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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>98</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>98</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>98</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
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      <PDBx:atom_site id="715">
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>98</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
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      <PDBx:atom_site id="716">
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         <PDBx:Cartn_y>30.070</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.993</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>99</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="717">
         <PDBx:B_iso_or_equiv>17.07</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>29.370</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.922</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>99</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="718">
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         <PDBx:Cartn_y>30.364</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.228</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>99</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
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      <PDBx:atom_site id="719">
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         <PDBx:Cartn_y>31.597</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.406</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>99</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="720">
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         <PDBx:Cartn_z>6.989</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>99</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>6.021</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>99</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="722">
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         <PDBx:Cartn_y>28.897</PDBx:Cartn_y>
         <PDBx:Cartn_z>5.121</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>99</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>29.863</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.373</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>99</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>99</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="725">
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         <PDBx:Cartn_x>5.887</PDBx:Cartn_x>
         <PDBx:Cartn_y>28.197</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.167</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>99</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="726">
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         <PDBx:Cartn_x>5.530</PDBx:Cartn_x>
         <PDBx:Cartn_y>30.292</PDBx:Cartn_y>
         <PDBx:Cartn_z>3.268</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>99</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="727">
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         <PDBx:Cartn_y>29.812</PDBx:Cartn_y>
         <PDBx:Cartn_z>6.421</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>100</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>100</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>106</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>106</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>106</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>106</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_z>4.641</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>106</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>106</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="782">
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         <PDBx:Cartn_y>24.651</PDBx:Cartn_y>
         <PDBx:Cartn_z>4.481</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>106</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="783">
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         <PDBx:Cartn_z>3.805</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>106</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="784">
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         <PDBx:Cartn_y>28.840</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.125</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>107</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="785">
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         <PDBx:Cartn_y>29.251</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.421</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>107</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
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         <PDBx:Cartn_z>11.966</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>107</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>108</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>112</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>112</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>112</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>112</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>112</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>112</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>112</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_z>10.814</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>112</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>11.069</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>112</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="835">
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         <PDBx:Cartn_z>16.828</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>113</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>17.129</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>113</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>113</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>113</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>113</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:Cartn_z>16.008</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>113</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>113</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>145</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>145</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>145</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>145</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>145</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>145</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>145</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>145</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>145</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OH</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>145</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OH</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>156</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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      <PDBx:atom_site id="1181">
         <PDBx:B_iso_or_equiv>14.28</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>5.350</PDBx:Cartn_y>
         <PDBx:Cartn_z>24.930</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>156</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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      <PDBx:atom_site id="1182">
         <PDBx:B_iso_or_equiv>13.56</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_z>25.931</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>156</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1183">
         <PDBx:B_iso_or_equiv>13.55</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>9.395</PDBx:Cartn_y>
         <PDBx:Cartn_z>23.115</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>157</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>157</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1184">
         <PDBx:B_iso_or_equiv>13.68</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>13.675</PDBx:Cartn_x>
         <PDBx:Cartn_y>9.685</PDBx:Cartn_y>
         <PDBx:Cartn_z>22.664</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>157</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>157</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1185">
         <PDBx:B_iso_or_equiv>13.24</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>13.577</PDBx:Cartn_x>
         <PDBx:Cartn_y>11.002</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.943</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>157</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>157</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1186">
         <PDBx:B_iso_or_equiv>13.98</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>12.450</PDBx:Cartn_x>
         <PDBx:Cartn_y>11.483</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.686</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>157</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>157</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="1187">
         <PDBx:B_iso_or_equiv>15.46</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>12.807</PDBx:Cartn_x>
         <PDBx:Cartn_y>9.653</PDBx:Cartn_y>
         <PDBx:Cartn_z>23.949</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>157</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>157</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1188">
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         <PDBx:Cartn_x>12.223</PDBx:Cartn_x>
         <PDBx:Cartn_y>8.263</PDBx:Cartn_y>
         <PDBx:Cartn_z>24.175</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>157</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>157</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1189">
         <PDBx:B_iso_or_equiv>17.05</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.009</PDBx:Cartn_x>
         <PDBx:Cartn_y>8.444</PDBx:Cartn_y>
         <PDBx:Cartn_z>25.037</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>157</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>157</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1190">
         <PDBx:B_iso_or_equiv>17.00</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.400</PDBx:Cartn_x>
         <PDBx:Cartn_y>8.156</PDBx:Cartn_y>
         <PDBx:Cartn_z>26.439</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>157</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>157</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1191">
         <PDBx:B_iso_or_equiv>17.38</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.750</PDBx:Cartn_x>
         <PDBx:Cartn_y>8.854</PDBx:Cartn_y>
         <PDBx:Cartn_z>27.374</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>157</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>157</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1192">
         <PDBx:B_iso_or_equiv>18.42</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.820</PDBx:Cartn_x>
         <PDBx:Cartn_y>9.739</PDBx:Cartn_y>
         <PDBx:Cartn_z>26.988</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>157</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>157</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1193">
         <PDBx:B_iso_or_equiv>18.09</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.992</PDBx:Cartn_x>
         <PDBx:Cartn_y>8.589</PDBx:Cartn_y>
         <PDBx:Cartn_z>28.643</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>157</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>157</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1194">
         <PDBx:B_iso_or_equiv>11.87</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.725</PDBx:Cartn_x>
         <PDBx:Cartn_y>11.634</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.704</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>158</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>158</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1195">
         <PDBx:B_iso_or_equiv>9.10</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.759</PDBx:Cartn_x>
         <PDBx:Cartn_y>12.942</PDBx:Cartn_y>
         <PDBx:Cartn_z>21.012</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>158</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>158</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1196">
         <PDBx:B_iso_or_equiv>9.52</PDBx:B_iso_or_equiv>
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         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>168</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>168</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>168</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>168</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1265">
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         <PDBx:Cartn_z>-1.173</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>169</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>169</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1266">
         <PDBx:B_iso_or_equiv>11.21</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>14.355</PDBx:Cartn_y>
         <PDBx:Cartn_z>-2.198</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>169</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>169</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1267">
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         <PDBx:Cartn_y>13.912</PDBx:Cartn_y>
         <PDBx:Cartn_z>-2.931</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>169</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>169</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>13.829</PDBx:Cartn_y>
         <PDBx:Cartn_z>-4.169</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>169</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>169</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:Cartn_z>-1.583</PDBx:Cartn_z>
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>169</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>-1.122</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>169</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_y>17.908</PDBx:Cartn_y>
         <PDBx:Cartn_z>-0.801</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>169</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>18.803</PDBx:Cartn_y>
         <PDBx:Cartn_z>-0.797</PDBx:Cartn_z>
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>169</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>169</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>169</PDBx:label_seq_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:Cartn_y>20.096</PDBx:Cartn_y>
         <PDBx:Cartn_z>0.226</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>169</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_z>1.459</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>169</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:Cartn_x>20.772</PDBx:Cartn_x>
         <PDBx:Cartn_y>13.425</PDBx:Cartn_y>
         <PDBx:Cartn_z>-2.096</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>170</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>171</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:Cartn_z>0.063</PDBx:Cartn_z>
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         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>171</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:Cartn_z>-0.576</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>171</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:Cartn_z>1.437</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>171</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:Cartn_z>-5.014</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>172</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:Cartn_z>-6.207</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>172</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:Cartn_z>-7.340</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>172</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:Cartn_z>-8.483</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>172</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
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         <PDBx:Cartn_z>-5.993</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>172</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:Cartn_z>-7.277</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>172</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>172</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
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         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
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         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site id="1970">
         <PDBx:B_iso_or_equiv>12.78</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.636</PDBx:Cartn_x>
         <PDBx:Cartn_y>3.439</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.452</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>259</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1971">
         <PDBx:B_iso_or_equiv>13.20</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.639</PDBx:Cartn_x>
         <PDBx:Cartn_y>2.681</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.226</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>259</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1972">
         <PDBx:B_iso_or_equiv>12.60</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.299</PDBx:Cartn_x>
         <PDBx:Cartn_y>2.646</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.707</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>259</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1973">
         <PDBx:B_iso_or_equiv>12.27</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.484</PDBx:Cartn_x>
         <PDBx:Cartn_y>1.614</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.361</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>259</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1974">
         <PDBx:B_iso_or_equiv>12.54</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>12.098</PDBx:Cartn_x>
         <PDBx:Cartn_y>3.284</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.084</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>259</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1975">
         <PDBx:B_iso_or_equiv>12.52</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>12.366</PDBx:Cartn_x>
         <PDBx:Cartn_y>3.209</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.655</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OG1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>259</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OG1</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1976">
         <PDBx:B_iso_or_equiv>13.76</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>13.173</PDBx:Cartn_x>
         <PDBx:Cartn_y>2.528</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.896</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>259</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG2</PDBx:label_atom_id>
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>259</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1977">
         <PDBx:B_iso_or_equiv>12.48</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.777</PDBx:Cartn_x>
         <PDBx:Cartn_y>3.754</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.219</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>260</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1978">
         <PDBx:B_iso_or_equiv>12.28</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.444</PDBx:Cartn_x>
         <PDBx:Cartn_y>3.861</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.646</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>260</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1979">
         <PDBx:B_iso_or_equiv>13.22</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.169</PDBx:Cartn_x>
         <PDBx:Cartn_y>3.074</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.000</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>260</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1980">
         <PDBx:B_iso_or_equiv>12.68</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.232</PDBx:Cartn_x>
         <PDBx:Cartn_y>2.134</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.825</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>260</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1981">
         <PDBx:B_iso_or_equiv>12.69</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>9.387</PDBx:Cartn_x>
         <PDBx:Cartn_y>5.360</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.046</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>260</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="1982">
         <PDBx:B_iso_or_equiv>13.14</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>10.843</PDBx:Cartn_x>
         <PDBx:Cartn_y>5.911</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.918</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>260</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1983">
         <PDBx:B_iso_or_equiv>12.91</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>8.773</PDBx:Cartn_x>
         <PDBx:Cartn_y>5.603</PDBx:Cartn_y>
         <PDBx:Cartn_z>16.454</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>260</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1984">
         <PDBx:B_iso_or_equiv>14.34</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.085</PDBx:Cartn_x>
         <PDBx:Cartn_y>7.284</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.590</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>260</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>260</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site id="1985">
         <PDBx:B_iso_or_equiv>12.50</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>7.096</PDBx:Cartn_x>
         <PDBx:Cartn_y>3.431</PDBx:Cartn_y>
         <PDBx:Cartn_z>14.335</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>261</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>261</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site id="1986">
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         <PDBx:label_atom_id>O</PDBx:label_atom_id>
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         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
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         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>265</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2019">
         <PDBx:B_iso_or_equiv>14.02</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.392</PDBx:Cartn_x>
         <PDBx:Cartn_y>-1.192</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.357</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>265</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2020">
         <PDBx:B_iso_or_equiv>14.06</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.124</PDBx:Cartn_x>
         <PDBx:Cartn_y>-0.875</PDBx:Cartn_y>
         <PDBx:Cartn_z>12.043</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>265</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2021">
         <PDBx:B_iso_or_equiv>12.91</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>17.095</PDBx:Cartn_x>
         <PDBx:Cartn_y>-1.614</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.775</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>265</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2022">
         <PDBx:B_iso_or_equiv>14.13</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.868</PDBx:Cartn_x>
         <PDBx:Cartn_y>-2.563</PDBx:Cartn_y>
         <PDBx:Cartn_z>13.895</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>265</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2023">
         <PDBx:B_iso_or_equiv>14.50</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.341</PDBx:Cartn_x>
         <PDBx:Cartn_y>-2.815</PDBx:Cartn_y>
         <PDBx:Cartn_z>15.606</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>SG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>CYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>265</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>SG</PDBx:label_atom_id>
         <PDBx:label_comp_id>CYS</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>265</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2024">
         <PDBx:B_iso_or_equiv>12.76</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.771</PDBx:Cartn_x>
         <PDBx:Cartn_y>0.237</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.380</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>N</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>266</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>N</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2025">
         <PDBx:B_iso_or_equiv>12.68</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>16.440</PDBx:Cartn_x>
         <PDBx:Cartn_y>0.610</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.131</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CA</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>266</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2026">
         <PDBx:B_iso_or_equiv>12.80</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>17.434</PDBx:Cartn_x>
         <PDBx:Cartn_y>1.716</PDBx:Cartn_y>
         <PDBx:Cartn_z>10.369</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>C</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>266</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>C</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2027">
         <PDBx:B_iso_or_equiv>15.11</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>17.223</PDBx:Cartn_x>
         <PDBx:Cartn_y>2.489</PDBx:Cartn_y>
         <PDBx:Cartn_z>11.337</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>266</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>O</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2028">
         <PDBx:B_iso_or_equiv>13.36</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>15.454</PDBx:Cartn_x>
         <PDBx:Cartn_y>0.984</PDBx:Cartn_y>
         <PDBx:Cartn_z>9.034</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>266</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CB</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2029">
         <PDBx:B_iso_or_equiv>13.41</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>14.566</PDBx:Cartn_x>
         <PDBx:Cartn_y>-0.125</PDBx:Cartn_y>
         <PDBx:Cartn_z>8.551</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>266</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2030">
         <PDBx:B_iso_or_equiv>14.52</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>13.693</PDBx:Cartn_x>
         <PDBx:Cartn_y>0.190</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.407</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>266</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2031">
         <PDBx:B_iso_or_equiv>14.76</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>12.751</PDBx:Cartn_x>
         <PDBx:Cartn_y>1.246</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.645</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>266</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2032">
         <PDBx:B_iso_or_equiv>15.30</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.644</PDBx:Cartn_x>
         <PDBx:Cartn_y>1.633</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.032</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>266</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2033">
         <PDBx:B_iso_or_equiv>16.15</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.072</PDBx:Cartn_x>
         <PDBx:Cartn_y>1.022</PDBx:Cartn_y>
         <PDBx:Cartn_z>5.991</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>266</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_entity_id>1</PDBx:label_entity_id>
         <PDBx:label_seq_id>266</PDBx:label_seq_id>
         <PDBx:occupancy>1.00</PDBx:occupancy>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site>
      <PDBx:atom_site id="2034">
         <PDBx:B_iso_or_equiv>14.23</PDBx:B_iso_or_equiv>
         <PDBx:Cartn_x>11.368</PDBx:Cartn_x>
         <PDBx:Cartn_y>2.966</PDBx:Cartn_y>
         <PDBx:Cartn_z>7.150</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:label_entity_id>4</PDBx:label_entity_id>
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      <PDBx:atom_site id="2842">
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         <PDBx:Cartn_y>13.716</PDBx:Cartn_y>
         <PDBx:Cartn_z>-16.842</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>576</PDBx:auth_seq_id>
         <PDBx:group_PDB>HETATM</PDBx:group_PDB>
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      <PDBx:atom_site id="2843">
         <PDBx:B_iso_or_equiv>35.66</PDBx:B_iso_or_equiv>
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         <PDBx:Cartn_y>12.999</PDBx:Cartn_y>
         <PDBx:Cartn_z>-17.487</PDBx:Cartn_z>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>577</PDBx:auth_seq_id>
         <PDBx:group_PDB>HETATM</PDBx:group_PDB>
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         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
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      <PDBx:atom_sites entry_id="1LDM">
         <PDBx:fract_transf_matrix11>0.007435</PDBx:fract_transf_matrix11>
         <PDBx:fract_transf_matrix12>0.010515</PDBx:fract_transf_matrix12>
         <PDBx:fract_transf_matrix13>0.010515</PDBx:fract_transf_matrix13>
         <PDBx:fract_transf_matrix21>0.007435</PDBx:fract_transf_matrix21>
         <PDBx:fract_transf_matrix22>0.000000</PDBx:fract_transf_matrix22>
         <PDBx:fract_transf_matrix23>0.010515</PDBx:fract_transf_matrix23>
         <PDBx:fract_transf_matrix31>-0.011641</PDBx:fract_transf_matrix31>
         <PDBx:fract_transf_matrix32>0.000000</PDBx:fract_transf_matrix32>
         <PDBx:fract_transf_matrix33>0.000000</PDBx:fract_transf_matrix33>
         <PDBx:fract_transf_vector1>0.00000</PDBx:fract_transf_vector1>
         <PDBx:fract_transf_vector2>0.00000</PDBx:fract_transf_vector2>
         <PDBx:fract_transf_vector3>0.00000</PDBx:fract_transf_vector3>
      </PDBx:atom_sites>
   </PDBx:atom_sitesCategory>
   <PDBx:atom_sites_footnoteCategory>
      <PDBx:atom_sites_footnote id="1">
         <PDBx:text>RESIDUE PRO 139 IS A CIS PROLINE.</PDBx:text>
      </PDBx:atom_sites_footnote>
   </PDBx:atom_sites_footnoteCategory>
   <PDBx:atom_typeCategory>
      <PDBx:atom_type symbol="C"></PDBx:atom_type>
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      <PDBx:atom_type symbol="P"></PDBx:atom_type>
      <PDBx:atom_type symbol="S"></PDBx:atom_type>
   </PDBx:atom_typeCategory>
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      <PDBx:audit_author pdbx_ordinal="1">
         <PDBx:name>Griffith, J.P.</PDBx:name>
      </PDBx:audit_author>
      <PDBx:audit_author pdbx_ordinal="2">
         <PDBx:name>Rossmann, M.G.</PDBx:name>
      </PDBx:audit_author>
   </PDBx:audit_authorCategory>
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      <PDBx:audit_conform dict_name="mmcif_pdbx.dic" dict_version="5.287">
         <PDBx:dict_location>http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic</PDBx:dict_location>
      </PDBx:audit_conform>
   </PDBx:audit_conformCategory>
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      <PDBx:cell entry_id="1LDM">
         <PDBx:Z_PDB>16</PDBx:Z_PDB>
         <PDBx:angle_alpha>90.00</PDBx:angle_alpha>
         <PDBx:angle_beta>90.00</PDBx:angle_beta>
         <PDBx:angle_gamma>90.00</PDBx:angle_gamma>
         <PDBx:length_a>134.500</PDBx:length_a>
         <PDBx:length_b>134.500</PDBx:length_b>
         <PDBx:length_c>85.900</PDBx:length_c>
      </PDBx:cell>
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         <PDBx:formula>C3 H7 N O2</PDBx:formula>
         <PDBx:formula_weight>89.093</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ALANINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ARG">
         <PDBx:formula>C6 H15 N4 O2 1</PDBx:formula>
         <PDBx:formula_weight>175.209</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ARGININE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ASN">
         <PDBx:formula>C4 H8 N2 O3</PDBx:formula>
         <PDBx:formula_weight>132.118</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ASPARAGINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ASP">
         <PDBx:formula>C4 H7 N O4</PDBx:formula>
         <PDBx:formula_weight>133.103</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ASPARTIC ACID</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="CYS">
         <PDBx:formula>C3 H7 N O2 S</PDBx:formula>
         <PDBx:formula_weight>121.158</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>CYSTEINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLN">
         <PDBx:formula>C5 H10 N2 O3</PDBx:formula>
         <PDBx:formula_weight>146.144</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLUTAMINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLU">
         <PDBx:formula>C5 H9 N O4</PDBx:formula>
         <PDBx:formula_weight>147.129</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLUTAMIC ACID</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="GLY">
         <PDBx:formula>C2 H5 N O2</PDBx:formula>
         <PDBx:formula_weight>75.067</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>GLYCINE</PDBx:name>
         <PDBx:type>peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="HIS">
         <PDBx:formula>C6 H10 N3 O2 1</PDBx:formula>
         <PDBx:formula_weight>156.162</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>HISTIDINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="HOH">
         <PDBx:formula>H2 O</PDBx:formula>
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>WATER</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="ILE">
         <PDBx:formula>C6 H13 N O2</PDBx:formula>
         <PDBx:formula_weight>131.173</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>ISOLEUCINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="LEU">
         <PDBx:formula>C6 H13 N O2</PDBx:formula>
         <PDBx:formula_weight>131.173</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>LEUCINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="LYS">
         <PDBx:formula>C6 H15 N2 O2 1</PDBx:formula>
         <PDBx:formula_weight>147.195</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>LYSINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="MET">
         <PDBx:formula>C5 H11 N O2 S</PDBx:formula>
         <PDBx:formula_weight>149.211</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>METHIONINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="NAD">
         <PDBx:formula>C21 H27 N7 O14 P2</PDBx:formula>
         <PDBx:formula_weight>663.425</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>NICOTINAMIDE-ADENINE-DINUCLEOTIDE</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="OXM">
         <PDBx:formula>C2 H3 N O3</PDBx:formula>
         <PDBx:formula_weight>89.050</PDBx:formula_weight>
         <PDBx:mon_nstd_flag xsi:nil="true" />
         <PDBx:name>OXAMIC ACID</PDBx:name>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="PHE">
         <PDBx:formula>C9 H11 N O2</PDBx:formula>
         <PDBx:formula_weight>165.189</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>PHENYLALANINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="PRO">
         <PDBx:formula>C5 H9 N O2</PDBx:formula>
         <PDBx:formula_weight>115.130</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>PROLINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="SER">
         <PDBx:formula>C3 H7 N O3</PDBx:formula>
         <PDBx:formula_weight>105.093</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>SERINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="THR">
         <PDBx:formula>C4 H9 N O3</PDBx:formula>
         <PDBx:formula_weight>119.119</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>THREONINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="TRP">
         <PDBx:formula>C11 H12 N2 O2</PDBx:formula>
         <PDBx:formula_weight>204.225</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>TRYPTOPHAN</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="TYR">
         <PDBx:formula>C9 H11 N O3</PDBx:formula>
         <PDBx:formula_weight>181.189</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>TYROSINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
      <PDBx:chem_comp id="VAL">
         <PDBx:formula>C5 H11 N O2</PDBx:formula>
         <PDBx:formula_weight>117.146</PDBx:formula_weight>
         <PDBx:mon_nstd_flag>y</PDBx:mon_nstd_flag>
         <PDBx:name>VALINE</PDBx:name>
         <PDBx:type>L-peptide linking</PDBx:type>
      </PDBx:chem_comp>
   </PDBx:chem_compCategory>
   <PDBx:citationCategory>
      <PDBx:citation id="primary">
         <PDBx:country>UK</PDBx:country>
         <PDBx:journal_abbrev>J.Mol.Biol.</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>JMOBAK</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0070</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0022-2836</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>198</PDBx:journal_volume>
         <PDBx:page_first>445</PDBx:page_first>
         <PDBx:page_last>467</PDBx:page_last>
         <PDBx:pdbx_database_id_DOI>10.1016/0022-2836(87)90293-2</PDBx:pdbx_database_id_DOI>
         <PDBx:pdbx_database_id_PubMed>3430615</PDBx:pdbx_database_id_PubMed>
         <PDBx:title>Refined crystal structure of dogfish M4 apo-lactate dehydrogenase.</PDBx:title>
         <PDBx:year>1987</PDBx:year>
      </PDBx:citation>
      <PDBx:citation id="1">
         <PDBx:country>UK</PDBx:country>
         <PDBx:journal_abbrev>J.Mol.Biol.</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>JMOBAK</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0070</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0022-2836</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>102</PDBx:journal_volume>
         <PDBx:page_first>759</PDBx:page_first>
         <PDBx:title>A Comparison of the Structures of Apo Dogfish M4 Lactate Dehydrogenase and its Ternary Complexes</PDBx:title>
         <PDBx:year>1976</PDBx:year>
      </PDBx:citation>
      <PDBx:citation id="2">
         <PDBx:country>US</PDBx:country>
         <PDBx:journal_abbrev>Proc.Natl.Acad.Sci.USA</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>PNASA6</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0040</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0027-8424</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>74</PDBx:journal_volume>
         <PDBx:page_first>2677</PDBx:page_first>
         <PDBx:title>Structural Adaptations of Lactate Dehydrogenase Isozymes</PDBx:title>
         <PDBx:year>1977</PDBx:year>
      </PDBx:citation>
      <PDBx:citation id="3">
         <PDBx:country>UK</PDBx:country>
         <PDBx:journal_abbrev>J.Mol.Biol.</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>JMOBAK</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0070</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0022-2836</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>98</PDBx:journal_volume>
         <PDBx:page_first>259</PDBx:page_first>
         <PDBx:title>A 5 Angstroms X-Ray Diffraction Study of Coenzyme-Deficient Lactate Dehydrogenase,Nad-Pyruvate Ternary Complex</PDBx:title>
         <PDBx:year>1975</PDBx:year>
      </PDBx:citation>
      <PDBx:citation id="4">
         <PDBx:book_publisher>Academic Press,New York</PDBx:book_publisher>
         <PDBx:journal_abbrev>Isozymes-Molecular Structure</PDBx:journal_abbrev>
         <PDBx:journal_id_CSD>0979</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0-12-472701-8</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>1</PDBx:journal_volume>
         <PDBx:page_first>137</PDBx:page_first>
         <PDBx:title>A Structural Comparison of Porcine B4 and Dogfish A4 Isozymes of Lactate Dehydrogenase</PDBx:title>
         <PDBx:year>1975</PDBx:year>
      </PDBx:citation>
      <PDBx:citation id="5">
         <PDBx:book_publisher>Academic Press,New York</PDBx:book_publisher>
         <PDBx:journal_abbrev>The Enzymes,Third Edition</PDBx:journal_abbrev>
         <PDBx:journal_id_CSD>0436</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0-12-122711-1</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>11</PDBx:journal_volume>
         <PDBx:page_first>191</PDBx:page_first>
         <PDBx:title>Lactate Dehydrogenase</PDBx:title>
         <PDBx:year>1975</PDBx:year>
      </PDBx:citation>
      <PDBx:citation id="6">
         <PDBx:country>US</PDBx:country>
         <PDBx:journal_abbrev>Annu.Rev.Biochem.</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>ARBOAW</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0413</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0066-4154</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>43</PDBx:journal_volume>
         <PDBx:page_first>475</PDBx:page_first>
         <PDBx:title>X-Ray Studies of Protein Interactions</PDBx:title>
         <PDBx:year>1974</PDBx:year>
      </PDBx:citation>
      <PDBx:citation id="7">
         <PDBx:country>UK</PDBx:country>
         <PDBx:journal_abbrev>Nature</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>NATUAS</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0006</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0028-0836</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>250</PDBx:journal_volume>
         <PDBx:page_first>194</PDBx:page_first>
         <PDBx:title>Chemical and Biological Evolution of a Nucleotide Binding Protein</PDBx:title>
         <PDBx:year>1974</PDBx:year>
      </PDBx:citation>
      <PDBx:citation id="8">
         <PDBx:country>UK</PDBx:country>
         <PDBx:journal_abbrev>J.Mol.Biol.</PDBx:journal_abbrev>
         <PDBx:journal_id_ASTM>JMOBAK</PDBx:journal_id_ASTM>
         <PDBx:journal_id_CSD>0070</PDBx:journal_id_CSD>
         <PDBx:journal_id_ISSN>0022-2836</PDBx:journal_id_ISSN>
         <PDBx:journal_volume>85</PDBx:journal_volume>
         <PDBx:page_first>177</PDBx:page_first>
         <PDBx:title>Recognition of Structural Domains in Globular Proteins</PDBx:title>
         <PDBx:year>1974</PDBx:year>
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         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="4">
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:pdbx_description>water</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>245</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>nat</PDBx:src_method>
         <PDBx:type>water</PDBx:type>
      </PDBx:entity>
   </PDBx:entityCategory>
   <PDBx:entity_polyCategory>
      <PDBx:entity_poly entity_id="1">
         <PDBx:nstd_linkage>no</PDBx:nstd_linkage>
         <PDBx:nstd_monomer>no</PDBx:nstd_monomer>
         <PDBx:pdbx_seq_one_letter_code>ATLKDKLIGHLATSQEPRSYNKITVVGVGAVGMACAISILMKDLADEVALVDVMEDKLKGEMMDLQHGSLFLHTAKIVSG
KDYSVSAGSKLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKHSPDCIILVVSNPVDVLTYVAWKLSGLPMHRIIG
SGCNLDSARFRYLMGERLGVHSCSCHGWVIGEHGDSVPSVWSGMNVASIKLHPLDGTNKDKQDWKKLHKDVVDSAYEVIK
LKGYTSWAIGLSVADLAETIMKNLCRVHPVSTMVKDFYGIKDNVFLSLPCVLNDHGISNIVKMKLKPNEEQQLQKSATTL
WDIQKDLKF</PDBx:pdbx_seq_one_letter_code>
         <PDBx:pdbx_seq_one_letter_code_can>ATLKDKLIGHLATSQEPRSYNKITVVGVGAVGMACAISILMKDLADEVALVDVMEDKLKGEMMDLQHGSLFLHTAKIVSG
KDYSVSAGSKLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKHSPDCIILVVSNPVDVLTYVAWKLSGLPMHRIIG
SGCNLDSARFRYLMGERLGVHSCSCHGWVIGEHGDSVPSVWSGMNVASIKLHPLDGTNKDKQDWKKLHKDVVDSAYEVIK
LKGYTSWAIGLSVADLAETIMKNLCRVHPVSTMVKDFYGIKDNVFLSLPCVLNDHGISNIVKMKLKPNEEQQLQKSATTL
WDIQKDLKF</PDBx:pdbx_seq_one_letter_code_can>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:type>polypeptide(L)</PDBx:type>
      </PDBx:entity_poly>
   </PDBx:entity_polyCategory>
   <PDBx:entity_poly_seqCategory>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="1">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="2">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="3">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="4">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="5">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="6">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="7">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="8">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="9">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="10">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="11">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="12">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="13">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="14">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="15">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="16">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="17">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="18">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="19">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="20">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="21">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="22">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="23">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="24">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="25">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="26">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="27">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="28">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="29">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="30">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="31">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="32">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="33">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="34">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="35">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="36">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="37">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="38">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="39">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="40">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="41">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="42">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="43">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="44">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="45">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="46">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="47">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="48">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="49">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="50">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="51">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="52">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="53">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="54">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="55">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="56">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="57">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="58">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="59">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="60">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="61">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="62">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="63">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="64">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="65">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="66">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="67">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="68">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="69">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="70">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="71">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="72">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="73">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="74">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="75">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="76">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="77">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="78">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="79">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="80">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="81">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="82">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="83">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="84">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="85">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="86">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="87">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="88">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="89">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="90">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="91">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="92">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="93">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="94">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="95">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="96">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="97">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="98">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="99">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="100">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="101">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="102">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="103">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="104">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="105">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="106">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="107">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="108">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="109">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="110">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="111">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="112">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="113">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="114">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="115">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="116">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="117">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="118">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="119">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="120">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="121">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="122">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="123">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="124">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="125">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="126">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="127">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="128">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="129">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="130">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="131">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="132">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="133">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="134">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="135">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="136">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="137">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="138">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="139">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="140">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="141">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="142">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="143">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="144">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="145">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="146">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="147">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="148">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="149">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="150">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="151">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="152">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="153">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="154">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="155">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="156">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="157">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="158">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="159">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="160">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="161">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="162">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="163">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="164">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="165">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="166">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="167">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="168">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="169">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="170">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="171">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="172">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="173">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="174">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="175">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="176">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="177">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="178">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="179">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="180">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="181">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="182">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="183">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="184">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="185">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="186">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="187">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="188">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="189">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="190">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="191">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="192">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="193">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="194">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="195">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="196">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="197">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="198">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="199">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="200">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="201">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="202">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="203">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="204">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="205">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="206">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="207">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="208">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="209">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="210">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="211">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="212">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="213">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="214">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="215">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="216">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="217">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="218">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="219">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="220">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="221">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="222">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="223">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="224">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="225">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="226">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="227">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="228">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="229">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="230">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="231">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="232">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="233">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="234">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="235">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="236">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="237">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="238">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="239">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="240">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="241">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="242">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="243">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="244">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="245">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="246">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="247">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="248">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="249">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="250">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="251">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="252">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="253">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="254">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="255">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="256">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="257">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="258">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="259">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="260">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="261">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="262">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="263">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="264">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="265">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="266">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="267">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="268">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="269">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="270">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="271">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="272">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="273">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="274">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="275">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="276">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="277">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="278">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="279">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="280">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="281">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="282">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="283">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="284">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="285">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="286">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="287">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="288">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="289">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="290">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="291">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="292">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="293">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="294">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="295">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="296">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="297">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="298">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="299">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="300">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="301">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="302">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="303">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="304">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="305">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="306">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="307">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="308">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="309">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="310">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="311">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="312">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="313">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="314">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="315">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="316">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="317">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="318">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="319">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="320">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="321">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="322">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="323">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="324">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="325">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="326">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="327">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="328">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="329">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
   </PDBx:entity_poly_seqCategory>
   <PDBx:entity_src_genCategory>
      <PDBx:entity_src_gen entity_id="1" pdbx_src_id="1">
         <PDBx:gene_src_common_name>spiny dogfish</PDBx:gene_src_common_name>
         <PDBx:pdbx_alt_source_flag>sample</PDBx:pdbx_alt_source_flag>
         <PDBx:pdbx_gene_src_ncbi_taxonomy_id>7797</PDBx:pdbx_gene_src_ncbi_taxonomy_id>
         <PDBx:pdbx_gene_src_scientific_name>Squalus acanthias</PDBx:pdbx_gene_src_scientific_name>
      </PDBx:entity_src_gen>
   </PDBx:entity_src_genCategory>
   <PDBx:entryCategory>
      <PDBx:entry id="1LDM"></PDBx:entry>
   </PDBx:entryCategory>
   <PDBx:exptlCategory>
      <PDBx:exptl entry_id="1LDM" method="X-RAY DIFFRACTION">
      </PDBx:exptl>
   </PDBx:exptlCategory>
   <PDBx:exptl_crystalCategory>
      <PDBx:exptl_crystal id="1">
         <PDBx:density_Matthews>2.67</PDBx:density_Matthews>
         <PDBx:density_percent_sol>53.98</PDBx:density_percent_sol>
      </PDBx:exptl_crystal>
   </PDBx:exptl_crystalCategory>
   <PDBx:pdbx_audit_revision_categoryCategory>
      <PDBx:pdbx_audit_revision_category data_content_type="Structure model" ordinal="1" revision_ordinal="6">
         <PDBx:category>pdbx_database_status</PDBx:category>
      </PDBx:pdbx_audit_revision_category>
      <PDBx:pdbx_audit_revision_category data_content_type="Structure model" ordinal="2" revision_ordinal="6">
         <PDBx:category>struct_conf</PDBx:category>
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      <PDBx:pdbx_audit_revision_category data_content_type="Structure model" ordinal="3" revision_ordinal="6">
         <PDBx:category>struct_conf_type</PDBx:category>
      </PDBx:pdbx_audit_revision_category>
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   <PDBx:pdbx_audit_revision_detailsCategory>
      <PDBx:pdbx_audit_revision_details data_content_type="Structure model" ordinal="1" revision_ordinal="1">
         <PDBx:provider>repository</PDBx:provider>
         <PDBx:type>Initial release</PDBx:type>
      </PDBx:pdbx_audit_revision_details>
   </PDBx:pdbx_audit_revision_detailsCategory>
   <PDBx:pdbx_audit_revision_groupCategory>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="1" revision_ordinal="2">
         <PDBx:group>Version format compliance</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="2" revision_ordinal="3">
         <PDBx:group>Version format compliance</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="3" revision_ordinal="4">
         <PDBx:group>Derived calculations</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="4" revision_ordinal="4">
         <PDBx:group>Other</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
      <PDBx:pdbx_audit_revision_group data_content_type="Structure model" ordinal="5" revision_ordinal="5">
         <PDBx:group>Derived calculations</PDBx:group>
      </PDBx:pdbx_audit_revision_group>
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         <PDBx:group>Structure summary</PDBx:group>
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         <PDBx:group>Derived calculations</PDBx:group>
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         <PDBx:group>Other</PDBx:group>
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      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="1">
         <PDBx:major_revision>1</PDBx:major_revision>
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      </PDBx:pdbx_audit_revision_history>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="2">
         <PDBx:major_revision>1</PDBx:major_revision>
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         <PDBx:major_revision>1</PDBx:major_revision>
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         <PDBx:revision_date>2011-07-13</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="4">
         <PDBx:major_revision>1</PDBx:major_revision>
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         <PDBx:revision_date>2013-05-08</PDBx:revision_date>
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      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="5">
         <PDBx:major_revision>1</PDBx:major_revision>
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         <PDBx:revision_date>2014-10-22</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="6">
         <PDBx:major_revision>1</PDBx:major_revision>
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         <PDBx:revision_date>2017-11-29</PDBx:revision_date>
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      <PDBx:pdbx_audit_revision_item data_content_type="Structure model" ordinal="1" revision_ordinal="6">
         <PDBx:item>_pdbx_database_status.process_site</PDBx:item>
      </PDBx:pdbx_audit_revision_item>
   </PDBx:pdbx_audit_revision_itemCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="1LDM">
         <PDBx:SG_entry xsi:nil="true" />
         <PDBx:pdb_format_compatible>Y</PDBx:pdb_format_compatible>
         <PDBx:process_site>BNL</PDBx:process_site>
         <PDBx:recvd_initial_deposition_date>1987-11-25</PDBx:recvd_initial_deposition_date>
         <PDBx:status_code>REL</PDBx:status_code>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_entity_nonpolyCategory>
      <PDBx:pdbx_entity_nonpoly entity_id="2">
         <PDBx:comp_id>NAD</PDBx:comp_id>
         <PDBx:name>NICOTINAMIDE-ADENINE-DINUCLEOTIDE</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="3">
         <PDBx:comp_id>OXM</PDBx:comp_id>
         <PDBx:name>OXAMIC ACID</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="4">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_entry_detailsCategory>
      <PDBx:pdbx_entry_details entry_id="1LDM">
         <PDBx:sequence_details>THE RESIDUES IN THIS ENTRY ARE NUMBERED SEQUENTIALLY FROM
1 - 329.  SEE THE PAPER CITED AS REFERENCE 1 ABOVE FOR AN
EXPLANATION OF THE NUMBERING SYSTEM USED IN SOME EARLIER
LDH ENTRIES.</PDBx:sequence_details>
      </PDBx:pdbx_entry_details>
   </PDBx:pdbx_entry_detailsCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="B" ndb_seq_num="1">
         <PDBx:auth_mon_id>NAD</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:mon_id>NAD</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>NAD</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>330</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="C" ndb_seq_num="1">
         <PDBx:auth_mon_id>OXM</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>OXM</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>OXM</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>331</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="D" ndb_seq_num="1">
         <PDBx:auth_mon_id>OXM</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>OXM</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>OXM</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>332</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>331</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>333</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>332</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>334</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>333</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>335</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="4">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>334</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>336</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="5">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>335</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>337</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="6">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>336</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>338</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="7">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>337</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>339</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="8">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>338</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>340</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="9">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>339</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>341</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="10">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>340</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>342</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="11">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>341</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>343</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="12">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>342</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>344</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="13">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>343</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>345</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="14">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>344</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>346</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="15">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>345</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>347</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="16">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>346</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>348</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="17">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>347</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>349</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="18">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>348</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>350</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="19">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>349</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>351</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="20">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>350</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>352</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="21">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>351</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>353</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="22">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>352</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>354</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="23">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>353</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>355</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="24">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>354</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>356</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="25">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>355</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>357</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="26">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>356</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>358</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="27">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>357</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>359</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="28">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>358</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>360</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="29">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>359</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>361</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="30">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>360</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>362</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="31">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>361</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>363</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="32">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>362</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>364</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="33">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>363</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>365</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="34">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>364</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>366</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="35">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>365</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>367</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="36">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>366</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>368</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="37">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>367</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>369</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="38">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>368</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>370</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="39">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>369</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>371</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="40">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>370</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>372</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="41">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>371</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>373</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="42">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>372</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>374</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="43">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>373</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>375</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="44">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>374</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>376</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="45">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>375</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>377</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="46">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>376</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>378</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="47">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>377</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>379</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="48">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>378</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>380</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="49">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>379</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>381</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="50">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>380</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>382</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="51">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>381</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>383</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="52">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>382</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>384</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="53">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>383</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>385</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="54">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>384</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>386</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="55">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>385</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>387</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="56">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>386</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>388</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="57">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>387</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>389</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="58">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>388</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>390</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="59">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>389</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>391</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="60">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>390</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>392</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="61">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>391</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>393</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="62">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>392</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>394</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="63">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>393</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>395</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="64">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>394</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>396</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="65">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>395</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>397</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="66">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>396</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>398</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="67">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>397</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>399</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="68">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>398</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>400</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="69">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>399</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>401</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="70">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>400</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>402</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="71">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>401</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>403</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="72">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>402</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>404</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="73">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>403</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>405</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="74">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>404</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>406</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="75">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>405</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>407</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="76">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>406</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>408</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="77">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>407</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>409</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="78">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>408</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>410</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="79">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>409</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>411</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="80">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>410</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>412</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="81">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>411</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>413</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="82">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>412</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>414</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="83">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>413</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>415</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="84">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>414</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>416</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="85">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>415</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>417</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="86">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>416</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>418</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="87">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>417</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>419</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="88">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>418</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>420</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="89">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>419</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>421</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="90">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>420</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>422</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="91">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>421</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>423</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="92">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>422</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>424</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="93">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>423</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>425</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="94">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>424</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>426</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="95">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>425</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>427</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="96">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>426</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>428</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="97">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>427</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>429</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="98">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>428</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>430</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="99">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>429</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>431</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="100">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>430</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>432</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="101">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>431</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>433</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="102">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>432</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>434</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="103">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>433</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>435</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="104">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>434</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>436</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="105">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>435</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>437</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="106">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>436</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>438</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="107">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>437</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>439</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="108">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>438</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>440</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="109">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>439</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>441</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="110">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>440</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>442</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="111">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>441</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>443</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="112">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>442</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>444</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="113">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>443</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>445</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="114">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>444</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>446</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="115">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>445</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>447</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="116">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>446</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>448</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="117">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>447</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>449</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="118">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>449</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>450</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="119">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>450</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>451</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="120">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>451</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>452</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="121">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>452</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>453</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="122">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>453</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>454</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="123">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>454</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>455</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="124">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>455</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>456</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="125">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>456</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>457</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="126">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>457</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>458</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="127">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>458</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>459</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="128">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>459</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>460</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="129">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>460</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>461</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="130">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>461</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>462</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="131">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>462</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>463</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="132">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>463</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>464</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="133">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>464</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>465</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="134">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>465</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>466</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="135">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>466</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>467</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="136">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>467</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>468</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="137">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>468</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>469</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="138">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>469</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>470</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="139">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>470</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>471</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="140">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>471</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>472</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="141">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>472</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>473</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="142">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>473</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>474</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="143">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>474</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>475</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="144">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>475</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>476</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="145">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>476</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>477</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="146">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>477</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>478</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="147">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>478</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>479</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="148">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>479</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>480</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="149">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>480</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>481</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="150">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>481</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>482</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="151">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>482</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>483</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="152">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>483</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>484</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="153">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>484</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>485</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="154">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>485</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>486</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="155">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>486</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>487</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="156">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>487</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>488</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="157">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>488</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>489</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="158">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>489</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>490</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="159">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>490</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>491</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="160">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>491</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>492</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="161">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>492</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>493</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="162">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>493</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>494</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="163">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>494</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>495</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="164">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>495</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>496</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="165">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>496</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>497</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="166">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>497</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>498</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="167">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>498</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>499</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="168">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>499</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>500</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="169">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>501</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>501</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="170">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>502</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>502</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="171">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>503</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>503</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="172">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>504</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>504</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="173">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>505</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>505</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="174">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>506</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>506</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="175">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>507</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>507</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="176">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>508</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>508</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="177">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>509</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>509</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="178">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>510</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>510</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="179">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>511</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>511</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="180">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>512</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>512</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="181">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>513</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>513</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="182">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>514</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>514</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="183">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>515</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>515</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="184">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>516</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>516</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="185">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>517</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>517</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="186">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>518</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>518</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="187">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>519</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>519</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="188">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>520</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>520</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="189">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>521</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>521</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="190">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>522</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>522</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="191">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>523</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>523</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="192">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>524</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>524</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="193">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>525</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>525</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="194">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>526</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>526</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="195">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>527</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>527</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="196">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>528</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>528</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="197">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>529</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>529</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="198">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>530</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>530</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="199">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>531</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>531</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="200">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>532</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>532</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="201">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>533</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>533</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="202">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>534</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>534</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="203">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>535</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>535</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="204">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>536</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>536</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="205">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>537</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>537</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="206">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>538</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>538</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="207">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>539</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>539</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="208">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>540</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>540</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="209">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>541</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>541</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="210">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>542</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>542</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="211">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>543</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>543</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="212">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>544</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>544</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="213">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>545</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>545</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="214">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>546</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>546</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="215">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>547</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>547</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="216">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>548</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>548</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="217">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>549</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>549</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="218">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>550</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>550</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="219">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>551</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>551</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="220">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>552</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>552</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="221">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>553</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>553</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="222">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>554</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>554</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="223">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>555</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>555</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="224">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>556</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>556</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="225">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>557</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>557</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="226">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>558</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>558</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="227">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>559</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>559</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="228">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>560</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>560</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="229">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>561</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>561</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="230">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>562</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>562</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="231">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>563</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>563</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="232">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>564</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>564</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="233">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>565</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>565</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="234">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>566</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>566</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="235">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>567</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>567</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="236">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>568</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>568</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="237">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>569</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>569</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="238">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>570</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>570</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="239">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>571</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>571</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="240">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>572</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>572</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="241">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>573</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>573</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="242">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>574</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>574</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="243">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>575</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>575</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="244">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>576</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>576</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="245">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>577</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>577</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_point_symmetryCategory>
      <PDBx:pdbx_point_symmetry entry_id="1LDM">
         <PDBx:Schoenflies_symbol>D</PDBx:Schoenflies_symbol>
         <PDBx:circular_symmetry>2</PDBx:circular_symmetry>
      </PDBx:pdbx_point_symmetry>
   </PDBx:pdbx_point_symmetryCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="1">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>1</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="2">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>2</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="3">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>3</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="4">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>4</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="5">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>5</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="6">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>6</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="7">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>7</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>7</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="8">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>8</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>8</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="9">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>9</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>9</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="10">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>10</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>10</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="11">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>11</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>11</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="12">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>12</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>12</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="13">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>13</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>13</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="14">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>14</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>14</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>14</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="15">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>15</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>15</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>15</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="16">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>16</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>16</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>16</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="17">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>17</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>17</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>17</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="18">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>18</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>18</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>18</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="19">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>19</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>19</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>19</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="20">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>20</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>20</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>20</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="21">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>21</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>21</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>21</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="22">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>22</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>22</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>22</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="23">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>23</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>23</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>23</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="24">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>24</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>24</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>24</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="25">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>25</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>25</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>25</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="26">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>26</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>26</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>26</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="27">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>27</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>27</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>27</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="28">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>28</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>28</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>28</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="29">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>29</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>29</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>29</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="30">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>30</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>30</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>30</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="31">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>31</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>31</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>31</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="32">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>32</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>32</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>32</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="33">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>33</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>33</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>33</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="34">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>34</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>34</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>34</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="35">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>35</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>35</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>35</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="36">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>36</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>36</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>36</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="37">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>37</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>37</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>37</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="38">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>38</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>38</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>38</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="39">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>39</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>39</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>39</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="40">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>40</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>40</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>40</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="41">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>41</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>41</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>41</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="42">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>42</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>42</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>42</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="43">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>43</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>43</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>43</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="44">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>44</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>44</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>44</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="45">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>45</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>45</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>45</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="46">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>46</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>46</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>46</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="47">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>47</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>47</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>47</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="48">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>48</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>48</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>48</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="49">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>49</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>49</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>49</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="50">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>50</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>50</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>50</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="51">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>51</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>51</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>51</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="52">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>52</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>52</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>52</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="53">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>53</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>53</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>53</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="54">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>54</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>54</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>54</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="55">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>55</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>55</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>55</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="56">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>56</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>56</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>56</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="57">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>57</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>57</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>57</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="58">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>58</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>58</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>58</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="59">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>59</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>59</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>59</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="60">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>60</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>60</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>60</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="61">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>61</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>61</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>61</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="62">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>62</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>62</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>62</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="63">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>63</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>63</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>63</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="64">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>64</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>64</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>64</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="65">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>65</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>65</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>65</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="66">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>66</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>66</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>66</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="67">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>67</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>67</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>67</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="68">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>68</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>68</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>68</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="69">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>69</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>69</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>69</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="70">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>70</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>70</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>70</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="71">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>71</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>71</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>71</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="72">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>72</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>72</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>72</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="73">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>73</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>73</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>73</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="74">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>74</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>74</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>74</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="75">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>75</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>75</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>75</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="76">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>76</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>76</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>76</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="77">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>77</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>77</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>77</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="78">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>78</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>78</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>78</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="79">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>79</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>79</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>79</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="80">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>80</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>80</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>80</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="81">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>81</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>81</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>81</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="82">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>82</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>82</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>82</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="83">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>83</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>83</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>83</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="84">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>84</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>84</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>84</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="85">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>85</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>85</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>85</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="86">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>86</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>86</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>86</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="87">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>87</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>87</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>87</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="88">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>88</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>88</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>88</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="89">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>89</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>89</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>89</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="90">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>90</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>90</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>90</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="91">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>91</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>91</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>91</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="92">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>92</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>92</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>92</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="93">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>93</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>93</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>93</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="94">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>94</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>94</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>94</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="95">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>95</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>95</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>95</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="96">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>96</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>96</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>96</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="97">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>97</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>97</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>97</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="98">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>98</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>98</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>98</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="99">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>99</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>99</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>99</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="100">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>100</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>100</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>100</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="101">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>101</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>101</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>101</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="102">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>102</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>102</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>102</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="103">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>103</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>103</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>103</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="104">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>104</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>104</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>104</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="105">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>105</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>105</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>105</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="106">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>106</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>106</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>106</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="107">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>107</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>107</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>107</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="108">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>108</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>108</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>108</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="109">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>109</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>109</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>109</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="110">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>110</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>110</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>110</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="111">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>111</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>111</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>111</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="112">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>112</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>112</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>112</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="113">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>113</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>113</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>113</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="114">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>114</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>114</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>114</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="115">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>115</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>115</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>115</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="116">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>116</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>116</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>116</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="117">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>117</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>117</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>117</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="118">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>118</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>118</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>118</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="119">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>119</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>119</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>119</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="120">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>120</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>120</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>120</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="121">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>121</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>121</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>121</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="122">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>122</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>122</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>122</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="123">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>123</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>123</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>123</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="124">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>124</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>124</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>124</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="125">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>125</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>125</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>125</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="126">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>126</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>126</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>126</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="127">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>127</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>127</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>127</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="128">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>128</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>128</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>128</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="129">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>129</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>129</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>129</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="130">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>130</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>130</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>130</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="131">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>131</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>131</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>131</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="132">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>132</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>132</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>132</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="133">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>133</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>133</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>133</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="134">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>134</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>134</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>134</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="135">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>135</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>135</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>135</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="136">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>136</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>136</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>136</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="137">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>137</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>137</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>137</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="138">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>138</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>138</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>138</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="139">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>139</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>139</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>139</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="140">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>140</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>140</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>140</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="141">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>141</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>141</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>141</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="142">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>142</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>142</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>142</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="143">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>143</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>143</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>143</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="144">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>144</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>144</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>144</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="145">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>145</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>145</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>145</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="146">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>146</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>146</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>146</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="147">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>147</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>147</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>147</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="148">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>148</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>148</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>148</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="149">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>149</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>149</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>149</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="150">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>150</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>150</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>150</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="151">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>151</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>151</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>151</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="152">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>152</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>152</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>152</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="153">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>153</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>153</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>153</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="154">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>154</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>154</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>154</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="155">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>155</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>155</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>155</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="156">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>156</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>156</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>156</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="157">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>157</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>157</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>157</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="158">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>158</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>158</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>158</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="159">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>159</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>159</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>159</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="160">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>160</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>160</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>160</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="161">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>161</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>161</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>161</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="162">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>162</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>162</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>162</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="163">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>163</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>163</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>163</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="164">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>164</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>164</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>164</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="165">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>165</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>165</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>165</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="166">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>166</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>166</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>166</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="167">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>167</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>167</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>167</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="168">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>168</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>168</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>168</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="169">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>169</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>169</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>169</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="170">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>170</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>170</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>170</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="171">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>171</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>171</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>171</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="172">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>172</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>172</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>172</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="173">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>173</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>173</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>173</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="174">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>174</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>174</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>174</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="175">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>175</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>175</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>175</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="176">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>176</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>176</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>176</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="177">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>177</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>177</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>177</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="178">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>178</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>178</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>178</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="179">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>179</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>179</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>179</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="180">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>180</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>180</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>180</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="181">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>181</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>181</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>181</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="182">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>182</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>182</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>182</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="183">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>183</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>183</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>183</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="184">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>184</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>184</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>184</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="185">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>185</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>185</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>185</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="186">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>186</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>186</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>186</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="187">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>187</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>187</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>187</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="188">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>188</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>188</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>188</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="189">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>189</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>189</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>189</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="190">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>190</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>190</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>190</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="191">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>191</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>191</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>191</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="192">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>192</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>192</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>192</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="193">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>193</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>193</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>193</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="194">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>194</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>194</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>194</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="195">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>195</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>195</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>195</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="196">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>196</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>196</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>196</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="197">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>197</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>197</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>197</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="198">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>198</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>198</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>198</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="199">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>199</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>199</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>199</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="200">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>200</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>200</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>200</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="201">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>201</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>201</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>201</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="202">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>202</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>202</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>202</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="203">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>203</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>203</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>203</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="204">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>204</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>204</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>204</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="205">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>205</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>205</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>205</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="206">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>206</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>206</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>206</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="207">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>207</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>207</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>207</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="208">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>208</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>208</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>208</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="209">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>209</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>209</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>209</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="210">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>210</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>210</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>210</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="211">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>211</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>211</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>211</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="212">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>212</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>212</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>212</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="213">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>213</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>213</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>213</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="214">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>214</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>214</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>214</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="215">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>215</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>215</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>215</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="216">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>216</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>216</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>216</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="217">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>217</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>217</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>217</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="218">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>218</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>218</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>218</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="219">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>219</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>219</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>219</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="220">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>220</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>220</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>220</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="221">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>221</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>221</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>221</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="222">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>222</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>222</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>222</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="223">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>223</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>223</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>223</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="224">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>224</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>224</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>224</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="225">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>225</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>225</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>225</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="226">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>226</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>226</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>226</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="227">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>227</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>227</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>227</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="228">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>228</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>228</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>228</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="229">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>229</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>229</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>229</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="230">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>230</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>230</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>230</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="231">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>231</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>231</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>231</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="232">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>232</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>232</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>232</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="233">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>233</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>233</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>233</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="234">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>234</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>234</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>234</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="235">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>235</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>235</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>235</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="236">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>236</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>236</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>236</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="237">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>237</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>237</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>237</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="238">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>238</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>238</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>238</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="239">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>239</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>239</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>239</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="240">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>240</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>240</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>240</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="241">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>241</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>241</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>241</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="242">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>242</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>242</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>242</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="243">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>243</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>243</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>243</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="244">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>244</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>244</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>244</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="245">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>245</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>245</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>245</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="246">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>246</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>246</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>246</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="247">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>247</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>247</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>247</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="248">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>248</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>248</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>248</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="249">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>249</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>249</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>249</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="250">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>250</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>250</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>250</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="251">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>251</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>251</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>251</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="252">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>252</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>252</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>252</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="253">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>253</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>253</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>253</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="254">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>254</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>254</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>254</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="255">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>255</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>255</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>255</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="256">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>256</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>256</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>256</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="257">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>257</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>257</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>257</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="258">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>258</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>258</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>258</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="259">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>259</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>259</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>259</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="260">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>260</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>260</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>260</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="261">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>261</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>261</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>261</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="262">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>262</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>262</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>262</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="263">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>263</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>263</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>263</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="264">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>264</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>264</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>264</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="265">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>265</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>265</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>265</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="266">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>266</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>266</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>266</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="267">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>267</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>267</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>267</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="268">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>268</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>268</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>268</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="269">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>269</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>269</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>269</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="270">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>270</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>270</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>270</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="271">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>271</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>271</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>271</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="272">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>272</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>272</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>272</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="273">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>273</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>273</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>273</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="274">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>274</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>274</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>274</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="275">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>275</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>275</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>275</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="276">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>276</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>276</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>276</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="277">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>277</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>277</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>277</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="278">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>278</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>278</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>278</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="279">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>279</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>279</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>279</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="280">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>280</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>280</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>280</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="281">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>281</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>281</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>281</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="282">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>282</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>282</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>282</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="283">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>283</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>283</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>283</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="284">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>284</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>284</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>284</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="285">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>285</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>285</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>285</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="286">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>286</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>286</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>286</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="287">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>287</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>287</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>287</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="288">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>288</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>288</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>288</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="289">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>289</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>289</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>289</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="290">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>290</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>290</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>290</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="291">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>291</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>291</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>291</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="292">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>292</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>292</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>292</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="293">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>293</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>293</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>293</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="294">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>294</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>294</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>294</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="295">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>295</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>295</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>295</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="296">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>296</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>296</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>296</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="297">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>297</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>297</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>297</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="298">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>298</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>298</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>298</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="299">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>299</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>299</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>299</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="300">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>300</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>300</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>300</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="301">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>301</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>301</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>301</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="302">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>302</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>302</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>302</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="303">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>303</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>303</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>303</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="304">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>304</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>304</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>304</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="305">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>305</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>305</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>305</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="306">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>306</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>306</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>306</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="307">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>307</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>307</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>307</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="308">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>308</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>308</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>308</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="309">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>309</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>309</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>309</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="310">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>310</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>310</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>310</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="311">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>311</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>311</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>311</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="312">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>312</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>312</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>312</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="313">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>313</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>313</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>313</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="314">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>314</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>314</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>314</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="315">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>315</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>315</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>315</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="316">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>316</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>316</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>316</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="317">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>317</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>317</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>317</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="318">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>318</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>318</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>318</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="319">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>319</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>319</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>319</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="320">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>320</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>320</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>320</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="321">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>321</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>321</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>321</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="322">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>322</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>322</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>322</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="323">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>323</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>323</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>323</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="324">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>324</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>324</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>324</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="325">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>325</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>325</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>325</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="326">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>326</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>326</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>326</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="327">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>327</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>327</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>327</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="328">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>328</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>328</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>328</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="329">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>329</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>329</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>329</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>complete point assembly</PDBx:details>
         <PDBx:oligomeric_count>4</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>4-MERIC</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
      <PDBx:pdbx_struct_assembly id="2">
         <PDBx:details>point asymmetric unit</PDBx:details>
         <PDBx:oligomeric_count>1</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>monomeric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
      <PDBx:pdbx_struct_assembly id="3">
         <PDBx:details>point asymmetric unit, std point frame</PDBx:details>
         <PDBx:oligomeric_count>1</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>monomeric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
      <PDBx:pdbx_struct_assembly id="4">
         <PDBx:details>crystal asymmetric unit, crystal frame</PDBx:details>
         <PDBx:oligomeric_count>1</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>monomeric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B,C,D,E" oper_expression="(1-4)"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="2" asym_id_list="A,B,C,D,E" oper_expression="1"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="3" asym_id_list="A,B,C,D,E" oper_expression="P"></PDBx:pdbx_struct_assembly_gen>
      <PDBx:pdbx_struct_assembly_gen assembly_id="4" asym_id_list="A,B,C,D,E" oper_expression="(X0)(1)"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="P">
         <PDBx:matrix11>1.00000000</PDBx:matrix11>
         <PDBx:matrix12>0.00000000</PDBx:matrix12>
         <PDBx:matrix13>0.00000000</PDBx:matrix13>
         <PDBx:matrix21>0.00000000</PDBx:matrix21>
         <PDBx:matrix22>0.00000000</PDBx:matrix22>
         <PDBx:matrix23>-1.00000000</PDBx:matrix23>
         <PDBx:matrix31>0.00000000</PDBx:matrix31>
         <PDBx:matrix32>1.00000000</PDBx:matrix32>
         <PDBx:matrix33>0.00000000</PDBx:matrix33>
         <PDBx:type>transform to point frame</PDBx:type>
         <PDBx:vector1>0.00000</PDBx:vector1>
         <PDBx:vector2>0.00000</PDBx:vector2>
         <PDBx:vector3>0.00000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="X0">
         <PDBx:matrix11>1.00000000</PDBx:matrix11>
         <PDBx:matrix12>0.00000000</PDBx:matrix12>
         <PDBx:matrix13>0.00000000</PDBx:matrix13>
         <PDBx:matrix21>0.00000000</PDBx:matrix21>
         <PDBx:matrix22>1.00000000</PDBx:matrix22>
         <PDBx:matrix23>0.00000000</PDBx:matrix23>
         <PDBx:matrix31>0.00000000</PDBx:matrix31>
         <PDBx:matrix32>0.00000000</PDBx:matrix32>
         <PDBx:matrix33>1.00000000</PDBx:matrix33>
         <PDBx:type>transform to crystal frame</PDBx:type>
         <PDBx:vector1>0.00000</PDBx:vector1>
         <PDBx:vector2>0.00000</PDBx:vector2>
         <PDBx:vector3>0.00000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.00000000</PDBx:matrix11>
         <PDBx:matrix12>0.00000000</PDBx:matrix12>
         <PDBx:matrix13>0.00000000</PDBx:matrix13>
         <PDBx:matrix21>0.00000000</PDBx:matrix21>
         <PDBx:matrix22>1.00000000</PDBx:matrix22>
         <PDBx:matrix23>0.00000000</PDBx:matrix23>
         <PDBx:matrix31>0.00000000</PDBx:matrix31>
         <PDBx:matrix32>0.00000000</PDBx:matrix32>
         <PDBx:matrix33>1.00000000</PDBx:matrix33>
         <PDBx:type>point symmetry operation</PDBx:type>
         <PDBx:vector1>0.00000</PDBx:vector1>
         <PDBx:vector2>0.00000</PDBx:vector2>
         <PDBx:vector3>0.00000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="2">
         <PDBx:matrix11>-1.00000000</PDBx:matrix11>
         <PDBx:matrix12>0.00000000</PDBx:matrix12>
         <PDBx:matrix13>0.00000000</PDBx:matrix13>
         <PDBx:matrix21>0.00000000</PDBx:matrix21>
         <PDBx:matrix22>1.00000000</PDBx:matrix22>
         <PDBx:matrix23>0.00000000</PDBx:matrix23>
         <PDBx:matrix31>0.00000000</PDBx:matrix31>
         <PDBx:matrix32>0.00000000</PDBx:matrix32>
         <PDBx:matrix33>-1.00000000</PDBx:matrix33>
         <PDBx:type>point symmetry operation</PDBx:type>
         <PDBx:vector1>0.00000</PDBx:vector1>
         <PDBx:vector2>0.00000</PDBx:vector2>
         <PDBx:vector3>0.00000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="3">
         <PDBx:matrix11>1.00000000</PDBx:matrix11>
         <PDBx:matrix12>0.00000000</PDBx:matrix12>
         <PDBx:matrix13>0.00000000</PDBx:matrix13>
         <PDBx:matrix21>0.00000000</PDBx:matrix21>
         <PDBx:matrix22>-1.00000000</PDBx:matrix22>
         <PDBx:matrix23>0.00000000</PDBx:matrix23>
         <PDBx:matrix31>0.00000000</PDBx:matrix31>
         <PDBx:matrix32>0.00000000</PDBx:matrix32>
         <PDBx:matrix33>-1.00000000</PDBx:matrix33>
         <PDBx:type>point symmetry operation</PDBx:type>
         <PDBx:vector1>0.00000</PDBx:vector1>
         <PDBx:vector2>0.00000</PDBx:vector2>
         <PDBx:vector3>0.00000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
      <PDBx:pdbx_struct_oper_list id="4">
         <PDBx:matrix11>-1.00000000</PDBx:matrix11>
         <PDBx:matrix12>0.00000000</PDBx:matrix12>
         <PDBx:matrix13>0.00000000</PDBx:matrix13>
         <PDBx:matrix21>0.00000000</PDBx:matrix21>
         <PDBx:matrix22>-1.00000000</PDBx:matrix22>
         <PDBx:matrix23>0.00000000</PDBx:matrix23>
         <PDBx:matrix31>0.00000000</PDBx:matrix31>
         <PDBx:matrix32>0.00000000</PDBx:matrix32>
         <PDBx:matrix33>1.00000000</PDBx:matrix33>
         <PDBx:type>point symmetry operation</PDBx:type>
         <PDBx:vector1>0.00000</PDBx:vector1>
         <PDBx:vector2>0.00000</PDBx:vector2>
         <PDBx:vector3>0.00000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_struct_sheet_hbondCategory>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="SH1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>VAL</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>78</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>VAL</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>78</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LEU</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>50</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LEU</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>50</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="2" range_id_2="3" sheet_id="SH1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>ALA</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>49</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>ALA</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>49</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>VAL</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>25</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>VAL</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>25</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="3" range_id_2="4" sheet_id="SH1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>THR</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>24</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>THR</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>24</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>VAL</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>93</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>VAL</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>93</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="4" range_id_2="5" sheet_id="SH1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>VAL</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>92</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>VAL</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>92</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LEU</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>134</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LEU</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>134</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="5" range_id_2="6" sheet_id="SH1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>ILE</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>133</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>ILE</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>133</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ILE</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>159</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ILE</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>159</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="SH2">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>SER</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>184</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>SER</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>184</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ASN</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>205</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ASN</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>205</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="2" range_id_2="3" sheet_id="SH2">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>VAL</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>206</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>VAL</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>206</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ILE</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>209</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ILE</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>209</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="SH3">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>VAL</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>267</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>VAL</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>267</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>CYS</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>290</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>CYS</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>290</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="2" range_id_2="3" sheet_id="SH3">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>O</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>CYS</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>290</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>O</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>CYS</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>290</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>N</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>ASN</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>299</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>N</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>ASN</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>299</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
   </PDBx:pdbx_struct_sheet_hbondCategory>
   <PDBx:pdbx_validate_close_contactCategory>
      <PDBx:pdbx_validate_close_contact id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>170</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:dist>1.63</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>9</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>163</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>164</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>198</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>199</PDBx:auth_seq_id_2>
         <PDBx:dist>1.74</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>317</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O3B</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>52</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>154</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>155</PDBx:auth_seq_id_2>
         <PDBx:dist>1.77</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>276</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:dist>1.77</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>305</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>306</PDBx:auth_seq_id_2>
         <PDBx:dist>1.78</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:dist>1.78</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N1A</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>NAD</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>330</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>373</PDBx:auth_seq_id_2>
         <PDBx:dist>1.79</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>74</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>75</PDBx:auth_seq_id_2>
         <PDBx:dist>1.79</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="13">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>241</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>242</PDBx:auth_seq_id_2>
         <PDBx:dist>1.79</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="14">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>328</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>329</PDBx:auth_seq_id_2>
         <PDBx:dist>1.80</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="15">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>450</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>452</PDBx:auth_seq_id_2>
         <PDBx:dist>1.86</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="16">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>212</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>216</PDBx:auth_seq_id_2>
         <PDBx:dist>1.87</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="17">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>258</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>262</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="18">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>102</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>357</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="19">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>147</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>151</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="20">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>347</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="21">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>152</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="22">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="23">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>113</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>117</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="24">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>319</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>451</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="25">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>210</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>561</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="26">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>465</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>466</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="27">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>444</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
   </PDBx:pdbx_validate_close_contactCategory>
   <PDBx:pdbx_validate_planesCategory>
      <PDBx:pdbx_validate_planes id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>106</PDBx:auth_seq_id>
         <PDBx:rmsd>0.117</PDBx:rmsd>
         <PDBx:type>SIDE CHAIN</PDBx:type>
      </PDBx:pdbx_validate_planes>
      <PDBx:pdbx_validate_planes id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>171</PDBx:auth_seq_id>
         <PDBx:rmsd>0.135</PDBx:rmsd>
         <PDBx:type>SIDE CHAIN</PDBx:type>
      </PDBx:pdbx_validate_planes>
      <PDBx:pdbx_validate_planes id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>266</PDBx:auth_seq_id>
         <PDBx:rmsd>0.129</PDBx:rmsd>
         <PDBx:type>SIDE CHAIN</PDBx:type>
      </PDBx:pdbx_validate_planes>
   </PDBx:pdbx_validate_planesCategory>
   <PDBx:pdbx_validate_rmsd_angleCategory>
      <PDBx:pdbx_validate_rmsd_angle id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>8.32</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>118.30</PDBx:angle_target_value>
         <PDBx:angle_value>126.62</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>OD1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>5</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>5</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>7.61</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>118.30</PDBx:angle_target_value>
         <PDBx:angle_value>125.91</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>OD1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>52</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>52</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-6.56</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>118.30</PDBx:angle_target_value>
         <PDBx:angle_value>111.74</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>OD2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>52</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>52</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>5.57</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>118.30</PDBx:angle_target_value>
         <PDBx:angle_value>123.87</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>OD1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>56</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>56</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>56</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>6.24</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>118.30</PDBx:angle_target_value>
         <PDBx:angle_value>124.54</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>OD1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>64</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>64</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>64</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.40</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>113.40</PDBx:angle_target_value>
         <PDBx:angle_value>126.80</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LYS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>81</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>81</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-3.82</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>120.30</PDBx:angle_target_value>
         <PDBx:angle_value>116.48</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>NE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NH2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ARG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>106</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>106</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>106</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.43</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>113.40</PDBx:angle_target_value>
         <PDBx:angle_value>126.83</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LYS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>118</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>118</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>5.40</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>118.30</PDBx:angle_target_value>
         <PDBx:angle_value>123.70</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>OD1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>130</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>130</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>130</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>21.16</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>113.40</PDBx:angle_target_value>
         <PDBx:angle_value>134.56</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ARG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>171</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>171</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.25</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>123.60</PDBx:angle_target_value>
         <PDBx:angle_value>136.85</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CZ</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ARG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>171</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>171</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>6.67</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>120.30</PDBx:angle_target_value>
         <PDBx:angle_value>126.97</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>NE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NH1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ARG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>171</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>171</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="13">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-10.05</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>120.30</PDBx:angle_target_value>
         <PDBx:angle_value>110.25</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>NE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NH2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ARG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>171</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>171</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="14">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>19.55</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>113.40</PDBx:angle_target_value>
         <PDBx:angle_value>132.95</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>176</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>176</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>176</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="15">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>7.11</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>118.30</PDBx:angle_target_value>
         <PDBx:angle_value>125.41</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>OD1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>195</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>195</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>195</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="16">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-17.85</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>111.50</PDBx:angle_target_value>
         <PDBx:angle_value>93.65</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>197</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>197</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="17">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.91</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.90</PDBx:angle_target_value>
         <PDBx:angle_value>124.81</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>VAL</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>197</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>197</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="18">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.23</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.20</PDBx:angle_target_value>
         <PDBx:angle_value>122.43</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>C</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LEU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>256</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>256</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>256</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="19">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>13.65</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>113.40</PDBx:angle_target_value>
         <PDBx:angle_value>127.05</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>LYS</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>262</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>262</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>262</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="20">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>9.84</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.40</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>123.60</PDBx:angle_target_value>
         <PDBx:angle_value>133.44</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CZ</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ARG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>266</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>266</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="21">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>5.54</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>120.30</PDBx:angle_target_value>
         <PDBx:angle_value>125.84</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>NE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NH1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ARG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>266</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>266</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="22">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-5.83</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.50</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>120.30</PDBx:angle_target_value>
         <PDBx:angle_value>114.47</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>NE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>NH2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ARG</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>266</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>266</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="23">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>11.08</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>118.30</PDBx:angle_target_value>
         <PDBx:angle_value>129.38</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>OD1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>294</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>294</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="24">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>-6.08</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>0.90</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>118.30</PDBx:angle_target_value>
         <PDBx:angle_value>112.22</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>OD2</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>294</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>294</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="25">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>14.86</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.20</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>113.40</PDBx:angle_target_value>
         <PDBx:angle_value>128.26</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CG</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>ASN</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>299</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>299</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>299</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="26">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.92</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>2.00</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>118.30</PDBx:angle_target_value>
         <PDBx:angle_value>131.22</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>OE1</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>GLU</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>310</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>310</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>310</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
      <PDBx:pdbx_validate_rmsd_angle id="27">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:angle_deviation>12.27</PDBx:angle_deviation>
         <PDBx:angle_standard_deviation>1.80</PDBx:angle_standard_deviation>
         <PDBx:angle_target_value>110.60</PDBx:angle_target_value>
         <PDBx:angle_value>122.87</PDBx:angle_value>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_asym_id_3>A</PDBx:auth_asym_id_3>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_atom_id_3>CB</PDBx:auth_atom_id_3>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_comp_id_3>TRP</PDBx:auth_comp_id_3>
         <PDBx:auth_seq_id_1>321</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:auth_seq_id_3>321</PDBx:auth_seq_id_3>
         <PDBx:linker_flag>N</PDBx:linker_flag>
      </PDBx:pdbx_validate_rmsd_angle>
   </PDBx:pdbx_validate_rmsd_angleCategory>
   <PDBx:pdbx_validate_symm_contactCategory>
      <PDBx:pdbx_validate_symm_contact id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>175</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>0.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>119</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>258</PDBx:auth_seq_id_2>
         <PDBx:dist>0.20</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>0.22</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>29</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:dist>0.23</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>75</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>157</PDBx:auth_seq_id_2>
         <PDBx:dist>0.35</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>56</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>0.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>245</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>537</PDBx:auth_seq_id_2>
         <PDBx:dist>0.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:dist>0.37</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>118</PDBx:auth_seq_id_2>
         <PDBx:dist>0.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>115</PDBx:auth_seq_id_2>
         <PDBx:dist>0.41</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>327</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>476</PDBx:auth_seq_id_2>
         <PDBx:dist>0.44</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>31</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>80</PDBx:auth_seq_id_2>
         <PDBx:dist>0.44</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="13">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>29</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:dist>0.46</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="14">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>186</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>299</PDBx:auth_seq_id_2>
         <PDBx:dist>0.49</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="15">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>261</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>525</PDBx:auth_seq_id_2>
         <PDBx:dist>0.49</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="16">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>301</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>436</PDBx:auth_seq_id_2>
         <PDBx:dist>0.51</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="17">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>27</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>28</PDBx:auth_seq_id_2>
         <PDBx:dist>0.53</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="18">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>242</PDBx:auth_seq_id_2>
         <PDBx:dist>0.53</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="19">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>144</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>0.54</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="20">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>304</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>311</PDBx:auth_seq_id_2>
         <PDBx:dist>0.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="21">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>78</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>93</PDBx:auth_seq_id_2>
         <PDBx:dist>0.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="22">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O5B</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>0.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="23">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>0.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="24">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>34</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>84</PDBx:auth_seq_id_2>
         <PDBx:dist>0.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="25">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>0.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="26">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>0.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="27">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>199</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>446</PDBx:auth_seq_id_2>
         <PDBx:dist>0.59</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="28">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>190</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>0.59</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="29">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>283</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>0.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="30">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>176</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>0.62</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="31">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>31</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>80</PDBx:auth_seq_id_2>
         <PDBx:dist>0.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="32">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>0.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="33">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>301</PDBx:auth_seq_id_2>
         <PDBx:dist>0.64</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="34">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>53</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>495</PDBx:auth_seq_id_2>
         <PDBx:dist>0.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="35">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>47</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>91</PDBx:auth_seq_id_2>
         <PDBx:dist>0.68</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="36">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C4B</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>0.69</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="37">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>275</PDBx:auth_seq_id_2>
         <PDBx:dist>0.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="38">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>147</PDBx:auth_seq_id_2>
         <PDBx:dist>0.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="39">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OH</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C6A</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>244</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>0.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="40">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C1D</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>0.71</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="41">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>145</PDBx:auth_seq_id_2>
         <PDBx:dist>0.71</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="42">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>0.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="43">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>9</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>333</PDBx:auth_seq_id_2>
         <PDBx:dist>0.73</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>2_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="44">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>475</PDBx:auth_seq_id_2>
         <PDBx:dist>0.73</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="45">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>74</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>130</PDBx:auth_seq_id_2>
         <PDBx:dist>0.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="46">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>283</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>0.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="47">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>373</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>496</PDBx:auth_seq_id_2>
         <PDBx:dist>0.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="48">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NH1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>110</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:dist>0.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="49">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>281</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>0.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="50">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>288</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>0.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="51">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>77</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>133</PDBx:auth_seq_id_2>
         <PDBx:dist>0.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="52">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>243</PDBx:auth_seq_id_2>
         <PDBx:dist>0.77</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="53">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>56</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>0.77</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="54">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>115</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>0.77</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="55">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>238</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>505</PDBx:auth_seq_id_2>
         <PDBx:dist>0.79</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="56">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>155</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>334</PDBx:auth_seq_id_2>
         <PDBx:dist>0.79</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="57">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>278</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>468</PDBx:auth_seq_id_2>
         <PDBx:dist>0.79</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="58">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>209</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>284</PDBx:auth_seq_id_2>
         <PDBx:dist>0.80</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="59">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>32</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>51</PDBx:auth_seq_id_2>
         <PDBx:dist>0.80</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="60">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OH</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>158</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>0.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="61">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>0.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="62">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>0.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="63">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>2</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:dist>0.82</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="64">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>121</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>0.83</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="65">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>8</PDBx:auth_seq_id_2>
         <PDBx:dist>0.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="66">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>0.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="67">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>121</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>0.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="68">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>261</PDBx:auth_seq_id_2>
         <PDBx:dist>0.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="69">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>8</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>0.86</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>2_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="70">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>0.86</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="71">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>143</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>0.86</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="72">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>174</PDBx:auth_seq_id_2>
         <PDBx:dist>0.86</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="73">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>0.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="74">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>303</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>0.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="75">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>5</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:dist>0.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="76">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>190</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>325</PDBx:auth_seq_id_2>
         <PDBx:dist>0.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="77">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>129</PDBx:auth_seq_id_2>
         <PDBx:dist>0.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="78">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>0.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="79">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>169</PDBx:auth_seq_id_2>
         <PDBx:dist>0.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="80">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>145</PDBx:auth_seq_id_2>
         <PDBx:dist>0.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="81">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NH2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>115</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>0.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="82">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>261</PDBx:auth_seq_id_2>
         <PDBx:dist>0.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="83">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>114</PDBx:auth_seq_id_2>
         <PDBx:dist>0.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="84">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>0.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="85">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>198</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>0.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="86">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>56</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>0.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="87">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>71</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>0.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="88">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>0.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="89">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>58</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>95</PDBx:auth_seq_id_2>
         <PDBx:dist>0.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="90">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>65</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>124</PDBx:auth_seq_id_2>
         <PDBx:dist>0.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="91">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>169</PDBx:auth_seq_id_2>
         <PDBx:dist>0.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="92">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>0.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="93">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>115</PDBx:auth_seq_id_2>
         <PDBx:dist>0.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="94">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>38</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>123</PDBx:auth_seq_id_2>
         <PDBx:dist>0.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="95">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>195</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>426</PDBx:auth_seq_id_2>
         <PDBx:dist>0.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="96">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>36</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>0.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="97">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>31</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>80</PDBx:auth_seq_id_2>
         <PDBx:dist>0.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="98">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>39</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>532</PDBx:auth_seq_id_2>
         <PDBx:dist>0.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="99">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>8</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>9</PDBx:auth_seq_id_2>
         <PDBx:dist>0.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="100">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>0.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="101">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>180</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>369</PDBx:auth_seq_id_2>
         <PDBx:dist>0.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="102">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>24</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>49</PDBx:auth_seq_id_2>
         <PDBx:dist>0.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="103">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>0.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="104">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>466</PDBx:auth_seq_id_2>
         <PDBx:dist>0.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="105">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>28</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>28</PDBx:auth_seq_id_2>
         <PDBx:dist>0.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="106">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>301</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>0.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="107">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>0.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="108">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>53</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>494</PDBx:auth_seq_id_2>
         <PDBx:dist>0.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="109">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>145</PDBx:auth_seq_id_2>
         <PDBx:dist>0.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="110">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>58</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>95</PDBx:auth_seq_id_2>
         <PDBx:dist>0.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="111">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>27</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>28</PDBx:auth_seq_id_2>
         <PDBx:dist>0.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="112">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>152</PDBx:auth_seq_id_2>
         <PDBx:dist>0.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="113">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>465</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:dist>0.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="114">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>18</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>0.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="115">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>38</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>126</PDBx:auth_seq_id_2>
         <PDBx:dist>0.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="116">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>12</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>177</PDBx:auth_seq_id_2>
         <PDBx:dist>0.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="117">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>26</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>50</PDBx:auth_seq_id_2>
         <PDBx:dist>0.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="118">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>302</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>0.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="119">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>2</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>545</PDBx:auth_seq_id_2>
         <PDBx:dist>0.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="120">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>131</PDBx:auth_seq_id_2>
         <PDBx:dist>0.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="121">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>0.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="122">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>303</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>0.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="123">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>0.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="124">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:dist>1.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="125">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>301</PDBx:auth_seq_id_2>
         <PDBx:dist>1.01</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="126">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>407</PDBx:auth_seq_id_2>
         <PDBx:dist>1.01</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="127">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>54</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>499</PDBx:auth_seq_id_2>
         <PDBx:dist>1.01</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="128">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.01</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="129">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>292</PDBx:auth_seq_id_2>
         <PDBx:dist>1.01</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="130">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>73</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>73</PDBx:auth_seq_id_2>
         <PDBx:dist>1.01</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="131">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>301</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>1.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="132">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="133">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>154</PDBx:auth_seq_id_2>
         <PDBx:dist>1.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="134">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C4D</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="135">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>243</PDBx:auth_seq_id_2>
         <PDBx:dist>1.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="136">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>481</PDBx:auth_seq_id_2>
         <PDBx:dist>1.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="137">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>62</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>94</PDBx:auth_seq_id_2>
         <PDBx:dist>1.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="138">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>184</PDBx:auth_seq_id_2>
         <PDBx:dist>1.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="139">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>388</PDBx:auth_seq_id_2>
         <PDBx:dist>1.03</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="140">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>265</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>1.03</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="141">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>262</PDBx:auth_seq_id_2>
         <PDBx:dist>1.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="142">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>264</PDBx:auth_seq_id_2>
         <PDBx:dist>1.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="143">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OH</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>262</PDBx:auth_seq_id_2>
         <PDBx:dist>1.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="144">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>138</PDBx:auth_seq_id_2>
         <PDBx:dist>1.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="145">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>266</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="146">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>71</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>1.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="147">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>186</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>441</PDBx:auth_seq_id_2>
         <PDBx:dist>1.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="148">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>262</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>368</PDBx:auth_seq_id_2>
         <PDBx:dist>1.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="149">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>121</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="150">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>114</PDBx:auth_seq_id_2>
         <PDBx:dist>1.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="151">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C2D</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="152">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>283</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>288</PDBx:auth_seq_id_2>
         <PDBx:dist>1.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="153">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>128</PDBx:auth_seq_id_2>
         <PDBx:dist>1.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="154">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>248</PDBx:auth_seq_id_2>
         <PDBx:dist>1.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="155">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>1.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="156">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="157">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>169</PDBx:auth_seq_id_2>
         <PDBx:dist>1.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="158">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>27</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>28</PDBx:auth_seq_id_2>
         <PDBx:dist>1.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="159">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>11</PDBx:auth_seq_id_2>
         <PDBx:dist>1.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="160">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>155</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>178</PDBx:auth_seq_id_2>
         <PDBx:dist>1.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="161">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>174</PDBx:auth_seq_id_2>
         <PDBx:dist>1.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="162">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>131</PDBx:auth_seq_id_2>
         <PDBx:dist>1.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="163">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CZ3</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>321</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>405</PDBx:auth_seq_id_2>
         <PDBx:dist>1.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="164">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>1.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="165">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>351</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>365</PDBx:auth_seq_id_2>
         <PDBx:dist>1.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="166">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>495</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>495</PDBx:auth_seq_id_2>
         <PDBx:dist>1.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="167">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>33</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>83</PDBx:auth_seq_id_2>
         <PDBx:dist>1.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="168">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>31</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>80</PDBx:auth_seq_id_2>
         <PDBx:dist>1.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="169">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>1.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="170">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>53</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>495</PDBx:auth_seq_id_2>
         <PDBx:dist>1.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="171">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>1.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="172">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>242</PDBx:auth_seq_id_2>
         <PDBx:dist>1.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="173">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>184</PDBx:auth_seq_id_2>
         <PDBx:dist>1.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="174">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>74</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>130</PDBx:auth_seq_id_2>
         <PDBx:dist>1.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="175">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>283</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>288</PDBx:auth_seq_id_2>
         <PDBx:dist>1.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="176">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>262</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>368</PDBx:auth_seq_id_2>
         <PDBx:dist>1.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="177">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N6A</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>83</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="178">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C5B</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="179">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>287</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>327</PDBx:auth_seq_id_2>
         <PDBx:dist>1.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="180">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>1.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="181">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>47</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>89</PDBx:auth_seq_id_2>
         <PDBx:dist>1.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="182">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>282</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>1.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="183">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="184">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>252</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>390</PDBx:auth_seq_id_2>
         <PDBx:dist>1.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="185">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>174</PDBx:auth_seq_id_2>
         <PDBx:dist>1.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="186">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>1.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="187">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>193</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>328</PDBx:auth_seq_id_2>
         <PDBx:dist>1.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="188">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>132</PDBx:auth_seq_id_2>
         <PDBx:dist>1.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="189">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>157</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>406</PDBx:auth_seq_id_2>
         <PDBx:dist>1.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="190">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>307</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>307</PDBx:auth_seq_id_2>
         <PDBx:dist>1.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_654</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="191">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>465</PDBx:auth_seq_id_2>
         <PDBx:dist>1.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="192">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>11</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>178</PDBx:auth_seq_id_2>
         <PDBx:dist>1.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="193">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="194">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="195">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="196">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>154</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>518</PDBx:auth_seq_id_2>
         <PDBx:dist>1.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="197">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>260</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="198">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>326</PDBx:auth_seq_id_2>
         <PDBx:dist>1.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="199">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="200">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>289</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>1.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="201">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OH</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>261</PDBx:auth_seq_id_2>
         <PDBx:dist>1.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="202">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>326</PDBx:auth_seq_id_2>
         <PDBx:dist>1.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="203">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>73</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>73</PDBx:auth_seq_id_2>
         <PDBx:dist>1.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="204">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>143</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="205">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>175</PDBx:auth_seq_id_2>
         <PDBx:dist>1.16</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="206">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:dist>1.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="207">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>1.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="208">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>30</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:dist>1.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="209">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>180</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>334</PDBx:auth_seq_id_2>
         <PDBx:dist>1.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="210">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>66</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>71</PDBx:auth_seq_id_2>
         <PDBx:dist>1.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="211">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>326</PDBx:auth_seq_id_2>
         <PDBx:dist>1.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="212">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>146</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>336</PDBx:auth_seq_id_2>
         <PDBx:dist>1.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="213">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>8</PDBx:auth_seq_id_2>
         <PDBx:dist>1.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="214">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>58</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>95</PDBx:auth_seq_id_2>
         <PDBx:dist>1.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="215">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>289</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>1.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="216">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>178</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="217">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>209</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>302</PDBx:auth_seq_id_2>
         <PDBx:dist>1.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="218">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>114</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>396</PDBx:auth_seq_id_2>
         <PDBx:dist>1.20</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="219">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>24</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>49</PDBx:auth_seq_id_2>
         <PDBx:dist>1.20</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="220">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.20</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="221">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>289</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>435</PDBx:auth_seq_id_2>
         <PDBx:dist>1.20</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="222">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>470</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>471</PDBx:auth_seq_id_2>
         <PDBx:dist>1.20</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="223">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>326</PDBx:auth_seq_id_2>
         <PDBx:dist>1.20</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="224">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>38</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>126</PDBx:auth_seq_id_2>
         <PDBx:dist>1.20</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="225">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>1.20</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="226">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>66</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>1.20</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="227">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>278</PDBx:auth_seq_id_2>
         <PDBx:dist>1.20</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="228">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NH2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>1.21</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="229">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.21</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="230">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>242</PDBx:auth_seq_id_2>
         <PDBx:dist>1.21</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="231">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:dist>1.21</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="232">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>146</PDBx:auth_seq_id_2>
         <PDBx:dist>1.21</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="233">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>310</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>463</PDBx:auth_seq_id_2>
         <PDBx:dist>1.21</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="234">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>163</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>326</PDBx:auth_seq_id_2>
         <PDBx:dist>1.22</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="235">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NH1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>54</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>1.22</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="236">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N3A</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.22</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="237">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>34</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>83</PDBx:auth_seq_id_2>
         <PDBx:dist>1.22</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="238">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>62</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>94</PDBx:auth_seq_id_2>
         <PDBx:dist>1.22</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="239">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>48</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>92</PDBx:auth_seq_id_2>
         <PDBx:dist>1.22</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="240">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.22</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="241">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.23</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="242">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>277</PDBx:auth_seq_id_2>
         <PDBx:dist>1.23</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="243">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>155</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>179</PDBx:auth_seq_id_2>
         <PDBx:dist>1.23</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="244">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>61</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>94</PDBx:auth_seq_id_2>
         <PDBx:dist>1.23</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="245">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>78</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>92</PDBx:auth_seq_id_2>
         <PDBx:dist>1.23</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="246">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>142</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:dist>1.23</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="247">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>543</PDBx:auth_seq_id_2>
         <PDBx:dist>1.23</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="248">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>189</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:dist>1.23</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="249">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OH</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>158</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.24</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="250">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>1.24</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="251">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>143</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.24</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="252">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>1.24</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="253">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>36</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>1.24</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="254">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>250</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>530</PDBx:auth_seq_id_2>
         <PDBx:dist>1.24</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="255">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>283</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>1.24</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="256">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>74</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>130</PDBx:auth_seq_id_2>
         <PDBx:dist>1.24</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="257">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>124</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.24</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="258">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>1.25</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="259">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.25</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="260">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>297</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>329</PDBx:auth_seq_id_2>
         <PDBx:dist>1.25</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="261">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>147</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>1.25</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="262">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.25</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="263">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>1.25</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="264">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>266</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.25</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="265">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>143</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.25</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="266">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>73</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>73</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="267">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="268">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>32</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>51</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="269">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="270">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>69</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="271">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>287</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>327</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="272">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="273">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NH1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="274">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>146</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="275">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>206</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="276">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>174</PDBx:auth_seq_id_2>
         <PDBx:dist>1.26</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="277">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>178</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="278">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N9A</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="279">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>8</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>2_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="280">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="281">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>278</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="282">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>62</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>94</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="283">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O4B</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="284">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>62</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>94</PDBx:auth_seq_id_2>
         <PDBx:dist>1.27</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="285">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>149</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>156</PDBx:auth_seq_id_2>
         <PDBx:dist>1.28</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="286">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>147</PDBx:auth_seq_id_2>
         <PDBx:dist>1.28</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="287">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>137</PDBx:auth_seq_id_2>
         <PDBx:dist>1.28</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="288">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>1.29</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="289">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>325</PDBx:auth_seq_id_2>
         <PDBx:dist>1.29</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="290">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>171</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>444</PDBx:auth_seq_id_2>
         <PDBx:dist>1.29</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="291">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>132</PDBx:auth_seq_id_2>
         <PDBx:dist>1.29</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="292">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>115</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>1.29</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="293">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>193</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>329</PDBx:auth_seq_id_2>
         <PDBx:dist>1.30</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="294">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>129</PDBx:auth_seq_id_2>
         <PDBx:dist>1.30</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="295">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>228</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>429</PDBx:auth_seq_id_2>
         <PDBx:dist>1.30</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="296">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>265</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>292</PDBx:auth_seq_id_2>
         <PDBx:dist>1.31</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="297">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>61</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>94</PDBx:auth_seq_id_2>
         <PDBx:dist>1.31</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="298">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>144</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>515</PDBx:auth_seq_id_2>
         <PDBx:dist>1.31</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="299">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>1.32</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="300">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>74</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>130</PDBx:auth_seq_id_2>
         <PDBx:dist>1.32</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="301">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>289</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>1.32</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="302">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>174</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>442</PDBx:auth_seq_id_2>
         <PDBx:dist>1.32</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="303">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>168</PDBx:auth_seq_id_2>
         <PDBx:dist>1.32</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="304">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>283</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>288</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="305">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>114</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="306">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>143</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="307">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>82</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>246</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="308">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>325</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="309">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>115</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="310">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>292</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="311">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>77</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>133</PDBx:auth_seq_id_2>
         <PDBx:dist>1.33</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="312">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>137</PDBx:auth_seq_id_2>
         <PDBx:dist>1.34</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="313">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>64</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>121</PDBx:auth_seq_id_2>
         <PDBx:dist>1.34</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="314">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>1.34</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="315">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>83</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>348</PDBx:auth_seq_id_2>
         <PDBx:dist>1.34</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="316">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>53</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>494</PDBx:auth_seq_id_2>
         <PDBx:dist>1.34</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="317">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>36</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>86</PDBx:auth_seq_id_2>
         <PDBx:dist>1.34</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="318">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C5B</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.34</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="319">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>277</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>302</PDBx:auth_seq_id_2>
         <PDBx:dist>1.35</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="320">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>64</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>121</PDBx:auth_seq_id_2>
         <PDBx:dist>1.35</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="321">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>2</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:dist>1.35</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="322">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>66</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>71</PDBx:auth_seq_id_2>
         <PDBx:dist>1.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="323">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>118</PDBx:auth_seq_id_2>
         <PDBx:dist>1.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="324">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>169</PDBx:auth_seq_id_2>
         <PDBx:dist>1.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="325">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>48</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>92</PDBx:auth_seq_id_2>
         <PDBx:dist>1.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="326">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>173</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>386</PDBx:auth_seq_id_2>
         <PDBx:dist>1.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="327">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>190</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>325</PDBx:auth_seq_id_2>
         <PDBx:dist>1.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="328">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>62</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>94</PDBx:auth_seq_id_2>
         <PDBx:dist>1.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="329">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>271</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>329</PDBx:auth_seq_id_2>
         <PDBx:dist>1.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="330">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>12</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>273</PDBx:auth_seq_id_2>
         <PDBx:dist>1.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="331">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>114</PDBx:auth_seq_id_2>
         <PDBx:dist>1.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="332">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>2</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>543</PDBx:auth_seq_id_2>
         <PDBx:dist>1.36</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="333">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>1.37</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="334">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>12</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>273</PDBx:auth_seq_id_2>
         <PDBx:dist>1.37</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="335">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>306</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>453</PDBx:auth_seq_id_2>
         <PDBx:dist>1.37</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="336">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>61</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>94</PDBx:auth_seq_id_2>
         <PDBx:dist>1.37</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="337">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>158</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.37</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="338">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>11</PDBx:auth_seq_id_2>
         <PDBx:dist>1.37</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="339">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>87</PDBx:auth_seq_id_2>
         <PDBx:dist>1.37</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="340">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>190</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="341">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="342">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>186</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>299</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="343">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>178</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="344">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>173</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="345">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="346">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="347">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="348">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>120</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="349">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NH2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="350">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>143</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="351">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>42</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>122</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="352">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>151</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="353">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>1.38</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="354">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.39</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="355">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>115</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>1.39</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="356">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>277</PDBx:auth_seq_id_2>
         <PDBx:dist>1.39</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="357">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>1.39</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="358">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>18</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.39</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="359">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.39</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="360">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>31</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>80</PDBx:auth_seq_id_2>
         <PDBx:dist>1.39</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="361">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>301</PDBx:auth_seq_id_2>
         <PDBx:dist>1.39</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="362">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>198</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>1.39</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="363">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>168</PDBx:auth_seq_id_2>
         <PDBx:dist>1.39</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="364">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.40</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="365">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>83</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>348</PDBx:auth_seq_id_2>
         <PDBx:dist>1.40</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="366">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>78</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>93</PDBx:auth_seq_id_2>
         <PDBx:dist>1.40</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="367">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>155</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>178</PDBx:auth_seq_id_2>
         <PDBx:dist>1.40</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="368">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>283</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>1.40</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="369">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>1.40</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="370">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>27</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>28</PDBx:auth_seq_id_2>
         <PDBx:dist>1.40</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="371">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.40</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="372">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>97</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>1.40</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="373">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>482</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>482</PDBx:auth_seq_id_2>
         <PDBx:dist>1.41</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="374">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NH1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>1.41</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="375">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>71</PDBx:auth_seq_id_2>
         <PDBx:dist>1.41</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="376">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>400</PDBx:auth_seq_id_2>
         <PDBx:dist>1.41</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="377">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>9</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>333</PDBx:auth_seq_id_2>
         <PDBx:dist>1.41</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>2_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="378">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.41</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="379">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>155</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>518</PDBx:auth_seq_id_2>
         <PDBx:dist>1.41</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="380">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>387</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>573</PDBx:auth_seq_id_2>
         <PDBx:dist>1.41</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="381">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>146</PDBx:auth_seq_id_2>
         <PDBx:dist>1.41</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="382">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>132</PDBx:auth_seq_id_2>
         <PDBx:dist>1.41</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="383">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>274</PDBx:auth_seq_id_2>
         <PDBx:dist>1.42</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="384">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>77</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>133</PDBx:auth_seq_id_2>
         <PDBx:dist>1.42</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="385">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>145</PDBx:auth_seq_id_2>
         <PDBx:dist>1.42</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="386">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>278</PDBx:auth_seq_id_2>
         <PDBx:dist>1.42</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="387">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>289</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>1.42</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="388">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>34</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>84</PDBx:auth_seq_id_2>
         <PDBx:dist>1.43</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="389">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>282</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>288</PDBx:auth_seq_id_2>
         <PDBx:dist>1.43</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="390">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>144</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.43</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="391">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:dist>1.43</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="392">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>60</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>137</PDBx:auth_seq_id_2>
         <PDBx:dist>1.43</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="393">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>180</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>334</PDBx:auth_seq_id_2>
         <PDBx:dist>1.43</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="394">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:dist>1.43</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="395">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>38</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>123</PDBx:auth_seq_id_2>
         <PDBx:dist>1.43</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="396">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>69</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>376</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="397">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="398">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>138</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="399">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>18</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>262</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="400">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="401">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>38</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>531</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="402">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>155</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>180</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="403">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>131</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="404">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>37</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="405">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>273</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>1.44</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="406">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>178</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>273</PDBx:auth_seq_id_2>
         <PDBx:dist>1.45</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="407">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>292</PDBx:auth_seq_id_2>
         <PDBx:dist>1.45</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="408">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>31</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>80</PDBx:auth_seq_id_2>
         <PDBx:dist>1.45</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="409">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>110</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>168</PDBx:auth_seq_id_2>
         <PDBx:dist>1.45</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="410">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>155</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>180</PDBx:auth_seq_id_2>
         <PDBx:dist>1.45</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="411">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>325</PDBx:auth_seq_id_2>
         <PDBx:dist>1.45</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="412">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>325</PDBx:auth_seq_id_2>
         <PDBx:dist>1.45</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="413">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>243</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="414">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="415">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>79</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>95</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="416">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>5</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="417">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>301</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="418">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>243</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="419">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>174</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="420">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>507</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="421">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>274</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="422">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>120</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.46</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="423">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>12</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>177</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="424">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>262</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>350</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="425">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>24</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>49</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="426">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="427">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>84</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="428">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>275</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>313</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="429">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="430">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>18</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="431">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>5</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:dist>1.47</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="432">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CH2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>321</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>405</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="433">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>69</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="434">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>25</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>50</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="435">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>143</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="436">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>115</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="437">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>42</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>392</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="438">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>127</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="439">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>8</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="440">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>8</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>8</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="441">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>62</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>94</PDBx:auth_seq_id_2>
         <PDBx:dist>1.48</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="442">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>281</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>1.49</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="443">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>304</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>311</PDBx:auth_seq_id_2>
         <PDBx:dist>1.49</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="444">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>82</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>1.49</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="445">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>1.49</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="446">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>1.49</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="447">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>48</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>92</PDBx:auth_seq_id_2>
         <PDBx:dist>1.49</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="448">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>56</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>100</PDBx:auth_seq_id_2>
         <PDBx:dist>1.49</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="449">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>104</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>237</PDBx:auth_seq_id_2>
         <PDBx:dist>1.50</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="450">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>149</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>297</PDBx:auth_seq_id_2>
         <PDBx:dist>1.50</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="451">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>277</PDBx:auth_seq_id_2>
         <PDBx:dist>1.50</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="452">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>38</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>529</PDBx:auth_seq_id_2>
         <PDBx:dist>1.50</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="453">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>206</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.50</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="454">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>9</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>1.50</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="455">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>248</PDBx:auth_seq_id_2>
         <PDBx:dist>1.50</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="456">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OH</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>83</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>348</PDBx:auth_seq_id_2>
         <PDBx:dist>1.50</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="457">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>154</PDBx:auth_seq_id_2>
         <PDBx:dist>1.50</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="458">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>274</PDBx:auth_seq_id_2>
         <PDBx:dist>1.51</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="459">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>1.51</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="460">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>47</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>90</PDBx:auth_seq_id_2>
         <PDBx:dist>1.51</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="461">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CH2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>1.51</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="462">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>277</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>302</PDBx:auth_seq_id_2>
         <PDBx:dist>1.51</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="463">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>2</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>545</PDBx:auth_seq_id_2>
         <PDBx:dist>1.51</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="464">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>2</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>545</PDBx:auth_seq_id_2>
         <PDBx:dist>1.51</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="465">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>276</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>313</PDBx:auth_seq_id_2>
         <PDBx:dist>1.52</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="466">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>157</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>522</PDBx:auth_seq_id_2>
         <PDBx:dist>1.52</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="467">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>78</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>134</PDBx:auth_seq_id_2>
         <PDBx:dist>1.52</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="468">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>253</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>526</PDBx:auth_seq_id_2>
         <PDBx:dist>1.52</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="469">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>1.52</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="470">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>87</PDBx:auth_seq_id_2>
         <PDBx:dist>1.53</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="471">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>274</PDBx:auth_seq_id_2>
         <PDBx:dist>1.53</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="472">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>1.53</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="473">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>209</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>302</PDBx:auth_seq_id_2>
         <PDBx:dist>1.53</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="474">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>85</PDBx:auth_seq_id_2>
         <PDBx:dist>1.53</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="475">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>115</PDBx:auth_seq_id_2>
         <PDBx:dist>1.53</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="476">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>119</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>254</PDBx:auth_seq_id_2>
         <PDBx:dist>1.53</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="477">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>120</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.54</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="478">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>304</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>1.54</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="479">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>74</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>130</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="480">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>OXM</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>332</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="481">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>262</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="482">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="483">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="484">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>181</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>369</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="485">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>39</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>484</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="486">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>304</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="487">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>58</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>95</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="488">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>115</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="489">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>175</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="490">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>1.55</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="491">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>141</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="492">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>280</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="493">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>29</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="494">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>243</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>506</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="495">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>121</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="496">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>281</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="497">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>325</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="498">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>84</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="499">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="500">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>507</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="501">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NH2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>171</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>424</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="502">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="503">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="504">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>324</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>475</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="505">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>30</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="506">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>12</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="507">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>276</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>313</PDBx:auth_seq_id_2>
         <PDBx:dist>1.56</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="508">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>242</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="509">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>278</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>468</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="510">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="511">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>284</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="512">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="513">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="514">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>176</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="515">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>190</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="516">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>479</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="517">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>279</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>547</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="518">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>153</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="519">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>37</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>1.57</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="520">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OH</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>158</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="521">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>29</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>51</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="522">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>71</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>345</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="523">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>31</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>80</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="524">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>243</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="525">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O3</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>OXM</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>332</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>424</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="526">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>281</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="527">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CH2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="528">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>290</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>327</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="529">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>8</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>9</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="530">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>131</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="531">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NH2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>18</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>261</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="532">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>66</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="533">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>84</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.58</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="534">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>1.59</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="535">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>292</PDBx:auth_seq_id_2>
         <PDBx:dist>1.59</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="536">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>29</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>51</PDBx:auth_seq_id_2>
         <PDBx:dist>1.59</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="537">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>279</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>310</PDBx:auth_seq_id_2>
         <PDBx:dist>1.59</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="538">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>277</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>302</PDBx:auth_seq_id_2>
         <PDBx:dist>1.59</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="539">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>286</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>577</PDBx:auth_seq_id_2>
         <PDBx:dist>1.59</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="540">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.59</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="541">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>145</PDBx:auth_seq_id_2>
         <PDBx:dist>1.59</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="542">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NH1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>112</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>354</PDBx:auth_seq_id_2>
         <PDBx:dist>1.59</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="543">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.59</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="544">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>115</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="545">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>10</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>333</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="546">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="547">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>97</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="548">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>264</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="549">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>432</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="550">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>285</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>470</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="551">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>154</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="552">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>288</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>437</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="553">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="554">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>152</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="555">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>11</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>155</PDBx:auth_seq_id_2>
         <PDBx:dist>1.60</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="556">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="557">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>154</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>519</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="558">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>69</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>71</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="559">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>114</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="560">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>142</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>185</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="561">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>517</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="562">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>156</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>406</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="563">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>304</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>314</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="564">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="565">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>132</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="566">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>184</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>470</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="567">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>34</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>83</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="568">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>1.61</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="569">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>328</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>419</PDBx:auth_seq_id_2>
         <PDBx:dist>1.62</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="570">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>5</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>5</PDBx:auth_seq_id_2>
         <PDBx:dist>1.62</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="571">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>39</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>87</PDBx:auth_seq_id_2>
         <PDBx:dist>1.62</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="572">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>1.62</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="573">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O5B</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.62</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="574">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>97</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>1.62</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="575">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>175</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.62</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="576">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>304</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>458</PDBx:auth_seq_id_2>
         <PDBx:dist>1.62</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="577">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>208</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>303</PDBx:auth_seq_id_2>
         <PDBx:dist>1.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="578">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>29</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:dist>1.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="579">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>304</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>314</PDBx:auth_seq_id_2>
         <PDBx:dist>1.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="580">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>292</PDBx:auth_seq_id_2>
         <PDBx:dist>1.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="581">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>183</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>336</PDBx:auth_seq_id_2>
         <PDBx:dist>1.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="582">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="583">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>280</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>302</PDBx:auth_seq_id_2>
         <PDBx:dist>1.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="584">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>47</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>89</PDBx:auth_seq_id_2>
         <PDBx:dist>1.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="585">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C3D</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="586">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>124</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="587">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>1.63</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="588">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>370</PDBx:auth_seq_id_2>
         <PDBx:dist>1.64</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="589">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>277</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>302</PDBx:auth_seq_id_2>
         <PDBx:dist>1.64</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="590">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>1.64</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="591">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C3D</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>56</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.64</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="592">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>1.64</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="593">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>281</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>1.64</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="594">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>124</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.64</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="595">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NH1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>110</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:dist>1.65</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="596">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>208</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>301</PDBx:auth_seq_id_2>
         <PDBx:dist>1.65</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="597">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>281</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>309</PDBx:auth_seq_id_2>
         <PDBx:dist>1.65</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="598">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>1.65</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="599">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CH2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CH2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>247</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.65</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="600">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="601">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>176</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="602">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>84</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>246</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="603">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="604">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>274</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="605">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>154</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="606">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>146</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="607">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>127</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="608">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="609">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="610">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>127</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="611">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>279</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>553</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="612">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>310</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="613">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>77</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>134</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="614">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>260</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>263</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="615">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>243</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="616">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>78</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>93</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="617">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>86</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="618">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>311</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>552</PDBx:auth_seq_id_2>
         <PDBx:dist>1.66</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="619">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>303</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>1.67</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="620">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>1.67</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="621">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>186</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>1.67</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="622">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>1.67</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="623">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.67</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="624">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OH</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N7A</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>244</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.67</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="625">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>250</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>530</PDBx:auth_seq_id_2>
         <PDBx:dist>1.68</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="626">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.68</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="627">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>277</PDBx:auth_seq_id_2>
         <PDBx:dist>1.68</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="628">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>313</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>541</PDBx:auth_seq_id_2>
         <PDBx:dist>1.68</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="629">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>168</PDBx:auth_seq_id_2>
         <PDBx:dist>1.68</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="630">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>185</PDBx:auth_seq_id_2>
         <PDBx:dist>1.68</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="631">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.68</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="632">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>68</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>400</PDBx:auth_seq_id_2>
         <PDBx:dist>1.68</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="633">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>1.68</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="634">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>106</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>356</PDBx:auth_seq_id_2>
         <PDBx:dist>1.68</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="635">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>481</PDBx:auth_seq_id_2>
         <PDBx:dist>1.68</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="636">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>136</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>383</PDBx:auth_seq_id_2>
         <PDBx:dist>1.69</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="637">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>262</PDBx:auth_seq_id_2>
         <PDBx:dist>1.69</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="638">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>293</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>481</PDBx:auth_seq_id_2>
         <PDBx:dist>1.69</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="639">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>111</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>480</PDBx:auth_seq_id_2>
         <PDBx:dist>1.69</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="640">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>141</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>176</PDBx:auth_seq_id_2>
         <PDBx:dist>1.69</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="641">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>111</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>1.69</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="642">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>209</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>1.69</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="643">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>146</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>336</PDBx:auth_seq_id_2>
         <PDBx:dist>1.69</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="644">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>120</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.69</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="645">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>82</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>246</PDBx:auth_seq_id_2>
         <PDBx:dist>1.69</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="646">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>42</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>122</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="647">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>184</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="648">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="649">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>147</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="650">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>128</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="651">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>147</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="652">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>47</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>90</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="653">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>90</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="654">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="655">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>128</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="656">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="657">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>145</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="658">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="659">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="660">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>129</PDBx:auth_seq_id_2>
         <PDBx:dist>1.70</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="661">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>124</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.71</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="662">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>62</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>133</PDBx:auth_seq_id_2>
         <PDBx:dist>1.71</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="663">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>132</PDBx:auth_seq_id_2>
         <PDBx:dist>1.71</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="664">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>1.71</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="665">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.71</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="666">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>130</PDBx:auth_seq_id_2>
         <PDBx:dist>1.71</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="667">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>281</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>309</PDBx:auth_seq_id_2>
         <PDBx:dist>1.71</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="668">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>475</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="669">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>280</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="670">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="671">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="672">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="673">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>143</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="674">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>465</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="675">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="676">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>27</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>28</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="677">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="678">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>122</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="679">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>301</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="680">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>56</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="681">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>119</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>262</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="682">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>157</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>522</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="683">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>121</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="684">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>58</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>96</PDBx:auth_seq_id_2>
         <PDBx:dist>1.72</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="685">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>137</PDBx:auth_seq_id_2>
         <PDBx:dist>1.73</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="686">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>157</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>406</PDBx:auth_seq_id_2>
         <PDBx:dist>1.73</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="687">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>185</PDBx:auth_seq_id_2>
         <PDBx:dist>1.73</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="688">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>69</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>1.73</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="689">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>186</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>1.73</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="690">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>271</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>329</PDBx:auth_seq_id_2>
         <PDBx:dist>1.73</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="691">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O2N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>58</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.74</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="692">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>32</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>80</PDBx:auth_seq_id_2>
         <PDBx:dist>1.74</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="693">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>262</PDBx:auth_seq_id_2>
         <PDBx:dist>1.74</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="694">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>18</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.74</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="695">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>184</PDBx:auth_seq_id_2>
         <PDBx:dist>1.74</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="696">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>47</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>91</PDBx:auth_seq_id_2>
         <PDBx:dist>1.74</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="697">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>242</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="698">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>52</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>492</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="699">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="700">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="701">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>129</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="702">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>69</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>154</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="703">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="704">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>183</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>370</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="705">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>48</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>92</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="706">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="707">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>303</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>434</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="708">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.75</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="709">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>149</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>287</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="710">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>236</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>328</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="711">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="712">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>264</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="713">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>30</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>82</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="714">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>104</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>237</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="715">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="716">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="717">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>115</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="718">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>186</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>299</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="719">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>12</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>178</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="720">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="721">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>194</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>325</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="722">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="723">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>11</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>155</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="724">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>185</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>393</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="725">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>288</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="726">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>173</PDBx:auth_seq_id_2>
         <PDBx:dist>1.76</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="727">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>137</PDBx:auth_seq_id_2>
         <PDBx:dist>1.77</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="728">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>2</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>465</PDBx:auth_seq_id_2>
         <PDBx:dist>1.77</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="729">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.77</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="730">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>253</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>527</PDBx:auth_seq_id_2>
         <PDBx:dist>1.77</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="731">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>276</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>278</PDBx:auth_seq_id_2>
         <PDBx:dist>1.77</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="732">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>60</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>137</PDBx:auth_seq_id_2>
         <PDBx:dist>1.77</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="733">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>1.78</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="734">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>65</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>124</PDBx:auth_seq_id_2>
         <PDBx:dist>1.78</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="735">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>301</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.78</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="736">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>1.78</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="737">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O2A</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>54</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.78</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="738">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.78</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="739">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>277</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>302</PDBx:auth_seq_id_2>
         <PDBx:dist>1.78</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="740">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>283</PDBx:auth_seq_id_2>
         <PDBx:dist>1.78</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="741">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>350</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>368</PDBx:auth_seq_id_2>
         <PDBx:dist>1.78</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="742">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>1.78</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="743">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>139</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>398</PDBx:auth_seq_id_2>
         <PDBx:dist>1.79</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="744">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>8</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>9</PDBx:auth_seq_id_2>
         <PDBx:dist>1.79</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="745">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>206</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>1.79</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="746">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
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         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.79</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="747">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>44</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>484</PDBx:auth_seq_id_2>
         <PDBx:dist>1.79</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="748">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>128</PDBx:auth_seq_id_2>
         <PDBx:dist>1.79</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>61</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>124</PDBx:auth_seq_id_2>
         <PDBx:dist>1.79</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>545</PDBx:auth_seq_id_2>
         <PDBx:dist>1.79</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="751">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>38</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>119</PDBx:auth_seq_id_2>
         <PDBx:dist>1.79</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>329</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>394</PDBx:auth_seq_id_2>
         <PDBx:dist>1.80</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="753">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N1A</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>NAD</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>330</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>496</PDBx:auth_seq_id_2>
         <PDBx:dist>1.80</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="754">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>190</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>1.80</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="755">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>299</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>476</PDBx:auth_seq_id_2>
         <PDBx:dist>1.80</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="756">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>149</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>271</PDBx:auth_seq_id_2>
         <PDBx:dist>1.80</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="757">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>66</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>71</PDBx:auth_seq_id_2>
         <PDBx:dist>1.80</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="758">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C1B</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.80</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="759">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>58</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>95</PDBx:auth_seq_id_2>
         <PDBx:dist>1.80</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="760">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OH</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>261</PDBx:auth_seq_id_2>
         <PDBx:dist>1.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="761">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>310</PDBx:auth_seq_id_2>
         <PDBx:dist>1.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="762">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
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         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>173</PDBx:auth_seq_id_2>
         <PDBx:dist>1.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="763">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
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         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>128</PDBx:auth_seq_id_2>
         <PDBx:dist>1.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="764">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NH2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>54</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>1.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="765">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C4A</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="766">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C4B</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="767">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>11</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>178</PDBx:auth_seq_id_2>
         <PDBx:dist>1.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="768">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>1.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="769">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>186</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>441</PDBx:auth_seq_id_2>
         <PDBx:dist>1.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="770">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="771">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>46</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>130</PDBx:auth_seq_id_2>
         <PDBx:dist>1.81</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="772">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>112</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>354</PDBx:auth_seq_id_2>
         <PDBx:dist>1.82</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="773">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>12</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>178</PDBx:auth_seq_id_2>
         <PDBx:dist>1.82</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="774">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.82</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="775">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>148</PDBx:auth_seq_id_2>
         <PDBx:dist>1.82</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="776">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>65</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>1.82</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="777">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>77</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>133</PDBx:auth_seq_id_2>
         <PDBx:dist>1.82</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="778">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>8</PDBx:auth_seq_id_2>
         <PDBx:dist>1.82</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="779">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C1B</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.82</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="780">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>310</PDBx:auth_seq_id_2>
         <PDBx:dist>1.82</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="781">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>66</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>1.82</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="782">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>176</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>1.83</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="783">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>309</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>1.83</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="784">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>34</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>84</PDBx:auth_seq_id_2>
         <PDBx:dist>1.83</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="785">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>19</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>90</PDBx:auth_seq_id_2>
         <PDBx:dist>1.83</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="786">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>120</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>242</PDBx:auth_seq_id_2>
         <PDBx:dist>1.83</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="787">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
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         <PDBx:dist>1.83</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>111</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>292</PDBx:auth_seq_id_2>
         <PDBx:dist>1.83</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="789">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>63</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>143</PDBx:auth_seq_id_2>
         <PDBx:dist>1.83</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>288</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>1.83</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="791">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>304</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>311</PDBx:auth_seq_id_2>
         <PDBx:dist>1.83</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>303</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>1.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="793">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>139</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>402</PDBx:auth_seq_id_2>
         <PDBx:dist>1.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>131</PDBx:auth_seq_id_2>
         <PDBx:dist>1.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="795">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>209</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>317</PDBx:auth_seq_id_2>
         <PDBx:dist>1.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="796">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>299</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>327</PDBx:auth_seq_id_2>
         <PDBx:dist>1.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="797">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>181</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>369</PDBx:auth_seq_id_2>
         <PDBx:dist>1.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="798">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>206</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="799">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>301</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="800">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>42</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>122</PDBx:auth_seq_id_2>
         <PDBx:dist>1.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="801">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
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         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>1.84</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="802">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_atom_id_1>SD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
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         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
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         <PDBx:dist>1.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
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         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
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         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
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      <PDBx:pdbx_validate_symm_contact id="805">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:dist>1.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
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      <PDBx:pdbx_validate_symm_contact id="806">
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         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
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         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
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         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="807">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="808">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>146</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>336</PDBx:auth_seq_id_2>
         <PDBx:dist>1.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="809">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>208</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>451</PDBx:auth_seq_id_2>
         <PDBx:dist>1.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="810">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>9</PDBx:auth_seq_id_2>
         <PDBx:dist>1.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="811">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>274</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>478</PDBx:auth_seq_id_2>
         <PDBx:dist>1.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>15_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="812">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>302</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>1.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="813">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="814">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>289</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>1.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="815">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>64</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>121</PDBx:auth_seq_id_2>
         <PDBx:dist>1.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="816">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>361</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>384</PDBx:auth_seq_id_2>
         <PDBx:dist>1.85</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="817">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.86</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="818">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>18</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.86</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="819">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>1.86</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="820">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>53</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>53</PDBx:auth_seq_id_2>
         <PDBx:dist>1.86</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="821">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>1.86</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="822">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>91</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>342</PDBx:auth_seq_id_2>
         <PDBx:dist>1.86</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="823">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>56</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>1.86</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="824">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>155</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>180</PDBx:auth_seq_id_2>
         <PDBx:dist>1.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="825">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OH</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>287</PDBx:auth_seq_id_2>
         <PDBx:dist>1.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="826">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>154</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>1.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="827">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>132</PDBx:auth_seq_id_2>
         <PDBx:dist>1.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="828">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>54</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>499</PDBx:auth_seq_id_2>
         <PDBx:dist>1.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="829">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NH1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>1.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="830">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>297</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>397</PDBx:auth_seq_id_2>
         <PDBx:dist>1.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="831">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>313</PDBx:auth_seq_id_2>
         <PDBx:dist>1.87</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="832">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O2D</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="833">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>122</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>258</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="834">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>305</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="835">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>145</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="836">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>119</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>262</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="837">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>91</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>342</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="838">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>109</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="839">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="840">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>90</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="841">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="842">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>274</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="843">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>146</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="844">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>142</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="845">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>286</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>576</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="846">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>10</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="847">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>326</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="848">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NH2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>18</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>261</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="849">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>251</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>390</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="850">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>31</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>80</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="851">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>311</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="852">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>280</PDBx:auth_seq_id_2>
         <PDBx:dist>1.88</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="853">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>206</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>1.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="854">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>148</PDBx:auth_seq_id_2>
         <PDBx:dist>1.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="855">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>121</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="856">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>262</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>350</PDBx:auth_seq_id_2>
         <PDBx:dist>1.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="857">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>52</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>492</PDBx:auth_seq_id_2>
         <PDBx:dist>1.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="858">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>117</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="859">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>105</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>173</PDBx:auth_seq_id_2>
         <PDBx:dist>1.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="860">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>143</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>1.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="861">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>169</PDBx:auth_seq_id_2>
         <PDBx:dist>1.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="862">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>132</PDBx:auth_seq_id_2>
         <PDBx:dist>1.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="863">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>1.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="864">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>85</PDBx:auth_seq_id_2>
         <PDBx:dist>1.89</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="865">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>1.90</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="866">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>279</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>309</PDBx:auth_seq_id_2>
         <PDBx:dist>1.90</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="867">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>61</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>94</PDBx:auth_seq_id_2>
         <PDBx:dist>1.90</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="868">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>75</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>157</PDBx:auth_seq_id_2>
         <PDBx:dist>1.90</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="869">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OH</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>278</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>282</PDBx:auth_seq_id_2>
         <PDBx:dist>1.90</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="870">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>314</PDBx:auth_seq_id_2>
         <PDBx:dist>1.90</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="871">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>317</PDBx:auth_seq_id_2>
         <PDBx:dist>1.90</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="872">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>1.90</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="873">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>208</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>301</PDBx:auth_seq_id_2>
         <PDBx:dist>1.90</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="874">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>275</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>313</PDBx:auth_seq_id_2>
         <PDBx:dist>1.90</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="875">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>183</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>336</PDBx:auth_seq_id_2>
         <PDBx:dist>1.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="876">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>97</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>1.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="877">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>1.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="878">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>1.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="879">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>131</PDBx:auth_seq_id_2>
         <PDBx:dist>1.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="880">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>1.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="881">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>62</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>135</PDBx:auth_seq_id_2>
         <PDBx:dist>1.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="882">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>1.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="883">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>299</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>415</PDBx:auth_seq_id_2>
         <PDBx:dist>1.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="884">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>148</PDBx:auth_seq_id_2>
         <PDBx:dist>1.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="885">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>11</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>178</PDBx:auth_seq_id_2>
         <PDBx:dist>1.91</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="886">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>146</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="887">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>PN</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>58</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="888">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="889">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>274</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="890">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>37</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>535</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="891">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>34</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>83</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="892">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>206</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="893">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="894">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>304</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="895">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>147</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="896">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>303</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="897">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>149</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>156</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="898">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>SG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>77</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>131</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="899">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>127</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="900">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="901">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>97</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>242</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="902">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>47</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>90</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="903">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>69</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="904">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>32</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>51</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="905">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>111</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>292</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="906">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>311</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="907">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>285</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>471</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="908">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>32</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>51</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="909">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="910">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>174</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="911">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>87</PDBx:auth_seq_id_2>
         <PDBx:dist>1.93</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="912">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>29</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="913">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>307</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>307</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_654</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="914">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>142</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>175</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="915">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>47</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>91</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="916">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>91</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>342</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="917">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="918">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>142</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="919">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>292</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="920">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="921">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="922">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>8</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>2_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="923">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>110</PDBx:auth_seq_id_2>
         <PDBx:dist>1.94</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="924">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>302</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>317</PDBx:auth_seq_id_2>
         <PDBx:dist>1.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="925">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>68</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>400</PDBx:auth_seq_id_2>
         <PDBx:dist>1.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="926">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>64</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="927">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>112</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>248</PDBx:auth_seq_id_2>
         <PDBx:dist>1.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="928">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>1.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="929">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>124</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="930">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>129</PDBx:auth_seq_id_2>
         <PDBx:dist>1.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="931">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>83</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>348</PDBx:auth_seq_id_2>
         <PDBx:dist>1.95</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="932">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>32</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>51</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="933">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>115</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>255</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="934">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="935">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>64</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>125</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="936">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>168</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="937">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="938">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>282</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="939">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>197</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>325</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="940">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>206</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="941">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>8</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="942">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>208</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="943">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>87</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="944">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>145</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="945">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>38</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>123</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="946">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>209</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>302</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="947">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>160</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>328</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="948">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>82</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>242</PDBx:auth_seq_id_2>
         <PDBx:dist>1.96</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="949">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>1.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="950">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>1.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="951">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>407</PDBx:auth_seq_id_2>
         <PDBx:dist>1.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="952">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>532</PDBx:auth_seq_id_2>
         <PDBx:dist>1.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="953">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>122</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="954">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="955">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>142</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>185</PDBx:auth_seq_id_2>
         <PDBx:dist>1.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="956">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>1.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="957">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>189</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>440</PDBx:auth_seq_id_2>
         <PDBx:dist>1.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="958">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>82</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>246</PDBx:auth_seq_id_2>
         <PDBx:dist>1.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="959">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>286</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>577</PDBx:auth_seq_id_2>
         <PDBx:dist>1.97</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="960">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>85</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="961">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>264</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="962">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NH1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>110</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="963">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>82</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>246</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="964">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>25</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>49</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="965">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>104</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>237</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="966">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>259</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>422</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="967">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>28</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="968">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>266</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="969">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>90</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="970">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>74</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>130</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="971">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="972">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C4D</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="973">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>114</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="974">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>156</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>522</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="975">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>147</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="976">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>193</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>327</PDBx:auth_seq_id_2>
         <PDBx:dist>1.98</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="977">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>147</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="978">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>29</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="979">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>311</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>552</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="980">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>270</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>329</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="981">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>238</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>505</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="982">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>117</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="983">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>301</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="984">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>114</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>396</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="985">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>198</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>322</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="986">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>255</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="987">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>308</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>457</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="988">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="989">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>121</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="990">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="991">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>146</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="992">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>298</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>397</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="993">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="994">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>115</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="995">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="996">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>287</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>327</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="997">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>OXM</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>332</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>439</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="998">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>281</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="999">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>276</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>278</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1000">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>168</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1001">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>96</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1002">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1003">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1004">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>275</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>313</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1005">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1006">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>314</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1007">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>543</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1008">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>2.00</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1009">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>82</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>246</PDBx:auth_seq_id_2>
         <PDBx:dist>2.01</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1010">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>261</PDBx:auth_seq_id_2>
         <PDBx:dist>2.01</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1011">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>297</PDBx:auth_seq_id_2>
         <PDBx:dist>2.01</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1012">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>62</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>135</PDBx:auth_seq_id_2>
         <PDBx:dist>2.01</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1013">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>69</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>376</PDBx:auth_seq_id_2>
         <PDBx:dist>2.01</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1014">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>299</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1015">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>145</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1016">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>132</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1017">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>37</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>126</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1018">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>292</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1019">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>339</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>484</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1020">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>56</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1021">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>302</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1022">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>262</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>363</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1023">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OH</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>83</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>496</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1024">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>72</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>374</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1025">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>124</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1026">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>62</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>94</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1027">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NH2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>18</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>261</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1028">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>276</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>313</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1029">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>79</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>136</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1030">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1031">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>110</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1032">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>73</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>379</PDBx:auth_seq_id_2>
         <PDBx:dist>2.02</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1033">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>47</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>89</PDBx:auth_seq_id_2>
         <PDBx:dist>2.03</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1034">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>98</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>2.03</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1035">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>82</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>246</PDBx:auth_seq_id_2>
         <PDBx:dist>2.03</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1036">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>300</PDBx:auth_seq_id_2>
         <PDBx:dist>2.03</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1037">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>209</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>2.03</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1038">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>543</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>544</PDBx:auth_seq_id_2>
         <PDBx:dist>2.03</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1039">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>186</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>299</PDBx:auth_seq_id_2>
         <PDBx:dist>2.03</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1040">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>8</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>2.03</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>2_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1041">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>327</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>397</PDBx:auth_seq_id_2>
         <PDBx:dist>2.03</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1042">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>198</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>446</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1043">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>149</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>156</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1044">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>209</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>451</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1045">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>75</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>157</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1046">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>538</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1047">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>SG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>12</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>185</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1048">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>191</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1049">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>184</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1050">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>56</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>100</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1051">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>293</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>481</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1052">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>305</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>318</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1053">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>157</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>406</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1054">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>SG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>153</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1055">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>115</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>255</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1056">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>198</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>282</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1057">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>258</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1058">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>140</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>329</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1059">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>115</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1060">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>274</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1061">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>289</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1062">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C5B</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>58</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1063">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>95</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1064">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1065">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>111</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1066">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>38</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>123</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1067">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>407</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1068">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1069">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>281</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1070">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>78</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>93</PDBx:auth_seq_id_2>
         <PDBx:dist>2.05</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1071">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>104</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>237</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1072">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>127</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1073">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>12</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>178</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1074">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>85</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1075">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>313</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1076">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>228</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>432</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1077">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OH</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>236</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>426</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1078">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1079">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>29</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1080">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>122</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>258</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1081">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>363</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>368</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1082">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>53</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>53</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1083">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>175</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1084">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>151</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1085">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>112</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>248</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1086">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1087">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>301</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1088">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1089">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>18</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1090">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>283</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>286</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1091">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>275</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>302</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1092">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>303</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>323</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1093">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>12</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1094">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>299</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>327</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1095">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>193</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>328</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1096">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>292</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1097">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>147</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1098">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>302</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>317</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1099">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>143</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1100">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>59</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>95</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1101">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1102">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>37</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1103">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>158</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1104">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>8</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1105">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>139</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>173</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1106">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>544</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>545</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1107">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>250</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>530</PDBx:auth_seq_id_2>
         <PDBx:dist>2.07</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1108">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1109">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>66</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>71</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1110">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>115</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>266</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1111">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>64</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>121</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1112">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>285</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1113">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>111</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>291</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1114">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>56</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1115">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>135</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>382</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1116">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>531</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1117">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>193</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>328</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1118">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1119">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1120">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>479</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1121">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1122">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>22</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>22</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1123">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>174</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1124">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>184</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1125">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>SD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>26</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>33</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1126">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>78</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>92</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1127">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>49</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>91</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1128">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>115</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1129">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>25</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>49</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1130">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>30</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>81</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1131">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>302</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>319</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1132">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>5</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>546</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1133">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>24</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>49</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1134">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>206</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1135">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>149</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>287</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1136">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>127</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1137">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>282</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1138">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>142</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1139">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>65</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>124</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1140">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>48</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>92</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1141">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1142">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>104</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>237</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1143">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NH1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1144">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>266</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1145">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>24</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>49</PDBx:auth_seq_id_2>
         <PDBx:dist>2.09</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1146">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>82</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>246</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1147">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>258</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1148">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>293</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1149">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>112</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>248</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1150">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>154</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1151">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>206</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1152">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>281</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1153">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>323</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>415</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1154">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>183</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1155">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>311</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1156">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>142</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>171</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1157">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>173</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1158">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>79</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>95</PDBx:auth_seq_id_2>
         <PDBx:dist>2.10</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1159">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1160">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>281</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1161">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>66</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>407</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1162">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>115</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1163">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>149</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>271</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1164">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>475</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1165">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>324</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>475</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1166">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>37</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>128</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1167">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>144</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1168">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>120</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1169">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>491</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>491</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1170">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>127</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1171">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>96</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>241</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1172">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>263</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1173">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>2.11</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1174">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>207</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1175">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>191</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>283</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1176">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>66</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1177">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C5D</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>58</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1178">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>40</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>128</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1179">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>141</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>176</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1180">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>141</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>176</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1181">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>12</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>273</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1182">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>299</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>415</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1183">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>155</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>180</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1184">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1185">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>274</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1186">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>29</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1187">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>23</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>88</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1188">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1189">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>78</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>93</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1190">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1191">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>ND2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>38</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>123</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1192">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>301</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>2.12</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1193">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>175</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1194">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>74</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>130</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1195">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>190</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>322</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1196">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>111</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1197">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>299</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>415</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1198">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>198</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>321</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1199">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>11</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>179</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1200">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1201">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>294</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>481</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1202">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>177</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>273</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1203">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>144</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>172</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1204">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>31</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>80</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1205">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1206">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>139</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>173</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1207">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>78</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>93</PDBx:auth_seq_id_2>
         <PDBx:dist>2.13</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1208">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>281</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>312</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1209">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>123</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>529</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>13_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1210">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>12</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>178</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1211">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>127</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1212">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>360</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>360</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1213">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>11</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>273</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1214">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NZ</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>159</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1215">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>300</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1216">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>8</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>2_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1217">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>283</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>288</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1218">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PRO</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>154</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1219">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>293</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>481</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1220">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>1</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>310</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1221">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>112</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1222">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>209</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>301</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1223">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>181</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>400</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1224">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>17</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>296</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1225">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>76</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>157</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1226">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>84</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1227">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>PHE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>2</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>277</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1228">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>458</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>510</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1229">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1230">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>280</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>302</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1231">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>344</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1232">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>119</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>258</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1233">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OH</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C5A</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>244</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1234">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>135</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>382</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1235">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>61</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>96</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1236">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>36</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>87</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1237">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1238">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1239">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TRP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>148</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1240">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>275</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1241">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O4B</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>57</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1242">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>SG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>163</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>326</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1243">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>279</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>306</PDBx:auth_seq_id_2>
         <PDBx:dist>2.15</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1244">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>20</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>262</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1245">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>301</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>320</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1246">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>121</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1247">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1248">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>TYR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>145</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>475</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1249">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>139</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>398</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1250">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>64</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>121</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1251">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>286</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>511</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1252">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>34</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>84</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1253">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>78</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>93</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1254">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>280</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1255">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>39</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>87</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1256">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>283</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>288</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1257">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>6</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>311</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1258">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>30</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>52</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1259">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>168</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1260">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>251</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1261">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>168</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1262">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>302</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>15_445</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1263">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>274</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1264">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>145</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1265">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>108</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>169</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1266">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C5D</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>58</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1267">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>190</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>325</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1268">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>149</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>156</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1269">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>68</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>153</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1270">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>3</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>278</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1271">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>7</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>280</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>5_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1272">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>THR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>58</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>95</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1273">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CD</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1274">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>465</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>546</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1275">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>66</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>133</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1276">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LEU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>292</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1277">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>251</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>390</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1278">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ILE</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>77</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>133</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1279">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLY</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>279</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>553</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1280">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>259</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1281">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>262</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1282">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>49</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>93</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1283">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>MET</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>107</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>174</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1284">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>145</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1285">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>73</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>73</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1286">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>106</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>427</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1287">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>NE2</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>69</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>181</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>14_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1288">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ILE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>116</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1289">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>38</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>531</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1290">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>262</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>294</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1291">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>244</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1292">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>114</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1293">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>178</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>316</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>3_545</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1294">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>71</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>407</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1295">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OE1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLU</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>258</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1296">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>344</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1297">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ALA</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>36</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>534</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1298">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>181</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>400</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1299">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>14</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>182</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1300">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>MET</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TYR</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>33</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>83</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1301">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>106</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>431</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1302">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>C</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>28</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>51</PDBx:auth_seq_id_2>
         <PDBx:dist>2.18</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1303">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>118</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>11_655</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1304">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>SG</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>CYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>259</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>265</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1305">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O5D</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>NAD</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>330</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1306">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>OD1</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ASN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>16</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>115</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1307">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>106</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>356</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>4_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1308">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ3</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>TRP</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>127</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>247</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1309">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ALA</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>67</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>147</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1310">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ASP</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>130</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>339</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1311">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>55</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>99</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1312">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CA</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLY</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>13</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>175</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>7_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1313">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>70</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>520</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>8_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1314">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>CYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>SER</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>35</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>84</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1315">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CB</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>VAL</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>15</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>114</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_455</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1316">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>LYS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>81</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>242</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1317">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>CZ</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>THR</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>ARG</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>74</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>157</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>16_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1318">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>N</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PRO</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>GLN</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>289</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>324</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_565</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1319">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CB</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLN</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>111</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>335</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>6_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1320">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CE</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>4</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>10</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>12_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1321">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CA</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>153</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>400</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>9_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
      <PDBx:pdbx_validate_symm_contact id="1322">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>CD2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>C</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LEU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HIS</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>264</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>295</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
         <PDBx:site_symmetry_1>1_555</PDBx:site_symmetry_1>
         <PDBx:site_symmetry_2>10_555</PDBx:site_symmetry_2>
      </PDBx:pdbx_validate_symm_contact>
   </PDBx:pdbx_validate_symm_contactCategory>
   <PDBx:pdbx_validate_torsionCategory>
      <PDBx:pdbx_validate_torsion id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>14</PDBx:auth_seq_id>
         <PDBx:phi>178.75</PDBx:phi>
         <PDBx:psi>164.89</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>18</PDBx:auth_seq_id>
         <PDBx:phi>-174.28</PDBx:phi>
         <PDBx:psi>137.98</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>28</PDBx:auth_seq_id>
         <PDBx:phi>-107.67</PDBx:phi>
         <PDBx:psi>59.56</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>43</PDBx:auth_seq_id>
         <PDBx:phi>38.98</PDBx:phi>
         <PDBx:psi>58.32</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>73</PDBx:auth_seq_id>
         <PDBx:phi>-143.66</PDBx:phi>
         <PDBx:psi>37.15</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>83</PDBx:auth_seq_id>
         <PDBx:phi>-63.93</PDBx:phi>
         <PDBx:psi>11.00</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>155</PDBx:auth_seq_id>
         <PDBx:phi>-38.64</PDBx:phi>
         <PDBx:psi>-32.71</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>181</PDBx:auth_seq_id>
         <PDBx:phi>-39.06</PDBx:phi>
         <PDBx:psi>132.26</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>215</PDBx:auth_seq_id>
         <PDBx:phi>-103.54</PDBx:phi>
         <PDBx:psi>-61.67</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>219</PDBx:auth_seq_id>
         <PDBx:phi>-40.50</PDBx:phi>
         <PDBx:psi>-5.35</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>220</PDBx:auth_seq_id>
         <PDBx:phi>-145.55</PDBx:phi>
         <PDBx:psi>-81.87</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>222</PDBx:auth_seq_id>
         <PDBx:phi>119.68</PDBx:phi>
         <PDBx:psi>11.29</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="13">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>246</PDBx:auth_seq_id>
         <PDBx:phi>-137.13</PDBx:phi>
         <PDBx:psi>-62.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="14">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>276</PDBx:auth_seq_id>
         <PDBx:phi>92.54</PDBx:phi>
         <PDBx:psi>6.13</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="15">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>325</PDBx:auth_seq_id>
         <PDBx:phi>-26.77</PDBx:phi>
         <PDBx:psi>-63.27</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
   </PDBx:pdbx_validate_torsionCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="1LDM" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:details>SPACE GROUP C 4 21 2 (WHICH, MORE PROPERLY, SHOULD BE NAMED
 C 4 2 21) IS A NON-STANDARD REPRESENTATION OF SPACE GROUP
 P 4 21 2.  IN THIS CASE THE AXES OF THE UNIT CELL ARE
 CONSIDERED TO BE LEFT-HANDED.</PDBx:details>
         <PDBx:ls_R_factor_obs>0.1730000</PDBx:ls_R_factor_obs>
         <PDBx:ls_d_res_high>2.1</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>6.0</PDBx:ls_d_res_low>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="LAST" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>2.1</PDBx:d_res_high>
         <PDBx:d_res_low>6.0</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>245</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>2843</PDBx:number_atoms_total>
         <PDBx:pdbx_number_atoms_ligand>56</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>0</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>2542</PDBx:pdbx_number_atoms_protein>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_bond_d">
         <PDBx:dev_ideal>0.018</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.030</PDBx:dev_ideal_target>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_angle_d">
         <PDBx:dev_ideal>0.048</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.040</PDBx:dev_ideal_target>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_angle_deg">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_planar_d">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_hb_or_metal_coord">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_mcbond_it">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_mcangle_it">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_scbond_it">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_scangle_it">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_plane_restr">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_chiral_restr">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_singtor_nbd">
         <PDBx:dev_ideal>0.213</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.500</PDBx:dev_ideal_target>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_multtor_nbd">
         <PDBx:dev_ideal>0.267</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.500</PDBx:dev_ideal_target>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_xhyhbond_nbd">
         <PDBx:dev_ideal>0.260</PDBx:dev_ideal>
         <PDBx:dev_ideal_target>0.500</PDBx:dev_ideal_target>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_xyhbond_nbd">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_planar_tor">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_staggered_tor">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_orthonormal_tor">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_transverse_tor">
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="p_special_tor">
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>PROLSQ</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="1LDM">
         <PDBx:pdbx_descriptor>M4 LACTATE DEHYDROGENASE (E.C.1.1.1.27) TERNARY COMPLEX WITH NAD AND OXAMATE</PDBx:pdbx_descriptor>
         <PDBx:title>Refined crystal structure of dogfish M4 apo-lactate dehydrogenase</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="C">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="D">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="E">
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_biolCategory>
      <PDBx:struct_biol id="1">
         <PDBx:details>NON-CRYSTALLOGRAPHIC SYMMETRY ELEMENTS CORRESPONDING TO THE
THREE ORTHOGONAL MOLECULAR SYMMETRY AXES ARE PRESENTED ON
THE *MTRIX* RECORDS BELOW.</PDBx:details>
      </PDBx:struct_biol>
   </PDBx:struct_biolCategory>
   <PDBx:struct_confCategory>
      <PDBx:struct_conf id="HELX_P1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>2</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>2</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>8</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>8</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>7</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLY</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>29</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLY</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>29</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>43</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>43</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>15</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>MET</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>54</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>MET</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>54</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>69</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>69</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AC</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>16</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P4">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLY</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>103</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLY</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>103</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:details>3/10 HELIX 103-111</PDBx:details>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>121</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>121</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AD</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>19</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P5">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PHE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>119</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PHE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>119</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:details>CONTIGUOUS WITH HELIX AD</PDBx:details>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>128</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>128</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AE</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>10</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P6">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>VAL</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>140</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>VAL</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>140</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:details>SHORTER IN APO</PDBx:details>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>152</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>152</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>A1F</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>13</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P7">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>CYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>163</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>CYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>163</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:details>3 H BONDS IN MIDDL ABSENT APO</PDBx:details>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>179</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>179</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>A2F</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>17</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P8">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>TRP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>224</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>TRP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>224</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:details>3/10 H-BOND 234-237</PDBx:details>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>TYR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>236</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>TYR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>236</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>A1G</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>13</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P9">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>VAL</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>238</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>VAL</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>238</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>243</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>243</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>A2G</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P10">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ALA</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>248</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ALA</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>248</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:details>3/10 H-BOND 248-251</PDBx:details>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>263</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>263</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>A3G</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>16</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P11">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>PRO</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>307</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>PRO</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>307</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>323</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>323</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AH</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>17</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
   </PDBx:struct_confCategory>
   <PDBx:struct_conf_typeCategory>
      <PDBx:struct_conf_type id="HELX_P">
      </PDBx:struct_conf_type>
   </PDBx:struct_conf_typeCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="1LDM">
         <PDBx:pdbx_keywords>OXIDOREDUCTASE</PDBx:pdbx_keywords>
         <PDBx:text>OXIDOREDUCTASE</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_mon_prot_cisCategory>
      <PDBx:struct_mon_prot_cis pdbx_id="1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>138</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>138</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>A</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>139</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>A</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>139</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-2.95</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
   </PDBx:struct_mon_prot_cisCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:db_code>LDHA_SQUAC</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>1</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>P00341</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>ATLKDKLIGHLATSQEPRSYNKITVVGVGAVGMACAISILMKDLADEVALVDVMEDKLKGEMMDLQHGSLFLHTAKIVSG
KDYSVSAGSKLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKHSPDCIILVVSNPVDVLTYVAWKLSGLPMHRIIG
SGCNLDSARFRYLMGERLGVHSCSCHGWVIGEHGDSVPSVWSGMWNALKELHPELGTNKDKQDWKKLHKDVVDSAYEVIK
LKGYTSWAIGLSVADLAETIMKNLCRVHPVSTMVKDFYGIKDNVFLSLPCVLNDHGISNIVKMKLKPDEEQQLQKSATTL
WDIQKDLKF</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>1</PDBx:db_align_beg>
         <PDBx:db_align_end>329</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>1LDM</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>1</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>329</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>P00341</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>1</PDBx:seq_align_beg>
         <PDBx:seq_align_end>329</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_ref_seq_difCategory>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="1">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>TRP</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>ASN</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>205</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>1LDM</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P00341</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>205</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>205</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="2">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>ASN</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>VAL</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>206</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>1LDM</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P00341</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>206</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>206</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="3">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>LEU</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>SER</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>208</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>1LDM</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P00341</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>208</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>208</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="4">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>LYS</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>ILE</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>209</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>1LDM</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P00341</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>209</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>209</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="5">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>GLU</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>LYS</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>210</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>1LDM</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P00341</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>210</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>210</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="6">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>GLU</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>LEU</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>214</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>1LDM</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P00341</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>214</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>214</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="7">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>LEU</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>ASP</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>215</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>1LDM</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P00341</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>215</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>215</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="8">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>ASP</PDBx:db_mon_id>
         <PDBx:details>CONFLICT</PDBx:details>
         <PDBx:mon_id>ASN</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>308</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>1LDM</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P00341</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>308</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>308</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
   </PDBx:struct_ref_seq_difCategory>
   <PDBx:struct_sheetCategory>
      <PDBx:struct_sheet id="SH1">
         <PDBx:number_strands>6</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="SH2">
         <PDBx:number_strands>3</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="SH3">
         <PDBx:number_strands>3</PDBx:number_strands>
      </PDBx:struct_sheet>
   </PDBx:struct_sheetCategory>
   <PDBx:struct_sheet_orderCategory>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="SH1">
         <PDBx:sense>parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="SH1">
         <PDBx:sense>parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="3" range_id_2="4" sheet_id="SH1">
         <PDBx:sense>parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="4" range_id_2="5" sheet_id="SH1">
         <PDBx:sense>parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="5" range_id_2="6" sheet_id="SH1">
         <PDBx:sense>parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="SH2">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="SH2">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="SH3">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="2" range_id_2="3" sheet_id="SH3">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
   </PDBx:struct_sheet_orderCategory>
   <PDBx:struct_sheet_rangeCategory>
      <PDBx:struct_sheet_range id="1" sheet_id="SH1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>76</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>76</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>80</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>80</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="SH1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>47</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>47</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>51</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>51</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="SH1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>21</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>21</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>26</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>26</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="4" sheet_id="SH1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LYS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>90</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LYS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>90</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ILE</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>94</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ILE</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>94</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="5" sheet_id="SH1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>132</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>132</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>136</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>136</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="6" sheet_id="SH1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ARG</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>157</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ARG</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>157</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLY</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>160</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLY</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>160</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="SH2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>184</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>184</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>TRP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>188</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>TRP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>188</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="SH2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLY</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>203</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLY</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>203</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>206</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>206</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="SH2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>209</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>209</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>211</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>211</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="SH3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LEU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>264</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LEU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>264</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>MET</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>273</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>MET</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>273</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="SH3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>283</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>283</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>293</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>293</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="3" sheet_id="SH3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>HIS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>295</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>HIS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>295</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>VAL</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>301</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>VAL</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>301</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
   </PDBx:struct_sheet_rangeCategory>
   <PDBx:struct_siteCategory>
      <PDBx:struct_site id="AC1">
         <PDBx:details>BINDING SITE FOR RESIDUE NAD A 330</PDBx:details>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>41</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC2">
         <PDBx:details>BINDING SITE FOR RESIDUE OXM A 331</PDBx:details>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>4</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC3">
         <PDBx:details>BINDING SITE FOR RESIDUE OXM A 332</PDBx:details>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>7</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
   </PDBx:struct_siteCategory>
   <PDBx:struct_site_genCategory>
      <PDBx:struct_site_gen id="1" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>28</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_seq_id>28</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>16_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="2" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>29</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>29</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>16_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="3" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>52</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>52</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="4" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>53</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_seq_id>53</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>13_655</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="5" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>53</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_seq_id>53</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="6" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>54</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>54</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>16_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="7" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>54</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>54</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="8" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>55</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>55</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>16_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="9" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>56</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>56</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>16_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="10" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>57</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>57</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>16_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="11" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>58</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>58</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>16_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="12" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>59</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>59</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>16_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="13" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>60</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>60</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>16_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="14" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>61</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>61</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>16_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="15" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>79</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>79</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>16_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="16" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>81</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>81</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>13_655</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="17" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>82</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASP</PDBx:label_comp_id>
         <PDBx:label_seq_id>82</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>13_655</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="18" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>83</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>83</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>13_655</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="19" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>83</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>83</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="20" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>95</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_seq_id>95</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="21" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>96</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>96</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="22" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>98</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>98</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="23" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>99</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>99</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="24" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>136</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_seq_id>136</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="25" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>137</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>137</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="26" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>138</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>138</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="27" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>161</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>161</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="28" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>193</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>193</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="29" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>241</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>241</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>4_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="30" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>242</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>242</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>4_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="31" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>244</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>244</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>4_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="32" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>246</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>246</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>4_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="33" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>OXM</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>331</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>OXM</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="34" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>347</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>13_655</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="35" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>353</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="36" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>359</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>4_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="37" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>373</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="38" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>384</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>16_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="39" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>493</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="40" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>496</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>4_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="41" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>497</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>41</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="42" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>106</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>106</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>4</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="43" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>193</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>193</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>4</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="44" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>235</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>235</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>4</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="45" site_id="AC2">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>NAD</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>330</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>NAD</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>4</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="46" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>111</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLN</PDBx:label_comp_id>
         <PDBx:label_seq_id>111</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>3_545</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="47" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>171</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>171</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="48" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>186</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>186</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="49" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>291</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_seq_id>291</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>10_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="50" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>335</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>7_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="51" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>424</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>10_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="52" site_id="AC3">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>439</PDBx:auth_seq_id>
         <PDBx:label_asym_id>E</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>7</PDBx:pdbx_num_res>
         <PDBx:symmetry>3_545</PDBx:symmetry>
      </PDBx:struct_site_gen>
   </PDBx:struct_site_genCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="1LDM">
         <PDBx:Int_Tables_number>90</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>C 4 21 2</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
