>0.0289</PDBx:U13>
         <PDBx:U22>0.2799</PDBx:U22>
         <PDBx:U23>0.0147</PDBx:U23>
         <PDBx:U33>0.2928</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>645</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2033">
         <PDBx:U11>0.2209</PDBx:U11>
         <PDBx:U12>0.0183</PDBx:U12>
         <PDBx:U13>-0.0274</PDBx:U13>
         <PDBx:U22>0.3830</PDBx:U22>
         <PDBx:U23>0.0510</PDBx:U23>
         <PDBx:U33>0.3547</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>645</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2034">
         <PDBx:U11>0.4663</PDBx:U11>
         <PDBx:U12>-0.0196</PDBx:U12>
         <PDBx:U13>0.1327</PDBx:U13>
         <PDBx:U22>0.4809</PDBx:U22>
         <PDBx:U23>0.0928</PDBx:U23>
         <PDBx:U33>0.4174</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>645</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2035">
         <PDBx:U11>0.6330</PDBx:U11>
         <PDBx:U12>-0.0092</PDBx:U12>
         <PDBx:U13>-0.0701</PDBx:U13>
         <PDBx:U22>0.5383</PDBx:U22>
         <PDBx:U23>0.1295</PDBx:U23>
         <PDBx:U33>0.5337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>645</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2036">
         <PDBx:U11>0.6938</PDBx:U11>
         <PDBx:U12>-0.0683</PDBx:U12>
         <PDBx:U13>-0.1114</PDBx:U13>
         <PDBx:U22>0.8280</PDBx:U22>
         <PDBx:U23>-0.1383</PDBx:U23>
         <PDBx:U33>0.7143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>645</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>269</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2037">
         <PDBx:U11>0.1903</PDBx:U11>
         <PDBx:U12>0.0040</PDBx:U12>
         <PDBx:U13>0.0186</PDBx:U13>
         <PDBx:U22>0.1921</PDBx:U22>
         <PDBx:U23>0.0064</PDBx:U23>
         <PDBx:U33>0.2269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>646</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2038">
         <PDBx:U11>0.1847</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>0.0129</PDBx:U13>
         <PDBx:U22>0.1988</PDBx:U22>
         <PDBx:U23>0.0065</PDBx:U23>
         <PDBx:U33>0.2155</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>646</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2039">
         <PDBx:U11>0.2147</PDBx:U11>
         <PDBx:U12>0.0260</PDBx:U12>
         <PDBx:U13>0.0170</PDBx:U13>
         <PDBx:U22>0.2043</PDBx:U22>
         <PDBx:U23>0.0250</PDBx:U23>
         <PDBx:U33>0.2205</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>646</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2040">
         <PDBx:U11>0.2415</PDBx:U11>
         <PDBx:U12>0.0166</PDBx:U12>
         <PDBx:U13>-0.0128</PDBx:U13>
         <PDBx:U22>0.2262</PDBx:U22>
         <PDBx:U23>0.0137</PDBx:U23>
         <PDBx:U33>0.2237</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>646</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2041">
         <PDBx:U11>0.2487</PDBx:U11>
         <PDBx:U12>0.0057</PDBx:U12>
         <PDBx:U13>0.0296</PDBx:U13>
         <PDBx:U22>0.2196</PDBx:U22>
         <PDBx:U23>-0.0244</PDBx:U23>
         <PDBx:U33>0.2507</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>646</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2042">
         <PDBx:U11>0.2737</PDBx:U11>
         <PDBx:U12>0.0672</PDBx:U12>
         <PDBx:U13>0.0222</PDBx:U13>
         <PDBx:U22>0.2469</PDBx:U22>
         <PDBx:U23>-0.0228</PDBx:U23>
         <PDBx:U33>0.2267</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>646</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2043">
         <PDBx:U11>0.2250</PDBx:U11>
         <PDBx:U12>0.0183</PDBx:U12>
         <PDBx:U13>-0.0095</PDBx:U13>
         <PDBx:U22>0.2353</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.2168</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>646</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2044">
         <PDBx:U11>0.3492</PDBx:U11>
         <PDBx:U12>0.0431</PDBx:U12>
         <PDBx:U13>0.0146</PDBx:U13>
         <PDBx:U22>0.2586</PDBx:U22>
         <PDBx:U23>-0.0384</PDBx:U23>
         <PDBx:U33>0.2224</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>646</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>270</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2045">
         <PDBx:U11>0.1934</PDBx:U11>
         <PDBx:U12>0.0152</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.2282</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.2062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>647</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2046">
         <PDBx:U11>0.1471</PDBx:U11>
         <PDBx:U12>0.0343</PDBx:U12>
         <PDBx:U13>-0.0154</PDBx:U13>
         <PDBx:U22>0.2241</PDBx:U22>
         <PDBx:U23>0.0083</PDBx:U23>
         <PDBx:U33>0.2173</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>647</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2047">
         <PDBx:U11>0.1840</PDBx:U11>
         <PDBx:U12>0.0080</PDBx:U12>
         <PDBx:U13>0.0112</PDBx:U13>
         <PDBx:U22>0.2219</PDBx:U22>
         <PDBx:U23>0.0069</PDBx:U23>
         <PDBx:U33>0.2030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>647</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2048">
         <PDBx:U11>0.2087</PDBx:U11>
         <PDBx:U12>0.0181</PDBx:U12>
         <PDBx:U13>-0.0148</PDBx:U13>
         <PDBx:U22>0.1942</PDBx:U22>
         <PDBx:U23>0.0233</PDBx:U23>
         <PDBx:U33>0.2077</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>647</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2049">
         <PDBx:U11>0.1455</PDBx:U11>
         <PDBx:U12>0.0187</PDBx:U12>
         <PDBx:U13>-0.0176</PDBx:U13>
         <PDBx:U22>0.1810</PDBx:U22>
         <PDBx:U23>-0.0094</PDBx:U23>
         <PDBx:U33>0.1899</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>647</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2050">
         <PDBx:U11>0.1734</PDBx:U11>
         <PDBx:U12>-0.0142</PDBx:U12>
         <PDBx:U13>-0.0131</PDBx:U13>
         <PDBx:U22>0.1697</PDBx:U22>
         <PDBx:U23>0.0034</PDBx:U23>
         <PDBx:U33>0.2071</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>647</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2051">
         <PDBx:U11>0.1901</PDBx:U11>
         <PDBx:U12>0.0100</PDBx:U12>
         <PDBx:U13>-0.0034</PDBx:U13>
         <PDBx:U22>0.2224</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.1814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>647</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2052">
         <PDBx:U11>0.2271</PDBx:U11>
         <PDBx:U12>0.0119</PDBx:U12>
         <PDBx:U13>0.0146</PDBx:U13>
         <PDBx:U22>0.1954</PDBx:U22>
         <PDBx:U23>0.0340</PDBx:U23>
         <PDBx:U33>0.2098</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>647</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>271</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2053">
         <PDBx:U11>0.1414</PDBx:U11>
         <PDBx:U12>0.0191</PDBx:U12>
         <PDBx:U13>-0.0131</PDBx:U13>
         <PDBx:U22>0.1860</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.2112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>648</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2054">
         <PDBx:U11>0.1987</PDBx:U11>
         <PDBx:U12>0.0214</PDBx:U12>
         <PDBx:U13>-0.0189</PDBx:U13>
         <PDBx:U22>0.1749</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.2104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>648</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2055">
         <PDBx:U11>0.1900</PDBx:U11>
         <PDBx:U12>0.0122</PDBx:U12>
         <PDBx:U13>-0.0094</PDBx:U13>
         <PDBx:U22>0.1964</PDBx:U22>
         <PDBx:U23>0.0123</PDBx:U23>
         <PDBx:U33>0.2162</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>648</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2056">
         <PDBx:U11>0.2191</PDBx:U11>
         <PDBx:U12>0.0127</PDBx:U12>
         <PDBx:U13>-0.0346</PDBx:U13>
         <PDBx:U22>0.2140</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.2410</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>648</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2057">
         <PDBx:U11>0.2058</PDBx:U11>
         <PDBx:U12>-0.0007</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.2069</PDBx:U22>
         <PDBx:U23>0.0118</PDBx:U23>
         <PDBx:U33>0.2123</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>648</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2058">
         <PDBx:U11>0.2108</PDBx:U11>
         <PDBx:U12>-0.0173</PDBx:U12>
         <PDBx:U13>0.0323</PDBx:U13>
         <PDBx:U22>0.2236</PDBx:U22>
         <PDBx:U23>-0.0122</PDBx:U23>
         <PDBx:U33>0.2246</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>648</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2059">
         <PDBx:U11>0.2555</PDBx:U11>
         <PDBx:U12>0.0176</PDBx:U12>
         <PDBx:U13>0.0585</PDBx:U13>
         <PDBx:U22>0.2328</PDBx:U22>
         <PDBx:U23>0.0269</PDBx:U23>
         <PDBx:U33>0.2323</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>648</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2060">
         <PDBx:U11>0.2576</PDBx:U11>
         <PDBx:U12>-0.0849</PDBx:U12>
         <PDBx:U13>0.0573</PDBx:U13>
         <PDBx:U22>0.2297</PDBx:U22>
         <PDBx:U23>-0.0575</PDBx:U23>
         <PDBx:U33>0.3110</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>648</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>272</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2061">
         <PDBx:U11>0.1837</PDBx:U11>
         <PDBx:U12>0.0178</PDBx:U12>
         <PDBx:U13>-0.0220</PDBx:U13>
         <PDBx:U22>0.2175</PDBx:U22>
         <PDBx:U23>-0.0211</PDBx:U23>
         <PDBx:U33>0.2383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>649</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2062">
         <PDBx:U11>0.1991</PDBx:U11>
         <PDBx:U12>0.0167</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.1944</PDBx:U22>
         <PDBx:U23>0.0127</PDBx:U23>
         <PDBx:U33>0.2336</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>649</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2063">
         <PDBx:U11>0.2056</PDBx:U11>
         <PDBx:U12>0.0088</PDBx:U12>
         <PDBx:U13>-0.0054</PDBx:U13>
         <PDBx:U22>0.2401</PDBx:U22>
         <PDBx:U23>0.0254</PDBx:U23>
         <PDBx:U33>0.2569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>649</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2064">
         <PDBx:U11>0.2180</PDBx:U11>
         <PDBx:U12>0.0399</PDBx:U12>
         <PDBx:U13>-0.0088</PDBx:U13>
         <PDBx:U22>0.2420</PDBx:U22>
         <PDBx:U23>0.0024</PDBx:U23>
         <PDBx:U33>0.2648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>649</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2065">
         <PDBx:U11>0.2790</PDBx:U11>
         <PDBx:U12>0.0109</PDBx:U12>
         <PDBx:U13>0.0484</PDBx:U13>
         <PDBx:U22>0.3235</PDBx:U22>
         <PDBx:U23>-0.0334</PDBx:U23>
         <PDBx:U33>0.2264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>649</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2066">
         <PDBx:U11>0.4169</PDBx:U11>
         <PDBx:U12>0.0333</PDBx:U12>
         <PDBx:U13>-0.0223</PDBx:U13>
         <PDBx:U22>0.4231</PDBx:U22>
         <PDBx:U23>0.0134</PDBx:U23>
         <PDBx:U33>0.4268</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>649</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>273</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2067">
         <PDBx:U11>0.2069</PDBx:U11>
         <PDBx:U12>0.0096</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.1754</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.2363</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>650</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2068">
         <PDBx:U11>0.1999</PDBx:U11>
         <PDBx:U12>-0.0186</PDBx:U12>
         <PDBx:U13>0.0150</PDBx:U13>
         <PDBx:U22>0.2080</PDBx:U22>
         <PDBx:U23>0.0040</PDBx:U23>
         <PDBx:U33>0.2328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>650</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2069">
         <PDBx:U11>0.1947</PDBx:U11>
         <PDBx:U12>0.0110</PDBx:U12>
         <PDBx:U13>-0.0152</PDBx:U13>
         <PDBx:U22>0.2067</PDBx:U22>
         <PDBx:U23>0.0116</PDBx:U23>
         <PDBx:U33>0.2210</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>650</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2070">
         <PDBx:U11>0.1864</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>-0.0229</PDBx:U13>
         <PDBx:U22>0.2650</PDBx:U22>
         <PDBx:U23>0.0047</PDBx:U23>
         <PDBx:U33>0.2136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>650</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2071">
         <PDBx:U11>0.2265</PDBx:U11>
         <PDBx:U12>-0.0061</PDBx:U12>
         <PDBx:U13>-0.0340</PDBx:U13>
         <PDBx:U22>0.2439</PDBx:U22>
         <PDBx:U23>-0.0081</PDBx:U23>
         <PDBx:U33>0.2372</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>650</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2072">
         <PDBx:U11>0.2621</PDBx:U11>
         <PDBx:U12>-0.0150</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.2999</PDBx:U22>
         <PDBx:U23>-0.0187</PDBx:U23>
         <PDBx:U33>0.3064</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>650</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2073">
         <PDBx:U11>0.4015</PDBx:U11>
         <PDBx:U12>0.0608</PDBx:U12>
         <PDBx:U13>0.0612</PDBx:U13>
         <PDBx:U22>0.2549</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.3882</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>650</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2074">
         <PDBx:U11>0.3768</PDBx:U11>
         <PDBx:U12>-0.0398</PDBx:U12>
         <PDBx:U13>-0.0465</PDBx:U13>
         <PDBx:U22>0.3603</PDBx:U22>
         <PDBx:U23>-0.0270</PDBx:U23>
         <PDBx:U33>0.3007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>650</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>274</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2075">
         <PDBx:U11>0.1791</PDBx:U11>
         <PDBx:U12>0.0166</PDBx:U12>
         <PDBx:U13>-0.0287</PDBx:U13>
         <PDBx:U22>0.1926</PDBx:U22>
         <PDBx:U23>-0.0289</PDBx:U23>
         <PDBx:U33>0.2133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>651</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2076">
         <PDBx:U11>0.1954</PDBx:U11>
         <PDBx:U12>0.0099</PDBx:U12>
         <PDBx:U13>-0.0088</PDBx:U13>
         <PDBx:U22>0.1806</PDBx:U22>
         <PDBx:U23>0.0044</PDBx:U23>
         <PDBx:U33>0.2094</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>651</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2077">
         <PDBx:U11>0.2030</PDBx:U11>
         <PDBx:U12>-0.0018</PDBx:U12>
         <PDBx:U13>0.0114</PDBx:U13>
         <PDBx:U22>0.2184</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.2138</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>651</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2078">
         <PDBx:U11>0.2048</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>-0.0075</PDBx:U13>
         <PDBx:U22>0.2123</PDBx:U22>
         <PDBx:U23>0.0262</PDBx:U23>
         <PDBx:U33>0.2058</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>651</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2079">
         <PDBx:U11>0.1641</PDBx:U11>
         <PDBx:U12>-0.0004</PDBx:U12>
         <PDBx:U13>-0.0088</PDBx:U13>
         <PDBx:U22>0.1725</PDBx:U22>
         <PDBx:U23>-0.0166</PDBx:U23>
         <PDBx:U33>0.1921</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>651</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2080">
         <PDBx:U11>0.1631</PDBx:U11>
         <PDBx:U12>-0.0049</PDBx:U12>
         <PDBx:U13>-0.0249</PDBx:U13>
         <PDBx:U22>0.1901</PDBx:U22>
         <PDBx:U23>0.0439</PDBx:U23>
         <PDBx:U33>0.1697</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>651</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2081">
         <PDBx:U11>0.2372</PDBx:U11>
         <PDBx:U12>-0.0100</PDBx:U12>
         <PDBx:U13>-0.0081</PDBx:U13>
         <PDBx:U22>0.2010</PDBx:U22>
         <PDBx:U23>-0.0450</PDBx:U23>
         <PDBx:U33>0.2230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>651</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2082">
         <PDBx:U11>0.2063</PDBx:U11>
         <PDBx:U12>0.0372</PDBx:U12>
         <PDBx:U13>-0.0359</PDBx:U13>
         <PDBx:U22>0.1772</PDBx:U22>
         <PDBx:U23>0.0461</PDBx:U23>
         <PDBx:U33>0.2409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>651</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>275</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2083">
         <PDBx:U11>0.1895</PDBx:U11>
         <PDBx:U12>-0.0328</PDBx:U12>
         <PDBx:U13>-0.0230</PDBx:U13>
         <PDBx:U22>0.2420</PDBx:U22>
         <PDBx:U23>0.0071</PDBx:U23>
         <PDBx:U33>0.1904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>652</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2084">
         <PDBx:U11>0.1770</PDBx:U11>
         <PDBx:U12>-0.0269</PDBx:U12>
         <PDBx:U13>-0.0348</PDBx:U13>
         <PDBx:U22>0.2557</PDBx:U22>
         <PDBx:U23>0.0187</PDBx:U23>
         <PDBx:U33>0.2286</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>652</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2085">
         <PDBx:U11>0.1839</PDBx:U11>
         <PDBx:U12>0.0028</PDBx:U12>
         <PDBx:U13>-0.0261</PDBx:U13>
         <PDBx:U22>0.2375</PDBx:U22>
         <PDBx:U23>0.0043</PDBx:U23>
         <PDBx:U33>0.2460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>652</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2086">
         <PDBx:U11>0.1944</PDBx:U11>
         <PDBx:U12>-0.0131</PDBx:U12>
         <PDBx:U13>-0.0155</PDBx:U13>
         <PDBx:U22>0.2748</PDBx:U22>
         <PDBx:U23>0.0173</PDBx:U23>
         <PDBx:U33>0.2299</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>652</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2087">
         <PDBx:U11>0.2592</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>0.0415</PDBx:U13>
         <PDBx:U22>0.2224</PDBx:U22>
         <PDBx:U23>0.0150</PDBx:U23>
         <PDBx:U33>0.2511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>652</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2088">
         <PDBx:U11>0.2582</PDBx:U11>
         <PDBx:U12>-0.0313</PDBx:U12>
         <PDBx:U13>0.0435</PDBx:U13>
         <PDBx:U22>0.2227</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.2536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>652</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2089">
         <PDBx:U11>0.2273</PDBx:U11>
         <PDBx:U12>-0.0340</PDBx:U12>
         <PDBx:U13>0.0405</PDBx:U13>
         <PDBx:U22>0.2701</PDBx:U22>
         <PDBx:U23>-0.0144</PDBx:U23>
         <PDBx:U33>0.2507</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>652</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2090">
         <PDBx:U11>0.2556</PDBx:U11>
         <PDBx:U12>-0.0500</PDBx:U12>
         <PDBx:U13>-0.0046</PDBx:U13>
         <PDBx:U22>0.2832</PDBx:U22>
         <PDBx:U23>-0.0349</PDBx:U23>
         <PDBx:U33>0.2397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>652</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>276</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2091">
         <PDBx:U11>0.2009</PDBx:U11>
         <PDBx:U12>0.0335</PDBx:U12>
         <PDBx:U13>-0.0141</PDBx:U13>
         <PDBx:U22>0.2393</PDBx:U22>
         <PDBx:U23>0.0060</PDBx:U23>
         <PDBx:U33>0.2488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>653</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2092">
         <PDBx:U11>0.2537</PDBx:U11>
         <PDBx:U12>0.0342</PDBx:U12>
         <PDBx:U13>-0.0455</PDBx:U13>
         <PDBx:U22>0.2558</PDBx:U22>
         <PDBx:U23>0.0180</PDBx:U23>
         <PDBx:U33>0.2355</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>653</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2093">
         <PDBx:U11>0.2336</PDBx:U11>
         <PDBx:U12>-0.0009</PDBx:U12>
         <PDBx:U13>-0.0427</PDBx:U13>
         <PDBx:U22>0.2921</PDBx:U22>
         <PDBx:U23>0.0335</PDBx:U23>
         <PDBx:U33>0.2865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>653</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2094">
         <PDBx:U11>0.2433</PDBx:U11>
         <PDBx:U12>0.0190</PDBx:U12>
         <PDBx:U13>-0.0150</PDBx:U13>
         <PDBx:U22>0.2912</PDBx:U22>
         <PDBx:U23>0.0402</PDBx:U23>
         <PDBx:U33>0.2439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>653</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2095">
         <PDBx:U11>0.2849</PDBx:U11>
         <PDBx:U12>0.0912</PDBx:U12>
         <PDBx:U13>-0.0450</PDBx:U13>
         <PDBx:U22>0.2548</PDBx:U22>
         <PDBx:U23>0.0306</PDBx:U23>
         <PDBx:U33>0.3015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>653</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2096">
         <PDBx:U11>0.3717</PDBx:U11>
         <PDBx:U12>0.0328</PDBx:U12>
         <PDBx:U13>0.0236</PDBx:U13>
         <PDBx:U22>0.3488</PDBx:U22>
         <PDBx:U23>-0.0297</PDBx:U23>
         <PDBx:U33>0.4086</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>653</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2097">
         <PDBx:U11>0.6047</PDBx:U11>
         <PDBx:U12>0.1643</PDBx:U12>
         <PDBx:U13>0.0010</PDBx:U13>
         <PDBx:U22>0.4162</PDBx:U22>
         <PDBx:U23>-0.0257</PDBx:U23>
         <PDBx:U33>0.4692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>653</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2098">
         <PDBx:U11>0.3359</PDBx:U11>
         <PDBx:U12>0.0516</PDBx:U12>
         <PDBx:U13>0.0213</PDBx:U13>
         <PDBx:U22>0.4798</PDBx:U22>
         <PDBx:U23>-0.0389</PDBx:U23>
         <PDBx:U33>0.4368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>653</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>277</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2099">
         <PDBx:U11>0.2198</PDBx:U11>
         <PDBx:U12>0.0208</PDBx:U12>
         <PDBx:U13>-0.0205</PDBx:U13>
         <PDBx:U22>0.2275</PDBx:U22>
         <PDBx:U23>-0.0003</PDBx:U23>
         <PDBx:U33>0.2536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>654</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2100">
         <PDBx:U11>0.2199</PDBx:U11>
         <PDBx:U12>0.0083</PDBx:U12>
         <PDBx:U13>-0.0507</PDBx:U13>
         <PDBx:U22>0.2470</PDBx:U22>
         <PDBx:U23>0.0414</PDBx:U23>
         <PDBx:U33>0.2596</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>654</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2101">
         <PDBx:U11>0.2474</PDBx:U11>
         <PDBx:U12>-0.0017</PDBx:U12>
         <PDBx:U13>-0.0059</PDBx:U13>
         <PDBx:U22>0.2828</PDBx:U22>
         <PDBx:U23>0.0341</PDBx:U23>
         <PDBx:U33>0.2641</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>654</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2102">
         <PDBx:U11>0.2509</PDBx:U11>
         <PDBx:U12>0.0034</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.2800</PDBx:U22>
         <PDBx:U23>0.0419</PDBx:U23>
         <PDBx:U33>0.2519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>654</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2103">
         <PDBx:U11>0.2186</PDBx:U11>
         <PDBx:U12>0.0018</PDBx:U12>
         <PDBx:U13>-0.0489</PDBx:U13>
         <PDBx:U22>0.2419</PDBx:U22>
         <PDBx:U23>0.0338</PDBx:U23>
         <PDBx:U33>0.3132</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>654</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2104">
         <PDBx:U11>0.2227</PDBx:U11>
         <PDBx:U12>-0.0125</PDBx:U12>
         <PDBx:U13>-0.0325</PDBx:U13>
         <PDBx:U22>0.2659</PDBx:U22>
         <PDBx:U23>0.0479</PDBx:U23>
         <PDBx:U33>0.3392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>654</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2105">
         <PDBx:U11>0.2813</PDBx:U11>
         <PDBx:U12>-0.0349</PDBx:U12>
         <PDBx:U13>-0.0309</PDBx:U13>
         <PDBx:U22>0.2755</PDBx:U22>
         <PDBx:U23>0.0103</PDBx:U23>
         <PDBx:U33>0.2926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>654</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>278</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2106">
         <PDBx:U11>0.2130</PDBx:U11>
         <PDBx:U12>0.0276</PDBx:U12>
         <PDBx:U13>-0.0072</PDBx:U13>
         <PDBx:U22>0.2368</PDBx:U22>
         <PDBx:U23>0.0092</PDBx:U23>
         <PDBx:U33>0.2364</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>655</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2107">
         <PDBx:U11>0.2442</PDBx:U11>
         <PDBx:U12>-0.0489</PDBx:U12>
         <PDBx:U13>-0.0351</PDBx:U13>
         <PDBx:U22>0.2782</PDBx:U22>
         <PDBx:U23>0.0317</PDBx:U23>
         <PDBx:U33>0.2333</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>655</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2108">
         <PDBx:U11>0.2684</PDBx:U11>
         <PDBx:U12>0.0426</PDBx:U12>
         <PDBx:U13>-0.0316</PDBx:U13>
         <PDBx:U22>0.2834</PDBx:U22>
         <PDBx:U23>0.0166</PDBx:U23>
         <PDBx:U33>0.2589</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>655</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2109">
         <PDBx:U11>0.2604</PDBx:U11>
         <PDBx:U12>-0.0088</PDBx:U12>
         <PDBx:U13>-0.0061</PDBx:U13>
         <PDBx:U22>0.3542</PDBx:U22>
         <PDBx:U23>0.0031</PDBx:U23>
         <PDBx:U33>0.2664</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>655</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2110">
         <PDBx:U11>0.2723</PDBx:U11>
         <PDBx:U12>-0.0604</PDBx:U12>
         <PDBx:U13>-0.0360</PDBx:U13>
         <PDBx:U22>0.2862</PDBx:U22>
         <PDBx:U23>0.0370</PDBx:U23>
         <PDBx:U33>0.2595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>655</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2111">
         <PDBx:U11>0.2664</PDBx:U11>
         <PDBx:U12>-0.0355</PDBx:U12>
         <PDBx:U13>0.0265</PDBx:U13>
         <PDBx:U22>0.2907</PDBx:U22>
         <PDBx:U23>0.0642</PDBx:U23>
         <PDBx:U33>0.2935</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>655</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2112">
         <PDBx:U11>0.3411</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>0.0401</PDBx:U13>
         <PDBx:U22>0.3300</PDBx:U22>
         <PDBx:U23>0.0485</PDBx:U23>
         <PDBx:U33>0.4250</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>655</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2113">
         <PDBx:U11>0.3334</PDBx:U11>
         <PDBx:U12>0.0362</PDBx:U12>
         <PDBx:U13>-0.0860</PDBx:U13>
         <PDBx:U22>0.3299</PDBx:U22>
         <PDBx:U23>0.0941</PDBx:U23>
         <PDBx:U33>0.5616</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>655</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>279</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2114">
         <PDBx:U11>0.2202</PDBx:U11>
         <PDBx:U12>-0.0194</PDBx:U12>
         <PDBx:U13>-0.0205</PDBx:U13>
         <PDBx:U22>0.2498</PDBx:U22>
         <PDBx:U23>0.0181</PDBx:U23>
         <PDBx:U33>0.2475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>656</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2115">
         <PDBx:U11>0.2567</PDBx:U11>
         <PDBx:U12>0.0076</PDBx:U12>
         <PDBx:U13>-0.0325</PDBx:U13>
         <PDBx:U22>0.3019</PDBx:U22>
         <PDBx:U23>0.0323</PDBx:U23>
         <PDBx:U33>0.2401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>656</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2116">
         <PDBx:U11>0.2510</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.3171</PDBx:U22>
         <PDBx:U23>0.0286</PDBx:U23>
         <PDBx:U33>0.2625</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>656</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2117">
         <PDBx:U11>0.2734</PDBx:U11>
         <PDBx:U12>-0.0260</PDBx:U12>
         <PDBx:U13>-0.0211</PDBx:U13>
         <PDBx:U22>0.3593</PDBx:U22>
         <PDBx:U23>0.0776</PDBx:U23>
         <PDBx:U33>0.2822</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>656</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2118">
         <PDBx:U11>0.2441</PDBx:U11>
         <PDBx:U12>-0.0126</PDBx:U12>
         <PDBx:U13>-0.0179</PDBx:U13>
         <PDBx:U22>0.2648</PDBx:U22>
         <PDBx:U23>0.0116</PDBx:U23>
         <PDBx:U33>0.2878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>656</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2119">
         <PDBx:U11>0.2365</PDBx:U11>
         <PDBx:U12>-0.0021</PDBx:U12>
         <PDBx:U13>-0.0204</PDBx:U13>
         <PDBx:U22>0.3107</PDBx:U22>
         <PDBx:U23>0.0298</PDBx:U23>
         <PDBx:U33>0.3097</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>656</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2120">
         <PDBx:U11>0.2709</PDBx:U11>
         <PDBx:U12>-0.0779</PDBx:U12>
         <PDBx:U13>0.0227</PDBx:U13>
         <PDBx:U22>0.3321</PDBx:U22>
         <PDBx:U23>0.0635</PDBx:U23>
         <PDBx:U33>0.2899</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>656</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2121">
         <PDBx:U11>0.2575</PDBx:U11>
         <PDBx:U12>-0.0227</PDBx:U12>
         <PDBx:U13>-0.0363</PDBx:U13>
         <PDBx:U22>0.3243</PDBx:U22>
         <PDBx:U23>0.0328</PDBx:U23>
         <PDBx:U33>0.2600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>656</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>280</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2122">
         <PDBx:U11>0.2692</PDBx:U11>
         <PDBx:U12>-0.0210</PDBx:U12>
         <PDBx:U13>-0.0469</PDBx:U13>
         <PDBx:U22>0.3165</PDBx:U22>
         <PDBx:U23>0.0506</PDBx:U23>
         <PDBx:U33>0.3076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>657</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2123">
         <PDBx:U11>0.2778</PDBx:U11>
         <PDBx:U12>-0.0009</PDBx:U12>
         <PDBx:U13>-0.0435</PDBx:U13>
         <PDBx:U22>0.3501</PDBx:U22>
         <PDBx:U23>0.0729</PDBx:U23>
         <PDBx:U33>0.2957</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>657</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2124">
         <PDBx:U11>0.3029</PDBx:U11>
         <PDBx:U12>-0.0564</PDBx:U12>
         <PDBx:U13>-0.0322</PDBx:U13>
         <PDBx:U22>0.3844</PDBx:U22>
         <PDBx:U23>0.0465</PDBx:U23>
         <PDBx:U33>0.3254</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>657</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2125">
         <PDBx:U11>0.3978</PDBx:U11>
         <PDBx:U12>-0.0545</PDBx:U12>
         <PDBx:U13>-0.0200</PDBx:U13>
         <PDBx:U22>0.5232</PDBx:U22>
         <PDBx:U23>0.1011</PDBx:U23>
         <PDBx:U33>0.3222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>657</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2126">
         <PDBx:U11>0.3937</PDBx:U11>
         <PDBx:U12>-0.0240</PDBx:U12>
         <PDBx:U13>-0.0831</PDBx:U13>
         <PDBx:U22>0.3446</PDBx:U22>
         <PDBx:U23>0.0241</PDBx:U23>
         <PDBx:U33>0.3700</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>657</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2127">
         <PDBx:U11>0.7064</PDBx:U11>
         <PDBx:U12>-0.1404</PDBx:U12>
         <PDBx:U13>-0.0167</PDBx:U13>
         <PDBx:U22>0.5471</PDBx:U22>
         <PDBx:U23>0.0772</PDBx:U23>
         <PDBx:U33>0.4821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>657</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2128">
         <PDBx:U11>0.6486</PDBx:U11>
         <PDBx:U12>0.0408</PDBx:U12>
         <PDBx:U13>-0.0769</PDBx:U13>
         <PDBx:U22>0.3163</PDBx:U22>
         <PDBx:U23>-0.0939</PDBx:U23>
         <PDBx:U33>0.8858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>657</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2129">
         <PDBx:U11>0.4721</PDBx:U11>
         <PDBx:U12>0.1865</PDBx:U12>
         <PDBx:U13>0.0844</PDBx:U13>
         <PDBx:U22>1.0015</PDBx:U22>
         <PDBx:U23>-0.0411</PDBx:U23>
         <PDBx:U33>0.9291</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>657</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>281</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2130">
         <PDBx:U11>0.9070</PDBx:U11>
         <PDBx:U12>0.3055</PDBx:U12>
         <PDBx:U13>-0.0052</PDBx:U13>
         <PDBx:U22>0.6299</PDBx:U22>
         <PDBx:U23>-0.0378</PDBx:U23>
         <PDBx:U33>1.4376</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>657</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N28</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>481</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.5662</PDBx:U11>
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         <PDBx:U13>0.0015</PDBx:U13>
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         <PDBx:U23>0.0051</PDBx:U23>
         <PDBx:U33>0.6405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C44</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>481</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>701</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C44</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>481</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2182">
         <PDBx:U11>0.5467</PDBx:U11>
         <PDBx:U12>0.1227</PDBx:U12>
         <PDBx:U13>0.0365</PDBx:U13>
         <PDBx:U22>0.4835</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.3439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C27</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>481</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>701</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C27</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>481</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.3289</PDBx:U11>
         <PDBx:U12>0.0856</PDBx:U12>
         <PDBx:U13>0.0430</PDBx:U13>
         <PDBx:U22>0.6796</PDBx:U22>
         <PDBx:U23>-0.0575</PDBx:U23>
         <PDBx:U33>0.3652</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C26</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>481</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>701</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C26</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>481</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2957</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>0.0217</PDBx:U13>
         <PDBx:U22>0.2794</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.2808</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>S</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>DMS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>702</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>S</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>DMS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2185">
         <PDBx:U11>0.2657</PDBx:U11>
         <PDBx:U12>0.0145</PDBx:U12>
         <PDBx:U13>0.0132</PDBx:U13>
         <PDBx:U22>0.3466</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.3668</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>DMS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>702</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>DMS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2186">
         <PDBx:U11>0.4201</PDBx:U11>
         <PDBx:U12>-0.0564</PDBx:U12>
         <PDBx:U13>-0.0532</PDBx:U13>
         <PDBx:U22>0.3495</PDBx:U22>
         <PDBx:U23>0.0119</PDBx:U23>
         <PDBx:U33>0.2352</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>DMS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>702</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>DMS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.3419</PDBx:U11>
         <PDBx:U12>0.0076</PDBx:U12>
         <PDBx:U13>0.0760</PDBx:U13>
         <PDBx:U22>0.3077</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.1836</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>DMS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>702</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>DMS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2188">
         <PDBx:U11>0.5127</PDBx:U11>
         <PDBx:U12>-0.0393</PDBx:U12>
         <PDBx:U13>0.0285</PDBx:U13>
         <PDBx:U22>0.5099</PDBx:U22>
         <PDBx:U23>-0.0358</PDBx:U23>
         <PDBx:U33>0.5235</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>S</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>DMS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>703</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>S</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>DMS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2189">
         <PDBx:U11>0.4557</PDBx:U11>
         <PDBx:U12>0.0005</PDBx:U12>
         <PDBx:U13>0.1313</PDBx:U13>
         <PDBx:U22>0.4664</PDBx:U22>
         <PDBx:U23>-0.0378</PDBx:U23>
         <PDBx:U33>0.4701</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>DMS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>703</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>DMS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2190">
         <PDBx:U11>0.3460</PDBx:U11>
         <PDBx:U12>0.0346</PDBx:U12>
         <PDBx:U13>-0.0724</PDBx:U13>
         <PDBx:U22>0.2774</PDBx:U22>
         <PDBx:U23>-0.0947</PDBx:U23>
         <PDBx:U33>0.4572</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>DMS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>703</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>DMS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2191">
         <PDBx:U11>0.3797</PDBx:U11>
         <PDBx:U12>0.0135</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.2439</PDBx:U22>
         <PDBx:U23>-0.0513</PDBx:U23>
         <PDBx:U33>0.3598</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>DMS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>703</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>DMS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2638</PDBx:U11>
         <PDBx:U12>-0.0058</PDBx:U12>
         <PDBx:U13>-0.0174</PDBx:U13>
         <PDBx:U22>0.1333</PDBx:U22>
         <PDBx:U23>0.0126</PDBx:U23>
         <PDBx:U33>0.2961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1001</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2193">
         <PDBx:U11>0.2263</PDBx:U11>
         <PDBx:U12>-0.0178</PDBx:U12>
         <PDBx:U13>-0.0090</PDBx:U13>
         <PDBx:U22>0.1616</PDBx:U22>
         <PDBx:U23>0.0209</PDBx:U23>
         <PDBx:U33>0.2280</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1002</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2570</PDBx:U11>
         <PDBx:U12>-0.0058</PDBx:U12>
         <PDBx:U13>-0.0075</PDBx:U13>
         <PDBx:U22>0.1741</PDBx:U22>
         <PDBx:U23>-0.0071</PDBx:U23>
         <PDBx:U33>0.1764</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1003</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2195">
         <PDBx:U11>0.2098</PDBx:U11>
         <PDBx:U12>-0.0041</PDBx:U12>
         <PDBx:U13>-0.0243</PDBx:U13>
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         <PDBx:U23>0.0063</PDBx:U23>
         <PDBx:U33>0.1997</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1004</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2196">
         <PDBx:U11>0.4531</PDBx:U11>
         <PDBx:U12>-0.0987</PDBx:U12>
         <PDBx:U13>0.1064</PDBx:U13>
         <PDBx:U22>0.2728</PDBx:U22>
         <PDBx:U23>-0.0379</PDBx:U23>
         <PDBx:U33>0.4912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1005</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2120</PDBx:U11>
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         <PDBx:U13>-0.0465</PDBx:U13>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1006</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2155</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1007</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2199">
         <PDBx:U11>0.2403</PDBx:U11>
         <PDBx:U12>0.0272</PDBx:U12>
         <PDBx:U13>0.0166</PDBx:U13>
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         <PDBx:U23>-0.0010</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1008</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.1983</PDBx:U11>
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         <PDBx:U23>0.0058</PDBx:U23>
         <PDBx:U33>0.2027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1009</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2307</PDBx:U11>
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         <PDBx:U13>-0.0276</PDBx:U13>
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         <PDBx:U23>0.0003</PDBx:U23>
         <PDBx:U33>0.1998</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1010</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2573</PDBx:U11>
         <PDBx:U12>0.0201</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.2708</PDBx:U22>
         <PDBx:U23>0.0122</PDBx:U23>
         <PDBx:U33>0.2364</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1011</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2523</PDBx:U11>
         <PDBx:U12>-0.0040</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.2070</PDBx:U22>
         <PDBx:U23>-0.0139</PDBx:U23>
         <PDBx:U33>0.2405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1012</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.3001</PDBx:U11>
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         <PDBx:U13>-0.0086</PDBx:U13>
         <PDBx:U22>0.2313</PDBx:U22>
         <PDBx:U23>-0.0092</PDBx:U23>
         <PDBx:U33>0.2059</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1013</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2864</PDBx:U11>
         <PDBx:U12>-0.0202</PDBx:U12>
         <PDBx:U13>-0.0337</PDBx:U13>
         <PDBx:U22>0.2502</PDBx:U22>
         <PDBx:U23>0.0210</PDBx:U23>
         <PDBx:U33>0.2237</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1014</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2206">
         <PDBx:U11>0.2452</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>0.0118</PDBx:U13>
         <PDBx:U22>0.2012</PDBx:U22>
         <PDBx:U23>0.0045</PDBx:U23>
         <PDBx:U33>0.2389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1015</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2616</PDBx:U11>
         <PDBx:U12>-0.0132</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.1865</PDBx:U22>
         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.2349</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1016</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2381</PDBx:U11>
         <PDBx:U12>-0.0257</PDBx:U12>
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         <PDBx:U23>-0.0093</PDBx:U23>
         <PDBx:U33>0.2091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1017</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2836</PDBx:U11>
         <PDBx:U12>-0.0159</PDBx:U12>
         <PDBx:U13>-0.0023</PDBx:U13>
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         <PDBx:U23>0.0096</PDBx:U23>
         <PDBx:U33>0.2879</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1018</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2922</PDBx:U11>
         <PDBx:U12>0.0047</PDBx:U12>
         <PDBx:U13>-0.0091</PDBx:U13>
         <PDBx:U22>0.2525</PDBx:U22>
         <PDBx:U23>0.0084</PDBx:U23>
         <PDBx:U33>0.2083</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1019</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.6106</PDBx:U11>
         <PDBx:U12>0.0130</PDBx:U12>
         <PDBx:U13>-0.0447</PDBx:U13>
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         <PDBx:U23>-0.0333</PDBx:U23>
         <PDBx:U33>0.5236</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1020</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>-0.0437</PDBx:U13>
         <PDBx:U22>0.2317</PDBx:U22>
         <PDBx:U23>-0.0192</PDBx:U23>
         <PDBx:U33>0.2395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1021</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2483</PDBx:U11>
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         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.4048</PDBx:U22>
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         <PDBx:U33>0.2555</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1022</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3068</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1023</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2996</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1024</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3004</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1025</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2365</PDBx:U11>
         <PDBx:U12>0.0289</PDBx:U12>
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         <PDBx:U23>0.0315</PDBx:U23>
         <PDBx:U33>0.2589</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1026</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2105</PDBx:U11>
         <PDBx:U12>-0.0021</PDBx:U12>
         <PDBx:U13>0.0142</PDBx:U13>
         <PDBx:U22>0.2575</PDBx:U22>
         <PDBx:U23>0.0184</PDBx:U23>
         <PDBx:U33>0.2069</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1027</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.3290</PDBx:U11>
         <PDBx:U12>-0.0352</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
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         <PDBx:U23>-0.0268</PDBx:U23>
         <PDBx:U33>0.2521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1028</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2736</PDBx:U11>
         <PDBx:U12>-0.0002</PDBx:U12>
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         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.2862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1029</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2221">
         <PDBx:U11>0.2636</PDBx:U11>
         <PDBx:U12>-0.0354</PDBx:U12>
         <PDBx:U13>-0.0480</PDBx:U13>
         <PDBx:U22>0.3194</PDBx:U22>
         <PDBx:U23>0.0460</PDBx:U23>
         <PDBx:U33>0.2975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1030</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2222">
         <PDBx:U11>0.2764</PDBx:U11>
         <PDBx:U12>0.0216</PDBx:U12>
         <PDBx:U13>-0.0229</PDBx:U13>
         <PDBx:U22>0.3046</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.3299</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1031</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2223">
         <PDBx:U11>0.3330</PDBx:U11>
         <PDBx:U12>0.0010</PDBx:U12>
         <PDBx:U13>0.0146</PDBx:U13>
         <PDBx:U22>0.2285</PDBx:U22>
         <PDBx:U23>-0.0095</PDBx:U23>
         <PDBx:U33>0.2324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1032</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2224">
         <PDBx:U11>0.3007</PDBx:U11>
         <PDBx:U12>0.0111</PDBx:U12>
         <PDBx:U13>0.0168</PDBx:U13>
         <PDBx:U22>0.3476</PDBx:U22>
         <PDBx:U23>0.0178</PDBx:U23>
         <PDBx:U33>0.2505</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1033</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2225">
         <PDBx:U11>0.2952</PDBx:U11>
         <PDBx:U12>0.0108</PDBx:U12>
         <PDBx:U13>0.0127</PDBx:U13>
         <PDBx:U22>0.2597</PDBx:U22>
         <PDBx:U23>0.0232</PDBx:U23>
         <PDBx:U33>0.3588</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1034</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2226">
         <PDBx:U11>0.3460</PDBx:U11>
         <PDBx:U12>0.0472</PDBx:U12>
         <PDBx:U13>-0.0681</PDBx:U13>
         <PDBx:U22>0.3426</PDBx:U22>
         <PDBx:U23>0.0169</PDBx:U23>
         <PDBx:U33>0.2437</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1035</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2609</PDBx:U11>
         <PDBx:U12>-0.0324</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.3037</PDBx:U22>
         <PDBx:U23>-0.0424</PDBx:U23>
         <PDBx:U33>0.3153</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1036</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2444</PDBx:U11>
         <PDBx:U12>0.0429</PDBx:U12>
         <PDBx:U13>0.0194</PDBx:U13>
         <PDBx:U22>0.2686</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.1920</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1037</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2229">
         <PDBx:U11>0.2622</PDBx:U11>
         <PDBx:U12>0.0273</PDBx:U12>
         <PDBx:U13>-0.0356</PDBx:U13>
         <PDBx:U22>0.3173</PDBx:U22>
         <PDBx:U23>-0.0449</PDBx:U23>
         <PDBx:U33>0.2521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1038</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2839</PDBx:U11>
         <PDBx:U12>-0.0210</PDBx:U12>
         <PDBx:U13>0.0322</PDBx:U13>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1039</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1040</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2601</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1041</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.3449</PDBx:U11>
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         <PDBx:U13>-0.0458</PDBx:U13>
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         <PDBx:U33>0.3290</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1042</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.3999</PDBx:U11>
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         <PDBx:U23>0.0216</PDBx:U23>
         <PDBx:U33>0.2892</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1043</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2322</PDBx:U11>
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         <PDBx:U13>0.0049</PDBx:U13>
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         <PDBx:U23>-0.0121</PDBx:U23>
         <PDBx:U33>0.1981</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1044</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2973</PDBx:U11>
         <PDBx:U12>-0.0311</PDBx:U12>
         <PDBx:U13>0.0367</PDBx:U13>
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         <PDBx:U23>-0.0413</PDBx:U23>
         <PDBx:U33>0.3027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1045</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3616</PDBx:U11>
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         <PDBx:U13>-0.0236</PDBx:U13>
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         <PDBx:U23>0.0356</PDBx:U23>
         <PDBx:U33>0.3231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1046</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2238">
         <PDBx:U11>0.3803</PDBx:U11>
         <PDBx:U12>0.0285</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.2630</PDBx:U22>
         <PDBx:U23>-0.0271</PDBx:U23>
         <PDBx:U33>0.3683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1047</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2239">
         <PDBx:U11>0.3421</PDBx:U11>
         <PDBx:U12>0.0311</PDBx:U12>
         <PDBx:U13>-0.0732</PDBx:U13>
         <PDBx:U22>0.2617</PDBx:U22>
         <PDBx:U23>-0.0127</PDBx:U23>
         <PDBx:U33>0.2501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1048</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U12>-0.0889</PDBx:U12>
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         <PDBx:U22>0.4458</PDBx:U22>
         <PDBx:U23>0.0560</PDBx:U23>
         <PDBx:U33>0.3703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1049</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3640</PDBx:U11>
         <PDBx:U12>-0.0054</PDBx:U12>
         <PDBx:U13>-0.0082</PDBx:U13>
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         <PDBx:U23>0.0257</PDBx:U23>
         <PDBx:U33>0.2786</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1050</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.4236</PDBx:U11>
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         <PDBx:U13>-0.0427</PDBx:U13>
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         <PDBx:U33>0.4187</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1051</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2711</PDBx:U11>
         <PDBx:U12>-0.0310</PDBx:U12>
         <PDBx:U13>-0.0040</PDBx:U13>
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         <PDBx:U33>0.2892</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1052</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3576</PDBx:U11>
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         <PDBx:U13>0.0705</PDBx:U13>
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         <PDBx:U33>0.3102</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1053</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3654</PDBx:U11>
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         <PDBx:U13>0.0183</PDBx:U13>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1054</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3837</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1055</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1056</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1057</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1058</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1059</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1060</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1061</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1062</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1063</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1064</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1065</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1066</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1067</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1068</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1069</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1070</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1071</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1072</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3277</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1073</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3811</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1074</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4653</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1075</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3590</PDBx:U11>
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         <PDBx:U23>-0.1575</PDBx:U23>
         <PDBx:U33>0.3010</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1076</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2921</PDBx:U11>
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         <PDBx:U33>0.3790</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1077</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4474</PDBx:U11>
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         <PDBx:U33>0.3350</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1078</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3008</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1079</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3828</PDBx:U11>
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         <PDBx:U13>-0.0283</PDBx:U13>
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         <PDBx:U33>0.3392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1080</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2272">
         <PDBx:U11>0.3307</PDBx:U11>
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         <PDBx:U13>0.0335</PDBx:U13>
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         <PDBx:U23>0.0245</PDBx:U23>
         <PDBx:U33>0.3527</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1081</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1082</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3762</PDBx:U11>
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         <PDBx:U23>-0.0277</PDBx:U23>
         <PDBx:U33>0.3595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1083</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2976</PDBx:U11>
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         <PDBx:U23>0.0223</PDBx:U23>
         <PDBx:U33>0.3728</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1084</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3316</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1085</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1086</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1087</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1088</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1089</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1090</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1091</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1092</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1093</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1094</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1095</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1096</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1097</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1098</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1099</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1102</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1103</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1104</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1105</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2297">
         <PDBx:U11>0.3268</PDBx:U11>
         <PDBx:U12>-0.0108</PDBx:U12>
         <PDBx:U13>-0.1253</PDBx:U13>
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         <PDBx:U23>-0.0239</PDBx:U23>
         <PDBx:U33>0.4620</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1106</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2298">
         <PDBx:U11>0.3904</PDBx:U11>
         <PDBx:U12>-0.0484</PDBx:U12>
         <PDBx:U13>-0.0871</PDBx:U13>
         <PDBx:U22>0.4231</PDBx:U22>
         <PDBx:U23>-0.0426</PDBx:U23>
         <PDBx:U33>0.5170</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1107</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2299">
         <PDBx:U11>0.4638</PDBx:U11>
         <PDBx:U12>-0.0454</PDBx:U12>
         <PDBx:U13>-0.1499</PDBx:U13>
         <PDBx:U22>0.2752</PDBx:U22>
         <PDBx:U23>0.1161</PDBx:U23>
         <PDBx:U33>0.5996</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1108</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2300">
         <PDBx:U11>0.3943</PDBx:U11>
         <PDBx:U12>-0.0913</PDBx:U12>
         <PDBx:U13>-0.0697</PDBx:U13>
         <PDBx:U22>0.4803</PDBx:U22>
         <PDBx:U23>-0.0630</PDBx:U23>
         <PDBx:U33>0.3167</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1109</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2301">
         <PDBx:U11>0.3837</PDBx:U11>
         <PDBx:U12>0.0413</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>0.3355</PDBx:U22>
         <PDBx:U23>-0.0321</PDBx:U23>
         <PDBx:U33>0.3869</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1110</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2302">
         <PDBx:U11>0.4789</PDBx:U11>
         <PDBx:U12>-0.0808</PDBx:U12>
         <PDBx:U13>0.1259</PDBx:U13>
         <PDBx:U22>0.3914</PDBx:U22>
         <PDBx:U23>0.1187</PDBx:U23>
         <PDBx:U33>0.7795</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1111</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2303">
         <PDBx:U11>0.4361</PDBx:U11>
         <PDBx:U12>-0.0455</PDBx:U12>
         <PDBx:U13>-0.0595</PDBx:U13>
         <PDBx:U22>0.4805</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.5284</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1112</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2304">
         <PDBx:U11>0.5998</PDBx:U11>
         <PDBx:U12>0.0438</PDBx:U12>
         <PDBx:U13>-0.0815</PDBx:U13>
         <PDBx:U22>0.2439</PDBx:U22>
         <PDBx:U23>-0.0399</PDBx:U23>
         <PDBx:U33>0.6046</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1113</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2305">
         <PDBx:U11>0.4217</PDBx:U11>
         <PDBx:U12>0.0718</PDBx:U12>
         <PDBx:U13>0.1285</PDBx:U13>
         <PDBx:U22>0.4068</PDBx:U22>
         <PDBx:U23>0.0472</PDBx:U23>
         <PDBx:U33>0.4050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1114</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2306">
         <PDBx:U11>0.2951</PDBx:U11>
         <PDBx:U12>0.0139</PDBx:U12>
         <PDBx:U13>0.0732</PDBx:U13>
         <PDBx:U22>0.3672</PDBx:U22>
         <PDBx:U23>0.1324</PDBx:U23>
         <PDBx:U33>0.5865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1115</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2307">
         <PDBx:U11>0.3473</PDBx:U11>
         <PDBx:U12>-0.0536</PDBx:U12>
         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.4378</PDBx:U22>
         <PDBx:U23>0.1126</PDBx:U23>
         <PDBx:U33>0.3583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1116</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2308">
         <PDBx:U11>0.4154</PDBx:U11>
         <PDBx:U12>0.0381</PDBx:U12>
         <PDBx:U13>-0.0227</PDBx:U13>
         <PDBx:U22>0.3340</PDBx:U22>
         <PDBx:U23>-0.0213</PDBx:U23>
         <PDBx:U33>0.5370</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1117</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2309">
         <PDBx:U11>0.3318</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.4018</PDBx:U22>
         <PDBx:U23>0.0582</PDBx:U23>
         <PDBx:U33>0.3317</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1118</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2310">
         <PDBx:U11>0.4730</PDBx:U11>
         <PDBx:U12>0.0828</PDBx:U12>
         <PDBx:U13>-0.0378</PDBx:U13>
         <PDBx:U22>0.4252</PDBx:U22>
         <PDBx:U23>0.0274</PDBx:U23>
         <PDBx:U33>0.3221</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1119</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2311">
         <PDBx:U11>0.4611</PDBx:U11>
         <PDBx:U12>0.0999</PDBx:U12>
         <PDBx:U13>0.0580</PDBx:U13>
         <PDBx:U22>0.4511</PDBx:U22>
         <PDBx:U23>-0.0069</PDBx:U23>
         <PDBx:U33>0.4437</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1120</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2312">
         <PDBx:U11>0.4476</PDBx:U11>
         <PDBx:U12>-0.0117</PDBx:U12>
         <PDBx:U13>0.1053</PDBx:U13>
         <PDBx:U22>0.4431</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.3975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1121</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2313">
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1122</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3961</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1123</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4471</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1124</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.8775</PDBx:U11>
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         <PDBx:U33>0.5705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1125</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.0070</PDBx:U23>
         <PDBx:U33>0.2678</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1126</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4519</PDBx:U11>
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         <PDBx:U13>0.0512</PDBx:U13>
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         <PDBx:U23>0.0611</PDBx:U23>
         <PDBx:U33>0.8974</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1127</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3263</PDBx:U11>
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         <PDBx:U23>-0.0404</PDBx:U23>
         <PDBx:U33>0.3476</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1128</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3692</PDBx:U11>
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         <PDBx:U13>0.0464</PDBx:U13>
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         <PDBx:U23>0.0205</PDBx:U23>
         <PDBx:U33>0.3707</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1129</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2321">
         <PDBx:U11>0.6116</PDBx:U11>
         <PDBx:U12>0.2950</PDBx:U12>
         <PDBx:U13>-0.2332</PDBx:U13>
         <PDBx:U22>0.5356</PDBx:U22>
         <PDBx:U23>-0.1576</PDBx:U23>
         <PDBx:U33>0.5951</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1130</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2961</PDBx:U11>
         <PDBx:U12>0.0180</PDBx:U12>
         <PDBx:U13>-0.0283</PDBx:U13>
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         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.3516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1131</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.6473</PDBx:U11>
         <PDBx:U12>-0.1056</PDBx:U12>
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         <PDBx:U23>-0.0589</PDBx:U23>
         <PDBx:U33>0.6399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1132</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4422</PDBx:U11>
         <PDBx:U12>-0.0784</PDBx:U12>
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         <PDBx:U23>0.0895</PDBx:U23>
         <PDBx:U33>0.4168</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1133</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.4456</PDBx:U11>
         <PDBx:U12>0.1211</PDBx:U12>
         <PDBx:U13>-0.0746</PDBx:U13>
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         <PDBx:U23>-0.0746</PDBx:U23>
         <PDBx:U33>0.5072</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1134</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.4714</PDBx:U11>
         <PDBx:U12>-0.0918</PDBx:U12>
         <PDBx:U13>-0.0872</PDBx:U13>
         <PDBx:U22>0.3492</PDBx:U22>
         <PDBx:U23>-0.0563</PDBx:U23>
         <PDBx:U33>0.4125</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1135</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3480</PDBx:U11>
         <PDBx:U12>-0.0194</PDBx:U12>
         <PDBx:U13>-0.0191</PDBx:U13>
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         <PDBx:U33>0.6203</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1136</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.6780</PDBx:U11>
         <PDBx:U12>-0.1103</PDBx:U12>
         <PDBx:U13>0.1098</PDBx:U13>
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         <PDBx:U33>0.6427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1137</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4430</PDBx:U11>
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         <PDBx:U33>0.3711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1138</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1139</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.9270</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1140</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4014</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1141</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.7599</PDBx:U11>
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         <PDBx:U23>-0.0876</PDBx:U23>
         <PDBx:U33>0.9359</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1142</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4856</PDBx:U11>
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         <PDBx:U23>-0.1224</PDBx:U23>
         <PDBx:U33>0.4016</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1143</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.5948</PDBx:U11>
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         <PDBx:U33>0.6574</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1144</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.8728</PDBx:U11>
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         <PDBx:U23>0.1258</PDBx:U23>
         <PDBx:U33>0.4707</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1145</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2337">
         <PDBx:U11>0.5264</PDBx:U11>
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         <PDBx:U13>0.2236</PDBx:U13>
         <PDBx:U22>0.7022</PDBx:U22>
         <PDBx:U23>-0.2133</PDBx:U23>
         <PDBx:U33>0.5525</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1146</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2338">
         <PDBx:U11>0.4912</PDBx:U11>
         <PDBx:U12>0.0404</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.3515</PDBx:U22>
         <PDBx:U23>0.0073</PDBx:U23>
         <PDBx:U33>0.4789</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1147</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2339">
         <PDBx:U11>0.3309</PDBx:U11>
         <PDBx:U12>0.0626</PDBx:U12>
         <PDBx:U13>0.0316</PDBx:U13>
         <PDBx:U22>0.3059</PDBx:U22>
         <PDBx:U23>0.0262</PDBx:U23>
         <PDBx:U33>0.3496</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1148</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2340">
         <PDBx:U11>0.3303</PDBx:U11>
         <PDBx:U12>-0.0306</PDBx:U12>
         <PDBx:U13>-0.0450</PDBx:U13>
         <PDBx:U22>0.3187</PDBx:U22>
         <PDBx:U23>0.0575</PDBx:U23>
         <PDBx:U33>0.3146</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1149</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.3020</PDBx:U11>
         <PDBx:U12>-0.0177</PDBx:U12>
         <PDBx:U13>-0.0340</PDBx:U13>
         <PDBx:U22>0.4025</PDBx:U22>
         <PDBx:U23>0.0213</PDBx:U23>
         <PDBx:U33>0.4538</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1150</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.4310</PDBx:U11>
         <PDBx:U12>-0.0344</PDBx:U12>
         <PDBx:U13>0.0290</PDBx:U13>
         <PDBx:U22>0.3229</PDBx:U22>
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         <PDBx:U33>0.4073</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1151</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.3715</PDBx:U11>
         <PDBx:U12>-0.0240</PDBx:U12>
         <PDBx:U13>-0.0216</PDBx:U13>
         <PDBx:U22>0.3707</PDBx:U22>
         <PDBx:U23>-0.0173</PDBx:U23>
         <PDBx:U33>0.3924</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1152</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3232</PDBx:U11>
         <PDBx:U12>-0.0106</PDBx:U12>
         <PDBx:U13>0.0805</PDBx:U13>
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         <PDBx:U23>-0.0840</PDBx:U23>
         <PDBx:U33>0.4269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1153</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2895</PDBx:U11>
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         <PDBx:U13>0.0029</PDBx:U13>
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         <PDBx:U33>0.4499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1154</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.5091</PDBx:U11>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1155</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3807</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1156</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4789</PDBx:U11>
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         <PDBx:U23>-0.0229</PDBx:U23>
         <PDBx:U33>0.2890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1157</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.5629</PDBx:U11>
         <PDBx:U12>-0.0582</PDBx:U12>
         <PDBx:U13>0.0710</PDBx:U13>
         <PDBx:U22>0.3432</PDBx:U22>
         <PDBx:U23>0.1135</PDBx:U23>
         <PDBx:U33>0.5257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1158</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.5485</PDBx:U11>
         <PDBx:U12>-0.1520</PDBx:U12>
         <PDBx:U13>0.1916</PDBx:U13>
         <PDBx:U22>0.3800</PDBx:U22>
         <PDBx:U23>-0.0077</PDBx:U23>
         <PDBx:U33>0.3996</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1159</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.3559</PDBx:U11>
         <PDBx:U12>-0.0643</PDBx:U12>
         <PDBx:U13>0.0758</PDBx:U13>
         <PDBx:U22>0.4195</PDBx:U22>
         <PDBx:U23>0.1388</PDBx:U23>
         <PDBx:U33>0.5484</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1160</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.4680</PDBx:U11>
         <PDBx:U12>0.0299</PDBx:U12>
         <PDBx:U13>0.0770</PDBx:U13>
         <PDBx:U22>0.4674</PDBx:U22>
         <PDBx:U23>-0.0061</PDBx:U23>
         <PDBx:U33>0.3495</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1161</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4265</PDBx:U11>
         <PDBx:U12>0.0922</PDBx:U12>
         <PDBx:U13>-0.1616</PDBx:U13>
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         <PDBx:U23>-0.1130</PDBx:U23>
         <PDBx:U33>0.7080</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1162</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2354">
         <PDBx:U11>0.5158</PDBx:U11>
         <PDBx:U12>0.2319</PDBx:U12>
         <PDBx:U13>0.0335</PDBx:U13>
         <PDBx:U22>0.5198</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.5187</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1163</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2355">
         <PDBx:U11>0.3683</PDBx:U11>
         <PDBx:U12>-0.0916</PDBx:U12>
         <PDBx:U13>0.0704</PDBx:U13>
         <PDBx:U22>0.3946</PDBx:U22>
         <PDBx:U23>0.1016</PDBx:U23>
         <PDBx:U33>0.5711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1164</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2356">
         <PDBx:U11>0.4699</PDBx:U11>
         <PDBx:U12>0.0127</PDBx:U12>
         <PDBx:U13>-0.0688</PDBx:U13>
         <PDBx:U22>0.3414</PDBx:U22>
         <PDBx:U23>0.0347</PDBx:U23>
         <PDBx:U33>0.3423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1165</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.4332</PDBx:U11>
         <PDBx:U12>-0.0560</PDBx:U12>
         <PDBx:U13>0.0296</PDBx:U13>
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         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.3641</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1166</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.4786</PDBx:U11>
         <PDBx:U12>0.0561</PDBx:U12>
         <PDBx:U13>0.0123</PDBx:U13>
         <PDBx:U22>0.3372</PDBx:U22>
         <PDBx:U23>-0.0566</PDBx:U23>
         <PDBx:U33>0.4155</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1167</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.4369</PDBx:U11>
         <PDBx:U12>0.0365</PDBx:U12>
         <PDBx:U13>-0.0429</PDBx:U13>
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         <PDBx:U33>0.4663</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1168</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.5373</PDBx:U11>
         <PDBx:U12>-0.0665</PDBx:U12>
         <PDBx:U13>-0.0930</PDBx:U13>
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         <PDBx:U33>0.4425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1169</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3051</PDBx:U11>
         <PDBx:U12>-0.0534</PDBx:U12>
         <PDBx:U13>0.0826</PDBx:U13>
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         <PDBx:U23>-0.1833</PDBx:U23>
         <PDBx:U33>0.4360</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1170</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.3361</PDBx:U11>
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         <PDBx:U13>-0.0888</PDBx:U13>
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         <PDBx:U33>0.5239</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1171</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2363">
         <PDBx:U11>0.5568</PDBx:U11>
         <PDBx:U12>0.1717</PDBx:U12>
         <PDBx:U13>-0.0975</PDBx:U13>
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         <PDBx:U23>0.0821</PDBx:U23>
         <PDBx:U33>0.4277</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1172</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2364">
         <PDBx:U11>0.4160</PDBx:U11>
         <PDBx:U12>0.1009</PDBx:U12>
         <PDBx:U13>-0.0417</PDBx:U13>
         <PDBx:U22>0.6075</PDBx:U22>
         <PDBx:U23>0.0216</PDBx:U23>
         <PDBx:U33>0.2873</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1173</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2365">
         <PDBx:U11>0.4717</PDBx:U11>
         <PDBx:U12>0.0235</PDBx:U12>
         <PDBx:U13>0.0268</PDBx:U13>
         <PDBx:U22>0.3559</PDBx:U22>
         <PDBx:U23>0.0831</PDBx:U23>
         <PDBx:U33>0.4065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1174</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2366">
         <PDBx:U11>0.5899</PDBx:U11>
         <PDBx:U12>0.1390</PDBx:U12>
         <PDBx:U13>0.0910</PDBx:U13>
         <PDBx:U22>0.3385</PDBx:U22>
         <PDBx:U23>-0.0646</PDBx:U23>
         <PDBx:U33>0.4724</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1175</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2367">
         <PDBx:U11>0.2846</PDBx:U11>
         <PDBx:U12>0.0757</PDBx:U12>
         <PDBx:U13>0.1313</PDBx:U13>
         <PDBx:U22>0.7247</PDBx:U22>
         <PDBx:U23>0.2484</PDBx:U23>
         <PDBx:U33>0.9523</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1176</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2368">
         <PDBx:U11>0.7667</PDBx:U11>
         <PDBx:U12>-0.0614</PDBx:U12>
         <PDBx:U13>0.0470</PDBx:U13>
         <PDBx:U22>0.4824</PDBx:U22>
         <PDBx:U23>-0.1042</PDBx:U23>
         <PDBx:U33>0.3466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1177</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2369">
         <PDBx:U11>0.5640</PDBx:U11>
         <PDBx:U12>0.0409</PDBx:U12>
         <PDBx:U13>-0.0197</PDBx:U13>
         <PDBx:U22>0.4777</PDBx:U22>
         <PDBx:U23>-0.1378</PDBx:U23>
         <PDBx:U33>0.4941</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1178</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2370">
         <PDBx:U11>0.5051</PDBx:U11>
         <PDBx:U12>-0.0624</PDBx:U12>
         <PDBx:U13>-0.0168</PDBx:U13>
         <PDBx:U22>0.5014</PDBx:U22>
         <PDBx:U23>0.0721</PDBx:U23>
         <PDBx:U33>0.4723</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1179</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2371">
         <PDBx:U11>0.5970</PDBx:U11>
         <PDBx:U12>-0.0316</PDBx:U12>
         <PDBx:U13>-0.0420</PDBx:U13>
         <PDBx:U22>0.3737</PDBx:U22>
         <PDBx:U23>0.0535</PDBx:U23>
         <PDBx:U33>0.4814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1180</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2372">
         <PDBx:U11>0.4128</PDBx:U11>
         <PDBx:U12>0.0499</PDBx:U12>
         <PDBx:U13>-0.1001</PDBx:U13>
         <PDBx:U22>0.4049</PDBx:U22>
         <PDBx:U23>0.0413</PDBx:U23>
         <PDBx:U33>0.4463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1181</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2373">
         <PDBx:U11>0.3901</PDBx:U11>
         <PDBx:U12>0.0973</PDBx:U12>
         <PDBx:U13>-0.0626</PDBx:U13>
         <PDBx:U22>0.4779</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.4978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1182</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2374">
         <PDBx:U11>0.4831</PDBx:U11>
         <PDBx:U12>-0.0826</PDBx:U12>
         <PDBx:U13>0.0392</PDBx:U13>
         <PDBx:U22>0.7323</PDBx:U22>
         <PDBx:U23>-0.0430</PDBx:U23>
         <PDBx:U33>0.5152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1183</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2375">
         <PDBx:U11>0.3584</PDBx:U11>
         <PDBx:U12>-0.0936</PDBx:U12>
         <PDBx:U13>0.1163</PDBx:U13>
         <PDBx:U22>0.6773</PDBx:U22>
         <PDBx:U23>-0.0331</PDBx:U23>
         <PDBx:U33>0.6923</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1184</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2376">
         <PDBx:U11>0.5154</PDBx:U11>
         <PDBx:U12>0.1185</PDBx:U12>
         <PDBx:U13>-0.0176</PDBx:U13>
         <PDBx:U22>0.5437</PDBx:U22>
         <PDBx:U23>-0.0960</PDBx:U23>
         <PDBx:U33>0.5797</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1185</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2377">
         <PDBx:U11>0.5625</PDBx:U11>
         <PDBx:U12>0.0355</PDBx:U12>
         <PDBx:U13>0.0785</PDBx:U13>
         <PDBx:U22>0.4318</PDBx:U22>
         <PDBx:U23>0.0688</PDBx:U23>
         <PDBx:U33>0.6304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1186</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2378">
         <PDBx:U11>0.7022</PDBx:U11>
         <PDBx:U12>0.1717</PDBx:U12>
         <PDBx:U13>-0.1689</PDBx:U13>
         <PDBx:U22>0.3052</PDBx:U22>
         <PDBx:U23>-0.0281</PDBx:U23>
         <PDBx:U33>0.6601</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1187</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2379">
         <PDBx:U11>0.5065</PDBx:U11>
         <PDBx:U12>0.1416</PDBx:U12>
         <PDBx:U13>0.0140</PDBx:U13>
         <PDBx:U22>0.4423</PDBx:U22>
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         <PDBx:U33>0.5657</PDBx:U33>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1188</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4926</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1189</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4899</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1190</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.5640</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1191</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4875</PDBx:U11>
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         <PDBx:U33>0.5099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1192</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4592</PDBx:U11>
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         <PDBx:U13>-0.0832</PDBx:U13>
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         <PDBx:U23>0.0533</PDBx:U23>
         <PDBx:U33>0.4923</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1193</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4236</PDBx:U11>
         <PDBx:U12>-0.1786</PDBx:U12>
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         <PDBx:U23>-0.0076</PDBx:U23>
         <PDBx:U33>0.7080</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1194</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4214</PDBx:U11>
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         <PDBx:U22>0.4915</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.4222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1195</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2387">
         <PDBx:U11>0.6417</PDBx:U11>
         <PDBx:U12>0.1114</PDBx:U12>
         <PDBx:U13>-0.2687</PDBx:U13>
         <PDBx:U22>0.7309</PDBx:U22>
         <PDBx:U23>-0.0358</PDBx:U23>
         <PDBx:U33>0.5835</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1196</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2388">
         <PDBx:U11>0.5201</PDBx:U11>
         <PDBx:U12>-0.1823</PDBx:U12>
         <PDBx:U13>0.1837</PDBx:U13>
         <PDBx:U22>0.6962</PDBx:U22>
         <PDBx:U23>-0.1017</PDBx:U23>
         <PDBx:U33>0.7953</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1197</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2389">
         <PDBx:U11>0.4731</PDBx:U11>
         <PDBx:U12>-0.0287</PDBx:U12>
         <PDBx:U13>-0.0245</PDBx:U13>
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         <PDBx:U23>0.0531</PDBx:U23>
         <PDBx:U33>0.3519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1198</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.5751</PDBx:U11>
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         <PDBx:U13>0.0630</PDBx:U13>
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         <PDBx:U33>0.5939</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1199</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4138</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1200</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.5639</PDBx:U11>
         <PDBx:U12>-0.1282</PDBx:U12>
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         <PDBx:U33>0.8263</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1201</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.6455</PDBx:U11>
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         <PDBx:U33>0.6096</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1202</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.7430</PDBx:U11>
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         <PDBx:U13>-0.2124</PDBx:U13>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1203</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.6475</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1204</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1205</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1206</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1207</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1208</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1209</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1210</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1211</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1212</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1213</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1214</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1215</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1216</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1217</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1218</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1219</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1220</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1221</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1222</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1223</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1224</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1225</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1226</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1227</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1228</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1229</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1230</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1231</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1232</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1233</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1234</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1235</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1236</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1237</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1238</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.6289</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1239</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.6053</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1240</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4473</PDBx:U11>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1241</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3327</PDBx:U11>
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         <PDBx:U33>0.5642</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1242</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1243</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U33>0.4334</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1244</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.5002</PDBx:U11>
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         <PDBx:U23>-0.0641</PDBx:U23>
         <PDBx:U33>0.5426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1245</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2437">
         <PDBx:U11>0.6116</PDBx:U11>
         <PDBx:U12>0.0468</PDBx:U12>
         <PDBx:U13>0.1706</PDBx:U13>
         <PDBx:U22>0.5139</PDBx:U22>
         <PDBx:U23>-0.1007</PDBx:U23>
         <PDBx:U33>0.6705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1246</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2438">
         <PDBx:U11>0.5724</PDBx:U11>
         <PDBx:U12>-0.0794</PDBx:U12>
         <PDBx:U13>0.1118</PDBx:U13>
         <PDBx:U22>0.3369</PDBx:U22>
         <PDBx:U23>0.0023</PDBx:U23>
         <PDBx:U33>0.7677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1247</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2439">
         <PDBx:U11>0.7113</PDBx:U11>
         <PDBx:U12>-0.1608</PDBx:U12>
         <PDBx:U13>0.0694</PDBx:U13>
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         <PDBx:U33>0.8012</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1248</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3656</PDBx:U11>
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         <PDBx:U33>0.3765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1249</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.7418</PDBx:U11>
         <PDBx:U12>0.6591</PDBx:U12>
         <PDBx:U13>0.0111</PDBx:U13>
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         <PDBx:U23>-0.0881</PDBx:U23>
         <PDBx:U33>1.1491</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1250</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.4733</PDBx:U11>
         <PDBx:U12>0.0749</PDBx:U12>
         <PDBx:U13>-0.1212</PDBx:U13>
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         <PDBx:U33>0.8415</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1251</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4883</PDBx:U11>
         <PDBx:U12>-0.1147</PDBx:U12>
         <PDBx:U13>0.1715</PDBx:U13>
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         <PDBx:U33>0.5174</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1252</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.7805</PDBx:U11>
         <PDBx:U12>-0.1730</PDBx:U12>
         <PDBx:U13>-0.1227</PDBx:U13>
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         <PDBx:U33>0.6480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1253</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.5136</PDBx:U11>
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         <PDBx:U13>0.2024</PDBx:U13>
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         <PDBx:U33>0.9654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1254</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1255</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1256</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1257</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1258</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1259</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1260</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1261</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.7191</PDBx:U11>
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         <PDBx:U13>-0.0103</PDBx:U13>
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         <PDBx:U23>-0.0861</PDBx:U23>
         <PDBx:U33>0.5860</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1262</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.6290</PDBx:U11>
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         <PDBx:U13>0.0033</PDBx:U13>
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         <PDBx:U33>0.4652</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1263</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.5222</PDBx:U11>
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         <PDBx:U13>0.0477</PDBx:U13>
         <PDBx:U22>0.6120</PDBx:U22>
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         <PDBx:U33>0.3992</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1264</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.7690</PDBx:U11>
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         <PDBx:U23>0.0389</PDBx:U23>
         <PDBx:U33>0.3438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1265</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.3763</PDBx:U11>
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         <PDBx:U13>-0.0478</PDBx:U13>
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         <PDBx:U33>0.4837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1266</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.6521</PDBx:U11>
         <PDBx:U12>-0.3493</PDBx:U12>
         <PDBx:U13>0.0678</PDBx:U13>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1267</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.6499</PDBx:U11>
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         <PDBx:U33>0.5325</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1268</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.7414</PDBx:U11>
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         <PDBx:U13>-0.0290</PDBx:U13>
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         <PDBx:U33>0.7583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1269</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.5707</PDBx:U11>
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         <PDBx:U13>-0.0363</PDBx:U13>
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         <PDBx:U33>0.9406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1270</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2462">
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1271</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1272</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1273</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1274</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1275</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1276</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1277</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1278</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1279</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1280</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1281</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1282</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1283</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1284</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1285</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1286</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1287</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2479">
         <PDBx:U11>0.6769</PDBx:U11>
         <PDBx:U12>0.1194</PDBx:U12>
         <PDBx:U13>0.1653</PDBx:U13>
         <PDBx:U22>0.4408</PDBx:U22>
         <PDBx:U23>0.0858</PDBx:U23>
         <PDBx:U33>0.6086</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1288</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2480">
         <PDBx:U11>0.4539</PDBx:U11>
         <PDBx:U12>-0.0240</PDBx:U12>
         <PDBx:U13>-0.0454</PDBx:U13>
         <PDBx:U22>0.6530</PDBx:U22>
         <PDBx:U23>0.0063</PDBx:U23>
         <PDBx:U33>0.6966</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1289</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2481">
         <PDBx:U11>0.7938</PDBx:U11>
         <PDBx:U12>0.2022</PDBx:U12>
         <PDBx:U13>0.0990</PDBx:U13>
         <PDBx:U22>0.5365</PDBx:U22>
         <PDBx:U23>-0.0830</PDBx:U23>
         <PDBx:U33>0.6830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1290</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2482">
         <PDBx:U11>0.8040</PDBx:U11>
         <PDBx:U12>-0.0613</PDBx:U12>
         <PDBx:U13>0.0174</PDBx:U13>
         <PDBx:U22>0.6250</PDBx:U22>
         <PDBx:U23>0.0371</PDBx:U23>
         <PDBx:U33>0.6107</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1291</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2483">
         <PDBx:U11>0.4785</PDBx:U11>
         <PDBx:U12>0.0726</PDBx:U12>
         <PDBx:U13>0.1297</PDBx:U13>
         <PDBx:U22>0.8771</PDBx:U22>
         <PDBx:U23>0.1048</PDBx:U23>
         <PDBx:U33>0.7821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1292</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2484">
         <PDBx:U11>0.6559</PDBx:U11>
         <PDBx:U12>0.0051</PDBx:U12>
         <PDBx:U13>-0.1020</PDBx:U13>
         <PDBx:U22>0.6765</PDBx:U22>
         <PDBx:U23>0.0921</PDBx:U23>
         <PDBx:U33>0.7932</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1293</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2485">
         <PDBx:U11>0.7500</PDBx:U11>
         <PDBx:U12>-0.2037</PDBx:U12>
         <PDBx:U13>-0.0899</PDBx:U13>
         <PDBx:U22>0.7535</PDBx:U22>
         <PDBx:U23>-0.1011</PDBx:U23>
         <PDBx:U33>0.4407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1294</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2486">
         <PDBx:U11>0.8173</PDBx:U11>
         <PDBx:U12>-0.2851</PDBx:U12>
         <PDBx:U13>-0.0564</PDBx:U13>
         <PDBx:U22>0.7611</PDBx:U22>
         <PDBx:U23>0.1271</PDBx:U23>
         <PDBx:U33>0.6445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1295</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2487">
         <PDBx:U11>0.5873</PDBx:U11>
         <PDBx:U12>0.0627</PDBx:U12>
         <PDBx:U13>0.2416</PDBx:U13>
         <PDBx:U22>0.4672</PDBx:U22>
         <PDBx:U23>0.0182</PDBx:U23>
         <PDBx:U33>0.8708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1296</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2488">
         <PDBx:U11>0.5044</PDBx:U11>
         <PDBx:U12>0.1021</PDBx:U12>
         <PDBx:U13>0.0544</PDBx:U13>
         <PDBx:U22>0.9893</PDBx:U22>
         <PDBx:U23>0.0090</PDBx:U23>
         <PDBx:U33>0.4142</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1297</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2489">
         <PDBx:U11>1.0206</PDBx:U11>
         <PDBx:U12>-0.2619</PDBx:U12>
         <PDBx:U13>-0.0814</PDBx:U13>
         <PDBx:U22>0.4497</PDBx:U22>
         <PDBx:U23>-0.2208</PDBx:U23>
         <PDBx:U33>1.1713</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1298</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2490">
         <PDBx:U11>0.6660</PDBx:U11>
         <PDBx:U12>0.0744</PDBx:U12>
         <PDBx:U13>0.0289</PDBx:U13>
         <PDBx:U22>0.4987</PDBx:U22>
         <PDBx:U23>0.0404</PDBx:U23>
         <PDBx:U33>0.7122</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1299</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2491">
         <PDBx:U11>0.5963</PDBx:U11>
         <PDBx:U12>-0.1636</PDBx:U12>
         <PDBx:U13>0.0371</PDBx:U13>
         <PDBx:U22>0.5589</PDBx:U22>
         <PDBx:U23>-0.1154</PDBx:U23>
         <PDBx:U33>0.5848</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1300</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2492">
         <PDBx:U11>0.3602</PDBx:U11>
         <PDBx:U12>-0.0032</PDBx:U12>
         <PDBx:U13>0.0123</PDBx:U13>
         <PDBx:U22>0.2901</PDBx:U22>
         <PDBx:U23>0.0212</PDBx:U23>
         <PDBx:U33>0.3260</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HOH</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>1301</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>E</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HOH</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id xsi:nil="true" />
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
   </PDBx:atom_site_anisotropCategory>
   <PDBx:atom_sitesCategory>
      <PDBx:atom_sites entry_id="4OT5">
         <PDBx:fract_transf_matrix11>0.013934</PDBx:fract_transf_matrix11>
         <PDBx:fract_transf_matrix12>0.000000</PDBx:fract_transf_matrix12>
         <PDBx:fract_transf_matrix13>0.000000</PDBx:fract_transf_matrix13>
         <PDBx:fract_transf_matrix21>-0.000000</PDBx:fract_transf_matrix21>
         <PDBx:fract_transf_matrix22>0.009429</PDBx:fract_transf_matrix22>
         <PDBx:fract_transf_matrix23>0.000000</PDBx:fract_transf_matrix23>
         <PDBx:fract_transf_matrix31>0.000000</PDBx:fract_transf_matrix31>
         <PDBx:fract_transf_matrix32>-0.000000</PDBx:fract_transf_matrix32>
         <PDBx:fract_transf_matrix33>0.026055</PDBx:fract_transf_matrix33>
         <PDBx:fract_transf_vector1>0.00000</PDBx:fract_transf_vector1>
         <PDBx:fract_transf_vector2>0.00000</PDBx:fract_transf_vector2>
         <PDBx:fract_transf_vector3>0.00000</PDBx:fract_transf_vector3>
      </PDBx:atom_sites>
   </PDBx:atom_sitesCategory>
   <PDBx:atom_typeCategory>
      <PDBx:atom_type symbol="C"></PDBx:atom_type>
      <PDBx:atom_type symbol="N"></PDBx:atom_type>
      <PDBx:atom_type symbol="O"></PDBx:atom_type>
      <PDBx:atom_type symbol="S"></PDBx:atom_type>
   </PDBx:atom_typeCategory>
   <PDBx:audit_authorCategory>
      <PDBx:audit_author pdbx_ordinal="1">
         <PDBx:name>Kuglstatter, A.</PDBx:name>
      </PDBx:audit_author>
      <PDBx:audit_author pdbx_ordinal="2">
         <PDBx:name>Wong, A.</PDBx:name>
      </PDBx:audit_author>
   </PDBx:audit_authorCategory>
   <PDBx:audit_conformCategory>
      <PDBx:audit_conform dict_name="mmcif_pdbx.dic" dict_version="5.312">
         <PDBx:dict_location>http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic</PDBx:dict_location>
      </PDBx:audit_conform>
   </PDBx:audit_conformCategory>
   <PDBx:cellCategory>
      <PDBx:cell entry_id="4OT5">
         <PDBx:Z_PDB>4</PDBx:Z_PDB>
         <PDBx:angle_alpha>90.00</PDBx:angle_alpha>
         <PDBx:angle_beta>90.00</PDBx:angle_beta>
         <PDBx:angle_gamma>90.00</PDBx:angle_gamma>
         <PDBx:length_a>71.768</PDBx:length_a>
         <PDBx:length_b>106.056</PDBx:length_b>
         <PDBx:length_c>38.380</PDBx:length_c>
      </PDBx:cell>
   </PDBx:cellCategory>
   <PDBx:chem_compCategory>
      <PDBx:chem_comp id="481">
         <PDBx:formula>C35 H37 N7 O2</PDBx:formula>
         <PDBx:formula_weight>587.714</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>4-tert-butyl-N-{3-[8-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amino)imidazo[1,2-a]pyrazin-6-yl]phenyl}benzamide</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ALA">
         <PDBx:formula>C3 H7 N O2</PDBx:formula>
         <PDBx:formula_weight>89.093</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ALANINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ARG">
         <PDBx:formula>C6 H15 N4 O2 1</PDBx:formula>
         <PDBx:formula_weight>175.209</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ARGININE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ASN">
         <PDBx:formula>C4 H8 N2 O3</PDBx:formula>
         <PDBx:formula_weight>132.118</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ASPARAGINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ASP">
         <PDBx:formula>C4 H7 N O4</PDBx:formula>
         <PDBx:formula_weight>133.103</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ASPARTIC ACID</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="CYS">
         <PDBx:formula>C3 H7 N O2 S</PDBx:formula>
         <PDBx:formula_weight>121.158</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>CYSTEINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="DMS">
         <PDBx:formula>C2 H6 O S</PDBx:formula>
         <PDBx:formula_weight>78.133</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>DIMETHYL SULFOXIDE</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLN">
         <PDBx:formula>C5 H10 N2 O3</PDBx:formula>
         <PDBx:formula_weight>146.144</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLUTAMINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLU">
         <PDBx:formula>C5 H9 N O4</PDBx:formula>
         <PDBx:formula_weight>147.129</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLUTAMIC ACID</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLY">
         <PDBx:formula>C2 H5 N O2</PDBx:formula>
         <PDBx:formula_weight>75.067</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLYCINE</PDBx:name>
         <PDBx:type>peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="HIS">
         <PDBx:formula>C6 H10 N3 O2 1</PDBx:formula>
         <PDBx:formula_weight>156.162</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>HISTIDINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="HOH">
         <PDBx:formula>H2 O</PDBx:formula>
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>WATER</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ILE">
         <PDBx:formula>C6 H13 N O2</PDBx:formula>
         <PDBx:formula_weight>131.173</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ISOLEUCINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="LEU">
         <PDBx:formula>C6 H13 N O2</PDBx:formula>
         <PDBx:formula_weight>131.173</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>LEUCINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="LYS">
         <PDBx:formula>C6 H15 N2 O2 1</PDBx:formula>
         <PDBx:formula_weight>147.195</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>LYSINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="MET">
         <PDBx:formula>C5 H11 N O2 S</PDBx:formula>
         <PDBx:formula_weight>149.211</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>METHIONINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="PHE">
         <PDBx:formula>C9 H11 N O2</PDBx:formula>
         <PDBx:formula_weight>165.189</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>PHENYLALANINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="PRO">
         <PDBx:formula>C5 H9 N O2</PDBx:formula>
         <PDBx:formula_weight>115.130</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>PROLINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="SER">
         <PDBx:formula>C3 H7 N O3</PDBx:formula>
         <PDBx:formula_weight>105.093</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>SERINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="THR">
         <PDBx:formula>C4 H9 N O3</PDBx:formula>
         <PDBx:formula_weight>119.119</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>THREONINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="TRP">
         <PDBx:formula>C11 H12 N2 O2</PDBx:formula>
         <PDBx:formula_weight>204.225</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>TRYPTOPHAN</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="TYR">
         <PDBx:formula>C9 H11 N O3</PDBx:formula>
         <PDBx:formula_weight>181.189</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>TYROSINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="VAL">
         <PDBx:formula>C5 H11 N O2</PDBx:formula>
         <PDBx:formula_weight>117.146</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>VALINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
   </PDBx:chem_compCategory>
   <PDBx:citationCategory>
      <PDBx:citation id="primary">
         <PDBx:country>US</PDBx:country>
         <PDBx:journal_abbrev>J.Med.Chem.</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>JMCMAR</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0151</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0022-2623</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>58</PDBx:journal_volume>
         <PDBx:page_first>512</PDBx:page_first>
         <PDBx:page_last>516</PDBx:page_last>
         <PDBx:pdbx_database_id_DOI>10.1021/jm500305p</PDBx:pdbx_database_id_DOI>
         <PDBx:pdbx_database_id_PubMed>24712864</PDBx:pdbx_database_id_PubMed>
         <PDBx:title>Structure-Based Drug Design of RN486, a Potent and Selective Bruton&apos;s Tyrosine Kinase (BTK) Inhibitor, for the Treatment of Rheumatoid Arthritis.</PDBx:title>
         <PDBx:year>2015</PDBx:year>
      </PDBx:citation>
   </PDBx:citationCategory>
   <PDBx:citation_authorCategory>
      <PDBx:citation_author citation_id="primary" name="Lou, Y." ordinal="1">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Han, X." ordinal="2">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Kuglstatter, A." ordinal="3">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Kondru, R.K." ordinal="4">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Sweeney, Z.K." ordinal="5">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Soth, M." ordinal="6">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="McIntosh, J." ordinal="7">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Litman, R." ordinal="8">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Suh, J." ordinal="9">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Kocer, B." ordinal="10">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Davis, D." ordinal="11">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Park, J." ordinal="12">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Frauchiger, S." ordinal="13">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Dewdney, N." ordinal="14">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Zecic, H." ordinal="15">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Taygerly, J.P." ordinal="16">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Sarma, K." ordinal="17">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Hong, J." ordinal="18">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Hill, R.J." ordinal="19">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Gabriel, T." ordinal="20">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Goldstein, D.M." ordinal="21">
      </PDBx:citation_author>
      <PDBx:citation_author citation_id="primary" name="Owens, T.D." ordinal="22">
      </PDBx:citation_author>
   </PDBx:citation_authorCategory>
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      <PDBx:database_2 database_code="4OT5" database_id="PDB"></PDBx:database_2>
      <PDBx:database_2 database_code="RCSB084918" database_id="RCSB"></PDBx:database_2>
      <PDBx:database_2 database_code="D_1000084918" database_id="WWPDB"></PDBx:database_2>
   </PDBx:database_2Category>
   <PDBx:database_PDB_matrixCategory>
      <PDBx:database_PDB_matrix entry_id="4OT5">
         <PDBx:origx11>1.000000</PDBx:origx11>
         <PDBx:origx12>0.000000</PDBx:origx12>
         <PDBx:origx13>0.000000</PDBx:origx13>
         <PDBx:origx21>0.000000</PDBx:origx21>
         <PDBx:origx22>1.000000</PDBx:origx22>
         <PDBx:origx23>0.000000</PDBx:origx23>
         <PDBx:origx31>0.000000</PDBx:origx31>
         <PDBx:origx32>0.000000</PDBx:origx32>
         <PDBx:origx33>1.000000</PDBx:origx33>
         <PDBx:origx_vector1>0.00000</PDBx:origx_vector1>
         <PDBx:origx_vector2>0.00000</PDBx:origx_vector2>
         <PDBx:origx_vector3>0.00000</PDBx:origx_vector3>
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      <PDBx:diffrn id="1">
         <PDBx:ambient_temp>100</PDBx:ambient_temp>
         <PDBx:crystal_id>1</PDBx:crystal_id>
      </PDBx:diffrn>
   </PDBx:diffrnCategory>
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      <PDBx:diffrn_detector diffrn_id="1">
         <PDBx:detector>CCD</PDBx:detector>
         <PDBx:type>ADSC QUANTUM 315r</PDBx:type>
      </PDBx:diffrn_detector>
   </PDBx:diffrn_detectorCategory>
   <PDBx:diffrn_radiationCategory>
      <PDBx:diffrn_radiation diffrn_id="1">
         <PDBx:monochromator>Liquid Nitrogen cooled Dual Crystal Si(111)</PDBx:monochromator>
         <PDBx:pdbx_diffrn_protocol>SINGLE WAVELENGTH</PDBx:pdbx_diffrn_protocol>
         <PDBx:pdbx_monochromatic_or_laue_m_l>M</PDBx:pdbx_monochromatic_or_laue_m_l>
         <PDBx:pdbx_scattering_type>x-ray</PDBx:pdbx_scattering_type>
         <PDBx:wavelength_id>1</PDBx:wavelength_id>
      </PDBx:diffrn_radiation>
   </PDBx:diffrn_radiationCategory>
   <PDBx:diffrn_radiation_wavelengthCategory>
      <PDBx:diffrn_radiation_wavelength id="1">
         <PDBx:wavelength>1.0</PDBx:wavelength>
         <PDBx:wt>1.0</PDBx:wt>
      </PDBx:diffrn_radiation_wavelength>
   </PDBx:diffrn_radiation_wavelengthCategory>
   <PDBx:diffrn_sourceCategory>
      <PDBx:diffrn_source diffrn_id="1">
         <PDBx:pdbx_synchrotron_beamline>5.0.2</PDBx:pdbx_synchrotron_beamline>
         <PDBx:pdbx_synchrotron_site>ALS</PDBx:pdbx_synchrotron_site>
         <PDBx:pdbx_wavelength_list>1.0</PDBx:pdbx_wavelength_list>
         <PDBx:source>SYNCHROTRON</PDBx:source>
         <PDBx:type>ALS BEAMLINE 5.0.2</PDBx:type>
      </PDBx:diffrn_source>
   </PDBx:diffrn_sourceCategory>
   <PDBx:entityCategory>
      <PDBx:entity id="1">
         <PDBx:formula_weight>32521.135</PDBx:formula_weight>
         <PDBx:pdbx_description>Tyrosine-protein kinase BTK</PDBx:pdbx_description>
         <PDBx:pdbx_ec>2.7.10.2</PDBx:pdbx_ec>
         <PDBx:pdbx_fragment>UNP residues 378-659</PDBx:pdbx_fragment>
         <PDBx:pdbx_mutation>M489A, R492A, E624A, K625A</PDBx:pdbx_mutation>
         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>man</PDBx:src_method>
         <PDBx:type>polymer</PDBx:type>
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      <PDBx:entity id="2">
         <PDBx:formula_weight>587.714</PDBx:formula_weight>
         <PDBx:pdbx_description>4-tert-butyl-N-{3-[8-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amino)imidazo[1,2-a]pyrazin-6-yl]phenyl}benzamide</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>1</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="3">
         <PDBx:formula_weight>78.133</PDBx:formula_weight>
         <PDBx:pdbx_description>DIMETHYL SULFOXIDE</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>2</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="4">
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:pdbx_description>water</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>301</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>nat</PDBx:src_method>
         <PDBx:type>water</PDBx:type>
      </PDBx:entity>
   </PDBx:entityCategory>
   <PDBx:entity_name_comCategory>
      <PDBx:entity_name_com entity_id="1">
         <PDBx:name>Agammaglobulinemia tyrosine kinase, ATK, B-cell progenitor kinase, BPK, Bruton tyrosine kinase</PDBx:name>
      </PDBx:entity_name_com>
   </PDBx:entity_name_comCategory>
   <PDBx:entity_polyCategory>
      <PDBx:entity_poly entity_id="1">
         <PDBx:nstd_linkage>no</PDBx:nstd_linkage>
         <PDBx:nstd_monomer>no</PDBx:nstd_monomer>
         <PDBx:pdbx_seq_one_letter_code>GSQQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEK
LVQLYGVCTKQRPIFIITEYMANGCLLNYLREARHAFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVK
VSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRL
YRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEES</PDBx:pdbx_seq_one_letter_code>
         <PDBx:pdbx_seq_one_letter_code_can>GSQQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEK
LVQLYGVCTKQRPIFIITEYMANGCLLNYLREARHAFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVK
VSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRL
YRPHLASAAVYTIMYSCWHEKADERPTFKILLSNILDVMDEES</PDBx:pdbx_seq_one_letter_code_can>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:type>polypeptide(L)</PDBx:type>
      </PDBx:entity_poly>
   </PDBx:entity_polyCategory>
   <PDBx:entity_poly_seqCategory>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="1">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="2">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="3">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="4">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="5">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="6">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="7">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="8">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="9">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="10">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="11">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="12">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="13">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="14">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="15">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="16">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="17">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="18">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="19">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="20">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="21">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="22">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="23">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="24">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="25">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="26">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="27">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="28">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="29">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="30">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="31">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="32">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="33">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="34">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="35">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="36">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="37">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="38">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="39">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="40">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="41">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="42">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="43">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="44">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="45">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="46">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="47">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="48">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="49">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="50">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="51">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="52">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="53">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="54">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="55">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="56">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="57">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="58">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="59">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="60">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="61">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="62">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="63">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="64">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="65">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="66">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="67">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="68">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="69">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="70">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="71">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="72">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="73">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="74">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="75">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="76">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="77">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="78">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="79">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="80">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="81">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="82">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="83">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="84">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="85">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="86">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="87">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="88">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="89">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="90">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="91">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="92">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="93">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="94">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="95">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="96">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="97">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="98">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="99">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="100">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="101">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="102">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="103">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="104">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="105">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="106">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="107">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="108">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="109">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="110">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="111">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="112">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="113">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="114">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="115">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="116">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="117">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="118">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="119">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="120">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="121">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="122">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="123">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="124">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="125">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="126">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="127">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="128">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="129">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="130">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="131">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="132">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="133">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="134">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="135">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="136">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="137">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="138">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="139">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="140">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="141">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="142">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="143">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="144">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="145">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="146">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="147">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="148">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="149">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="150">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="151">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="152">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="153">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="154">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="155">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="156">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="157">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="158">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="159">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="160">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="161">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="162">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="163">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="164">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="165">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="166">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="167">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="168">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="169">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="170">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="171">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="172">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="173">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="174">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="175">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="176">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="177">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="178">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="179">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="180">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="181">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="182">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="183">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="184">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="185">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="186">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="187">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="188">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="189">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="190">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="191">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="192">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="193">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="194">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="195">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="196">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="197">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="198">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="199">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="200">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="201">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="202">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="203">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="204">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="205">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="206">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="207">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="208">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="209">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="210">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="211">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="212">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="213">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="214">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="215">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="216">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="217">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="218">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="219">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="220">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="221">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="222">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="223">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="224">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="225">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="226">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="227">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="228">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="229">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="230">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="231">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="232">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="233">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="234">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="235">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="236">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="237">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="238">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="239">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="240">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="241">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="242">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="243">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="244">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="245">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="246">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="247">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="248">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="249">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="250">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="251">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="252">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="253">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="254">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="255">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="256">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="257">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="258">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="259">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="260">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="261">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="262">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="263">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="264">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="265">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="266">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="267">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="268">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="269">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="270">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="271">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="272">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="273">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="274">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="275">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="276">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="277">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="278">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="279">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="280">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="281">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="282">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="283">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
   </PDBx:entity_poly_seqCategory>
   <PDBx:entity_src_genCategory>
      <PDBx:entity_src_gen entity_id="1" pdbx_src_id="1">
         <PDBx:gene_src_common_name>human</PDBx:gene_src_common_name>
         <PDBx:host_org_common_name>fall armyworm</PDBx:host_org_common_name>
         <PDBx:pdbx_alt_source_flag>sample</PDBx:pdbx_alt_source_flag>
         <PDBx:pdbx_gene_src_gene>BTK, AGMX1, ATK, BPK</PDBx:pdbx_gene_src_gene>
         <PDBx:pdbx_gene_src_ncbi_taxonomy_id>9606</PDBx:pdbx_gene_src_ncbi_taxonomy_id>
         <PDBx:pdbx_gene_src_scientific_name>Homo sapiens</PDBx:pdbx_gene_src_scientific_name>
         <PDBx:pdbx_host_org_ncbi_taxonomy_id>7108</PDBx:pdbx_host_org_ncbi_taxonomy_id>
         <PDBx:pdbx_host_org_scientific_name>Spodoptera frugiperda</PDBx:pdbx_host_org_scientific_name>
         <PDBx:pdbx_host_org_vector_type>baculovirus</PDBx:pdbx_host_org_vector_type>
      </PDBx:entity_src_gen>
   </PDBx:entity_src_genCategory>
   <PDBx:entryCategory>
      <PDBx:entry id="4OT5"></PDBx:entry>
   </PDBx:entryCategory>
   <PDBx:exptlCategory>
      <PDBx:exptl entry_id="4OT5" method="X-RAY DIFFRACTION">
         <PDBx:crystals_number>1</PDBx:crystals_number>
      </PDBx:exptl>
   </PDBx:exptlCategory>
   <PDBx:exptl_crystalCategory>
      <PDBx:exptl_crystal id="1">
         <PDBx:density_Matthews>2.25</PDBx:density_Matthews>
         <PDBx:density_percent_sol>45.23</PDBx:density_percent_sol>
      </PDBx:exptl_crystal>
   </PDBx:exptl_crystalCategory>
   <PDBx:exptl_crystal_growCategory>
      <PDBx:exptl_crystal_grow crystal_id="1">
         <PDBx:method>VAPOR DIFFUSION, HANGING DROP</PDBx:method>
         <PDBx:pH>8.0</PDBx:pH>
         <PDBx:pdbx_details>33&#37; PEG3350, 0.1 M HEPES, pH 8.0, VAPOR DIFFUSION, HANGING DROP, temperature 293K</PDBx:pdbx_details>
         <PDBx:temp>293</PDBx:temp>
      </PDBx:exptl_crystal_grow>
   </PDBx:exptl_crystal_growCategory>
   <PDBx:pdbx_audit_revision_categoryCategory>
      <PDBx:pdbx_audit_revision_category data_content_type="Structure model" ordinal="1" revision_ordinal="3">
         <PDBx:category>software</PDBx:category>
      </PDBx:pdbx_audit_revision_category>
   </PDBx:pdbx_audit_revision_categoryCategory>
   <PDBx:pdbx_audit_revision_detailsCategory>
      <PDBx:pdbx_audit_revision_details data_content_type="Structure model" ordinal="1" revision_ordinal="1">
         <PDBx:provider>repository</PDBx:provider>
         <PDBx:type>Initial release</PDBx:type>
      </PDBx:pdbx_audit_revision_details>
   </PDBx:pdbx_audit_revision_detailsCategory>
   <PDBx:pdbx_audit_revision_groupCategory>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="1" revision_ordinal="2">
         <PDBx:group>Database references</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="2" revision_ordinal="3">
         <PDBx:group>Data collection</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="3" revision_ordinal="3">
         <PDBx:group>Refinement description</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
   </PDBx:pdbx_audit_revision_groupCategory>
   <PDBx:pdbx_audit_revision_historyCategory>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="1">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>0</PDBx:minor_revision>
         <PDBx:revision_date>2014-05-14</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="2">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>1</PDBx:minor_revision>
         <PDBx:revision_date>2015-01-21</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="3">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>2</PDBx:minor_revision>
         <PDBx:revision_date>2019-07-17</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
   </PDBx:pdbx_audit_revision_historyCategory>
   <PDBx:pdbx_audit_revision_itemCategory>
      <PDBx:pdbx_audit_revision_item data_content_type="Structure model" ordinal="1" revision_ordinal="3">
         <PDBx:item>_software.classification</PDBx:item>
      </PDBx:pdbx_audit_revision_item>
      <PDBx:pdbx_audit_revision_item data_content_type="Structure model" ordinal="2" revision_ordinal="3">
         <PDBx:item>_software.name</PDBx:item>
      </PDBx:pdbx_audit_revision_item>
      <PDBx:pdbx_audit_revision_item data_content_type="Structure model" ordinal="3" revision_ordinal="3">
         <PDBx:item>_software.version</PDBx:item>
      </PDBx:pdbx_audit_revision_item>
   </PDBx:pdbx_audit_revision_itemCategory>
   <PDBx:pdbx_database_relatedCategory>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="4OT6" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="4OTQ" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="4OTR" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
   </PDBx:pdbx_database_relatedCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="4OT5">
         <PDBx:deposit_site>RCSB</PDBx:deposit_site>
         <PDBx:pdb_format_compatible>Y</PDBx:pdb_format_compatible>
         <PDBx:process_site>RCSB</PDBx:process_site>
         <PDBx:recvd_initial_deposition_date>2014-02-13</PDBx:recvd_initial_deposition_date>
         <PDBx:status_code>REL</PDBx:status_code>
         <PDBx:status_code_sf>REL</PDBx:status_code_sf>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_entity_nonpolyCategory>
      <PDBx:pdbx_entity_nonpoly entity_id="2">
         <PDBx:comp_id>481</PDBx:comp_id>
         <PDBx:name>4-tert-butyl-N-{3-[8-({4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}amino)imidazo[1,2-a]pyrazin-6-yl]phenyl}benzamide</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="3">
         <PDBx:comp_id>DMS</PDBx:comp_id>
         <PDBx:name>DIMETHYL SULFOXIDE</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="4">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="1">
         <PDBx:auth_mon_id>481</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>481</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>481</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>701</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="1">
         <PDBx:auth_mon_id>DMS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>DMS</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DMS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>702</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="1">
         <PDBx:auth_mon_id>DMS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>DMS</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>DMS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>703</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1001</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1001</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1002</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1002</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1003</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1003</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="4">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1004</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1004</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="5">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1005</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1005</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="6">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1007</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1006</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="7">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1008</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1007</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="8">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1009</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1008</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="9">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1010</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1009</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="10">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1011</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1010</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="11">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1012</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1011</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="12">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1013</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1012</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="13">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1014</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1013</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="14">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1015</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1014</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="15">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1016</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1015</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="16">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1017</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1016</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="17">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1018</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1017</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="18">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1019</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1018</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="19">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1020</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1019</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="20">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1021</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1020</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="21">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1022</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1021</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="22">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1023</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1022</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="23">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1024</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1023</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="24">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1025</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1024</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="25">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1026</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1025</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="26">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1027</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1026</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="27">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1028</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1027</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="28">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1029</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1028</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="29">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1030</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1029</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="30">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1031</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1030</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="31">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1032</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1031</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="32">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1033</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1032</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="33">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1034</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1033</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="34">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1036</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1034</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="35">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1037</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1035</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="36">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1038</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1036</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="37">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1039</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1037</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="38">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1040</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1038</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="39">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1041</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1039</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="40">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1042</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1040</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="41">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1043</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1041</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="42">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1044</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1042</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="43">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1045</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1043</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="44">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1046</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1044</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="45">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1047</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1045</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="46">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1048</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1046</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="47">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1050</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1047</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="48">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1051</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1048</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="49">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1052</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1049</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="50">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1053</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1050</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="51">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1054</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1051</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="52">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1055</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1052</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="53">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1056</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1053</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="54">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1057</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1054</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="55">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1058</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1055</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="56">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1059</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1056</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="57">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1060</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1057</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="58">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1061</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1058</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="59">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1062</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1059</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="60">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1063</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1060</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="61">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1064</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1061</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="62">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1065</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1062</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="63">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1066</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1063</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="64">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1067</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1064</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="65">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1068</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1065</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="66">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1069</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1066</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="67">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1070</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1067</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="68">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1071</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1068</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="69">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1072</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1069</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="70">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1073</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1070</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="71">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1074</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1071</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="72">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1075</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1072</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="73">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1076</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1073</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="74">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1077</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1074</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="75">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1079</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1075</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="76">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1080</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1076</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="77">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1081</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1077</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="78">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1082</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1078</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="79">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1083</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1079</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="80">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1084</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1080</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="81">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1085</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1081</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="82">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1086</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1082</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="83">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1087</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1083</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="84">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1088</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1084</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="85">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1089</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1085</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="86">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1090</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1086</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="87">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1091</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1087</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="88">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1092</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1088</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="89">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1093</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1089</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="90">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1094</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1090</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="91">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1095</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1091</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="92">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1096</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1092</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="93">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1097</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1093</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="94">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1098</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1094</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="95">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1099</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1095</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="96">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1100</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1096</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="97">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1101</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1097</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="98">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1102</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1098</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="99">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1103</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1099</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="100">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1104</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1100</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="101">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1105</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1101</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="102">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1106</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1102</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="103">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1107</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1103</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="104">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1108</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1104</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="105">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1109</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1105</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="106">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1110</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1106</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="107">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1111</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1107</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="108">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1113</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1108</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="109">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1114</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1109</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="110">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1115</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1110</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="111">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1116</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1111</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="112">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1117</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1112</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="113">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1118</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1113</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="114">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1119</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1114</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="115">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1120</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1115</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="116">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1121</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1116</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="117">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1123</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1117</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="118">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1124</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1118</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="119">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1125</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1119</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="120">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1127</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1120</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="121">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1128</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1121</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="122">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1129</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1122</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="123">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1131</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1123</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="124">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1132</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1124</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="125">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1133</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1125</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="126">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1134</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1126</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="127">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1135</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1127</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="128">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1136</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1128</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="129">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1140</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1129</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="130">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1142</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1130</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="131">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1144</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1131</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="132">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1148</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1132</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="133">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1149</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1133</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="134">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1150</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1134</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="135">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1158</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1135</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="136">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1160</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1136</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="137">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1164</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1137</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="138">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1165</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1138</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="139">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1172</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1139</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="140">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1173</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1140</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="141">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1176</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1141</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="142">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1177</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1142</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="143">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1179</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1143</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="144">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1183</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1144</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="145">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1192</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1145</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="146">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1193</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1146</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="147">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1197</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1147</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="148">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2001</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1148</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="149">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2002</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1149</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="150">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2003</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1150</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="151">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2004</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1151</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="152">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2006</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1152</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="153">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2007</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1153</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="154">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2008</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1154</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="155">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2009</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1155</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="156">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2010</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1156</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="157">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2011</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1157</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="158">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2012</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1158</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="159">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2013</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1159</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="160">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2014</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1160</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="161">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2015</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1161</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="162">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2016</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1162</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="163">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2018</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1163</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="164">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2019</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1164</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="165">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2020</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1165</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="166">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2021</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1166</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="167">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2022</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1167</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="168">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2023</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1168</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="169">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2024</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1169</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="170">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2025</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1170</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="171">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2026</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1171</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="172">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2027</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1172</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="173">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2028</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1173</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="174">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2029</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1174</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="175">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2030</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1175</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="176">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2031</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1176</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="177">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2032</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1177</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="178">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2033</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1178</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="179">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2034</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1179</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="180">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2035</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1180</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="181">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2036</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1181</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="182">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2037</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1182</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="183">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2038</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1183</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="184">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2039</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1184</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="185">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2040</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1185</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="186">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2041</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1186</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="187">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2042</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1187</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="188">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2043</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1188</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="189">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2044</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1189</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="190">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2045</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1190</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="191">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2046</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1191</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="192">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2047</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1192</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="193">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2048</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1193</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="194">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2049</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1194</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="195">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2050</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1195</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="196">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2051</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1196</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="197">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2052</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1197</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="198">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2053</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1198</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="199">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2054</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1199</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="200">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2055</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1200</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="201">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2056</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1201</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="202">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2058</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1202</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="203">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2059</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1203</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="204">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2060</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1204</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="205">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2061</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1205</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="206">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2062</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1206</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="207">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2063</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1207</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="208">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2064</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1208</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="209">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2066</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1209</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="210">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2067</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1210</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="211">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2068</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1211</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="212">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2069</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1212</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="213">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2071</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1213</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="214">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2073</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1214</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="215">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2074</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1215</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="216">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2075</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1216</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="217">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2076</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1217</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="218">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2077</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1218</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="219">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2080</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1219</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="220">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2081</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1220</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="221">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2083</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1221</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="222">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2084</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1222</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="223">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2085</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1223</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="224">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2086</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1224</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="225">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2087</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1225</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="226">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2088</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1226</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="227">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2089</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1227</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="228">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2090</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1228</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="229">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2091</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1229</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="230">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2092</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1230</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="231">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2096</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1231</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="232">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2097</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1232</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="233">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2099</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1233</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="234">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2103</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1234</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="235">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2104</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1235</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="236">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2105</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1236</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="237">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2106</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1237</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="238">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2107</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1238</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="239">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2108</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1239</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="240">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2109</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1240</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="241">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2111</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1241</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="242">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2112</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1242</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="243">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2114</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1243</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="244">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2115</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1244</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="245">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2117</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1245</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="246">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2122</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1246</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="247">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2124</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1247</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="248">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2128</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1248</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="249">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2129</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1249</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="250">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2133</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1250</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="251">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2140</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1251</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="252">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2149</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1252</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="253">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2150</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1253</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="254">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2163</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1254</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="255">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3002</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1255</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="256">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3003</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1256</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="257">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3005</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1257</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="258">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3006</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1258</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="259">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3007</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1259</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="260">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3009</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1260</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="261">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3012</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1261</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="262">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3013</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1262</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="263">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3014</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1263</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="264">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3016</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1264</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="265">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3017</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1265</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="266">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3018</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1266</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="267">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3019</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1267</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="268">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3020</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1268</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="269">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3021</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1269</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="270">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3022</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1270</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="271">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3023</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1271</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="272">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3024</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1272</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="273">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3025</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1273</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="274">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3026</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1274</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="275">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3027</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1275</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="276">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3029</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1276</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="277">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3030</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1277</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="278">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3032</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1278</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="279">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3034</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1279</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="280">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3035</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1280</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="281">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3040</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1281</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="282">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3041</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1282</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="283">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3042</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1283</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="284">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3043</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1284</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="285">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3045</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1285</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="286">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3049</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1286</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="287">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3052</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1287</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="288">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3053</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1288</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="289">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3054</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1289</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="290">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3055</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1290</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="291">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3056</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1291</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="292">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3065</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1292</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="293">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3073</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1293</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="294">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3074</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1294</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="295">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3079</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1295</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="296">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3081</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1296</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="297">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3085</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1297</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="298">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3089</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1298</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="299">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3090</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1299</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="300">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3091</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1300</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="301">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3092</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1301</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="1">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>377</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="2">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>378</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="3">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>379</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="4">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>380</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="5">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>381</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="6">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>382</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="7">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>383</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="8">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>384</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="9">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>385</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="10">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>386</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="11">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>387</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="12">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>388</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="13">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>389</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="14">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>14</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>390</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="15">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>15</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>391</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="16">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>16</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>392</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="17">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>17</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>393</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="18">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>18</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>394</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="19">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>19</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>395</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="20">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>396</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>20</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>396</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="21">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>397</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>21</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>397</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="22">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>398</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>22</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>398</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="23">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>399</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>23</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>399</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="24">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>400</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>24</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>400</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="25">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>401</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>25</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>401</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="26">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>402</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>26</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>402</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="27">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>403</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>27</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>403</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="28">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>404</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>28</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>404</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="29">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>405</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>29</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>405</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="30">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>406</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>30</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>406</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="31">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>407</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>31</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>407</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="32">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>408</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>32</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>408</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="33">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>409</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>33</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>409</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="34">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>410</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>34</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>410</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="35">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>411</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>35</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>411</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="36">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>412</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>36</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>412</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="37">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>413</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>37</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>413</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="38">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>414</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>38</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>414</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="39">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>415</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>39</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>415</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="40">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>416</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>40</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>416</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="41">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>417</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>41</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>417</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="42">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>418</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>42</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>418</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="43">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>419</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>43</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>419</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="44">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>420</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>44</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>420</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="45">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>421</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>45</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>421</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="46">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>422</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>46</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>422</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="47">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>423</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>47</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>423</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="48">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>424</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>48</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>424</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="49">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>425</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>49</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>425</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="50">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>426</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>50</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>426</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="51">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>427</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>51</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>427</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="52">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>428</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>52</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>428</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="53">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>429</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>53</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>429</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="54">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>430</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>54</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>430</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="55">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>431</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>55</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>431</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="56">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>432</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>56</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>432</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="57">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>433</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>57</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>433</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="58">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>434</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>58</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>434</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="59">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>435</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>59</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>435</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="60">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>436</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>60</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>436</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="61">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>437</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>61</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>437</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="62">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>438</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>62</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>438</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="63">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>439</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>63</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>439</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="64">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>440</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>64</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>440</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="65">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>441</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>65</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>441</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="66">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>442</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>66</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>442</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="67">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>443</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>67</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>443</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="68">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>444</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>68</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>444</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="69">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>445</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>69</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>445</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="70">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>446</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>70</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>446</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="71">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>447</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>71</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>447</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="72">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>448</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>72</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>448</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="73">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>449</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>73</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>449</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="74">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>450</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>74</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>450</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="75">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>451</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>75</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>451</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="76">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>452</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>76</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>452</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="77">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>453</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>77</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>453</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="78">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>454</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>78</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>454</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="79">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>455</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>79</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>455</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="80">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>456</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>80</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>456</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="81">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>457</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>81</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>457</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="82">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>458</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>82</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>458</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="83">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>459</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>83</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>459</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="84">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>460</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>84</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>460</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="85">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>461</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>85</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>461</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="86">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>462</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>86</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>462</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="87">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>463</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>87</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>463</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="88">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>464</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>88</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>464</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="89">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>465</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>89</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>465</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="90">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>466</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>90</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>466</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="91">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>467</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>91</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>467</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="92">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>468</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>92</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>468</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="93">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>469</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>93</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>469</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="94">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>470</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>94</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>470</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="95">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>471</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>95</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>471</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="96">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>472</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>96</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>472</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="97">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>473</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>97</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>473</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="98">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>474</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>98</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>474</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="99">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>475</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>99</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>475</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="100">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>476</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>100</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>476</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="101">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>477</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>101</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>477</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="102">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>478</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>102</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>478</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="103">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>479</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>103</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>479</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="104">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>480</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>104</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>480</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="105">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>481</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>105</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>481</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="106">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>482</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>106</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>482</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="107">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>483</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>107</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>483</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="108">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>484</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>108</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>484</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="109">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>485</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>109</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>485</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="110">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>486</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>110</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>486</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="111">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>487</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>111</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>487</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="112">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>488</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>112</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>488</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="113">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>489</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>113</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>489</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="114">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>490</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>114</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>490</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="115">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>491</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>115</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>491</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="116">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>492</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>116</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>492</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="117">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>493</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>117</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>493</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="118">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>494</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>118</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>494</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="119">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>495</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>119</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>495</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="120">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>496</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>120</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>496</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="121">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>497</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>121</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>497</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="122">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>498</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>122</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>498</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="123">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>499</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>123</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>499</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="124">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>500</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>124</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>500</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="125">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>501</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>125</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>501</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="126">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>502</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>126</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>502</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="127">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>503</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>127</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>503</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="128">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>504</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>128</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>504</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="129">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>505</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>129</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>505</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="130">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>506</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>130</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>506</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="131">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>507</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>131</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>507</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="132">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>508</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>132</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>508</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="133">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>509</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>133</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>509</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="134">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>510</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>134</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>510</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="135">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>511</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>135</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>511</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="136">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>512</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>136</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>512</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="137">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>513</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>137</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>513</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="138">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>514</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>138</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>514</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="139">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>515</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>139</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>515</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="140">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>516</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>140</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>516</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="141">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>517</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>141</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>517</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="142">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>518</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>142</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>518</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="143">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>519</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>143</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>519</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="144">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>520</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>144</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>520</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="145">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>521</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>145</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>521</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="146">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>522</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>146</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>522</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="147">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>523</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>147</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>523</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="148">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>524</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>148</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>524</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="149">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>525</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>149</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>525</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="150">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>526</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>150</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>526</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="151">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>527</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>151</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>527</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="152">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>528</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>152</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>528</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="153">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>529</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>153</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>529</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="154">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>530</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>154</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>530</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="155">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>531</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>155</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>531</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="156">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>532</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>156</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>532</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="157">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>533</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>157</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>533</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="158">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>534</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>158</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>534</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="159">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>535</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>159</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>535</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="160">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>536</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>160</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>536</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="161">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>537</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>161</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>537</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="162">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>538</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>162</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>538</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="163">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>539</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>163</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>539</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="164">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>540</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>164</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>540</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="165">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>541</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>165</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>541</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="166">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>542</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>166</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>542</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="167">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>543</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>167</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>543</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="168">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>544</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>168</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>544</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="169">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>545</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>169</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>545</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="170">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>546</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>170</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>546</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="171">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>547</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>171</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>547</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="172">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>548</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>172</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>548</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="173">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>549</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>173</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>549</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="174">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>550</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>174</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>550</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="175">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>551</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>175</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>551</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="176">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>552</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>176</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>552</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="177">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>553</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>177</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>553</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="178">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>554</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>178</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>554</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="179">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>555</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>179</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>555</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="180">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>556</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>180</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>556</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="181">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>557</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>181</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>557</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="182">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>558</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>182</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>558</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="183">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>559</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>183</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>559</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="184">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>560</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>184</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>560</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="185">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>561</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>185</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>561</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="186">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>562</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>186</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>562</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="187">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>563</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>187</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>563</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="188">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>564</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>188</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>564</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="189">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>565</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>189</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>565</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="190">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>566</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>190</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>566</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="191">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>567</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>191</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>567</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="192">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>568</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>192</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>568</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="193">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>569</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>193</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>569</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="194">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>570</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>194</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>570</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="195">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>571</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>195</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>571</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="196">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>572</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>196</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>572</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="197">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>573</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>197</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>573</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="198">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>574</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>198</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>574</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="199">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>575</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>199</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>575</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="200">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>576</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>200</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>576</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="201">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>577</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>201</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>577</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="202">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>578</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>202</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>578</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="203">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>579</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>203</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>579</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="204">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>580</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>204</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>580</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="205">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>581</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>205</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>581</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="206">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>582</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>206</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>582</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="207">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>583</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>207</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>583</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="208">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>584</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>208</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>584</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="209">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>585</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>209</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>585</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="210">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>586</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>210</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>586</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="211">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>587</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>211</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>587</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="212">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>588</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>212</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>588</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="213">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>589</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>213</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>589</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="214">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>590</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>214</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>590</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="215">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>591</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>215</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>591</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="216">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>592</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>216</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>592</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="217">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>593</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>217</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>593</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="218">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>594</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>218</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>594</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="219">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>595</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>219</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>595</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="220">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>596</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>220</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>596</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="221">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>597</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>221</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>597</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="222">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>598</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>222</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>598</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="223">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>599</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>223</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>599</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="224">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>600</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>224</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>600</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="225">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>601</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>225</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>601</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="226">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>602</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>226</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>602</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="227">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>603</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>227</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>603</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="228">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>604</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>228</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>604</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="229">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>605</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>229</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>605</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="230">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>606</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>230</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>606</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="231">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>607</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>231</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>607</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="232">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>608</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>232</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>608</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="233">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>609</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>233</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>609</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="234">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>610</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>234</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>610</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="235">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>611</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>235</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>611</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="236">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>612</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>236</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>612</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="237">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>613</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>237</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>613</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="238">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>614</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>238</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>614</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="239">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>615</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>239</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>615</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="240">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>616</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>240</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>616</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="241">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>617</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>241</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>617</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="242">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>618</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>242</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>618</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="243">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>619</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>243</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>619</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="244">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>620</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>244</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>620</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="245">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>621</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>245</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>621</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="246">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>622</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>246</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>622</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="247">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>623</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>247</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>623</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="248">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>624</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>248</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>624</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="249">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>625</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>249</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>625</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="250">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>626</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>250</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>626</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="251">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>627</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>251</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>627</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="252">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>628</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>252</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>628</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="253">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>629</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>253</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>629</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="254">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>630</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>254</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>630</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="255">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>631</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>255</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>631</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="256">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>632</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>256</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>632</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="257">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>633</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>257</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>633</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="258">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>634</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>258</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>634</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="259">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>635</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>259</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>635</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="260">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>636</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>260</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>636</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="261">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>637</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>261</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>637</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="262">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>638</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>262</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>638</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="263">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>639</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>263</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>639</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="264">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>640</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>264</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>640</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="265">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>641</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>265</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>641</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="266">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>642</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>266</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>642</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="267">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>643</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>267</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>643</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="268">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>644</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>268</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>644</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="269">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>645</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>269</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>645</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="270">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>646</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>270</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>646</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="271">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>647</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>271</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>647</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="272">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>648</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>272</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>648</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="273">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>649</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>273</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>649</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="274">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>650</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>274</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>650</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="275">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>651</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>275</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>651</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="276">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>652</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>276</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>652</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="277">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>653</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>277</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>653</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="278">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>654</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>278</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>654</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="279">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>655</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>279</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>655</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="280">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>656</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>280</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>656</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="281">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>657</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>281</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>657</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="282">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>658</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>282</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>658</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="283">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>283</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>659</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_refine_tlsCategory>
      <PDBx:pdbx_refine_tls id="1">
         <PDBx:L11>0.0303</PDBx:L11>
         <PDBx:L12>0.1382</PDBx:L12>
         <PDBx:L13>-0.0005</PDBx:L13>
         <PDBx:L22>1.6669</PDBx:L22>
         <PDBx:L23>0.2230</PDBx:L23>
         <PDBx:L33>0.0826</PDBx:L33>
         <PDBx:S11>-0.0120</PDBx:S11>
         <PDBx:S12>0.0055</PDBx:S12>
         <PDBx:S13>-0.0102</PDBx:S13>
         <PDBx:S21>0.0078</PDBx:S21>
         <PDBx:S22>0.0357</PDBx:S22>
         <PDBx:S23>0.0402</PDBx:S23>
         <PDBx:S31>0.0248</PDBx:S31>
         <PDBx:S32>-0.0026</PDBx:S32>
         <PDBx:S33>-0.0237</PDBx:S33>
         <PDBx:T11>0.0429</PDBx:T11>
         <PDBx:T12>-0.0061</PDBx:T12>
         <PDBx:T13>-0.0009</PDBx:T13>
         <PDBx:T22>0.0022</PDBx:T22>
         <PDBx:T23>0.0048</PDBx:T23>
         <PDBx:T33>0.0613</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>19.1922</PDBx:origin_x>
         <PDBx:origin_y>-2.1949</PDBx:origin_y>
         <PDBx:origin_z>7.7244</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
      <PDBx:pdbx_refine_tls id="2">
         <PDBx:L11>0.2240</PDBx:L11>
         <PDBx:L12>0.0354</PDBx:L12>
         <PDBx:L13>-0.0842</PDBx:L13>
         <PDBx:L22>0.2149</PDBx:L22>
         <PDBx:L23>-0.0228</PDBx:L23>
         <PDBx:L33>0.4535</PDBx:L33>
         <PDBx:S11>0.0090</PDBx:S11>
         <PDBx:S12>-0.0103</PDBx:S12>
         <PDBx:S13>0.0360</PDBx:S13>
         <PDBx:S21>-0.0046</PDBx:S21>
         <PDBx:S22>0.0188</PDBx:S22>
         <PDBx:S23>0.0153</PDBx:S23>
         <PDBx:S31>-0.0211</PDBx:S31>
         <PDBx:S32>-0.0013</PDBx:S32>
         <PDBx:S33>-0.0278</PDBx:S33>
         <PDBx:T11>0.0174</PDBx:T11>
         <PDBx:T12>0.0031</PDBx:T12>
         <PDBx:T13>0.0013</PDBx:T13>
         <PDBx:T22>0.0084</PDBx:T22>
         <PDBx:T23>-0.0017</PDBx:T23>
         <PDBx:T33>0.0187</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>19.3565</PDBx:origin_x>
         <PDBx:origin_y>27.0111</PDBx:origin_y>
         <PDBx:origin_z>2.7863</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
      <PDBx:pdbx_refine_tls id="3">
         <PDBx:L11>3.7760</PDBx:L11>
         <PDBx:L12>-0.4882</PDBx:L12>
         <PDBx:L13>1.7529</PDBx:L13>
         <PDBx:L22>0.9291</PDBx:L22>
         <PDBx:L23>-1.2270</PDBx:L23>
         <PDBx:L33>2.0674</PDBx:L33>
         <PDBx:S11>-0.0234</PDBx:S11>
         <PDBx:S12>-0.0195</PDBx:S12>
         <PDBx:S13>-0.2341</PDBx:S13>
         <PDBx:S21>0.1207</PDBx:S21>
         <PDBx:S22>0.1411</PDBx:S22>
         <PDBx:S23>0.0369</PDBx:S23>
         <PDBx:S31>-0.0534</PDBx:S31>
         <PDBx:S32>-0.1859</PDBx:S32>
         <PDBx:S33>-0.1177</PDBx:S33>
         <PDBx:T11>0.1049</PDBx:T11>
         <PDBx:T12>0.0034</PDBx:T12>
         <PDBx:T13>0.0033</PDBx:T13>
         <PDBx:T22>0.0266</PDBx:T22>
         <PDBx:T23>-0.0008</PDBx:T23>
         <PDBx:T33>0.0210</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>16.8089</PDBx:origin_x>
         <PDBx:origin_y>4.9476</PDBx:origin_y>
         <PDBx:origin_z>19.7350</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
      <PDBx:pdbx_refine_tls id="4">
         <PDBx:L11>0.5453</PDBx:L11>
         <PDBx:L12>1.0436</PDBx:L12>
         <PDBx:L13>0.8859</PDBx:L13>
         <PDBx:L22>2.8488</PDBx:L22>
         <PDBx:L23>3.0589</PDBx:L23>
         <PDBx:L33>4.7977</PDBx:L33>
         <PDBx:S11>0.0116</PDBx:S11>
         <PDBx:S12>0.0084</PDBx:S12>
         <PDBx:S13>-0.0581</PDBx:S13>
         <PDBx:S21>0.0096</PDBx:S21>
         <PDBx:S22>0.0617</PDBx:S22>
         <PDBx:S23>-0.1443</PDBx:S23>
         <PDBx:S31>0.0053</PDBx:S31>
         <PDBx:S32>0.1249</PDBx:S32>
         <PDBx:S33>-0.0733</PDBx:S33>
         <PDBx:T11>0.0244</PDBx:T11>
         <PDBx:T12>0.0004</PDBx:T12>
         <PDBx:T13>0.0032</PDBx:T13>
         <PDBx:T22>0.0044</PDBx:T22>
         <PDBx:T23>-0.0018</PDBx:T23>
         <PDBx:T33>0.0181</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>29.2641</PDBx:origin_x>
         <PDBx:origin_y>3.8455</PDBx:origin_y>
         <PDBx:origin_z>7.1901</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
      <PDBx:pdbx_refine_tls id="5">
         <PDBx:L11>0.1820</PDBx:L11>
         <PDBx:L12>-0.0519</PDBx:L12>
         <PDBx:L13>0.1533</PDBx:L13>
         <PDBx:L22>0.3136</PDBx:L22>
         <PDBx:L23>-0.3122</PDBx:L23>
         <PDBx:L33>0.6967</PDBx:L33>
         <PDBx:S11>-0.0178</PDBx:S11>
         <PDBx:S12>-0.0214</PDBx:S12>
         <PDBx:S13>-0.0238</PDBx:S13>
         <PDBx:S21>0.0157</PDBx:S21>
         <PDBx:S22>0.0038</PDBx:S22>
         <PDBx:S23>-0.0105</PDBx:S23>
         <PDBx:S31>0.0222</PDBx:S31>
         <PDBx:S32>0.0040</PDBx:S32>
         <PDBx:S33>0.0140</PDBx:S33>
         <PDBx:T11>0.0251</PDBx:T11>
         <PDBx:T12>0.0028</PDBx:T12>
         <PDBx:T13>0.0023</PDBx:T13>
         <PDBx:T22>0.0116</PDBx:T22>
         <PDBx:T23>0.0012</PDBx:T23>
         <PDBx:T33>0.0119</PDBx:T33>
         <PDBx:method>refined</PDBx:method>
         <PDBx:origin_x>21.9755</PDBx:origin_x>
         <PDBx:origin_y>14.6900</PDBx:origin_y>
         <PDBx:origin_z>10.4414</PDBx:origin_z>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
      </PDBx:pdbx_refine_tls>
   </PDBx:pdbx_refine_tlsCategory>
   <PDBx:pdbx_refine_tls_groupCategory>
      <PDBx:pdbx_refine_tls_group id="1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>396</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>407</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>1</PDBx:refine_tls_id>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>453</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>476</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>1</PDBx:refine_tls_id>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>418</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>436</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>1</PDBx:refine_tls_id>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="4">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>477</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>514</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>2</PDBx:refine_tls_id>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="5">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>559</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>658</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>2</PDBx:refine_tls_id>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="6">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>437</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>452</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>3</PDBx:refine_tls_id>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="7">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>408</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>417</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>4</PDBx:refine_tls_id>
      </PDBx:pdbx_refine_tls_group>
      <PDBx:pdbx_refine_tls_group id="8">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_seq_id>515</PDBx:beg_auth_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_seq_id>558</PDBx:end_auth_seq_id>
         <PDBx:pdbx_refine_id>X-RAY DIFFRACTION</PDBx:pdbx_refine_id>
         <PDBx:refine_tls_id>5</PDBx:refine_tls_id>
      </PDBx:pdbx_refine_tls_group>
   </PDBx:pdbx_refine_tls_groupCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_and_software_defined_assembly</PDBx:details>
         <PDBx:method_details>PISA</PDBx:method_details>
         <PDBx:oligomeric_count>1</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>monomeric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B,C,D,E" oper_expression="1"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:symmetry_operation>x,y,z</PDBx:symmetry_operation>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_struct_sheet_hbondCategory>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="A">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>LYS</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>406</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>LYS</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>30</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>TYR</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>418</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>TYR</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>42</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="2" range_id_2="3" sheet_id="A">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>VAL</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>415</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>VAL</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>39</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>MET</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>431</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>MET</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>55</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="3" range_id_2="4" sheet_id="A">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>LYS</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>430</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>LYS</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>54</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ILE</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>472</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ILE</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>96</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="4" range_id_2="5" sheet_id="A">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>ILE</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>473</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>ILE</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>97</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>TYR</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>461</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>TYR</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>85</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="B">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>LEU</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>528</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>LEU</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>152</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LYS</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>536</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LYS</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>160</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
   </PDBx:pdbx_struct_sheet_hbondCategory>
   <PDBx:pdbx_unobs_or_zero_occ_residuesCategory>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>377</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>378</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>2</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>379</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_seq_id>3</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>380</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_seq_id>4</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>381</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>5</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>382</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>6</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>383</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>7</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>8</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>385</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>PRO</PDBx:label_comp_id>
         <PDBx:label_seq_id>9</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>386</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>10</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>387</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_seq_id>11</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>12</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="13">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>389</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>13</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="14">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>390</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>14</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="15">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>391</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>15</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="16">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>392</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>16</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="17">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>393</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>17</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="18">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>394</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>18</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="19">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>395</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_seq_id>19</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="20">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>659</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>283</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
   </PDBx:pdbx_unobs_or_zero_occ_residuesCategory>
   <PDBx:pdbx_validate_close_contactCategory>
      <PDBx:pdbx_validate_close_contact id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1137</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>1229</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1020</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>1301</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>396</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>1249</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
   </PDBx:pdbx_validate_close_contactCategory>
   <PDBx:pdbx_validate_rmsd_angleCategory>
      <PDBx:pdbx_validate_rmsd_angle id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-3.06</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>120.30</PDBx:angle_target_value>
         <PDBx:angle_value>117.24</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>NE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NH2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ARG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>487</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>487</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>487</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>10.22</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.70</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.00</PDBx:angle_target_value>
         <PDBx:angle_value>121.22</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CD1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>586</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>586</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>586</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
   </PDBx:pdbx_validate_rmsd_angleCategory>
   <PDBx:pdbx_validate_rmsd_bondCategory>
      <PDBx:pdbx_validate_rmsd_bond id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>SG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>481</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>481</PDBx:auth_seq_id_2>
         <PDBx:bond_deviation>-0.101</PDBx:bond_deviation>
         <PDBx:bond_standard_deviation>0.016</PDBx:bond_standard_deviation>
         <PDBx:bond_target_value>1.812</PDBx:bond_target_value>
         <PDBx:bond_value>1.711</PDBx:bond_value>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_bond>
      <PDBx:pdbx_validate_rmsd_bond id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>488</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>488</PDBx:auth_seq_id_2>
         <PDBx:bond_deviation>0.088</PDBx:bond_deviation>
         <PDBx:bond_standard_deviation>0.011</PDBx:bond_standard_deviation>
         <PDBx:bond_target_value>1.252</PDBx:bond_target_value>
         <PDBx:bond_value>1.340</PDBx:bond_value>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_bond>
      <PDBx:pdbx_validate_rmsd_bond id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>513</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>513</PDBx:auth_seq_id_2>
         <PDBx:bond_deviation>0.094</PDBx:bond_deviation>
         <PDBx:bond_standard_deviation>0.015</PDBx:bond_standard_deviation>
         <PDBx:bond_target_value>1.515</PDBx:bond_target_value>
         <PDBx:bond_value>1.609</PDBx:bond_value>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_bond>
      <PDBx:pdbx_validate_rmsd_bond id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>513</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>513</PDBx:auth_seq_id_2>
         <PDBx:bond_deviation>0.122</PDBx:bond_deviation>
         <PDBx:bond_standard_deviation>0.011</PDBx:bond_standard_deviation>
         <PDBx:bond_target_value>1.252</PDBx:bond_target_value>
         <PDBx:bond_value>1.374</PDBx:bond_value>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_bond>
   </PDBx:pdbx_validate_rmsd_bondCategory>
   <PDBx:pdbx_validate_symm_contactCategory>
      <PDBx:pdbx_validate_symm_contact id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>444</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>532</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>1_556</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
   </PDBx:pdbx_validate_symm_contactCategory>
   <PDBx:pdbx_validate_torsionCategory>
      <PDBx:pdbx_validate_torsion id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>424</PDBx:auth_seq_id>
         <PDBx:phi>-141.82</PDBx:phi>
         <PDBx:psi>-44.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>466</PDBx:auth_seq_id>
         <PDBx:phi>-95.54</PDBx:phi>
         <PDBx:psi>39.65</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>520</PDBx:auth_seq_id>
         <PDBx:phi>73.97</PDBx:phi>
         <PDBx:psi>-6.47</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>521</PDBx:auth_seq_id>
         <PDBx:phi>-144.92</PDBx:phi>
         <PDBx:psi>49.40</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>547</PDBx:auth_seq_id>
         <PDBx:phi>-106.48</PDBx:phi>
         <PDBx:psi>78.06</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
   </PDBx:pdbx_validate_torsionCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="4OT5" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:B_iso_mean>23.188</PDBx:B_iso_mean>
         <PDBx:aniso_B11>0.39</PDBx:aniso_B11>
         <PDBx:aniso_B12>0.00</PDBx:aniso_B12>
         <PDBx:aniso_B13>-0.00</PDBx:aniso_B13>
         <PDBx:aniso_B22>0.60</PDBx:aniso_B22>
         <PDBx:aniso_B23>-0.00</PDBx:aniso_B23>
         <PDBx:aniso_B33>-0.99</PDBx:aniso_B33>
         <PDBx:correlation_coeff_Fo_to_Fc>0.972</PDBx:correlation_coeff_Fo_to_Fc>
         <PDBx:correlation_coeff_Fo_to_Fc_free>0.954</PDBx:correlation_coeff_Fo_to_Fc_free>
         <PDBx:ls_R_factor_R_free>0.19352</PDBx:ls_R_factor_R_free>
         <PDBx:ls_R_factor_R_work>0.14053</PDBx:ls_R_factor_R_work>
         <PDBx:ls_R_factor_obs>0.14319</PDBx:ls_R_factor_obs>
         <PDBx:ls_d_res_high>1.55</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>38.38</PDBx:ls_d_res_low>
         <PDBx:ls_number_reflns_R_free>2138</PDBx:ls_number_reflns_R_free>
         <PDBx:ls_number_reflns_obs>40425</PDBx:ls_number_reflns_obs>
         <PDBx:ls_percent_reflns_R_free>5.0</PDBx:ls_percent_reflns_R_free>
         <PDBx:ls_percent_reflns_obs>98.11</PDBx:ls_percent_reflns_obs>
         <PDBx:overall_SU_B>2.770</PDBx:overall_SU_B>
         <PDBx:overall_SU_ML>0.045</PDBx:overall_SU_ML>
         <PDBx:pdbx_R_Free_selection_details>RANDOM</PDBx:pdbx_R_Free_selection_details>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_ls_cross_valid_method>THROUGHOUT</PDBx:pdbx_ls_cross_valid_method>
         <PDBx:pdbx_method_to_determine_struct>FOURIER SYNTHESIS</PDBx:pdbx_method_to_determine_struct>
         <PDBx:pdbx_overall_ESU_R>0.083</PDBx:pdbx_overall_ESU_R>
         <PDBx:pdbx_overall_ESU_R_Free>0.076</PDBx:pdbx_overall_ESU_R_Free>
         <PDBx:pdbx_solvent_ion_probe_radii>0.80</PDBx:pdbx_solvent_ion_probe_radii>
         <PDBx:pdbx_solvent_shrinkage_radii>0.80</PDBx:pdbx_solvent_shrinkage_radii>
         <PDBx:pdbx_solvent_vdw_probe_radii>1.20</PDBx:pdbx_solvent_vdw_probe_radii>
         <PDBx:pdbx_starting_model>PDB ENTRY 3PIX</PDBx:pdbx_starting_model>
         <PDBx:pdbx_stereochemistry_target_values>MAXIMUM LIKELIHOOD</PDBx:pdbx_stereochemistry_target_values>
         <PDBx:solvent_model_details>MASK</PDBx:solvent_model_details>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="LAST" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>1.55</PDBx:d_res_high>
         <PDBx:d_res_low>38.38</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>301</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>2492</PDBx:number_atoms_total>
         <PDBx:pdbx_number_atoms_ligand>52</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>0</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>2139</PDBx:pdbx_number_atoms_protein>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_bond_refined_d">
         <PDBx:dev_ideal>0.021</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.019</PDBx:dev_ideal_target>
         <PDBx:number>2244</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_bond_other_d">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_angle_refined_deg">
         <PDBx:dev_ideal>1.908</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>1.986</PDBx:dev_ideal_target>
         <PDBx:number>3030</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_angle_other_deg">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_1_deg">
         <PDBx:dev_ideal>5.931</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>5.000</PDBx:dev_ideal_target>
         <PDBx:number>262</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_2_deg">
         <PDBx:dev_ideal>34.604</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>24.135</PDBx:dev_ideal_target>
         <PDBx:number>104</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_3_deg">
         <PDBx:dev_ideal>11.913</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>15.000</PDBx:dev_ideal_target>
         <PDBx:number>401</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_dihedral_angle_4_deg">
         <PDBx:dev_ideal>13.507</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>15.000</PDBx:dev_ideal_target>
         <PDBx:number>12</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_chiral_restr">
         <PDBx:dev_ideal>0.157</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.200</PDBx:dev_ideal_target>
         <PDBx:number>320</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_gen_planes_refined">
         <PDBx:dev_ideal>0.012</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.021</PDBx:dev_ideal_target>
         <PDBx:number>1692</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_gen_planes_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_nbd_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_nbd_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_nbtor_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_nbtor_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_xyhbond_nbd_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_xyhbond_nbd_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_metal_ion_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_metal_ion_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_vdw_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_vdw_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_hbond_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_hbond_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_metal_ion_refined">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_symmetry_metal_ion_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcbond_it">
         <PDBx:dev_ideal>2.043</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>1.590</PDBx:dev_ideal_target>
         <PDBx:number>1051</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcbond_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcangle_it">
         <PDBx:dev_ideal>2.331</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>2.385</PDBx:dev_ideal_target>
         <PDBx:number>1312</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_mcangle_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_scbond_it">
         <PDBx:dev_ideal>3.959</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>1.964</PDBx:dev_ideal_target>
         <PDBx:number>1193</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_scbond_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_scangle_it">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_scangle_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_long_range_B_refined">
         <PDBx:dev_ideal>4.149</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>16.001</PDBx:dev_ideal_target>
         <PDBx:number>3814</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_long_range_B_other">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_rigid_bond_restr">
         <PDBx:dev_ideal>7.004</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>3.000</PDBx:dev_ideal_target>
         <PDBx:number>2244</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_sphericity_free">
         <PDBx:dev_ideal>27.993</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>5.000</PDBx:dev_ideal_target>
         <PDBx:number>85</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="r_sphericity_bonded">
         <PDBx:dev_ideal>10.764</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>5.000</PDBx:dev_ideal_target>
         <PDBx:number>2408</PDBx:number>
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:refine_ls_shellCategory>
      <PDBx:refine_ls_shell d_res_high="1.55" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.248</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_work>0.204</PDBx:R_factor_R_work>
         <PDBx:d_res_low>1.591</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>131</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2570</PDBx:number_reflns_R_work>
         <PDBx:pdbx_total_number_of_bins_used>20</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_obs>85.21</PDBx:percent_reflns_obs>
      </PDBx:refine_ls_shell>
   </PDBx:refine_ls_shellCategory>
   <PDBx:reflnsCategory>
      <PDBx:reflns pdbx_ordinal="1">
         <PDBx:B_iso_Wilson_estimate>19.8</PDBx:B_iso_Wilson_estimate>
         <PDBx:d_resolution_high>1.55</PDBx:d_resolution_high>
         <PDBx:d_resolution_low>40.00</PDBx:d_resolution_low>
         <PDBx:entry_id>4OT5</PDBx:entry_id>
         <PDBx:number_obs>42617</PDBx:number_obs>
         <PDBx:pdbx_Rsym_value>0.078</PDBx:pdbx_Rsym_value>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_netI_over_sigmaI>16.4</PDBx:pdbx_netI_over_sigmaI>
         <PDBx:pdbx_redundancy>4.9</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_obs>98.4</PDBx:percent_possible_obs>
      </PDBx:reflns>
   </PDBx:reflnsCategory>
   <PDBx:reflns_shellCategory>
      <PDBx:reflns_shell pdbx_ordinal="1">
         <PDBx:d_res_high>1.55</PDBx:d_res_high>
         <PDBx:d_res_low>1.59</PDBx:d_res_low>
         <PDBx:meanI_over_sigI_obs>2.6</PDBx:meanI_over_sigI_obs>
         <PDBx:number_unique_all>2705</PDBx:number_unique_all>
         <PDBx:pdbx_Rsym_value>0.381</PDBx:pdbx_Rsym_value>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>3.2</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_all>85.2</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
   </PDBx:reflns_shellCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>REFMAC</PDBx:name>
         <PDBx:version>5.8.0048</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="2">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>CNS</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="3">
         <PDBx:classification>data collection</PDBx:classification>
         <PDBx:name>ADSC</PDBx:name>
         <PDBx:version>Quantum</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="4">
         <PDBx:classification>data reduction</PDBx:classification>
         <PDBx:name>DENZO</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="5">
         <PDBx:classification>data scaling</PDBx:classification>
         <PDBx:name>SCALEPACK</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="6">
         <PDBx:classification>phasing</PDBx:classification>
         <PDBx:name>CNS</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="4OT5">
         <PDBx:pdbx_descriptor>Tyrosine-protein kinase BTK (E.C.2.7.10.2)</PDBx:pdbx_descriptor>
         <PDBx:title>Crystal structure of BTK kinase domain complexed with 4-tert-Butyl-N-(3-{8-[4-(4-methyl-piperazine-1-carbonyl)-phenylamino]-imidazo[1,2-a]pyrazin-6-yl}-phenyl)-benzamide</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="C">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="D">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="E">
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_biolCategory>
      <PDBx:struct_biol id="1">
      </PDBx:struct_biol>
   </PDBx:struct_biolCategory>
   <PDBx:struct_confCategory>
      <PDBx:struct_conf id="HELX_P1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>398</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>22</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>400</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>24</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>1</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>3</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>438</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>62</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>MET</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>450</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>MET</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>74</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>2</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>13</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>CYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>481</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>CYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>105</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>488</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>112</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>3</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>8</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P4">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ALA</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>489</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ALA</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>113</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>492</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>116</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>4</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>4</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P5">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>494</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>118</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>515</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>139</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>5</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>22</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P6">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ALA</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>523</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ALA</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>147</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ARG</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>525</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ARG</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>149</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>6</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>3</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P7">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLY</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>541</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLY</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>165</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>546</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>170</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>7</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P8">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>548</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>172</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>553</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>177</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>8</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P9">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PRO</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>560</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PRO</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>184</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>564</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>188</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>9</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>5</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P10">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PRO</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>565</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PRO</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>189</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>572</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>196</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>10</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>8</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P11">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>575</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>199</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>592</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>216</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>11</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>18</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P12">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>602</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>226</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>612</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>236</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>12</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>11</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P13">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>623</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>247</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>CYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>633</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>CYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>257</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>13</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>11</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P14">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>637</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>261</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ARG</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>641</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ARG</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>265</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>14</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>5</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P15">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>643</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>267</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>658</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>282</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>15</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>16</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
   </PDBx:struct_confCategory>
   <PDBx:struct_conf_typeCategory>
      <PDBx:struct_conf_type id="HELX_P">
      </PDBx:struct_conf_type>
   </PDBx:struct_conf_typeCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="4OT5">
         <PDBx:pdbx_keywords>TRANSFERASE/TRANSFERASE INHIBITOR</PDBx:pdbx_keywords>
         <PDBx:text>TRANSFERASE-TRANSFERASE INHIBITOR complex</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_mon_prot_cisCategory>
      <PDBx:struct_mon_prot_cis pdbx_id="1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>468</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>92</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>469</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>93</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>4.88</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
   </PDBx:struct_mon_prot_cisCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:db_code>BTK_HUMAN</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>378</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>Q06187</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>SQQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEGSMSEDEFIEEAKVMMNLSHEKL
VQLYGVCTKQRPIFIITEYMANGCLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKV
SDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYERFTNSETAEHIAQGLRLY
RPHLASEKVYTIMYSCWHEKADERPTFKILLSNILDVMDEES</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>378</PDBx:db_align_beg>
         <PDBx:db_align_end>659</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>4OT5</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>378</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>659</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>Q06187</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>2</PDBx:seq_align_beg>
         <PDBx:seq_align_end>283</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_ref_seq_difCategory>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="1">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:details>EXPRESSION TAG</PDBx:details>
         <PDBx:mon_id>GLY</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>377</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>4OT5</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>Q06187</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:seq_num>1</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="2">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>MET</PDBx:db_mon_id>
         <PDBx:details>ENGINEERED MUTATION</PDBx:details>
         <PDBx:mon_id>ALA</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>489</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>4OT5</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>Q06187</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>489</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>113</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="3">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>ARG</PDBx:db_mon_id>
         <PDBx:details>ENGINEERED MUTATION</PDBx:details>
         <PDBx:mon_id>ALA</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>492</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>4OT5</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>Q06187</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>492</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>116</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="4">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>GLU</PDBx:db_mon_id>
         <PDBx:details>ENGINEERED MUTATION</PDBx:details>
         <PDBx:mon_id>ALA</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>624</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>4OT5</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>Q06187</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>624</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>248</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="5">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>LYS</PDBx:db_mon_id>
         <PDBx:details>ENGINEERED MUTATION</PDBx:details>
         <PDBx:mon_id>ALA</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>625</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>4OT5</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>Q06187</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>625</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>249</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
   </PDBx:struct_ref_seq_difCategory>
   <PDBx:struct_sheetCategory>
      <PDBx:struct_sheet id="A">
         <PDBx:number_strands>5</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="B">
         <PDBx:number_strands>2</PDBx:number_strands>
      </PDBx:struct_sheet>
   </PDBx:struct_sheetCategory>
   <PDBx:struct_sheet_orderCategory>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="3" range_id_2="4" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="4" range_id_2="5" sheet_id="A">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="B">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
   </PDBx:struct_sheet_orderCategory>
   <PDBx:struct_sheet_rangeCategory>
      <PDBx:struct_sheet_range id="1" sheet_id="A">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LEU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>402</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LEU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>26</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>411</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>35</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="A">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLY</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>414</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLY</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>38</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>TRP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>421</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>TRP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>45</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="A">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>TYR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>425</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>TYR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>49</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>MET</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>431</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>MET</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>55</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="4" sheet_id="A">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PHE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>471</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PHE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>95</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>475</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>99</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="5" sheet_id="A">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LEU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>460</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LEU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>84</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>CYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>464</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>CYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>88</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="B">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>CYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>527</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>CYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>151</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>529</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>153</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="B">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>VAL</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>535</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>VAL</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>159</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>537</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>161</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
   </PDBx:struct_sheet_rangeCategory>
   <PDBx:struct_siteCategory>
      <PDBx:struct_site id="AC1">
         <PDBx:details>BINDING SITE FOR RESIDUE 481 A 701</PDBx:details>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>19</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC2">
         <PDBx:details>BINDING SITE FOR RESIDUE DMS A 702</PDBx:details>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>6</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC3">
         <PDBx:details>BINDING SITE FOR RESIDUE DMS A 703</PDBx:details>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>5</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
   </PDBx:struct_siteCategory>
   <PDBx:struct_site_genCategory>
      <PDBx:struct_site_gen id="1" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>416</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_seq_id>40</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="2" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>428</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>52</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="3" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>430</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>54</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="4" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>474</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_seq_id>98</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="5" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>475</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="6" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>476</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>100</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="7" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>477</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>101</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="8" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>478</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>102</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="9" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>479</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>103</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="10" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>480</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>104</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="11" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>488</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>112</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="12" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>526</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>150</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="13" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>528</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>152</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="14" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>539</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>163</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="15" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>551</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>175</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="16" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>1005</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="17" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>1012</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="18" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>1155</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="19" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>1263</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>19</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="20" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>520</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>144</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="21" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TRP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>563</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>TRP</PDBx:label_comp_id>
         <PDBx:label_seq_id>187</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="22" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>564</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>188</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="23" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>578</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>202</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="24" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>1008</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="25" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>1016</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>6</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="26" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>492</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>116</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>5</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_556</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="27" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>520</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>144</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>5</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="28" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>551</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>175</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>5</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="29" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>559</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_seq_id>183</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>5</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="30" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>1032</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>5</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
   </PDBx:struct_site_genCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="4OT5">
         <PDBx:Int_Tables_number>18</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>P 21 21 2</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
