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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
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         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>N</PDBx:label_atom_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:label_atom_id>CA</PDBx:label_atom_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_seq_id>478</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_seq_id>327</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
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         <PDBx:auth_atom_id>O</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>327</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>CB</PDBx:auth_atom_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>327</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>327</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
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         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
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         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>328</PDBx:auth_seq_id>
         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
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         <PDBx:group_PDB>ATOM</PDBx:group_PDB>
         <PDBx:label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>308</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>308</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>308</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>308</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.1350</PDBx:U23>
         <PDBx:U33>0.6209</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.1227</PDBx:U23>
         <PDBx:U33>0.5939</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.1319</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.6939</PDBx:U22>
         <PDBx:U23>-0.1399</PDBx:U23>
         <PDBx:U33>0.6370</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.7179</PDBx:U22>
         <PDBx:U23>-0.1535</PDBx:U23>
         <PDBx:U33>0.6851</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.1267</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.1426</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U12>-0.3051</PDBx:U12>
         <PDBx:U13>-0.0829</PDBx:U13>
         <PDBx:U22>0.6685</PDBx:U22>
         <PDBx:U23>-0.1426</PDBx:U23>
         <PDBx:U33>0.6189</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.1353</PDBx:U23>
         <PDBx:U33>0.6153</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="36">
         <PDBx:U11>0.6854</PDBx:U11>
         <PDBx:U12>-0.3108</PDBx:U12>
         <PDBx:U13>-0.0898</PDBx:U13>
         <PDBx:U22>0.6764</PDBx:U22>
         <PDBx:U23>-0.1349</PDBx:U23>
         <PDBx:U33>0.6117</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="37">
         <PDBx:U11>0.6429</PDBx:U11>
         <PDBx:U12>-0.2947</PDBx:U12>
         <PDBx:U13>-0.0788</PDBx:U13>
         <PDBx:U22>0.6510</PDBx:U22>
         <PDBx:U23>-0.1204</PDBx:U23>
         <PDBx:U33>0.5563</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="38">
         <PDBx:U11>0.6424</PDBx:U11>
         <PDBx:U12>-0.2946</PDBx:U12>
         <PDBx:U13>-0.0780</PDBx:U13>
         <PDBx:U22>0.6498</PDBx:U22>
         <PDBx:U23>-0.1198</PDBx:U23>
         <PDBx:U33>0.5563</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="39">
         <PDBx:U11>0.6217</PDBx:U11>
         <PDBx:U12>-0.2810</PDBx:U12>
         <PDBx:U13>-0.0683</PDBx:U13>
         <PDBx:U22>0.6136</PDBx:U22>
         <PDBx:U23>-0.1187</PDBx:U23>
         <PDBx:U33>0.5096</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="40">
         <PDBx:U11>0.6175</PDBx:U11>
         <PDBx:U12>-0.2810</PDBx:U12>
         <PDBx:U13>-0.0667</PDBx:U13>
         <PDBx:U22>0.6079</PDBx:U22>
         <PDBx:U23>-0.1174</PDBx:U23>
         <PDBx:U33>0.5065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="41">
         <PDBx:U11>0.7357</PDBx:U11>
         <PDBx:U12>-0.3194</PDBx:U12>
         <PDBx:U13>-0.1121</PDBx:U13>
         <PDBx:U22>0.7459</PDBx:U22>
         <PDBx:U23>-0.1506</PDBx:U23>
         <PDBx:U33>0.6660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="42">
         <PDBx:U11>0.7307</PDBx:U11>
         <PDBx:U12>-0.3192</PDBx:U12>
         <PDBx:U13>-0.1115</PDBx:U13>
         <PDBx:U22>0.7423</PDBx:U22>
         <PDBx:U23>-0.1495</PDBx:U23>
         <PDBx:U33>0.6617</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="43">
         <PDBx:U11>0.7787</PDBx:U11>
         <PDBx:U12>-0.3346</PDBx:U12>
         <PDBx:U13>-0.1241</PDBx:U13>
         <PDBx:U22>0.7692</PDBx:U22>
         <PDBx:U23>-0.1668</PDBx:U23>
         <PDBx:U33>0.7200</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="44">
         <PDBx:U11>0.7209</PDBx:U11>
         <PDBx:U12>-0.3051</PDBx:U12>
         <PDBx:U13>-0.1137</PDBx:U13>
         <PDBx:U22>0.7301</PDBx:U22>
         <PDBx:U23>-0.1559</PDBx:U23>
         <PDBx:U33>0.6211</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="45">
         <PDBx:U11>0.7303</PDBx:U11>
         <PDBx:U12>-0.3258</PDBx:U12>
         <PDBx:U13>-0.1199</PDBx:U13>
         <PDBx:U22>0.7841</PDBx:U22>
         <PDBx:U23>-0.1424</PDBx:U23>
         <PDBx:U33>0.6862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="46">
         <PDBx:U11>0.7778</PDBx:U11>
         <PDBx:U12>-0.3360</PDBx:U12>
         <PDBx:U13>-0.1253</PDBx:U13>
         <PDBx:U22>0.7709</PDBx:U22>
         <PDBx:U23>-0.1670</PDBx:U23>
         <PDBx:U33>0.7217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="47">
         <PDBx:U11>0.6264</PDBx:U11>
         <PDBx:U12>-0.2966</PDBx:U12>
         <PDBx:U13>-0.0808</PDBx:U13>
         <PDBx:U22>0.6673</PDBx:U22>
         <PDBx:U23>-0.1095</PDBx:U23>
         <PDBx:U33>0.5591</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="48">
         <PDBx:U11>0.6217</PDBx:U11>
         <PDBx:U12>-0.2820</PDBx:U12>
         <PDBx:U13>-0.0715</PDBx:U13>
         <PDBx:U22>0.6781</PDBx:U22>
         <PDBx:U23>-0.0958</PDBx:U23>
         <PDBx:U33>0.5442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="49">
         <PDBx:U11>0.6160</PDBx:U11>
         <PDBx:U12>-0.2714</PDBx:U12>
         <PDBx:U13>-0.0740</PDBx:U13>
         <PDBx:U22>0.6723</PDBx:U22>
         <PDBx:U23>-0.1014</PDBx:U23>
         <PDBx:U33>0.5120</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="50">
         <PDBx:U11>0.5860</PDBx:U11>
         <PDBx:U12>-0.2582</PDBx:U12>
         <PDBx:U13>-0.0616</PDBx:U13>
         <PDBx:U22>0.6322</PDBx:U22>
         <PDBx:U23>-0.0942</PDBx:U23>
         <PDBx:U33>0.4639</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="51">
         <PDBx:U11>0.6533</PDBx:U11>
         <PDBx:U12>-0.2861</PDBx:U12>
         <PDBx:U13>-0.0772</PDBx:U13>
         <PDBx:U22>0.7486</PDBx:U22>
         <PDBx:U23>-0.0855</PDBx:U23>
         <PDBx:U33>0.6004</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="52">
         <PDBx:U11>0.6448</PDBx:U11>
         <PDBx:U12>-0.2771</PDBx:U12>
         <PDBx:U13>-0.0907</PDBx:U13>
         <PDBx:U22>0.7127</PDBx:U22>
         <PDBx:U23>-0.1145</PDBx:U23>
         <PDBx:U33>0.5395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="53">
         <PDBx:U11>0.6198</PDBx:U11>
         <PDBx:U12>-0.2659</PDBx:U12>
         <PDBx:U13>-0.0951</PDBx:U13>
         <PDBx:U22>0.6889</PDBx:U22>
         <PDBx:U23>-0.1208</PDBx:U23>
         <PDBx:U33>0.4894</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="54">
         <PDBx:U11>0.6391</PDBx:U11>
         <PDBx:U12>-0.2584</PDBx:U12>
         <PDBx:U13>-0.0863</PDBx:U13>
         <PDBx:U22>0.6727</PDBx:U22>
         <PDBx:U23>-0.1268</PDBx:U23>
         <PDBx:U33>0.4852</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="55">
         <PDBx:U11>0.6207</PDBx:U11>
         <PDBx:U12>-0.2453</PDBx:U12>
         <PDBx:U13>-0.0788</PDBx:U13>
         <PDBx:U22>0.6499</PDBx:U22>
         <PDBx:U23>-0.1227</PDBx:U23>
         <PDBx:U33>0.4474</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="56">
         <PDBx:U11>0.6718</PDBx:U11>
         <PDBx:U12>-0.2723</PDBx:U12>
         <PDBx:U13>-0.1172</PDBx:U13>
         <PDBx:U22>0.7616</PDBx:U22>
         <PDBx:U23>-0.1357</PDBx:U23>
         <PDBx:U33>0.5438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="57">
         <PDBx:U11>0.7091</PDBx:U11>
         <PDBx:U12>-0.2790</PDBx:U12>
         <PDBx:U13>-0.1240</PDBx:U13>
         <PDBx:U22>0.8446</PDBx:U22>
         <PDBx:U23>-0.1276</PDBx:U23>
         <PDBx:U33>0.5929</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="58">
         <PDBx:U11>0.7212</PDBx:U11>
         <PDBx:U12>-0.2716</PDBx:U12>
         <PDBx:U13>-0.1131</PDBx:U13>
         <PDBx:U22>0.8719</PDBx:U22>
         <PDBx:U23>-0.1122</PDBx:U23>
         <PDBx:U33>0.5985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="59">
         <PDBx:U11>0.7960</PDBx:U11>
         <PDBx:U12>-0.2913</PDBx:U12>
         <PDBx:U13>-0.1409</PDBx:U13>
         <PDBx:U22>0.9537</PDBx:U22>
         <PDBx:U23>-0.1367</PDBx:U23>
         <PDBx:U33>0.6962</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="60">
         <PDBx:U11>0.5907</PDBx:U11>
         <PDBx:U12>-0.2667</PDBx:U12>
         <PDBx:U13>-0.0873</PDBx:U13>
         <PDBx:U22>0.5998</PDBx:U22>
         <PDBx:U23>-0.1360</PDBx:U23>
         <PDBx:U33>0.4397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="61">
         <PDBx:U11>0.6271</PDBx:U11>
         <PDBx:U12>-0.2593</PDBx:U12>
         <PDBx:U13>-0.0791</PDBx:U13>
         <PDBx:U22>0.6039</PDBx:U22>
         <PDBx:U23>-0.1415</PDBx:U23>
         <PDBx:U33>0.4545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="62">
         <PDBx:U11>0.5890</PDBx:U11>
         <PDBx:U12>-0.2490</PDBx:U12>
         <PDBx:U13>-0.0577</PDBx:U13>
         <PDBx:U22>0.5553</PDBx:U22>
         <PDBx:U23>-0.1256</PDBx:U23>
         <PDBx:U33>0.4099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="63">
         <PDBx:U11>0.5566</PDBx:U11>
         <PDBx:U12>-0.2383</PDBx:U12>
         <PDBx:U13>-0.0495</PDBx:U13>
         <PDBx:U22>0.5094</PDBx:U22>
         <PDBx:U23>-0.1249</PDBx:U23>
         <PDBx:U33>0.3583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="64">
         <PDBx:U11>0.6365</PDBx:U11>
         <PDBx:U12>-0.2704</PDBx:U12>
         <PDBx:U13>-0.0846</PDBx:U13>
         <PDBx:U22>0.5887</PDBx:U22>
         <PDBx:U23>-0.1538</PDBx:U23>
         <PDBx:U33>0.4694</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="65">
         <PDBx:U11>0.7255</PDBx:U11>
         <PDBx:U12>-0.2791</PDBx:U12>
         <PDBx:U13>-0.1073</PDBx:U13>
         <PDBx:U22>0.6811</PDBx:U22>
         <PDBx:U23>-0.1739</PDBx:U23>
         <PDBx:U33>0.5600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="66">
         <PDBx:U11>0.8181</PDBx:U11>
         <PDBx:U12>-0.2927</PDBx:U12>
         <PDBx:U13>-0.1134</PDBx:U13>
         <PDBx:U22>0.7486</PDBx:U22>
         <PDBx:U23>-0.1860</PDBx:U23>
         <PDBx:U33>0.6631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="67">
         <PDBx:U11>0.7107</PDBx:U11>
         <PDBx:U12>-0.2978</PDBx:U12>
         <PDBx:U13>-0.1014</PDBx:U13>
         <PDBx:U22>0.6272</PDBx:U22>
         <PDBx:U23>-0.1772</PDBx:U23>
         <PDBx:U33>0.5674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="68">
         <PDBx:U11>0.8905</PDBx:U11>
         <PDBx:U12>-0.2977</PDBx:U12>
         <PDBx:U13>-0.1328</PDBx:U13>
         <PDBx:U22>0.8141</PDBx:U22>
         <PDBx:U23>-0.2071</PDBx:U23>
         <PDBx:U33>0.7305</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="69">
         <PDBx:U11>0.5372</PDBx:U11>
         <PDBx:U12>-0.2519</PDBx:U12>
         <PDBx:U13>-0.0498</PDBx:U13>
         <PDBx:U22>0.5113</PDBx:U22>
         <PDBx:U23>-0.1134</PDBx:U23>
         <PDBx:U33>0.3751</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="70">
         <PDBx:U11>0.5791</PDBx:U11>
         <PDBx:U12>-0.2413</PDBx:U12>
         <PDBx:U13>-0.0316</PDBx:U13>
         <PDBx:U22>0.5462</PDBx:U22>
         <PDBx:U23>-0.0997</PDBx:U23>
         <PDBx:U33>0.4120</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="71">
         <PDBx:U11>0.5960</PDBx:U11>
         <PDBx:U12>-0.2307</PDBx:U12>
         <PDBx:U13>-0.0274</PDBx:U13>
         <PDBx:U22>0.5759</PDBx:U22>
         <PDBx:U23>-0.0921</PDBx:U23>
         <PDBx:U33>0.4190</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="72">
         <PDBx:U11>0.5176</PDBx:U11>
         <PDBx:U12>-0.2214</PDBx:U12>
         <PDBx:U13>-0.0154</PDBx:U13>
         <PDBx:U22>0.4849</PDBx:U22>
         <PDBx:U23>-0.0874</PDBx:U23>
         <PDBx:U33>0.3280</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="73">
         <PDBx:U11>0.5414</PDBx:U11>
         <PDBx:U12>-0.2446</PDBx:U12>
         <PDBx:U13>-0.0275</PDBx:U13>
         <PDBx:U22>0.5177</PDBx:U22>
         <PDBx:U23>-0.0900</PDBx:U23>
         <PDBx:U33>0.3945</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="74">
         <PDBx:U11>0.5544</PDBx:U11>
         <PDBx:U12>-0.2320</PDBx:U12>
         <PDBx:U13>-0.0113</PDBx:U13>
         <PDBx:U22>0.5263</PDBx:U22>
         <PDBx:U23>-0.0779</PDBx:U23>
         <PDBx:U33>0.4025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="75">
         <PDBx:U11>0.8321</PDBx:U11>
         <PDBx:U12>-0.2247</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.7724</PDBx:U22>
         <PDBx:U23>-0.0804</PDBx:U23>
         <PDBx:U33>0.6635</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="76">
         <PDBx:U11>0.7573</PDBx:U11>
         <PDBx:U12>-0.2367</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.6835</PDBx:U22>
         <PDBx:U23>-0.0877</PDBx:U23>
         <PDBx:U33>0.6026</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="77">
         <PDBx:U11>0.4744</PDBx:U11>
         <PDBx:U12>-0.2326</PDBx:U12>
         <PDBx:U13>-0.0376</PDBx:U13>
         <PDBx:U22>0.4803</PDBx:U22>
         <PDBx:U23>-0.0907</PDBx:U23>
         <PDBx:U33>0.3047</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="78">
         <PDBx:U11>0.5467</PDBx:U11>
         <PDBx:U12>-0.2228</PDBx:U12>
         <PDBx:U13>-0.0353</PDBx:U13>
         <PDBx:U22>0.5649</PDBx:U22>
         <PDBx:U23>-0.0838</PDBx:U23>
         <PDBx:U33>0.3683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="79">
         <PDBx:U11>0.5698</PDBx:U11>
         <PDBx:U12>-0.2160</PDBx:U12>
         <PDBx:U13>-0.0361</PDBx:U13>
         <PDBx:U22>0.5762</PDBx:U22>
         <PDBx:U23>-0.0912</PDBx:U23>
         <PDBx:U33>0.3711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="80">
         <PDBx:U11>0.4973</PDBx:U11>
         <PDBx:U12>-0.2073</PDBx:U12>
         <PDBx:U13>-0.0255</PDBx:U13>
         <PDBx:U22>0.4955</PDBx:U22>
         <PDBx:U23>-0.0843</PDBx:U23>
         <PDBx:U33>0.2896</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="81">
         <PDBx:U11>0.5771</PDBx:U11>
         <PDBx:U12>-0.2270</PDBx:U12>
         <PDBx:U13>-0.0479</PDBx:U13>
         <PDBx:U22>0.6284</PDBx:U22>
         <PDBx:U23>-0.0824</PDBx:U23>
         <PDBx:U33>0.4065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="82">
         <PDBx:U11>0.5840</PDBx:U11>
         <PDBx:U12>-0.2194</PDBx:U12>
         <PDBx:U13>-0.0450</PDBx:U13>
         <PDBx:U22>0.6470</PDBx:U22>
         <PDBx:U23>-0.0757</PDBx:U23>
         <PDBx:U33>0.3980</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="83">
         <PDBx:U11>0.5632</PDBx:U11>
         <PDBx:U12>-0.2344</PDBx:U12>
         <PDBx:U13>-0.0465</PDBx:U13>
         <PDBx:U22>0.6306</PDBx:U22>
         <PDBx:U23>-0.0732</PDBx:U23>
         <PDBx:U33>0.4121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="84">
         <PDBx:U11>0.5855</PDBx:U11>
         <PDBx:U12>-0.2198</PDBx:U12>
         <PDBx:U13>-0.0499</PDBx:U13>
         <PDBx:U22>0.5910</PDBx:U22>
         <PDBx:U23>-0.1058</PDBx:U23>
         <PDBx:U33>0.3804</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="101">
         <PDBx:U11>0.5385</PDBx:U11>
         <PDBx:U12>-0.1996</PDBx:U12>
         <PDBx:U13>0.0170</PDBx:U13>
         <PDBx:U22>0.5093</PDBx:U22>
         <PDBx:U23>-0.0563</PDBx:U23>
         <PDBx:U33>0.3558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="102">
         <PDBx:U11>0.5355</PDBx:U11>
         <PDBx:U12>-0.1940</PDBx:U12>
         <PDBx:U13>0.0324</PDBx:U13>
         <PDBx:U22>0.4745</PDBx:U22>
         <PDBx:U23>-0.0607</PDBx:U23>
         <PDBx:U33>0.3345</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="103">
         <PDBx:U11>0.5352</PDBx:U11>
         <PDBx:U12>-0.1918</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.5060</PDBx:U22>
         <PDBx:U23>-0.0735</PDBx:U23>
         <PDBx:U33>0.3101</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="104">
         <PDBx:U11>0.5638</PDBx:U11>
         <PDBx:U12>-0.1838</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.5412</PDBx:U22>
         <PDBx:U23>-0.0724</PDBx:U23>
         <PDBx:U33>0.3282</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="105">
         <PDBx:U11>0.5897</PDBx:U11>
         <PDBx:U12>-0.1778</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.5529</PDBx:U22>
         <PDBx:U23>-0.0784</PDBx:U23>
         <PDBx:U33>0.3381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="106">
         <PDBx:U11>0.5158</PDBx:U11>
         <PDBx:U12>-0.1708</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.4755</PDBx:U22>
         <PDBx:U23>-0.0733</PDBx:U23>
         <PDBx:U33>0.2582</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="107">
         <PDBx:U11>0.5841</PDBx:U11>
         <PDBx:U12>-0.1819</PDBx:U12>
         <PDBx:U13>-0.0206</PDBx:U13>
         <PDBx:U22>0.5829</PDBx:U22>
         <PDBx:U23>-0.0782</PDBx:U23>
         <PDBx:U33>0.3428</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="108">
         <PDBx:U11>0.5099</PDBx:U11>
         <PDBx:U12>-0.1889</PDBx:U12>
         <PDBx:U13>-0.0234</PDBx:U13>
         <PDBx:U22>0.5298</PDBx:U22>
         <PDBx:U23>-0.0709</PDBx:U23>
         <PDBx:U33>0.2798</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="109">
         <PDBx:U11>0.5308</PDBx:U11>
         <PDBx:U12>-0.1902</PDBx:U12>
         <PDBx:U13>-0.0395</PDBx:U13>
         <PDBx:U22>0.5761</PDBx:U22>
         <PDBx:U23>-0.0777</PDBx:U23>
         <PDBx:U33>0.2921</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="110">
         <PDBx:U11>0.5188</PDBx:U11>
         <PDBx:U12>-0.1854</PDBx:U12>
         <PDBx:U13>-0.0138</PDBx:U13>
         <PDBx:U22>0.5391</PDBx:U22>
         <PDBx:U23>-0.0582</PDBx:U23>
         <PDBx:U33>0.2893</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="111">
         <PDBx:U11>0.5853</PDBx:U11>
         <PDBx:U12>-0.1799</PDBx:U12>
         <PDBx:U13>-0.0082</PDBx:U13>
         <PDBx:U22>0.5398</PDBx:U22>
         <PDBx:U23>-0.0897</PDBx:U23>
         <PDBx:U33>0.3263</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="112">
         <PDBx:U11>0.6323</PDBx:U11>
         <PDBx:U12>-0.1723</PDBx:U12>
         <PDBx:U13>-0.0080</PDBx:U13>
         <PDBx:U22>0.5740</PDBx:U22>
         <PDBx:U23>-0.0971</PDBx:U23>
         <PDBx:U33>0.3555</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="113">
         <PDBx:U11>0.6625</PDBx:U11>
         <PDBx:U12>-0.1717</PDBx:U12>
         <PDBx:U13>0.0076</PDBx:U13>
         <PDBx:U22>0.5894</PDBx:U22>
         <PDBx:U23>-0.0890</PDBx:U23>
         <PDBx:U33>0.3909</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="114">
         <PDBx:U11>0.6669</PDBx:U11>
         <PDBx:U12>-0.1635</PDBx:U12>
         <PDBx:U13>0.0108</PDBx:U13>
         <PDBx:U22>0.5881</PDBx:U22>
         <PDBx:U23>-0.0899</PDBx:U23>
         <PDBx:U33>0.3834</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="115">
         <PDBx:U11>0.7661</PDBx:U11>
         <PDBx:U12>-0.1749</PDBx:U12>
         <PDBx:U13>-0.0188</PDBx:U13>
         <PDBx:U22>0.6993</PDBx:U22>
         <PDBx:U23>-0.1124</PDBx:U23>
         <PDBx:U33>0.4808</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="116">
         <PDBx:U11>0.9115</PDBx:U11>
         <PDBx:U12>-0.1631</PDBx:U12>
         <PDBx:U13>-0.0233</PDBx:U13>
         <PDBx:U22>0.8357</PDBx:U22>
         <PDBx:U23>-0.1230</PDBx:U23>
         <PDBx:U33>0.6021</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="117">
         <PDBx:U11>0.9117</PDBx:U11>
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         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="150">
         <PDBx:U11>0.6258</PDBx:U11>
         <PDBx:U12>-0.1305</PDBx:U12>
         <PDBx:U13>0.0878</PDBx:U13>
         <PDBx:U22>0.5261</PDBx:U22>
         <PDBx:U23>-0.0063</PDBx:U23>
         <PDBx:U33>0.3506</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="151">
         <PDBx:U11>0.7081</PDBx:U11>
         <PDBx:U12>-0.1372</PDBx:U12>
         <PDBx:U13>0.0711</PDBx:U13>
         <PDBx:U22>0.6032</PDBx:U22>
         <PDBx:U23>-0.0112</PDBx:U23>
         <PDBx:U33>0.4377</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="152">
         <PDBx:U11>0.7210</PDBx:U11>
         <PDBx:U12>-0.1397</PDBx:U12>
         <PDBx:U13>0.0606</PDBx:U13>
         <PDBx:U22>0.6233</PDBx:U22>
         <PDBx:U23>-0.0151</PDBx:U23>
         <PDBx:U33>0.4521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="153">
         <PDBx:U11>0.7083</PDBx:U11>
         <PDBx:U12>-0.1377</PDBx:U12>
         <PDBx:U13>0.0777</PDBx:U13>
         <PDBx:U22>0.5890</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.4450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="154">
         <PDBx:U11>0.7290</PDBx:U11>
         <PDBx:U12>-0.1514</PDBx:U12>
         <PDBx:U13>0.0553</PDBx:U13>
         <PDBx:U22>0.6220</PDBx:U22>
         <PDBx:U23>-0.0247</PDBx:U23>
         <PDBx:U33>0.4813</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="155">
         <PDBx:U11>0.5430</PDBx:U11>
         <PDBx:U12>-0.1483</PDBx:U12>
         <PDBx:U13>0.0820</PDBx:U13>
         <PDBx:U22>0.4242</PDBx:U22>
         <PDBx:U23>-0.0262</PDBx:U23>
         <PDBx:U33>0.2981</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="156">
         <PDBx:U11>0.5555</PDBx:U11>
         <PDBx:U12>-0.1459</PDBx:U12>
         <PDBx:U13>0.0921</PDBx:U13>
         <PDBx:U22>0.4394</PDBx:U22>
         <PDBx:U23>-0.0214</PDBx:U23>
         <PDBx:U33>0.3128</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="157">
         <PDBx:U11>0.4781</PDBx:U11>
         <PDBx:U12>-0.1439</PDBx:U12>
         <PDBx:U13>0.1013</PDBx:U13>
         <PDBx:U22>0.3568</PDBx:U22>
         <PDBx:U23>-0.0084</PDBx:U23>
         <PDBx:U33>0.2380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="158">
         <PDBx:U11>0.5298</PDBx:U11>
         <PDBx:U12>-0.1455</PDBx:U12>
         <PDBx:U13>0.0986</PDBx:U13>
         <PDBx:U22>0.3980</PDBx:U22>
         <PDBx:U23>-0.0085</PDBx:U23>
         <PDBx:U33>0.2928</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="159">
         <PDBx:U11>0.5119</PDBx:U11>
         <PDBx:U12>-0.1538</PDBx:U12>
         <PDBx:U13>0.0898</PDBx:U13>
         <PDBx:U22>0.3909</PDBx:U22>
         <PDBx:U23>-0.0361</PDBx:U23>
         <PDBx:U33>0.2828</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="160">
         <PDBx:U11>0.4974</PDBx:U11>
         <PDBx:U12>-0.1583</PDBx:U12>
         <PDBx:U13>0.0831</PDBx:U13>
         <PDBx:U22>0.3782</PDBx:U22>
         <PDBx:U23>-0.0456</PDBx:U23>
         <PDBx:U33>0.2712</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="161">
         <PDBx:U11>0.5173</PDBx:U11>
         <PDBx:U12>-0.1643</PDBx:U12>
         <PDBx:U13>0.0840</PDBx:U13>
         <PDBx:U22>0.3953</PDBx:U22>
         <PDBx:U23>-0.0556</PDBx:U23>
         <PDBx:U33>0.3043</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="162">
         <PDBx:U11>0.4702</PDBx:U11>
         <PDBx:U12>-0.1492</PDBx:U12>
         <PDBx:U13>0.0858</PDBx:U13>
         <PDBx:U22>0.3635</PDBx:U22>
         <PDBx:U23>-0.0386</PDBx:U23>
         <PDBx:U33>0.2270</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="163">
         <PDBx:U11>0.5112</PDBx:U11>
         <PDBx:U12>-0.1397</PDBx:U12>
         <PDBx:U13>0.1129</PDBx:U13>
         <PDBx:U22>0.3982</PDBx:U22>
         <PDBx:U23>0.0048</PDBx:U23>
         <PDBx:U33>0.2718</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="164">
         <PDBx:U11>0.5517</PDBx:U11>
         <PDBx:U12>-0.1400</PDBx:U12>
         <PDBx:U13>0.1232</PDBx:U13>
         <PDBx:U22>0.4339</PDBx:U22>
         <PDBx:U23>0.0202</PDBx:U23>
         <PDBx:U33>0.3216</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="165">
         <PDBx:U11>0.6151</PDBx:U11>
         <PDBx:U12>-0.1482</PDBx:U12>
         <PDBx:U13>0.1253</PDBx:U13>
         <PDBx:U22>0.4934</PDBx:U22>
         <PDBx:U23>0.0130</PDBx:U23>
         <PDBx:U33>0.4056</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="166">
         <PDBx:U11>0.5897</PDBx:U11>
         <PDBx:U12>-0.1516</PDBx:U12>
         <PDBx:U13>0.1237</PDBx:U13>
         <PDBx:U22>0.4741</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.3829</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="167">
         <PDBx:U11>0.5543</PDBx:U11>
         <PDBx:U12>-0.1312</PDBx:U12>
         <PDBx:U13>0.1359</PDBx:U13>
         <PDBx:U22>0.4507</PDBx:U22>
         <PDBx:U23>0.0424</PDBx:U23>
         <PDBx:U33>0.3165</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="168">
         <PDBx:U11>0.5910</PDBx:U11>
         <PDBx:U12>-0.1200</PDBx:U12>
         <PDBx:U13>0.1360</PDBx:U13>
         <PDBx:U22>0.4925</PDBx:U22>
         <PDBx:U23>0.0539</PDBx:U23>
         <PDBx:U33>0.3322</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="169">
         <PDBx:U11>0.6256</PDBx:U11>
         <PDBx:U12>-0.1167</PDBx:U12>
         <PDBx:U13>0.1426</PDBx:U13>
         <PDBx:U22>0.5210</PDBx:U22>
         <PDBx:U23>0.0719</PDBx:U23>
         <PDBx:U33>0.3658</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="170">
         <PDBx:U11>0.6655</PDBx:U11>
         <PDBx:U12>-0.1119</PDBx:U12>
         <PDBx:U13>0.1288</PDBx:U13>
         <PDBx:U22>0.5787</PDBx:U22>
         <PDBx:U23>0.0468</PDBx:U23>
         <PDBx:U33>0.3874</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="171">
         <PDBx:U11>0.6543</PDBx:U11>
         <PDBx:U12>-0.1044</PDBx:U12>
         <PDBx:U13>0.1424</PDBx:U13>
         <PDBx:U22>0.5583</PDBx:U22>
         <PDBx:U23>0.0828</PDBx:U23>
         <PDBx:U33>0.3735</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="172">
         <PDBx:U11>0.6688</PDBx:U11>
         <PDBx:U12>-0.0998</PDBx:U12>
         <PDBx:U13>0.1279</PDBx:U13>
         <PDBx:U22>0.5911</PDBx:U22>
         <PDBx:U23>0.0562</PDBx:U23>
         <PDBx:U33>0.3703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="173">
         <PDBx:U11>0.7152</PDBx:U11>
         <PDBx:U12>-0.0954</PDBx:U12>
         <PDBx:U13>0.1349</PDBx:U13>
         <PDBx:U22>0.6346</PDBx:U22>
         <PDBx:U23>0.0745</PDBx:U23>
         <PDBx:U33>0.4149</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="174">
         <PDBx:U11>0.8102</PDBx:U11>
         <PDBx:U12>-0.0814</PDBx:U12>
         <PDBx:U13>0.1336</PDBx:U13>
         <PDBx:U22>0.7431</PDBx:U22>
         <PDBx:U23>0.0841</PDBx:U23>
         <PDBx:U33>0.4884</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="175">
         <PDBx:U11>0.5531</PDBx:U11>
         <PDBx:U12>-0.1517</PDBx:U12>
         <PDBx:U13>0.1291</PDBx:U13>
         <PDBx:U22>0.4204</PDBx:U22>
         <PDBx:U23>0.0200</PDBx:U23>
         <PDBx:U33>0.3562</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="176">
         <PDBx:U11>0.6136</PDBx:U11>
         <PDBx:U12>-0.1600</PDBx:U12>
         <PDBx:U13>0.1326</PDBx:U13>
         <PDBx:U22>0.4788</PDBx:U22>
         <PDBx:U23>0.0152</PDBx:U23>
         <PDBx:U33>0.4361</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="177">
         <PDBx:U11>0.6110</PDBx:U11>
         <PDBx:U12>-0.1622</PDBx:U12>
         <PDBx:U13>0.1455</PDBx:U13>
         <PDBx:U22>0.4892</PDBx:U22>
         <PDBx:U23>0.0327</PDBx:U23>
         <PDBx:U33>0.4441</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="178">
         <PDBx:U11>0.6178</PDBx:U11>
         <PDBx:U12>-0.1556</PDBx:U12>
         <PDBx:U13>0.1526</PDBx:U13>
         <PDBx:U22>0.5044</PDBx:U22>
         <PDBx:U23>0.0509</PDBx:U23>
         <PDBx:U33>0.4422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="179">
         <PDBx:U11>0.6720</PDBx:U11>
         <PDBx:U12>-0.1629</PDBx:U12>
         <PDBx:U13>0.1316</PDBx:U13>
         <PDBx:U22>0.5200</PDBx:U22>
         <PDBx:U23>0.0173</PDBx:U23>
         <PDBx:U33>0.5052</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="180">
         <PDBx:U11>0.6633</PDBx:U11>
         <PDBx:U12>-0.1714</PDBx:U12>
         <PDBx:U13>0.1356</PDBx:U13>
         <PDBx:U22>0.5110</PDBx:U22>
         <PDBx:U23>0.0154</PDBx:U23>
         <PDBx:U33>0.5177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="181">
         <PDBx:U11>0.6124</PDBx:U11>
         <PDBx:U12>-0.1704</PDBx:U12>
         <PDBx:U13>0.1488</PDBx:U13>
         <PDBx:U22>0.4958</PDBx:U22>
         <PDBx:U23>0.0282</PDBx:U23>
         <PDBx:U33>0.4640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="182">
         <PDBx:U11>0.7155</PDBx:U11>
         <PDBx:U12>-0.1746</PDBx:U12>
         <PDBx:U13>0.1615</PDBx:U13>
         <PDBx:U22>0.6129</PDBx:U22>
         <PDBx:U23>0.0472</PDBx:U23>
         <PDBx:U33>0.5829</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="183">
         <PDBx:U11>0.7879</PDBx:U11>
         <PDBx:U12>-0.1764</PDBx:U12>
         <PDBx:U13>0.1686</PDBx:U13>
         <PDBx:U22>0.6744</PDBx:U22>
         <PDBx:U23>0.0697</PDBx:U23>
         <PDBx:U33>0.6630</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="184">
         <PDBx:U11>0.7981</PDBx:U11>
         <PDBx:U12>-0.1786</PDBx:U12>
         <PDBx:U13>0.1633</PDBx:U13>
         <PDBx:U22>0.6640</PDBx:U22>
         <PDBx:U23>0.0662</PDBx:U23>
         <PDBx:U33>0.6755</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="185">
         <PDBx:U11>0.7438</PDBx:U11>
         <PDBx:U12>-0.1851</PDBx:U12>
         <PDBx:U13>0.1624</PDBx:U13>
         <PDBx:U22>0.6481</PDBx:U22>
         <PDBx:U23>0.0381</PDBx:U23>
         <PDBx:U33>0.6339</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="186">
         <PDBx:U11>0.7406</PDBx:U11>
         <PDBx:U12>-0.1826</PDBx:U12>
         <PDBx:U13>0.1567</PDBx:U13>
         <PDBx:U22>0.6569</PDBx:U22>
         <PDBx:U23>0.0179</PDBx:U23>
         <PDBx:U33>0.6223</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="187">
         <PDBx:U11>0.7776</PDBx:U11>
         <PDBx:U12>-0.1904</PDBx:U12>
         <PDBx:U13>0.1529</PDBx:U13>
         <PDBx:U22>0.6953</PDBx:U22>
         <PDBx:U23>0.0020</PDBx:U23>
         <PDBx:U33>0.6761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="188">
         <PDBx:U11>0.7563</PDBx:U11>
         <PDBx:U12>-0.1917</PDBx:U12>
         <PDBx:U13>0.1462</PDBx:U13>
         <PDBx:U22>0.6581</PDBx:U22>
         <PDBx:U23>-0.0077</PDBx:U23>
         <PDBx:U33>0.6572</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="189">
         <PDBx:U11>0.8226</PDBx:U11>
         <PDBx:U12>-0.1936</PDBx:U12>
         <PDBx:U13>0.1571</PDBx:U13>
         <PDBx:U22>0.7594</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.7315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="190">
         <PDBx:U11>0.8058</PDBx:U11>
         <PDBx:U12>-0.1744</PDBx:U12>
         <PDBx:U13>0.1806</PDBx:U13>
         <PDBx:U22>0.7069</PDBx:U22>
         <PDBx:U23>0.0936</PDBx:U23>
         <PDBx:U33>0.6832</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="191">
         <PDBx:U11>0.8607</PDBx:U11>
         <PDBx:U12>-0.1758</PDBx:U12>
         <PDBx:U13>0.1878</PDBx:U13>
         <PDBx:U22>0.7521</PDBx:U22>
         <PDBx:U23>0.1174</PDBx:U23>
         <PDBx:U33>0.7419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="192">
         <PDBx:U11>0.8917</PDBx:U11>
         <PDBx:U12>-0.1918</PDBx:U12>
         <PDBx:U13>0.1939</PDBx:U13>
         <PDBx:U22>0.7781</PDBx:U22>
         <PDBx:U23>0.1281</PDBx:U23>
         <PDBx:U33>0.8036</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="193">
         <PDBx:U11>0.9208</PDBx:U11>
         <PDBx:U12>-0.1978</PDBx:U12>
         <PDBx:U13>0.1942</PDBx:U13>
         <PDBx:U22>0.7851</PDBx:U22>
         <PDBx:U23>0.1373</PDBx:U23>
         <PDBx:U33>0.8397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="194">
         <PDBx:U11>0.8464</PDBx:U11>
         <PDBx:U12>-0.1644</PDBx:U12>
         <PDBx:U13>0.1969</PDBx:U13>
         <PDBx:U22>0.7583</PDBx:U22>
         <PDBx:U23>0.1397</PDBx:U23>
         <PDBx:U33>0.7099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="195">
         <PDBx:U11>1.1710</PDBx:U11>
         <PDBx:U12>-0.2503</PDBx:U12>
         <PDBx:U13>0.1383</PDBx:U13>
         <PDBx:U22>0.7944</PDBx:U22>
         <PDBx:U23>0.0884</PDBx:U23>
         <PDBx:U33>1.1740</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="196">
         <PDBx:U11>1.1815</PDBx:U11>
         <PDBx:U12>-0.2662</PDBx:U12>
         <PDBx:U13>0.1392</PDBx:U13>
         <PDBx:U22>0.8294</PDBx:U22>
         <PDBx:U23>0.0840</PDBx:U23>
         <PDBx:U33>1.2120</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="197">
         <PDBx:U11>1.1396</PDBx:U11>
         <PDBx:U12>-0.2586</PDBx:U12>
         <PDBx:U13>0.1330</PDBx:U13>
         <PDBx:U22>0.8206</PDBx:U22>
         <PDBx:U23>0.0613</PDBx:U23>
         <PDBx:U33>1.1683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="198">
         <PDBx:U11>1.1282</PDBx:U11>
         <PDBx:U12>-0.2645</PDBx:U12>
         <PDBx:U13>0.1378</PDBx:U13>
         <PDBx:U22>0.8393</PDBx:U22>
         <PDBx:U23>0.0606</PDBx:U23>
         <PDBx:U33>1.1682</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="199">
         <PDBx:U11>1.1920</PDBx:U11>
         <PDBx:U12>-0.2704</PDBx:U12>
         <PDBx:U13>0.1545</PDBx:U13>
         <PDBx:U22>0.8560</PDBx:U22>
         <PDBx:U23>0.1084</PDBx:U23>
         <PDBx:U33>1.2214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="200">
         <PDBx:U11>1.2276</PDBx:U11>
         <PDBx:U12>-0.2666</PDBx:U12>
         <PDBx:U13>0.1603</PDBx:U13>
         <PDBx:U22>0.8581</PDBx:U22>
         <PDBx:U23>0.1286</PDBx:U23>
         <PDBx:U33>1.2407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="201">
         <PDBx:U11>1.2075</PDBx:U11>
         <PDBx:U12>-0.2492</PDBx:U12>
         <PDBx:U13>0.1512</PDBx:U13>
         <PDBx:U22>0.8192</PDBx:U22>
         <PDBx:U23>0.1154</PDBx:U23>
         <PDBx:U33>1.1978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="202">
         <PDBx:U11>1.1161</PDBx:U11>
         <PDBx:U12>-0.2451</PDBx:U12>
         <PDBx:U13>0.1230</PDBx:U13>
         <PDBx:U22>0.7914</PDBx:U22>
         <PDBx:U23>0.0442</PDBx:U23>
         <PDBx:U33>1.1297</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="203">
         <PDBx:U11>1.0187</PDBx:U11>
         <PDBx:U12>-0.2375</PDBx:U12>
         <PDBx:U13>0.1169</PDBx:U13>
         <PDBx:U22>0.7224</PDBx:U22>
         <PDBx:U23>0.0231</PDBx:U23>
         <PDBx:U33>1.0288</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="204">
         <PDBx:U11>0.9855</PDBx:U11>
         <PDBx:U12>-0.2445</PDBx:U12>
         <PDBx:U13>0.1049</PDBx:U13>
         <PDBx:U22>0.6849</PDBx:U22>
         <PDBx:U23>0.0053</PDBx:U23>
         <PDBx:U33>1.0162</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="205">
         <PDBx:U11>1.0540</PDBx:U11>
         <PDBx:U12>-0.2451</PDBx:U12>
         <PDBx:U13>0.0963</PDBx:U13>
         <PDBx:U22>0.7237</PDBx:U22>
         <PDBx:U23>0.0025</PDBx:U23>
         <PDBx:U33>1.0881</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="206">
         <PDBx:U11>1.0306</PDBx:U11>
         <PDBx:U12>-0.2182</PDBx:U12>
         <PDBx:U13>0.1135</PDBx:U13>
         <PDBx:U22>0.7365</PDBx:U22>
         <PDBx:U23>0.0165</PDBx:U23>
         <PDBx:U33>1.0113</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="207">
         <PDBx:U11>1.0608</PDBx:U11>
         <PDBx:U12>-0.2104</PDBx:U12>
         <PDBx:U13>0.1228</PDBx:U13>
         <PDBx:U22>0.7759</PDBx:U22>
         <PDBx:U23>0.0301</PDBx:U23>
         <PDBx:U33>1.0198</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="208">
         <PDBx:U11>1.0238</PDBx:U11>
         <PDBx:U12>-0.2099</PDBx:U12>
         <PDBx:U13>0.1283</PDBx:U13>
         <PDBx:U22>0.7684</PDBx:U22>
         <PDBx:U23>0.0288</PDBx:U23>
         <PDBx:U33>0.9788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="209">
         <PDBx:U11>1.1145</PDBx:U11>
         <PDBx:U12>-0.2024</PDBx:U12>
         <PDBx:U13>0.1250</PDBx:U13>
         <PDBx:U22>0.8087</PDBx:U22>
         <PDBx:U23>0.0437</PDBx:U23>
         <PDBx:U33>1.0557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="210">
         <PDBx:U11>1.0397</PDBx:U11>
         <PDBx:U12>-0.2022</PDBx:U12>
         <PDBx:U13>0.1349</PDBx:U13>
         <PDBx:U22>0.7923</PDBx:U22>
         <PDBx:U23>0.0404</PDBx:U23>
         <PDBx:U33>0.9747</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="211">
         <PDBx:U11>1.1144</PDBx:U11>
         <PDBx:U12>-0.1946</PDBx:U12>
         <PDBx:U13>0.1323</PDBx:U13>
         <PDBx:U22>0.8188</PDBx:U22>
         <PDBx:U23>0.0560</PDBx:U23>
         <PDBx:U33>1.0356</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="212">
         <PDBx:U11>1.0746</PDBx:U11>
         <PDBx:U12>-0.1946</PDBx:U12>
         <PDBx:U13>0.1366</PDBx:U13>
         <PDBx:U22>0.8083</PDBx:U22>
         <PDBx:U23>0.0540</PDBx:U23>
         <PDBx:U33>0.9933</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="213">
         <PDBx:U11>0.8820</PDBx:U11>
         <PDBx:U12>-0.2492</PDBx:U12>
         <PDBx:U13>0.1041</PDBx:U13>
         <PDBx:U22>0.6103</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.9256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="214">
         <PDBx:U11>0.7971</PDBx:U11>
         <PDBx:U12>-0.2533</PDBx:U12>
         <PDBx:U13>0.0922</PDBx:U13>
         <PDBx:U22>0.5273</PDBx:U22>
         <PDBx:U23>-0.0251</PDBx:U23>
         <PDBx:U33>0.8576</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="215">
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="248">
         <PDBx:U11>1.0638</PDBx:U11>
         <PDBx:U12>-0.2386</PDBx:U12>
         <PDBx:U13>0.1461</PDBx:U13>
         <PDBx:U22>0.9114</PDBx:U22>
         <PDBx:U23>-0.0908</PDBx:U23>
         <PDBx:U33>1.0158</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="249">
         <PDBx:U11>1.1276</PDBx:U11>
         <PDBx:U12>-0.2426</PDBx:U12>
         <PDBx:U13>0.1621</PDBx:U13>
         <PDBx:U22>0.9464</PDBx:U22>
         <PDBx:U23>-0.0984</PDBx:U23>
         <PDBx:U33>1.1046</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="250">
         <PDBx:U11>0.6105</PDBx:U11>
         <PDBx:U12>-0.2778</PDBx:U12>
         <PDBx:U13>0.1086</PDBx:U13>
         <PDBx:U22>0.5324</PDBx:U22>
         <PDBx:U23>-0.0839</PDBx:U23>
         <PDBx:U33>0.4953</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="251">
         <PDBx:U11>0.5850</PDBx:U11>
         <PDBx:U12>-0.2776</PDBx:U12>
         <PDBx:U13>0.1062</PDBx:U13>
         <PDBx:U22>0.5187</PDBx:U22>
         <PDBx:U23>-0.0869</PDBx:U23>
         <PDBx:U33>0.4346</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="252">
         <PDBx:U11>0.5556</PDBx:U11>
         <PDBx:U12>-0.2696</PDBx:U12>
         <PDBx:U13>0.0953</PDBx:U13>
         <PDBx:U22>0.5171</PDBx:U22>
         <PDBx:U23>-0.0709</PDBx:U23>
         <PDBx:U33>0.4130</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="253">
         <PDBx:U11>0.5519</PDBx:U11>
         <PDBx:U12>-0.2595</PDBx:U12>
         <PDBx:U13>0.0944</PDBx:U13>
         <PDBx:U22>0.5156</PDBx:U22>
         <PDBx:U23>-0.0713</PDBx:U23>
         <PDBx:U33>0.3943</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="254">
         <PDBx:U11>0.6104</PDBx:U11>
         <PDBx:U12>-0.3017</PDBx:U12>
         <PDBx:U13>0.1041</PDBx:U13>
         <PDBx:U22>0.5545</PDBx:U22>
         <PDBx:U23>-0.0950</PDBx:U23>
         <PDBx:U33>0.4275</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="255">
         <PDBx:U11>0.6310</PDBx:U11>
         <PDBx:U12>-0.3102</PDBx:U12>
         <PDBx:U13>0.1178</PDBx:U13>
         <PDBx:U22>0.5499</PDBx:U22>
         <PDBx:U23>-0.1127</PDBx:U23>
         <PDBx:U33>0.4314</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="256">
         <PDBx:U11>0.7523</PDBx:U11>
         <PDBx:U12>-0.2933</PDBx:U12>
         <PDBx:U13>0.1313</PDBx:U13>
         <PDBx:U22>0.6530</PDBx:U22>
         <PDBx:U23>-0.1202</PDBx:U23>
         <PDBx:U33>0.5340</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="257">
         <PDBx:U11>0.6940</PDBx:U11>
         <PDBx:U12>-0.3030</PDBx:U12>
         <PDBx:U13>0.1224</PDBx:U13>
         <PDBx:U22>0.6215</PDBx:U22>
         <PDBx:U23>-0.1144</PDBx:U23>
         <PDBx:U33>0.4390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="258">
         <PDBx:U11>0.5770</PDBx:U11>
         <PDBx:U12>-0.2746</PDBx:U12>
         <PDBx:U13>0.0878</PDBx:U13>
         <PDBx:U22>0.5614</PDBx:U22>
         <PDBx:U23>-0.0558</PDBx:U23>
         <PDBx:U33>0.4599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="259">
         <PDBx:U11>0.4729</PDBx:U11>
         <PDBx:U12>-0.2667</PDBx:U12>
         <PDBx:U13>0.0798</PDBx:U13>
         <PDBx:U22>0.4903</PDBx:U22>
         <PDBx:U23>-0.0381</PDBx:U23>
         <PDBx:U33>0.3665</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="260">
         <PDBx:U11>0.4814</PDBx:U11>
         <PDBx:U12>-0.2442</PDBx:U12>
         <PDBx:U13>0.0844</PDBx:U13>
         <PDBx:U22>0.4886</PDBx:U22>
         <PDBx:U23>-0.0348</PDBx:U23>
         <PDBx:U33>0.3879</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="261">
         <PDBx:U11>0.5049</PDBx:U11>
         <PDBx:U12>-0.2358</PDBx:U12>
         <PDBx:U13>0.0814</PDBx:U13>
         <PDBx:U22>0.5252</PDBx:U22>
         <PDBx:U23>-0.0320</PDBx:U23>
         <PDBx:U33>0.3995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="262">
         <PDBx:U11>0.4578</PDBx:U11>
         <PDBx:U12>-0.2352</PDBx:U12>
         <PDBx:U13>0.0911</PDBx:U13>
         <PDBx:U22>0.4433</PDBx:U22>
         <PDBx:U23>-0.0342</PDBx:U23>
         <PDBx:U33>0.3901</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="263">
         <PDBx:U11>0.4451</PDBx:U11>
         <PDBx:U12>-0.2156</PDBx:U12>
         <PDBx:U13>0.0947</PDBx:U13>
         <PDBx:U22>0.4224</PDBx:U22>
         <PDBx:U23>-0.0298</PDBx:U23>
         <PDBx:U33>0.3912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="264">
         <PDBx:U11>0.4534</PDBx:U11>
         <PDBx:U12>-0.2071</PDBx:U12>
         <PDBx:U13>0.0982</PDBx:U13>
         <PDBx:U22>0.4095</PDBx:U22>
         <PDBx:U23>-0.0452</PDBx:U23>
         <PDBx:U33>0.3722</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="265">
         <PDBx:U11>0.4885</PDBx:U11>
         <PDBx:U12>-0.1964</PDBx:U12>
         <PDBx:U13>0.0967</PDBx:U13>
         <PDBx:U22>0.4505</PDBx:U22>
         <PDBx:U23>-0.0423</PDBx:U23>
         <PDBx:U33>0.4032</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="266">
         <PDBx:U11>0.5207</PDBx:U11>
         <PDBx:U12>-0.2101</PDBx:U12>
         <PDBx:U13>0.0993</PDBx:U13>
         <PDBx:U22>0.4813</PDBx:U22>
         <PDBx:U23>-0.0245</PDBx:U23>
         <PDBx:U33>0.5000</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="267">
         <PDBx:U11>0.5849</PDBx:U11>
         <PDBx:U12>-0.2151</PDBx:U12>
         <PDBx:U13>0.0967</PDBx:U13>
         <PDBx:U22>0.5660</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.6018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="268">
         <PDBx:U11>0.6221</PDBx:U11>
         <PDBx:U12>-0.2157</PDBx:U12>
         <PDBx:U13>0.1024</PDBx:U13>
         <PDBx:U22>0.5815</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.6644</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="269">
         <PDBx:U11>0.5797</PDBx:U11>
         <PDBx:U12>-0.2047</PDBx:U12>
         <PDBx:U13>0.0952</PDBx:U13>
         <PDBx:U22>0.5947</PDBx:U22>
         <PDBx:U23>0.0161</PDBx:U23>
         <PDBx:U33>0.6097</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="270">
         <PDBx:U11>0.4744</PDBx:U11>
         <PDBx:U12>-0.2122</PDBx:U12>
         <PDBx:U13>0.1041</PDBx:U13>
         <PDBx:U22>0.4075</PDBx:U22>
         <PDBx:U23>-0.0606</PDBx:U23>
         <PDBx:U33>0.3755</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="271">
         <PDBx:U11>0.4773</PDBx:U11>
         <PDBx:U12>-0.2038</PDBx:U12>
         <PDBx:U13>0.1096</PDBx:U13>
         <PDBx:U22>0.3928</PDBx:U22>
         <PDBx:U23>-0.0723</PDBx:U23>
         <PDBx:U33>0.3562</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="272">
         <PDBx:U11>0.5051</PDBx:U11>
         <PDBx:U12>-0.2081</PDBx:U12>
         <PDBx:U13>0.1036</PDBx:U13>
         <PDBx:U22>0.4337</PDBx:U22>
         <PDBx:U23>-0.0734</PDBx:U23>
         <PDBx:U33>0.3569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="273">
         <PDBx:U11>0.4879</PDBx:U11>
         <PDBx:U12>-0.1970</PDBx:U12>
         <PDBx:U13>0.1044</PDBx:U13>
         <PDBx:U22>0.4092</PDBx:U22>
         <PDBx:U23>-0.0751</PDBx:U23>
         <PDBx:U33>0.3328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="274">
         <PDBx:U11>0.4757</PDBx:U11>
         <PDBx:U12>-0.2102</PDBx:U12>
         <PDBx:U13>0.1197</PDBx:U13>
         <PDBx:U22>0.3719</PDBx:U22>
         <PDBx:U23>-0.0854</PDBx:U23>
         <PDBx:U33>0.3419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="275">
         <PDBx:U11>0.5538</PDBx:U11>
         <PDBx:U12>-0.2112</PDBx:U12>
         <PDBx:U13>0.1307</PDBx:U13>
         <PDBx:U22>0.4323</PDBx:U22>
         <PDBx:U23>-0.0894</PDBx:U23>
         <PDBx:U33>0.4400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="276">
         <PDBx:U11>0.6080</PDBx:U11>
         <PDBx:U12>-0.2202</PDBx:U12>
         <PDBx:U13>0.1461</PDBx:U13>
         <PDBx:U22>0.4678</PDBx:U22>
         <PDBx:U23>-0.1056</PDBx:U23>
         <PDBx:U33>0.4750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="277">
         <PDBx:U11>0.4990</PDBx:U11>
         <PDBx:U12>-0.1938</PDBx:U12>
         <PDBx:U13>0.1337</PDBx:U13>
         <PDBx:U22>0.3706</PDBx:U22>
         <PDBx:U23>-0.0835</PDBx:U23>
         <PDBx:U33>0.4075</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="278">
         <PDBx:U11>0.4928</PDBx:U11>
         <PDBx:U12>-0.2251</PDBx:U12>
         <PDBx:U13>0.0967</PDBx:U13>
         <PDBx:U22>0.4423</PDBx:U22>
         <PDBx:U23>-0.0710</PDBx:U23>
         <PDBx:U33>0.3314</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="279">
         <PDBx:U11>0.4991</PDBx:U11>
         <PDBx:U12>-0.2313</PDBx:U12>
         <PDBx:U13>0.0885</PDBx:U13>
         <PDBx:U22>0.4675</PDBx:U22>
         <PDBx:U23>-0.0689</PDBx:U23>
         <PDBx:U33>0.3161</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="280">
         <PDBx:U11>0.5464</PDBx:U11>
         <PDBx:U12>-0.2199</PDBx:U12>
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         <PDBx:U22>0.5349</PDBx:U22>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="297">
         <PDBx:U11>0.4603</PDBx:U11>
         <PDBx:U12>-0.1657</PDBx:U12>
         <PDBx:U13>0.1017</PDBx:U13>
         <PDBx:U22>0.3930</PDBx:U22>
         <PDBx:U23>-0.0522</PDBx:U23>
         <PDBx:U33>0.3629</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="298">
         <PDBx:U11>0.4464</PDBx:U11>
         <PDBx:U12>-0.1512</PDBx:U12>
         <PDBx:U13>0.1058</PDBx:U13>
         <PDBx:U22>0.3597</PDBx:U22>
         <PDBx:U23>-0.0555</PDBx:U23>
         <PDBx:U33>0.3563</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="299">
         <PDBx:U11>0.4081</PDBx:U11>
         <PDBx:U12>-0.1450</PDBx:U12>
         <PDBx:U13>0.1042</PDBx:U13>
         <PDBx:U22>0.3342</PDBx:U22>
         <PDBx:U23>-0.0468</PDBx:U23>
         <PDBx:U33>0.3280</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="300">
         <PDBx:U11>0.5101</PDBx:U11>
         <PDBx:U12>-0.1465</PDBx:U12>
         <PDBx:U13>0.1099</PDBx:U13>
         <PDBx:U22>0.4116</PDBx:U22>
         <PDBx:U23>-0.0543</PDBx:U23>
         <PDBx:U33>0.4409</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="301">
         <PDBx:U11>0.4294</PDBx:U11>
         <PDBx:U12>-0.1774</PDBx:U12>
         <PDBx:U13>0.0989</PDBx:U13>
         <PDBx:U22>0.3522</PDBx:U22>
         <PDBx:U23>-0.0701</PDBx:U23>
         <PDBx:U33>0.2724</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="302">
         <PDBx:U11>0.4860</PDBx:U11>
         <PDBx:U12>-0.1758</PDBx:U12>
         <PDBx:U13>0.1013</PDBx:U13>
         <PDBx:U22>0.3941</PDBx:U22>
         <PDBx:U23>-0.0767</PDBx:U23>
         <PDBx:U33>0.3080</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="303">
         <PDBx:U11>0.4636</PDBx:U11>
         <PDBx:U12>-0.1809</PDBx:U12>
         <PDBx:U13>0.0928</PDBx:U13>
         <PDBx:U22>0.3836</PDBx:U22>
         <PDBx:U23>-0.0732</PDBx:U23>
         <PDBx:U33>0.2774</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="304">
         <PDBx:U11>0.4712</PDBx:U11>
         <PDBx:U12>-0.1721</PDBx:U12>
         <PDBx:U13>0.0934</PDBx:U13>
         <PDBx:U22>0.3776</PDBx:U22>
         <PDBx:U23>-0.0722</PDBx:U23>
         <PDBx:U33>0.2844</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="305">
         <PDBx:U11>0.4740</PDBx:U11>
         <PDBx:U12>-0.1857</PDBx:U12>
         <PDBx:U13>0.1047</PDBx:U13>
         <PDBx:U22>0.3790</PDBx:U22>
         <PDBx:U23>-0.0814</PDBx:U23>
         <PDBx:U33>0.2803</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="306">
         <PDBx:U11>0.4796</PDBx:U11>
         <PDBx:U12>-0.1878</PDBx:U12>
         <PDBx:U13>0.0854</PDBx:U13>
         <PDBx:U22>0.4351</PDBx:U22>
         <PDBx:U23>-0.0617</PDBx:U23>
         <PDBx:U33>0.2996</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="307">
         <PDBx:U11>0.5057</PDBx:U11>
         <PDBx:U12>-0.1766</PDBx:U12>
         <PDBx:U13>0.0801</PDBx:U13>
         <PDBx:U22>0.4913</PDBx:U22>
         <PDBx:U23>-0.0488</PDBx:U23>
         <PDBx:U33>0.3213</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="308">
         <PDBx:U11>0.4530</PDBx:U11>
         <PDBx:U12>-0.1522</PDBx:U12>
         <PDBx:U13>0.0825</PDBx:U13>
         <PDBx:U22>0.4390</PDBx:U22>
         <PDBx:U23>-0.0470</PDBx:U23>
         <PDBx:U33>0.2694</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="309">
         <PDBx:U11>0.4695</PDBx:U11>
         <PDBx:U12>-0.1354</PDBx:U12>
         <PDBx:U13>0.0794</PDBx:U13>
         <PDBx:U22>0.4505</PDBx:U22>
         <PDBx:U23>-0.0484</PDBx:U23>
         <PDBx:U33>0.2730</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="310">
         <PDBx:U11>0.5529</PDBx:U11>
         <PDBx:U12>-0.1800</PDBx:U12>
         <PDBx:U13>0.0732</PDBx:U13>
         <PDBx:U22>0.5849</PDBx:U22>
         <PDBx:U23>-0.0348</PDBx:U23>
         <PDBx:U33>0.3730</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="311">
         <PDBx:U11>0.6042</PDBx:U11>
         <PDBx:U12>-0.1582</PDBx:U12>
         <PDBx:U13>0.0676</PDBx:U13>
         <PDBx:U22>0.6709</PDBx:U22>
         <PDBx:U23>-0.0214</PDBx:U23>
         <PDBx:U33>0.4179</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="312">
         <PDBx:U11>0.6377</PDBx:U11>
         <PDBx:U12>-0.1587</PDBx:U12>
         <PDBx:U13>0.0625</PDBx:U13>
         <PDBx:U22>0.7095</PDBx:U22>
         <PDBx:U23>-0.0182</PDBx:U23>
         <PDBx:U33>0.4400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="313">
         <PDBx:U11>0.6172</PDBx:U11>
         <PDBx:U12>-0.1387</PDBx:U12>
         <PDBx:U13>0.0681</PDBx:U13>
         <PDBx:U22>0.7070</PDBx:U22>
         <PDBx:U23>-0.0140</PDBx:U23>
         <PDBx:U33>0.4367</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="314">
         <PDBx:U11>0.4006</PDBx:U11>
         <PDBx:U12>-0.1489</PDBx:U12>
         <PDBx:U13>0.0866</PDBx:U13>
         <PDBx:U22>0.3924</PDBx:U22>
         <PDBx:U23>-0.0451</PDBx:U23>
         <PDBx:U33>0.2311</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="315">
         <PDBx:U11>0.4109</PDBx:U11>
         <PDBx:U12>-0.1262</PDBx:U12>
         <PDBx:U13>0.0878</PDBx:U13>
         <PDBx:U22>0.4056</PDBx:U22>
         <PDBx:U23>-0.0462</PDBx:U23>
         <PDBx:U33>0.2391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="316">
         <PDBx:U11>0.3707</PDBx:U11>
         <PDBx:U12>-0.1233</PDBx:U12>
         <PDBx:U13>0.0907</PDBx:U13>
         <PDBx:U22>0.3199</PDBx:U22>
         <PDBx:U23>-0.0604</PDBx:U23>
         <PDBx:U33>0.1944</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="317">
         <PDBx:U11>0.4051</PDBx:U11>
         <PDBx:U12>-0.1009</PDBx:U12>
         <PDBx:U13>0.0838</PDBx:U13>
         <PDBx:U22>0.3484</PDBx:U22>
         <PDBx:U23>-0.0656</PDBx:U23>
         <PDBx:U33>0.2243</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="318">
         <PDBx:U11>0.4118</PDBx:U11>
         <PDBx:U12>-0.1252</PDBx:U12>
         <PDBx:U13>0.0914</PDBx:U13>
         <PDBx:U22>0.4296</PDBx:U22>
         <PDBx:U23>-0.0370</PDBx:U23>
         <PDBx:U33>0.2584</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="319">
         <PDBx:U11>0.3626</PDBx:U11>
         <PDBx:U12>-0.1181</PDBx:U12>
         <PDBx:U13>0.0865</PDBx:U13>
         <PDBx:U22>0.4323</PDBx:U22>
         <PDBx:U23>-0.0204</PDBx:U23>
         <PDBx:U33>0.2148</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="320">
         <PDBx:U11>0.3641</PDBx:U11>
         <PDBx:U12>-0.1168</PDBx:U12>
         <PDBx:U13>0.0898</PDBx:U13>
         <PDBx:U22>0.4569</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.2378</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="321">
         <PDBx:U11>0.3893</PDBx:U11>
         <PDBx:U12>-0.1386</PDBx:U12>
         <PDBx:U13>0.0924</PDBx:U13>
         <PDBx:U22>0.4618</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.2843</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="322">
         <PDBx:U11>0.4394</PDBx:U11>
         <PDBx:U12>-0.1403</PDBx:U12>
         <PDBx:U13>0.0971</PDBx:U13>
         <PDBx:U22>0.4920</PDBx:U22>
         <PDBx:U23>-0.0073</PDBx:U23>
         <PDBx:U33>0.3525</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="323">
         <PDBx:U11>0.4016</PDBx:U11>
         <PDBx:U12>-0.1274</PDBx:U12>
         <PDBx:U13>0.1009</PDBx:U13>
         <PDBx:U22>0.4557</PDBx:U22>
         <PDBx:U23>-0.0076</PDBx:U23>
         <PDBx:U33>0.3134</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="324">
         <PDBx:U11>0.4155</PDBx:U11>
         <PDBx:U12>-0.1516</PDBx:U12>
         <PDBx:U13>0.0972</PDBx:U13>
         <PDBx:U22>0.4485</PDBx:U22>
         <PDBx:U23>-0.0073</PDBx:U23>
         <PDBx:U33>0.3469</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="325">
         <PDBx:U11>0.3846</PDBx:U11>
         <PDBx:U12>-0.1438</PDBx:U12>
         <PDBx:U13>0.0980</PDBx:U13>
         <PDBx:U22>0.3017</PDBx:U22>
         <PDBx:U23>-0.0663</PDBx:U23>
         <PDBx:U33>0.2160</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="326">
         <PDBx:U11>0.4589</PDBx:U11>
         <PDBx:U12>-0.1396</PDBx:U12>
         <PDBx:U13>0.1004</PDBx:U13>
         <PDBx:U22>0.3407</PDBx:U22>
         <PDBx:U23>-0.0719</PDBx:U23>
         <PDBx:U33>0.2969</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="327">
         <PDBx:U11>0.5138</PDBx:U11>
         <PDBx:U12>-0.1293</PDBx:U12>
         <PDBx:U13>0.0918</PDBx:U13>
         <PDBx:U22>0.3857</PDBx:U22>
         <PDBx:U23>-0.0722</PDBx:U23>
         <PDBx:U33>0.3433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="328">
         <PDBx:U11>0.4259</PDBx:U11>
         <PDBx:U12>-0.1134</PDBx:U12>
         <PDBx:U13>0.0857</PDBx:U13>
         <PDBx:U22>0.2833</PDBx:U22>
         <PDBx:U23>-0.0732</PDBx:U23>
         <PDBx:U33>0.2634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="329">
         <PDBx:U11>0.4837</PDBx:U11>
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         <PDBx:U13>0.1070</PDBx:U13>
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         <PDBx:U23>-0.0704</PDBx:U23>
         <PDBx:U33>0.3314</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="330">
         <PDBx:U11>0.4487</PDBx:U11>
         <PDBx:U12>-0.1339</PDBx:U12>
         <PDBx:U13>0.1079</PDBx:U13>
         <PDBx:U22>0.3314</PDBx:U22>
         <PDBx:U23>-0.0696</PDBx:U23>
         <PDBx:U33>0.3158</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="331">
         <PDBx:U11>0.4132</PDBx:U11>
         <PDBx:U12>-0.1272</PDBx:U12>
         <PDBx:U13>0.1109</PDBx:U13>
         <PDBx:U22>0.2903</PDBx:U22>
         <PDBx:U23>-0.0688</PDBx:U23>
         <PDBx:U33>0.2950</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="332">
         <PDBx:U11>0.4305</PDBx:U11>
         <PDBx:U12>-0.1346</PDBx:U12>
         <PDBx:U13>0.1130</PDBx:U13>
         <PDBx:U22>0.3094</PDBx:U22>
         <PDBx:U23>-0.0713</PDBx:U23>
         <PDBx:U33>0.3081</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="333">
         <PDBx:U11>0.4283</PDBx:U11>
         <PDBx:U12>-0.1164</PDBx:U12>
         <PDBx:U13>0.1109</PDBx:U13>
         <PDBx:U22>0.3000</PDBx:U22>
         <PDBx:U23>-0.0659</PDBx:U23>
         <PDBx:U33>0.3254</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="334">
         <PDBx:U11>0.4780</PDBx:U11>
         <PDBx:U12>-0.1396</PDBx:U12>
         <PDBx:U13>0.0903</PDBx:U13>
         <PDBx:U22>0.3602</PDBx:U22>
         <PDBx:U23>-0.0707</PDBx:U23>
         <PDBx:U33>0.2922</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="335">
         <PDBx:U11>0.4510</PDBx:U11>
         <PDBx:U12>-0.1334</PDBx:U12>
         <PDBx:U13>0.0845</PDBx:U13>
         <PDBx:U22>0.3235</PDBx:U22>
         <PDBx:U23>-0.0707</PDBx:U23>
         <PDBx:U33>0.2525</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="336">
         <PDBx:U11>0.4954</PDBx:U11>
         <PDBx:U12>-0.1069</PDBx:U12>
         <PDBx:U13>0.0756</PDBx:U13>
         <PDBx:U22>0.3665</PDBx:U22>
         <PDBx:U23>-0.0753</PDBx:U23>
         <PDBx:U33>0.2885</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="337">
         <PDBx:U11>0.4863</PDBx:U11>
         <PDBx:U12>-0.0982</PDBx:U12>
         <PDBx:U13>0.0712</PDBx:U13>
         <PDBx:U22>0.3319</PDBx:U22>
         <PDBx:U23>-0.0786</PDBx:U23>
         <PDBx:U33>0.2797</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="338">
         <PDBx:U11>0.4896</PDBx:U11>
         <PDBx:U12>-0.1473</PDBx:U12>
         <PDBx:U13>0.0828</PDBx:U13>
         <PDBx:U22>0.3851</PDBx:U22>
         <PDBx:U23>-0.0647</PDBx:U23>
         <PDBx:U33>0.2758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="339">
         <PDBx:U11>0.5667</PDBx:U11>
         <PDBx:U12>-0.1735</PDBx:U12>
         <PDBx:U13>0.0894</PDBx:U13>
         <PDBx:U22>0.4517</PDBx:U22>
         <PDBx:U23>-0.0653</PDBx:U23>
         <PDBx:U33>0.3557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="340">
         <PDBx:U11>0.5972</PDBx:U11>
         <PDBx:U12>-0.1851</PDBx:U12>
         <PDBx:U13>0.0812</PDBx:U13>
         <PDBx:U22>0.5136</PDBx:U22>
         <PDBx:U23>-0.0608</PDBx:U23>
         <PDBx:U33>0.3771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="341">
         <PDBx:U11>0.6135</PDBx:U11>
         <PDBx:U12>-0.1687</PDBx:U12>
         <PDBx:U13>0.0949</PDBx:U13>
         <PDBx:U22>0.4755</PDBx:U22>
         <PDBx:U23>-0.0635</PDBx:U23>
         <PDBx:U33>0.3980</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="342">
         <PDBx:U11>0.4858</PDBx:U11>
         <PDBx:U12>-0.0922</PDBx:U12>
         <PDBx:U13>0.0722</PDBx:U13>
         <PDBx:U22>0.3874</PDBx:U22>
         <PDBx:U23>-0.0726</PDBx:U23>
         <PDBx:U33>0.2777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="343">
         <PDBx:U11>0.5032</PDBx:U11>
         <PDBx:U12>-0.0626</PDBx:U12>
         <PDBx:U13>0.0633</PDBx:U13>
         <PDBx:U22>0.4091</PDBx:U22>
         <PDBx:U23>-0.0757</PDBx:U23>
         <PDBx:U33>0.2937</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="344">
         <PDBx:U11>0.4665</PDBx:U11>
         <PDBx:U12>-0.0544</PDBx:U12>
         <PDBx:U13>0.0608</PDBx:U13>
         <PDBx:U22>0.3376</PDBx:U22>
         <PDBx:U23>-0.0890</PDBx:U23>
         <PDBx:U33>0.2634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="345">
         <PDBx:U11>0.4833</PDBx:U11>
         <PDBx:U12>-0.0381</PDBx:U12>
         <PDBx:U13>0.0533</PDBx:U13>
         <PDBx:U22>0.3338</PDBx:U22>
         <PDBx:U23>-0.0961</PDBx:U23>
         <PDBx:U33>0.2787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="346">
         <PDBx:U11>0.5709</PDBx:U11>
         <PDBx:U12>-0.0475</PDBx:U12>
         <PDBx:U13>0.0620</PDBx:U13>
         <PDBx:U22>0.5216</PDBx:U22>
         <PDBx:U23>-0.0692</PDBx:U23>
         <PDBx:U33>0.3615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="347">
         <PDBx:U11>0.5371</PDBx:U11>
         <PDBx:U12>-0.0153</PDBx:U12>
         <PDBx:U13>0.0544</PDBx:U13>
         <PDBx:U22>0.4905</PDBx:U22>
         <PDBx:U23>-0.0758</PDBx:U23>
         <PDBx:U33>0.3233</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="348">
         <PDBx:U11>0.5942</PDBx:U11>
         <PDBx:U12>-0.0575</PDBx:U12>
         <PDBx:U13>0.0633</PDBx:U13>
         <PDBx:U22>0.5830</PDBx:U22>
         <PDBx:U23>-0.0538</PDBx:U23>
         <PDBx:U33>0.3820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="349">
         <PDBx:U11>0.4572</PDBx:U11>
         <PDBx:U12>-0.0649</PDBx:U12>
         <PDBx:U13>0.0651</PDBx:U13>
         <PDBx:U22>0.3257</PDBx:U22>
         <PDBx:U23>-0.0886</PDBx:U23>
         <PDBx:U33>0.2692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="350">
         <PDBx:U11>0.4525</PDBx:U11>
         <PDBx:U12>-0.0573</PDBx:U12>
         <PDBx:U13>0.0589</PDBx:U13>
         <PDBx:U22>0.3029</PDBx:U22>
         <PDBx:U23>-0.0920</PDBx:U23>
         <PDBx:U33>0.2838</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="351">
         <PDBx:U11>0.4703</PDBx:U11>
         <PDBx:U12>-0.0626</PDBx:U12>
         <PDBx:U13>0.0562</PDBx:U13>
         <PDBx:U22>0.2985</PDBx:U22>
         <PDBx:U23>-0.0868</PDBx:U23>
         <PDBx:U33>0.3179</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="352">
         <PDBx:U11>0.4761</PDBx:U11>
         <PDBx:U12>-0.0511</PDBx:U12>
         <PDBx:U13>0.0460</PDBx:U13>
         <PDBx:U22>0.2932</PDBx:U22>
         <PDBx:U23>-0.0898</PDBx:U23>
         <PDBx:U33>0.3363</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="353">
         <PDBx:U11>0.4309</PDBx:U11>
         <PDBx:U12>-0.0672</PDBx:U12>
         <PDBx:U13>0.0659</PDBx:U13>
         <PDBx:U22>0.2892</PDBx:U22>
         <PDBx:U23>-0.0887</PDBx:U23>
         <PDBx:U33>0.2744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="354">
         <PDBx:U11>0.4662</PDBx:U11>
         <PDBx:U12>-0.0568</PDBx:U12>
         <PDBx:U13>0.0670</PDBx:U13>
         <PDBx:U22>0.3522</PDBx:U22>
         <PDBx:U23>-0.0926</PDBx:U23>
         <PDBx:U33>0.2964</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="355">
         <PDBx:U11>0.4852</PDBx:U11>
         <PDBx:U12>-0.0366</PDBx:U12>
         <PDBx:U13>0.0583</PDBx:U13>
         <PDBx:U22>0.3761</PDBx:U22>
         <PDBx:U23>-0.1010</PDBx:U23>
         <PDBx:U33>0.3110</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="356">
         <PDBx:U11>0.4347</PDBx:U11>
         <PDBx:U12>-0.0611</PDBx:U12>
         <PDBx:U13>0.0731</PDBx:U13>
         <PDBx:U22>0.3565</PDBx:U22>
         <PDBx:U23>-0.0824</PDBx:U23>
         <PDBx:U33>0.2639</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="357">
         <PDBx:U11>0.4966</PDBx:U11>
         <PDBx:U12>-0.0274</PDBx:U12>
         <PDBx:U13>0.0598</PDBx:U13>
         <PDBx:U22>0.4279</PDBx:U22>
         <PDBx:U23>-0.0949</PDBx:U23>
         <PDBx:U33>0.3183</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="358">
         <PDBx:U11>0.4594</PDBx:U11>
         <PDBx:U12>-0.0416</PDBx:U12>
         <PDBx:U13>0.0682</PDBx:U13>
         <PDBx:U22>0.4112</PDBx:U22>
         <PDBx:U23>-0.0814</PDBx:U23>
         <PDBx:U33>0.2866</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="359">
         <PDBx:U11>0.4585</PDBx:U11>
         <PDBx:U12>-0.0797</PDBx:U12>
         <PDBx:U13>0.0650</PDBx:U13>
         <PDBx:U22>0.2860</PDBx:U22>
         <PDBx:U23>-0.0788</PDBx:U23>
         <PDBx:U33>0.3052</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="360">
         <PDBx:U11>0.4195</PDBx:U11>
         <PDBx:U12>-0.0825</PDBx:U12>
         <PDBx:U13>0.0648</PDBx:U13>
         <PDBx:U22>0.2362</PDBx:U22>
         <PDBx:U23>-0.0726</PDBx:U23>
         <PDBx:U33>0.2771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="361">
         <PDBx:U11>0.5142</PDBx:U11>
         <PDBx:U12>-0.0725</PDBx:U12>
         <PDBx:U13>0.0557</PDBx:U13>
         <PDBx:U22>0.3131</PDBx:U22>
         <PDBx:U23>-0.0769</PDBx:U23>
         <PDBx:U33>0.3650</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="362">
         <PDBx:U11>0.4950</PDBx:U11>
         <PDBx:U12>-0.0663</PDBx:U12>
         <PDBx:U13>0.0486</PDBx:U13>
         <PDBx:U22>0.2843</PDBx:U22>
         <PDBx:U23>-0.0751</PDBx:U23>
         <PDBx:U33>0.3627</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="363">
         <PDBx:U11>0.4354</PDBx:U11>
         <PDBx:U12>-0.1003</PDBx:U12>
         <PDBx:U13>0.0771</PDBx:U13>
         <PDBx:U22>0.2585</PDBx:U22>
         <PDBx:U23>-0.0666</PDBx:U23>
         <PDBx:U33>0.2846</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="364">
         <PDBx:U11>0.4193</PDBx:U11>
         <PDBx:U12>-0.1012</PDBx:U12>
         <PDBx:U13>0.0786</PDBx:U13>
         <PDBx:U22>0.2361</PDBx:U22>
         <PDBx:U23>-0.0620</PDBx:U23>
         <PDBx:U33>0.2747</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="365">
         <PDBx:U11>0.4604</PDBx:U11>
         <PDBx:U12>-0.1203</PDBx:U12>
         <PDBx:U13>0.0918</PDBx:U13>
         <PDBx:U22>0.2828</PDBx:U22>
         <PDBx:U23>-0.0607</PDBx:U23>
         <PDBx:U33>0.2938</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="366">
         <PDBx:U11>0.3739</PDBx:U11>
         <PDBx:U12>-0.1245</PDBx:U12>
         <PDBx:U13>0.1010</PDBx:U13>
         <PDBx:U22>0.2138</PDBx:U22>
         <PDBx:U23>-0.0625</PDBx:U23>
         <PDBx:U33>0.2124</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="367">
         <PDBx:U11>0.5353</PDBx:U11>
         <PDBx:U12>-0.0703</PDBx:U12>
         <PDBx:U13>0.0558</PDBx:U13>
         <PDBx:U22>0.3313</PDBx:U22>
         <PDBx:U23>-0.0827</PDBx:U23>
         <PDBx:U33>0.3607</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="368">
         <PDBx:U11>0.5766</PDBx:U11>
         <PDBx:U12>-0.0587</PDBx:U12>
         <PDBx:U13>0.0495</PDBx:U13>
         <PDBx:U22>0.3502</PDBx:U22>
         <PDBx:U23>-0.0873</PDBx:U23>
         <PDBx:U33>0.3903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="369">
         <PDBx:U11>0.5544</PDBx:U11>
         <PDBx:U12>-0.0373</PDBx:U12>
         <PDBx:U13>0.0370</PDBx:U13>
         <PDBx:U22>0.3192</PDBx:U22>
         <PDBx:U23>-0.0949</PDBx:U23>
         <PDBx:U33>0.3869</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="370">
         <PDBx:U11>0.5692</PDBx:U11>
         <PDBx:U12>-0.0313</PDBx:U12>
         <PDBx:U13>0.0300</PDBx:U13>
         <PDBx:U22>0.3139</PDBx:U22>
         <PDBx:U23>-0.0947</PDBx:U23>
         <PDBx:U33>0.4135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="371">
         <PDBx:U11>0.6011</PDBx:U11>
         <PDBx:U12>-0.0500</PDBx:U12>
         <PDBx:U13>0.0490</PDBx:U13>
         <PDBx:U22>0.3988</PDBx:U22>
         <PDBx:U23>-0.0835</PDBx:U23>
         <PDBx:U33>0.3952</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="372">
         <PDBx:U11>0.6102</PDBx:U11>
         <PDBx:U12>-0.0722</PDBx:U12>
         <PDBx:U13>0.0561</PDBx:U13>
         <PDBx:U22>0.4312</PDBx:U22>
         <PDBx:U23>-0.0712</PDBx:U23>
         <PDBx:U33>0.3953</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="373">
         <PDBx:U11>0.6713</PDBx:U11>
         <PDBx:U12>-0.0291</PDBx:U12>
         <PDBx:U13>0.0402</PDBx:U13>
         <PDBx:U22>0.4577</PDBx:U22>
         <PDBx:U23>-0.0806</PDBx:U23>
         <PDBx:U33>0.4690</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="374">
         <PDBx:U11>0.6578</PDBx:U11>
         <PDBx:U12>-0.0642</PDBx:U12>
         <PDBx:U13>0.0531</PDBx:U13>
         <PDBx:U22>0.5220</PDBx:U22>
         <PDBx:U23>-0.0594</PDBx:U23>
         <PDBx:U33>0.4360</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="375">
         <PDBx:U11>0.5594</PDBx:U11>
         <PDBx:U12>-0.0275</PDBx:U12>
         <PDBx:U13>0.0337</PDBx:U13>
         <PDBx:U22>0.3413</PDBx:U22>
         <PDBx:U23>-0.1020</PDBx:U23>
         <PDBx:U33>0.3953</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="376">
         <PDBx:U11>0.5445</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>0.0216</PDBx:U13>
         <PDBx:U22>0.3241</PDBx:U22>
         <PDBx:U23>-0.1126</PDBx:U23>
         <PDBx:U33>0.3970</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="377">
         <PDBx:U11>0.5490</PDBx:U11>
         <PDBx:U12>-0.0175</PDBx:U12>
         <PDBx:U13>0.0149</PDBx:U13>
         <PDBx:U22>0.3288</PDBx:U22>
         <PDBx:U23>-0.1082</PDBx:U23>
         <PDBx:U33>0.4328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="378">
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="411">
         <PDBx:U11>0.5021</PDBx:U11>
         <PDBx:U12>-0.0171</PDBx:U12>
         <PDBx:U13>-0.0109</PDBx:U13>
         <PDBx:U22>0.2529</PDBx:U22>
         <PDBx:U23>-0.1051</PDBx:U23>
         <PDBx:U33>0.4774</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="412">
         <PDBx:U11>0.5133</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>-0.0132</PDBx:U13>
         <PDBx:U22>0.2687</PDBx:U22>
         <PDBx:U23>-0.1093</PDBx:U23>
         <PDBx:U33>0.5067</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="413">
         <PDBx:U11>0.5659</PDBx:U11>
         <PDBx:U12>-0.0277</PDBx:U12>
         <PDBx:U13>-0.0200</PDBx:U13>
         <PDBx:U22>0.3104</PDBx:U22>
         <PDBx:U23>-0.0944</PDBx:U23>
         <PDBx:U33>0.5651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="414">
         <PDBx:U11>0.5503</PDBx:U11>
         <PDBx:U12>-0.0295</PDBx:U12>
         <PDBx:U13>-0.0243</PDBx:U13>
         <PDBx:U22>0.2964</PDBx:U22>
         <PDBx:U23>-0.0959</PDBx:U23>
         <PDBx:U33>0.5657</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="415">
         <PDBx:U11>0.5095</PDBx:U11>
         <PDBx:U12>-0.0159</PDBx:U12>
         <PDBx:U13>-0.0133</PDBx:U13>
         <PDBx:U22>0.2811</PDBx:U22>
         <PDBx:U23>-0.1167</PDBx:U23>
         <PDBx:U33>0.4929</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="416">
         <PDBx:U11>0.6074</PDBx:U11>
         <PDBx:U12>-0.0116</PDBx:U12>
         <PDBx:U13>0.0006</PDBx:U13>
         <PDBx:U22>0.3822</PDBx:U22>
         <PDBx:U23>-0.1328</PDBx:U23>
         <PDBx:U33>0.5746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="417">
         <PDBx:U11>0.7554</PDBx:U11>
         <PDBx:U12>-0.0164</PDBx:U12>
         <PDBx:U13>0.0073</PDBx:U13>
         <PDBx:U22>0.5235</PDBx:U22>
         <PDBx:U23>-0.1401</PDBx:U23>
         <PDBx:U33>0.7045</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="418">
         <PDBx:U11>0.8521</PDBx:U11>
         <PDBx:U12>-0.0141</PDBx:U12>
         <PDBx:U13>0.0036</PDBx:U13>
         <PDBx:U22>0.6432</PDBx:U22>
         <PDBx:U23>-0.1426</PDBx:U23>
         <PDBx:U33>0.7965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="419">
         <PDBx:U11>0.9466</PDBx:U11>
         <PDBx:U12>-0.0196</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.7365</PDBx:U22>
         <PDBx:U23>-0.1449</PDBx:U23>
         <PDBx:U33>0.8809</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="420">
         <PDBx:U11>0.9954</PDBx:U11>
         <PDBx:U12>-0.0262</PDBx:U12>
         <PDBx:U13>0.0033</PDBx:U13>
         <PDBx:U22>0.7612</PDBx:U22>
         <PDBx:U23>-0.1456</PDBx:U23>
         <PDBx:U33>0.9207</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="421">
         <PDBx:U11>0.9533</PDBx:U11>
         <PDBx:U12>-0.0159</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.7627</PDBx:U22>
         <PDBx:U23>-0.1468</PDBx:U23>
         <PDBx:U33>0.8829</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="422">
         <PDBx:U11>0.5247</PDBx:U11>
         <PDBx:U12>-0.0733</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.2777</PDBx:U22>
         <PDBx:U23>-0.0768</PDBx:U23>
         <PDBx:U33>0.3985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="423">
         <PDBx:U11>0.5195</PDBx:U11>
         <PDBx:U12>-0.0850</PDBx:U12>
         <PDBx:U13>-0.0128</PDBx:U13>
         <PDBx:U22>0.2863</PDBx:U22>
         <PDBx:U23>-0.0623</PDBx:U23>
         <PDBx:U33>0.3959</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="424">
         <PDBx:U11>0.5631</PDBx:U11>
         <PDBx:U12>-0.0927</PDBx:U12>
         <PDBx:U13>-0.0188</PDBx:U13>
         <PDBx:U22>0.3084</PDBx:U22>
         <PDBx:U23>-0.0636</PDBx:U23>
         <PDBx:U33>0.4534</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="425">
         <PDBx:U11>0.5677</PDBx:U11>
         <PDBx:U12>-0.0853</PDBx:U12>
         <PDBx:U13>-0.0166</PDBx:U13>
         <PDBx:U22>0.2939</PDBx:U22>
         <PDBx:U23>-0.0610</PDBx:U23>
         <PDBx:U33>0.4797</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="426">
         <PDBx:U11>0.4935</PDBx:U11>
         <PDBx:U12>-0.0800</PDBx:U12>
         <PDBx:U13>-0.0129</PDBx:U13>
         <PDBx:U22>0.2795</PDBx:U22>
         <PDBx:U23>-0.0449</PDBx:U23>
         <PDBx:U33>0.3832</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="427">
         <PDBx:U11>0.4862</PDBx:U11>
         <PDBx:U12>-0.0910</PDBx:U12>
         <PDBx:U13>-0.0224</PDBx:U13>
         <PDBx:U22>0.2866</PDBx:U22>
         <PDBx:U23>-0.0310</PDBx:U23>
         <PDBx:U33>0.3783</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="428">
         <PDBx:U11>0.4418</PDBx:U11>
         <PDBx:U12>-0.0749</PDBx:U12>
         <PDBx:U13>-0.0061</PDBx:U13>
         <PDBx:U22>0.2451</PDBx:U22>
         <PDBx:U23>-0.0434</PDBx:U23>
         <PDBx:U33>0.3178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="429">
         <PDBx:U11>0.5446</PDBx:U11>
         <PDBx:U12>-0.1087</PDBx:U12>
         <PDBx:U13>-0.0259</PDBx:U13>
         <PDBx:U22>0.2914</PDBx:U22>
         <PDBx:U23>-0.0669</PDBx:U23>
         <PDBx:U33>0.4223</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="430">
         <PDBx:U11>0.6516</PDBx:U11>
         <PDBx:U12>-0.1197</PDBx:U12>
         <PDBx:U13>-0.0306</PDBx:U13>
         <PDBx:U22>0.3745</PDBx:U22>
         <PDBx:U23>-0.0698</PDBx:U23>
         <PDBx:U33>0.5402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="431">
         <PDBx:U11>0.5764</PDBx:U11>
         <PDBx:U12>-0.1174</PDBx:U12>
         <PDBx:U13>-0.0313</PDBx:U13>
         <PDBx:U22>0.2940</PDBx:U22>
         <PDBx:U23>-0.0516</PDBx:U23>
         <PDBx:U33>0.4895</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="432">
         <PDBx:U11>0.5508</PDBx:U11>
         <PDBx:U12>-0.1180</PDBx:U12>
         <PDBx:U13>-0.0345</PDBx:U13>
         <PDBx:U22>0.2957</PDBx:U22>
         <PDBx:U23>-0.0345</PDBx:U23>
         <PDBx:U33>0.4648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="433">
         <PDBx:U11>0.7053</PDBx:U11>
         <PDBx:U12>-0.1395</PDBx:U12>
         <PDBx:U13>-0.0396</PDBx:U13>
         <PDBx:U22>0.4475</PDBx:U22>
         <PDBx:U23>-0.0685</PDBx:U23>
         <PDBx:U33>0.5760</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="434">
         <PDBx:U11>0.6396</PDBx:U11>
         <PDBx:U12>-0.1370</PDBx:U12>
         <PDBx:U13>-0.0378</PDBx:U13>
         <PDBx:U22>0.4034</PDBx:U22>
         <PDBx:U23>-0.0745</PDBx:U23>
         <PDBx:U33>0.4866</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="435">
         <PDBx:U11>0.5390</PDBx:U11>
         <PDBx:U12>-0.1186</PDBx:U12>
         <PDBx:U13>-0.0299</PDBx:U13>
         <PDBx:U22>0.3106</PDBx:U22>
         <PDBx:U23>-0.0667</PDBx:U23>
         <PDBx:U33>0.3920</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="436">
         <PDBx:U11>0.5568</PDBx:U11>
         <PDBx:U12>-0.1143</PDBx:U12>
         <PDBx:U13>-0.0277</PDBx:U13>
         <PDBx:U22>0.2386</PDBx:U22>
         <PDBx:U23>-0.0549</PDBx:U23>
         <PDBx:U33>0.4885</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="437">
         <PDBx:U11>0.5416</PDBx:U11>
         <PDBx:U12>-0.1127</PDBx:U12>
         <PDBx:U13>-0.0266</PDBx:U13>
         <PDBx:U22>0.2142</PDBx:U22>
         <PDBx:U23>-0.0352</PDBx:U23>
         <PDBx:U33>0.4941</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="438">
         <PDBx:U11>0.5540</PDBx:U11>
         <PDBx:U12>-0.0928</PDBx:U12>
         <PDBx:U13>-0.0191</PDBx:U13>
         <PDBx:U22>0.2225</PDBx:U22>
         <PDBx:U23>-0.0274</PDBx:U23>
         <PDBx:U33>0.5221</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="439">
         <PDBx:U11>0.5932</PDBx:U11>
         <PDBx:U12>-0.0872</PDBx:U12>
         <PDBx:U13>-0.0146</PDBx:U13>
         <PDBx:U22>0.2384</PDBx:U22>
         <PDBx:U23>-0.0143</PDBx:U23>
         <PDBx:U33>0.5778</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="440">
         <PDBx:U11>0.5598</PDBx:U11>
         <PDBx:U12>-0.0827</PDBx:U12>
         <PDBx:U13>-0.0171</PDBx:U13>
         <PDBx:U22>0.2494</PDBx:U22>
         <PDBx:U23>-0.0338</PDBx:U23>
         <PDBx:U33>0.5202</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="441">
         <PDBx:U11>0.5234</PDBx:U11>
         <PDBx:U12>-0.0658</PDBx:U12>
         <PDBx:U13>-0.0113</PDBx:U13>
         <PDBx:U22>0.2132</PDBx:U22>
         <PDBx:U23>-0.0274</PDBx:U23>
         <PDBx:U33>0.4969</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="442">
         <PDBx:U11>0.5768</PDBx:U11>
         <PDBx:U12>-0.0510</PDBx:U12>
         <PDBx:U13>-0.0059</PDBx:U13>
         <PDBx:U22>0.2267</PDBx:U22>
         <PDBx:U23>-0.0354</PDBx:U23>
         <PDBx:U33>0.5681</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="443">
         <PDBx:U11>0.6350</PDBx:U11>
         <PDBx:U12>-0.0382</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.2737</PDBx:U22>
         <PDBx:U23>-0.0205</PDBx:U23>
         <PDBx:U33>0.6429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="444">
         <PDBx:U11>0.4937</PDBx:U11>
         <PDBx:U12>-0.0603</PDBx:U12>
         <PDBx:U13>-0.0095</PDBx:U13>
         <PDBx:U22>0.2101</PDBx:U22>
         <PDBx:U23>-0.0356</PDBx:U23>
         <PDBx:U33>0.4527</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="445">
         <PDBx:U11>0.4992</PDBx:U11>
         <PDBx:U12>-0.0478</PDBx:U12>
         <PDBx:U13>-0.0055</PDBx:U13>
         <PDBx:U22>0.2223</PDBx:U22>
         <PDBx:U23>-0.0273</PDBx:U23>
         <PDBx:U33>0.4686</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="446">
         <PDBx:U11>0.4955</PDBx:U11>
         <PDBx:U12>-0.0521</PDBx:U12>
         <PDBx:U13>-0.0088</PDBx:U13>
         <PDBx:U22>0.2416</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.4680</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="447">
         <PDBx:U11>0.5045</PDBx:U11>
         <PDBx:U12>-0.0320</PDBx:U12>
         <PDBx:U13>0.0011</PDBx:U13>
         <PDBx:U22>0.2113</PDBx:U22>
         <PDBx:U23>-0.0389</PDBx:U23>
         <PDBx:U33>0.4752</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="448">
         <PDBx:U11>0.5422</PDBx:U11>
         <PDBx:U12>-0.0438</PDBx:U12>
         <PDBx:U13>-0.0065</PDBx:U13>
         <PDBx:U22>0.2930</PDBx:U22>
         <PDBx:U23>-0.0015</PDBx:U23>
         <PDBx:U33>0.5213</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="449">
         <PDBx:U11>0.5347</PDBx:U11>
         <PDBx:U12>-0.0210</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.2465</PDBx:U22>
         <PDBx:U23>-0.0315</PDBx:U23>
         <PDBx:U33>0.5114</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="450">
         <PDBx:U11>0.5188</PDBx:U11>
         <PDBx:U12>-0.0284</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.2506</PDBx:U22>
         <PDBx:U23>-0.0123</PDBx:U23>
         <PDBx:U33>0.5011</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="451">
         <PDBx:U11>0.6623</PDBx:U11>
         <PDBx:U12>-0.0511</PDBx:U12>
         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.2913</PDBx:U22>
         <PDBx:U23>-0.0581</PDBx:U23>
         <PDBx:U33>0.6446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="452">
         <PDBx:U11>0.7439</PDBx:U11>
         <PDBx:U12>-0.0345</PDBx:U12>
         <PDBx:U13>-0.0059</PDBx:U13>
         <PDBx:U22>0.3319</PDBx:U22>
         <PDBx:U23>-0.0701</PDBx:U23>
         <PDBx:U33>0.7354</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="453">
         <PDBx:U11>0.7733</PDBx:U11>
         <PDBx:U12>-0.0342</PDBx:U12>
         <PDBx:U13>-0.0070</PDBx:U13>
         <PDBx:U22>0.3318</PDBx:U22>
         <PDBx:U23>-0.0545</PDBx:U23>
         <PDBx:U33>0.7883</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="454">
         <PDBx:U11>0.8544</PDBx:U11>
         <PDBx:U12>-0.0143</PDBx:U12>
         <PDBx:U13>-0.0114</PDBx:U13>
         <PDBx:U22>0.3801</PDBx:U22>
         <PDBx:U23>-0.0526</PDBx:U23>
         <PDBx:U33>0.8748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="455">
         <PDBx:U11>0.8128</PDBx:U11>
         <PDBx:U12>-0.0372</PDBx:U12>
         <PDBx:U13>-0.0044</PDBx:U13>
         <PDBx:U22>0.3849</PDBx:U22>
         <PDBx:U23>-0.0996</PDBx:U23>
         <PDBx:U33>0.7798</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="456">
         <PDBx:U11>0.8407</PDBx:U11>
         <PDBx:U12>-0.0619</PDBx:U12>
         <PDBx:U13>-0.0097</PDBx:U13>
         <PDBx:U22>0.4125</PDBx:U22>
         <PDBx:U23>-0.1038</PDBx:U23>
         <PDBx:U33>0.8001</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="457">
         <PDBx:U11>0.8885</PDBx:U11>
         <PDBx:U12>-0.0178</PDBx:U12>
         <PDBx:U13>-0.0019</PDBx:U13>
         <PDBx:U22>0.4136</PDBx:U22>
         <PDBx:U23>-0.1139</PDBx:U23>
         <PDBx:U33>0.8574</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="458">
         <PDBx:U11>0.7258</PDBx:U11>
         <PDBx:U12>-0.0550</PDBx:U12>
         <PDBx:U13>-0.0045</PDBx:U13>
         <PDBx:U22>0.2897</PDBx:U22>
         <PDBx:U23>-0.0426</PDBx:U23>
         <PDBx:U33>0.7430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="459">
         <PDBx:U11>0.7963</PDBx:U11>
         <PDBx:U12>-0.0585</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.3285</PDBx:U22>
         <PDBx:U23>-0.0264</PDBx:U23>
         <PDBx:U33>0.8275</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="460">
         <PDBx:U11>0.7717</PDBx:U11>
         <PDBx:U12>-0.0444</PDBx:U12>
         <PDBx:U13>0.0141</PDBx:U13>
         <PDBx:U22>0.2998</PDBx:U22>
         <PDBx:U23>0.0038</PDBx:U23>
         <PDBx:U33>0.7965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="461">
         <PDBx:U11>0.8424</PDBx:U11>
         <PDBx:U12>-0.0397</PDBx:U12>
         <PDBx:U13>0.0220</PDBx:U13>
         <PDBx:U22>0.3280</PDBx:U22>
         <PDBx:U23>0.0204</PDBx:U23>
         <PDBx:U33>0.8550</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="462">
         <PDBx:U11>0.8382</PDBx:U11>
         <PDBx:U12>-0.0862</PDBx:U12>
         <PDBx:U13>-0.0026</PDBx:U13>
         <PDBx:U22>0.3731</PDBx:U22>
         <PDBx:U23>-0.0230</PDBx:U23>
         <PDBx:U33>0.8580</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="463">
         <PDBx:U11>0.8568</PDBx:U11>
         <PDBx:U12>-0.1010</PDBx:U12>
         <PDBx:U13>-0.0115</PDBx:U13>
         <PDBx:U22>0.3879</PDBx:U22>
         <PDBx:U23>-0.0512</PDBx:U23>
         <PDBx:U33>0.8649</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="464">
         <PDBx:U11>0.8321</PDBx:U11>
         <PDBx:U12>-0.0943</PDBx:U12>
         <PDBx:U13>-0.0129</PDBx:U13>
         <PDBx:U22>0.3278</PDBx:U22>
         <PDBx:U23>-0.0718</PDBx:U23>
         <PDBx:U33>0.8443</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="465">
         <PDBx:U11>0.8719</PDBx:U11>
         <PDBx:U12>-0.1177</PDBx:U12>
         <PDBx:U13>-0.0186</PDBx:U13>
         <PDBx:U22>0.4366</PDBx:U22>
         <PDBx:U23>-0.0519</PDBx:U23>
         <PDBx:U33>0.8588</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="466">
         <PDBx:U11>0.6630</PDBx:U11>
         <PDBx:U12>-0.0375</PDBx:U12>
         <PDBx:U13>0.0116</PDBx:U13>
         <PDBx:U22>0.2236</PDBx:U22>
         <PDBx:U23>0.0111</PDBx:U23>
         <PDBx:U33>0.6758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="467">
         <PDBx:U11>0.6966</PDBx:U11>
         <PDBx:U12>-0.0243</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.2526</PDBx:U22>
         <PDBx:U23>0.0393</PDBx:U23>
         <PDBx:U33>0.6926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="468">
         <PDBx:U11>0.7539</PDBx:U11>
         <PDBx:U12>0.0065</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.2760</PDBx:U22>
         <PDBx:U23>0.0407</PDBx:U23>
         <PDBx:U33>0.7402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="469">
         <PDBx:U11>0.7959</PDBx:U11>
         <PDBx:U12>0.0175</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.3039</PDBx:U22>
         <PDBx:U23>0.0169</PDBx:U23>
         <PDBx:U33>0.7696</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="470">
         <PDBx:U11>0.6614</PDBx:U11>
         <PDBx:U12>-0.0301</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.2745</PDBx:U22>
         <PDBx:U23>0.0448</PDBx:U23>
         <PDBx:U33>0.6616</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="471">
         <PDBx:U11>0.6333</PDBx:U11>
         <PDBx:U12>-0.0542</PDBx:U12>
         <PDBx:U13>-0.0124</PDBx:U13>
         <PDBx:U22>0.2852</PDBx:U22>
         <PDBx:U23>0.0411</PDBx:U23>
         <PDBx:U33>0.6300</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="472">
         <PDBx:U11>0.5409</PDBx:U11>
         <PDBx:U12>-0.0557</PDBx:U12>
         <PDBx:U13>-0.0193</PDBx:U13>
         <PDBx:U22>0.2405</PDBx:U22>
         <PDBx:U23>0.0428</PDBx:U23>
         <PDBx:U33>0.5345</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="473">
         <PDBx:U11>0.6984</PDBx:U11>
         <PDBx:U12>-0.0669</PDBx:U12>
         <PDBx:U13>-0.0205</PDBx:U13>
         <PDBx:U22>0.3507</PDBx:U22>
         <PDBx:U23>0.0612</PDBx:U23>
         <PDBx:U33>0.6946</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="474">
         <PDBx:U11>0.7633</PDBx:U11>
         <PDBx:U12>0.0221</PDBx:U12>
         <PDBx:U13>-0.0065</PDBx:U13>
         <PDBx:U22>0.2868</PDBx:U22>
         <PDBx:U23>0.0692</PDBx:U23>
         <PDBx:U33>0.7699</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="475">
         <PDBx:U11>0.7489</PDBx:U11>
         <PDBx:U12>0.0561</PDBx:U12>
         <PDBx:U13>-0.0087</PDBx:U13>
         <PDBx:U22>0.2704</PDBx:U22>
         <PDBx:U23>0.0747</PDBx:U23>
         <PDBx:U33>0.7819</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.7040</PDBx:U11>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:U33>0.6265</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="493">
         <PDBx:U11>0.8347</PDBx:U11>
         <PDBx:U12>0.1160</PDBx:U12>
         <PDBx:U13>-0.0332</PDBx:U13>
         <PDBx:U22>0.6207</PDBx:U22>
         <PDBx:U23>0.1731</PDBx:U23>
         <PDBx:U33>1.0223</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="494">
         <PDBx:U11>0.9574</PDBx:U11>
         <PDBx:U12>0.1534</PDBx:U12>
         <PDBx:U13>-0.0251</PDBx:U13>
         <PDBx:U22>0.7439</PDBx:U22>
         <PDBx:U23>0.1765</PDBx:U23>
         <PDBx:U33>1.1726</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="495">
         <PDBx:U11>0.9684</PDBx:U11>
         <PDBx:U12>0.1750</PDBx:U12>
         <PDBx:U13>-0.0183</PDBx:U13>
         <PDBx:U22>0.8126</PDBx:U22>
         <PDBx:U23>0.1749</PDBx:U23>
         <PDBx:U33>1.2179</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="496">
         <PDBx:U11>1.0576</PDBx:U11>
         <PDBx:U12>0.1731</PDBx:U12>
         <PDBx:U13>-0.0226</PDBx:U13>
         <PDBx:U22>0.7965</PDBx:U22>
         <PDBx:U23>0.1810</PDBx:U23>
         <PDBx:U33>1.2710</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="497">
         <PDBx:U11>1.0356</PDBx:U11>
         <PDBx:U12>0.2068</PDBx:U12>
         <PDBx:U13>-0.0119</PDBx:U13>
         <PDBx:U22>0.8712</PDBx:U22>
         <PDBx:U23>0.1775</PDBx:U23>
         <PDBx:U33>1.3034</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="498">
         <PDBx:U11>1.0894</PDBx:U11>
         <PDBx:U12>0.2072</PDBx:U12>
         <PDBx:U13>-0.0149</PDBx:U13>
         <PDBx:U22>0.8578</PDBx:U22>
         <PDBx:U23>0.1817</PDBx:U23>
         <PDBx:U33>1.3360</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="499">
         <PDBx:U11>0.6053</PDBx:U11>
         <PDBx:U12>0.0469</PDBx:U12>
         <PDBx:U13>-0.0334</PDBx:U13>
         <PDBx:U22>0.3362</PDBx:U22>
         <PDBx:U23>0.1286</PDBx:U23>
         <PDBx:U33>0.7163</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="500">
         <PDBx:U11>0.5494</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>-0.0400</PDBx:U13>
         <PDBx:U22>0.2924</PDBx:U22>
         <PDBx:U23>0.1243</PDBx:U23>
         <PDBx:U33>0.6334</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="501">
         <PDBx:U11>0.5340</PDBx:U11>
         <PDBx:U12>0.0038</PDBx:U12>
         <PDBx:U13>-0.0334</PDBx:U13>
         <PDBx:U22>0.2811</PDBx:U22>
         <PDBx:U23>0.0966</PDBx:U23>
         <PDBx:U33>0.6047</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="502">
         <PDBx:U11>0.4932</PDBx:U11>
         <PDBx:U12>-0.0150</PDBx:U12>
         <PDBx:U13>-0.0374</PDBx:U13>
         <PDBx:U22>0.2777</PDBx:U22>
         <PDBx:U23>0.0940</PDBx:U23>
         <PDBx:U33>0.5502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="503">
         <PDBx:U11>0.6206</PDBx:U11>
         <PDBx:U12>0.0007</PDBx:U12>
         <PDBx:U13>-0.0381</PDBx:U13>
         <PDBx:U22>0.3220</PDBx:U22>
         <PDBx:U23>0.1199</PDBx:U23>
         <PDBx:U33>0.6772</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="504">
         <PDBx:U11>0.6936</PDBx:U11>
         <PDBx:U12>0.0033</PDBx:U12>
         <PDBx:U13>-0.0462</PDBx:U13>
         <PDBx:U22>0.3980</PDBx:U22>
         <PDBx:U23>0.1501</PDBx:U23>
         <PDBx:U33>0.7587</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="505">
         <PDBx:U11>0.6771</PDBx:U11>
         <PDBx:U12>0.0204</PDBx:U12>
         <PDBx:U13>-0.0527</PDBx:U13>
         <PDBx:U22>0.4132</PDBx:U22>
         <PDBx:U23>0.1735</PDBx:U23>
         <PDBx:U33>0.7678</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="506">
         <PDBx:U11>0.6962</PDBx:U11>
         <PDBx:U12>-0.0118</PDBx:U12>
         <PDBx:U13>-0.0454</PDBx:U13>
         <PDBx:U22>0.3758</PDBx:U22>
         <PDBx:U23>0.1514</PDBx:U23>
         <PDBx:U33>0.7442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="507">
         <PDBx:U11>0.5390</PDBx:U11>
         <PDBx:U12>0.0167</PDBx:U12>
         <PDBx:U13>-0.0199</PDBx:U13>
         <PDBx:U22>0.2544</PDBx:U22>
         <PDBx:U23>0.0717</PDBx:U23>
         <PDBx:U33>0.6071</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="508">
         <PDBx:U11>0.4248</PDBx:U11>
         <PDBx:U12>0.0085</PDBx:U12>
         <PDBx:U13>-0.0100</PDBx:U13>
         <PDBx:U22>0.1520</PDBx:U22>
         <PDBx:U23>0.0430</PDBx:U23>
         <PDBx:U33>0.4733</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="509">
         <PDBx:U11>0.3798</PDBx:U11>
         <PDBx:U12>0.0122</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.1709</PDBx:U22>
         <PDBx:U23>0.0438</PDBx:U23>
         <PDBx:U33>0.4414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="510">
         <PDBx:U11>0.4023</PDBx:U11>
         <PDBx:U12>-0.0044</PDBx:U12>
         <PDBx:U13>-0.0057</PDBx:U13>
         <PDBx:U22>0.2183</PDBx:U22>
         <PDBx:U23>0.0346</PDBx:U23>
         <PDBx:U33>0.4474</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="511">
         <PDBx:U11>0.4900</PDBx:U11>
         <PDBx:U12>0.0223</PDBx:U12>
         <PDBx:U13>0.0047</PDBx:U13>
         <PDBx:U22>0.1735</PDBx:U22>
         <PDBx:U23>0.0170</PDBx:U23>
         <PDBx:U33>0.5319</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="512">
         <PDBx:U11>0.5228</PDBx:U11>
         <PDBx:U12>0.0119</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.1593</PDBx:U22>
         <PDBx:U23>0.0074</PDBx:U23>
         <PDBx:U33>0.5274</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="513">
         <PDBx:U11>0.6542</PDBx:U11>
         <PDBx:U12>0.0233</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.2689</PDBx:U22>
         <PDBx:U23>-0.0204</PDBx:U23>
         <PDBx:U33>0.6568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="514">
         <PDBx:U11>0.6368</PDBx:U11>
         <PDBx:U12>0.0434</PDBx:U12>
         <PDBx:U13>0.0202</PDBx:U13>
         <PDBx:U22>0.2630</PDBx:U22>
         <PDBx:U23>-0.0307</PDBx:U23>
         <PDBx:U33>0.6528</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="515">
         <PDBx:U11>0.7308</PDBx:U11>
         <PDBx:U12>0.0099</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.3296</PDBx:U22>
         <PDBx:U23>-0.0329</PDBx:U23>
         <PDBx:U33>0.7306</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="516">
         <PDBx:U11>0.4107</PDBx:U11>
         <PDBx:U12>0.0339</PDBx:U12>
         <PDBx:U13>-0.0046</PDBx:U13>
         <PDBx:U22>0.2278</PDBx:U22>
         <PDBx:U23>0.0552</PDBx:U23>
         <PDBx:U33>0.5029</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="517">
         <PDBx:U11>0.3588</PDBx:U11>
         <PDBx:U12>0.0348</PDBx:U12>
         <PDBx:U13>-0.0027</PDBx:U13>
         <PDBx:U22>0.2416</PDBx:U22>
         <PDBx:U23>0.0569</PDBx:U23>
         <PDBx:U33>0.4671</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="518">
         <PDBx:U11>0.4461</PDBx:U11>
         <PDBx:U12>0.0120</PDBx:U12>
         <PDBx:U13>-0.0150</PDBx:U13>
         <PDBx:U22>0.3679</PDBx:U22>
         <PDBx:U23>0.0688</PDBx:U23>
         <PDBx:U33>0.5456</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="519">
         <PDBx:U11>0.3686</PDBx:U11>
         <PDBx:U12>-0.0022</PDBx:U12>
         <PDBx:U13>-0.0109</PDBx:U13>
         <PDBx:U22>0.3222</PDBx:U22>
         <PDBx:U23>0.0566</PDBx:U23>
         <PDBx:U33>0.4594</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="520">
         <PDBx:U11>0.4430</PDBx:U11>
         <PDBx:U12>0.0616</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
         <PDBx:U22>0.3571</PDBx:U22>
         <PDBx:U23>0.0744</PDBx:U23>
         <PDBx:U33>0.5900</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="521">
         <PDBx:U11>0.4019</PDBx:U11>
         <PDBx:U12>0.0548</PDBx:U12>
         <PDBx:U13>-0.0066</PDBx:U13>
         <PDBx:U22>0.3940</PDBx:U22>
         <PDBx:U23>0.0805</PDBx:U23>
         <PDBx:U33>0.5656</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="522">
         <PDBx:U11>0.4366</PDBx:U11>
         <PDBx:U12>0.0870</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.3248</PDBx:U22>
         <PDBx:U23>0.0577</PDBx:U23>
         <PDBx:U33>0.5955</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="523">
         <PDBx:U11>0.4519</PDBx:U11>
         <PDBx:U12>0.0084</PDBx:U12>
         <PDBx:U13>-0.0288</PDBx:U13>
         <PDBx:U22>0.3689</PDBx:U22>
         <PDBx:U23>0.0924</PDBx:U23>
         <PDBx:U33>0.5528</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="524">
         <PDBx:U11>0.3687</PDBx:U11>
         <PDBx:U12>-0.0111</PDBx:U12>
         <PDBx:U13>-0.0400</PDBx:U13>
         <PDBx:U22>0.3273</PDBx:U22>
         <PDBx:U23>0.1048</PDBx:U23>
         <PDBx:U33>0.4618</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="525">
         <PDBx:U11>0.4160</PDBx:U11>
         <PDBx:U12>-0.0337</PDBx:U12>
         <PDBx:U13>-0.0370</PDBx:U13>
         <PDBx:U22>0.3649</PDBx:U22>
         <PDBx:U23>0.0867</PDBx:U23>
         <PDBx:U33>0.4788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="526">
         <PDBx:U11>0.3456</PDBx:U11>
         <PDBx:U12>-0.0472</PDBx:U12>
         <PDBx:U13>-0.0370</PDBx:U13>
         <PDBx:U22>0.3332</PDBx:U22>
         <PDBx:U23>0.0808</PDBx:U23>
         <PDBx:U33>0.4015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="527">
         <PDBx:U11>0.4791</PDBx:U11>
         <PDBx:U12>-0.0104</PDBx:U12>
         <PDBx:U13>-0.0539</PDBx:U13>
         <PDBx:U22>0.4319</PDBx:U22>
         <PDBx:U23>0.1359</PDBx:U23>
         <PDBx:U33>0.5777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="528">
         <PDBx:U11>0.5622</PDBx:U11>
         <PDBx:U12>-0.0306</PDBx:U12>
         <PDBx:U13>-0.0644</PDBx:U13>
         <PDBx:U22>0.5600</PDBx:U22>
         <PDBx:U23>0.1483</PDBx:U23>
         <PDBx:U33>0.6499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="529">
         <PDBx:U11>0.5627</PDBx:U11>
         <PDBx:U12>-0.0506</PDBx:U12>
         <PDBx:U13>-0.0676</PDBx:U13>
         <PDBx:U22>0.5447</PDBx:U22>
         <PDBx:U23>0.1472</PDBx:U23>
         <PDBx:U33>0.6265</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="530">
         <PDBx:U11>0.5831</PDBx:U11>
         <PDBx:U12>-0.0344</PDBx:U12>
         <PDBx:U13>-0.0718</PDBx:U13>
         <PDBx:U22>0.6457</PDBx:U22>
         <PDBx:U23>0.1601</PDBx:U23>
         <PDBx:U33>0.6798</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="531">
         <PDBx:U11>0.5277</PDBx:U11>
         <PDBx:U12>-0.0640</PDBx:U12>
         <PDBx:U13>-0.0749</PDBx:U13>
         <PDBx:U22>0.5604</PDBx:U22>
         <PDBx:U23>0.1573</PDBx:U23>
         <PDBx:U33>0.5860</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="532">
         <PDBx:U11>0.5806</PDBx:U11>
         <PDBx:U12>-0.0557</PDBx:U12>
         <PDBx:U13>-0.0780</PDBx:U13>
         <PDBx:U22>0.6616</PDBx:U22>
         <PDBx:U23>0.1644</PDBx:U23>
         <PDBx:U33>0.6567</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="533">
         <PDBx:U11>0.3948</PDBx:U11>
         <PDBx:U12>-0.0375</PDBx:U12>
         <PDBx:U13>-0.0344</PDBx:U13>
         <PDBx:U22>0.2927</PDBx:U22>
         <PDBx:U23>0.0776</PDBx:U23>
         <PDBx:U33>0.4397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="534">
         <PDBx:U11>0.3792</PDBx:U11>
         <PDBx:U12>-0.0553</PDBx:U12>
         <PDBx:U13>-0.0321</PDBx:U13>
         <PDBx:U22>0.2701</PDBx:U22>
         <PDBx:U23>0.0632</PDBx:U23>
         <PDBx:U33>0.3977</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="535">
         <PDBx:U11>0.3188</PDBx:U11>
         <PDBx:U12>-0.0560</PDBx:U12>
         <PDBx:U13>-0.0196</PDBx:U13>
         <PDBx:U22>0.2238</PDBx:U22>
         <PDBx:U23>0.0417</PDBx:U23>
         <PDBx:U33>0.3303</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="536">
         <PDBx:U11>0.2948</PDBx:U11>
         <PDBx:U12>-0.0683</PDBx:U12>
         <PDBx:U13>-0.0182</PDBx:U13>
         <PDBx:U22>0.2209</PDBx:U22>
         <PDBx:U23>0.0361</PDBx:U23>
         <PDBx:U33>0.2942</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="537">
         <PDBx:U11>0.4126</PDBx:U11>
         <PDBx:U12>-0.0596</PDBx:U12>
         <PDBx:U13>-0.0324</PDBx:U13>
         <PDBx:U22>0.2522</PDBx:U22>
         <PDBx:U23>0.0569</PDBx:U23>
         <PDBx:U33>0.4152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="538">
         <PDBx:U11>0.4187</PDBx:U11>
         <PDBx:U12>-0.0634</PDBx:U12>
         <PDBx:U13>-0.0409</PDBx:U13>
         <PDBx:U22>0.2489</PDBx:U22>
         <PDBx:U23>0.0730</PDBx:U23>
         <PDBx:U33>0.4225</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="539">
         <PDBx:U11>0.4362</PDBx:U11>
         <PDBx:U12>-0.0666</PDBx:U12>
         <PDBx:U13>-0.0346</PDBx:U13>
         <PDBx:U22>0.2410</PDBx:U22>
         <PDBx:U23>0.0564</PDBx:U23>
         <PDBx:U33>0.4251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="540">
         <PDBx:U11>0.3909</PDBx:U11>
         <PDBx:U12>-0.0757</PDBx:U12>
         <PDBx:U13>-0.0493</PDBx:U13>
         <PDBx:U22>0.2648</PDBx:U22>
         <PDBx:U23>0.0865</PDBx:U23>
         <PDBx:U33>0.3920</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="541">
         <PDBx:U11>0.2862</PDBx:U11>
         <PDBx:U12>-0.0425</PDBx:U12>
         <PDBx:U13>-0.0093</PDBx:U13>
         <PDBx:U22>0.1776</PDBx:U22>
         <PDBx:U23>0.0299</PDBx:U23>
         <PDBx:U33>0.3049</PDBx:U33>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="574">
         <PDBx:U11>0.3264</PDBx:U11>
         <PDBx:U12>-0.0961</PDBx:U12>
         <PDBx:U13>0.0424</PDBx:U13>
         <PDBx:U22>0.3265</PDBx:U22>
         <PDBx:U23>-0.0284</PDBx:U23>
         <PDBx:U33>0.3289</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="575">
         <PDBx:U11>0.2784</PDBx:U11>
         <PDBx:U12>-0.0969</PDBx:U12>
         <PDBx:U13>0.0295</PDBx:U13>
         <PDBx:U22>0.3150</PDBx:U22>
         <PDBx:U23>-0.0188</PDBx:U23>
         <PDBx:U33>0.2989</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="576">
         <PDBx:U11>0.2908</PDBx:U11>
         <PDBx:U12>-0.1089</PDBx:U12>
         <PDBx:U13>0.0539</PDBx:U13>
         <PDBx:U22>0.3021</PDBx:U22>
         <PDBx:U23>-0.0391</PDBx:U23>
         <PDBx:U33>0.2920</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="577">
         <PDBx:U11>0.2999</PDBx:U11>
         <PDBx:U12>-0.1124</PDBx:U12>
         <PDBx:U13>0.0322</PDBx:U13>
         <PDBx:U22>0.3749</PDBx:U22>
         <PDBx:U23>-0.0254</PDBx:U23>
         <PDBx:U33>0.3303</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="578">
         <PDBx:U11>0.3203</PDBx:U11>
         <PDBx:U12>-0.1172</PDBx:U12>
         <PDBx:U13>0.0463</PDBx:U13>
         <PDBx:U22>0.3754</PDBx:U22>
         <PDBx:U23>-0.0382</PDBx:U23>
         <PDBx:U33>0.3378</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="579">
         <PDBx:U11>0.3370</PDBx:U11>
         <PDBx:U12>-0.1072</PDBx:U12>
         <PDBx:U13>0.0661</PDBx:U13>
         <PDBx:U22>0.3246</PDBx:U22>
         <PDBx:U23>-0.0466</PDBx:U23>
         <PDBx:U33>0.3211</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="580">
         <PDBx:U11>0.3504</PDBx:U11>
         <PDBx:U12>-0.1255</PDBx:U12>
         <PDBx:U13>0.0511</PDBx:U13>
         <PDBx:U22>0.4190</PDBx:U22>
         <PDBx:U23>-0.0473</PDBx:U23>
         <PDBx:U33>0.3655</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="581">
         <PDBx:U11>0.3467</PDBx:U11>
         <PDBx:U12>-0.1161</PDBx:U12>
         <PDBx:U13>0.0712</PDBx:U13>
         <PDBx:U22>0.3476</PDBx:U22>
         <PDBx:U23>-0.0537</PDBx:U23>
         <PDBx:U33>0.3312</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="582">
         <PDBx:U11>0.3429</PDBx:U11>
         <PDBx:U12>-0.1259</PDBx:U12>
         <PDBx:U13>0.0640</PDBx:U13>
         <PDBx:U22>0.3815</PDBx:U22>
         <PDBx:U23>-0.0553</PDBx:U23>
         <PDBx:U33>0.3421</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="583">
         <PDBx:U11>0.3245</PDBx:U11>
         <PDBx:U12>-0.0925</PDBx:U12>
         <PDBx:U13>0.0414</PDBx:U13>
         <PDBx:U22>0.2822</PDBx:U22>
         <PDBx:U23>-0.0321</PDBx:U23>
         <PDBx:U33>0.2761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="584">
         <PDBx:U11>0.3301</PDBx:U11>
         <PDBx:U12>-0.0931</PDBx:U12>
         <PDBx:U13>0.0502</PDBx:U13>
         <PDBx:U22>0.2799</PDBx:U22>
         <PDBx:U23>-0.0389</PDBx:U23>
         <PDBx:U33>0.2674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="585">
         <PDBx:U11>0.3307</PDBx:U11>
         <PDBx:U12>-0.0856</PDBx:U12>
         <PDBx:U13>0.0489</PDBx:U13>
         <PDBx:U22>0.2647</PDBx:U22>
         <PDBx:U23>-0.0350</PDBx:U23>
         <PDBx:U33>0.2524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="586">
         <PDBx:U11>0.3580</PDBx:U11>
         <PDBx:U12>-0.0821</PDBx:U12>
         <PDBx:U13>0.0582</PDBx:U13>
         <PDBx:U22>0.2745</PDBx:U22>
         <PDBx:U23>-0.0368</PDBx:U23>
         <PDBx:U33>0.2673</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="587">
         <PDBx:U11>0.3063</PDBx:U11>
         <PDBx:U12>-0.1047</PDBx:U12>
         <PDBx:U13>0.0503</PDBx:U13>
         <PDBx:U22>0.2795</PDBx:U22>
         <PDBx:U23>-0.0458</PDBx:U23>
         <PDBx:U33>0.2487</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="588">
         <PDBx:U11>0.3539</PDBx:U11>
         <PDBx:U12>-0.1089</PDBx:U12>
         <PDBx:U13>0.0631</PDBx:U13>
         <PDBx:U22>0.3137</PDBx:U22>
         <PDBx:U23>-0.0551</PDBx:U23>
         <PDBx:U33>0.2832</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="589">
         <PDBx:U11>0.3776</PDBx:U11>
         <PDBx:U12>-0.1077</PDBx:U12>
         <PDBx:U13>0.0741</PDBx:U13>
         <PDBx:U22>0.3194</PDBx:U22>
         <PDBx:U23>-0.0573</PDBx:U23>
         <PDBx:U33>0.3040</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="590">
         <PDBx:U11>0.3294</PDBx:U11>
         <PDBx:U12>-0.1231</PDBx:U12>
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         <PDBx:U22>0.3139</PDBx:U22>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
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         <PDBx:U23>-0.0051</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
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         <PDBx:U23>0.0040</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
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         <PDBx:U23>-0.0189</PDBx:U23>
         <PDBx:U33>0.2035</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0226</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0207</PDBx:U23>
         <PDBx:U33>0.2650</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
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         <PDBx:U23>-0.0191</PDBx:U23>
         <PDBx:U33>0.2491</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0131</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="607">
         <PDBx:U11>0.3752</PDBx:U11>
         <PDBx:U12>-0.0641</PDBx:U12>
         <PDBx:U13>0.0155</PDBx:U13>
         <PDBx:U22>0.2590</PDBx:U22>
         <PDBx:U23>-0.0136</PDBx:U23>
         <PDBx:U33>0.2994</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="608">
         <PDBx:U11>0.3137</PDBx:U11>
         <PDBx:U12>-0.0675</PDBx:U12>
         <PDBx:U13>0.0596</PDBx:U13>
         <PDBx:U22>0.1999</PDBx:U22>
         <PDBx:U23>-0.0279</PDBx:U23>
         <PDBx:U33>0.2068</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="609">
         <PDBx:U11>0.3577</PDBx:U11>
         <PDBx:U12>-0.0685</PDBx:U12>
         <PDBx:U13>0.0731</PDBx:U13>
         <PDBx:U22>0.2307</PDBx:U22>
         <PDBx:U23>-0.0315</PDBx:U23>
         <PDBx:U33>0.2405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="610">
         <PDBx:U11>0.3566</PDBx:U11>
         <PDBx:U12>-0.0657</PDBx:U12>
         <PDBx:U13>0.0763</PDBx:U13>
         <PDBx:U22>0.2177</PDBx:U22>
         <PDBx:U23>-0.0301</PDBx:U23>
         <PDBx:U33>0.2292</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="611">
         <PDBx:U11>0.4000</PDBx:U11>
         <PDBx:U12>-0.0614</PDBx:U12>
         <PDBx:U13>0.0831</PDBx:U13>
         <PDBx:U22>0.2403</PDBx:U22>
         <PDBx:U23>-0.0281</PDBx:U23>
         <PDBx:U33>0.2584</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="612">
         <PDBx:U11>0.3567</PDBx:U11>
         <PDBx:U12>-0.0771</PDBx:U12>
         <PDBx:U13>0.0801</PDBx:U13>
         <PDBx:U22>0.2399</PDBx:U22>
         <PDBx:U23>-0.0389</PDBx:U23>
         <PDBx:U33>0.2523</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="613">
         <PDBx:U11>0.3466</PDBx:U11>
         <PDBx:U12>-0.0812</PDBx:U12>
         <PDBx:U13>0.0835</PDBx:U13>
         <PDBx:U22>0.2369</PDBx:U22>
         <PDBx:U23>-0.0425</PDBx:U23>
         <PDBx:U33>0.2530</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="614">
         <PDBx:U11>0.3930</PDBx:U11>
         <PDBx:U12>-0.0923</PDBx:U12>
         <PDBx:U13>0.0899</PDBx:U13>
         <PDBx:U22>0.2984</PDBx:U22>
         <PDBx:U23>-0.0500</PDBx:U23>
         <PDBx:U33>0.3138</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="615">
         <PDBx:U11>0.3701</PDBx:U11>
         <PDBx:U12>-0.0779</PDBx:U12>
         <PDBx:U13>0.0925</PDBx:U13>
         <PDBx:U22>0.2407</PDBx:U22>
         <PDBx:U23>-0.0426</PDBx:U23>
         <PDBx:U33>0.2599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="616">
         <PDBx:U11>0.3339</PDBx:U11>
         <PDBx:U12>-0.0682</PDBx:U12>
         <PDBx:U13>0.0723</PDBx:U13>
         <PDBx:U22>0.2052</PDBx:U22>
         <PDBx:U23>-0.0310</PDBx:U23>
         <PDBx:U33>0.2132</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="617">
         <PDBx:U11>0.3940</PDBx:U11>
         <PDBx:U12>-0.0668</PDBx:U12>
         <PDBx:U13>0.0793</PDBx:U13>
         <PDBx:U22>0.2511</PDBx:U22>
         <PDBx:U23>-0.0312</PDBx:U23>
         <PDBx:U33>0.2644</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="618">
         <PDBx:U11>0.3816</PDBx:U11>
         <PDBx:U12>-0.0575</PDBx:U12>
         <PDBx:U13>0.0768</PDBx:U13>
         <PDBx:U22>0.2220</PDBx:U22>
         <PDBx:U23>-0.0245</PDBx:U23>
         <PDBx:U33>0.2381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="619">
         <PDBx:U11>0.4249</PDBx:U11>
         <PDBx:U12>-0.0509</PDBx:U12>
         <PDBx:U13>0.0864</PDBx:U13>
         <PDBx:U22>0.2418</PDBx:U22>
         <PDBx:U23>-0.0214</PDBx:U23>
         <PDBx:U33>0.2704</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="620">
         <PDBx:U11>0.3966</PDBx:U11>
         <PDBx:U12>-0.0744</PDBx:U12>
         <PDBx:U13>0.0776</PDBx:U13>
         <PDBx:U22>0.2688</PDBx:U22>
         <PDBx:U23>-0.0360</PDBx:U23>
         <PDBx:U33>0.2752</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="621">
         <PDBx:U11>0.3555</PDBx:U11>
         <PDBx:U12>-0.0850</PDBx:U12>
         <PDBx:U13>0.0844</PDBx:U13>
         <PDBx:U22>0.2360</PDBx:U22>
         <PDBx:U23>-0.0449</PDBx:U23>
         <PDBx:U33>0.2421</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="622">
         <PDBx:U11>0.3612</PDBx:U11>
         <PDBx:U12>-0.0966</PDBx:U12>
         <PDBx:U13>0.0812</PDBx:U13>
         <PDBx:U22>0.2649</PDBx:U22>
         <PDBx:U23>-0.0526</PDBx:U23>
         <PDBx:U33>0.2547</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="623">
         <PDBx:U11>0.3506</PDBx:U11>
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         <PDBx:U23>-0.0650</PDBx:U23>
         <PDBx:U33>0.2471</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="624">
         <PDBx:U11>0.3854</PDBx:U11>
         <PDBx:U12>-0.0571</PDBx:U12>
         <PDBx:U13>0.0637</PDBx:U13>
         <PDBx:U22>0.2366</PDBx:U22>
         <PDBx:U23>-0.0210</PDBx:U23>
         <PDBx:U33>0.2433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="625">
         <PDBx:U11>0.4371</PDBx:U11>
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         <PDBx:U13>0.0586</PDBx:U13>
         <PDBx:U22>0.2785</PDBx:U22>
         <PDBx:U23>-0.0124</PDBx:U23>
         <PDBx:U33>0.2858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="626">
         <PDBx:U11>0.4399</PDBx:U11>
         <PDBx:U12>-0.0440</PDBx:U12>
         <PDBx:U13>0.0614</PDBx:U13>
         <PDBx:U22>0.2686</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.2787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="627">
         <PDBx:U11>0.4382</PDBx:U11>
         <PDBx:U12>-0.0341</PDBx:U12>
         <PDBx:U13>0.0627</PDBx:U13>
         <PDBx:U22>0.2623</PDBx:U22>
         <PDBx:U23>0.0048</PDBx:U23>
         <PDBx:U33>0.2681</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="628">
         <PDBx:U11>0.4222</PDBx:U11>
         <PDBx:U12>-0.0557</PDBx:U12>
         <PDBx:U13>0.0432</PDBx:U13>
         <PDBx:U22>0.2845</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.2765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="629">
         <PDBx:U11>0.4452</PDBx:U11>
         <PDBx:U12>-0.0482</PDBx:U12>
         <PDBx:U13>0.0385</PDBx:U13>
         <PDBx:U22>0.3176</PDBx:U22>
         <PDBx:U23>0.0043</PDBx:U23>
         <PDBx:U33>0.2930</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="630">
         <PDBx:U11>0.4015</PDBx:U11>
         <PDBx:U12>-0.0592</PDBx:U12>
         <PDBx:U13>0.0369</PDBx:U13>
         <PDBx:U22>0.2656</PDBx:U22>
         <PDBx:U23>-0.0104</PDBx:U23>
         <PDBx:U33>0.2553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="631">
         <PDBx:U11>0.4092</PDBx:U11>
         <PDBx:U12>-0.0556</PDBx:U12>
         <PDBx:U13>0.0236</PDBx:U13>
         <PDBx:U22>0.3073</PDBx:U22>
         <PDBx:U23>0.0085</PDBx:U23>
         <PDBx:U33>0.2634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="632">
         <PDBx:U11>0.4167</PDBx:U11>
         <PDBx:U12>-0.0484</PDBx:U12>
         <PDBx:U13>0.0631</PDBx:U13>
         <PDBx:U22>0.2449</PDBx:U22>
         <PDBx:U23>-0.0126</PDBx:U23>
         <PDBx:U33>0.2557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="633">
         <PDBx:U11>0.4253</PDBx:U11>
         <PDBx:U12>-0.0450</PDBx:U12>
         <PDBx:U13>0.0677</PDBx:U13>
         <PDBx:U22>0.2414</PDBx:U22>
         <PDBx:U23>-0.0081</PDBx:U23>
         <PDBx:U33>0.2532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="634">
         <PDBx:U11>0.4621</PDBx:U11>
         <PDBx:U12>-0.0391</PDBx:U12>
         <PDBx:U13>0.0804</PDBx:U13>
         <PDBx:U22>0.2618</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.2854</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="635">
         <PDBx:U11>0.4665</PDBx:U11>
         <PDBx:U12>-0.0307</PDBx:U12>
         <PDBx:U13>0.0824</PDBx:U13>
         <PDBx:U22>0.2597</PDBx:U22>
         <PDBx:U23>0.0090</PDBx:U23>
         <PDBx:U33>0.2792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="636">
         <PDBx:U11>0.4297</PDBx:U11>
         <PDBx:U12>-0.0440</PDBx:U12>
         <PDBx:U13>0.0891</PDBx:U13>
         <PDBx:U22>0.2267</PDBx:U22>
         <PDBx:U23>-0.0118</PDBx:U23>
         <PDBx:U33>0.2604</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="637">
         <PDBx:U11>0.4589</PDBx:U11>
         <PDBx:U12>-0.0416</PDBx:U12>
         <PDBx:U13>0.1030</PDBx:U13>
         <PDBx:U22>0.2356</PDBx:U22>
         <PDBx:U23>-0.0089</PDBx:U23>
         <PDBx:U33>0.2849</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="638">
         <PDBx:U11>0.5052</PDBx:U11>
         <PDBx:U12>-0.0290</PDBx:U12>
         <PDBx:U13>0.1066</PDBx:U13>
         <PDBx:U22>0.2657</PDBx:U22>
         <PDBx:U23>0.0016</PDBx:U23>
         <PDBx:U33>0.3235</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="639">
         <PDBx:U11>0.5343</PDBx:U11>
         <PDBx:U12>-0.0199</PDBx:U12>
         <PDBx:U13>0.1144</PDBx:U13>
         <PDBx:U22>0.2761</PDBx:U22>
         <PDBx:U23>0.0133</PDBx:U23>
         <PDBx:U33>0.3439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="640">
         <PDBx:U11>0.5090</PDBx:U11>
         <PDBx:U12>-0.0527</PDBx:U12>
         <PDBx:U13>0.1103</PDBx:U13>
         <PDBx:U22>0.2914</PDBx:U22>
         <PDBx:U23>-0.0202</PDBx:U23>
         <PDBx:U33>0.3451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="641">
         <PDBx:U11>0.4944</PDBx:U11>
         <PDBx:U12>-0.0538</PDBx:U12>
         <PDBx:U13>0.1252</PDBx:U13>
         <PDBx:U22>0.2521</PDBx:U22>
         <PDBx:U23>-0.0192</PDBx:U23>
         <PDBx:U33>0.3264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="642">
         <PDBx:U11>0.5165</PDBx:U11>
         <PDBx:U12>-0.0537</PDBx:U12>
         <PDBx:U13>0.1328</PDBx:U13>
         <PDBx:U22>0.2568</PDBx:U22>
         <PDBx:U23>-0.0122</PDBx:U23>
         <PDBx:U33>0.3412</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="643">
         <PDBx:U11>0.4560</PDBx:U11>
         <PDBx:U12>-0.0678</PDBx:U12>
         <PDBx:U13>0.1297</PDBx:U13>
         <PDBx:U22>0.2237</PDBx:U22>
         <PDBx:U23>-0.0314</PDBx:U23>
         <PDBx:U33>0.2988</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="644">
         <PDBx:U11>0.5153</PDBx:U11>
         <PDBx:U12>-0.0273</PDBx:U12>
         <PDBx:U13>0.1018</PDBx:U13>
         <PDBx:U22>0.2832</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.3368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="645">
         <PDBx:U11>0.5154</PDBx:U11>
         <PDBx:U12>-0.0276</PDBx:U12>
         <PDBx:U13>0.1017</PDBx:U13>
         <PDBx:U22>0.2836</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.3371</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="646">
         <PDBx:U11>0.5397</PDBx:U11>
         <PDBx:U12>-0.0125</PDBx:U12>
         <PDBx:U13>0.1076</PDBx:U13>
         <PDBx:U22>0.2923</PDBx:U22>
         <PDBx:U23>0.0102</PDBx:U23>
         <PDBx:U33>0.3537</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="647">
         <PDBx:U11>0.5370</PDBx:U11>
         <PDBx:U12>-0.0131</PDBx:U12>
         <PDBx:U13>0.1069</PDBx:U13>
         <PDBx:U22>0.2910</PDBx:U22>
         <PDBx:U23>0.0097</PDBx:U23>
         <PDBx:U33>0.3514</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="648">
         <PDBx:U11>0.5531</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>0.0986</PDBx:U13>
         <PDBx:U22>0.3169</PDBx:U22>
         <PDBx:U23>0.0293</PDBx:U23>
         <PDBx:U33>0.3599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="649">
         <PDBx:U11>0.5532</PDBx:U11>
         <PDBx:U12>0.0010</PDBx:U12>
         <PDBx:U13>0.0988</PDBx:U13>
         <PDBx:U22>0.3166</PDBx:U22>
         <PDBx:U23>0.0289</PDBx:U23>
         <PDBx:U33>0.3600</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="650">
         <PDBx:U11>0.5407</PDBx:U11>
         <PDBx:U12>0.0191</PDBx:U12>
         <PDBx:U13>0.1053</PDBx:U13>
         <PDBx:U22>0.2933</PDBx:U22>
         <PDBx:U23>0.0441</PDBx:U23>
         <PDBx:U33>0.3405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="651">
         <PDBx:U11>0.5335</PDBx:U11>
         <PDBx:U12>0.0182</PDBx:U12>
         <PDBx:U13>0.1062</PDBx:U13>
         <PDBx:U22>0.2839</PDBx:U22>
         <PDBx:U23>0.0434</PDBx:U23>
         <PDBx:U33>0.3332</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="652">
         <PDBx:U11>0.5268</PDBx:U11>
         <PDBx:U12>-0.0152</PDBx:U12>
         <PDBx:U13>0.1067</PDBx:U13>
         <PDBx:U22>0.2855</PDBx:U22>
         <PDBx:U23>0.0040</PDBx:U23>
         <PDBx:U33>0.3438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="653">
         <PDBx:U11>0.5176</PDBx:U11>
         <PDBx:U12>-0.0166</PDBx:U12>
         <PDBx:U13>0.1028</PDBx:U13>
         <PDBx:U22>0.2827</PDBx:U22>
         <PDBx:U23>0.0043</PDBx:U23>
         <PDBx:U33>0.3357</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="654">
         <PDBx:U11>0.5232</PDBx:U11>
         <PDBx:U12>-0.0307</PDBx:U12>
         <PDBx:U13>0.1140</PDBx:U13>
         <PDBx:U22>0.2839</PDBx:U22>
         <PDBx:U23>-0.0127</PDBx:U23>
         <PDBx:U33>0.3488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="655">
         <PDBx:U11>0.5002</PDBx:U11>
         <PDBx:U12>0.0030</PDBx:U12>
         <PDBx:U13>0.1087</PDBx:U13>
         <PDBx:U22>0.2576</PDBx:U22>
         <PDBx:U23>0.0194</PDBx:U23>
         <PDBx:U33>0.3088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="656">
         <PDBx:U11>0.4449</PDBx:U11>
         <PDBx:U12>-0.0216</PDBx:U12>
         <PDBx:U13>0.0877</PDBx:U13>
         <PDBx:U22>0.2376</PDBx:U22>
         <PDBx:U23>0.0059</PDBx:U23>
         <PDBx:U33>0.2683</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="657">
         <PDBx:U11>0.5205</PDBx:U11>
         <PDBx:U12>-0.0309</PDBx:U12>
         <PDBx:U13>0.1108</PDBx:U13>
         <PDBx:U22>0.2857</PDBx:U22>
         <PDBx:U23>-0.0124</PDBx:U23>
         <PDBx:U33>0.3462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="658">
         <PDBx:U11>0.5136</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0836</PDBx:U13>
         <PDBx:U22>0.3037</PDBx:U22>
         <PDBx:U23>0.0290</PDBx:U23>
         <PDBx:U33>0.3228</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="659">
         <PDBx:U11>0.5290</PDBx:U11>
         <PDBx:U12>0.0023</PDBx:U12>
         <PDBx:U13>0.0732</PDBx:U13>
         <PDBx:U22>0.3412</PDBx:U22>
         <PDBx:U23>0.0444</PDBx:U23>
         <PDBx:U33>0.3306</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="660">
         <PDBx:U11>0.5825</PDBx:U11>
         <PDBx:U12>0.0102</PDBx:U12>
         <PDBx:U13>0.0803</PDBx:U13>
         <PDBx:U22>0.3828</PDBx:U22>
         <PDBx:U23>0.0566</PDBx:U23>
         <PDBx:U33>0.3739</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="661">
         <PDBx:U11>0.5919</PDBx:U11>
         <PDBx:U12>0.0253</PDBx:U12>
         <PDBx:U13>0.0795</PDBx:U13>
         <PDBx:U22>0.3990</PDBx:U22>
         <PDBx:U23>0.0744</PDBx:U23>
         <PDBx:U33>0.3766</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="662">
         <PDBx:U11>0.5179</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>0.0588</PDBx:U13>
         <PDBx:U22>0.3545</PDBx:U22>
         <PDBx:U23>0.0372</PDBx:U23>
         <PDBx:U33>0.3216</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="663">
         <PDBx:U11>0.5323</PDBx:U11>
         <PDBx:U12>-0.0074</PDBx:U12>
         <PDBx:U13>0.0503</PDBx:U13>
         <PDBx:U22>0.3910</PDBx:U22>
         <PDBx:U23>0.0479</PDBx:U23>
         <PDBx:U33>0.3243</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="664">
         <PDBx:U11>0.5421</PDBx:U11>
         <PDBx:U12>-0.0132</PDBx:U12>
         <PDBx:U13>0.0504</PDBx:U13>
         <PDBx:U22>0.4009</PDBx:U22>
         <PDBx:U23>0.0447</PDBx:U23>
         <PDBx:U33>0.3244</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="665">
         <PDBx:U11>0.5196</PDBx:U11>
         <PDBx:U12>0.0012</PDBx:U12>
         <PDBx:U13>0.0408</PDBx:U13>
         <PDBx:U22>0.4084</PDBx:U22>
         <PDBx:U23>0.0631</PDBx:U23>
         <PDBx:U33>0.3067</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="666">
         <PDBx:U11>0.6098</PDBx:U11>
         <PDBx:U12>-0.0097</PDBx:U12>
         <PDBx:U13>0.0415</PDBx:U13>
         <PDBx:U22>0.4970</PDBx:U22>
         <PDBx:U23>0.0557</PDBx:U23>
         <PDBx:U33>0.3799</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="667">
         <PDBx:U11>0.5528</PDBx:U11>
         <PDBx:U12>-0.0019</PDBx:U12>
         <PDBx:U13>0.0344</PDBx:U13>
         <PDBx:U22>0.4610</PDBx:U22>
         <PDBx:U23>0.0676</PDBx:U23>
         <PDBx:U33>0.3269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="668">
         <PDBx:U11>0.5422</PDBx:U11>
         <PDBx:U12>0.0113</PDBx:U12>
         <PDBx:U13>0.0373</PDBx:U13>
         <PDBx:U22>0.4467</PDBx:U22>
         <PDBx:U23>0.0728</PDBx:U23>
         <PDBx:U33>0.3336</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="669">
         <PDBx:U11>0.5951</PDBx:U11>
         <PDBx:U12>0.0006</PDBx:U12>
         <PDBx:U13>0.0223</PDBx:U13>
         <PDBx:U22>0.5401</PDBx:U22>
         <PDBx:U23>0.0813</PDBx:U23>
         <PDBx:U33>0.3610</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="670">
         <PDBx:U11>0.6087</PDBx:U11>
         <PDBx:U12>0.0161</PDBx:U12>
         <PDBx:U13>0.0253</PDBx:U13>
         <PDBx:U22>0.5471</PDBx:U22>
         <PDBx:U23>0.0865</PDBx:U23>
         <PDBx:U33>0.3939</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="671">
         <PDBx:U11>0.5825</PDBx:U11>
         <PDBx:U12>0.0078</PDBx:U12>
         <PDBx:U13>0.0166</PDBx:U13>
         <PDBx:U22>0.5371</PDBx:U22>
         <PDBx:U23>0.0897</PDBx:U23>
         <PDBx:U33>0.3528</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="672">
         <PDBx:U11>0.5493</PDBx:U11>
         <PDBx:U12>0.0003</PDBx:U12>
         <PDBx:U13>0.0869</PDBx:U13>
         <PDBx:U22>0.3356</PDBx:U22>
         <PDBx:U23>0.0487</PDBx:U23>
         <PDBx:U33>0.3400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="673">
         <PDBx:U11>0.5890</PDBx:U11>
         <PDBx:U12>0.0045</PDBx:U12>
         <PDBx:U13>0.0938</PDBx:U13>
         <PDBx:U22>0.3665</PDBx:U22>
         <PDBx:U23>0.0614</PDBx:U23>
         <PDBx:U33>0.3692</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="674">
         <PDBx:U11>0.6020</PDBx:U11>
         <PDBx:U12>0.0142</PDBx:U12>
         <PDBx:U13>0.1090</PDBx:U13>
         <PDBx:U22>0.3475</PDBx:U22>
         <PDBx:U23>0.0693</PDBx:U23>
         <PDBx:U33>0.3812</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="675">
         <PDBx:U11>0.6150</PDBx:U11>
         <PDBx:U12>0.0195</PDBx:U12>
         <PDBx:U13>0.1151</PDBx:U13>
         <PDBx:U22>0.3506</PDBx:U22>
         <PDBx:U23>0.0843</PDBx:U23>
         <PDBx:U33>0.3856</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="676">
         <PDBx:U11>0.5571</PDBx:U11>
         <PDBx:U12>-0.0094</PDBx:U12>
         <PDBx:U13>0.0968</PDBx:U13>
         <PDBx:U22>0.3344</PDBx:U22>
         <PDBx:U23>0.0514</PDBx:U23>
         <PDBx:U33>0.3358</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="677">
         <PDBx:U11>0.6256</PDBx:U11>
         <PDBx:U12>-0.0212</PDBx:U12>
         <PDBx:U13>0.1047</PDBx:U13>
         <PDBx:U22>0.3886</PDBx:U22>
         <PDBx:U23>0.0329</PDBx:U23>
         <PDBx:U33>0.4166</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="678">
         <PDBx:U11>0.6275</PDBx:U11>
         <PDBx:U12>-0.0324</PDBx:U12>
         <PDBx:U13>0.1076</PDBx:U13>
         <PDBx:U22>0.3962</PDBx:U22>
         <PDBx:U23>0.0256</PDBx:U23>
         <PDBx:U33>0.4175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="679">
         <PDBx:U11>0.6045</PDBx:U11>
         <PDBx:U12>-0.0437</PDBx:U12>
         <PDBx:U13>0.1148</PDBx:U13>
         <PDBx:U22>0.3678</PDBx:U22>
         <PDBx:U23>0.0106</PDBx:U23>
         <PDBx:U33>0.4071</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="680">
         <PDBx:U11>0.5130</PDBx:U11>
         <PDBx:U12>-0.0509</PDBx:U12>
         <PDBx:U13>0.1095</PDBx:U13>
         <PDBx:U22>0.2895</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.3269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="681">
         <PDBx:U11>0.4421</PDBx:U11>
         <PDBx:U12>-0.0490</PDBx:U12>
         <PDBx:U13>0.0980</PDBx:U13>
         <PDBx:U22>0.2302</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.2556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="682">
         <PDBx:U11>0.5244</PDBx:U11>
         <PDBx:U12>-0.0606</PDBx:U12>
         <PDBx:U13>0.1156</PDBx:U13>
         <PDBx:U22>0.3045</PDBx:U22>
         <PDBx:U23>-0.0146</PDBx:U23>
         <PDBx:U33>0.3498</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="683">
         <PDBx:U11>0.5571</PDBx:U11>
         <PDBx:U12>0.0158</PDBx:U12>
         <PDBx:U13>0.1159</PDBx:U13>
         <PDBx:U22>0.2863</PDBx:U22>
         <PDBx:U23>0.0595</PDBx:U23>
         <PDBx:U33>0.3440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="684">
         <PDBx:U11>0.5768</PDBx:U11>
         <PDBx:U12>0.0244</PDBx:U12>
         <PDBx:U13>0.1324</PDBx:U13>
         <PDBx:U22>0.2721</PDBx:U22>
         <PDBx:U23>0.0636</PDBx:U23>
         <PDBx:U33>0.3625</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="685">
         <PDBx:U11>0.6146</PDBx:U11>
         <PDBx:U12>0.0489</PDBx:U12>
         <PDBx:U13>0.1336</PDBx:U13>
         <PDBx:U22>0.3078</PDBx:U22>
         <PDBx:U23>0.0810</PDBx:U23>
         <PDBx:U33>0.3975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="686">
         <PDBx:U11>0.7042</PDBx:U11>
         <PDBx:U12>0.0611</PDBx:U12>
         <PDBx:U13>0.1477</PDBx:U13>
         <PDBx:U22>0.3679</PDBx:U22>
         <PDBx:U23>0.0872</PDBx:U23>
         <PDBx:U33>0.4864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="687">
         <PDBx:U11>0.5585</PDBx:U11>
         <PDBx:U12>0.0111</PDBx:U12>
         <PDBx:U13>0.1412</PDBx:U13>
         <PDBx:U22>0.2406</PDBx:U22>
         <PDBx:U23>0.0419</PDBx:U23>
         <PDBx:U33>0.3526</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>0.4753</PDBx:U22>
         <PDBx:U23>0.1641</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.1365</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="704">
         <PDBx:U11>0.8246</PDBx:U11>
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         <PDBx:U13>0.1833</PDBx:U13>
         <PDBx:U22>0.4018</PDBx:U22>
         <PDBx:U23>0.1186</PDBx:U23>
         <PDBx:U33>0.6012</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="705">
         <PDBx:U11>0.7922</PDBx:U11>
         <PDBx:U12>0.0713</PDBx:U12>
         <PDBx:U13>0.1876</PDBx:U13>
         <PDBx:U22>0.3597</PDBx:U22>
         <PDBx:U23>0.0951</PDBx:U23>
         <PDBx:U33>0.5724</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="706">
         <PDBx:U11>0.7779</PDBx:U11>
         <PDBx:U12>0.0631</PDBx:U12>
         <PDBx:U13>0.1711</PDBx:U13>
         <PDBx:U22>0.3782</PDBx:U22>
         <PDBx:U23>0.1233</PDBx:U23>
         <PDBx:U33>0.5440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="707">
         <PDBx:U11>0.8014</PDBx:U11>
         <PDBx:U12>0.0587</PDBx:U12>
         <PDBx:U13>0.1607</PDBx:U13>
         <PDBx:U22>0.4268</PDBx:U22>
         <PDBx:U23>0.1388</PDBx:U23>
         <PDBx:U33>0.5579</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="708">
         <PDBx:U11>0.8351</PDBx:U11>
         <PDBx:U12>0.0597</PDBx:U12>
         <PDBx:U13>0.1670</PDBx:U13>
         <PDBx:U22>0.4437</PDBx:U22>
         <PDBx:U23>0.1593</PDBx:U23>
         <PDBx:U33>0.5821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="709">
         <PDBx:U11>0.7752</PDBx:U11>
         <PDBx:U12>0.0520</PDBx:U12>
         <PDBx:U13>0.1449</PDBx:U13>
         <PDBx:U22>0.4417</PDBx:U22>
         <PDBx:U23>0.1367</PDBx:U23>
         <PDBx:U33>0.5285</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="710">
         <PDBx:U11>0.8142</PDBx:U11>
         <PDBx:U12>0.0535</PDBx:U12>
         <PDBx:U13>0.1557</PDBx:U13>
         <PDBx:U22>0.4556</PDBx:U22>
         <PDBx:U23>0.1690</PDBx:U23>
         <PDBx:U33>0.5512</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="711">
         <PDBx:U11>0.8097</PDBx:U11>
         <PDBx:U12>0.0487</PDBx:U12>
         <PDBx:U13>0.1425</PDBx:U13>
         <PDBx:U22>0.4859</PDBx:U22>
         <PDBx:U23>0.1543</PDBx:U23>
         <PDBx:U33>0.5504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="712">
         <PDBx:U11>0.8652</PDBx:U11>
         <PDBx:U12>0.1206</PDBx:U12>
         <PDBx:U13>0.1885</PDBx:U13>
         <PDBx:U22>0.4359</PDBx:U22>
         <PDBx:U23>0.1300</PDBx:U23>
         <PDBx:U33>0.6455</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="713">
         <PDBx:U11>0.8473</PDBx:U11>
         <PDBx:U12>0.1249</PDBx:U12>
         <PDBx:U13>0.2005</PDBx:U13>
         <PDBx:U22>0.3953</PDBx:U22>
         <PDBx:U23>0.1133</PDBx:U23>
         <PDBx:U33>0.6346</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="714">
         <PDBx:U11>0.8097</PDBx:U11>
         <PDBx:U12>0.1041</PDBx:U12>
         <PDBx:U13>0.2149</PDBx:U13>
         <PDBx:U22>0.3135</PDBx:U22>
         <PDBx:U23>0.0961</PDBx:U23>
         <PDBx:U33>0.5967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="715">
         <PDBx:U11>0.8515</PDBx:U11>
         <PDBx:U12>0.1035</PDBx:U12>
         <PDBx:U13>0.2228</PDBx:U13>
         <PDBx:U22>0.3252</PDBx:U22>
         <PDBx:U23>0.1081</PDBx:U23>
         <PDBx:U33>0.6339</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="716">
         <PDBx:U11>0.9228</PDBx:U11>
         <PDBx:U12>0.1610</PDBx:U12>
         <PDBx:U13>0.2060</PDBx:U13>
         <PDBx:U22>0.4661</PDBx:U22>
         <PDBx:U23>0.1354</PDBx:U23>
         <PDBx:U33>0.7141</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="717">
         <PDBx:U11>0.9055</PDBx:U11>
         <PDBx:U12>0.1746</PDBx:U12>
         <PDBx:U13>0.1898</PDBx:U13>
         <PDBx:U22>0.4937</PDBx:U22>
         <PDBx:U23>0.1602</PDBx:U23>
         <PDBx:U33>0.6942</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="718">
         <PDBx:U11>0.8948</PDBx:U11>
         <PDBx:U12>0.1492</PDBx:U12>
         <PDBx:U13>0.1827</PDBx:U13>
         <PDBx:U22>0.4852</PDBx:U22>
         <PDBx:U23>0.1598</PDBx:U23>
         <PDBx:U33>0.6739</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="719">
         <PDBx:U11>0.7806</PDBx:U11>
         <PDBx:U12>0.0861</PDBx:U12>
         <PDBx:U13>0.2171</PDBx:U13>
         <PDBx:U22>0.2839</PDBx:U22>
         <PDBx:U23>0.0692</PDBx:U23>
         <PDBx:U33>0.5727</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="720">
         <PDBx:U11>0.8256</PDBx:U11>
         <PDBx:U12>0.0646</PDBx:U12>
         <PDBx:U13>0.2288</PDBx:U13>
         <PDBx:U22>0.2951</PDBx:U22>
         <PDBx:U23>0.0507</PDBx:U23>
         <PDBx:U33>0.6189</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.7919</PDBx:U11>
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         <PDBx:U13>0.2247</PDBx:U13>
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         <PDBx:U23>0.0425</PDBx:U23>
         <PDBx:U33>0.5835</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="722">
         <PDBx:U11>0.8395</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>0.2333</PDBx:U13>
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         <PDBx:U23>0.0282</PDBx:U23>
         <PDBx:U33>0.6324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="723">
         <PDBx:U11>0.7066</PDBx:U11>
         <PDBx:U12>0.0327</PDBx:U12>
         <PDBx:U13>0.2117</PDBx:U13>
         <PDBx:U22>0.2198</PDBx:U22>
         <PDBx:U23>0.0511</PDBx:U23>
         <PDBx:U33>0.4958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="724">
         <PDBx:U11>0.6870</PDBx:U11>
         <PDBx:U12>0.0086</PDBx:U12>
         <PDBx:U13>0.2076</PDBx:U13>
         <PDBx:U22>0.2133</PDBx:U22>
         <PDBx:U23>0.0445</PDBx:U23>
         <PDBx:U33>0.4762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="725">
         <PDBx:U11>0.6673</PDBx:U11>
         <PDBx:U12>-0.0008</PDBx:U12>
         <PDBx:U13>0.1918</PDBx:U13>
         <PDBx:U22>0.2403</PDBx:U22>
         <PDBx:U23>0.0349</PDBx:U23>
         <PDBx:U33>0.4606</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="726">
         <PDBx:U11>0.6994</PDBx:U11>
         <PDBx:U12>0.0127</PDBx:U12>
         <PDBx:U13>0.1821</PDBx:U13>
         <PDBx:U22>0.2939</PDBx:U22>
         <PDBx:U23>0.0400</PDBx:U23>
         <PDBx:U33>0.4923</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="727">
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         <PDBx:U12>0.0137</PDBx:U12>
         <PDBx:U13>0.2097</PDBx:U13>
         <PDBx:U22>0.3417</PDBx:U22>
         <PDBx:U23>0.0674</PDBx:U23>
         <PDBx:U33>0.6104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="728">
         <PDBx:U11>0.8764</PDBx:U11>
         <PDBx:U12>0.0219</PDBx:U12>
         <PDBx:U13>0.2254</PDBx:U13>
         <PDBx:U22>0.3384</PDBx:U22>
         <PDBx:U23>0.0798</PDBx:U23>
         <PDBx:U33>0.6536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="729">
         <PDBx:U11>0.9839</PDBx:U11>
         <PDBx:U12>0.0234</PDBx:U12>
         <PDBx:U13>0.2268</PDBx:U13>
         <PDBx:U22>0.4350</PDBx:U22>
         <PDBx:U23>0.1047</PDBx:U23>
         <PDBx:U33>0.7526</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="730">
         <PDBx:U11>1.1222</PDBx:U11>
         <PDBx:U12>0.0337</PDBx:U12>
         <PDBx:U13>0.2422</PDBx:U13>
         <PDBx:U22>0.5193</PDBx:U22>
         <PDBx:U23>0.1200</PDBx:U23>
         <PDBx:U33>0.8871</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="731">
         <PDBx:U11>1.1655</PDBx:U11>
         <PDBx:U12>0.0163</PDBx:U12>
         <PDBx:U13>0.2549</PDBx:U13>
         <PDBx:U22>0.5279</PDBx:U22>
         <PDBx:U23>0.0967</PDBx:U23>
         <PDBx:U33>0.9354</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="732">
         <PDBx:U11>0.6438</PDBx:U11>
         <PDBx:U12>-0.0232</PDBx:U12>
         <PDBx:U13>0.1893</PDBx:U13>
         <PDBx:U22>0.2317</PDBx:U22>
         <PDBx:U23>0.0218</PDBx:U23>
         <PDBx:U33>0.4417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="733">
         <PDBx:U11>0.6323</PDBx:U11>
         <PDBx:U12>-0.0316</PDBx:U12>
         <PDBx:U13>0.1750</PDBx:U13>
         <PDBx:U22>0.2615</PDBx:U22>
         <PDBx:U23>0.0132</PDBx:U23>
         <PDBx:U33>0.4356</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="734">
         <PDBx:U11>0.6123</PDBx:U11>
         <PDBx:U12>-0.0367</PDBx:U12>
         <PDBx:U13>0.1714</PDBx:U13>
         <PDBx:U22>0.2507</PDBx:U22>
         <PDBx:U23>0.0213</PDBx:U23>
         <PDBx:U33>0.4123</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="735">
         <PDBx:U11>0.6598</PDBx:U11>
         <PDBx:U12>-0.0512</PDBx:U12>
         <PDBx:U13>0.1787</PDBx:U13>
         <PDBx:U22>0.2899</PDBx:U22>
         <PDBx:U23>0.0181</PDBx:U23>
         <PDBx:U33>0.4612</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="736">
         <PDBx:U11>0.6467</PDBx:U11>
         <PDBx:U12>-0.0510</PDBx:U12>
         <PDBx:U13>0.1738</PDBx:U13>
         <PDBx:U22>0.2942</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.4609</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="737">
         <PDBx:U11>0.6370</PDBx:U11>
         <PDBx:U12>-0.0495</PDBx:U12>
         <PDBx:U13>0.1737</PDBx:U13>
         <PDBx:U22>0.2880</PDBx:U22>
         <PDBx:U23>-0.0179</PDBx:U23>
         <PDBx:U33>0.4559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="738">
         <PDBx:U11>0.6328</PDBx:U11>
         <PDBx:U12>-0.0705</PDBx:U12>
         <PDBx:U13>0.1714</PDBx:U13>
         <PDBx:U22>0.3065</PDBx:U22>
         <PDBx:U23>-0.0362</PDBx:U23>
         <PDBx:U33>0.4626</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="739">
         <PDBx:U11>0.5417</PDBx:U11>
         <PDBx:U12>-0.0357</PDBx:U12>
         <PDBx:U13>0.1621</PDBx:U13>
         <PDBx:U22>0.2127</PDBx:U22>
         <PDBx:U23>-0.0117</PDBx:U23>
         <PDBx:U33>0.3596</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="740">
         <PDBx:U11>0.6134</PDBx:U11>
         <PDBx:U12>-0.0260</PDBx:U12>
         <PDBx:U13>0.1604</PDBx:U13>
         <PDBx:U22>0.2700</PDBx:U22>
         <PDBx:U23>0.0319</PDBx:U23>
         <PDBx:U33>0.4086</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="741">
         <PDBx:U11>0.6495</PDBx:U11>
         <PDBx:U12>-0.0303</PDBx:U12>
         <PDBx:U13>0.1571</PDBx:U13>
         <PDBx:U22>0.3171</PDBx:U22>
         <PDBx:U23>0.0406</PDBx:U23>
         <PDBx:U33>0.4397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="742">
         <PDBx:U11>0.5805</PDBx:U11>
         <PDBx:U12>-0.0436</PDBx:U12>
         <PDBx:U13>0.1493</PDBx:U13>
         <PDBx:U22>0.2768</PDBx:U22>
         <PDBx:U23>0.0244</PDBx:U23>
         <PDBx:U33>0.3793</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="743">
         <PDBx:U11>0.5685</PDBx:U11>
         <PDBx:U12>-0.0396</PDBx:U12>
         <PDBx:U13>0.1374</PDBx:U13>
         <PDBx:U22>0.2864</PDBx:U22>
         <PDBx:U23>0.0233</PDBx:U23>
         <PDBx:U33>0.3670</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="744">
         <PDBx:U11>0.6637</PDBx:U11>
         <PDBx:U12>-0.0139</PDBx:U12>
         <PDBx:U13>0.1488</PDBx:U13>
         <PDBx:U22>0.3408</PDBx:U22>
         <PDBx:U23>0.0608</PDBx:U23>
         <PDBx:U33>0.4432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="745">
         <PDBx:U11>0.7370</PDBx:U11>
         <PDBx:U12>-0.0160</PDBx:U12>
         <PDBx:U13>0.1486</PDBx:U13>
         <PDBx:U22>0.4226</PDBx:U22>
         <PDBx:U23>0.0766</PDBx:U23>
         <PDBx:U33>0.5054</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="746">
         <PDBx:U11>0.7820</PDBx:U11>
         <PDBx:U12>0.0015</PDBx:U12>
         <PDBx:U13>0.1429</PDBx:U13>
         <PDBx:U22>0.4740</PDBx:U22>
         <PDBx:U23>0.1010</PDBx:U23>
         <PDBx:U33>0.5380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="747">
         <PDBx:U11>0.7313</PDBx:U11>
         <PDBx:U12>-0.0269</PDBx:U12>
         <PDBx:U13>0.1408</PDBx:U13>
         <PDBx:U22>0.4462</PDBx:U22>
         <PDBx:U23>0.0651</PDBx:U23>
         <PDBx:U33>0.5012</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="748">
         <PDBx:U11>0.5724</PDBx:U11>
         <PDBx:U12>-0.0595</PDBx:U12>
         <PDBx:U13>0.1562</PDBx:U13>
         <PDBx:U22>0.2687</PDBx:U22>
         <PDBx:U23>0.0125</PDBx:U23>
         <PDBx:U33>0.3792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="749">
         <PDBx:U11>0.5798</PDBx:U11>
         <PDBx:U12>-0.0707</PDBx:U12>
         <PDBx:U13>0.1507</PDBx:U13>
         <PDBx:U22>0.3033</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.3966</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="750">
         <PDBx:U11>0.6188</PDBx:U11>
         <PDBx:U12>-0.0701</PDBx:U12>
         <PDBx:U13>0.1490</PDBx:U13>
         <PDBx:U22>0.3527</PDBx:U22>
         <PDBx:U23>0.0075</PDBx:U23>
         <PDBx:U33>0.4290</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="751">
         <PDBx:U11>0.5599</PDBx:U11>
         <PDBx:U12>-0.0702</PDBx:U12>
         <PDBx:U13>0.1410</PDBx:U13>
         <PDBx:U22>0.3141</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.3736</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="752">
         <PDBx:U11>0.5462</PDBx:U11>
         <PDBx:U12>-0.0881</PDBx:U12>
         <PDBx:U13>0.1590</PDBx:U13>
         <PDBx:U22>0.2707</PDBx:U22>
         <PDBx:U23>-0.0123</PDBx:U23>
         <PDBx:U33>0.3732</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="753">
         <PDBx:U11>0.5833</PDBx:U11>
         <PDBx:U12>-0.0922</PDBx:U12>
         <PDBx:U13>0.1582</PDBx:U13>
         <PDBx:U22>0.3110</PDBx:U22>
         <PDBx:U23>-0.0246</PDBx:U23>
         <PDBx:U33>0.4181</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="754">
         <PDBx:U11>0.5383</PDBx:U11>
         <PDBx:U12>-0.0967</PDBx:U12>
         <PDBx:U13>0.1488</PDBx:U13>
         <PDBx:U22>0.2967</PDBx:U22>
         <PDBx:U23>-0.0363</PDBx:U23>
         <PDBx:U33>0.3851</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="755">
         <PDBx:U11>0.5731</PDBx:U11>
         <PDBx:U12>-0.0917</PDBx:U12>
         <PDBx:U13>0.1675</PDBx:U13>
         <PDBx:U22>0.2728</PDBx:U22>
         <PDBx:U23>-0.0232</PDBx:U23>
         <PDBx:U33>0.4028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="756">
         <PDBx:U11>0.5478</PDBx:U11>
         <PDBx:U12>-0.1017</PDBx:U12>
         <PDBx:U13>0.1479</PDBx:U13>
         <PDBx:U22>0.3136</PDBx:U22>
         <PDBx:U23>-0.0454</PDBx:U23>
         <PDBx:U33>0.4009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="757">
         <PDBx:U11>0.6213</PDBx:U11>
         <PDBx:U12>-0.0971</PDBx:U12>
         <PDBx:U13>0.1679</PDBx:U13>
         <PDBx:U22>0.3253</PDBx:U22>
         <PDBx:U23>-0.0350</PDBx:U23>
         <PDBx:U33>0.4571</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="758">
         <PDBx:U11>0.5695</PDBx:U11>
         <PDBx:U12>-0.1027</PDBx:U12>
         <PDBx:U13>0.1577</PDBx:U13>
         <PDBx:U22>0.3087</PDBx:U22>
         <PDBx:U23>-0.0458</PDBx:U23>
         <PDBx:U33>0.4165</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="759">
         <PDBx:U11>0.5945</PDBx:U11>
         <PDBx:U12>-0.0700</PDBx:U12>
         <PDBx:U13>0.1577</PDBx:U13>
         <PDBx:U22>0.3140</PDBx:U22>
         <PDBx:U23>0.0231</PDBx:U23>
         <PDBx:U33>0.3942</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="760">
         <PDBx:U11>0.5691</PDBx:U11>
         <PDBx:U12>-0.0690</PDBx:U12>
         <PDBx:U13>0.1578</PDBx:U13>
         <PDBx:U22>0.3021</PDBx:U22>
         <PDBx:U23>0.0344</PDBx:U23>
         <PDBx:U33>0.3581</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="761">
         <PDBx:U11>0.6166</PDBx:U11>
         <PDBx:U12>-0.0613</PDBx:U12>
         <PDBx:U13>0.1631</PDBx:U13>
         <PDBx:U22>0.3329</PDBx:U22>
         <PDBx:U23>0.0580</PDBx:U23>
         <PDBx:U33>0.3903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="762">
         <PDBx:U11>0.6792</PDBx:U11>
         <PDBx:U12>-0.0603</PDBx:U12>
         <PDBx:U13>0.1702</PDBx:U13>
         <PDBx:U22>0.3682</PDBx:U22>
         <PDBx:U23>0.0639</PDBx:U23>
         <PDBx:U33>0.4537</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="763">
         <PDBx:U11>0.5657</PDBx:U11>
         <PDBx:U12>-0.0844</PDBx:U12>
         <PDBx:U13>0.1661</PDBx:U13>
         <PDBx:U22>0.3128</PDBx:U22>
         <PDBx:U23>0.0278</PDBx:U23>
         <PDBx:U33>0.3621</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="764">
         <PDBx:U11>0.6326</PDBx:U11>
         <PDBx:U12>-0.0558</PDBx:U12>
         <PDBx:U13>0.1598</PDBx:U13>
         <PDBx:U22>0.3666</PDBx:U22>
         <PDBx:U23>0.0721</PDBx:U23>
         <PDBx:U33>0.3915</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="765">
         <PDBx:U11>0.6728</PDBx:U11>
         <PDBx:U12>-0.0486</PDBx:U12>
         <PDBx:U13>0.1634</PDBx:U13>
         <PDBx:U22>0.3972</PDBx:U22>
         <PDBx:U23>0.0984</PDBx:U23>
         <PDBx:U33>0.4161</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="766">
         <PDBx:U11>0.7421</PDBx:U11>
         <PDBx:U12>-0.0595</PDBx:U12>
         <PDBx:U13>0.1784</PDBx:U13>
         <PDBx:U22>0.4411</PDBx:U22>
         <PDBx:U23>0.1074</PDBx:U23>
         <PDBx:U33>0.4869</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="767">
         <PDBx:U11>0.8072</PDBx:U11>
         <PDBx:U12>-0.0528</PDBx:U12>
         <PDBx:U13>0.1830</PDBx:U13>
         <PDBx:U22>0.4803</PDBx:U22>
         <PDBx:U23>0.1260</PDBx:U23>
         <PDBx:U33>0.5454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="768">
         <PDBx:U11>0.6870</PDBx:U11>
         <PDBx:U12>-0.0484</PDBx:U12>
         <PDBx:U13>0.1595</PDBx:U13>
         <PDBx:U22>0.4457</PDBx:U22>
         <PDBx:U23>0.1068</PDBx:U23>
         <PDBx:U33>0.4140</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="769">
         <PDBx:U11>0.6435</PDBx:U11>
         <PDBx:U12>-0.0474</PDBx:U12>
         <PDBx:U13>0.1493</PDBx:U13>
         <PDBx:U22>0.4227</PDBx:U22>
         <PDBx:U23>0.0856</PDBx:U23>
         <PDBx:U33>0.3761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="770">
         <PDBx:U11>0.6047</PDBx:U11>
         <PDBx:U12>-0.0558</PDBx:U12>
         <PDBx:U13>0.1526</PDBx:U13>
         <PDBx:U22>0.3694</PDBx:U22>
         <PDBx:U23>0.0646</PDBx:U23>
         <PDBx:U33>0.3587</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="771">
         <PDBx:U11>0.6930</PDBx:U11>
         <PDBx:U12>-0.0762</PDBx:U12>
         <PDBx:U13>0.1860</PDBx:U13>
         <PDBx:U22>0.3995</PDBx:U22>
         <PDBx:U23>0.0952</PDBx:U23>
         <PDBx:U33>0.4472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="772">
         <PDBx:U11>0.7293</PDBx:U11>
         <PDBx:U12>-0.0910</PDBx:U12>
         <PDBx:U13>0.2001</PDBx:U13>
         <PDBx:U22>0.4151</PDBx:U22>
         <PDBx:U23>0.1022</PDBx:U23>
         <PDBx:U33>0.4868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="773">
         <PDBx:U11>0.7224</PDBx:U11>
         <PDBx:U12>-0.1007</PDBx:U12>
         <PDBx:U13>0.2037</PDBx:U13>
         <PDBx:U22>0.3877</PDBx:U22>
         <PDBx:U23>0.0821</PDBx:U23>
         <PDBx:U33>0.4968</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="774">
         <PDBx:U11>0.7238</PDBx:U11>
         <PDBx:U12>-0.1186</PDBx:U12>
         <PDBx:U13>0.2142</PDBx:U13>
         <PDBx:U22>0.3808</PDBx:U22>
         <PDBx:U23>0.0798</PDBx:U23>
         <PDBx:U33>0.5053</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="775">
         <PDBx:U11>0.7156</PDBx:U11>
         <PDBx:U12>-0.1055</PDBx:U12>
         <PDBx:U13>0.2079</PDBx:U13>
         <PDBx:U22>0.4294</PDBx:U22>
         <PDBx:U23>0.1051</PDBx:U23>
         <PDBx:U33>0.4721</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="776">
         <PDBx:U11>0.7036</PDBx:U11>
         <PDBx:U12>-0.1128</PDBx:U12>
         <PDBx:U13>0.2053</PDBx:U13>
         <PDBx:U22>0.4455</PDBx:U22>
         <PDBx:U23>0.0800</PDBx:U23>
         <PDBx:U33>0.4758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="777">
         <PDBx:U11>0.6200</PDBx:U11>
         <PDBx:U12>-0.1048</PDBx:U12>
         <PDBx:U13>0.1946</PDBx:U13>
         <PDBx:U22>0.3663</PDBx:U22>
         <PDBx:U23>0.0634</PDBx:U23>
         <PDBx:U33>0.3991</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="778">
         <PDBx:U11>0.6393</PDBx:U11>
         <PDBx:U12>-0.1280</PDBx:U12>
         <PDBx:U13>0.2154</PDBx:U13>
         <PDBx:U22>0.4024</PDBx:U22>
         <PDBx:U23>0.0788</PDBx:U23>
         <PDBx:U33>0.4182</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="779">
         <PDBx:U11>0.6994</PDBx:U11>
         <PDBx:U12>-0.0904</PDBx:U12>
         <PDBx:U13>0.1951</PDBx:U13>
         <PDBx:U22>0.3608</PDBx:U22>
         <PDBx:U23>0.0681</PDBx:U23>
         <PDBx:U33>0.4795</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="780">
         <PDBx:U11>0.7278</PDBx:U11>
         <PDBx:U12>-0.0988</PDBx:U12>
         <PDBx:U13>0.1978</PDBx:U13>
         <PDBx:U22>0.3757</PDBx:U22>
         <PDBx:U23>0.0489</PDBx:U23>
         <PDBx:U33>0.5207</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="781">
         <PDBx:U11>0.7252</PDBx:U11>
         <PDBx:U12>-0.0826</PDBx:U12>
         <PDBx:U13>0.1929</PDBx:U13>
         <PDBx:U22>0.3570</PDBx:U22>
         <PDBx:U23>0.0461</PDBx:U23>
         <PDBx:U33>0.5164</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="782">
         <PDBx:U11>0.6415</PDBx:U11>
         <PDBx:U12>-0.0767</PDBx:U12>
         <PDBx:U13>0.1826</PDBx:U13>
         <PDBx:U22>0.2933</PDBx:U22>
         <PDBx:U23>0.0330</PDBx:U23>
         <PDBx:U33>0.4386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="783">
         <PDBx:U11>0.7251</PDBx:U11>
         <PDBx:U12>-0.1104</PDBx:U12>
         <PDBx:U13>0.1925</PDBx:U13>
         <PDBx:U22>0.4055</PDBx:U22>
         <PDBx:U23>0.0271</PDBx:U23>
         <PDBx:U33>0.5328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="784">
         <PDBx:U11>0.7351</PDBx:U11>
         <PDBx:U12>-0.1243</PDBx:U12>
         <PDBx:U13>0.1954</PDBx:U13>
         <PDBx:U22>0.4124</PDBx:U22>
         <PDBx:U23>0.0083</PDBx:U23>
         <PDBx:U33>0.5555</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="785">
         <PDBx:U11>0.8301</PDBx:U11>
         <PDBx:U12>-0.1411</PDBx:U12>
         <PDBx:U13>0.2096</PDBx:U13>
         <PDBx:U22>0.4806</PDBx:U22>
         <PDBx:U23>0.0134</PDBx:U23>
         <PDBx:U33>0.6496</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="786">
         <PDBx:U11>0.6909</PDBx:U11>
         <PDBx:U12>-0.1342</PDBx:U12>
         <PDBx:U13>0.1889</PDBx:U13>
         <PDBx:U22>0.4067</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.5266</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="787">
         <PDBx:U11>0.7359</PDBx:U11>
         <PDBx:U12>-0.0752</PDBx:U12>
         <PDBx:U13>0.2012</PDBx:U13>
         <PDBx:U22>0.3318</PDBx:U22>
         <PDBx:U23>0.0600</PDBx:U23>
         <PDBx:U33>0.5198</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="788">
         <PDBx:U11>0.7706</PDBx:U11>
         <PDBx:U12>-0.0583</PDBx:U12>
         <PDBx:U13>0.1999</PDBx:U13>
         <PDBx:U22>0.3495</PDBx:U22>
         <PDBx:U23>0.0596</PDBx:U23>
         <PDBx:U33>0.5532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="789">
         <PDBx:U11>0.7795</PDBx:U11>
         <PDBx:U12>-0.0683</PDBx:U12>
         <PDBx:U13>0.2114</PDBx:U13>
         <PDBx:U22>0.3280</PDBx:U22>
         <PDBx:U23>0.0466</PDBx:U23>
         <PDBx:U33>0.5674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="790">
         <PDBx:U11>0.8134</PDBx:U11>
         <PDBx:U12>-0.0762</PDBx:U12>
         <PDBx:U13>0.2236</PDBx:U13>
         <PDBx:U22>0.3282</PDBx:U22>
         <PDBx:U23>0.0549</PDBx:U23>
         <PDBx:U33>0.5979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="791">
         <PDBx:U11>0.8867</PDBx:U11>
         <PDBx:U12>-0.0382</PDBx:U12>
         <PDBx:U13>0.2008</PDBx:U13>
         <PDBx:U22>0.4482</PDBx:U22>
         <PDBx:U23>0.0872</PDBx:U23>
         <PDBx:U33>0.6568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="792">
         <PDBx:U11>0.8970</PDBx:U11>
         <PDBx:U12>-0.0156</PDBx:U12>
         <PDBx:U13>0.1996</PDBx:U13>
         <PDBx:U22>0.4451</PDBx:U22>
         <PDBx:U23>0.0922</PDBx:U23>
         <PDBx:U33>0.6659</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="793">
         <PDBx:U11>0.8231</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>0.1851</PDBx:U13>
         <PDBx:U22>0.4074</PDBx:U22>
         <PDBx:U23>0.0819</PDBx:U23>
         <PDBx:U33>0.5961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="794">
         <PDBx:U11>0.9963</PDBx:U11>
         <PDBx:U12>0.0034</PDBx:U12>
         <PDBx:U13>0.2016</PDBx:U13>
         <PDBx:U22>0.5283</PDBx:U22>
         <PDBx:U23>0.1232</PDBx:U23>
         <PDBx:U33>0.7537</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="795">
         <PDBx:U11>0.7913</PDBx:U11>
         <PDBx:U12>-0.0694</PDBx:U12>
         <PDBx:U13>0.2075</PDBx:U13>
         <PDBx:U22>0.3519</PDBx:U22>
         <PDBx:U23>0.0270</PDBx:U23>
         <PDBx:U33>0.5869</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="796">
         <PDBx:U11>0.8086</PDBx:U11>
         <PDBx:U12>-0.0832</PDBx:U12>
         <PDBx:U13>0.2171</PDBx:U13>
         <PDBx:U22>0.3488</PDBx:U22>
         <PDBx:U23>0.0107</PDBx:U23>
         <PDBx:U33>0.6092</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="797">
         <PDBx:U11>0.8429</PDBx:U11>
         <PDBx:U12>-0.0684</PDBx:U12>
         <PDBx:U13>0.2207</PDBx:U13>
         <PDBx:U22>0.3624</PDBx:U22>
         <PDBx:U23>0.0078</PDBx:U23>
         <PDBx:U33>0.6420</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="798">
         <PDBx:U11>0.8118</PDBx:U11>
         <PDBx:U12>-0.0510</PDBx:U12>
         <PDBx:U13>0.2123</PDBx:U13>
         <PDBx:U22>0.3484</PDBx:U22>
         <PDBx:U23>0.0117</PDBx:U23>
         <PDBx:U33>0.6105</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="799">
         <PDBx:U11>0.7992</PDBx:U11>
         <PDBx:U12>-0.1027</PDBx:U12>
         <PDBx:U13>0.2107</PDBx:U13>
         <PDBx:U22>0.3762</PDBx:U22>
         <PDBx:U23>-0.0111</PDBx:U23>
         <PDBx:U33>0.6111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="800">
         <PDBx:U11>0.7464</PDBx:U11>
         <PDBx:U12>-0.1168</PDBx:U12>
         <PDBx:U13>0.2072</PDBx:U13>
         <PDBx:U22>0.3496</PDBx:U22>
         <PDBx:U23>-0.0112</PDBx:U23>
         <PDBx:U33>0.5631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="801">
         <PDBx:U11>0.6838</PDBx:U11>
         <PDBx:U12>-0.1321</PDBx:U12>
         <PDBx:U13>0.2004</PDBx:U13>
         <PDBx:U22>0.3244</PDBx:U22>
         <PDBx:U23>-0.0315</PDBx:U23>
         <PDBx:U33>0.5134</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="802">
         <PDBx:U11>0.8349</PDBx:U11>
         <PDBx:U12>-0.1310</PDBx:U12>
         <PDBx:U13>0.2201</PDBx:U13>
         <PDBx:U22>0.4094</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>0.6480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="803">
         <PDBx:U11>0.9310</PDBx:U11>
         <PDBx:U12>-0.0761</PDBx:U12>
         <PDBx:U13>0.2339</PDBx:U13>
         <PDBx:U22>0.4124</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.7294</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="804">
         <PDBx:U11>0.9406</PDBx:U11>
         <PDBx:U12>-0.0648</PDBx:U12>
         <PDBx:U13>0.2391</PDBx:U13>
         <PDBx:U22>0.4013</PDBx:U22>
         <PDBx:U23>-0.0068</PDBx:U23>
         <PDBx:U33>0.7391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="805">
         <PDBx:U11>0.9465</PDBx:U11>
         <PDBx:U12>-0.0859</PDBx:U12>
         <PDBx:U13>0.2389</PDBx:U13>
         <PDBx:U22>0.4223</PDBx:U22>
         <PDBx:U23>-0.0338</PDBx:U23>
         <PDBx:U33>0.7524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="806">
         <PDBx:U11>0.9162</PDBx:U11>
         <PDBx:U12>-0.1087</PDBx:U12>
         <PDBx:U13>0.2366</PDBx:U13>
         <PDBx:U22>0.4125</PDBx:U22>
         <PDBx:U23>-0.0444</PDBx:U23>
         <PDBx:U33>0.7268</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="807">
         <PDBx:U11>1.0357</PDBx:U11>
         <PDBx:U12>-0.0541</PDBx:U12>
         <PDBx:U13>0.2548</PDBx:U13>
         <PDBx:U22>0.4365</PDBx:U22>
         <PDBx:U23>0.0051</PDBx:U23>
         <PDBx:U33>0.8272</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="808">
         <PDBx:U11>1.0426</PDBx:U11>
         <PDBx:U12>-0.0778</PDBx:U12>
         <PDBx:U13>0.2662</PDBx:U13>
         <PDBx:U22>0.4110</PDBx:U22>
         <PDBx:U23>0.0013</PDBx:U23>
         <PDBx:U33>0.8324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="809">
         <PDBx:U11>0.9868</PDBx:U11>
         <PDBx:U12>-0.1036</PDBx:U12>
         <PDBx:U13>0.2657</PDBx:U13>
         <PDBx:U22>0.3714</PDBx:U22>
         <PDBx:U23>-0.0198</PDBx:U23>
         <PDBx:U33>0.7819</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="810">
         <PDBx:U11>1.1272</PDBx:U11>
         <PDBx:U12>-0.0711</PDBx:U12>
         <PDBx:U13>0.2754</PDBx:U13>
         <PDBx:U22>0.4546</PDBx:U22>
         <PDBx:U23>0.0210</PDBx:U23>
         <PDBx:U33>0.9105</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="811">
         <PDBx:U11>0.8902</PDBx:U11>
         <PDBx:U12>-0.0781</PDBx:U12>
         <PDBx:U13>0.2409</PDBx:U13>
         <PDBx:U22>0.3587</PDBx:U22>
         <PDBx:U23>-0.0443</PDBx:U23>
         <PDBx:U33>0.6975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="812">
         <PDBx:U11>0.8507</PDBx:U11>
         <PDBx:U12>-0.0978</PDBx:U12>
         <PDBx:U13>0.2399</PDBx:U13>
         <PDBx:U22>0.3358</PDBx:U22>
         <PDBx:U23>-0.0695</PDBx:U23>
         <PDBx:U33>0.6640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="813">
         <PDBx:U11>0.9348</PDBx:U11>
         <PDBx:U12>-0.1240</PDBx:U12>
         <PDBx:U13>0.2508</PDBx:U13>
         <PDBx:U22>0.3956</PDBx:U22>
         <PDBx:U23>-0.0831</PDBx:U23>
         <PDBx:U33>0.7468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="814">
         <PDBx:U11>0.9249</PDBx:U11>
         <PDBx:U12>-0.1469</PDBx:U12>
         <PDBx:U13>0.2468</PDBx:U13>
         <PDBx:U22>0.4154</PDBx:U22>
         <PDBx:U23>-0.1005</PDBx:U23>
         <PDBx:U33>0.7425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="815">
         <PDBx:U11>0.8760</PDBx:U11>
         <PDBx:U12>-0.0839</PDBx:U12>
         <PDBx:U13>0.2430</PDBx:U13>
         <PDBx:U22>0.3478</PDBx:U22>
         <PDBx:U23>-0.0786</PDBx:U23>
         <PDBx:U33>0.6894</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="816">
         <PDBx:U11>0.9227</PDBx:U11>
         <PDBx:U12>-0.0743</PDBx:U12>
         <PDBx:U13>0.2604</PDBx:U13>
         <PDBx:U22>0.3317</PDBx:U22>
         <PDBx:U23>-0.0794</PDBx:U23>
         <PDBx:U33>0.7292</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="817">
         <PDBx:U11>0.9710</PDBx:U11>
         <PDBx:U12>-0.0575</PDBx:U12>
         <PDBx:U13>0.2628</PDBx:U13>
         <PDBx:U22>0.3720</PDBx:U22>
         <PDBx:U23>-0.0905</PDBx:U23>
         <PDBx:U33>0.7787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="818">
         <PDBx:U11>0.9257</PDBx:U11>
         <PDBx:U12>-0.0764</PDBx:U12>
         <PDBx:U13>0.2555</PDBx:U13>
         <PDBx:U22>0.3628</PDBx:U22>
         <PDBx:U23>-0.1152</PDBx:U23>
         <PDBx:U33>0.7384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="819">
         <PDBx:U11>1.0249</PDBx:U11>
         <PDBx:U12>-0.0963</PDBx:U12>
         <PDBx:U13>0.2636</PDBx:U13>
         <PDBx:U22>0.4454</PDBx:U22>
         <PDBx:U23>-0.1400</PDBx:U23>
         <PDBx:U33>0.8353</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="820">
         <PDBx:U11>0.9881</PDBx:U11>
         <PDBx:U12>-0.1127</PDBx:U12>
         <PDBx:U13>0.2555</PDBx:U13>
         <PDBx:U22>0.4484</PDBx:U22>
         <PDBx:U23>-0.1602</PDBx:U23>
         <PDBx:U33>0.8023</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="821">
         <PDBx:U11>1.0949</PDBx:U11>
         <PDBx:U12>-0.1006</PDBx:U12>
         <PDBx:U13>0.2797</PDBx:U13>
         <PDBx:U22>0.4582</PDBx:U22>
         <PDBx:U23>-0.1444</PDBx:U23>
         <PDBx:U33>0.8984</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="822">
         <PDBx:U11>1.0047</PDBx:U11>
         <PDBx:U12>-0.1208</PDBx:U12>
         <PDBx:U13>0.2646</PDBx:U13>
         <PDBx:U22>0.4116</PDBx:U22>
         <PDBx:U23>-0.0740</PDBx:U23>
         <PDBx:U33>0.8095</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="823">
         <PDBx:U11>1.0767</PDBx:U11>
         <PDBx:U12>-0.1468</PDBx:U12>
         <PDBx:U13>0.2763</PDBx:U13>
         <PDBx:U22>0.4522</PDBx:U22>
         <PDBx:U23>-0.0852</PDBx:U23>
         <PDBx:U33>0.8792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="824">
         <PDBx:U11>1.0042</PDBx:U11>
         <PDBx:U12>-0.1723</PDBx:U12>
         <PDBx:U13>0.2693</PDBx:U13>
         <PDBx:U22>0.4210</PDBx:U22>
         <PDBx:U23>-0.0905</PDBx:U23>
         <PDBx:U33>0.8126</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="825">
         <PDBx:U11>1.0299</PDBx:U11>
         <PDBx:U12>-0.1993</PDBx:U12>
         <PDBx:U13>0.2735</PDBx:U13>
         <PDBx:U22>0.4486</PDBx:U22>
         <PDBx:U23>-0.1097</PDBx:U23>
         <PDBx:U33>0.8404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="826">
         <PDBx:U11>1.1951</PDBx:U11>
         <PDBx:U12>-0.1376</PDBx:U12>
         <PDBx:U13>0.2896</PDBx:U13>
         <PDBx:U22>0.5105</PDBx:U22>
         <PDBx:U23>-0.0658</PDBx:U23>
         <PDBx:U33>0.9897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="827">
         <PDBx:U11>1.3523</PDBx:U11>
         <PDBx:U12>-0.1588</PDBx:U12>
         <PDBx:U13>0.3055</PDBx:U13>
         <PDBx:U22>0.6141</PDBx:U22>
         <PDBx:U23>-0.0801</PDBx:U23>
         <PDBx:U33>1.1427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="828">
         <PDBx:U11>1.3987</PDBx:U11>
         <PDBx:U12>-0.1736</PDBx:U12>
         <PDBx:U13>0.3086</PDBx:U13>
         <PDBx:U22>0.6592</PDBx:U22>
         <PDBx:U23>-0.1062</PDBx:U23>
         <PDBx:U33>1.1898</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="829">
         <PDBx:U11>1.4687</PDBx:U11>
         <PDBx:U12>-0.1616</PDBx:U12>
         <PDBx:U13>0.3157</PDBx:U13>
         <PDBx:U22>0.6851</PDBx:U22>
         <PDBx:U23>-0.0628</PDBx:U23>
         <PDBx:U33>1.2540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="830">
         <PDBx:U11>0.9382</PDBx:U11>
         <PDBx:U12>-0.1632</PDBx:U12>
         <PDBx:U13>0.2588</PDBx:U13>
         <PDBx:U22>0.3888</PDBx:U22>
         <PDBx:U23>-0.0743</PDBx:U23>
         <PDBx:U33>0.7496</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="831">
         <PDBx:U11>0.9761</PDBx:U11>
         <PDBx:U12>-0.1827</PDBx:U12>
         <PDBx:U13>0.2521</PDBx:U13>
         <PDBx:U22>0.4660</PDBx:U22>
         <PDBx:U23>-0.0772</PDBx:U23>
         <PDBx:U33>0.7944</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="832">
         <PDBx:U11>0.9322</PDBx:U11>
         <PDBx:U12>-0.1910</PDBx:U12>
         <PDBx:U13>0.2396</PDBx:U13>
         <PDBx:U22>0.4782</PDBx:U22>
         <PDBx:U23>-0.0940</PDBx:U23>
         <PDBx:U33>0.7602</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="833">
         <PDBx:U11>0.9773</PDBx:U11>
         <PDBx:U12>-0.2118</PDBx:U12>
         <PDBx:U13>0.2363</PDBx:U13>
         <PDBx:U22>0.5538</PDBx:U22>
         <PDBx:U23>-0.1033</PDBx:U23>
         <PDBx:U33>0.8126</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="834">
         <PDBx:U11>0.9760</PDBx:U11>
         <PDBx:U12>-0.1692</PDBx:U12>
         <PDBx:U13>0.2463</PDBx:U13>
         <PDBx:U22>0.4783</PDBx:U22>
         <PDBx:U23>-0.0547</PDBx:U23>
         <PDBx:U33>0.7932</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="835">
         <PDBx:U11>1.0829</PDBx:U11>
         <PDBx:U12>-0.1673</PDBx:U12>
         <PDBx:U13>0.2582</PDBx:U13>
         <PDBx:U22>0.5372</PDBx:U22>
         <PDBx:U23>-0.0352</PDBx:U23>
         <PDBx:U33>0.8918</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="836">
         <PDBx:U11>1.1235</PDBx:U11>
         <PDBx:U12>-0.1443</PDBx:U12>
         <PDBx:U13>0.2522</PDBx:U13>
         <PDBx:U22>0.5841</PDBx:U22>
         <PDBx:U23>-0.0105</PDBx:U23>
         <PDBx:U33>0.9272</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="837">
         <PDBx:U11>1.1852</PDBx:U11>
         <PDBx:U12>-0.1250</PDBx:U12>
         <PDBx:U13>0.2415</PDBx:U13>
         <PDBx:U22>0.6714</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.9891</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="838">
         <PDBx:U11>1.1472</PDBx:U11>
         <PDBx:U12>-0.1480</PDBx:U12>
         <PDBx:U13>0.2590</PDBx:U13>
         <PDBx:U22>0.5856</PDBx:U22>
         <PDBx:U23>0.0090</PDBx:U23>
         <PDBx:U33>0.9457</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="839">
         <PDBx:U11>0.8221</PDBx:U11>
         <PDBx:U12>-0.1747</PDBx:U12>
         <PDBx:U13>0.2325</PDBx:U13>
         <PDBx:U22>0.3825</PDBx:U22>
         <PDBx:U23>-0.0964</PDBx:U23>
         <PDBx:U33>0.6509</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="840">
         <PDBx:U11>0.8317</PDBx:U11>
         <PDBx:U12>-0.1815</PDBx:U12>
         <PDBx:U13>0.2205</PDBx:U13>
         <PDBx:U22>0.4427</PDBx:U22>
         <PDBx:U23>-0.1095</PDBx:U23>
         <PDBx:U33>0.6694</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="841">
         <PDBx:U11>0.8819</PDBx:U11>
         <PDBx:U12>-0.2085</PDBx:U12>
         <PDBx:U13>0.2257</PDBx:U13>
         <PDBx:U22>0.4973</PDBx:U22>
         <PDBx:U23>-0.1321</PDBx:U23>
         <PDBx:U33>0.7216</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="842">
         <PDBx:U11>0.8613</PDBx:U11>
         <PDBx:U12>-0.2206</PDBx:U12>
         <PDBx:U13>0.2164</PDBx:U13>
         <PDBx:U22>0.5233</PDBx:U22>
         <PDBx:U23>-0.1426</PDBx:U23>
         <PDBx:U33>0.7091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="843">
         <PDBx:U11>0.9563</PDBx:U11>
         <PDBx:U12>-0.2182</PDBx:U12>
         <PDBx:U13>0.2407</PDBx:U13>
         <PDBx:U22>0.5220</PDBx:U22>
         <PDBx:U23>-0.1395</PDBx:U23>
         <PDBx:U33>0.7881</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="844">
         <PDBx:U11>1.0094</PDBx:U11>
         <PDBx:U12>-0.2463</PDBx:U12>
         <PDBx:U13>0.2474</PDBx:U13>
         <PDBx:U22>0.5725</PDBx:U22>
         <PDBx:U23>-0.1633</PDBx:U23>
         <PDBx:U33>0.8406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="845">
         <PDBx:U11>0.9718</PDBx:U11>
         <PDBx:U12>-0.2726</PDBx:U12>
         <PDBx:U13>0.2459</PDBx:U13>
         <PDBx:U22>0.5621</PDBx:U22>
         <PDBx:U23>-0.1680</PDBx:U23>
         <PDBx:U33>0.8091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="846">
         <PDBx:U11>0.9631</PDBx:U11>
         <PDBx:U12>-0.2983</PDBx:U12>
         <PDBx:U13>0.2469</PDBx:U13>
         <PDBx:U22>0.5721</PDBx:U22>
         <PDBx:U23>-0.1881</PDBx:U23>
         <PDBx:U33>0.8022</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="847">
         <PDBx:U11>1.1048</PDBx:U11>
         <PDBx:U12>-0.2492</PDBx:U12>
         <PDBx:U13>0.2648</PDBx:U13>
         <PDBx:U22>0.5995</PDBx:U22>
         <PDBx:U23>-0.1701</PDBx:U23>
         <PDBx:U33>0.9252</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="848">
         <PDBx:U11>1.1428</PDBx:U11>
         <PDBx:U12>-0.2241</PDBx:U12>
         <PDBx:U13>0.2675</PDBx:U13>
         <PDBx:U22>0.6105</PDBx:U22>
         <PDBx:U23>-0.1694</PDBx:U23>
         <PDBx:U33>0.9582</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="849">
         <PDBx:U11>1.2578</PDBx:U11>
         <PDBx:U12>-0.2251</PDBx:U12>
         <PDBx:U13>0.2857</PDBx:U13>
         <PDBx:U22>0.6531</PDBx:U22>
         <PDBx:U23>-0.1767</PDBx:U23>
         <PDBx:U33>1.0631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="850">
         <PDBx:U11>1.3101</PDBx:U11>
         <PDBx:U12>-0.1974</PDBx:U12>
         <PDBx:U13>0.2886</PDBx:U13>
         <PDBx:U22>0.6800</PDBx:U22>
         <PDBx:U23>-0.1770</PDBx:U23>
         <PDBx:U33>1.1116</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="851">
         <PDBx:U11>1.2921</PDBx:U11>
         <PDBx:U12>-0.1654</PDBx:U12>
         <PDBx:U13>0.2814</PDBx:U13>
         <PDBx:U22>0.6702</PDBx:U22>
         <PDBx:U23>-0.1495</PDBx:U23>
         <PDBx:U33>1.0960</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="852">
         <PDBx:U11>0.9497</PDBx:U11>
         <PDBx:U12>-0.2668</PDBx:U12>
         <PDBx:U13>0.2435</PDBx:U13>
         <PDBx:U22>0.5444</PDBx:U22>
         <PDBx:U23>-0.1501</PDBx:U23>
         <PDBx:U33>0.7902</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="853">
         <PDBx:U11>1.0090</PDBx:U11>
         <PDBx:U12>-0.2901</PDBx:U12>
         <PDBx:U13>0.2419</PDBx:U13>
         <PDBx:U22>0.6314</PDBx:U22>
         <PDBx:U23>-0.1526</PDBx:U23>
         <PDBx:U33>0.8576</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="854">
         <PDBx:U11>0.9541</PDBx:U11>
         <PDBx:U12>-0.3002</PDBx:U12>
         <PDBx:U13>0.2285</PDBx:U13>
         <PDBx:U22>0.6418</PDBx:U22>
         <PDBx:U23>-0.1650</PDBx:U23>
         <PDBx:U33>0.8136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="855">
         <PDBx:U11>0.7937</PDBx:U11>
         <PDBx:U12>-0.3264</PDBx:U12>
         <PDBx:U13>0.2282</PDBx:U13>
         <PDBx:U22>0.5076</PDBx:U22>
         <PDBx:U23>-0.1760</PDBx:U23>
         <PDBx:U33>0.6599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="856">
         <PDBx:U11>0.9786</PDBx:U11>
         <PDBx:U12>-0.2781</PDBx:U12>
         <PDBx:U13>0.2398</PDBx:U13>
         <PDBx:U22>0.6022</PDBx:U22>
         <PDBx:U23>-0.1303</PDBx:U23>
         <PDBx:U33>0.8300</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="857">
         <PDBx:U11>1.3897</PDBx:U11>
         <PDBx:U12>-0.2680</PDBx:U12>
         <PDBx:U13>0.2548</PDBx:U13>
         <PDBx:U22>0.9417</PDBx:U22>
         <PDBx:U23>-0.1109</PDBx:U23>
         <PDBx:U33>1.2286</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="858">
         <PDBx:U11>0.8759</PDBx:U11>
         <PDBx:U12>-0.2798</PDBx:U12>
         <PDBx:U13>0.2170</PDBx:U13>
         <PDBx:U22>0.5908</PDBx:U22>
         <PDBx:U23>-0.1618</PDBx:U23>
         <PDBx:U33>0.7379</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="859">
         <PDBx:U11>0.8184</PDBx:U11>
         <PDBx:U12>-0.2855</PDBx:U12>
         <PDBx:U13>0.2030</PDBx:U13>
         <PDBx:U22>0.5943</PDBx:U22>
         <PDBx:U23>-0.1696</PDBx:U23>
         <PDBx:U33>0.6909</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="860">
         <PDBx:U11>0.8401</PDBx:U11>
         <PDBx:U12>-0.2853</PDBx:U12>
         <PDBx:U13>0.2008</PDBx:U13>
         <PDBx:U22>0.6247</PDBx:U22>
         <PDBx:U23>-0.1825</PDBx:U23>
         <PDBx:U33>0.7088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="861">
         <PDBx:U11>0.8170</PDBx:U11>
         <PDBx:U12>-0.2648</PDBx:U12>
         <PDBx:U13>0.2009</PDBx:U13>
         <PDBx:U22>0.5815</PDBx:U22>
         <PDBx:U23>-0.1762</PDBx:U23>
         <PDBx:U33>0.6808</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="862">
         <PDBx:U11>0.7270</PDBx:U11>
         <PDBx:U12>-0.2637</PDBx:U12>
         <PDBx:U13>0.1892</PDBx:U13>
         <PDBx:U22>0.5343</PDBx:U22>
         <PDBx:U23>-0.1531</PDBx:U23>
         <PDBx:U33>0.6084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="863">
         <PDBx:U11>0.7269</PDBx:U11>
         <PDBx:U12>-0.2697</PDBx:U12>
         <PDBx:U13>0.1746</PDBx:U13>
         <PDBx:U22>0.5948</PDBx:U22>
         <PDBx:U23>-0.1593</PDBx:U23>
         <PDBx:U33>0.6205</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="864">
         <PDBx:U11>0.7226</PDBx:U11>
         <PDBx:U12>-0.2633</PDBx:U12>
         <PDBx:U13>0.1922</PDBx:U13>
         <PDBx:U22>0.5212</PDBx:U22>
         <PDBx:U23>-0.1407</PDBx:U23>
         <PDBx:U33>0.6076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="865">
         <PDBx:U11>0.8186</PDBx:U11>
         <PDBx:U12>-0.3091</PDBx:U12>
         <PDBx:U13>0.1986</PDBx:U13>
         <PDBx:U22>0.6366</PDBx:U22>
         <PDBx:U23>-0.2004</PDBx:U23>
         <PDBx:U33>0.6898</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="866">
         <PDBx:U11>0.7982</PDBx:U11>
         <PDBx:U12>-0.3135</PDBx:U12>
         <PDBx:U13>0.1973</PDBx:U13>
         <PDBx:U22>0.6287</PDBx:U22>
         <PDBx:U23>-0.2152</PDBx:U23>
         <PDBx:U33>0.6651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="867">
         <PDBx:U11>0.7324</PDBx:U11>
         <PDBx:U12>-0.2894</PDBx:U12>
         <PDBx:U13>0.1845</PDBx:U13>
         <PDBx:U22>0.5891</PDBx:U22>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.2060</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="871">
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         <PDBx:U12>-0.2586</PDBx:U12>
         <PDBx:U13>0.1773</PDBx:U13>
         <PDBx:U22>0.6040</PDBx:U22>
         <PDBx:U23>-0.1967</PDBx:U23>
         <PDBx:U33>0.6191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.6881</PDBx:U11>
         <PDBx:U12>-0.2312</PDBx:U12>
         <PDBx:U13>0.1735</PDBx:U13>
         <PDBx:U22>0.5233</PDBx:U22>
         <PDBx:U23>-0.1743</PDBx:U23>
         <PDBx:U33>0.5595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.1652</PDBx:U13>
         <PDBx:U22>0.4804</PDBx:U22>
         <PDBx:U23>-0.1662</PDBx:U23>
         <PDBx:U33>0.5079</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="874">
         <PDBx:U11>0.7376</PDBx:U11>
         <PDBx:U12>-0.1924</PDBx:U12>
         <PDBx:U13>0.2926</PDBx:U13>
         <PDBx:U22>0.4144</PDBx:U22>
         <PDBx:U23>-0.1537</PDBx:U23>
         <PDBx:U33>0.6056</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="875">
         <PDBx:U11>0.7035</PDBx:U11>
         <PDBx:U12>-0.1811</PDBx:U12>
         <PDBx:U13>0.2789</PDBx:U13>
         <PDBx:U22>0.3791</PDBx:U22>
         <PDBx:U23>-0.1394</PDBx:U23>
         <PDBx:U33>0.5559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="876">
         <PDBx:U11>0.7529</PDBx:U11>
         <PDBx:U12>-0.1708</PDBx:U12>
         <PDBx:U13>0.2858</PDBx:U13>
         <PDBx:U22>0.3936</PDBx:U22>
         <PDBx:U23>-0.1261</PDBx:U23>
         <PDBx:U33>0.5739</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="877">
         <PDBx:U11>0.6600</PDBx:U11>
         <PDBx:U12>-0.1597</PDBx:U12>
         <PDBx:U13>0.2641</PDBx:U13>
         <PDBx:U22>0.3060</PDBx:U22>
         <PDBx:U23>-0.1132</PDBx:U23>
         <PDBx:U33>0.4708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="878">
         <PDBx:U11>0.7167</PDBx:U11>
         <PDBx:U12>-0.1854</PDBx:U12>
         <PDBx:U13>0.2957</PDBx:U13>
         <PDBx:U22>0.3846</PDBx:U22>
         <PDBx:U23>-0.1438</PDBx:U23>
         <PDBx:U33>0.5669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="879">
         <PDBx:U11>0.7721</PDBx:U11>
         <PDBx:U12>-0.1774</PDBx:U12>
         <PDBx:U13>0.2720</PDBx:U13>
         <PDBx:U22>0.4583</PDBx:U22>
         <PDBx:U23>-0.1338</PDBx:U23>
         <PDBx:U33>0.6198</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="880">
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         <PDBx:U12>-0.1839</PDBx:U12>
         <PDBx:U13>0.2949</PDBx:U13>
         <PDBx:U22>0.6158</PDBx:U22>
         <PDBx:U23>-0.1404</PDBx:U23>
         <PDBx:U33>0.7836</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:U11>0.7218</PDBx:U11>
         <PDBx:U12>-0.1824</PDBx:U12>
         <PDBx:U13>0.3327</PDBx:U13>
         <PDBx:U22>0.3328</PDBx:U22>
         <PDBx:U23>-0.1347</PDBx:U23>
         <PDBx:U33>0.5189</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.8104</PDBx:U11>
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         <PDBx:U13>0.3165</PDBx:U13>
         <PDBx:U22>0.4141</PDBx:U22>
         <PDBx:U23>-0.1295</PDBx:U23>
         <PDBx:U33>0.6174</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>-0.1166</PDBx:U23>
         <PDBx:U33>0.6289</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="884">
         <PDBx:U11>0.7959</PDBx:U11>
         <PDBx:U12>-0.1524</PDBx:U12>
         <PDBx:U13>0.2965</PDBx:U13>
         <PDBx:U22>0.3812</PDBx:U22>
         <PDBx:U23>-0.1085</PDBx:U23>
         <PDBx:U33>0.5803</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="885">
         <PDBx:U11>0.8093</PDBx:U11>
         <PDBx:U12>-0.1380</PDBx:U12>
         <PDBx:U13>0.2879</PDBx:U13>
         <PDBx:U22>0.3789</PDBx:U22>
         <PDBx:U23>-0.0951</PDBx:U23>
         <PDBx:U33>0.5768</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="886">
         <PDBx:U11>0.9641</PDBx:U11>
         <PDBx:U12>-0.1656</PDBx:U12>
         <PDBx:U13>0.3674</PDBx:U13>
         <PDBx:U22>0.4838</PDBx:U22>
         <PDBx:U23>-0.1219</PDBx:U23>
         <PDBx:U33>0.7290</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="887">
         <PDBx:U11>0.9707</PDBx:U11>
         <PDBx:U12>-0.1757</PDBx:U12>
         <PDBx:U13>0.3675</PDBx:U13>
         <PDBx:U22>0.5056</PDBx:U22>
         <PDBx:U23>-0.1331</PDBx:U23>
         <PDBx:U33>0.7545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="888">
         <PDBx:U11>1.0140</PDBx:U11>
         <PDBx:U12>-0.1479</PDBx:U12>
         <PDBx:U13>0.3809</PDBx:U13>
         <PDBx:U22>0.4864</PDBx:U22>
         <PDBx:U23>-0.1060</PDBx:U23>
         <PDBx:U33>0.7473</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="889">
         <PDBx:U11>0.6856</PDBx:U11>
         <PDBx:U12>-0.1603</PDBx:U12>
         <PDBx:U13>0.2810</PDBx:U13>
         <PDBx:U22>0.3045</PDBx:U22>
         <PDBx:U23>-0.1169</PDBx:U23>
         <PDBx:U33>0.4935</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="890">
         <PDBx:U11>0.6781</PDBx:U11>
         <PDBx:U12>-0.1535</PDBx:U12>
         <PDBx:U13>0.2545</PDBx:U13>
         <PDBx:U22>0.3176</PDBx:U22>
         <PDBx:U23>-0.1107</PDBx:U23>
         <PDBx:U33>0.4920</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="891">
         <PDBx:U11>0.6076</PDBx:U11>
         <PDBx:U12>-0.1440</PDBx:U12>
         <PDBx:U13>0.2208</PDBx:U13>
         <PDBx:U22>0.2747</PDBx:U22>
         <PDBx:U23>-0.0998</PDBx:U23>
         <PDBx:U33>0.4251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="892">
         <PDBx:U11>0.6295</PDBx:U11>
         <PDBx:U12>-0.1339</PDBx:U12>
         <PDBx:U13>0.2043</PDBx:U13>
         <PDBx:U22>0.2989</PDBx:U22>
         <PDBx:U23>-0.0903</PDBx:U23>
         <PDBx:U33>0.4425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="893">
         <PDBx:U11>0.7201</PDBx:U11>
         <PDBx:U12>-0.1643</PDBx:U12>
         <PDBx:U13>0.2462</PDBx:U13>
         <PDBx:U22>0.3868</PDBx:U22>
         <PDBx:U23>-0.1220</PDBx:U23>
         <PDBx:U33>0.5544</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="894">
         <PDBx:U11>0.8147</PDBx:U11>
         <PDBx:U12>-0.1736</PDBx:U12>
         <PDBx:U13>0.2759</PDBx:U13>
         <PDBx:U22>0.4544</PDBx:U22>
         <PDBx:U23>-0.1324</PDBx:U23>
         <PDBx:U33>0.6439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="895">
         <PDBx:U11>0.8888</PDBx:U11>
         <PDBx:U12>-0.1871</PDBx:U12>
         <PDBx:U13>0.3029</PDBx:U13>
         <PDBx:U22>0.5167</PDBx:U22>
         <PDBx:U23>-0.1463</PDBx:U23>
         <PDBx:U33>0.7230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="896">
         <PDBx:U11>0.8956</PDBx:U11>
         <PDBx:U12>-0.1930</PDBx:U12>
         <PDBx:U13>0.2906</PDBx:U13>
         <PDBx:U22>0.5516</PDBx:U22>
         <PDBx:U23>-0.1530</PDBx:U23>
         <PDBx:U33>0.7482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="897">
         <PDBx:U11>0.9599</PDBx:U11>
         <PDBx:U12>-0.1915</PDBx:U12>
         <PDBx:U13>0.3374</PDBx:U13>
         <PDBx:U22>0.5492</PDBx:U22>
         <PDBx:U23>-0.1507</PDBx:U23>
         <PDBx:U33>0.7810</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="898">
         <PDBx:U11>0.6284</PDBx:U11>
         <PDBx:U12>-0.1475</PDBx:U12>
         <PDBx:U13>0.2123</PDBx:U13>
         <PDBx:U22>0.3159</PDBx:U22>
         <PDBx:U23>-0.1019</PDBx:U23>
         <PDBx:U33>0.4554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="899">
         <PDBx:U11>0.6272</PDBx:U11>
         <PDBx:U12>-0.1399</PDBx:U12>
         <PDBx:U13>0.1836</PDBx:U13>
         <PDBx:U22>0.3391</PDBx:U22>
         <PDBx:U23>-0.0924</PDBx:U23>
         <PDBx:U33>0.4573</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="900">
         <PDBx:U11>0.6193</PDBx:U11>
         <PDBx:U12>-0.1309</PDBx:U12>
         <PDBx:U13>0.1889</PDBx:U13>
         <PDBx:U22>0.3015</PDBx:U22>
         <PDBx:U23>-0.0821</PDBx:U23>
         <PDBx:U33>0.4232</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="901">
         <PDBx:U11>0.5450</PDBx:U11>
         <PDBx:U12>-0.1218</PDBx:U12>
         <PDBx:U13>0.1665</PDBx:U13>
         <PDBx:U22>0.2358</PDBx:U22>
         <PDBx:U23>-0.0720</PDBx:U23>
         <PDBx:U33>0.3448</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="902">
         <PDBx:U11>0.6078</PDBx:U11>
         <PDBx:U12>-0.1457</PDBx:U12>
         <PDBx:U13>0.1755</PDBx:U13>
         <PDBx:U22>0.3475</PDBx:U22>
         <PDBx:U23>-0.0981</PDBx:U23>
         <PDBx:U33>0.4568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="903">
         <PDBx:U11>0.5462</PDBx:U11>
         <PDBx:U12>-0.1531</PDBx:U12>
         <PDBx:U13>0.1718</PDBx:U13>
         <PDBx:U22>0.3082</PDBx:U22>
         <PDBx:U23>-0.1087</PDBx:U23>
         <PDBx:U33>0.4195</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="904">
         <PDBx:U11>0.5957</PDBx:U11>
         <PDBx:U12>-0.1381</PDBx:U12>
         <PDBx:U13>0.1466</PDBx:U13>
         <PDBx:U22>0.3611</PDBx:U22>
         <PDBx:U23>-0.0882</PDBx:U23>
         <PDBx:U33>0.4492</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="905">
         <PDBx:U11>0.5263</PDBx:U11>
         <PDBx:U12>-0.1483</PDBx:U12>
         <PDBx:U13>0.1472</PDBx:U13>
         <PDBx:U22>0.3100</PDBx:U22>
         <PDBx:U23>-0.1036</PDBx:U23>
         <PDBx:U33>0.4078</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="906">
         <PDBx:U11>0.6019</PDBx:U11>
         <PDBx:U12>-0.1331</PDBx:U12>
         <PDBx:U13>0.2194</PDBx:U13>
         <PDBx:U22>0.2470</PDBx:U22>
         <PDBx:U23>-0.0847</PDBx:U23>
         <PDBx:U33>0.3872</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="907">
         <PDBx:U11>0.6585</PDBx:U11>
         <PDBx:U12>-0.1223</PDBx:U12>
         <PDBx:U13>0.2285</PDBx:U13>
         <PDBx:U22>0.2653</PDBx:U22>
         <PDBx:U23>-0.0741</PDBx:U23>
         <PDBx:U33>0.4128</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="908">
         <PDBx:U11>0.6778</PDBx:U11>
         <PDBx:U12>-0.1075</PDBx:U12>
         <PDBx:U13>0.2212</PDBx:U13>
         <PDBx:U22>0.2666</PDBx:U22>
         <PDBx:U23>-0.0634</PDBx:U23>
         <PDBx:U33>0.4217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="909">
         <PDBx:U11>0.7090</PDBx:U11>
         <PDBx:U12>-0.0956</PDBx:U12>
         <PDBx:U13>0.2046</PDBx:U13>
         <PDBx:U22>0.2923</PDBx:U22>
         <PDBx:U23>-0.0525</PDBx:U23>
         <PDBx:U33>0.4407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="910">
         <PDBx:U11>0.7316</PDBx:U11>
         <PDBx:U12>-0.1255</PDBx:U12>
         <PDBx:U13>0.2684</PDBx:U13>
         <PDBx:U22>0.2941</PDBx:U22>
         <PDBx:U23>-0.0782</PDBx:U23>
         <PDBx:U33>0.4653</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="911">
         <PDBx:U11>0.7680</PDBx:U11>
         <PDBx:U12>-0.1338</PDBx:U12>
         <PDBx:U13>0.2762</PDBx:U13>
         <PDBx:U22>0.3334</PDBx:U22>
         <PDBx:U23>-0.0835</PDBx:U23>
         <PDBx:U33>0.4984</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="912">
         <PDBx:U11>0.8318</PDBx:U11>
         <PDBx:U12>-0.1317</PDBx:U12>
         <PDBx:U13>0.3072</PDBx:U13>
         <PDBx:U22>0.3508</PDBx:U22>
         <PDBx:U23>-0.0818</PDBx:U23>
         <PDBx:U33>0.5320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="913">
         <PDBx:U11>0.7259</PDBx:U11>
         <PDBx:U12>-0.1423</PDBx:U12>
         <PDBx:U13>0.2547</PDBx:U13>
         <PDBx:U22>0.3380</PDBx:U22>
         <PDBx:U23>-0.0898</PDBx:U23>
         <PDBx:U33>0.4829</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="914">
         <PDBx:U11>0.8411</PDBx:U11>
         <PDBx:U12>-0.1403</PDBx:U12>
         <PDBx:U13>0.3166</PDBx:U13>
         <PDBx:U22>0.3614</PDBx:U22>
         <PDBx:U23>-0.0879</PDBx:U23>
         <PDBx:U33>0.5372</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="915">
         <PDBx:U11>0.7832</PDBx:U11>
         <PDBx:U12>-0.1495</PDBx:U12>
         <PDBx:U13>0.2642</PDBx:U13>
         <PDBx:U22>0.3976</PDBx:U22>
         <PDBx:U23>-0.0954</PDBx:U23>
         <PDBx:U33>0.5391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="916">
         <PDBx:U11>0.8012</PDBx:U11>
         <PDBx:U12>-0.1498</PDBx:U12>
         <PDBx:U13>0.2953</PDBx:U13>
         <PDBx:U22>0.3704</PDBx:U22>
         <PDBx:U23>-0.0952</PDBx:U23>
         <PDBx:U33>0.5265</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="917">
         <PDBx:U11>0.6785</PDBx:U11>
         <PDBx:U12>-0.1082</PDBx:U12>
         <PDBx:U13>0.2344</PDBx:U13>
         <PDBx:U22>0.2579</PDBx:U22>
         <PDBx:U23>-0.0670</PDBx:U23>
         <PDBx:U33>0.4284</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="918">
         <PDBx:U11>0.6995</PDBx:U11>
         <PDBx:U12>-0.0935</PDBx:U12>
         <PDBx:U13>0.2312</PDBx:U13>
         <PDBx:U22>0.2612</PDBx:U22>
         <PDBx:U23>-0.0579</PDBx:U23>
         <PDBx:U33>0.4435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="919">
         <PDBx:U11>0.6228</PDBx:U11>
         <PDBx:U12>-0.0891</PDBx:U12>
         <PDBx:U13>0.1929</PDBx:U13>
         <PDBx:U22>0.2226</PDBx:U22>
         <PDBx:U23>-0.0532</PDBx:U23>
         <PDBx:U33>0.3827</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="920">
         <PDBx:U11>0.7182</PDBx:U11>
         <PDBx:U12>-0.0731</PDBx:U12>
         <PDBx:U13>0.1830</PDBx:U13>
         <PDBx:U22>0.3049</PDBx:U22>
         <PDBx:U23>-0.0422</PDBx:U23>
         <PDBx:U33>0.4706</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="921">
         <PDBx:U11>0.7218</PDBx:U11>
         <PDBx:U12>-0.0985</PDBx:U12>
         <PDBx:U13>0.2530</PDBx:U13>
         <PDBx:U22>0.2709</PDBx:U22>
         <PDBx:U23>-0.0652</PDBx:U23>
         <PDBx:U33>0.4721</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="922">
         <PDBx:U11>0.8578</PDBx:U11>
         <PDBx:U12>-0.0984</PDBx:U12>
         <PDBx:U13>0.2951</PDBx:U13>
         <PDBx:U22>0.3579</PDBx:U22>
         <PDBx:U23>-0.0665</PDBx:U23>
         <PDBx:U33>0.5885</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="923">
         <PDBx:U11>0.8160</PDBx:U11>
         <PDBx:U12>-0.0870</PDBx:U12>
         <PDBx:U13>0.3078</PDBx:U13>
         <PDBx:U22>0.2827</PDBx:U22>
         <PDBx:U23>-0.0571</PDBx:U23>
         <PDBx:U33>0.5231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="924">
         <PDBx:U11>0.8757</PDBx:U11>
         <PDBx:U12>-0.1095</PDBx:U12>
         <PDBx:U13>0.3163</PDBx:U13>
         <PDBx:U22>0.3692</PDBx:U22>
         <PDBx:U23>-0.0770</PDBx:U23>
         <PDBx:U33>0.6134</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="925">
         <PDBx:U11>0.6045</PDBx:U11>
         <PDBx:U12>-0.1014</PDBx:U12>
         <PDBx:U13>0.1727</PDBx:U13>
         <PDBx:U22>0.2504</PDBx:U22>
         <PDBx:U23>-0.0606</PDBx:U23>
         <PDBx:U33>0.3875</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="926">
         <PDBx:U11>0.5615</PDBx:U11>
         <PDBx:U12>-0.0985</PDBx:U12>
         <PDBx:U13>0.1385</PDBx:U13>
         <PDBx:U22>0.2450</PDBx:U22>
         <PDBx:U23>-0.0561</PDBx:U23>
         <PDBx:U33>0.3601</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="927">
         <PDBx:U11>0.5443</PDBx:U11>
         <PDBx:U12>-0.0924</PDBx:U12>
         <PDBx:U13>0.1214</PDBx:U13>
         <PDBx:U22>0.2313</PDBx:U22>
         <PDBx:U23>-0.0475</PDBx:U23>
         <PDBx:U33>0.3340</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="928">
         <PDBx:U11>0.5554</PDBx:U11>
         <PDBx:U12>-0.0839</PDBx:U12>
         <PDBx:U13>0.1008</PDBx:U13>
         <PDBx:U22>0.2510</PDBx:U22>
         <PDBx:U23>-0.0401</PDBx:U23>
         <PDBx:U33>0.3476</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="929">
         <PDBx:U11>0.5336</PDBx:U11>
         <PDBx:U12>-0.1095</PDBx:U12>
         <PDBx:U13>0.1245</PDBx:U13>
         <PDBx:U22>0.2601</PDBx:U22>
         <PDBx:U23>-0.0632</PDBx:U23>
         <PDBx:U33>0.3556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="930">
         <PDBx:U11>0.5665</PDBx:U11>
         <PDBx:U12>-0.1165</PDBx:U12>
         <PDBx:U13>0.1369</PDBx:U13>
         <PDBx:U22>0.2929</PDBx:U22>
         <PDBx:U23>-0.0721</PDBx:U23>
         <PDBx:U33>0.3965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="931">
         <PDBx:U11>0.6259</PDBx:U11>
         <PDBx:U12>-0.1239</PDBx:U12>
         <PDBx:U13>0.1161</PDBx:U13>
         <PDBx:U22>0.3980</PDBx:U22>
         <PDBx:U23>-0.0769</PDBx:U23>
         <PDBx:U33>0.4795</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="932">
         <PDBx:U11>0.8391</PDBx:U11>
         <PDBx:U12>-0.1335</PDBx:U12>
         <PDBx:U13>0.1362</PDBx:U13>
         <PDBx:U22>0.5983</PDBx:U22>
         <PDBx:U23>-0.0884</PDBx:U23>
         <PDBx:U33>0.6929</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="933">
         <PDBx:U11>0.5218</PDBx:U11>
         <PDBx:U12>-0.0977</PDBx:U12>
         <PDBx:U13>0.1311</PDBx:U13>
         <PDBx:U22>0.2018</PDBx:U22>
         <PDBx:U23>-0.0494</PDBx:U23>
         <PDBx:U33>0.3015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="934">
         <PDBx:U11>0.5384</PDBx:U11>
         <PDBx:U12>-0.0942</PDBx:U12>
         <PDBx:U13>0.1184</PDBx:U13>
         <PDBx:U22>0.2179</PDBx:U22>
         <PDBx:U23>-0.0426</PDBx:U23>
         <PDBx:U33>0.3050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="935">
         <PDBx:U11>0.6059</PDBx:U11>
         <PDBx:U12>-0.0781</PDBx:U12>
         <PDBx:U13>0.1245</PDBx:U13>
         <PDBx:U22>0.2420</PDBx:U22>
         <PDBx:U23>-0.0321</PDBx:U23>
         <PDBx:U33>0.3464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="936">
         <PDBx:U11>0.5826</PDBx:U11>
         <PDBx:U12>-0.0705</PDBx:U12>
         <PDBx:U13>0.1033</PDBx:U13>
         <PDBx:U22>0.2239</PDBx:U22>
         <PDBx:U23>-0.0239</PDBx:U23>
         <PDBx:U33>0.3191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="937">
         <PDBx:U11>0.6035</PDBx:U11>
         <PDBx:U12>-0.1040</PDBx:U12>
         <PDBx:U13>0.1328</PDBx:U13>
         <PDBx:U22>0.2805</PDBx:U22>
         <PDBx:U23>-0.0485</PDBx:U23>
         <PDBx:U33>0.3638</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="938">
         <PDBx:U11>0.5220</PDBx:U11>
         <PDBx:U12>-0.1146</PDBx:U12>
         <PDBx:U13>0.1232</PDBx:U13>
         <PDBx:U22>0.2427</PDBx:U22>
         <PDBx:U23>-0.0560</PDBx:U23>
         <PDBx:U33>0.3108</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="939">
         <PDBx:U11>0.5451</PDBx:U11>
         <PDBx:U12>-0.1239</PDBx:U12>
         <PDBx:U13>0.1458</PDBx:U13>
         <PDBx:U22>0.2564</PDBx:U22>
         <PDBx:U23>-0.0648</PDBx:U23>
         <PDBx:U33>0.3312</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="940">
         <PDBx:U11>0.4828</PDBx:U11>
         <PDBx:U12>-0.1126</PDBx:U12>
         <PDBx:U13>0.0936</PDBx:U13>
         <PDBx:U22>0.2388</PDBx:U22>
         <PDBx:U23>-0.0493</PDBx:U23>
         <PDBx:U33>0.2828</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="941">
         <PDBx:U11>0.6455</PDBx:U11>
         <PDBx:U12>-0.0708</PDBx:U12>
         <PDBx:U13>0.1548</PDBx:U13>
         <PDBx:U22>0.2378</PDBx:U22>
         <PDBx:U23>-0.0309</PDBx:U23>
         <PDBx:U33>0.3690</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="942">
         <PDBx:U11>0.7300</PDBx:U11>
         <PDBx:U12>-0.0482</PDBx:U12>
         <PDBx:U13>0.1649</PDBx:U13>
         <PDBx:U22>0.2765</PDBx:U22>
         <PDBx:U23>-0.0164</PDBx:U23>
         <PDBx:U33>0.4298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="943">
         <PDBx:U11>0.7258</PDBx:U11>
         <PDBx:U12>-0.0335</PDBx:U12>
         <PDBx:U13>0.1452</PDBx:U13>
         <PDBx:U22>0.2823</PDBx:U22>
         <PDBx:U23>-0.0073</PDBx:U23>
         <PDBx:U33>0.4405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="944">
         <PDBx:U11>0.7147</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>0.1342</PDBx:U13>
         <PDBx:U22>0.2586</PDBx:U22>
         <PDBx:U23>0.0093</PDBx:U23>
         <PDBx:U33>0.4212</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="945">
         <PDBx:U11>0.7817</PDBx:U11>
         <PDBx:U12>-0.0421</PDBx:U12>
         <PDBx:U13>0.2047</PDBx:U13>
         <PDBx:U22>0.2816</PDBx:U22>
         <PDBx:U23>-0.0156</PDBx:U23>
         <PDBx:U33>0.4639</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="946">
         <PDBx:U11>0.7797</PDBx:U11>
         <PDBx:U12>-0.0521</PDBx:U12>
         <PDBx:U13>0.2302</PDBx:U13>
         <PDBx:U22>0.2575</PDBx:U22>
         <PDBx:U23>-0.0217</PDBx:U23>
         <PDBx:U33>0.4421</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="947">
         <PDBx:U11>0.8414</PDBx:U11>
         <PDBx:U12>-0.0510</PDBx:U12>
         <PDBx:U13>0.2705</PDBx:U13>
         <PDBx:U22>0.2797</PDBx:U22>
         <PDBx:U23>-0.0241</PDBx:U23>
         <PDBx:U33>0.4931</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="948">
         <PDBx:U11>0.8118</PDBx:U11>
         <PDBx:U12>-0.0391</PDBx:U12>
         <PDBx:U13>0.2277</PDBx:U13>
         <PDBx:U22>0.2626</PDBx:U22>
         <PDBx:U23>-0.0097</PDBx:U23>
         <PDBx:U33>0.4451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="965">
         <PDBx:U11>0.7673</PDBx:U11>
         <PDBx:U12>-0.0285</PDBx:U12>
         <PDBx:U13>0.0875</PDBx:U13>
         <PDBx:U22>0.3435</PDBx:U22>
         <PDBx:U23>0.0169</PDBx:U23>
         <PDBx:U33>0.4517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="966">
         <PDBx:U11>0.8339</PDBx:U11>
         <PDBx:U12>-0.0153</PDBx:U12>
         <PDBx:U13>0.0901</PDBx:U13>
         <PDBx:U22>0.3731</PDBx:U22>
         <PDBx:U23>0.0354</PDBx:U23>
         <PDBx:U33>0.4734</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="967">
         <PDBx:U11>0.7767</PDBx:U11>
         <PDBx:U12>0.0214</PDBx:U12>
         <PDBx:U13>0.0913</PDBx:U13>
         <PDBx:U22>0.3231</PDBx:U22>
         <PDBx:U23>0.0504</PDBx:U23>
         <PDBx:U33>0.4549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="968">
         <PDBx:U11>0.8676</PDBx:U11>
         <PDBx:U12>0.0614</PDBx:U12>
         <PDBx:U13>0.0986</PDBx:U13>
         <PDBx:U22>0.3961</PDBx:U22>
         <PDBx:U23>0.0799</PDBx:U23>
         <PDBx:U33>0.5304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="969">
         <PDBx:U11>0.8533</PDBx:U11>
         <PDBx:U12>0.0702</PDBx:U12>
         <PDBx:U13>0.0696</PDBx:U13>
         <PDBx:U22>0.4211</PDBx:U22>
         <PDBx:U23>0.0904</PDBx:U23>
         <PDBx:U33>0.5241</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="970">
         <PDBx:U11>0.8692</PDBx:U11>
         <PDBx:U12>0.1041</PDBx:U12>
         <PDBx:U13>0.0560</PDBx:U13>
         <PDBx:U22>0.4650</PDBx:U22>
         <PDBx:U23>0.1213</PDBx:U23>
         <PDBx:U33>0.5294</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="971">
         <PDBx:U11>0.9381</PDBx:U11>
         <PDBx:U12>0.0687</PDBx:U12>
         <PDBx:U13>0.1285</PDBx:U13>
         <PDBx:U22>0.4409</PDBx:U22>
         <PDBx:U23>0.0728</PDBx:U23>
         <PDBx:U33>0.6136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="972">
         <PDBx:U11>1.0425</PDBx:U11>
         <PDBx:U12>0.1108</PDBx:U12>
         <PDBx:U13>0.1383</PDBx:U13>
         <PDBx:U22>0.5325</PDBx:U22>
         <PDBx:U23>0.1008</PDBx:U23>
         <PDBx:U33>0.7082</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="973">
         <PDBx:U11>0.7936</PDBx:U11>
         <PDBx:U12>0.0390</PDBx:U12>
         <PDBx:U13>0.0569</PDBx:U13>
         <PDBx:U22>0.3805</PDBx:U22>
         <PDBx:U23>0.0637</PDBx:U23>
         <PDBx:U33>0.4888</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="974">
         <PDBx:U11>0.7434</PDBx:U11>
         <PDBx:U12>0.0405</PDBx:U12>
         <PDBx:U13>0.0267</PDBx:U13>
         <PDBx:U22>0.3666</PDBx:U22>
         <PDBx:U23>0.0700</PDBx:U23>
         <PDBx:U33>0.4414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="975">
         <PDBx:U11>0.7038</PDBx:U11>
         <PDBx:U12>0.0427</PDBx:U12>
         <PDBx:U13>-0.0087</PDBx:U13>
         <PDBx:U22>0.3834</PDBx:U22>
         <PDBx:U23>0.0867</PDBx:U23>
         <PDBx:U33>0.3865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="976">
         <PDBx:U11>0.6865</PDBx:U11>
         <PDBx:U12>0.0683</PDBx:U12>
         <PDBx:U13>-0.0318</PDBx:U13>
         <PDBx:U22>0.4334</PDBx:U22>
         <PDBx:U23>0.1058</PDBx:U23>
         <PDBx:U33>0.3788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="977">
         <PDBx:U11>0.7115</PDBx:U11>
         <PDBx:U12>-0.0033</PDBx:U12>
         <PDBx:U13>0.0172</PDBx:U13>
         <PDBx:U22>0.3509</PDBx:U22>
         <PDBx:U23>0.0321</PDBx:U23>
         <PDBx:U33>0.4417</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="978">
         <PDBx:U11>0.6586</PDBx:U11>
         <PDBx:U12>-0.0129</PDBx:U12>
         <PDBx:U13>-0.0186</PDBx:U13>
         <PDBx:U22>0.3587</PDBx:U22>
         <PDBx:U23>0.0284</PDBx:U23>
         <PDBx:U33>0.4061</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="979">
         <PDBx:U11>0.7563</PDBx:U11>
         <PDBx:U12>0.0275</PDBx:U12>
         <PDBx:U13>-0.0155</PDBx:U13>
         <PDBx:U22>0.4928</PDBx:U22>
         <PDBx:U23>0.0472</PDBx:U23>
         <PDBx:U33>0.5194</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="980">
         <PDBx:U11>0.7470</PDBx:U11>
         <PDBx:U12>0.0122</PDBx:U12>
         <PDBx:U13>-0.0445</PDBx:U13>
         <PDBx:U22>0.5640</PDBx:U22>
         <PDBx:U23>0.0330</PDBx:U23>
         <PDBx:U33>0.5471</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="981">
         <PDBx:U11>0.7924</PDBx:U11>
         <PDBx:U12>0.0417</PDBx:U12>
         <PDBx:U13>-0.0533</PDBx:U13>
         <PDBx:U22>0.6706</PDBx:U22>
         <PDBx:U23>0.0474</PDBx:U23>
         <PDBx:U33>0.6149</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="982">
         <PDBx:U11>0.8088</PDBx:U11>
         <PDBx:U12>0.0909</PDBx:U12>
         <PDBx:U13>-0.0376</PDBx:U13>
         <PDBx:U22>0.6790</PDBx:U22>
         <PDBx:U23>0.0777</PDBx:U23>
         <PDBx:U33>0.6221</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="983">
         <PDBx:U11>0.7558</PDBx:U11>
         <PDBx:U12>0.0223</PDBx:U12>
         <PDBx:U13>-0.0773</PDBx:U13>
         <PDBx:U22>0.7033</PDBx:U22>
         <PDBx:U23>0.0318</PDBx:U23>
         <PDBx:U33>0.6111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="984">
         <PDBx:U11>0.6814</PDBx:U11>
         <PDBx:U12>0.0138</PDBx:U12>
         <PDBx:U13>-0.0125</PDBx:U13>
         <PDBx:U22>0.3554</PDBx:U22>
         <PDBx:U23>0.0722</PDBx:U23>
         <PDBx:U33>0.3578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="985">
         <PDBx:U11>0.6686</PDBx:U11>
         <PDBx:U12>0.0111</PDBx:U12>
         <PDBx:U13>-0.0399</PDBx:U13>
         <PDBx:U22>0.4074</PDBx:U22>
         <PDBx:U23>0.0798</PDBx:U23>
         <PDBx:U33>0.3457</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="986">
         <PDBx:U11>0.6843</PDBx:U11>
         <PDBx:U12>0.0514</PDBx:U12>
         <PDBx:U13>-0.0364</PDBx:U13>
         <PDBx:U22>0.4444</PDBx:U22>
         <PDBx:U23>0.1156</PDBx:U23>
         <PDBx:U33>0.3482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="987">
         <PDBx:U11>0.6384</PDBx:U11>
         <PDBx:U12>0.0587</PDBx:U12>
         <PDBx:U13>-0.0619</PDBx:U13>
         <PDBx:U22>0.4811</PDBx:U22>
         <PDBx:U23>0.1284</PDBx:U23>
         <PDBx:U33>0.3213</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="988">
         <PDBx:U11>0.7137</PDBx:U11>
         <PDBx:U12>-0.0243</PDBx:U12>
         <PDBx:U13>-0.0368</PDBx:U13>
         <PDBx:U22>0.4261</PDBx:U22>
         <PDBx:U23>0.0568</PDBx:U23>
         <PDBx:U33>0.3846</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="989">
         <PDBx:U11>0.7364</PDBx:U11>
         <PDBx:U12>-0.0695</PDBx:U12>
         <PDBx:U13>-0.0545</PDBx:U13>
         <PDBx:U22>0.4616</PDBx:U22>
         <PDBx:U23>0.0226</PDBx:U23>
         <PDBx:U33>0.4383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="990">
         <PDBx:U11>0.7356</PDBx:U11>
         <PDBx:U12>-0.0733</PDBx:U12>
         <PDBx:U13>-0.0686</PDBx:U13>
         <PDBx:U22>0.5160</PDBx:U22>
         <PDBx:U23>0.0187</PDBx:U23>
         <PDBx:U33>0.4867</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="991">
         <PDBx:U11>0.7519</PDBx:U11>
         <PDBx:U12>-0.0830</PDBx:U12>
         <PDBx:U13>-0.0413</PDBx:U13>
         <PDBx:U22>0.5004</PDBx:U22>
         <PDBx:U23>0.0136</PDBx:U23>
         <PDBx:U33>0.4780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="992">
         <PDBx:U11>0.6748</PDBx:U11>
         <PDBx:U12>-0.0777</PDBx:U12>
         <PDBx:U13>-0.0556</PDBx:U13>
         <PDBx:U22>0.5190</PDBx:U22>
         <PDBx:U23>0.0145</PDBx:U23>
         <PDBx:U33>0.4995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="993">
         <PDBx:U11>0.6728</PDBx:U11>
         <PDBx:U12>-0.0852</PDBx:U12>
         <PDBx:U13>-0.0368</PDBx:U13>
         <PDBx:U22>0.4865</PDBx:U22>
         <PDBx:U23>0.0149</PDBx:U23>
         <PDBx:U33>0.4589</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="994">
         <PDBx:U11>0.6322</PDBx:U11>
         <PDBx:U12>-0.0855</PDBx:U12>
         <PDBx:U13>-0.0447</PDBx:U13>
         <PDBx:U22>0.4734</PDBx:U22>
         <PDBx:U23>0.0188</PDBx:U23>
         <PDBx:U33>0.4466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="995">
         <PDBx:U11>0.7067</PDBx:U11>
         <PDBx:U12>0.0714</PDBx:U12>
         <PDBx:U13>-0.0042</PDBx:U13>
         <PDBx:U22>0.3983</PDBx:U22>
         <PDBx:U23>0.1277</PDBx:U23>
         <PDBx:U33>0.3479</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="996">
         <PDBx:U11>0.7883</PDBx:U11>
         <PDBx:U12>0.1068</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.4870</PDBx:U22>
         <PDBx:U23>0.1596</PDBx:U23>
         <PDBx:U33>0.4135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="997">
         <PDBx:U11>0.7452</PDBx:U11>
         <PDBx:U12>0.1411</PDBx:U12>
         <PDBx:U13>-0.0137</PDBx:U13>
         <PDBx:U22>0.4908</PDBx:U22>
         <PDBx:U23>0.1787</PDBx:U23>
         <PDBx:U33>0.3904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="998">
         <PDBx:U11>0.7679</PDBx:U11>
         <PDBx:U12>0.1570</PDBx:U12>
         <PDBx:U13>-0.0360</PDBx:U13>
         <PDBx:U22>0.5685</PDBx:U22>
         <PDBx:U23>0.1972</PDBx:U23>
         <PDBx:U33>0.4165</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="999">
         <PDBx:U11>0.8701</PDBx:U11>
         <PDBx:U12>0.1178</PDBx:U12>
         <PDBx:U13>0.0391</PDBx:U13>
         <PDBx:U22>0.4866</PDBx:U22>
         <PDBx:U23>0.1623</PDBx:U23>
         <PDBx:U33>0.4720</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1000">
         <PDBx:U11>1.0267</PDBx:U11>
         <PDBx:U12>0.1461</PDBx:U12>
         <PDBx:U13>0.0422</PDBx:U13>
         <PDBx:U22>0.6398</PDBx:U22>
         <PDBx:U23>0.1925</PDBx:U23>
         <PDBx:U33>0.6011</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1001">
         <PDBx:U11>1.1868</PDBx:U11>
         <PDBx:U12>0.1532</PDBx:U12>
         <PDBx:U13>0.0827</PDBx:U13>
         <PDBx:U22>0.7209</PDBx:U22>
         <PDBx:U23>0.1918</PDBx:U23>
         <PDBx:U33>0.7387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1002">
         <PDBx:U11>1.2620</PDBx:U11>
         <PDBx:U12>0.1152</PDBx:U12>
         <PDBx:U13>0.0986</PDBx:U13>
         <PDBx:U22>0.7591</PDBx:U22>
         <PDBx:U23>0.1595</PDBx:U23>
         <PDBx:U33>0.8136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1003">
         <PDBx:U11>1.2411</PDBx:U11>
         <PDBx:U12>0.0966</PDBx:U12>
         <PDBx:U13>0.1183</PDBx:U13>
         <PDBx:U22>0.7122</PDBx:U22>
         <PDBx:U23>0.1308</PDBx:U23>
         <PDBx:U33>0.8142</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1004">
         <PDBx:U11>1.2483</PDBx:U11>
         <PDBx:U12>0.1117</PDBx:U12>
         <PDBx:U13>0.1275</PDBx:U13>
         <PDBx:U22>0.7170</PDBx:U22>
         <PDBx:U23>0.1317</PDBx:U23>
         <PDBx:U33>0.8399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1005">
         <PDBx:U11>1.1835</PDBx:U11>
         <PDBx:U12>0.0624</PDBx:U12>
         <PDBx:U13>0.1274</PDBx:U13>
         <PDBx:U22>0.6419</PDBx:U22>
         <PDBx:U23>0.1006</PDBx:U23>
         <PDBx:U33>0.7630</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1006">
         <PDBx:U11>0.7661</PDBx:U11>
         <PDBx:U12>0.1502</PDBx:U12>
         <PDBx:U13>0.0014</PDBx:U13>
         <PDBx:U22>0.4888</PDBx:U22>
         <PDBx:U23>0.1709</PDBx:U23>
         <PDBx:U33>0.4268</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1007">
         <PDBx:U11>0.8678</PDBx:U11>
         <PDBx:U12>0.1822</PDBx:U12>
         <PDBx:U13>-0.0079</PDBx:U13>
         <PDBx:U22>0.6377</PDBx:U22>
         <PDBx:U23>0.1841</PDBx:U23>
         <PDBx:U33>0.5547</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1008">
         <PDBx:U11>0.8390</PDBx:U11>
         <PDBx:U12>0.1685</PDBx:U12>
         <PDBx:U13>-0.0509</PDBx:U13>
         <PDBx:U22>0.7081</PDBx:U22>
         <PDBx:U23>0.1790</PDBx:U23>
         <PDBx:U33>0.5552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1009">
         <PDBx:U11>0.8221</PDBx:U11>
         <PDBx:U12>0.1916</PDBx:U12>
         <PDBx:U13>-0.0667</PDBx:U13>
         <PDBx:U22>0.7481</PDBx:U22>
         <PDBx:U23>0.1925</PDBx:U23>
         <PDBx:U33>0.5588</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1010">
         <PDBx:U11>0.9337</PDBx:U11>
         <PDBx:U12>0.1835</PDBx:U12>
         <PDBx:U13>0.0152</PDBx:U13>
         <PDBx:U22>0.6634</PDBx:U22>
         <PDBx:U23>0.1699</PDBx:U23>
         <PDBx:U33>0.6340</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1011">
         <PDBx:U11>0.9837</PDBx:U11>
         <PDBx:U12>0.2093</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.7763</PDBx:U22>
         <PDBx:U23>0.1769</PDBx:U23>
         <PDBx:U33>0.7186</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1012">
         <PDBx:U11>1.1524</PDBx:U11>
         <PDBx:U12>0.2199</PDBx:U12>
         <PDBx:U13>0.0399</PDBx:U13>
         <PDBx:U22>0.8843</PDBx:U22>
         <PDBx:U23>0.1649</PDBx:U23>
         <PDBx:U33>0.9014</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1013">
         <PDBx:U11>0.9308</PDBx:U11>
         <PDBx:U12>0.1575</PDBx:U12>
         <PDBx:U13>0.0385</PDBx:U13>
         <PDBx:U22>0.6243</PDBx:U22>
         <PDBx:U23>0.1237</PDBx:U23>
         <PDBx:U33>0.6738</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1014">
         <PDBx:U11>0.7485</PDBx:U11>
         <PDBx:U12>0.1262</PDBx:U12>
         <PDBx:U13>-0.0676</PDBx:U13>
         <PDBx:U22>0.6365</PDBx:U22>
         <PDBx:U23>0.1548</PDBx:U23>
         <PDBx:U33>0.4714</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1015">
         <PDBx:U11>0.6554</PDBx:U11>
         <PDBx:U12>0.0988</PDBx:U12>
         <PDBx:U13>-0.1034</PDBx:U13>
         <PDBx:U22>0.6288</PDBx:U22>
         <PDBx:U23>0.1401</PDBx:U23>
         <PDBx:U33>0.4157</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1016">
         <PDBx:U11>0.6733</PDBx:U11>
         <PDBx:U12>0.0846</PDBx:U12>
         <PDBx:U13>-0.1237</PDBx:U13>
         <PDBx:U22>0.6716</PDBx:U22>
         <PDBx:U23>0.1440</PDBx:U23>
         <PDBx:U33>0.4264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1017">
         <PDBx:U11>0.6764</PDBx:U11>
         <PDBx:U12>0.0709</PDBx:U12>
         <PDBx:U13>-0.1481</PDBx:U13>
         <PDBx:U22>0.7107</PDBx:U22>
         <PDBx:U23>0.1281</PDBx:U23>
         <PDBx:U33>0.4501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1018">
         <PDBx:U11>0.5520</PDBx:U11>
         <PDBx:U12>0.0551</PDBx:U12>
         <PDBx:U13>-0.1078</PDBx:U13>
         <PDBx:U22>0.5402</PDBx:U22>
         <PDBx:U23>0.1112</PDBx:U23>
         <PDBx:U33>0.3324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1019">
         <PDBx:U11>0.5720</PDBx:U11>
         <PDBx:U12>0.0622</PDBx:U12>
         <PDBx:U13>-0.0995</PDBx:U13>
         <PDBx:U22>0.5331</PDBx:U22>
         <PDBx:U23>0.0977</PDBx:U23>
         <PDBx:U33>0.3538</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1020">
         <PDBx:U11>0.6136</PDBx:U11>
         <PDBx:U12>0.0113</PDBx:U12>
         <PDBx:U13>-0.1058</PDBx:U13>
         <PDBx:U22>0.6080</PDBx:U22>
         <PDBx:U23>0.0501</PDBx:U23>
         <PDBx:U33>0.4391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1021">
         <PDBx:U11>0.5895</PDBx:U11>
         <PDBx:U12>0.0291</PDBx:U12>
         <PDBx:U13>-0.1158</PDBx:U13>
         <PDBx:U22>0.6501</PDBx:U22>
         <PDBx:U23>0.0269</PDBx:U23>
         <PDBx:U33>0.4592</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1022">
         <PDBx:U11>0.6884</PDBx:U11>
         <PDBx:U12>0.0923</PDBx:U12>
         <PDBx:U13>-0.1095</PDBx:U13>
         <PDBx:U22>0.6491</PDBx:U22>
         <PDBx:U23>0.1603</PDBx:U23>
         <PDBx:U33>0.4058</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1023">
         <PDBx:U11>0.7105</PDBx:U11>
         <PDBx:U12>0.0783</PDBx:U12>
         <PDBx:U13>-0.1271</PDBx:U13>
         <PDBx:U22>0.6866</PDBx:U22>
         <PDBx:U23>0.1648</PDBx:U23>
         <PDBx:U33>0.4109</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1024">
         <PDBx:U11>0.7105</PDBx:U11>
         <PDBx:U12>0.0784</PDBx:U12>
         <PDBx:U13>-0.1271</PDBx:U13>
         <PDBx:U22>0.6866</PDBx:U22>
         <PDBx:U23>0.1649</PDBx:U23>
         <PDBx:U33>0.4109</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1025">
         <PDBx:U11>0.6549</PDBx:U11>
         <PDBx:U12>0.0311</PDBx:U12>
         <PDBx:U13>-0.1387</PDBx:U13>
         <PDBx:U22>0.6398</PDBx:U22>
         <PDBx:U23>0.1294</PDBx:U23>
         <PDBx:U33>0.3736</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1026">
         <PDBx:U11>0.6389</PDBx:U11>
         <PDBx:U12>0.0406</PDBx:U12>
         <PDBx:U13>-0.1580</PDBx:U13>
         <PDBx:U22>0.6286</PDBx:U22>
         <PDBx:U23>0.1103</PDBx:U23>
         <PDBx:U33>0.3507</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1027">
         <PDBx:U11>0.7506</PDBx:U11>
         <PDBx:U12>0.1063</PDBx:U12>
         <PDBx:U13>-0.1463</PDBx:U13>
         <PDBx:U22>0.7649</PDBx:U22>
         <PDBx:U23>0.1768</PDBx:U23>
         <PDBx:U33>0.4576</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1028">
         <PDBx:U11>0.7511</PDBx:U11>
         <PDBx:U12>0.1066</PDBx:U12>
         <PDBx:U13>-0.1461</PDBx:U13>
         <PDBx:U22>0.7651</PDBx:U22>
         <PDBx:U23>0.1770</PDBx:U23>
         <PDBx:U33>0.4579</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1029">
         <PDBx:U11>0.8136</PDBx:U11>
         <PDBx:U12>0.1566</PDBx:U12>
         <PDBx:U13>-0.1276</PDBx:U13>
         <PDBx:U22>0.8119</PDBx:U22>
         <PDBx:U23>0.2081</PDBx:U23>
         <PDBx:U33>0.5084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1030">
         <PDBx:U11>0.8139</PDBx:U11>
         <PDBx:U12>0.1015</PDBx:U12>
         <PDBx:U13>-0.1608</PDBx:U13>
         <PDBx:U22>0.8301</PDBx:U22>
         <PDBx:U23>0.1853</PDBx:U23>
         <PDBx:U33>0.4901</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1031">
         <PDBx:U11>0.8159</PDBx:U11>
         <PDBx:U12>0.1845</PDBx:U12>
         <PDBx:U13>-0.1274</PDBx:U13>
         <PDBx:U22>0.8423</PDBx:U22>
         <PDBx:U23>0.2144</PDBx:U23>
         <PDBx:U33>0.5376</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1032">
         <PDBx:U11>0.8538</PDBx:U11>
         <PDBx:U12>0.0908</PDBx:U12>
         <PDBx:U13>-0.1493</PDBx:U13>
         <PDBx:U22>0.8357</PDBx:U22>
         <PDBx:U23>0.1940</PDBx:U23>
         <PDBx:U33>0.4958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1033">
         <PDBx:U11>0.8600</PDBx:U11>
         <PDBx:U12>0.1684</PDBx:U12>
         <PDBx:U13>-0.1092</PDBx:U13>
         <PDBx:U22>0.8077</PDBx:U22>
         <PDBx:U23>0.2268</PDBx:U23>
         <PDBx:U33>0.5146</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1034">
         <PDBx:U11>0.8322</PDBx:U11>
         <PDBx:U12>0.1092</PDBx:U12>
         <PDBx:U13>-0.1837</PDBx:U13>
         <PDBx:U22>0.8921</PDBx:U22>
         <PDBx:U23>0.1825</PDBx:U23>
         <PDBx:U33>0.5221</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1035">
         <PDBx:U11>0.5447</PDBx:U11>
         <PDBx:U12>0.0340</PDBx:U12>
         <PDBx:U13>-0.0999</PDBx:U13>
         <PDBx:U22>0.5890</PDBx:U22>
         <PDBx:U23>0.1179</PDBx:U23>
         <PDBx:U33>0.3015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1036">
         <PDBx:U11>0.4627</PDBx:U11>
         <PDBx:U12>0.0355</PDBx:U12>
         <PDBx:U13>-0.1021</PDBx:U13>
         <PDBx:U22>0.4942</PDBx:U22>
         <PDBx:U23>0.0688</PDBx:U23>
         <PDBx:U33>0.2200</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1037">
         <PDBx:U11>0.5116</PDBx:U11>
         <PDBx:U12>0.0340</PDBx:U12>
         <PDBx:U13>-0.1097</PDBx:U13>
         <PDBx:U22>0.5417</PDBx:U22>
         <PDBx:U23>0.0676</PDBx:U23>
         <PDBx:U33>0.2441</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1038">
         <PDBx:U11>0.5744</PDBx:U11>
         <PDBx:U12>0.0376</PDBx:U12>
         <PDBx:U13>-0.0950</PDBx:U13>
         <PDBx:U22>0.5965</PDBx:U22>
         <PDBx:U23>0.0902</PDBx:U23>
         <PDBx:U33>0.2819</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1039">
         <PDBx:U11>0.4054</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>-0.0924</PDBx:U13>
         <PDBx:U22>0.3831</PDBx:U22>
         <PDBx:U23>0.0553</PDBx:U23>
         <PDBx:U33>0.1697</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1040">
         <PDBx:U11>0.4729</PDBx:U11>
         <PDBx:U12>-0.0441</PDBx:U12>
         <PDBx:U13>-0.0947</PDBx:U13>
         <PDBx:U22>0.4436</PDBx:U22>
         <PDBx:U23>0.0281</PDBx:U23>
         <PDBx:U33>0.2765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1041">
         <PDBx:U11>0.4430</PDBx:U11>
         <PDBx:U12>-0.0514</PDBx:U12>
         <PDBx:U13>-0.1000</PDBx:U13>
         <PDBx:U22>0.4504</PDBx:U22>
         <PDBx:U23>0.0192</PDBx:U23>
         <PDBx:U33>0.2906</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1042">
         <PDBx:U11>0.4593</PDBx:U11>
         <PDBx:U12>-0.0723</PDBx:U12>
         <PDBx:U13>-0.0795</PDBx:U13>
         <PDBx:U22>0.3635</PDBx:U22>
         <PDBx:U23>0.0202</PDBx:U23>
         <PDBx:U33>0.2631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1043">
         <PDBx:U11>0.5143</PDBx:U11>
         <PDBx:U12>0.0172</PDBx:U12>
         <PDBx:U13>-0.1302</PDBx:U13>
         <PDBx:U22>0.5627</PDBx:U22>
         <PDBx:U23>0.0494</PDBx:U23>
         <PDBx:U33>0.2646</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1044">
         <PDBx:U11>0.5329</PDBx:U11>
         <PDBx:U12>0.0081</PDBx:U12>
         <PDBx:U13>-0.1367</PDBx:U13>
         <PDBx:U22>0.5881</PDBx:U22>
         <PDBx:U23>0.0489</PDBx:U23>
         <PDBx:U33>0.2673</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1045">
         <PDBx:U11>0.5109</PDBx:U11>
         <PDBx:U12>-0.0351</PDBx:U12>
         <PDBx:U13>-0.1227</PDBx:U13>
         <PDBx:U22>0.5553</PDBx:U22>
         <PDBx:U23>0.0343</PDBx:U23>
         <PDBx:U33>0.2739</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1046">
         <PDBx:U11>0.4785</PDBx:U11>
         <PDBx:U12>-0.0609</PDBx:U12>
         <PDBx:U13>-0.1130</PDBx:U13>
         <PDBx:U22>0.5126</PDBx:U22>
         <PDBx:U23>0.0241</PDBx:U23>
         <PDBx:U33>0.2812</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1079">
         <PDBx:U11>0.4642</PDBx:U11>
         <PDBx:U12>-0.1345</PDBx:U12>
         <PDBx:U13>-0.0469</PDBx:U13>
         <PDBx:U22>0.3425</PDBx:U22>
         <PDBx:U23>0.0289</PDBx:U23>
         <PDBx:U33>0.2655</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1080">
         <PDBx:U11>0.5009</PDBx:U11>
         <PDBx:U12>-0.1192</PDBx:U12>
         <PDBx:U13>-0.0371</PDBx:U13>
         <PDBx:U22>0.3718</PDBx:U22>
         <PDBx:U23>0.0241</PDBx:U23>
         <PDBx:U33>0.3077</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1081">
         <PDBx:U11>0.4579</PDBx:U11>
         <PDBx:U12>-0.1443</PDBx:U12>
         <PDBx:U13>-0.0405</PDBx:U13>
         <PDBx:U22>0.3343</PDBx:U22>
         <PDBx:U23>0.0272</PDBx:U23>
         <PDBx:U33>0.2468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1082">
         <PDBx:U11>0.5065</PDBx:U11>
         <PDBx:U12>-0.1169</PDBx:U12>
         <PDBx:U13>-0.0236</PDBx:U13>
         <PDBx:U22>0.3724</PDBx:U22>
         <PDBx:U23>0.0165</PDBx:U23>
         <PDBx:U33>0.3057</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1083">
         <PDBx:U11>0.4609</PDBx:U11>
         <PDBx:U12>-0.1367</PDBx:U12>
         <PDBx:U13>-0.0254</PDBx:U13>
         <PDBx:U22>0.3307</PDBx:U22>
         <PDBx:U23>0.0190</PDBx:U23>
         <PDBx:U33>0.2470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1084">
         <PDBx:U11>0.4665</PDBx:U11>
         <PDBx:U12>-0.1254</PDBx:U12>
         <PDBx:U13>-0.0177</PDBx:U13>
         <PDBx:U22>0.3316</PDBx:U22>
         <PDBx:U23>0.0138</PDBx:U23>
         <PDBx:U33>0.2560</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1085">
         <PDBx:U11>0.3679</PDBx:U11>
         <PDBx:U12>-0.1398</PDBx:U12>
         <PDBx:U13>-0.0521</PDBx:U13>
         <PDBx:U22>0.3394</PDBx:U22>
         <PDBx:U23>0.0242</PDBx:U23>
         <PDBx:U33>0.2199</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1086">
         <PDBx:U11>0.4090</PDBx:U11>
         <PDBx:U12>-0.1457</PDBx:U12>
         <PDBx:U13>-0.0405</PDBx:U13>
         <PDBx:U22>0.3846</PDBx:U22>
         <PDBx:U23>0.0237</PDBx:U23>
         <PDBx:U33>0.2589</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1087">
         <PDBx:U11>0.3439</PDBx:U11>
         <PDBx:U12>-0.1398</PDBx:U12>
         <PDBx:U13>-0.0388</PDBx:U13>
         <PDBx:U22>0.3382</PDBx:U22>
         <PDBx:U23>0.0223</PDBx:U23>
         <PDBx:U33>0.2111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1088">
         <PDBx:U11>0.3792</PDBx:U11>
         <PDBx:U12>-0.1375</PDBx:U12>
         <PDBx:U13>-0.0311</PDBx:U13>
         <PDBx:U22>0.3701</PDBx:U22>
         <PDBx:U23>0.0201</PDBx:U23>
         <PDBx:U33>0.2456</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1089">
         <PDBx:U11>0.4285</PDBx:U11>
         <PDBx:U12>-0.1582</PDBx:U12>
         <PDBx:U13>-0.0420</PDBx:U13>
         <PDBx:U22>0.4194</PDBx:U22>
         <PDBx:U23>0.0199</PDBx:U23>
         <PDBx:U33>0.2715</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1090">
         <PDBx:U11>0.4473</PDBx:U11>
         <PDBx:U12>-0.1657</PDBx:U12>
         <PDBx:U13>-0.0411</PDBx:U13>
         <PDBx:U22>0.4113</PDBx:U22>
         <PDBx:U23>0.0206</PDBx:U23>
         <PDBx:U33>0.2662</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1091">
         <PDBx:U11>0.4437</PDBx:U11>
         <PDBx:U12>-0.1574</PDBx:U12>
         <PDBx:U13>-0.0565</PDBx:U13>
         <PDBx:U22>0.4731</PDBx:U22>
         <PDBx:U23>0.0159</PDBx:U23>
         <PDBx:U33>0.2998</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1092">
         <PDBx:U11>0.3600</PDBx:U11>
         <PDBx:U12>-0.1362</PDBx:U12>
         <PDBx:U13>-0.0472</PDBx:U13>
         <PDBx:U22>0.3757</PDBx:U22>
         <PDBx:U23>0.0212</PDBx:U23>
         <PDBx:U33>0.2423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1093">
         <PDBx:U11>0.3314</PDBx:U11>
         <PDBx:U12>-0.1319</PDBx:U12>
         <PDBx:U13>-0.0450</PDBx:U13>
         <PDBx:U22>0.3597</PDBx:U22>
         <PDBx:U23>0.0201</PDBx:U23>
         <PDBx:U33>0.2259</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1094">
         <PDBx:U11>0.3125</PDBx:U11>
         <PDBx:U12>-0.1226</PDBx:U12>
         <PDBx:U13>-0.0404</PDBx:U13>
         <PDBx:U22>0.3182</PDBx:U22>
         <PDBx:U23>0.0232</PDBx:U23>
         <PDBx:U33>0.2063</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1095">
         <PDBx:U11>0.3212</PDBx:U11>
         <PDBx:U12>-0.1195</PDBx:U12>
         <PDBx:U13>-0.0357</PDBx:U13>
         <PDBx:U22>0.3241</PDBx:U22>
         <PDBx:U23>0.0223</PDBx:U23>
         <PDBx:U33>0.2161</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1096">
         <PDBx:U11>0.3632</PDBx:U11>
         <PDBx:U12>-0.1299</PDBx:U12>
         <PDBx:U13>-0.0548</PDBx:U13>
         <PDBx:U22>0.4230</PDBx:U22>
         <PDBx:U23>0.0170</PDBx:U23>
         <PDBx:U33>0.2719</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1097">
         <PDBx:U11>0.3872</PDBx:U11>
         <PDBx:U12>-0.1389</PDBx:U12>
         <PDBx:U13>-0.0614</PDBx:U13>
         <PDBx:U22>0.4872</PDBx:U22>
         <PDBx:U23>0.0116</PDBx:U23>
         <PDBx:U33>0.2979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1098">
         <PDBx:U11>0.3091</PDBx:U11>
         <PDBx:U12>-0.1179</PDBx:U12>
         <PDBx:U13>-0.0434</PDBx:U13>
         <PDBx:U22>0.3002</PDBx:U22>
         <PDBx:U23>0.0254</PDBx:U23>
         <PDBx:U33>0.2008</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1099">
         <PDBx:U11>0.3300</PDBx:U11>
         <PDBx:U12>-0.1096</PDBx:U12>
         <PDBx:U13>-0.0398</PDBx:U13>
         <PDBx:U22>0.3027</PDBx:U22>
         <PDBx:U23>0.0269</PDBx:U23>
         <PDBx:U33>0.2194</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1100">
         <PDBx:U11>0.3050</PDBx:U11>
         <PDBx:U12>-0.1079</PDBx:U12>
         <PDBx:U13>-0.0329</PDBx:U13>
         <PDBx:U22>0.2652</PDBx:U22>
         <PDBx:U23>0.0254</PDBx:U23>
         <PDBx:U33>0.1845</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1101">
         <PDBx:U11>0.3328</PDBx:U11>
         <PDBx:U12>-0.1020</PDBx:U12>
         <PDBx:U13>-0.0307</PDBx:U13>
         <PDBx:U22>0.2926</PDBx:U22>
         <PDBx:U23>0.0232</PDBx:U23>
         <PDBx:U33>0.2174</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1102">
         <PDBx:U11>0.3900</PDBx:U11>
         <PDBx:U12>-0.1060</PDBx:U12>
         <PDBx:U13>-0.0441</PDBx:U13>
         <PDBx:U22>0.3476</PDBx:U22>
         <PDBx:U23>0.0278</PDBx:U23>
         <PDBx:U33>0.2755</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1103">
         <PDBx:U11>0.3820</PDBx:U11>
         <PDBx:U12>-0.1023</PDBx:U12>
         <PDBx:U13>-0.0531</PDBx:U13>
         <PDBx:U22>0.3572</PDBx:U22>
         <PDBx:U23>0.0243</PDBx:U23>
         <PDBx:U33>0.2831</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1104">
         <PDBx:U11>0.3761</PDBx:U11>
         <PDBx:U12>-0.0969</PDBx:U12>
         <PDBx:U13>-0.0581</PDBx:U13>
         <PDBx:U22>0.3319</PDBx:U22>
         <PDBx:U23>0.0227</PDBx:U23>
         <PDBx:U33>0.2700</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1105">
         <PDBx:U11>0.3453</PDBx:U11>
         <PDBx:U12>-0.0987</PDBx:U12>
         <PDBx:U13>-0.0503</PDBx:U13>
         <PDBx:U22>0.3326</PDBx:U22>
         <PDBx:U23>0.0229</PDBx:U23>
         <PDBx:U33>0.2581</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1106">
         <PDBx:U11>0.3996</PDBx:U11>
         <PDBx:U12>-0.1134</PDBx:U12>
         <PDBx:U13>-0.0300</PDBx:U13>
         <PDBx:U22>0.3526</PDBx:U22>
         <PDBx:U23>0.0243</PDBx:U23>
         <PDBx:U33>0.2668</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1107">
         <PDBx:U11>0.3739</PDBx:U11>
         <PDBx:U12>-0.1122</PDBx:U12>
         <PDBx:U13>-0.0231</PDBx:U13>
         <PDBx:U22>0.3209</PDBx:U22>
         <PDBx:U23>0.0179</PDBx:U23>
         <PDBx:U33>0.2361</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1108">
         <PDBx:U11>0.3109</PDBx:U11>
         <PDBx:U12>-0.1110</PDBx:U12>
         <PDBx:U13>-0.0215</PDBx:U13>
         <PDBx:U22>0.2714</PDBx:U22>
         <PDBx:U23>0.0129</PDBx:U23>
         <PDBx:U33>0.1857</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1109">
         <PDBx:U11>0.3372</PDBx:U11>
         <PDBx:U12>-0.1056</PDBx:U12>
         <PDBx:U13>-0.0194</PDBx:U13>
         <PDBx:U22>0.2971</PDBx:U22>
         <PDBx:U23>0.0065</PDBx:U23>
         <PDBx:U33>0.2213</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1110">
         <PDBx:U11>0.4067</PDBx:U11>
         <PDBx:U12>-0.1189</PDBx:U12>
         <PDBx:U13>-0.0189</PDBx:U13>
         <PDBx:U22>0.3442</PDBx:U22>
         <PDBx:U23>0.0149</PDBx:U23>
         <PDBx:U33>0.2545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1111">
         <PDBx:U11>0.4351</PDBx:U11>
         <PDBx:U12>-0.1200</PDBx:U12>
         <PDBx:U13>-0.0090</PDBx:U13>
         <PDBx:U22>0.3653</PDBx:U22>
         <PDBx:U23>0.0054</PDBx:U23>
         <PDBx:U33>0.2772</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1112">
         <PDBx:U11>0.4423</PDBx:U11>
         <PDBx:U12>-0.1274</PDBx:U12>
         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.3568</PDBx:U22>
         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.2647</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1113">
         <PDBx:U11>0.4526</PDBx:U11>
         <PDBx:U12>-0.1357</PDBx:U12>
         <PDBx:U13>-0.0041</PDBx:U13>
         <PDBx:U22>0.3739</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.2712</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1114">
         <PDBx:U11>0.4472</PDBx:U11>
         <PDBx:U12>-0.1428</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.3508</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.2465</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1115">
         <PDBx:U11>0.3784</PDBx:U11>
         <PDBx:U12>-0.1166</PDBx:U12>
         <PDBx:U13>-0.0232</PDBx:U13>
         <PDBx:U22>0.3518</PDBx:U22>
         <PDBx:U23>0.0143</PDBx:U23>
         <PDBx:U33>0.2556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1116">
         <PDBx:U11>0.3780</PDBx:U11>
         <PDBx:U12>-0.1160</PDBx:U12>
         <PDBx:U13>-0.0224</PDBx:U13>
         <PDBx:U22>0.3620</PDBx:U22>
         <PDBx:U23>0.0091</PDBx:U23>
         <PDBx:U33>0.2655</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1117">
         <PDBx:U11>0.3786</PDBx:U11>
         <PDBx:U12>-0.1161</PDBx:U12>
         <PDBx:U13>-0.0224</PDBx:U13>
         <PDBx:U22>0.3626</PDBx:U22>
         <PDBx:U23>0.0091</PDBx:U23>
         <PDBx:U33>0.2660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1118">
         <PDBx:U11>0.3360</PDBx:U11>
         <PDBx:U12>-0.1086</PDBx:U12>
         <PDBx:U13>-0.0259</PDBx:U13>
         <PDBx:U22>0.3207</PDBx:U22>
         <PDBx:U23>0.0110</PDBx:U23>
         <PDBx:U33>0.2337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1119">
         <PDBx:U11>0.3253</PDBx:U11>
         <PDBx:U12>-0.1047</PDBx:U12>
         <PDBx:U13>-0.0265</PDBx:U13>
         <PDBx:U22>0.3106</PDBx:U22>
         <PDBx:U23>0.0064</PDBx:U23>
         <PDBx:U33>0.2325</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1120">
         <PDBx:U11>0.4090</PDBx:U11>
         <PDBx:U12>-0.1256</PDBx:U12>
         <PDBx:U13>-0.0228</PDBx:U13>
         <PDBx:U22>0.4087</PDBx:U22>
         <PDBx:U23>0.0084</PDBx:U23>
         <PDBx:U33>0.2951</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1121">
         <PDBx:U11>0.4069</PDBx:U11>
         <PDBx:U12>-0.1257</PDBx:U12>
         <PDBx:U13>-0.0229</PDBx:U13>
         <PDBx:U22>0.4068</PDBx:U22>
         <PDBx:U23>0.0085</PDBx:U23>
         <PDBx:U33>0.2931</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1122">
         <PDBx:U11>0.4195</PDBx:U11>
         <PDBx:U12>-0.1343</PDBx:U12>
         <PDBx:U13>-0.0189</PDBx:U13>
         <PDBx:U22>0.4187</PDBx:U22>
         <PDBx:U23>0.0056</PDBx:U23>
         <PDBx:U33>0.2950</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1123">
         <PDBx:U11>0.4066</PDBx:U11>
         <PDBx:U12>-0.1275</PDBx:U12>
         <PDBx:U13>-0.0277</PDBx:U13>
         <PDBx:U22>0.4169</PDBx:U22>
         <PDBx:U23>0.0136</PDBx:U23>
         <PDBx:U33>0.2961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1124">
         <PDBx:U11>0.2927</PDBx:U11>
         <PDBx:U12>-0.1073</PDBx:U12>
         <PDBx:U13>-0.0287</PDBx:U13>
         <PDBx:U22>0.2773</PDBx:U22>
         <PDBx:U23>0.0172</PDBx:U23>
         <PDBx:U33>0.1897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1125">
         <PDBx:U11>0.3564</PDBx:U11>
         <PDBx:U12>-0.1021</PDBx:U12>
         <PDBx:U13>-0.0309</PDBx:U13>
         <PDBx:U22>0.3407</PDBx:U22>
         <PDBx:U23>0.0192</PDBx:U23>
         <PDBx:U33>0.2597</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1126">
         <PDBx:U11>0.2929</PDBx:U11>
         <PDBx:U12>-0.0950</PDBx:U12>
         <PDBx:U13>-0.0306</PDBx:U13>
         <PDBx:U22>0.2662</PDBx:U22>
         <PDBx:U23>0.0167</PDBx:U23>
         <PDBx:U33>0.1988</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1127">
         <PDBx:U11>0.2986</PDBx:U11>
         <PDBx:U12>-0.0920</PDBx:U12>
         <PDBx:U13>-0.0325</PDBx:U13>
         <PDBx:U22>0.2718</PDBx:U22>
         <PDBx:U23>0.0154</PDBx:U23>
         <PDBx:U33>0.2111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1128">
         <PDBx:U11>0.3272</PDBx:U11>
         <PDBx:U12>-0.1024</PDBx:U12>
         <PDBx:U13>-0.0331</PDBx:U13>
         <PDBx:U22>0.3150</PDBx:U22>
         <PDBx:U23>0.0233</PDBx:U23>
         <PDBx:U33>0.2316</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1129">
         <PDBx:U11>0.3668</PDBx:U11>
         <PDBx:U12>-0.1096</PDBx:U12>
         <PDBx:U13>-0.0348</PDBx:U13>
         <PDBx:U22>0.3748</PDBx:U22>
         <PDBx:U23>0.0225</PDBx:U23>
         <PDBx:U33>0.2760</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1130">
         <PDBx:U11>0.3237</PDBx:U11>
         <PDBx:U12>-0.0974</PDBx:U12>
         <PDBx:U13>-0.0337</PDBx:U13>
         <PDBx:U22>0.3076</PDBx:U22>
         <PDBx:U23>0.0245</PDBx:U23>
         <PDBx:U33>0.2313</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1131">
         <PDBx:U11>0.3320</PDBx:U11>
         <PDBx:U12>-0.1093</PDBx:U12>
         <PDBx:U13>-0.0384</PDBx:U13>
         <PDBx:U22>0.3515</PDBx:U22>
         <PDBx:U23>0.0226</PDBx:U23>
         <PDBx:U33>0.2488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1132">
         <PDBx:U11>0.2855</PDBx:U11>
         <PDBx:U12>-0.0936</PDBx:U12>
         <PDBx:U13>-0.0286</PDBx:U13>
         <PDBx:U22>0.2505</PDBx:U22>
         <PDBx:U23>0.0150</PDBx:U23>
         <PDBx:U33>0.1866</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1133">
         <PDBx:U11>0.3008</PDBx:U11>
         <PDBx:U12>-0.0890</PDBx:U12>
         <PDBx:U13>-0.0274</PDBx:U13>
         <PDBx:U22>0.2600</PDBx:U22>
         <PDBx:U23>0.0092</PDBx:U23>
         <PDBx:U33>0.2074</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1134">
         <PDBx:U11>0.2793</PDBx:U11>
         <PDBx:U12>-0.0880</PDBx:U12>
         <PDBx:U13>-0.0274</PDBx:U13>
         <PDBx:U22>0.2424</PDBx:U22>
         <PDBx:U23>0.0015</PDBx:U23>
         <PDBx:U33>0.1987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1135">
         <PDBx:U11>0.3638</PDBx:U11>
         <PDBx:U12>-0.0844</PDBx:U12>
         <PDBx:U13>-0.0300</PDBx:U13>
         <PDBx:U22>0.3266</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.2946</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1136">
         <PDBx:U11>0.3567</PDBx:U11>
         <PDBx:U12>-0.0904</PDBx:U12>
         <PDBx:U13>-0.0232</PDBx:U13>
         <PDBx:U22>0.3077</PDBx:U22>
         <PDBx:U23>0.0056</PDBx:U23>
         <PDBx:U33>0.2559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1137">
         <PDBx:U11>0.3580</PDBx:U11>
         <PDBx:U12>-0.0898</PDBx:U12>
         <PDBx:U13>-0.0249</PDBx:U13>
         <PDBx:U22>0.3029</PDBx:U22>
         <PDBx:U23>0.0113</PDBx:U23>
         <PDBx:U33>0.2485</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1138">
         <PDBx:U11>0.3106</PDBx:U11>
         <PDBx:U12>-0.0885</PDBx:U12>
         <PDBx:U13>-0.0198</PDBx:U13>
         <PDBx:U22>0.2595</PDBx:U22>
         <PDBx:U23>-0.0045</PDBx:U23>
         <PDBx:U33>0.2205</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1139">
         <PDBx:U11>0.3577</PDBx:U11>
         <PDBx:U12>-0.0920</PDBx:U12>
         <PDBx:U13>-0.0209</PDBx:U13>
         <PDBx:U22>0.2904</PDBx:U22>
         <PDBx:U23>0.0076</PDBx:U23>
         <PDBx:U33>0.2372</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1140">
         <PDBx:U11>0.2829</PDBx:U11>
         <PDBx:U12>-0.0921</PDBx:U12>
         <PDBx:U13>-0.0250</PDBx:U13>
         <PDBx:U22>0.2500</PDBx:U22>
         <PDBx:U23>-0.0019</PDBx:U23>
         <PDBx:U33>0.2018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1141">
         <PDBx:U11>0.2867</PDBx:U11>
         <PDBx:U12>-0.0915</PDBx:U12>
         <PDBx:U13>-0.0251</PDBx:U13>
         <PDBx:U22>0.2583</PDBx:U22>
         <PDBx:U23>-0.0113</PDBx:U23>
         <PDBx:U33>0.2218</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1142">
         <PDBx:U11>0.2947</PDBx:U11>
         <PDBx:U12>-0.0884</PDBx:U12>
         <PDBx:U13>-0.0313</PDBx:U13>
         <PDBx:U22>0.2694</PDBx:U22>
         <PDBx:U23>-0.0099</PDBx:U23>
         <PDBx:U33>0.2401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1143">
         <PDBx:U11>0.3403</PDBx:U11>
         <PDBx:U12>-0.0845</PDBx:U12>
         <PDBx:U13>-0.0348</PDBx:U13>
         <PDBx:U22>0.3146</PDBx:U22>
         <PDBx:U23>-0.0160</PDBx:U23>
         <PDBx:U33>0.3033</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1144">
         <PDBx:U11>0.3434</PDBx:U11>
         <PDBx:U12>-0.0982</PDBx:U12>
         <PDBx:U13>-0.0207</PDBx:U13>
         <PDBx:U22>0.3195</PDBx:U22>
         <PDBx:U23>-0.0149</PDBx:U23>
         <PDBx:U33>0.2732</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1145">
         <PDBx:U11>0.3483</PDBx:U11>
         <PDBx:U12>-0.0984</PDBx:U12>
         <PDBx:U13>-0.0209</PDBx:U13>
         <PDBx:U22>0.3298</PDBx:U22>
         <PDBx:U23>-0.0257</PDBx:U23>
         <PDBx:U33>0.2967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1146">
         <PDBx:U11>0.3846</PDBx:U11>
         <PDBx:U12>-0.0949</PDBx:U12>
         <PDBx:U13>-0.0200</PDBx:U13>
         <PDBx:U22>0.3628</PDBx:U22>
         <PDBx:U23>-0.0357</PDBx:U23>
         <PDBx:U33>0.3528</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1147">
         <PDBx:U11>0.3414</PDBx:U11>
         <PDBx:U12>-0.1073</PDBx:U12>
         <PDBx:U13>-0.0149</PDBx:U13>
         <PDBx:U22>0.3282</PDBx:U22>
         <PDBx:U23>-0.0289</PDBx:U23>
         <PDBx:U33>0.2797</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1148">
         <PDBx:U11>0.3355</PDBx:U11>
         <PDBx:U12>-0.0914</PDBx:U12>
         <PDBx:U13>-0.0327</PDBx:U13>
         <PDBx:U22>0.3137</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.2712</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1149">
         <PDBx:U11>0.3320</PDBx:U11>
         <PDBx:U12>-0.0908</PDBx:U12>
         <PDBx:U13>-0.0376</PDBx:U13>
         <PDBx:U22>0.3126</PDBx:U22>
         <PDBx:U23>-0.0012</PDBx:U23>
         <PDBx:U33>0.2741</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1150">
         <PDBx:U11>0.3460</PDBx:U11>
         <PDBx:U12>-0.0873</PDBx:U12>
         <PDBx:U13>-0.0415</PDBx:U13>
         <PDBx:U22>0.3204</PDBx:U22>
         <PDBx:U23>0.0051</PDBx:U23>
         <PDBx:U33>0.2867</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1151">
         <PDBx:U11>0.3750</PDBx:U11>
         <PDBx:U12>-0.0859</PDBx:U12>
         <PDBx:U13>-0.0466</PDBx:U13>
         <PDBx:U22>0.3474</PDBx:U22>
         <PDBx:U23>0.0050</PDBx:U23>
         <PDBx:U33>0.3231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1152">
         <PDBx:U11>0.3143</PDBx:U11>
         <PDBx:U12>-0.0976</PDBx:U12>
         <PDBx:U13>-0.0364</PDBx:U13>
         <PDBx:U22>0.3034</PDBx:U22>
         <PDBx:U23>0.0023</PDBx:U23>
         <PDBx:U33>0.2479</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1153">
         <PDBx:U11>0.4018</PDBx:U11>
         <PDBx:U12>-0.1038</PDBx:U12>
         <PDBx:U13>-0.0327</PDBx:U13>
         <PDBx:U22>0.3990</PDBx:U22>
         <PDBx:U23>-0.0039</PDBx:U23>
         <PDBx:U33>0.3344</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1154">
         <PDBx:U11>0.4206</PDBx:U11>
         <PDBx:U12>-0.1121</PDBx:U12>
         <PDBx:U13>-0.0316</PDBx:U13>
         <PDBx:U22>0.4298</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.3445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1155">
         <PDBx:U11>0.4063</PDBx:U11>
         <PDBx:U12>-0.1027</PDBx:U12>
         <PDBx:U13>-0.0346</PDBx:U13>
         <PDBx:U22>0.4051</PDBx:U22>
         <PDBx:U23>-0.0142</PDBx:U23>
         <PDBx:U33>0.3556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1156">
         <PDBx:U11>0.3101</PDBx:U11>
         <PDBx:U12>-0.0866</PDBx:U12>
         <PDBx:U13>-0.0394</PDBx:U13>
         <PDBx:U22>0.2808</PDBx:U22>
         <PDBx:U23>0.0102</PDBx:U23>
         <PDBx:U33>0.2408</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1157">
         <PDBx:U11>0.3039</PDBx:U11>
         <PDBx:U12>-0.0853</PDBx:U12>
         <PDBx:U13>-0.0419</PDBx:U13>
         <PDBx:U22>0.2700</PDBx:U22>
         <PDBx:U23>0.0159</PDBx:U23>
         <PDBx:U33>0.2307</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1158">
         <PDBx:U11>0.3557</PDBx:U11>
         <PDBx:U12>-0.0816</PDBx:U12>
         <PDBx:U13>-0.0442</PDBx:U13>
         <PDBx:U22>0.3159</PDBx:U22>
         <PDBx:U23>0.0121</PDBx:U23>
         <PDBx:U33>0.2892</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1159">
         <PDBx:U11>0.4492</PDBx:U11>
         <PDBx:U12>-0.0815</PDBx:U12>
         <PDBx:U13>-0.0491</PDBx:U13>
         <PDBx:U22>0.4058</PDBx:U22>
         <PDBx:U23>0.0146</PDBx:U23>
         <PDBx:U33>0.3845</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1160">
         <PDBx:U11>0.3485</PDBx:U11>
         <PDBx:U12>-0.0873</PDBx:U12>
         <PDBx:U13>-0.0387</PDBx:U13>
         <PDBx:U22>0.3160</PDBx:U22>
         <PDBx:U23>0.0209</PDBx:U23>
         <PDBx:U33>0.2653</PDBx:U33>
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         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U22>0.5446</PDBx:U22>
         <PDBx:U23>0.0936</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.4192</PDBx:U11>
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         <PDBx:U13>-0.1093</PDBx:U13>
         <PDBx:U22>0.6265</PDBx:U22>
         <PDBx:U23>0.1256</PDBx:U23>
         <PDBx:U33>0.4200</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.1532</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.1787</PDBx:U23>
         <PDBx:U33>0.4756</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.1509</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.1795</PDBx:U23>
         <PDBx:U33>0.5897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1177">
         <PDBx:U11>0.5627</PDBx:U11>
         <PDBx:U12>-0.0464</PDBx:U12>
         <PDBx:U13>-0.0577</PDBx:U13>
         <PDBx:U22>0.6094</PDBx:U22>
         <PDBx:U23>0.2543</PDBx:U23>
         <PDBx:U33>0.5906</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1178">
         <PDBx:U11>0.5007</PDBx:U11>
         <PDBx:U12>-0.0823</PDBx:U12>
         <PDBx:U13>-0.0259</PDBx:U13>
         <PDBx:U22>0.5616</PDBx:U22>
         <PDBx:U23>0.1718</PDBx:U23>
         <PDBx:U33>0.5750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1179">
         <PDBx:U11>0.5069</PDBx:U11>
         <PDBx:U12>-0.0975</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.5758</PDBx:U22>
         <PDBx:U23>0.1756</PDBx:U23>
         <PDBx:U33>0.5248</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1180">
         <PDBx:U11>0.5700</PDBx:U11>
         <PDBx:U12>-0.0775</PDBx:U12>
         <PDBx:U13>-0.0206</PDBx:U13>
         <PDBx:U22>0.5859</PDBx:U22>
         <PDBx:U23>0.2050</PDBx:U23>
         <PDBx:U33>0.6815</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1181">
         <PDBx:U11>0.6984</PDBx:U11>
         <PDBx:U12>-0.0626</PDBx:U12>
         <PDBx:U13>-0.0580</PDBx:U13>
         <PDBx:U22>0.7889</PDBx:U22>
         <PDBx:U23>0.2306</PDBx:U23>
         <PDBx:U33>0.6346</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1182">
         <PDBx:U11>0.8034</PDBx:U11>
         <PDBx:U12>-0.0524</PDBx:U12>
         <PDBx:U13>-0.0593</PDBx:U13>
         <PDBx:U22>0.8801</PDBx:U22>
         <PDBx:U23>0.2727</PDBx:U23>
         <PDBx:U33>0.6853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1183">
         <PDBx:U11>0.8451</PDBx:U11>
         <PDBx:U12>-0.0367</PDBx:U12>
         <PDBx:U13>-0.0933</PDBx:U13>
         <PDBx:U22>0.9377</PDBx:U22>
         <PDBx:U23>0.2840</PDBx:U23>
         <PDBx:U33>0.7106</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1184">
         <PDBx:U11>0.9058</PDBx:U11>
         <PDBx:U12>-0.0218</PDBx:U12>
         <PDBx:U13>-0.1001</PDBx:U13>
         <PDBx:U22>0.9815</PDBx:U22>
         <PDBx:U23>0.3168</PDBx:U23>
         <PDBx:U33>0.7776</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1185">
         <PDBx:U11>0.8310</PDBx:U11>
         <PDBx:U12>-0.0583</PDBx:U12>
         <PDBx:U13>-0.0444</PDBx:U13>
         <PDBx:U22>0.9087</PDBx:U22>
         <PDBx:U23>0.2748</PDBx:U23>
         <PDBx:U33>0.6369</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1186">
         <PDBx:U11>0.8800</PDBx:U11>
         <PDBx:U12>-0.0706</PDBx:U12>
         <PDBx:U13>-0.0079</PDBx:U13>
         <PDBx:U22>0.9477</PDBx:U22>
         <PDBx:U23>0.2742</PDBx:U23>
         <PDBx:U33>0.7038</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1187">
         <PDBx:U11>0.9879</PDBx:U11>
         <PDBx:U12>-0.0690</PDBx:U12>
         <PDBx:U13>0.0167</PDBx:U13>
         <PDBx:U22>1.0380</PDBx:U22>
         <PDBx:U23>0.3179</PDBx:U23>
         <PDBx:U33>0.8189</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1188">
         <PDBx:U11>0.8783</PDBx:U11>
         <PDBx:U12>-0.0851</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.9572</PDBx:U22>
         <PDBx:U23>0.2334</PDBx:U23>
         <PDBx:U33>0.7159</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1189">
         <PDBx:U11>0.9995</PDBx:U11>
         <PDBx:U12>-0.0822</PDBx:U12>
         <PDBx:U13>0.0488</PDBx:U13>
         <PDBx:U22>1.0486</PDBx:U22>
         <PDBx:U23>0.3228</PDBx:U23>
         <PDBx:U33>0.8553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1190">
         <PDBx:U11>0.8990</PDBx:U11>
         <PDBx:U12>-0.0961</PDBx:U12>
         <PDBx:U13>0.0329</PDBx:U13>
         <PDBx:U22>0.9725</PDBx:U22>
         <PDBx:U23>0.2340</PDBx:U23>
         <PDBx:U33>0.7573</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1191">
         <PDBx:U11>0.9420</PDBx:U11>
         <PDBx:U12>-0.0950</PDBx:U12>
         <PDBx:U13>0.0566</PDBx:U13>
         <PDBx:U22>1.0033</PDBx:U22>
         <PDBx:U23>0.2797</PDBx:U23>
         <PDBx:U33>0.8118</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1192">
         <PDBx:U11>0.9549</PDBx:U11>
         <PDBx:U12>-0.1079</PDBx:U12>
         <PDBx:U13>0.0873</PDBx:U13>
         <PDBx:U22>1.0186</PDBx:U22>
         <PDBx:U23>0.2855</PDBx:U23>
         <PDBx:U33>0.8528</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1193">
         <PDBx:U11>0.8617</PDBx:U11>
         <PDBx:U12>-0.0415</PDBx:U12>
         <PDBx:U13>-0.1171</PDBx:U13>
         <PDBx:U22>0.9870</PDBx:U22>
         <PDBx:U23>0.2588</PDBx:U23>
         <PDBx:U33>0.7084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1194">
         <PDBx:U11>0.9263</PDBx:U11>
         <PDBx:U12>-0.0302</PDBx:U12>
         <PDBx:U13>-0.1527</PDBx:U13>
         <PDBx:U22>1.0803</PDBx:U22>
         <PDBx:U23>0.2655</PDBx:U23>
         <PDBx:U33>0.7787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1195">
         <PDBx:U11>0.9464</PDBx:U11>
         <PDBx:U12>-0.0090</PDBx:U12>
         <PDBx:U13>-0.1570</PDBx:U13>
         <PDBx:U22>1.0943</PDBx:U22>
         <PDBx:U23>0.2868</PDBx:U23>
         <PDBx:U33>0.8521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1196">
         <PDBx:U11>0.9679</PDBx:U11>
         <PDBx:U12>0.0060</PDBx:U12>
         <PDBx:U13>-0.1836</PDBx:U13>
         <PDBx:U22>1.1329</PDBx:U22>
         <PDBx:U23>0.3050</PDBx:U23>
         <PDBx:U33>0.8696</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1197">
         <PDBx:U11>0.8717</PDBx:U11>
         <PDBx:U12>-0.0419</PDBx:U12>
         <PDBx:U13>-0.1704</PDBx:U13>
         <PDBx:U22>1.0713</PDBx:U22>
         <PDBx:U23>0.2310</PDBx:U23>
         <PDBx:U33>0.7550</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1198">
         <PDBx:U11>0.8463</PDBx:U11>
         <PDBx:U12>-0.0519</PDBx:U12>
         <PDBx:U13>-0.1447</PDBx:U13>
         <PDBx:U22>1.0425</PDBx:U22>
         <PDBx:U23>0.2013</PDBx:U23>
         <PDBx:U33>0.7731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1199">
         <PDBx:U11>0.8840</PDBx:U11>
         <PDBx:U12>-0.0546</PDBx:U12>
         <PDBx:U13>-0.1847</PDBx:U13>
         <PDBx:U22>1.0832</PDBx:U22>
         <PDBx:U23>0.2109</PDBx:U23>
         <PDBx:U33>0.7092</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1200">
         <PDBx:U11>0.9191</PDBx:U11>
         <PDBx:U12>-0.0068</PDBx:U12>
         <PDBx:U13>-0.1343</PDBx:U13>
         <PDBx:U22>1.0393</PDBx:U22>
         <PDBx:U23>0.2840</PDBx:U23>
         <PDBx:U33>0.8732</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1201">
         <PDBx:U11>0.9232</PDBx:U11>
         <PDBx:U12>0.0159</PDBx:U12>
         <PDBx:U13>-0.1413</PDBx:U13>
         <PDBx:U22>1.0238</PDBx:U22>
         <PDBx:U23>0.3007</PDBx:U23>
         <PDBx:U33>0.9240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1202">
         <PDBx:U11>0.9650</PDBx:U11>
         <PDBx:U12>0.0273</PDBx:U12>
         <PDBx:U13>-0.1464</PDBx:U13>
         <PDBx:U22>1.0328</PDBx:U22>
         <PDBx:U23>0.3463</PDBx:U23>
         <PDBx:U33>0.9328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1203">
         <PDBx:U11>1.0170</PDBx:U11>
         <PDBx:U12>0.0238</PDBx:U12>
         <PDBx:U13>-0.1292</PDBx:U13>
         <PDBx:U22>1.0401</PDBx:U22>
         <PDBx:U23>0.3697</PDBx:U23>
         <PDBx:U33>0.9897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1204">
         <PDBx:U11>0.8576</PDBx:U11>
         <PDBx:U12>0.0132</PDBx:U12>
         <PDBx:U13>-0.1220</PDBx:U13>
         <PDBx:U22>0.9235</PDBx:U22>
         <PDBx:U23>0.2862</PDBx:U23>
         <PDBx:U33>0.9113</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1205">
         <PDBx:U11>0.7413</PDBx:U11>
         <PDBx:U12>0.0179</PDBx:U12>
         <PDBx:U13>-0.1251</PDBx:U13>
         <PDBx:U22>0.8354</PDBx:U22>
         <PDBx:U23>0.2446</PDBx:U23>
         <PDBx:U33>0.8425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1206">
         <PDBx:U11>0.6985</PDBx:U11>
         <PDBx:U12>0.0416</PDBx:U12>
         <PDBx:U13>-0.1474</PDBx:U13>
         <PDBx:U22>0.8355</PDBx:U22>
         <PDBx:U23>0.2363</PDBx:U23>
         <PDBx:U33>0.8233</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1207">
         <PDBx:U11>0.6585</PDBx:U11>
         <PDBx:U12>0.0007</PDBx:U12>
         <PDBx:U13>-0.1051</PDBx:U13>
         <PDBx:U22>0.7407</PDBx:U22>
         <PDBx:U23>0.2159</PDBx:U23>
         <PDBx:U33>0.7810</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1208">
         <PDBx:U11>0.6296</PDBx:U11>
         <PDBx:U12>0.0497</PDBx:U12>
         <PDBx:U13>-0.1476</PDBx:U13>
         <PDBx:U22>0.7996</PDBx:U22>
         <PDBx:U23>0.2015</PDBx:U23>
         <PDBx:U33>0.7961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1209">
         <PDBx:U11>0.6149</PDBx:U11>
         <PDBx:U12>0.0074</PDBx:U12>
         <PDBx:U13>-0.1076</PDBx:U13>
         <PDBx:U22>0.7225</PDBx:U22>
         <PDBx:U23>0.1782</PDBx:U23>
         <PDBx:U33>0.7765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1210">
         <PDBx:U11>0.6069</PDBx:U11>
         <PDBx:U12>0.0328</PDBx:U12>
         <PDBx:U13>-0.1278</PDBx:U13>
         <PDBx:U22>0.7596</PDBx:U22>
         <PDBx:U23>0.1716</PDBx:U23>
         <PDBx:U33>0.7892</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1211">
         <PDBx:U11>0.9807</PDBx:U11>
         <PDBx:U12>0.0399</PDBx:U12>
         <PDBx:U13>-0.1724</PDBx:U13>
         <PDBx:U22>1.0720</PDBx:U22>
         <PDBx:U23>0.3616</PDBx:U23>
         <PDBx:U33>0.9182</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>462</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1212">
         <PDBx:U11>1.0450</PDBx:U11>
         <PDBx:U12>0.0538</PDBx:U12>
         <PDBx:U13>-0.1815</PDBx:U13>
         <PDBx:U22>1.1077</PDBx:U22>
         <PDBx:U23>0.4045</PDBx:U23>
         <PDBx:U33>0.9480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>462</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1213">
         <PDBx:U11>1.0449</PDBx:U11>
         <PDBx:U12>0.0815</PDBx:U12>
         <PDBx:U13>-0.2012</PDBx:U13>
         <PDBx:U22>1.0997</PDBx:U22>
         <PDBx:U23>0.4158</PDBx:U23>
         <PDBx:U33>0.9945</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>462</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1214">
         <PDBx:U11>1.0929</PDBx:U11>
         <PDBx:U12>0.0977</PDBx:U12>
         <PDBx:U13>-0.2185</PDBx:U13>
         <PDBx:U22>1.1350</PDBx:U22>
         <PDBx:U23>0.4477</PDBx:U23>
         <PDBx:U33>1.0187</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>462</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1215">
         <PDBx:U11>1.0535</PDBx:U11>
         <PDBx:U12>0.0534</PDBx:U12>
         <PDBx:U13>-0.1998</PDBx:U13>
         <PDBx:U22>1.1356</PDBx:U22>
         <PDBx:U23>0.4096</PDBx:U23>
         <PDBx:U33>0.8888</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>462</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>162</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1216">
         <PDBx:U11>0.9877</PDBx:U11>
         <PDBx:U12>-0.0275</PDBx:U12>
         <PDBx:U13>-0.0889</PDBx:U13>
         <PDBx:U22>0.7799</PDBx:U22>
         <PDBx:U23>0.3309</PDBx:U23>
         <PDBx:U33>1.2403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1217">
         <PDBx:U11>0.9083</PDBx:U11>
         <PDBx:U12>-0.0498</PDBx:U12>
         <PDBx:U13>-0.0604</PDBx:U13>
         <PDBx:U22>0.7482</PDBx:U22>
         <PDBx:U23>0.3080</PDBx:U23>
         <PDBx:U33>1.1442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1218">
         <PDBx:U11>0.8586</PDBx:U11>
         <PDBx:U12>-0.0756</PDBx:U12>
         <PDBx:U13>-0.0474</PDBx:U13>
         <PDBx:U22>0.6702</PDBx:U22>
         <PDBx:U23>0.3035</PDBx:U23>
         <PDBx:U33>1.1369</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1219">
         <PDBx:U11>0.7615</PDBx:U11>
         <PDBx:U12>-0.0916</PDBx:U12>
         <PDBx:U13>-0.0268</PDBx:U13>
         <PDBx:U22>0.6046</PDBx:U22>
         <PDBx:U23>0.2767</PDBx:U23>
         <PDBx:U33>1.0360</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1220">
         <PDBx:U11>0.9386</PDBx:U11>
         <PDBx:U12>-0.0603</PDBx:U12>
         <PDBx:U13>-0.0402</PDBx:U13>
         <PDBx:U22>0.8158</PDBx:U22>
         <PDBx:U23>0.3404</PDBx:U23>
         <PDBx:U33>1.1165</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1221">
         <PDBx:U11>0.8118</PDBx:U11>
         <PDBx:U12>-0.0446</PDBx:U12>
         <PDBx:U13>0.0182</PDBx:U13>
         <PDBx:U22>0.4084</PDBx:U22>
         <PDBx:U23>0.0311</PDBx:U23>
         <PDBx:U33>0.8286</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1222">
         <PDBx:U11>0.8007</PDBx:U11>
         <PDBx:U12>-0.0672</PDBx:U12>
         <PDBx:U13>0.0088</PDBx:U13>
         <PDBx:U22>0.4100</PDBx:U22>
         <PDBx:U23>0.0179</PDBx:U23>
         <PDBx:U33>0.8414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1223">
         <PDBx:U11>0.7240</PDBx:U11>
         <PDBx:U12>-0.0757</PDBx:U12>
         <PDBx:U13>-0.0034</PDBx:U13>
         <PDBx:U22>0.3393</PDBx:U22>
         <PDBx:U23>-0.0119</PDBx:U23>
         <PDBx:U33>0.7594</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1224">
         <PDBx:U11>0.6743</PDBx:U11>
         <PDBx:U12>-0.0920</PDBx:U12>
         <PDBx:U13>-0.0051</PDBx:U13>
         <PDBx:U22>0.3141</PDBx:U22>
         <PDBx:U23>-0.0227</PDBx:U23>
         <PDBx:U33>0.7042</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1225">
         <PDBx:U11>0.9454</PDBx:U11>
         <PDBx:U12>-0.0734</PDBx:U12>
         <PDBx:U13>-0.0124</PDBx:U13>
         <PDBx:U22>0.5151</PDBx:U22>
         <PDBx:U23>0.0278</PDBx:U23>
         <PDBx:U33>0.9915</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1226">
         <PDBx:U11>1.1179</PDBx:U11>
         <PDBx:U12>-0.0778</PDBx:U12>
         <PDBx:U13>-0.0011</PDBx:U13>
         <PDBx:U22>0.6379</PDBx:U22>
         <PDBx:U23>0.0519</PDBx:U23>
         <PDBx:U33>1.0649</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1227">
         <PDBx:U11>1.0922</PDBx:U11>
         <PDBx:U12>-0.0596</PDBx:U12>
         <PDBx:U13>0.0276</PDBx:U13>
         <PDBx:U22>0.6526</PDBx:U22>
         <PDBx:U23>0.0666</PDBx:U23>
         <PDBx:U33>1.0721</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1228">
         <PDBx:U11>1.2224</PDBx:U11>
         <PDBx:U12>-0.0876</PDBx:U12>
         <PDBx:U13>-0.0178</PDBx:U13>
         <PDBx:U22>0.7277</PDBx:U22>
         <PDBx:U23>0.0639</PDBx:U23>
         <PDBx:U33>1.2023</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1229">
         <PDBx:U11>0.7352</PDBx:U11>
         <PDBx:U12>-0.0635</PDBx:U12>
         <PDBx:U13>-0.0103</PDBx:U13>
         <PDBx:U22>0.3221</PDBx:U22>
         <PDBx:U23>-0.0251</PDBx:U23>
         <PDBx:U33>0.7583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1230">
         <PDBx:U11>0.7897</PDBx:U11>
         <PDBx:U12>-0.0692</PDBx:U12>
         <PDBx:U13>-0.0114</PDBx:U13>
         <PDBx:U22>0.3795</PDBx:U22>
         <PDBx:U23>-0.0548</PDBx:U23>
         <PDBx:U33>0.7988</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1231">
         <PDBx:U11>0.6996</PDBx:U11>
         <PDBx:U12>-0.0742</PDBx:U12>
         <PDBx:U13>-0.0109</PDBx:U13>
         <PDBx:U22>0.3366</PDBx:U22>
         <PDBx:U23>-0.0591</PDBx:U23>
         <PDBx:U33>0.7014</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1232">
         <PDBx:U11>0.6402</PDBx:U11>
         <PDBx:U12>-0.0882</PDBx:U12>
         <PDBx:U13>-0.0152</PDBx:U13>
         <PDBx:U22>0.2983</PDBx:U22>
         <PDBx:U23>-0.0733</PDBx:U23>
         <PDBx:U33>0.6317</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1233">
         <PDBx:U11>0.8688</PDBx:U11>
         <PDBx:U12>-0.0502</PDBx:U12>
         <PDBx:U13>-0.0059</PDBx:U13>
         <PDBx:U22>0.4236</PDBx:U22>
         <PDBx:U23>-0.0678</PDBx:U23>
         <PDBx:U33>0.8629</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1234">
         <PDBx:U11>0.8387</PDBx:U11>
         <PDBx:U12>-0.0527</PDBx:U12>
         <PDBx:U13>-0.0024</PDBx:U13>
         <PDBx:U22>0.4096</PDBx:U22>
         <PDBx:U23>-0.0955</PDBx:U23>
         <PDBx:U33>0.8165</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1235">
         <PDBx:U11>0.8185</PDBx:U11>
         <PDBx:U12>-0.0673</PDBx:U12>
         <PDBx:U13>-0.0039</PDBx:U13>
         <PDBx:U22>0.3831</PDBx:U22>
         <PDBx:U23>-0.1181</PDBx:U23>
         <PDBx:U33>0.7858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1236">
         <PDBx:U11>0.8083</PDBx:U11>
         <PDBx:U12>-0.0431</PDBx:U12>
         <PDBx:U13>0.0027</PDBx:U13>
         <PDBx:U22>0.4020</PDBx:U22>
         <PDBx:U23>-0.1030</PDBx:U23>
         <PDBx:U33>0.7759</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1237">
         <PDBx:U11>0.8288</PDBx:U11>
         <PDBx:U12>-0.0656</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.4127</PDBx:U22>
         <PDBx:U23>-0.1370</PDBx:U23>
         <PDBx:U33>0.7782</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1238">
         <PDBx:U11>0.8206</PDBx:U11>
         <PDBx:U12>-0.0515</PDBx:U12>
         <PDBx:U13>0.0042</PDBx:U13>
         <PDBx:U22>0.4220</PDBx:U22>
         <PDBx:U23>-0.1281</PDBx:U23>
         <PDBx:U33>0.7703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1239">
         <PDBx:U11>0.5923</PDBx:U11>
         <PDBx:U12>-0.0624</PDBx:U12>
         <PDBx:U13>-0.0074</PDBx:U13>
         <PDBx:U22>0.2433</PDBx:U22>
         <PDBx:U23>-0.0449</PDBx:U23>
         <PDBx:U33>0.5908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1240">
         <PDBx:U11>0.6148</PDBx:U11>
         <PDBx:U12>-0.0662</PDBx:U12>
         <PDBx:U13>-0.0109</PDBx:U13>
         <PDBx:U22>0.3028</PDBx:U22>
         <PDBx:U23>-0.0458</PDBx:U23>
         <PDBx:U33>0.5943</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1241">
         <PDBx:U11>0.5656</PDBx:U11>
         <PDBx:U12>-0.0809</PDBx:U12>
         <PDBx:U13>-0.0167</PDBx:U13>
         <PDBx:U22>0.2820</PDBx:U22>
         <PDBx:U23>-0.0375</PDBx:U23>
         <PDBx:U33>0.5416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1242">
         <PDBx:U11>0.5148</PDBx:U11>
         <PDBx:U12>-0.0879</PDBx:U12>
         <PDBx:U13>-0.0223</PDBx:U13>
         <PDBx:U22>0.2571</PDBx:U22>
         <PDBx:U23>-0.0455</PDBx:U23>
         <PDBx:U33>0.4774</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1243">
         <PDBx:U11>0.6303</PDBx:U11>
         <PDBx:U12>-0.0521</PDBx:U12>
         <PDBx:U13>-0.0109</PDBx:U13>
         <PDBx:U22>0.3225</PDBx:U22>
         <PDBx:U23>-0.0305</PDBx:U23>
         <PDBx:U33>0.6039</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1244">
         <PDBx:U11>0.6883</PDBx:U11>
         <PDBx:U12>-0.0339</PDBx:U12>
         <PDBx:U13>-0.0041</PDBx:U13>
         <PDBx:U22>0.3555</PDBx:U22>
         <PDBx:U23>-0.0405</PDBx:U23>
         <PDBx:U33>0.6644</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1245">
         <PDBx:U11>0.6287</PDBx:U11>
         <PDBx:U12>-0.0582</PDBx:U12>
         <PDBx:U13>-0.0178</PDBx:U13>
         <PDBx:U22>0.3568</PDBx:U22>
         <PDBx:U23>-0.0301</PDBx:U23>
         <PDBx:U33>0.5850</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1246">
         <PDBx:U11>0.6773</PDBx:U11>
         <PDBx:U12>-0.0176</PDBx:U12>
         <PDBx:U13>-0.0061</PDBx:U13>
         <PDBx:U22>0.3600</PDBx:U22>
         <PDBx:U23>-0.0269</PDBx:U23>
         <PDBx:U33>0.6532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1247">
         <PDBx:U11>0.6010</PDBx:U11>
         <PDBx:U12>-0.0838</PDBx:U12>
         <PDBx:U13>-0.0147</PDBx:U13>
         <PDBx:U22>0.3117</PDBx:U22>
         <PDBx:U23>-0.0202</PDBx:U23>
         <PDBx:U33>0.5878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1248">
         <PDBx:U11>0.6185</PDBx:U11>
         <PDBx:U12>-0.0959</PDBx:U12>
         <PDBx:U13>-0.0194</PDBx:U13>
         <PDBx:U22>0.3547</PDBx:U22>
         <PDBx:U23>-0.0125</PDBx:U23>
         <PDBx:U33>0.6032</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1249">
         <PDBx:U11>0.5428</PDBx:U11>
         <PDBx:U12>-0.1115</PDBx:U12>
         <PDBx:U13>-0.0224</PDBx:U13>
         <PDBx:U22>0.2828</PDBx:U22>
         <PDBx:U23>-0.0291</PDBx:U23>
         <PDBx:U33>0.5321</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1250">
         <PDBx:U11>0.5258</PDBx:U11>
         <PDBx:U12>-0.1199</PDBx:U12>
         <PDBx:U13>-0.0292</PDBx:U13>
         <PDBx:U22>0.2939</PDBx:U22>
         <PDBx:U23>-0.0295</PDBx:U23>
         <PDBx:U33>0.5081</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1251">
         <PDBx:U11>0.6815</PDBx:U11>
         <PDBx:U12>-0.0952</PDBx:U12>
         <PDBx:U13>-0.0151</PDBx:U13>
         <PDBx:U22>0.4101</PDBx:U22>
         <PDBx:U23>0.0097</PDBx:U23>
         <PDBx:U33>0.6742</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1252">
         <PDBx:U11>0.7580</PDBx:U11>
         <PDBx:U12>-0.0825</PDBx:U12>
         <PDBx:U13>-0.0180</PDBx:U13>
         <PDBx:U22>0.4971</PDBx:U22>
         <PDBx:U23>0.0279</PDBx:U23>
         <PDBx:U33>0.7414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1253">
         <PDBx:U11>0.8671</PDBx:U11>
         <PDBx:U12>-0.0739</PDBx:U12>
         <PDBx:U13>-0.0138</PDBx:U13>
         <PDBx:U22>0.5907</PDBx:U22>
         <PDBx:U23>0.0484</PDBx:U23>
         <PDBx:U33>0.8532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1254">
         <PDBx:U11>0.7802</PDBx:U11>
         <PDBx:U12>-0.0777</PDBx:U12>
         <PDBx:U13>-0.0253</PDBx:U13>
         <PDBx:U22>0.5446</PDBx:U22>
         <PDBx:U23>0.0288</PDBx:U23>
         <PDBx:U33>0.7516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1255">
         <PDBx:U11>0.8578</PDBx:U11>
         <PDBx:U12>-0.0647</PDBx:U12>
         <PDBx:U13>-0.0210</PDBx:U13>
         <PDBx:U22>0.6010</PDBx:U22>
         <PDBx:U23>0.0604</PDBx:U23>
         <PDBx:U33>0.8350</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1256">
         <PDBx:U11>0.8288</PDBx:U11>
         <PDBx:U12>-0.0681</PDBx:U12>
         <PDBx:U13>-0.0272</PDBx:U13>
         <PDBx:U22>0.5950</PDBx:U22>
         <PDBx:U23>0.0476</PDBx:U23>
         <PDBx:U33>0.7982</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1257">
         <PDBx:U11>0.5431</PDBx:U11>
         <PDBx:U12>-0.1147</PDBx:U12>
         <PDBx:U13>-0.0191</PDBx:U13>
         <PDBx:U22>0.2540</PDBx:U22>
         <PDBx:U23>-0.0425</PDBx:U23>
         <PDBx:U33>0.5446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1258">
         <PDBx:U11>0.5760</PDBx:U11>
         <PDBx:U12>-0.1304</PDBx:U12>
         <PDBx:U13>-0.0251</PDBx:U13>
         <PDBx:U22>0.2890</PDBx:U22>
         <PDBx:U23>-0.0612</PDBx:U23>
         <PDBx:U33>0.5791</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1259">
         <PDBx:U11>0.5996</PDBx:U11>
         <PDBx:U12>-0.1301</PDBx:U12>
         <PDBx:U13>-0.0320</PDBx:U13>
         <PDBx:U22>0.3351</PDBx:U22>
         <PDBx:U23>-0.0771</PDBx:U23>
         <PDBx:U33>0.5805</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1260">
         <PDBx:U11>0.4703</PDBx:U11>
         <PDBx:U12>-0.1424</PDBx:U12>
         <PDBx:U13>-0.0397</PDBx:U13>
         <PDBx:U22>0.2281</PDBx:U22>
         <PDBx:U23>-0.0848</PDBx:U23>
         <PDBx:U33>0.4443</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1261">
         <PDBx:U11>0.6777</PDBx:U11>
         <PDBx:U12>-0.1330</PDBx:U12>
         <PDBx:U13>-0.0240</PDBx:U13>
         <PDBx:U22>0.3482</PDBx:U22>
         <PDBx:U23>-0.0726</PDBx:U23>
         <PDBx:U33>0.6936</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1262">
         <PDBx:U11>0.7293</PDBx:U11>
         <PDBx:U12>-0.1411</PDBx:U12>
         <PDBx:U13>-0.0202</PDBx:U13>
         <PDBx:U22>0.3784</PDBx:U22>
         <PDBx:U23>-0.0581</PDBx:U23>
         <PDBx:U33>0.7684</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1263">
         <PDBx:U11>0.8943</PDBx:U11>
         <PDBx:U12>-0.1484</PDBx:U12>
         <PDBx:U13>-0.0246</PDBx:U13>
         <PDBx:U22>0.4982</PDBx:U22>
         <PDBx:U23>-0.0714</PDBx:U23>
         <PDBx:U33>0.9351</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1264">
         <PDBx:U11>1.0092</PDBx:U11>
         <PDBx:U12>-0.1306</PDBx:U12>
         <PDBx:U13>-0.0229</PDBx:U13>
         <PDBx:U22>0.5758</PDBx:U22>
         <PDBx:U23>-0.0763</PDBx:U23>
         <PDBx:U33>1.0364</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1265">
         <PDBx:U11>1.0788</PDBx:U11>
         <PDBx:U12>-0.1177</PDBx:U12>
         <PDBx:U13>-0.0193</PDBx:U13>
         <PDBx:U22>0.6081</PDBx:U22>
         <PDBx:U23>-0.0588</PDBx:U23>
         <PDBx:U33>1.1071</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1266">
         <PDBx:U11>1.0966</PDBx:U11>
         <PDBx:U12>-0.1217</PDBx:U12>
         <PDBx:U13>-0.0186</PDBx:U13>
         <PDBx:U22>0.6226</PDBx:U22>
         <PDBx:U23>-0.0339</PDBx:U23>
         <PDBx:U33>1.1387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1267">
         <PDBx:U11>1.1163</PDBx:U11>
         <PDBx:U12>-0.0998</PDBx:U12>
         <PDBx:U13>-0.0152</PDBx:U13>
         <PDBx:U22>0.6108</PDBx:U22>
         <PDBx:U23>-0.0661</PDBx:U23>
         <PDBx:U33>1.1290</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1268">
         <PDBx:U11>0.5220</PDBx:U11>
         <PDBx:U12>-0.1162</PDBx:U12>
         <PDBx:U13>-0.0289</PDBx:U13>
         <PDBx:U22>0.2523</PDBx:U22>
         <PDBx:U23>-0.0809</PDBx:U23>
         <PDBx:U33>0.4914</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1269">
         <PDBx:U11>0.5402</PDBx:U11>
         <PDBx:U12>-0.1149</PDBx:U12>
         <PDBx:U13>-0.0327</PDBx:U13>
         <PDBx:U22>0.2906</PDBx:U22>
         <PDBx:U23>-0.0932</PDBx:U23>
         <PDBx:U33>0.4865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1270">
         <PDBx:U11>0.4899</PDBx:U11>
         <PDBx:U12>-0.1158</PDBx:U12>
         <PDBx:U13>-0.0379</PDBx:U13>
         <PDBx:U22>0.2755</PDBx:U22>
         <PDBx:U23>-0.0789</PDBx:U23>
         <PDBx:U33>0.4256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1271">
         <PDBx:U11>0.4660</PDBx:U11>
         <PDBx:U12>-0.1220</PDBx:U12>
         <PDBx:U13>-0.0444</PDBx:U13>
         <PDBx:U22>0.2732</PDBx:U22>
         <PDBx:U23>-0.0847</PDBx:U23>
         <PDBx:U33>0.3867</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1272">
         <PDBx:U11>0.5710</PDBx:U11>
         <PDBx:U12>-0.1001</PDBx:U12>
         <PDBx:U13>-0.0259</PDBx:U13>
         <PDBx:U22>0.3073</PDBx:U22>
         <PDBx:U23>-0.0999</PDBx:U23>
         <PDBx:U33>0.5084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1273">
         <PDBx:U11>0.6025</PDBx:U11>
         <PDBx:U12>-0.1000</PDBx:U12>
         <PDBx:U13>-0.0275</PDBx:U13>
         <PDBx:U22>0.3614</PDBx:U22>
         <PDBx:U23>-0.1099</PDBx:U23>
         <PDBx:U33>0.5144</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1274">
         <PDBx:U11>0.6165</PDBx:U11>
         <PDBx:U12>-0.0962</PDBx:U12>
         <PDBx:U13>-0.0211</PDBx:U13>
         <PDBx:U22>0.3134</PDBx:U22>
         <PDBx:U23>-0.1144</PDBx:U23>
         <PDBx:U33>0.5605</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1275">
         <PDBx:U11>0.4704</PDBx:U11>
         <PDBx:U12>-0.1090</PDBx:U12>
         <PDBx:U13>-0.0358</PDBx:U13>
         <PDBx:U22>0.2599</PDBx:U22>
         <PDBx:U23>-0.0597</PDBx:U23>
         <PDBx:U33>0.4123</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1276">
         <PDBx:U11>0.4704</PDBx:U11>
         <PDBx:U12>-0.1086</PDBx:U12>
         <PDBx:U13>-0.0409</PDBx:U13>
         <PDBx:U22>0.2875</PDBx:U22>
         <PDBx:U23>-0.0456</PDBx:U23>
         <PDBx:U33>0.4031</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1277">
         <PDBx:U11>0.4455</PDBx:U11>
         <PDBx:U12>-0.1216</PDBx:U12>
         <PDBx:U13>-0.0480</PDBx:U13>
         <PDBx:U22>0.2803</PDBx:U22>
         <PDBx:U23>-0.0438</PDBx:U23>
         <PDBx:U33>0.3818</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1278">
         <PDBx:U11>0.4119</PDBx:U11>
         <PDBx:U12>-0.1238</PDBx:U12>
         <PDBx:U13>-0.0545</PDBx:U13>
         <PDBx:U22>0.2696</PDBx:U22>
         <PDBx:U23>-0.0407</PDBx:U23>
         <PDBx:U33>0.3365</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1279">
         <PDBx:U11>0.4397</PDBx:U11>
         <PDBx:U12>-0.0999</PDBx:U12>
         <PDBx:U13>-0.0382</PDBx:U13>
         <PDBx:U22>0.2562</PDBx:U22>
         <PDBx:U23>-0.0274</PDBx:U23>
         <PDBx:U33>0.3783</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1280">
         <PDBx:U11>0.4147</PDBx:U11>
         <PDBx:U12>-0.0883</PDBx:U12>
         <PDBx:U13>-0.0349</PDBx:U13>
         <PDBx:U22>0.2279</PDBx:U22>
         <PDBx:U23>-0.0263</PDBx:U23>
         <PDBx:U33>0.3458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1281">
         <PDBx:U11>0.4204</PDBx:U11>
         <PDBx:U12>-0.0820</PDBx:U12>
         <PDBx:U13>-0.0342</PDBx:U13>
         <PDBx:U22>0.2315</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.3586</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1282">
         <PDBx:U11>0.3806</PDBx:U11>
         <PDBx:U12>-0.0874</PDBx:U12>
         <PDBx:U13>-0.0371</PDBx:U13>
         <PDBx:U22>0.2133</PDBx:U22>
         <PDBx:U23>-0.0275</PDBx:U23>
         <PDBx:U33>0.2943</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1283">
         <PDBx:U11>0.4433</PDBx:U11>
         <PDBx:U12>-0.1306</PDBx:U12>
         <PDBx:U13>-0.0464</PDBx:U13>
         <PDBx:U22>0.2669</PDBx:U22>
         <PDBx:U23>-0.0449</PDBx:U23>
         <PDBx:U33>0.3971</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1284">
         <PDBx:U11>0.4207</PDBx:U11>
         <PDBx:U12>-0.1458</PDBx:U12>
         <PDBx:U13>-0.0529</PDBx:U13>
         <PDBx:U22>0.2624</PDBx:U22>
         <PDBx:U23>-0.0459</PDBx:U23>
         <PDBx:U33>0.3818</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1285">
         <PDBx:U11>0.4315</PDBx:U11>
         <PDBx:U12>-0.1533</PDBx:U12>
         <PDBx:U13>-0.0611</PDBx:U13>
         <PDBx:U22>0.2875</PDBx:U22>
         <PDBx:U23>-0.0630</PDBx:U23>
         <PDBx:U33>0.3804</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1286">
         <PDBx:U11>0.4475</PDBx:U11>
         <PDBx:U12>-0.1595</PDBx:U12>
         <PDBx:U13>-0.0700</PDBx:U13>
         <PDBx:U22>0.3333</PDBx:U22>
         <PDBx:U23>-0.0600</PDBx:U23>
         <PDBx:U33>0.3916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1287">
         <PDBx:U11>0.4299</PDBx:U11>
         <PDBx:U12>-0.1564</PDBx:U12>
         <PDBx:U13>-0.0480</PDBx:U13>
         <PDBx:U22>0.2520</PDBx:U22>
         <PDBx:U23>-0.0471</PDBx:U23>
         <PDBx:U33>0.4131</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1288">
         <PDBx:U11>0.4750</PDBx:U11>
         <PDBx:U12>-0.1529</PDBx:U12>
         <PDBx:U13>-0.0416</PDBx:U13>
         <PDBx:U22>0.2941</PDBx:U22>
         <PDBx:U23>-0.0262</PDBx:U23>
         <PDBx:U33>0.4685</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1289">
         <PDBx:U11>0.4458</PDBx:U11>
         <PDBx:U12>-0.1455</PDBx:U12>
         <PDBx:U13>-0.0440</PDBx:U13>
         <PDBx:U22>0.2849</PDBx:U22>
         <PDBx:U23>-0.0125</PDBx:U23>
         <PDBx:U33>0.4306</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1290">
         <PDBx:U11>0.4632</PDBx:U11>
         <PDBx:U12>-0.1578</PDBx:U12>
         <PDBx:U13>-0.0341</PDBx:U13>
         <PDBx:U22>0.2587</PDBx:U22>
         <PDBx:U23>-0.0231</PDBx:U23>
         <PDBx:U33>0.4727</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1291">
         <PDBx:U11>0.4387</PDBx:U11>
         <PDBx:U12>-0.1522</PDBx:U12>
         <PDBx:U13>-0.0585</PDBx:U13>
         <PDBx:U22>0.2742</PDBx:U22>
         <PDBx:U23>-0.0807</PDBx:U23>
         <PDBx:U33>0.3820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1292">
         <PDBx:U11>0.5263</PDBx:U11>
         <PDBx:U12>-0.1588</PDBx:U12>
         <PDBx:U13>-0.0658</PDBx:U13>
         <PDBx:U22>0.3732</PDBx:U22>
         <PDBx:U23>-0.0987</PDBx:U23>
         <PDBx:U33>0.4530</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1293">
         <PDBx:U11>0.4718</PDBx:U11>
         <PDBx:U12>-0.1522</PDBx:U12>
         <PDBx:U13>-0.0710</PDBx:U13>
         <PDBx:U22>0.3466</PDBx:U22>
         <PDBx:U23>-0.0915</PDBx:U23>
         <PDBx:U33>0.3764</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1294">
         <PDBx:U11>0.4716</PDBx:U11>
         <PDBx:U12>-0.1598</PDBx:U12>
         <PDBx:U13>-0.0811</PDBx:U13>
         <PDBx:U22>0.3727</PDBx:U22>
         <PDBx:U23>-0.0957</PDBx:U23>
         <PDBx:U33>0.3661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1295">
         <PDBx:U11>0.5901</PDBx:U11>
         <PDBx:U12>-0.1547</PDBx:U12>
         <PDBx:U13>-0.0600</PDBx:U13>
         <PDBx:U22>0.4067</PDBx:U22>
         <PDBx:U23>-0.1175</PDBx:U23>
         <PDBx:U33>0.5100</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1296">
         <PDBx:U11>0.7071</PDBx:U11>
         <PDBx:U12>-0.1625</PDBx:U12>
         <PDBx:U13>-0.0667</PDBx:U13>
         <PDBx:U22>0.5323</PDBx:U22>
         <PDBx:U23>-0.1381</PDBx:U23>
         <PDBx:U33>0.6059</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1297">
         <PDBx:U11>0.8088</PDBx:U11>
         <PDBx:U12>-0.1819</PDBx:U12>
         <PDBx:U13>-0.0747</PDBx:U13>
         <PDBx:U22>0.6352</PDBx:U22>
         <PDBx:U23>-0.1501</PDBx:U23>
         <PDBx:U33>0.7176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1298">
         <PDBx:U11>0.8877</PDBx:U11>
         <PDBx:U12>-0.1908</PDBx:U12>
         <PDBx:U13>-0.0834</PDBx:U13>
         <PDBx:U22>0.7297</PDBx:U22>
         <PDBx:U23>-0.1696</PDBx:U23>
         <PDBx:U33>0.7716</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1299">
         <PDBx:U11>0.9083</PDBx:U11>
         <PDBx:U12>-0.1818</PDBx:U12>
         <PDBx:U13>-0.0755</PDBx:U13>
         <PDBx:U22>0.7264</PDBx:U22>
         <PDBx:U23>-0.1855</PDBx:U23>
         <PDBx:U33>0.7702</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1300">
         <PDBx:U11>0.4024</PDBx:U11>
         <PDBx:U12>-0.1384</PDBx:U12>
         <PDBx:U13>-0.0645</PDBx:U13>
         <PDBx:U22>0.2715</PDBx:U22>
         <PDBx:U23>-0.0798</PDBx:U23>
         <PDBx:U33>0.3001</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1301">
         <PDBx:U11>0.4214</PDBx:U11>
         <PDBx:U12>-0.1320</PDBx:U12>
         <PDBx:U13>-0.0675</PDBx:U13>
         <PDBx:U22>0.3097</PDBx:U22>
         <PDBx:U23>-0.0711</PDBx:U23>
         <PDBx:U33>0.2986</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1302">
         <PDBx:U11>0.4034</PDBx:U11>
         <PDBx:U12>-0.1354</PDBx:U12>
         <PDBx:U13>-0.0760</PDBx:U13>
         <PDBx:U22>0.3176</PDBx:U22>
         <PDBx:U23>-0.0547</PDBx:U23>
         <PDBx:U33>0.2854</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1303">
         <PDBx:U11>0.4585</PDBx:U11>
         <PDBx:U12>-0.1347</PDBx:U12>
         <PDBx:U13>-0.0835</PDBx:U13>
         <PDBx:U22>0.3955</PDBx:U22>
         <PDBx:U23>-0.0500</PDBx:U23>
         <PDBx:U33>0.3260</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1304">
         <PDBx:U11>0.4538</PDBx:U11>
         <PDBx:U12>-0.1185</PDBx:U12>
         <PDBx:U13>-0.0579</PDBx:U13>
         <PDBx:U22>0.3275</PDBx:U22>
         <PDBx:U23>-0.0639</PDBx:U23>
         <PDBx:U33>0.3250</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1305">
         <PDBx:U11>0.5202</PDBx:U11>
         <PDBx:U12>-0.1143</PDBx:U12>
         <PDBx:U13>-0.0498</PDBx:U13>
         <PDBx:U22>0.3734</PDBx:U22>
         <PDBx:U23>-0.0808</PDBx:U23>
         <PDBx:U33>0.3875</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1306">
         <PDBx:U11>0.4642</PDBx:U11>
         <PDBx:U12>-0.1138</PDBx:U12>
         <PDBx:U13>-0.0599</PDBx:U13>
         <PDBx:U22>0.3532</PDBx:U22>
         <PDBx:U23>-0.0535</PDBx:U23>
         <PDBx:U33>0.3152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1307">
         <PDBx:U11>0.5369</PDBx:U11>
         <PDBx:U12>-0.1024</PDBx:U12>
         <PDBx:U13>-0.0405</PDBx:U13>
         <PDBx:U22>0.3796</PDBx:U22>
         <PDBx:U23>-0.0755</PDBx:U23>
         <PDBx:U33>0.4025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1308">
         <PDBx:U11>0.4232</PDBx:U11>
         <PDBx:U12>-0.1382</PDBx:U12>
         <PDBx:U13>-0.0747</PDBx:U13>
         <PDBx:U22>0.3350</PDBx:U22>
         <PDBx:U23>-0.0451</PDBx:U23>
         <PDBx:U33>0.3256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1309">
         <PDBx:U11>0.4358</PDBx:U11>
         <PDBx:U12>-0.1425</PDBx:U12>
         <PDBx:U13>-0.0822</PDBx:U13>
         <PDBx:U22>0.3744</PDBx:U22>
         <PDBx:U23>-0.0310</PDBx:U23>
         <PDBx:U33>0.3472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1310">
         <PDBx:U11>0.4342</PDBx:U11>
         <PDBx:U12>-0.1548</PDBx:U12>
         <PDBx:U13>-0.0936</PDBx:U13>
         <PDBx:U22>0.4023</PDBx:U22>
         <PDBx:U23>-0.0393</PDBx:U23>
         <PDBx:U33>0.3494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1311">
         <PDBx:U11>0.4024</PDBx:U11>
         <PDBx:U12>-0.1535</PDBx:U12>
         <PDBx:U13>-0.1032</PDBx:U13>
         <PDBx:U22>0.4027</PDBx:U22>
         <PDBx:U23>-0.0310</PDBx:U23>
         <PDBx:U33>0.3136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1312">
         <PDBx:U11>0.4451</PDBx:U11>
         <PDBx:U12>-0.1448</PDBx:U12>
         <PDBx:U13>-0.0771</PDBx:U13>
         <PDBx:U22>0.3766</PDBx:U22>
         <PDBx:U23>-0.0208</PDBx:U23>
         <PDBx:U33>0.3776</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1313">
         <PDBx:U11>0.3938</PDBx:U11>
         <PDBx:U12>-0.1321</PDBx:U12>
         <PDBx:U13>-0.0688</PDBx:U13>
         <PDBx:U22>0.3059</PDBx:U22>
         <PDBx:U23>-0.0117</PDBx:U23>
         <PDBx:U33>0.3220</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1314">
         <PDBx:U11>0.3686</PDBx:U11>
         <PDBx:U12>-0.1509</PDBx:U12>
         <PDBx:U13>-0.0843</PDBx:U13>
         <PDBx:U22>0.3331</PDBx:U22>
         <PDBx:U23>-0.0081</PDBx:U23>
         <PDBx:U33>0.3138</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1315">
         <PDBx:U11>0.3949</PDBx:U11>
         <PDBx:U12>-0.1660</PDBx:U12>
         <PDBx:U13>-0.0931</PDBx:U13>
         <PDBx:U22>0.3531</PDBx:U22>
         <PDBx:U23>-0.0556</PDBx:U23>
         <PDBx:U33>0.3192</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1316">
         <PDBx:U11>0.4294</PDBx:U11>
         <PDBx:U12>-0.1796</PDBx:U12>
         <PDBx:U13>-0.1046</PDBx:U13>
         <PDBx:U22>0.4148</PDBx:U22>
         <PDBx:U23>-0.0673</PDBx:U23>
         <PDBx:U33>0.3569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1317">
         <PDBx:U11>0.4922</PDBx:U11>
         <PDBx:U12>-0.1739</PDBx:U12>
         <PDBx:U13>-0.1129</PDBx:U13>
         <PDBx:U22>0.4981</PDBx:U22>
         <PDBx:U23>-0.0710</PDBx:U23>
         <PDBx:U33>0.3941</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1318">
         <PDBx:U11>0.4691</PDBx:U11>
         <PDBx:U12>-0.1774</PDBx:U12>
         <PDBx:U13>-0.1255</PDBx:U13>
         <PDBx:U22>0.5141</PDBx:U22>
         <PDBx:U23>-0.0678</PDBx:U23>
         <PDBx:U33>0.3713</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1319">
         <PDBx:U11>0.4794</PDBx:U11>
         <PDBx:U12>-0.1921</PDBx:U12>
         <PDBx:U13>-0.1015</PDBx:U13>
         <PDBx:U22>0.4400</PDBx:U22>
         <PDBx:U23>-0.0878</PDBx:U23>
         <PDBx:U33>0.4152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1320">
         <PDBx:U11>0.4973</PDBx:U11>
         <PDBx:U12>-0.1993</PDBx:U12>
         <PDBx:U13>-0.0937</PDBx:U13>
         <PDBx:U22>0.4396</PDBx:U22>
         <PDBx:U23>-0.0824</PDBx:U23>
         <PDBx:U33>0.4598</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1321">
         <PDBx:U11>0.4663</PDBx:U11>
         <PDBx:U12>-0.1978</PDBx:U12>
         <PDBx:U13>-0.0926</PDBx:U13>
         <PDBx:U22>0.4242</PDBx:U22>
         <PDBx:U23>-0.0643</PDBx:U23>
         <PDBx:U33>0.4412</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1322">
         <PDBx:U11>0.5270</PDBx:U11>
         <PDBx:U12>-0.2063</PDBx:U12>
         <PDBx:U13>-0.0884</PDBx:U13>
         <PDBx:U22>0.4386</PDBx:U22>
         <PDBx:U23>-0.0956</PDBx:U23>
         <PDBx:U33>0.4978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1323">
         <PDBx:U11>0.5129</PDBx:U11>
         <PDBx:U12>-0.1640</PDBx:U12>
         <PDBx:U13>-0.1055</PDBx:U13>
         <PDBx:U22>0.4945</PDBx:U22>
         <PDBx:U23>-0.0765</PDBx:U23>
         <PDBx:U33>0.3934</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1324">
         <PDBx:U11>0.5185</PDBx:U11>
         <PDBx:U12>-0.1582</PDBx:U12>
         <PDBx:U13>-0.1106</PDBx:U13>
         <PDBx:U22>0.5148</PDBx:U22>
         <PDBx:U23>-0.0797</PDBx:U23>
         <PDBx:U33>0.3711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1325">
         <PDBx:U11>0.4994</PDBx:U11>
         <PDBx:U12>-0.1469</PDBx:U12>
         <PDBx:U13>-0.1160</PDBx:U13>
         <PDBx:U22>0.5217</PDBx:U22>
         <PDBx:U23>-0.0576</PDBx:U23>
         <PDBx:U33>0.3447</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1326">
         <PDBx:U11>0.5093</PDBx:U11>
         <PDBx:U12>-0.1443</PDBx:U12>
         <PDBx:U13>-0.1266</PDBx:U13>
         <PDBx:U22>0.5619</PDBx:U22>
         <PDBx:U23>-0.0543</PDBx:U23>
         <PDBx:U33>0.3412</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1327">
         <PDBx:U11>0.5000</PDBx:U11>
         <PDBx:U12>-0.1501</PDBx:U12>
         <PDBx:U13>-0.0986</PDBx:U13>
         <PDBx:U22>0.4648</PDBx:U22>
         <PDBx:U23>-0.0894</PDBx:U23>
         <PDBx:U33>0.3340</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1328">
         <PDBx:U11>0.4842</PDBx:U11>
         <PDBx:U12>-0.1578</PDBx:U12>
         <PDBx:U13>-0.0936</PDBx:U13>
         <PDBx:U22>0.4233</PDBx:U22>
         <PDBx:U23>-0.1095</PDBx:U23>
         <PDBx:U33>0.3264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1329">
         <PDBx:U11>0.5329</PDBx:U11>
         <PDBx:U12>-0.1453</PDBx:U12>
         <PDBx:U13>-0.1024</PDBx:U13>
         <PDBx:U22>0.5135</PDBx:U22>
         <PDBx:U23>-0.0922</PDBx:U23>
         <PDBx:U33>0.3359</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1330">
         <PDBx:U11>0.5061</PDBx:U11>
         <PDBx:U12>-0.1392</PDBx:U12>
         <PDBx:U13>-0.1090</PDBx:U13>
         <PDBx:U22>0.5153</PDBx:U22>
         <PDBx:U23>-0.0419</PDBx:U23>
         <PDBx:U33>0.3598</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1331">
         <PDBx:U11>0.4839</PDBx:U11>
         <PDBx:U12>-0.1274</PDBx:U12>
         <PDBx:U13>-0.1129</PDBx:U13>
         <PDBx:U22>0.5121</PDBx:U22>
         <PDBx:U23>-0.0205</PDBx:U23>
         <PDBx:U33>0.3335</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1332">
         <PDBx:U11>0.4903</PDBx:U11>
         <PDBx:U12>-0.1297</PDBx:U12>
         <PDBx:U13>-0.1263</PDBx:U13>
         <PDBx:U22>0.5624</PDBx:U22>
         <PDBx:U23>-0.0114</PDBx:U23>
         <PDBx:U33>0.3582</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1333">
         <PDBx:U11>0.5424</PDBx:U11>
         <PDBx:U12>-0.1183</PDBx:U12>
         <PDBx:U13>-0.1342</PDBx:U13>
         <PDBx:U22>0.6427</PDBx:U22>
         <PDBx:U23>0.0012</PDBx:U23>
         <PDBx:U33>0.4020</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1334">
         <PDBx:U11>0.4458</PDBx:U11>
         <PDBx:U12>-0.1212</PDBx:U12>
         <PDBx:U13>-0.1033</PDBx:U13>
         <PDBx:U22>0.4492</PDBx:U22>
         <PDBx:U23>-0.0086</PDBx:U23>
         <PDBx:U33>0.3022</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1335">
         <PDBx:U11>0.4760</PDBx:U11>
         <PDBx:U12>-0.1122</PDBx:U12>
         <PDBx:U13>-0.0918</PDBx:U13>
         <PDBx:U22>0.4488</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.3119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1336">
         <PDBx:U11>0.5280</PDBx:U11>
         <PDBx:U12>-0.1095</PDBx:U12>
         <PDBx:U13>-0.0833</PDBx:U13>
         <PDBx:U22>0.4770</PDBx:U22>
         <PDBx:U23>-0.0013</PDBx:U23>
         <PDBx:U33>0.3741</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1337">
         <PDBx:U11>0.4747</PDBx:U11>
         <PDBx:U12>-0.0999</PDBx:U12>
         <PDBx:U13>-0.0935</PDBx:U13>
         <PDBx:U22>0.4594</PDBx:U22>
         <PDBx:U23>0.0046</PDBx:U23>
         <PDBx:U33>0.2891</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1338">
         <PDBx:U11>0.4502</PDBx:U11>
         <PDBx:U12>-0.1429</PDBx:U12>
         <PDBx:U13>-0.1276</PDBx:U13>
         <PDBx:U22>0.5289</PDBx:U22>
         <PDBx:U23>-0.0164</PDBx:U23>
         <PDBx:U33>0.3444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1339">
         <PDBx:U11>0.3730</PDBx:U11>
         <PDBx:U12>-0.1474</PDBx:U12>
         <PDBx:U13>-0.1389</PDBx:U13>
         <PDBx:U22>0.4980</PDBx:U22>
         <PDBx:U23>-0.0096</PDBx:U23>
         <PDBx:U33>0.2905</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1340">
         <PDBx:U11>0.4329</PDBx:U11>
         <PDBx:U12>-0.1517</PDBx:U12>
         <PDBx:U13>-0.1519</PDBx:U13>
         <PDBx:U22>0.5882</PDBx:U22>
         <PDBx:U23>-0.0198</PDBx:U23>
         <PDBx:U33>0.3410</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1341">
         <PDBx:U11>0.4480</PDBx:U11>
         <PDBx:U12>-0.1446</PDBx:U12>
         <PDBx:U13>-0.1633</PDBx:U13>
         <PDBx:U22>0.6473</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.3632</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1342">
         <PDBx:U11>0.4906</PDBx:U11>
         <PDBx:U12>-0.1636</PDBx:U12>
         <PDBx:U13>-0.1352</PDBx:U13>
         <PDBx:U22>0.6136</PDBx:U22>
         <PDBx:U23>-0.0146</PDBx:U23>
         <PDBx:U33>0.4376</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1343">
         <PDBx:U11>0.4251</PDBx:U11>
         <PDBx:U12>-0.1585</PDBx:U12>
         <PDBx:U13>-0.1243</PDBx:U13>
         <PDBx:U22>0.5272</PDBx:U22>
         <PDBx:U23>-0.0009</PDBx:U23>
         <PDBx:U33>0.3823</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1344">
         <PDBx:U11>0.4590</PDBx:U11>
         <PDBx:U12>-0.1714</PDBx:U12>
         <PDBx:U13>-0.1469</PDBx:U13>
         <PDBx:U22>0.6348</PDBx:U22>
         <PDBx:U23>-0.0118</PDBx:U23>
         <PDBx:U33>0.4314</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1345">
         <PDBx:U11>0.3910</PDBx:U11>
         <PDBx:U12>-0.1445</PDBx:U12>
         <PDBx:U13>-0.1277</PDBx:U13>
         <PDBx:U22>0.5244</PDBx:U22>
         <PDBx:U23>0.0210</PDBx:U23>
         <PDBx:U33>0.3577</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1346">
         <PDBx:U11>0.4882</PDBx:U11>
         <PDBx:U12>-0.1621</PDBx:U12>
         <PDBx:U13>-0.1502</PDBx:U13>
         <PDBx:U22>0.6206</PDBx:U22>
         <PDBx:U23>-0.0414</PDBx:U23>
         <PDBx:U33>0.3807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1347">
         <PDBx:U11>0.5103</PDBx:U11>
         <PDBx:U12>-0.1684</PDBx:U12>
         <PDBx:U13>-0.1626</PDBx:U13>
         <PDBx:U22>0.6674</PDBx:U22>
         <PDBx:U23>-0.0540</PDBx:U23>
         <PDBx:U33>0.3887</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1348">
         <PDBx:U11>0.5476</PDBx:U11>
         <PDBx:U12>-0.1503</PDBx:U12>
         <PDBx:U13>-0.1690</PDBx:U13>
         <PDBx:U22>0.7247</PDBx:U22>
         <PDBx:U23>-0.0399</PDBx:U23>
         <PDBx:U33>0.4002</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1349">
         <PDBx:U11>0.5927</PDBx:U11>
         <PDBx:U12>-0.1491</PDBx:U12>
         <PDBx:U13>-0.1835</PDBx:U13>
         <PDBx:U22>0.8110</PDBx:U22>
         <PDBx:U23>-0.0359</PDBx:U23>
         <PDBx:U33>0.4432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1350">
         <PDBx:U11>0.5377</PDBx:U11>
         <PDBx:U12>-0.1801</PDBx:U12>
         <PDBx:U13>-0.1568</PDBx:U13>
         <PDBx:U22>0.6595</PDBx:U22>
         <PDBx:U23>-0.0799</PDBx:U23>
         <PDBx:U33>0.4007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1351">
         <PDBx:U11>0.6887</PDBx:U11>
         <PDBx:U12>-0.1864</PDBx:U12>
         <PDBx:U13>-0.1686</PDBx:U13>
         <PDBx:U22>0.8314</PDBx:U22>
         <PDBx:U23>-0.0942</PDBx:U23>
         <PDBx:U33>0.5297</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1352">
         <PDBx:U11>0.7128</PDBx:U11>
         <PDBx:U12>-0.1763</PDBx:U12>
         <PDBx:U13>-0.1673</PDBx:U13>
         <PDBx:U22>0.8486</PDBx:U22>
         <PDBx:U23>-0.0961</PDBx:U23>
         <PDBx:U33>0.5185</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1353">
         <PDBx:U11>0.6928</PDBx:U11>
         <PDBx:U12>-0.2032</PDBx:U12>
         <PDBx:U13>-0.1819</PDBx:U13>
         <PDBx:U22>0.8639</PDBx:U22>
         <PDBx:U23>-0.1073</PDBx:U23>
         <PDBx:U33>0.5406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1354">
         <PDBx:U11>0.7110</PDBx:U11>
         <PDBx:U12>-0.1859</PDBx:U12>
         <PDBx:U13>-0.1795</PDBx:U13>
         <PDBx:U22>0.8698</PDBx:U22>
         <PDBx:U23>-0.1096</PDBx:U23>
         <PDBx:U33>0.5006</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1355">
         <PDBx:U11>0.7353</PDBx:U11>
         <PDBx:U12>-0.2027</PDBx:U12>
         <PDBx:U13>-0.1891</PDBx:U13>
         <PDBx:U22>0.9161</PDBx:U22>
         <PDBx:U23>-0.1171</PDBx:U23>
         <PDBx:U33>0.5501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1356">
         <PDBx:U11>0.5329</PDBx:U11>
         <PDBx:U12>-0.1362</PDBx:U12>
         <PDBx:U13>-0.1578</PDBx:U13>
         <PDBx:U22>0.6803</PDBx:U22>
         <PDBx:U23>-0.0314</PDBx:U23>
         <PDBx:U33>0.3662</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1357">
         <PDBx:U11>0.5693</PDBx:U11>
         <PDBx:U12>-0.1175</PDBx:U12>
         <PDBx:U13>-0.1602</PDBx:U13>
         <PDBx:U22>0.7268</PDBx:U22>
         <PDBx:U23>-0.0150</PDBx:U23>
         <PDBx:U33>0.3770</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1358">
         <PDBx:U11>0.5376</PDBx:U11>
         <PDBx:U12>-0.1023</PDBx:U12>
         <PDBx:U13>-0.1684</PDBx:U13>
         <PDBx:U22>0.7306</PDBx:U22>
         <PDBx:U23>0.0104</PDBx:U23>
         <PDBx:U33>0.3620</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1359">
         <PDBx:U11>0.5056</PDBx:U11>
         <PDBx:U12>-0.0907</PDBx:U12>
         <PDBx:U13>-0.1785</PDBx:U13>
         <PDBx:U22>0.7263</PDBx:U22>
         <PDBx:U23>0.0221</PDBx:U23>
         <PDBx:U33>0.3175</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1360">
         <PDBx:U11>0.5465</PDBx:U11>
         <PDBx:U12>-0.1074</PDBx:U12>
         <PDBx:U13>-0.1439</PDBx:U13>
         <PDBx:U22>0.6625</PDBx:U22>
         <PDBx:U23>-0.0104</PDBx:U23>
         <PDBx:U33>0.3353</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1361">
         <PDBx:U11>0.5760</PDBx:U11>
         <PDBx:U12>-0.1154</PDBx:U12>
         <PDBx:U13>-0.1343</PDBx:U13>
         <PDBx:U22>0.6613</PDBx:U22>
         <PDBx:U23>-0.0319</PDBx:U23>
         <PDBx:U33>0.3439</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1362">
         <PDBx:U11>0.5626</PDBx:U11>
         <PDBx:U12>-0.1075</PDBx:U12>
         <PDBx:U13>-0.1173</PDBx:U13>
         <PDBx:U22>0.6111</PDBx:U22>
         <PDBx:U23>-0.0264</PDBx:U23>
         <PDBx:U33>0.3229</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1363">
         <PDBx:U11>0.6178</PDBx:U11>
         <PDBx:U12>-0.1135</PDBx:U12>
         <PDBx:U13>-0.1414</PDBx:U13>
         <PDBx:U22>0.7198</PDBx:U22>
         <PDBx:U23>-0.0372</PDBx:U23>
         <PDBx:U33>0.3545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1364">
         <PDBx:U11>0.5092</PDBx:U11>
         <PDBx:U12>-0.1012</PDBx:U12>
         <PDBx:U13>-0.1635</PDBx:U13>
         <PDBx:U22>0.7007</PDBx:U22>
         <PDBx:U23>0.0195</PDBx:U23>
         <PDBx:U33>0.3617</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1365">
         <PDBx:U11>0.4815</PDBx:U11>
         <PDBx:U12>-0.0840</PDBx:U12>
         <PDBx:U13>-0.1679</PDBx:U13>
         <PDBx:U22>0.7044</PDBx:U22>
         <PDBx:U23>0.0437</PDBx:U23>
         <PDBx:U33>0.3540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1366">
         <PDBx:U11>0.5424</PDBx:U11>
         <PDBx:U12>-0.0892</PDBx:U12>
         <PDBx:U13>-0.1840</PDBx:U13>
         <PDBx:U22>0.8203</PDBx:U22>
         <PDBx:U23>0.0436</PDBx:U23>
         <PDBx:U33>0.4368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1367">
         <PDBx:U11>0.6011</PDBx:U11>
         <PDBx:U12>-0.0709</PDBx:U12>
         <PDBx:U13>-0.1916</PDBx:U13>
         <PDBx:U22>0.9122</PDBx:U22>
         <PDBx:U23>0.0628</PDBx:U23>
         <PDBx:U33>0.5007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1368">
         <PDBx:U11>0.4944</PDBx:U11>
         <PDBx:U12>-0.0832</PDBx:U12>
         <PDBx:U13>-0.1576</PDBx:U13>
         <PDBx:U22>0.7030</PDBx:U22>
         <PDBx:U23>0.0513</PDBx:U23>
         <PDBx:U33>0.3910</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1369">
         <PDBx:U11>0.5238</PDBx:U11>
         <PDBx:U12>-0.0775</PDBx:U12>
         <PDBx:U13>-0.1426</PDBx:U13>
         <PDBx:U22>0.6811</PDBx:U22>
         <PDBx:U23>0.0532</PDBx:U23>
         <PDBx:U33>0.4002</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1370">
         <PDBx:U11>0.4430</PDBx:U11>
         <PDBx:U12>-0.0774</PDBx:U12>
         <PDBx:U13>-0.1325</PDBx:U13>
         <PDBx:U22>0.5848</PDBx:U22>
         <PDBx:U23>0.0622</PDBx:U23>
         <PDBx:U33>0.3435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1371">
         <PDBx:U11>0.4223</PDBx:U11>
         <PDBx:U12>-0.0723</PDBx:U12>
         <PDBx:U13>-0.1169</PDBx:U13>
         <PDBx:U22>0.5041</PDBx:U22>
         <PDBx:U23>0.0606</PDBx:U23>
         <PDBx:U33>0.2915</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1372">
         <PDBx:U11>0.5029</PDBx:U11>
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         <PDBx:U13>-0.1881</PDBx:U13>
         <PDBx:U22>0.7883</PDBx:U22>
         <PDBx:U23>0.0225</PDBx:U23>
         <PDBx:U33>0.4112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1373">
         <PDBx:U11>0.5191</PDBx:U11>
         <PDBx:U12>-0.1237</PDBx:U12>
         <PDBx:U13>-0.2032</PDBx:U13>
         <PDBx:U22>0.8566</PDBx:U22>
         <PDBx:U23>0.0187</PDBx:U23>
         <PDBx:U33>0.4483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.5509</PDBx:U11>
         <PDBx:U12>-0.1168</PDBx:U12>
         <PDBx:U13>-0.2169</PDBx:U13>
         <PDBx:U22>0.9126</PDBx:U22>
         <PDBx:U23>0.0202</PDBx:U23>
         <PDBx:U33>0.4539</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.5675</PDBx:U11>
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         <PDBx:U13>-0.2304</PDBx:U13>
         <PDBx:U22>0.9802</PDBx:U22>
         <PDBx:U23>0.0311</PDBx:U23>
         <PDBx:U33>0.4846</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1376">
         <PDBx:U11>0.5225</PDBx:U11>
         <PDBx:U12>-0.1530</PDBx:U12>
         <PDBx:U13>-0.2027</PDBx:U13>
         <PDBx:U22>0.8516</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.4657</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1377">
         <PDBx:U11>0.5762</PDBx:U11>
         <PDBx:U12>-0.1175</PDBx:U12>
         <PDBx:U13>-0.2129</PDBx:U13>
         <PDBx:U22>0.9031</PDBx:U22>
         <PDBx:U23>0.0098</PDBx:U23>
         <PDBx:U33>0.4412</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1378">
         <PDBx:U11>0.6442</PDBx:U11>
         <PDBx:U12>-0.1111</PDBx:U12>
         <PDBx:U13>-0.2244</PDBx:U13>
         <PDBx:U22>0.9899</PDBx:U22>
         <PDBx:U23>0.0119</PDBx:U23>
         <PDBx:U33>0.4781</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1379">
         <PDBx:U11>0.6725</PDBx:U11>
         <PDBx:U12>-0.0814</PDBx:U12>
         <PDBx:U13>-0.2256</PDBx:U13>
         <PDBx:U22>1.0299</PDBx:U22>
         <PDBx:U23>0.0433</PDBx:U23>
         <PDBx:U33>0.4980</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1380">
         <PDBx:U11>0.7318</PDBx:U11>
         <PDBx:U12>-0.0729</PDBx:U12>
         <PDBx:U13>-0.2394</PDBx:U13>
         <PDBx:U22>1.1252</PDBx:U22>
         <PDBx:U23>0.0540</PDBx:U23>
         <PDBx:U33>0.5471</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1381">
         <PDBx:U11>0.6861</PDBx:U11>
         <PDBx:U12>-0.1187</PDBx:U12>
         <PDBx:U13>-0.2168</PDBx:U13>
         <PDBx:U22>0.9904</PDBx:U22>
         <PDBx:U23>-0.0069</PDBx:U23>
         <PDBx:U33>0.4814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1382">
         <PDBx:U11>0.7273</PDBx:U11>
         <PDBx:U12>-0.1458</PDBx:U12>
         <PDBx:U13>-0.2162</PDBx:U13>
         <PDBx:U22>1.0182</PDBx:U22>
         <PDBx:U23>-0.0386</PDBx:U23>
         <PDBx:U33>0.5265</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1383">
         <PDBx:U11>0.7487</PDBx:U11>
         <PDBx:U12>-0.1517</PDBx:U12>
         <PDBx:U13>-0.2173</PDBx:U13>
         <PDBx:U22>1.0267</PDBx:U22>
         <PDBx:U23>-0.0561</PDBx:U23>
         <PDBx:U33>0.5077</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1384">
         <PDBx:U11>0.7274</PDBx:U11>
         <PDBx:U12>-0.1338</PDBx:U12>
         <PDBx:U13>-0.2036</PDBx:U13>
         <PDBx:U22>0.9705</PDBx:U22>
         <PDBx:U23>-0.0457</PDBx:U23>
         <PDBx:U33>0.4556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.7702</PDBx:U11>
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         <PDBx:U13>-0.2040</PDBx:U13>
         <PDBx:U22>1.0060</PDBx:U22>
         <PDBx:U23>-0.0607</PDBx:U23>
         <PDBx:U33>0.4574</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1386">
         <PDBx:U11>0.6794</PDBx:U11>
         <PDBx:U12>-0.0656</PDBx:U12>
         <PDBx:U13>-0.2108</PDBx:U13>
         <PDBx:U22>1.0041</PDBx:U22>
         <PDBx:U23>0.0582</PDBx:U23>
         <PDBx:U33>0.5084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1387">
         <PDBx:U11>0.6927</PDBx:U11>
         <PDBx:U12>-0.0364</PDBx:U12>
         <PDBx:U13>-0.2082</PDBx:U13>
         <PDBx:U22>1.0167</PDBx:U22>
         <PDBx:U23>0.0881</PDBx:U23>
         <PDBx:U33>0.5142</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1388">
         <PDBx:U11>0.6504</PDBx:U11>
         <PDBx:U12>-0.0235</PDBx:U12>
         <PDBx:U13>-0.2185</PDBx:U13>
         <PDBx:U22>1.0266</PDBx:U22>
         <PDBx:U23>0.1064</PDBx:U23>
         <PDBx:U33>0.5080</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1389">
         <PDBx:U11>0.6828</PDBx:U11>
         <PDBx:U12>0.0022</PDBx:U12>
         <PDBx:U13>-0.2187</PDBx:U13>
         <PDBx:U22>1.0664</PDBx:U22>
         <PDBx:U23>0.1321</PDBx:U23>
         <PDBx:U33>0.5384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1390">
         <PDBx:U11>0.6906</PDBx:U11>
         <PDBx:U12>-0.0250</PDBx:U12>
         <PDBx:U13>-0.1885</PDBx:U13>
         <PDBx:U22>0.9636</PDBx:U22>
         <PDBx:U23>0.0967</PDBx:U23>
         <PDBx:U33>0.5077</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1391">
         <PDBx:U11>0.5871</PDBx:U11>
         <PDBx:U12>-0.0414</PDBx:U12>
         <PDBx:U13>-0.2254</PDBx:U13>
         <PDBx:U22>0.9979</PDBx:U22>
         <PDBx:U23>0.0932</PDBx:U23>
         <PDBx:U33>0.4786</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1392">
         <PDBx:U11>0.6004</PDBx:U11>
         <PDBx:U12>-0.0323</PDBx:U12>
         <PDBx:U13>-0.2353</PDBx:U13>
         <PDBx:U22>1.0693</PDBx:U22>
         <PDBx:U23>0.1073</PDBx:U23>
         <PDBx:U33>0.5298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1393">
         <PDBx:U11>0.5791</PDBx:U11>
         <PDBx:U12>-0.0223</PDBx:U12>
         <PDBx:U13>-0.2230</PDBx:U13>
         <PDBx:U22>1.0487</PDBx:U22>
         <PDBx:U23>0.1184</PDBx:U23>
         <PDBx:U33>0.5459</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1394">
         <PDBx:U11>0.5024</PDBx:U11>
         <PDBx:U12>-0.0084</PDBx:U12>
         <PDBx:U13>-0.2271</PDBx:U13>
         <PDBx:U22>1.0177</PDBx:U22>
         <PDBx:U23>0.1336</PDBx:U23>
         <PDBx:U33>0.5024</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1395">
         <PDBx:U11>0.5854</PDBx:U11>
         <PDBx:U12>-0.0289</PDBx:U12>
         <PDBx:U13>-0.2077</PDBx:U13>
         <PDBx:U22>1.0065</PDBx:U22>
         <PDBx:U23>0.1106</PDBx:U23>
         <PDBx:U33>0.5472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1396">
         <PDBx:U11>0.5478</PDBx:U11>
         <PDBx:U12>-0.0201</PDBx:U12>
         <PDBx:U13>-0.1947</PDBx:U13>
         <PDBx:U22>0.9655</PDBx:U22>
         <PDBx:U23>0.1205</PDBx:U23>
         <PDBx:U33>0.5402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1397">
         <PDBx:U11>0.4761</PDBx:U11>
         <PDBx:U12>-0.0398</PDBx:U12>
         <PDBx:U13>-0.1981</PDBx:U13>
         <PDBx:U22>0.9344</PDBx:U22>
         <PDBx:U23>0.1104</PDBx:U23>
         <PDBx:U33>0.5093</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1398">
         <PDBx:U11>0.4621</PDBx:U11>
         <PDBx:U12>-0.0683</PDBx:U12>
         <PDBx:U13>-0.2048</PDBx:U13>
         <PDBx:U22>0.9245</PDBx:U22>
         <PDBx:U23>0.0885</PDBx:U23>
         <PDBx:U33>0.4948</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1399">
         <PDBx:U11>0.5409</PDBx:U11>
         <PDBx:U12>-0.0240</PDBx:U12>
         <PDBx:U13>-0.1787</PDBx:U13>
         <PDBx:U22>0.8970</PDBx:U22>
         <PDBx:U23>0.1147</PDBx:U23>
         <PDBx:U33>0.5138</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1400">
         <PDBx:U11>0.5435</PDBx:U11>
         <PDBx:U12>-0.0012</PDBx:U12>
         <PDBx:U13>-0.1679</PDBx:U13>
         <PDBx:U22>0.8532</PDBx:U22>
         <PDBx:U23>0.1291</PDBx:U23>
         <PDBx:U33>0.4845</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1401">
         <PDBx:U11>0.5809</PDBx:U11>
         <PDBx:U12>-0.0010</PDBx:U12>
         <PDBx:U13>-0.1759</PDBx:U13>
         <PDBx:U22>0.8820</PDBx:U22>
         <PDBx:U23>0.1264</PDBx:U23>
         <PDBx:U33>0.4846</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1402">
         <PDBx:U11>0.5596</PDBx:U11>
         <PDBx:U12>-0.0092</PDBx:U12>
         <PDBx:U13>-0.1528</PDBx:U13>
         <PDBx:U22>0.8164</PDBx:U22>
         <PDBx:U23>0.1214</PDBx:U23>
         <PDBx:U33>0.4884</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1403">
         <PDBx:U11>0.4281</PDBx:U11>
         <PDBx:U12>-0.0243</PDBx:U12>
         <PDBx:U13>-0.1914</PDBx:U13>
         <PDBx:U22>0.9143</PDBx:U22>
         <PDBx:U23>0.1260</PDBx:U23>
         <PDBx:U33>0.4971</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1404">
         <PDBx:U11>0.4277</PDBx:U11>
         <PDBx:U12>-0.0239</PDBx:U12>
         <PDBx:U13>-0.1912</PDBx:U13>
         <PDBx:U22>0.9131</PDBx:U22>
         <PDBx:U23>0.1262</PDBx:U23>
         <PDBx:U33>0.4963</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1405">
         <PDBx:U11>0.4293</PDBx:U11>
         <PDBx:U12>-0.0427</PDBx:U12>
         <PDBx:U13>-0.1908</PDBx:U13>
         <PDBx:U22>0.9519</PDBx:U22>
         <PDBx:U23>0.1181</PDBx:U23>
         <PDBx:U33>0.5382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1406">
         <PDBx:U11>0.4289</PDBx:U11>
         <PDBx:U12>-0.0408</PDBx:U12>
         <PDBx:U13>-0.1898</PDBx:U13>
         <PDBx:U22>0.9507</PDBx:U22>
         <PDBx:U23>0.1195</PDBx:U23>
         <PDBx:U33>0.5384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1407">
         <PDBx:U11>0.4113</PDBx:U11>
         <PDBx:U12>-0.0653</PDBx:U12>
         <PDBx:U13>-0.1790</PDBx:U13>
         <PDBx:U22>0.8905</PDBx:U22>
         <PDBx:U23>0.1036</PDBx:U23>
         <PDBx:U33>0.5166</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1408">
         <PDBx:U11>0.4106</PDBx:U11>
         <PDBx:U12>-0.0642</PDBx:U12>
         <PDBx:U13>-0.1783</PDBx:U13>
         <PDBx:U22>0.8900</PDBx:U22>
         <PDBx:U23>0.1046</PDBx:U23>
         <PDBx:U33>0.5169</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1409">
         <PDBx:U11>0.3842</PDBx:U11>
         <PDBx:U12>-0.0615</PDBx:U12>
         <PDBx:U13>-0.1709</PDBx:U13>
         <PDBx:U22>0.8114</PDBx:U22>
         <PDBx:U23>0.1030</PDBx:U23>
         <PDBx:U33>0.4611</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1410">
         <PDBx:U11>0.3866</PDBx:U11>
         <PDBx:U12>-0.0600</PDBx:U12>
         <PDBx:U13>-0.1698</PDBx:U13>
         <PDBx:U22>0.8143</PDBx:U22>
         <PDBx:U23>0.1044</PDBx:U23>
         <PDBx:U33>0.4656</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1411">
         <PDBx:U11>0.4276</PDBx:U11>
         <PDBx:U12>-0.0177</PDBx:U12>
         <PDBx:U13>-0.1832</PDBx:U13>
         <PDBx:U22>0.9909</PDBx:U22>
         <PDBx:U23>0.1388</PDBx:U23>
         <PDBx:U33>0.5761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1412">
         <PDBx:U11>0.4284</PDBx:U11>
         <PDBx:U12>-0.0132</PDBx:U12>
         <PDBx:U13>-0.1814</PDBx:U13>
         <PDBx:U22>0.9869</PDBx:U22>
         <PDBx:U23>0.1414</PDBx:U23>
         <PDBx:U33>0.5751</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1413">
         <PDBx:U11>0.3969</PDBx:U11>
         <PDBx:U12>0.0009</PDBx:U12>
         <PDBx:U13>-0.1651</PDBx:U13>
         <PDBx:U22>0.9213</PDBx:U22>
         <PDBx:U23>0.1498</PDBx:U23>
         <PDBx:U33>0.5416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1414">
         <PDBx:U11>0.4548</PDBx:U11>
         <PDBx:U12>0.0021</PDBx:U12>
         <PDBx:U13>-0.1944</PDBx:U13>
         <PDBx:U22>1.0657</PDBx:U22>
         <PDBx:U23>0.1526</PDBx:U23>
         <PDBx:U33>0.6150</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1415">
         <PDBx:U11>0.4621</PDBx:U11>
         <PDBx:U12>0.0096</PDBx:U12>
         <PDBx:U13>-0.1934</PDBx:U13>
         <PDBx:U22>1.0626</PDBx:U22>
         <PDBx:U23>0.1566</PDBx:U23>
         <PDBx:U33>0.6135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1416">
         <PDBx:U11>0.4074</PDBx:U11>
         <PDBx:U12>-0.0299</PDBx:U12>
         <PDBx:U13>-0.1724</PDBx:U13>
         <PDBx:U22>0.9889</PDBx:U22>
         <PDBx:U23>0.1354</PDBx:U23>
         <PDBx:U33>0.5924</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1417">
         <PDBx:U11>0.4466</PDBx:U11>
         <PDBx:U12>-0.0891</PDBx:U12>
         <PDBx:U13>-0.1775</PDBx:U13>
         <PDBx:U22>0.9462</PDBx:U22>
         <PDBx:U23>0.0928</PDBx:U23>
         <PDBx:U33>0.5802</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1418">
         <PDBx:U11>0.4264</PDBx:U11>
         <PDBx:U12>-0.1107</PDBx:U12>
         <PDBx:U13>-0.1654</PDBx:U13>
         <PDBx:U22>0.8850</PDBx:U22>
         <PDBx:U23>0.0813</PDBx:U23>
         <PDBx:U33>0.5590</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1419">
         <PDBx:U11>0.3570</PDBx:U11>
         <PDBx:U12>-0.0927</PDBx:U12>
         <PDBx:U13>-0.1502</PDBx:U13>
         <PDBx:U22>0.7918</PDBx:U22>
         <PDBx:U23>0.0963</PDBx:U23>
         <PDBx:U33>0.4904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1420">
         <PDBx:U11>0.3751</PDBx:U11>
         <PDBx:U12>-0.1003</PDBx:U12>
         <PDBx:U13>-0.1431</PDBx:U13>
         <PDBx:U22>0.7587</PDBx:U22>
         <PDBx:U23>0.0904</PDBx:U23>
         <PDBx:U33>0.4861</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1421">
         <PDBx:U11>0.4404</PDBx:U11>
         <PDBx:U12>-0.1351</PDBx:U12>
         <PDBx:U13>-0.1633</PDBx:U13>
         <PDBx:U22>0.9274</PDBx:U22>
         <PDBx:U23>0.0724</PDBx:U23>
         <PDBx:U33>0.6073</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1422">
         <PDBx:U11>0.5201</PDBx:U11>
         <PDBx:U12>-0.1640</PDBx:U12>
         <PDBx:U13>-0.1737</PDBx:U13>
         <PDBx:U22>1.0065</PDBx:U22>
         <PDBx:U23>0.0499</PDBx:U23>
         <PDBx:U33>0.6825</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1423">
         <PDBx:U11>0.5521</PDBx:U11>
         <PDBx:U12>-0.1572</PDBx:U12>
         <PDBx:U13>-0.1923</PDBx:U13>
         <PDBx:U22>1.0837</PDBx:U22>
         <PDBx:U23>0.0497</PDBx:U23>
         <PDBx:U33>0.7125</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1424">
         <PDBx:U11>0.5994</PDBx:U11>
         <PDBx:U12>-0.1878</PDBx:U12>
         <PDBx:U13>-0.1670</PDBx:U13>
         <PDBx:U22>1.1018</PDBx:U22>
         <PDBx:U23>0.0434</PDBx:U23>
         <PDBx:U33>0.7955</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1425">
         <PDBx:U11>0.4176</PDBx:U11>
         <PDBx:U12>-0.0676</PDBx:U12>
         <PDBx:U13>-0.1448</PDBx:U13>
         <PDBx:U22>0.8899</PDBx:U22>
         <PDBx:U23>0.1151</PDBx:U23>
         <PDBx:U33>0.5777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1426">
         <PDBx:U11>0.4538</PDBx:U11>
         <PDBx:U12>-0.0469</PDBx:U12>
         <PDBx:U13>-0.1290</PDBx:U13>
         <PDBx:U22>0.9074</PDBx:U22>
         <PDBx:U23>0.1293</PDBx:U23>
         <PDBx:U33>0.6173</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1427">
         <PDBx:U11>0.4023</PDBx:U11>
         <PDBx:U12>-0.0274</PDBx:U12>
         <PDBx:U13>-0.1286</PDBx:U13>
         <PDBx:U22>0.8075</PDBx:U22>
         <PDBx:U23>0.1355</PDBx:U23>
         <PDBx:U33>0.5262</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1428">
         <PDBx:U11>0.3894</PDBx:U11>
         <PDBx:U12>-0.0251</PDBx:U12>
         <PDBx:U13>-0.1137</PDBx:U13>
         <PDBx:U22>0.7409</PDBx:U22>
         <PDBx:U23>0.1328</PDBx:U23>
         <PDBx:U33>0.4940</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1429">
         <PDBx:U11>0.4075</PDBx:U11>
         <PDBx:U12>-0.0196</PDBx:U12>
         <PDBx:U13>-0.1201</PDBx:U13>
         <PDBx:U22>0.9098</PDBx:U22>
         <PDBx:U23>0.1464</PDBx:U23>
         <PDBx:U33>0.6088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1430">
         <PDBx:U11>0.4318</PDBx:U11>
         <PDBx:U12>0.0076</PDBx:U12>
         <PDBx:U13>-0.0997</PDBx:U13>
         <PDBx:U22>0.9095</PDBx:U22>
         <PDBx:U23>0.1591</PDBx:U23>
         <PDBx:U33>0.6346</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1431">
         <PDBx:U11>0.4694</PDBx:U11>
         <PDBx:U12>0.0389</PDBx:U12>
         <PDBx:U13>-0.0879</PDBx:U13>
         <PDBx:U22>0.9919</PDBx:U22>
         <PDBx:U23>0.1743</PDBx:U23>
         <PDBx:U33>0.7094</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1432">
         <PDBx:U11>0.5449</PDBx:U11>
         <PDBx:U12>0.0407</PDBx:U12>
         <PDBx:U13>-0.0961</PDBx:U13>
         <PDBx:U22>1.1157</PDBx:U22>
         <PDBx:U23>0.1764</PDBx:U23>
         <PDBx:U33>0.8076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1433">
         <PDBx:U11>0.4452</PDBx:U11>
         <PDBx:U12>0.0620</PDBx:U12>
         <PDBx:U13>-0.0632</PDBx:U13>
         <PDBx:U22>0.9310</PDBx:U22>
         <PDBx:U23>0.1778</PDBx:U23>
         <PDBx:U33>0.6804</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1434">
         <PDBx:U11>0.3969</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>-0.1386</PDBx:U13>
         <PDBx:U22>0.8056</PDBx:U22>
         <PDBx:U23>0.1393</PDBx:U23>
         <PDBx:U33>0.5025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1435">
         <PDBx:U11>0.4044</PDBx:U11>
         <PDBx:U12>0.0030</PDBx:U12>
         <PDBx:U13>-0.1355</PDBx:U13>
         <PDBx:U22>0.7636</PDBx:U22>
         <PDBx:U23>0.1453</PDBx:U23>
         <PDBx:U33>0.4701</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1436">
         <PDBx:U11>0.3950</PDBx:U11>
         <PDBx:U12>-0.0225</PDBx:U12>
         <PDBx:U13>-0.1376</PDBx:U13>
         <PDBx:U22>0.7069</PDBx:U22>
         <PDBx:U23>0.1267</PDBx:U23>
         <PDBx:U33>0.4266</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1437">
         <PDBx:U11>0.3631</PDBx:U11>
         <PDBx:U12>-0.0156</PDBx:U12>
         <PDBx:U13>-0.1289</PDBx:U13>
         <PDBx:U22>0.6248</PDBx:U22>
         <PDBx:U23>0.1286</PDBx:U23>
         <PDBx:U33>0.3651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1438">
         <PDBx:U11>0.4389</PDBx:U11>
         <PDBx:U12>0.0217</PDBx:U12>
         <PDBx:U13>-0.1450</PDBx:U13>
         <PDBx:U22>0.8160</PDBx:U22>
         <PDBx:U23>0.1550</PDBx:U23>
         <PDBx:U33>0.4942</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1439">
         <PDBx:U11>0.4148</PDBx:U11>
         <PDBx:U12>0.0522</PDBx:U12>
         <PDBx:U13>-0.1411</PDBx:U13>
         <PDBx:U22>0.8315</PDBx:U22>
         <PDBx:U23>0.1753</PDBx:U23>
         <PDBx:U33>0.5015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1440">
         <PDBx:U11>0.5100</PDBx:U11>
         <PDBx:U12>0.0659</PDBx:U12>
         <PDBx:U13>-0.1546</PDBx:U13>
         <PDBx:U22>0.9525</PDBx:U22>
         <PDBx:U23>0.1849</PDBx:U23>
         <PDBx:U33>0.5890</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1441">
         <PDBx:U11>0.5451</PDBx:U11>
         <PDBx:U12>0.0462</PDBx:U12>
         <PDBx:U13>-0.1709</PDBx:U13>
         <PDBx:U22>1.0031</PDBx:U22>
         <PDBx:U23>0.1730</PDBx:U23>
         <PDBx:U33>0.6098</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1442">
         <PDBx:U11>0.5052</PDBx:U11>
         <PDBx:U12>0.1003</PDBx:U12>
         <PDBx:U13>-0.1469</PDBx:U13>
         <PDBx:U22>0.9504</PDBx:U22>
         <PDBx:U23>0.2063</PDBx:U23>
         <PDBx:U33>0.5928</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1443">
         <PDBx:U11>0.3422</PDBx:U11>
         <PDBx:U12>-0.0517</PDBx:U12>
         <PDBx:U13>-0.1468</PDBx:U13>
         <PDBx:U22>0.6671</PDBx:U22>
         <PDBx:U23>0.1077</PDBx:U23>
         <PDBx:U33>0.3790</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1444">
         <PDBx:U11>0.3877</PDBx:U11>
         <PDBx:U12>-0.0750</PDBx:U12>
         <PDBx:U13>-0.1461</PDBx:U13>
         <PDBx:U22>0.6673</PDBx:U22>
         <PDBx:U23>0.0877</PDBx:U23>
         <PDBx:U33>0.3977</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1445">
         <PDBx:U11>0.3545</PDBx:U11>
         <PDBx:U12>-0.0821</PDBx:U12>
         <PDBx:U13>-0.1340</PDBx:U13>
         <PDBx:U22>0.5957</PDBx:U22>
         <PDBx:U23>0.0867</PDBx:U23>
         <PDBx:U33>0.3634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1446">
         <PDBx:U11>0.3905</PDBx:U11>
         <PDBx:U12>-0.0801</PDBx:U12>
         <PDBx:U13>-0.1264</PDBx:U13>
         <PDBx:U22>0.5810</PDBx:U22>
         <PDBx:U23>0.0817</PDBx:U23>
         <PDBx:U33>0.3696</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1447">
         <PDBx:U11>0.4021</PDBx:U11>
         <PDBx:U12>-0.1020</PDBx:U12>
         <PDBx:U13>-0.1544</PDBx:U13>
         <PDBx:U22>0.6984</PDBx:U22>
         <PDBx:U23>0.0676</PDBx:U23>
         <PDBx:U33>0.4217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1448">
         <PDBx:U11>0.3955</PDBx:U11>
         <PDBx:U12>-0.1000</PDBx:U12>
         <PDBx:U13>-0.1686</PDBx:U13>
         <PDBx:U22>0.7203</PDBx:U22>
         <PDBx:U23>0.0631</PDBx:U23>
         <PDBx:U33>0.4047</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1449">
         <PDBx:U11>0.4248</PDBx:U11>
         <PDBx:U12>-0.1276</PDBx:U12>
         <PDBx:U13>-0.1758</PDBx:U13>
         <PDBx:U22>0.7630</PDBx:U22>
         <PDBx:U23>0.0417</PDBx:U23>
         <PDBx:U33>0.4437</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1450">
         <PDBx:U11>0.4412</PDBx:U11>
         <PDBx:U12>-0.1473</PDBx:U12>
         <PDBx:U13>-0.1685</PDBx:U13>
         <PDBx:U22>0.7446</PDBx:U22>
         <PDBx:U23>0.0260</PDBx:U23>
         <PDBx:U33>0.4586</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1451">
         <PDBx:U11>0.3987</PDBx:U11>
         <PDBx:U12>-0.1281</PDBx:U12>
         <PDBx:U13>-0.1898</PDBx:U13>
         <PDBx:U22>0.7854</PDBx:U22>
         <PDBx:U23>0.0416</PDBx:U23>
         <PDBx:U33>0.4279</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1452">
         <PDBx:U11>0.3772</PDBx:U11>
         <PDBx:U12>-0.0883</PDBx:U12>
         <PDBx:U13>-0.1269</PDBx:U13>
         <PDBx:U22>0.6362</PDBx:U22>
         <PDBx:U23>0.0893</PDBx:U23>
         <PDBx:U33>0.4180</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1453">
         <PDBx:U11>0.3445</PDBx:U11>
         <PDBx:U12>-0.0918</PDBx:U12>
         <PDBx:U13>-0.1085</PDBx:U13>
         <PDBx:U22>0.5569</PDBx:U22>
         <PDBx:U23>0.0851</PDBx:U23>
         <PDBx:U33>0.3810</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1454">
         <PDBx:U11>0.3186</PDBx:U11>
         <PDBx:U12>-0.0647</PDBx:U12>
         <PDBx:U13>-0.0917</PDBx:U13>
         <PDBx:U22>0.5007</PDBx:U22>
         <PDBx:U23>0.0950</PDBx:U23>
         <PDBx:U33>0.3424</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1455">
         <PDBx:U11>0.3073</PDBx:U11>
         <PDBx:U12>-0.0665</PDBx:U12>
         <PDBx:U13>-0.0798</PDBx:U13>
         <PDBx:U22>0.4435</PDBx:U22>
         <PDBx:U23>0.0891</PDBx:U23>
         <PDBx:U33>0.3134</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1456">
         <PDBx:U11>0.4185</PDBx:U11>
         <PDBx:U12>-0.1091</PDBx:U12>
         <PDBx:U13>-0.1032</PDBx:U13>
         <PDBx:U22>0.6544</PDBx:U22>
         <PDBx:U23>0.0846</PDBx:U23>
         <PDBx:U33>0.4876</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1457">
         <PDBx:U11>0.5327</PDBx:U11>
         <PDBx:U12>-0.0925</PDBx:U12>
         <PDBx:U13>-0.0959</PDBx:U13>
         <PDBx:U22>0.8146</PDBx:U22>
         <PDBx:U23>0.0991</PDBx:U23>
         <PDBx:U33>0.6337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1458">
         <PDBx:U11>0.5808</PDBx:U11>
         <PDBx:U12>-0.1054</PDBx:U12>
         <PDBx:U13>-0.1020</PDBx:U13>
         <PDBx:U22>0.9224</PDBx:U22>
         <PDBx:U23>0.1019</PDBx:U23>
         <PDBx:U33>0.7202</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1459">
         <PDBx:U11>0.5780</PDBx:U11>
         <PDBx:U12>-0.0643</PDBx:U12>
         <PDBx:U13>-0.0813</PDBx:U13>
         <PDBx:U22>0.8548</PDBx:U22>
         <PDBx:U23>0.1101</PDBx:U23>
         <PDBx:U33>0.6797</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1460">
         <PDBx:U11>0.5864</PDBx:U11>
         <PDBx:U12>-0.0835</PDBx:U12>
         <PDBx:U13>-0.0912</PDBx:U13>
         <PDBx:U22>0.9613</PDBx:U22>
         <PDBx:U23>0.1151</PDBx:U23>
         <PDBx:U33>0.7502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1461">
         <PDBx:U11>0.5968</PDBx:U11>
         <PDBx:U12>-0.0577</PDBx:U12>
         <PDBx:U13>-0.0781</PDBx:U13>
         <PDBx:U22>0.9303</PDBx:U22>
         <PDBx:U23>0.1197</PDBx:U23>
         <PDBx:U33>0.7371</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1462">
         <PDBx:U11>0.3400</PDBx:U11>
         <PDBx:U12>-0.0398</PDBx:U12>
         <PDBx:U13>-0.0906</PDBx:U13>
         <PDBx:U22>0.5476</PDBx:U22>
         <PDBx:U23>0.1097</PDBx:U23>
         <PDBx:U33>0.3733</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1463">
         <PDBx:U11>0.3612</PDBx:U11>
         <PDBx:U12>-0.0150</PDBx:U12>
         <PDBx:U13>-0.0733</PDBx:U13>
         <PDBx:U22>0.5332</PDBx:U22>
         <PDBx:U23>0.1172</PDBx:U23>
         <PDBx:U33>0.3805</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1464">
         <PDBx:U11>0.3848</PDBx:U11>
         <PDBx:U12>-0.0126</PDBx:U12>
         <PDBx:U13>-0.0733</PDBx:U13>
         <PDBx:U22>0.5096</PDBx:U22>
         <PDBx:U23>0.1137</PDBx:U23>
         <PDBx:U33>0.3658</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1465">
         <PDBx:U11>0.4060</PDBx:U11>
         <PDBx:U12>-0.0096</PDBx:U12>
         <PDBx:U13>-0.0586</PDBx:U13>
         <PDBx:U22>0.4852</PDBx:U22>
         <PDBx:U23>0.1090</PDBx:U23>
         <PDBx:U33>0.3694</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1466">
         <PDBx:U11>0.3731</PDBx:U11>
         <PDBx:U12>0.0142</PDBx:U12>
         <PDBx:U13>-0.0705</PDBx:U13>
         <PDBx:U22>0.5790</PDBx:U22>
         <PDBx:U23>0.1351</PDBx:U23>
         <PDBx:U33>0.4129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1467">
         <PDBx:U11>0.4027</PDBx:U11>
         <PDBx:U12>0.0173</PDBx:U12>
         <PDBx:U13>-0.0631</PDBx:U13>
         <PDBx:U22>0.6529</PDBx:U22>
         <PDBx:U23>0.1390</PDBx:U23>
         <PDBx:U33>0.4823</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1468">
         <PDBx:U11>0.4272</PDBx:U11>
         <PDBx:U12>0.0521</PDBx:U12>
         <PDBx:U13>-0.0557</PDBx:U13>
         <PDBx:U22>0.7042</PDBx:U22>
         <PDBx:U23>0.1565</PDBx:U23>
         <PDBx:U33>0.5279</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1469">
         <PDBx:U11>0.4671</PDBx:U11>
         <PDBx:U12>0.0750</PDBx:U12>
         <PDBx:U13>-0.0543</PDBx:U13>
         <PDBx:U22>0.7209</PDBx:U22>
         <PDBx:U23>0.1673</PDBx:U23>
         <PDBx:U33>0.5502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1470">
         <PDBx:U11>0.3877</PDBx:U11>
         <PDBx:U12>0.0569</PDBx:U12>
         <PDBx:U13>-0.0491</PDBx:U13>
         <PDBx:U22>0.7129</PDBx:U22>
         <PDBx:U23>0.1605</PDBx:U23>
         <PDBx:U33>0.5272</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1471">
         <PDBx:U11>0.4089</PDBx:U11>
         <PDBx:U12>-0.0154</PDBx:U12>
         <PDBx:U13>-0.0896</PDBx:U13>
         <PDBx:U22>0.5485</PDBx:U22>
         <PDBx:U23>0.1155</PDBx:U23>
         <PDBx:U33>0.3770</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1472">
         <PDBx:U11>0.3785</PDBx:U11>
         <PDBx:U12>-0.0147</PDBx:U12>
         <PDBx:U13>-0.0889</PDBx:U13>
         <PDBx:U22>0.4790</PDBx:U22>
         <PDBx:U23>0.1128</PDBx:U23>
         <PDBx:U33>0.3098</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1473">
         <PDBx:U11>0.3782</PDBx:U11>
         <PDBx:U12>-0.0367</PDBx:U12>
         <PDBx:U13>-0.0852</PDBx:U13>
         <PDBx:U22>0.4432</PDBx:U22>
         <PDBx:U23>0.0934</PDBx:U23>
         <PDBx:U33>0.2952</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1474">
         <PDBx:U11>0.3992</PDBx:U11>
         <PDBx:U12>-0.0348</PDBx:U12>
         <PDBx:U13>-0.0746</PDBx:U13>
         <PDBx:U22>0.4229</PDBx:U22>
         <PDBx:U23>0.0897</PDBx:U23>
         <PDBx:U33>0.2939</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1475">
         <PDBx:U11>0.3770</PDBx:U11>
         <PDBx:U12>-0.0139</PDBx:U12>
         <PDBx:U13>-0.1075</PDBx:U13>
         <PDBx:U22>0.5079</PDBx:U22>
         <PDBx:U23>0.1187</PDBx:U23>
         <PDBx:U33>0.2950</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1476">
         <PDBx:U11>0.4126</PDBx:U11>
         <PDBx:U12>-0.0111</PDBx:U12>
         <PDBx:U13>-0.1027</PDBx:U13>
         <PDBx:U22>0.5045</PDBx:U22>
         <PDBx:U23>0.1164</PDBx:U23>
         <PDBx:U33>0.2924</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1477">
         <PDBx:U11>0.3918</PDBx:U11>
         <PDBx:U12>-0.0057</PDBx:U12>
         <PDBx:U13>-0.1145</PDBx:U13>
         <PDBx:U22>0.5087</PDBx:U22>
         <PDBx:U23>0.1181</PDBx:U23>
         <PDBx:U33>0.2599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1478">
         <PDBx:U11>0.4651</PDBx:U11>
         <PDBx:U12>-0.0021</PDBx:U12>
         <PDBx:U13>-0.1071</PDBx:U13>
         <PDBx:U22>0.5462</PDBx:U22>
         <PDBx:U23>0.1171</PDBx:U23>
         <PDBx:U33>0.2970</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1479">
         <PDBx:U11>0.5407</PDBx:U11>
         <PDBx:U12>0.0177</PDBx:U12>
         <PDBx:U13>-0.0957</PDBx:U13>
         <PDBx:U22>0.5933</PDBx:U22>
         <PDBx:U23>0.1335</PDBx:U23>
         <PDBx:U33>0.3566</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1480">
         <PDBx:U11>0.5233</PDBx:U11>
         <PDBx:U12>0.0371</PDBx:U12>
         <PDBx:U13>-0.0900</PDBx:U13>
         <PDBx:U22>0.5760</PDBx:U22>
         <PDBx:U23>0.1509</PDBx:U23>
         <PDBx:U33>0.3571</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1481">
         <PDBx:U11>0.6059</PDBx:U11>
         <PDBx:U12>0.0176</PDBx:U12>
         <PDBx:U13>-0.0882</PDBx:U13>
         <PDBx:U22>0.6285</PDBx:U22>
         <PDBx:U23>0.1319</PDBx:U23>
         <PDBx:U33>0.3895</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1482">
         <PDBx:U11>0.3647</PDBx:U11>
         <PDBx:U12>-0.0575</PDBx:U12>
         <PDBx:U13>-0.0934</PDBx:U13>
         <PDBx:U22>0.4465</PDBx:U22>
         <PDBx:U23>0.0819</PDBx:U23>
         <PDBx:U33>0.2966</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1483">
         <PDBx:U11>0.3943</PDBx:U11>
         <PDBx:U12>-0.0753</PDBx:U12>
         <PDBx:U13>-0.0896</PDBx:U13>
         <PDBx:U22>0.4428</PDBx:U22>
         <PDBx:U23>0.0659</PDBx:U23>
         <PDBx:U33>0.3170</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1484">
         <PDBx:U11>0.3847</PDBx:U11>
         <PDBx:U12>-0.0689</PDBx:U12>
         <PDBx:U13>-0.0726</PDBx:U13>
         <PDBx:U22>0.4012</PDBx:U22>
         <PDBx:U23>0.0668</PDBx:U23>
         <PDBx:U33>0.3064</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1485">
         <PDBx:U11>0.3732</PDBx:U11>
         <PDBx:U12>-0.0710</PDBx:U12>
         <PDBx:U13>-0.0662</PDBx:U13>
         <PDBx:U22>0.3558</PDBx:U22>
         <PDBx:U23>0.0594</PDBx:U23>
         <PDBx:U33>0.2766</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
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         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1502">
         <PDBx:U11>0.5055</PDBx:U11>
         <PDBx:U12>0.0473</PDBx:U12>
         <PDBx:U13>-0.0432</PDBx:U13>
         <PDBx:U22>0.5205</PDBx:U22>
         <PDBx:U23>0.1448</PDBx:U23>
         <PDBx:U33>0.4157</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1503">
         <PDBx:U11>0.4657</PDBx:U11>
         <PDBx:U12>0.0589</PDBx:U12>
         <PDBx:U13>-0.0345</PDBx:U13>
         <PDBx:U22>0.5242</PDBx:U22>
         <PDBx:U23>0.1458</PDBx:U23>
         <PDBx:U33>0.4267</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1504">
         <PDBx:U11>0.4301</PDBx:U11>
         <PDBx:U12>-0.0353</PDBx:U12>
         <PDBx:U13>-0.0431</PDBx:U13>
         <PDBx:U22>0.3673</PDBx:U22>
         <PDBx:U23>0.0771</PDBx:U23>
         <PDBx:U33>0.2964</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1505">
         <PDBx:U11>0.4386</PDBx:U11>
         <PDBx:U12>-0.0450</PDBx:U12>
         <PDBx:U13>-0.0425</PDBx:U13>
         <PDBx:U22>0.3542</PDBx:U22>
         <PDBx:U23>0.0676</PDBx:U23>
         <PDBx:U33>0.2837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1506">
         <PDBx:U11>0.4331</PDBx:U11>
         <PDBx:U12>-0.0571</PDBx:U12>
         <PDBx:U13>-0.0373</PDBx:U13>
         <PDBx:U22>0.3325</PDBx:U22>
         <PDBx:U23>0.0538</PDBx:U23>
         <PDBx:U33>0.2819</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1507">
         <PDBx:U11>0.4244</PDBx:U11>
         <PDBx:U12>-0.0595</PDBx:U12>
         <PDBx:U13>-0.0285</PDBx:U13>
         <PDBx:U22>0.3022</PDBx:U22>
         <PDBx:U23>0.0476</PDBx:U23>
         <PDBx:U33>0.2620</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1508">
         <PDBx:U11>0.4258</PDBx:U11>
         <PDBx:U12>-0.0526</PDBx:U12>
         <PDBx:U13>-0.0574</PDBx:U13>
         <PDBx:U22>0.3612</PDBx:U22>
         <PDBx:U23>0.0641</PDBx:U23>
         <PDBx:U33>0.2627</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1509">
         <PDBx:U11>0.5385</PDBx:U11>
         <PDBx:U12>-0.0408</PDBx:U12>
         <PDBx:U13>-0.0652</PDBx:U13>
         <PDBx:U22>0.4943</PDBx:U22>
         <PDBx:U23>0.0788</PDBx:U23>
         <PDBx:U33>0.3651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1510">
         <PDBx:U11>0.5248</PDBx:U11>
         <PDBx:U12>-0.0514</PDBx:U12>
         <PDBx:U13>-0.0802</PDBx:U13>
         <PDBx:U22>0.5068</PDBx:U22>
         <PDBx:U23>0.0695</PDBx:U23>
         <PDBx:U33>0.3460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1511">
         <PDBx:U11>0.5673</PDBx:U11>
         <PDBx:U12>-0.0287</PDBx:U12>
         <PDBx:U13>-0.0511</PDBx:U13>
         <PDBx:U22>0.4972</PDBx:U22>
         <PDBx:U23>0.0861</PDBx:U23>
         <PDBx:U33>0.3755</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1512">
         <PDBx:U11>0.4297</PDBx:U11>
         <PDBx:U12>-0.0644</PDBx:U12>
         <PDBx:U13>-0.0425</PDBx:U13>
         <PDBx:U22>0.3430</PDBx:U22>
         <PDBx:U23>0.0502</PDBx:U23>
         <PDBx:U33>0.2965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1513">
         <PDBx:U11>0.4141</PDBx:U11>
         <PDBx:U12>-0.0734</PDBx:U12>
         <PDBx:U13>-0.0395</PDBx:U13>
         <PDBx:U22>0.3154</PDBx:U22>
         <PDBx:U23>0.0413</PDBx:U23>
         <PDBx:U33>0.2848</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1514">
         <PDBx:U11>0.3894</PDBx:U11>
         <PDBx:U12>-0.0694</PDBx:U12>
         <PDBx:U13>-0.0275</PDBx:U13>
         <PDBx:U22>0.2786</PDBx:U22>
         <PDBx:U23>0.0414</PDBx:U23>
         <PDBx:U33>0.2588</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1515">
         <PDBx:U11>0.4243</PDBx:U11>
         <PDBx:U12>-0.0716</PDBx:U12>
         <PDBx:U13>-0.0240</PDBx:U13>
         <PDBx:U22>0.3084</PDBx:U22>
         <PDBx:U23>0.0316</PDBx:U23>
         <PDBx:U33>0.2950</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1516">
         <PDBx:U11>0.4345</PDBx:U11>
         <PDBx:U12>-0.0825</PDBx:U12>
         <PDBx:U13>-0.0470</PDBx:U13>
         <PDBx:U22>0.3504</PDBx:U22>
         <PDBx:U23>0.0409</PDBx:U23>
         <PDBx:U33>0.3229</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1517">
         <PDBx:U11>0.4449</PDBx:U11>
         <PDBx:U12>-0.0919</PDBx:U12>
         <PDBx:U13>-0.0586</PDBx:U13>
         <PDBx:U22>0.3693</PDBx:U22>
         <PDBx:U23>0.0352</PDBx:U23>
         <PDBx:U33>0.3344</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1518">
         <PDBx:U11>0.4295</PDBx:U11>
         <PDBx:U12>-0.1040</PDBx:U12>
         <PDBx:U13>-0.0629</PDBx:U13>
         <PDBx:U22>0.3612</PDBx:U22>
         <PDBx:U23>0.0346</PDBx:U23>
         <PDBx:U33>0.3377</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1519">
         <PDBx:U11>0.4268</PDBx:U11>
         <PDBx:U12>-0.0949</PDBx:U12>
         <PDBx:U13>-0.0582</PDBx:U13>
         <PDBx:U22>0.3312</PDBx:U22>
         <PDBx:U23>0.0236</PDBx:U23>
         <PDBx:U33>0.2998</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1520">
         <PDBx:U11>0.3671</PDBx:U11>
         <PDBx:U12>-0.0599</PDBx:U12>
         <PDBx:U13>-0.0209</PDBx:U13>
         <PDBx:U22>0.2602</PDBx:U22>
         <PDBx:U23>0.0485</PDBx:U23>
         <PDBx:U33>0.2400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1521">
         <PDBx:U11>0.3791</PDBx:U11>
         <PDBx:U12>-0.0573</PDBx:U12>
         <PDBx:U13>-0.0080</PDBx:U13>
         <PDBx:U22>0.2583</PDBx:U22>
         <PDBx:U23>0.0450</PDBx:U23>
         <PDBx:U33>0.2473</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1522">
         <PDBx:U11>0.4056</PDBx:U11>
         <PDBx:U12>-0.0559</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.2655</PDBx:U22>
         <PDBx:U23>0.0371</PDBx:U23>
         <PDBx:U33>0.2632</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1523">
         <PDBx:U11>0.4412</PDBx:U11>
         <PDBx:U12>-0.0604</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.2942</PDBx:U22>
         <PDBx:U23>0.0271</PDBx:U23>
         <PDBx:U33>0.2963</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1524">
         <PDBx:U11>0.3833</PDBx:U11>
         <PDBx:U12>-0.0449</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.2695</PDBx:U22>
         <PDBx:U23>0.0521</PDBx:U23>
         <PDBx:U33>0.2593</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1525">
         <PDBx:U11>0.3850</PDBx:U11>
         <PDBx:U12>-0.0463</PDBx:U12>
         <PDBx:U13>-0.0021</PDBx:U13>
         <PDBx:U22>0.2982</PDBx:U22>
         <PDBx:U23>0.0556</PDBx:U23>
         <PDBx:U33>0.2787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1526">
         <PDBx:U11>0.4552</PDBx:U11>
         <PDBx:U12>-0.0313</PDBx:U12>
         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.3763</PDBx:U22>
         <PDBx:U23>0.0610</PDBx:U23>
         <PDBx:U33>0.3577</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1527">
         <PDBx:U11>0.3497</PDBx:U11>
         <PDBx:U12>-0.0577</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.2609</PDBx:U22>
         <PDBx:U23>0.0484</PDBx:U23>
         <PDBx:U33>0.2393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1528">
         <PDBx:U11>0.4256</PDBx:U11>
         <PDBx:U12>-0.0510</PDBx:U12>
         <PDBx:U13>-0.0015</PDBx:U13>
         <PDBx:U22>0.2803</PDBx:U22>
         <PDBx:U23>0.0423</PDBx:U23>
         <PDBx:U33>0.2761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1529">
         <PDBx:U11>0.4593</PDBx:U11>
         <PDBx:U12>-0.0513</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.2986</PDBx:U22>
         <PDBx:U23>0.0368</PDBx:U23>
         <PDBx:U33>0.3011</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1530">
         <PDBx:U11>0.4305</PDBx:U11>
         <PDBx:U12>-0.0620</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.2749</PDBx:U22>
         <PDBx:U23>0.0238</PDBx:U23>
         <PDBx:U33>0.2731</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1531">
         <PDBx:U11>0.4167</PDBx:U11>
         <PDBx:U12>-0.0660</PDBx:U12>
         <PDBx:U13>0.0120</PDBx:U13>
         <PDBx:U22>0.2534</PDBx:U22>
         <PDBx:U23>0.0164</PDBx:U23>
         <PDBx:U33>0.2553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1532">
         <PDBx:U11>0.4942</PDBx:U11>
         <PDBx:U12>-0.0442</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.3309</PDBx:U22>
         <PDBx:U23>0.0478</PDBx:U23>
         <PDBx:U33>0.3259</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1533">
         <PDBx:U11>0.5608</PDBx:U11>
         <PDBx:U12>-0.0289</PDBx:U12>
         <PDBx:U13>0.0087</PDBx:U13>
         <PDBx:U22>0.3927</PDBx:U22>
         <PDBx:U23>0.0641</PDBx:U23>
         <PDBx:U33>0.3919</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1534">
         <PDBx:U11>0.5066</PDBx:U11>
         <PDBx:U12>-0.0478</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>0.3295</PDBx:U22>
         <PDBx:U23>0.0426</PDBx:U23>
         <PDBx:U33>0.3294</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1535">
         <PDBx:U11>0.5754</PDBx:U11>
         <PDBx:U12>-0.0191</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.4132</PDBx:U22>
         <PDBx:U23>0.0792</PDBx:U23>
         <PDBx:U33>0.3968</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1536">
         <PDBx:U11>0.3653</PDBx:U11>
         <PDBx:U12>-0.0667</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.2224</PDBx:U22>
         <PDBx:U23>0.0222</PDBx:U23>
         <PDBx:U33>0.2129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1537">
         <PDBx:U11>0.3928</PDBx:U11>
         <PDBx:U12>-0.0731</PDBx:U12>
         <PDBx:U13>-0.0087</PDBx:U13>
         <PDBx:U22>0.2547</PDBx:U22>
         <PDBx:U23>0.0133</PDBx:U23>
         <PDBx:U33>0.2419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1538">
         <PDBx:U11>0.3873</PDBx:U11>
         <PDBx:U12>-0.0749</PDBx:U12>
         <PDBx:U13>-0.0045</PDBx:U13>
         <PDBx:U22>0.2557</PDBx:U22>
         <PDBx:U23>0.0081</PDBx:U23>
         <PDBx:U33>0.2432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1539">
         <PDBx:U11>0.3748</PDBx:U11>
         <PDBx:U12>-0.0787</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.2479</PDBx:U22>
         <PDBx:U23>0.0027</PDBx:U23>
         <PDBx:U33>0.2322</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1540">
         <PDBx:U11>0.3718</PDBx:U11>
         <PDBx:U12>-0.0759</PDBx:U12>
         <PDBx:U13>-0.0193</PDBx:U13>
         <PDBx:U22>0.2409</PDBx:U22>
         <PDBx:U23>0.0141</PDBx:U23>
         <PDBx:U33>0.2261</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1541">
         <PDBx:U11>0.4017</PDBx:U11>
         <PDBx:U12>-0.0806</PDBx:U12>
         <PDBx:U13>-0.0255</PDBx:U13>
         <PDBx:U22>0.2629</PDBx:U22>
         <PDBx:U23>0.0168</PDBx:U23>
         <PDBx:U33>0.2424</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1542">
         <PDBx:U11>0.4309</PDBx:U11>
         <PDBx:U12>-0.0833</PDBx:U12>
         <PDBx:U13>-0.0330</PDBx:U13>
         <PDBx:U22>0.2987</PDBx:U22>
         <PDBx:U23>0.0112</PDBx:U23>
         <PDBx:U33>0.2814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1543">
         <PDBx:U11>0.4300</PDBx:U11>
         <PDBx:U12>-0.0821</PDBx:U12>
         <PDBx:U13>-0.0183</PDBx:U13>
         <PDBx:U22>0.2797</PDBx:U22>
         <PDBx:U23>0.0145</PDBx:U23>
         <PDBx:U33>0.2520</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1544">
         <PDBx:U11>0.3560</PDBx:U11>
         <PDBx:U12>-0.0738</PDBx:U12>
         <PDBx:U13>-0.0034</PDBx:U13>
         <PDBx:U22>0.2253</PDBx:U22>
         <PDBx:U23>0.0105</PDBx:U23>
         <PDBx:U33>0.2146</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1545">
         <PDBx:U11>0.3892</PDBx:U11>
         <PDBx:U12>-0.0792</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.2619</PDBx:U22>
         <PDBx:U23>0.0054</PDBx:U23>
         <PDBx:U33>0.2463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1546">
         <PDBx:U11>0.3854</PDBx:U11>
         <PDBx:U12>-0.0793</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.2582</PDBx:U22>
         <PDBx:U23>0.0053</PDBx:U23>
         <PDBx:U33>0.2425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1547">
         <PDBx:U11>0.3769</PDBx:U11>
         <PDBx:U12>-0.0831</PDBx:U12>
         <PDBx:U13>0.0115</PDBx:U13>
         <PDBx:U22>0.2400</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.2264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1548">
         <PDBx:U11>0.3768</PDBx:U11>
         <PDBx:U12>-0.0907</PDBx:U12>
         <PDBx:U13>0.0134</PDBx:U13>
         <PDBx:U22>0.2491</PDBx:U22>
         <PDBx:U23>-0.0090</PDBx:U23>
         <PDBx:U33>0.2272</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1549">
         <PDBx:U11>0.3737</PDBx:U11>
         <PDBx:U12>-0.0793</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.2455</PDBx:U22>
         <PDBx:U23>0.0094</PDBx:U23>
         <PDBx:U33>0.2294</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1550">
         <PDBx:U11>0.3737</PDBx:U11>
         <PDBx:U12>-0.0795</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.2462</PDBx:U22>
         <PDBx:U23>0.0093</PDBx:U23>
         <PDBx:U33>0.2297</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1551">
         <PDBx:U11>0.3808</PDBx:U11>
         <PDBx:U12>-0.0884</PDBx:U12>
         <PDBx:U13>0.0078</PDBx:U13>
         <PDBx:U22>0.2518</PDBx:U22>
         <PDBx:U23>0.0023</PDBx:U23>
         <PDBx:U33>0.2268</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1552">
         <PDBx:U11>0.3292</PDBx:U11>
         <PDBx:U12>-0.0790</PDBx:U12>
         <PDBx:U13>-0.0075</PDBx:U13>
         <PDBx:U22>0.2160</PDBx:U22>
         <PDBx:U23>0.0166</PDBx:U23>
         <PDBx:U33>0.1951</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1553">
         <PDBx:U11>0.3776</PDBx:U11>
         <PDBx:U12>-0.0783</PDBx:U12>
         <PDBx:U13>0.0188</PDBx:U13>
         <PDBx:U22>0.2234</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.2217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1554">
         <PDBx:U11>0.3711</PDBx:U11>
         <PDBx:U12>-0.0820</PDBx:U12>
         <PDBx:U13>0.0310</PDBx:U13>
         <PDBx:U22>0.2029</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>0.2087</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1555">
         <PDBx:U11>0.3713</PDBx:U11>
         <PDBx:U12>-0.0821</PDBx:U12>
         <PDBx:U13>0.0309</PDBx:U13>
         <PDBx:U22>0.2034</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.2090</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1556">
         <PDBx:U11>0.3514</PDBx:U11>
         <PDBx:U12>-0.0870</PDBx:U12>
         <PDBx:U13>0.0313</PDBx:U13>
         <PDBx:U22>0.1907</PDBx:U22>
         <PDBx:U23>-0.0093</PDBx:U23>
         <PDBx:U33>0.1906</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1557">
         <PDBx:U11>0.4004</PDBx:U11>
         <PDBx:U12>-0.0954</PDBx:U12>
         <PDBx:U13>0.0392</PDBx:U13>
         <PDBx:U22>0.2399</PDBx:U22>
         <PDBx:U23>-0.0166</PDBx:U23>
         <PDBx:U33>0.2395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1558">
         <PDBx:U11>0.3933</PDBx:U11>
         <PDBx:U12>-0.0730</PDBx:U12>
         <PDBx:U13>0.0394</PDBx:U13>
         <PDBx:U22>0.2008</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.2251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1559">
         <PDBx:U11>0.4029</PDBx:U11>
         <PDBx:U12>-0.0734</PDBx:U12>
         <PDBx:U13>0.0398</PDBx:U13>
         <PDBx:U22>0.2102</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.2345</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1560">
         <PDBx:U11>0.4398</PDBx:U11>
         <PDBx:U12>-0.0766</PDBx:U12>
         <PDBx:U13>0.0531</PDBx:U13>
         <PDBx:U22>0.2278</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.2650</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1561">
         <PDBx:U11>0.4480</PDBx:U11>
         <PDBx:U12>-0.0674</PDBx:U12>
         <PDBx:U13>0.0428</PDBx:U13>
         <PDBx:U22>0.2464</PDBx:U22>
         <PDBx:U23>0.0038</PDBx:U23>
         <PDBx:U33>0.2785</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1562">
         <PDBx:U11>0.4590</PDBx:U11>
         <PDBx:U12>-0.0747</PDBx:U12>
         <PDBx:U13>0.0566</PDBx:U13>
         <PDBx:U22>0.2375</PDBx:U22>
         <PDBx:U23>0.0021</PDBx:U23>
         <PDBx:U33>0.2806</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1563">
         <PDBx:U11>0.5171</PDBx:U11>
         <PDBx:U12>-0.0585</PDBx:U12>
         <PDBx:U13>0.0352</PDBx:U13>
         <PDBx:U22>0.3233</PDBx:U22>
         <PDBx:U23>0.0161</PDBx:U23>
         <PDBx:U33>0.3529</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1564">
         <PDBx:U11>0.4585</PDBx:U11>
         <PDBx:U12>-0.0838</PDBx:U12>
         <PDBx:U13>0.0648</PDBx:U13>
         <PDBx:U22>0.2342</PDBx:U22>
         <PDBx:U23>-0.0138</PDBx:U23>
         <PDBx:U33>0.2796</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1565">
         <PDBx:U11>0.5599</PDBx:U11>
         <PDBx:U12>-0.0701</PDBx:U12>
         <PDBx:U13>0.0545</PDBx:U13>
         <PDBx:U22>0.3427</PDBx:U22>
         <PDBx:U23>-0.0038</PDBx:U23>
         <PDBx:U33>0.3834</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1566">
         <PDBx:U11>0.4660</PDBx:U11>
         <PDBx:U12>-0.0802</PDBx:U12>
         <PDBx:U13>0.0700</PDBx:U13>
         <PDBx:U22>0.2259</PDBx:U22>
         <PDBx:U23>-0.0029</PDBx:U23>
         <PDBx:U33>0.2829</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1567">
         <PDBx:U11>0.5516</PDBx:U11>
         <PDBx:U12>-0.0545</PDBx:U12>
         <PDBx:U13>0.0429</PDBx:U13>
         <PDBx:U22>0.3479</PDBx:U22>
         <PDBx:U23>0.0183</PDBx:U23>
         <PDBx:U33>0.3844</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1568">
         <PDBx:U11>0.5134</PDBx:U11>
         <PDBx:U12>-0.0860</PDBx:U12>
         <PDBx:U13>0.0751</PDBx:U13>
         <PDBx:U22>0.2714</PDBx:U22>
         <PDBx:U23>-0.0134</PDBx:U23>
         <PDBx:U33>0.3304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1569">
         <PDBx:U11>0.5575</PDBx:U11>
         <PDBx:U12>-0.0614</PDBx:U12>
         <PDBx:U13>0.0556</PDBx:U13>
         <PDBx:U22>0.3359</PDBx:U22>
         <PDBx:U23>0.0050</PDBx:U23>
         <PDBx:U33>0.3813</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1570">
         <PDBx:U11>0.3658</PDBx:U11>
         <PDBx:U12>-0.0835</PDBx:U12>
         <PDBx:U13>0.0238</PDBx:U13>
         <PDBx:U22>0.2105</PDBx:U22>
         <PDBx:U23>-0.0044</PDBx:U23>
         <PDBx:U33>0.2059</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1571">
         <PDBx:U11>0.3988</PDBx:U11>
         <PDBx:U12>-0.0892</PDBx:U12>
         <PDBx:U13>0.0259</PDBx:U13>
         <PDBx:U22>0.2486</PDBx:U22>
         <PDBx:U23>-0.0076</PDBx:U23>
         <PDBx:U33>0.2380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1572">
         <PDBx:U11>0.3312</PDBx:U11>
         <PDBx:U12>-0.0955</PDBx:U12>
         <PDBx:U13>0.0231</PDBx:U13>
         <PDBx:U22>0.2024</PDBx:U22>
         <PDBx:U23>-0.0137</PDBx:U23>
         <PDBx:U33>0.1836</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1573">
         <PDBx:U11>0.3755</PDBx:U11>
         <PDBx:U12>-0.1037</PDBx:U12>
         <PDBx:U13>0.0292</PDBx:U13>
         <PDBx:U22>0.2542</PDBx:U22>
         <PDBx:U23>-0.0199</PDBx:U23>
         <PDBx:U33>0.2320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1574">
         <PDBx:U11>0.4345</PDBx:U11>
         <PDBx:U12>-0.0860</PDBx:U12>
         <PDBx:U13>0.0197</PDBx:U13>
         <PDBx:U22>0.2815</PDBx:U22>
         <PDBx:U23>-0.0026</PDBx:U23>
         <PDBx:U33>0.2668</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1575">
         <PDBx:U11>0.4360</PDBx:U11>
         <PDBx:U12>-0.0802</PDBx:U12>
         <PDBx:U13>0.0225</PDBx:U13>
         <PDBx:U22>0.2658</PDBx:U22>
         <PDBx:U23>0.0060</PDBx:U23>
         <PDBx:U33>0.2565</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1576">
         <PDBx:U11>0.4191</PDBx:U11>
         <PDBx:U12>-0.0937</PDBx:U12>
         <PDBx:U13>0.0238</PDBx:U13>
         <PDBx:U22>0.2713</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.2496</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1577">
         <PDBx:U11>0.4468</PDBx:U11>
         <PDBx:U12>-0.0792</PDBx:U12>
         <PDBx:U13>0.0159</PDBx:U13>
         <PDBx:U22>0.2760</PDBx:U22>
         <PDBx:U23>0.0115</PDBx:U23>
         <PDBx:U33>0.2559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1578">
         <PDBx:U11>0.3269</PDBx:U11>
         <PDBx:U12>-0.0923</PDBx:U12>
         <PDBx:U13>0.0138</PDBx:U13>
         <PDBx:U22>0.2088</PDBx:U22>
         <PDBx:U23>-0.0115</PDBx:U23>
         <PDBx:U33>0.1872</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1579">
         <PDBx:U11>0.3335</PDBx:U11>
         <PDBx:U12>-0.0975</PDBx:U12>
         <PDBx:U13>0.0089</PDBx:U13>
         <PDBx:U22>0.2354</PDBx:U22>
         <PDBx:U23>-0.0156</PDBx:U23>
         <PDBx:U33>0.2064</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1580">
         <PDBx:U11>0.3032</PDBx:U11>
         <PDBx:U12>-0.1068</PDBx:U12>
         <PDBx:U13>0.0155</PDBx:U13>
         <PDBx:U22>0.2124</PDBx:U22>
         <PDBx:U23>-0.0234</PDBx:U23>
         <PDBx:U33>0.1764</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1581">
         <PDBx:U11>0.3651</PDBx:U11>
         <PDBx:U12>-0.1149</PDBx:U12>
         <PDBx:U13>0.0156</PDBx:U13>
         <PDBx:U22>0.2935</PDBx:U22>
         <PDBx:U23>-0.0304</PDBx:U23>
         <PDBx:U33>0.2484</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1582">
         <PDBx:U11>0.3622</PDBx:U11>
         <PDBx:U12>-0.0937</PDBx:U12>
         <PDBx:U13>-0.0018</PDBx:U13>
         <PDBx:U22>0.2687</PDBx:U22>
         <PDBx:U23>-0.0097</PDBx:U23>
         <PDBx:U33>0.2381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1583">
         <PDBx:U11>0.3585</PDBx:U11>
         <PDBx:U12>-0.0999</PDBx:U12>
         <PDBx:U13>-0.0096</PDBx:U13>
         <PDBx:U22>0.2859</PDBx:U22>
         <PDBx:U23>-0.0123</PDBx:U23>
         <PDBx:U33>0.2431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1584">
         <PDBx:U11>0.3773</PDBx:U11>
         <PDBx:U12>-0.0990</PDBx:U12>
         <PDBx:U13>-0.0168</PDBx:U13>
         <PDBx:U22>0.3109</PDBx:U22>
         <PDBx:U23>-0.0127</PDBx:U23>
         <PDBx:U33>0.2728</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1585">
         <PDBx:U11>0.4519</PDBx:U11>
         <PDBx:U12>-0.0899</PDBx:U12>
         <PDBx:U13>-0.0229</PDBx:U13>
         <PDBx:U22>0.3714</PDBx:U22>
         <PDBx:U23>-0.0035</PDBx:U23>
         <PDBx:U33>0.3483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1586">
         <PDBx:U11>0.4680</PDBx:U11>
         <PDBx:U12>-0.0808</PDBx:U12>
         <PDBx:U13>-0.0299</PDBx:U13>
         <PDBx:U22>0.3940</PDBx:U22>
         <PDBx:U23>0.0028</PDBx:U23>
         <PDBx:U33>0.3772</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1587">
         <PDBx:U11>0.4590</PDBx:U11>
         <PDBx:U12>-0.0768</PDBx:U12>
         <PDBx:U13>-0.0333</PDBx:U13>
         <PDBx:U22>0.4101</PDBx:U22>
         <PDBx:U23>0.0027</PDBx:U23>
         <PDBx:U33>0.3821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1588">
         <PDBx:U11>0.5364</PDBx:U11>
         <PDBx:U12>-0.0758</PDBx:U12>
         <PDBx:U13>-0.0332</PDBx:U13>
         <PDBx:U22>0.4443</PDBx:U22>
         <PDBx:U23>0.0096</PDBx:U23>
         <PDBx:U33>0.4459</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1589">
         <PDBx:U11>0.3395</PDBx:U11>
         <PDBx:U12>-0.1065</PDBx:U12>
         <PDBx:U13>0.0211</PDBx:U13>
         <PDBx:U22>0.2343</PDBx:U22>
         <PDBx:U23>-0.0237</PDBx:U23>
         <PDBx:U33>0.2022</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1590">
         <PDBx:U11>0.3459</PDBx:U11>
         <PDBx:U12>-0.1164</PDBx:U12>
         <PDBx:U13>0.0289</PDBx:U13>
         <PDBx:U22>0.2426</PDBx:U22>
         <PDBx:U23>-0.0332</PDBx:U23>
         <PDBx:U33>0.2064</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1591">
         <PDBx:U11>0.3664</PDBx:U11>
         <PDBx:U12>-0.1242</PDBx:U12>
         <PDBx:U13>0.0386</PDBx:U13>
         <PDBx:U22>0.2604</PDBx:U22>
         <PDBx:U23>-0.0394</PDBx:U23>
         <PDBx:U33>0.2286</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1592">
         <PDBx:U11>0.3590</PDBx:U11>
         <PDBx:U12>-0.1358</PDBx:U12>
         <PDBx:U13>0.0405</PDBx:U13>
         <PDBx:U22>0.2706</PDBx:U22>
         <PDBx:U23>-0.0488</PDBx:U23>
         <PDBx:U33>0.2284</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1593">
         <PDBx:U11>0.3688</PDBx:U11>
         <PDBx:U12>-0.1140</PDBx:U12>
         <PDBx:U13>0.0363</PDBx:U13>
         <PDBx:U22>0.2426</PDBx:U22>
         <PDBx:U23>-0.0336</PDBx:U23>
         <PDBx:U33>0.2163</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1594">
         <PDBx:U11>0.4315</PDBx:U11>
         <PDBx:U12>-0.1251</PDBx:U12>
         <PDBx:U13>0.0454</PDBx:U13>
         <PDBx:U22>0.3038</PDBx:U22>
         <PDBx:U23>-0.0456</PDBx:U23>
         <PDBx:U33>0.2752</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1595">
         <PDBx:U11>0.4381</PDBx:U11>
         <PDBx:U12>-0.1332</PDBx:U12>
         <PDBx:U13>0.0403</PDBx:U13>
         <PDBx:U22>0.3326</PDBx:U22>
         <PDBx:U23>-0.0526</PDBx:U23>
         <PDBx:U33>0.2839</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1596">
         <PDBx:U11>0.4882</PDBx:U11>
         <PDBx:U12>-0.1303</PDBx:U12>
         <PDBx:U13>0.0591</PDBx:U13>
         <PDBx:U22>0.3392</PDBx:U22>
         <PDBx:U23>-0.0523</PDBx:U23>
         <PDBx:U33>0.3257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1597">
         <PDBx:U11>0.4926</PDBx:U11>
         <PDBx:U12>-0.1435</PDBx:U12>
         <PDBx:U13>0.0503</PDBx:U13>
         <PDBx:U22>0.3810</PDBx:U22>
         <PDBx:U23>-0.0648</PDBx:U23>
         <PDBx:U33>0.3337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1598">
         <PDBx:U11>0.4710</PDBx:U11>
         <PDBx:U12>-0.1423</PDBx:U12>
         <PDBx:U13>0.0625</PDBx:U13>
         <PDBx:U22>0.3309</PDBx:U22>
         <PDBx:U23>-0.0649</PDBx:U23>
         <PDBx:U33>0.3074</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1599">
         <PDBx:U11>0.3461</PDBx:U11>
         <PDBx:U12>-0.1191</PDBx:U12>
         <PDBx:U13>0.0444</PDBx:U13>
         <PDBx:U22>0.2200</PDBx:U22>
         <PDBx:U23>-0.0344</PDBx:U23>
         <PDBx:U33>0.2009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1600">
         <PDBx:U11>0.4259</PDBx:U11>
         <PDBx:U12>-0.1275</PDBx:U12>
         <PDBx:U13>0.0550</PDBx:U13>
         <PDBx:U22>0.2937</PDBx:U22>
         <PDBx:U23>-0.0388</PDBx:U23>
         <PDBx:U33>0.2792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1601">
         <PDBx:U11>0.3805</PDBx:U11>
         <PDBx:U12>-0.1356</PDBx:U12>
         <PDBx:U13>0.0521</PDBx:U13>
         <PDBx:U22>0.2765</PDBx:U22>
         <PDBx:U23>-0.0439</PDBx:U23>
         <PDBx:U33>0.2480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1602">
         <PDBx:U11>0.3596</PDBx:U11>
         <PDBx:U12>-0.1485</PDBx:U12>
         <PDBx:U13>0.0591</PDBx:U13>
         <PDBx:U22>0.2662</PDBx:U22>
         <PDBx:U23>-0.0527</PDBx:U23>
         <PDBx:U33>0.2333</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1603">
         <PDBx:U11>0.4224</PDBx:U11>
         <PDBx:U12>-0.1198</PDBx:U12>
         <PDBx:U13>0.0600</PDBx:U13>
         <PDBx:U22>0.2645</PDBx:U22>
         <PDBx:U23>-0.0303</PDBx:U23>
         <PDBx:U33>0.2632</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1604">
         <PDBx:U11>0.4558</PDBx:U11>
         <PDBx:U12>-0.1130</PDBx:U12>
         <PDBx:U13>0.0664</PDBx:U13>
         <PDBx:U22>0.2689</PDBx:U22>
         <PDBx:U23>-0.0260</PDBx:U23>
         <PDBx:U33>0.2862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1605">
         <PDBx:U11>0.5141</PDBx:U11>
         <PDBx:U12>-0.1046</PDBx:U12>
         <PDBx:U13>0.0723</PDBx:U13>
         <PDBx:U22>0.3002</PDBx:U22>
         <PDBx:U23>-0.0132</PDBx:U23>
         <PDBx:U33>0.3326</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1606">
         <PDBx:U11>0.4933</PDBx:U11>
         <PDBx:U12>-0.0940</PDBx:U12>
         <PDBx:U13>0.0570</PDBx:U13>
         <PDBx:U22>0.2936</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.3116</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1607">
         <PDBx:U11>0.3689</PDBx:U11>
         <PDBx:U12>-0.1288</PDBx:U12>
         <PDBx:U13>0.0425</PDBx:U13>
         <PDBx:U22>0.2771</PDBx:U22>
         <PDBx:U23>-0.0392</PDBx:U23>
         <PDBx:U33>0.2431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1608">
         <PDBx:U11>0.3559</PDBx:U11>
         <PDBx:U12>-0.1351</PDBx:U12>
         <PDBx:U13>0.0399</PDBx:U13>
         <PDBx:U22>0.2915</PDBx:U22>
         <PDBx:U23>-0.0448</PDBx:U23>
         <PDBx:U33>0.2466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1609">
         <PDBx:U11>0.3584</PDBx:U11>
         <PDBx:U12>-0.1440</PDBx:U12>
         <PDBx:U13>0.0345</PDBx:U13>
         <PDBx:U22>0.3262</PDBx:U22>
         <PDBx:U23>-0.0532</PDBx:U23>
         <PDBx:U33>0.2653</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1610">
         <PDBx:U11>0.3869</PDBx:U11>
         <PDBx:U12>-0.1555</PDBx:U12>
         <PDBx:U13>0.0389</PDBx:U13>
         <PDBx:U22>0.3787</PDBx:U22>
         <PDBx:U23>-0.0619</PDBx:U23>
         <PDBx:U33>0.3070</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1611">
         <PDBx:U11>0.3752</PDBx:U11>
         <PDBx:U12>-0.1256</PDBx:U12>
         <PDBx:U13>0.0299</PDBx:U13>
         <PDBx:U22>0.3130</PDBx:U22>
         <PDBx:U23>-0.0397</PDBx:U23>
         <PDBx:U33>0.2698</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1612">
         <PDBx:U11>0.3374</PDBx:U11>
         <PDBx:U12>-0.1314</PDBx:U12>
         <PDBx:U13>0.0275</PDBx:U13>
         <PDBx:U22>0.3031</PDBx:U22>
         <PDBx:U23>-0.0473</PDBx:U23>
         <PDBx:U33>0.2512</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1613">
         <PDBx:U11>0.3525</PDBx:U11>
         <PDBx:U12>-0.1394</PDBx:U12>
         <PDBx:U13>0.0249</PDBx:U13>
         <PDBx:U22>0.3240</PDBx:U22>
         <PDBx:U23>-0.0507</PDBx:U23>
         <PDBx:U33>0.2578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1614">
         <PDBx:U11>0.3230</PDBx:U11>
         <PDBx:U12>-0.1471</PDBx:U12>
         <PDBx:U13>0.0173</PDBx:U13>
         <PDBx:U22>0.3277</PDBx:U22>
         <PDBx:U23>-0.0576</PDBx:U23>
         <PDBx:U33>0.2390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1615">
         <PDBx:U11>0.3665</PDBx:U11>
         <PDBx:U12>-0.1617</PDBx:U12>
         <PDBx:U13>0.0273</PDBx:U13>
         <PDBx:U22>0.3767</PDBx:U22>
         <PDBx:U23>-0.0689</PDBx:U23>
         <PDBx:U33>0.2822</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1616">
         <PDBx:U11>0.4197</PDBx:U11>
         <PDBx:U12>-0.1717</PDBx:U12>
         <PDBx:U13>0.0241</PDBx:U13>
         <PDBx:U22>0.4662</PDBx:U22>
         <PDBx:U23>-0.0771</PDBx:U23>
         <PDBx:U33>0.3511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1617">
         <PDBx:U11>0.3049</PDBx:U11>
         <PDBx:U12>-0.1408</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.3074</PDBx:U22>
         <PDBx:U23>-0.0523</PDBx:U23>
         <PDBx:U33>0.2121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1618">
         <PDBx:U11>0.4102</PDBx:U11>
         <PDBx:U12>-0.1301</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.4165</PDBx:U22>
         <PDBx:U23>-0.0423</PDBx:U23>
         <PDBx:U33>0.3208</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1619">
         <PDBx:U11>0.4903</PDBx:U11>
         <PDBx:U12>-0.1290</PDBx:U12>
         <PDBx:U13>-0.0109</PDBx:U13>
         <PDBx:U22>0.5149</PDBx:U22>
         <PDBx:U23>-0.0421</PDBx:U23>
         <PDBx:U33>0.4153</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1620">
         <PDBx:U11>0.4087</PDBx:U11>
         <PDBx:U12>-0.1235</PDBx:U12>
         <PDBx:U13>-0.0083</PDBx:U13>
         <PDBx:U22>0.3986</PDBx:U22>
         <PDBx:U23>-0.0345</PDBx:U23>
         <PDBx:U33>0.3069</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1621">
         <PDBx:U11>0.4059</PDBx:U11>
         <PDBx:U12>-0.1631</PDBx:U12>
         <PDBx:U13>0.0389</PDBx:U13>
         <PDBx:U22>0.3818</PDBx:U22>
         <PDBx:U23>-0.0695</PDBx:U23>
         <PDBx:U33>0.3048</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1622">
         <PDBx:U11>0.4669</PDBx:U11>
         <PDBx:U12>-0.1784</PDBx:U12>
         <PDBx:U13>0.0499</PDBx:U13>
         <PDBx:U22>0.4398</PDBx:U22>
         <PDBx:U23>-0.0812</PDBx:U23>
         <PDBx:U33>0.3629</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1623">
         <PDBx:U11>0.4323</PDBx:U11>
         <PDBx:U12>-0.1883</PDBx:U12>
         <PDBx:U13>0.0587</PDBx:U13>
         <PDBx:U22>0.4116</PDBx:U22>
         <PDBx:U23>-0.0857</PDBx:U23>
         <PDBx:U33>0.3369</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1624">
         <PDBx:U11>0.4744</PDBx:U11>
         <PDBx:U12>-0.2039</PDBx:U12>
         <PDBx:U13>0.0613</PDBx:U13>
         <PDBx:U22>0.4773</PDBx:U22>
         <PDBx:U23>-0.0971</PDBx:U23>
         <PDBx:U33>0.3891</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1625">
         <PDBx:U11>0.5360</PDBx:U11>
         <PDBx:U12>-0.1762</PDBx:U12>
         <PDBx:U13>0.0611</PDBx:U13>
         <PDBx:U22>0.4670</PDBx:U22>
         <PDBx:U23>-0.0804</PDBx:U23>
         <PDBx:U33>0.4129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1626">
         <PDBx:U11>0.5781</PDBx:U11>
         <PDBx:U12>-0.1654</PDBx:U12>
         <PDBx:U13>0.0550</PDBx:U13>
         <PDBx:U22>0.5000</PDBx:U22>
         <PDBx:U23>-0.0750</PDBx:U23>
         <PDBx:U33>0.4463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1627">
         <PDBx:U11>0.6280</PDBx:U11>
         <PDBx:U12>-0.1694</PDBx:U12>
         <PDBx:U13>0.0425</PDBx:U13>
         <PDBx:U22>0.5852</PDBx:U22>
         <PDBx:U23>-0.0797</PDBx:U23>
         <PDBx:U33>0.5031</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1628">
         <PDBx:U11>0.6844</PDBx:U11>
         <PDBx:U12>-0.1871</PDBx:U12>
         <PDBx:U13>0.0469</PDBx:U13>
         <PDBx:U22>0.6561</PDBx:U22>
         <PDBx:U23>-0.0957</PDBx:U23>
         <PDBx:U33>0.5595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1629">
         <PDBx:U11>0.7390</PDBx:U11>
         <PDBx:U12>-0.1901</PDBx:U12>
         <PDBx:U13>0.0329</PDBx:U13>
         <PDBx:U22>0.7495</PDBx:U22>
         <PDBx:U23>-0.0993</PDBx:U23>
         <PDBx:U33>0.6182</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1630">
         <PDBx:U11>0.3908</PDBx:U11>
         <PDBx:U12>-0.1804</PDBx:U12>
         <PDBx:U13>0.0633</PDBx:U13>
         <PDBx:U22>0.3513</PDBx:U22>
         <PDBx:U23>-0.0772</PDBx:U23>
         <PDBx:U33>0.2909</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1631">
         <PDBx:U11>0.4257</PDBx:U11>
         <PDBx:U12>-0.1896</PDBx:U12>
         <PDBx:U13>0.0730</PDBx:U13>
         <PDBx:U22>0.3918</PDBx:U22>
         <PDBx:U23>-0.0805</PDBx:U23>
         <PDBx:U33>0.3322</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U12>-0.2408</PDBx:U12>
         <PDBx:U13>0.0795</PDBx:U13>
         <PDBx:U22>0.5976</PDBx:U22>
         <PDBx:U23>-0.1174</PDBx:U23>
         <PDBx:U33>0.4549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0757</PDBx:U13>
         <PDBx:U22>0.6487</PDBx:U22>
         <PDBx:U23>-0.1275</PDBx:U23>
         <PDBx:U33>0.4618</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1665">
         <PDBx:U11>0.3829</PDBx:U11>
         <PDBx:U12>-0.2246</PDBx:U12>
         <PDBx:U13>0.0823</PDBx:U13>
         <PDBx:U22>0.5177</PDBx:U22>
         <PDBx:U23>-0.1066</PDBx:U23>
         <PDBx:U33>0.3905</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1666">
         <PDBx:U11>0.4362</PDBx:U11>
         <PDBx:U12>-0.2247</PDBx:U12>
         <PDBx:U13>0.0966</PDBx:U13>
         <PDBx:U22>0.5112</PDBx:U22>
         <PDBx:U23>-0.0999</PDBx:U23>
         <PDBx:U33>0.4114</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1667">
         <PDBx:U11>0.4746</PDBx:U11>
         <PDBx:U12>-0.2093</PDBx:U12>
         <PDBx:U13>0.0971</PDBx:U13>
         <PDBx:U22>0.5295</PDBx:U22>
         <PDBx:U23>-0.0901</PDBx:U23>
         <PDBx:U33>0.4383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1668">
         <PDBx:U11>0.4771</PDBx:U11>
         <PDBx:U12>-0.2410</PDBx:U12>
         <PDBx:U13>0.1134</PDBx:U13>
         <PDBx:U22>0.5525</PDBx:U22>
         <PDBx:U23>-0.1042</PDBx:U23>
         <PDBx:U33>0.4557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1669">
         <PDBx:U11>0.5649</PDBx:U11>
         <PDBx:U12>0.0440</PDBx:U12>
         <PDBx:U13>0.1044</PDBx:U13>
         <PDBx:U22>0.6806</PDBx:U22>
         <PDBx:U23>-0.0541</PDBx:U23>
         <PDBx:U33>0.4011</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1670">
         <PDBx:U11>0.5187</PDBx:U11>
         <PDBx:U12>0.0345</PDBx:U12>
         <PDBx:U13>0.1156</PDBx:U13>
         <PDBx:U22>0.7292</PDBx:U22>
         <PDBx:U23>-0.0188</PDBx:U23>
         <PDBx:U33>0.3916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1671">
         <PDBx:U11>0.5211</PDBx:U11>
         <PDBx:U12>0.0086</PDBx:U12>
         <PDBx:U13>0.1188</PDBx:U13>
         <PDBx:U22>0.8350</PDBx:U22>
         <PDBx:U23>-0.0427</PDBx:U23>
         <PDBx:U33>0.4009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1672">
         <PDBx:U11>0.4770</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>0.1206</PDBx:U13>
         <PDBx:U22>0.9038</PDBx:U22>
         <PDBx:U23>-0.0094</PDBx:U23>
         <PDBx:U33>0.3951</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1673">
         <PDBx:U11>0.5068</PDBx:U11>
         <PDBx:U12>0.0472</PDBx:U12>
         <PDBx:U13>0.1077</PDBx:U13>
         <PDBx:U22>0.7874</PDBx:U22>
         <PDBx:U23>0.0344</PDBx:U23>
         <PDBx:U33>0.4228</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1674">
         <PDBx:U11>0.5134</PDBx:U11>
         <PDBx:U12>0.0490</PDBx:U12>
         <PDBx:U13>0.0905</PDBx:U13>
         <PDBx:U22>0.8834</PDBx:U22>
         <PDBx:U23>0.0322</PDBx:U23>
         <PDBx:U33>0.4423</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1675">
         <PDBx:U11>0.5282</PDBx:U11>
         <PDBx:U12>0.0664</PDBx:U12>
         <PDBx:U13>0.0763</PDBx:U13>
         <PDBx:U22>0.8620</PDBx:U22>
         <PDBx:U23>0.0498</PDBx:U23>
         <PDBx:U33>0.4556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1676">
         <PDBx:U11>0.5099</PDBx:U11>
         <PDBx:U12>0.0285</PDBx:U12>
         <PDBx:U13>0.0895</PDBx:U13>
         <PDBx:U22>1.0062</PDBx:U22>
         <PDBx:U23>0.0137</PDBx:U23>
         <PDBx:U33>0.4502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1677">
         <PDBx:U11>0.4789</PDBx:U11>
         <PDBx:U12>0.0672</PDBx:U12>
         <PDBx:U13>0.0629</PDBx:U13>
         <PDBx:U22>0.9045</PDBx:U22>
         <PDBx:U23>0.0498</PDBx:U23>
         <PDBx:U33>0.4222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1678">
         <PDBx:U11>0.5213</PDBx:U11>
         <PDBx:U12>0.0272</PDBx:U12>
         <PDBx:U13>0.0790</PDBx:U13>
         <PDBx:U22>1.1070</PDBx:U22>
         <PDBx:U23>0.0085</PDBx:U23>
         <PDBx:U33>0.4714</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1679">
         <PDBx:U11>0.5045</PDBx:U11>
         <PDBx:U12>0.0486</PDBx:U12>
         <PDBx:U13>0.0664</PDBx:U13>
         <PDBx:U22>1.0573</PDBx:U22>
         <PDBx:U23>0.0273</PDBx:U23>
         <PDBx:U33>0.4596</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1680">
         <PDBx:U11>0.4613</PDBx:U11>
         <PDBx:U12>0.0465</PDBx:U12>
         <PDBx:U13>0.0581</PDBx:U13>
         <PDBx:U22>1.1123</PDBx:U22>
         <PDBx:U23>0.0236</PDBx:U23>
         <PDBx:U33>0.4298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1681">
         <PDBx:U11>0.6154</PDBx:U11>
         <PDBx:U12>-0.0016</PDBx:U12>
         <PDBx:U13>0.1176</PDBx:U13>
         <PDBx:U22>0.8869</PDBx:U22>
         <PDBx:U23>-0.0985</PDBx:U23>
         <PDBx:U33>0.4585</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1682">
         <PDBx:U11>0.6772</PDBx:U11>
         <PDBx:U12>-0.0332</PDBx:U12>
         <PDBx:U13>0.1222</PDBx:U13>
         <PDBx:U22>1.0159</PDBx:U22>
         <PDBx:U23>-0.1296</PDBx:U23>
         <PDBx:U33>0.5104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1683">
         <PDBx:U11>0.8211</PDBx:U11>
         <PDBx:U12>-0.0478</PDBx:U12>
         <PDBx:U13>0.1308</PDBx:U13>
         <PDBx:U22>1.0801</PDBx:U22>
         <PDBx:U23>-0.1357</PDBx:U23>
         <PDBx:U33>0.6309</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1684">
         <PDBx:U11>0.8793</PDBx:U11>
         <PDBx:U12>-0.0702</PDBx:U12>
         <PDBx:U13>0.1384</PDBx:U13>
         <PDBx:U22>1.2026</PDBx:U22>
         <PDBx:U23>-0.1143</PDBx:U23>
         <PDBx:U33>0.7050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1685">
         <PDBx:U11>0.6560</PDBx:U11>
         <PDBx:U12>-0.0361</PDBx:U12>
         <PDBx:U13>0.1185</PDBx:U13>
         <PDBx:U22>0.9839</PDBx:U22>
         <PDBx:U23>-0.1931</PDBx:U23>
         <PDBx:U33>0.4636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1686">
         <PDBx:U11>0.6841</PDBx:U11>
         <PDBx:U12>-0.0317</PDBx:U12>
         <PDBx:U13>0.1163</PDBx:U13>
         <PDBx:U22>0.8757</PDBx:U22>
         <PDBx:U23>-0.2298</PDBx:U23>
         <PDBx:U33>0.4587</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1687">
         <PDBx:U11>0.8794</PDBx:U11>
         <PDBx:U12>-0.0375</PDBx:U12>
         <PDBx:U13>0.1276</PDBx:U13>
         <PDBx:U22>1.0030</PDBx:U22>
         <PDBx:U23>-0.1600</PDBx:U23>
         <PDBx:U33>0.6546</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1688">
         <PDBx:U11>0.9123</PDBx:U11>
         <PDBx:U12>-0.0562</PDBx:U12>
         <PDBx:U13>0.1333</PDBx:U13>
         <PDBx:U22>0.9507</PDBx:U22>
         <PDBx:U23>-0.1703</PDBx:U23>
         <PDBx:U33>0.6561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1689">
         <PDBx:U11>0.8518</PDBx:U11>
         <PDBx:U12>-0.0478</PDBx:U12>
         <PDBx:U13>0.1476</PDBx:U13>
         <PDBx:U22>0.8435</PDBx:U22>
         <PDBx:U23>-0.1279</PDBx:U23>
         <PDBx:U33>0.6016</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1690">
         <PDBx:U11>0.8349</PDBx:U11>
         <PDBx:U12>-0.0480</PDBx:U12>
         <PDBx:U13>0.1475</PDBx:U13>
         <PDBx:U22>0.7091</PDBx:U22>
         <PDBx:U23>-0.1341</PDBx:U23>
         <PDBx:U33>0.5486</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1691">
         <PDBx:U11>0.9951</PDBx:U11>
         <PDBx:U12>-0.0552</PDBx:U12>
         <PDBx:U13>0.1193</PDBx:U13>
         <PDBx:U22>0.9107</PDBx:U22>
         <PDBx:U23>-0.2136</PDBx:U23>
         <PDBx:U33>0.6995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1692">
         <PDBx:U11>0.9864</PDBx:U11>
         <PDBx:U12>-0.0244</PDBx:U12>
         <PDBx:U13>0.1074</PDBx:U13>
         <PDBx:U22>0.8385</PDBx:U22>
         <PDBx:U23>-0.2058</PDBx:U23>
         <PDBx:U33>0.6943</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1693">
         <PDBx:U11>1.0426</PDBx:U11>
         <PDBx:U12>-0.0131</PDBx:U12>
         <PDBx:U13>0.0888</PDBx:U13>
         <PDBx:U22>0.8348</PDBx:U22>
         <PDBx:U23>-0.2584</PDBx:U23>
         <PDBx:U33>0.7467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1694">
         <PDBx:U11>0.8970</PDBx:U11>
         <PDBx:U12>-0.0406</PDBx:U12>
         <PDBx:U13>0.0777</PDBx:U13>
         <PDBx:U22>0.5659</PDBx:U22>
         <PDBx:U23>-0.2779</PDBx:U23>
         <PDBx:U33>0.5620</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1695">
         <PDBx:U11>0.8303</PDBx:U11>
         <PDBx:U12>-0.0428</PDBx:U12>
         <PDBx:U13>0.1608</PDBx:U13>
         <PDBx:U22>0.9134</PDBx:U22>
         <PDBx:U23>-0.0848</PDBx:U23>
         <PDBx:U33>0.6271</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1696">
         <PDBx:U11>0.8379</PDBx:U11>
         <PDBx:U12>-0.0327</PDBx:U12>
         <PDBx:U13>0.1823</PDBx:U13>
         <PDBx:U22>0.8798</PDBx:U22>
         <PDBx:U23>-0.0500</PDBx:U23>
         <PDBx:U33>0.6488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1697">
         <PDBx:U11>0.9499</PDBx:U11>
         <PDBx:U12>-0.0577</PDBx:U12>
         <PDBx:U13>0.1983</PDBx:U13>
         <PDBx:U22>0.9565</PDBx:U22>
         <PDBx:U23>-0.0598</PDBx:U23>
         <PDBx:U33>0.7400</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1698">
         <PDBx:U11>0.9987</PDBx:U11>
         <PDBx:U12>-0.0783</PDBx:U12>
         <PDBx:U13>0.1881</PDBx:U13>
         <PDBx:U22>0.9344</PDBx:U22>
         <PDBx:U23>-0.0962</PDBx:U23>
         <PDBx:U33>0.7379</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1699">
         <PDBx:U11>0.7936</PDBx:U11>
         <PDBx:U12>-0.0183</PDBx:U12>
         <PDBx:U13>0.1922</PDBx:U13>
         <PDBx:U22>0.9443</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.6762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1700">
         <PDBx:U11>0.7498</PDBx:U11>
         <PDBx:U12>0.0011</PDBx:U12>
         <PDBx:U13>0.1748</PDBx:U13>
         <PDBx:U22>0.9446</PDBx:U22>
         <PDBx:U23>0.0186</PDBx:U23>
         <PDBx:U33>0.6543</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1701">
         <PDBx:U11>0.7588</PDBx:U11>
         <PDBx:U12>0.0188</PDBx:U12>
         <PDBx:U13>0.1839</PDBx:U13>
         <PDBx:U22>1.0175</PDBx:U22>
         <PDBx:U23>0.0763</PDBx:U23>
         <PDBx:U33>0.7320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1702">
         <PDBx:U11>0.7788</PDBx:U11>
         <PDBx:U12>0.0318</PDBx:U12>
         <PDBx:U13>0.1620</PDBx:U13>
         <PDBx:U22>1.0851</PDBx:U22>
         <PDBx:U23>0.0960</PDBx:U23>
         <PDBx:U33>0.7695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1703">
         <PDBx:U11>0.7969</PDBx:U11>
         <PDBx:U12>0.0557</PDBx:U12>
         <PDBx:U13>0.1688</PDBx:U13>
         <PDBx:U22>1.0875</PDBx:U22>
         <PDBx:U23>0.1452</PDBx:U23>
         <PDBx:U33>0.8324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1704">
         <PDBx:U11>1.0737</PDBx:U11>
         <PDBx:U12>-0.1713</PDBx:U12>
         <PDBx:U13>0.1841</PDBx:U13>
         <PDBx:U22>1.2461</PDBx:U22>
         <PDBx:U23>-0.1070</PDBx:U23>
         <PDBx:U33>0.8378</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1705">
         <PDBx:U11>1.1113</PDBx:U11>
         <PDBx:U12>-0.1423</PDBx:U12>
         <PDBx:U13>0.1968</PDBx:U13>
         <PDBx:U22>1.1765</PDBx:U22>
         <PDBx:U23>-0.0992</PDBx:U23>
         <PDBx:U33>0.8643</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1706">
         <PDBx:U11>1.1839</PDBx:U11>
         <PDBx:U12>-0.1605</PDBx:U12>
         <PDBx:U13>0.1894</PDBx:U13>
         <PDBx:U22>1.1137</PDBx:U22>
         <PDBx:U23>-0.1337</PDBx:U23>
         <PDBx:U33>0.8696</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1707">
         <PDBx:U11>1.2158</PDBx:U11>
         <PDBx:U12>-0.1869</PDBx:U12>
         <PDBx:U13>0.2005</PDBx:U13>
         <PDBx:U22>1.1256</PDBx:U22>
         <PDBx:U23>-0.1300</PDBx:U23>
         <PDBx:U33>0.8853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1708">
         <PDBx:U11>1.0952</PDBx:U11>
         <PDBx:U12>-0.1292</PDBx:U12>
         <PDBx:U13>0.2277</PDBx:U13>
         <PDBx:U22>1.2006</PDBx:U22>
         <PDBx:U23>-0.0519</PDBx:U23>
         <PDBx:U33>0.9005</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>532</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>232</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1709">
         <PDBx:U11>1.1689</PDBx:U11>
         <PDBx:U12>-0.1481</PDBx:U12>
         <PDBx:U13>0.1691</PDBx:U13>
         <PDBx:U22>1.0116</PDBx:U22>
         <PDBx:U23>-0.1625</PDBx:U23>
         <PDBx:U33>0.8208</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1710">
         <PDBx:U11>1.1753</PDBx:U11>
         <PDBx:U12>-0.1668</PDBx:U12>
         <PDBx:U13>0.1540</PDBx:U13>
         <PDBx:U22>0.8885</PDBx:U22>
         <PDBx:U23>-0.1891</PDBx:U23>
         <PDBx:U33>0.7703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1711">
         <PDBx:U11>1.1915</PDBx:U11>
         <PDBx:U12>-0.1764</PDBx:U12>
         <PDBx:U13>0.1724</PDBx:U13>
         <PDBx:U22>0.8340</PDBx:U22>
         <PDBx:U23>-0.1677</PDBx:U23>
         <PDBx:U33>0.7610</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1712">
         <PDBx:U11>1.2265</PDBx:U11>
         <PDBx:U12>-0.2082</PDBx:U12>
         <PDBx:U13>0.1830</PDBx:U13>
         <PDBx:U22>0.8704</PDBx:U22>
         <PDBx:U23>-0.1648</PDBx:U23>
         <PDBx:U33>0.7805</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1713">
         <PDBx:U11>1.1569</PDBx:U11>
         <PDBx:U12>-0.1448</PDBx:U12>
         <PDBx:U13>0.1295</PDBx:U13>
         <PDBx:U22>0.7934</PDBx:U22>
         <PDBx:U23>-0.2115</PDBx:U23>
         <PDBx:U33>0.7380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1714">
         <PDBx:U11>1.1940</PDBx:U11>
         <PDBx:U12>-0.1566</PDBx:U12>
         <PDBx:U13>0.1031</PDBx:U13>
         <PDBx:U22>0.7296</PDBx:U22>
         <PDBx:U23>-0.2119</PDBx:U23>
         <PDBx:U33>0.7556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1715">
         <PDBx:U11>1.1499</PDBx:U11>
         <PDBx:U12>-0.1376</PDBx:U12>
         <PDBx:U13>0.1175</PDBx:U13>
         <PDBx:U22>0.8526</PDBx:U22>
         <PDBx:U23>-0.2426</PDBx:U23>
         <PDBx:U33>0.7521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1716">
         <PDBx:U11>1.1806</PDBx:U11>
         <PDBx:U12>-0.1534</PDBx:U12>
         <PDBx:U13>0.1772</PDBx:U13>
         <PDBx:U22>0.7634</PDBx:U22>
         <PDBx:U23>-0.1538</PDBx:U23>
         <PDBx:U33>0.7419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1717">
         <PDBx:U11>1.2152</PDBx:U11>
         <PDBx:U12>-0.1655</PDBx:U12>
         <PDBx:U13>0.1996</PDBx:U13>
         <PDBx:U22>0.7283</PDBx:U22>
         <PDBx:U23>-0.1387</PDBx:U23>
         <PDBx:U33>0.7438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1718">
         <PDBx:U11>1.2186</PDBx:U11>
         <PDBx:U12>-0.1369</PDBx:U12>
         <PDBx:U13>0.2353</PDBx:U13>
         <PDBx:U22>0.7879</PDBx:U22>
         <PDBx:U23>-0.1096</PDBx:U23>
         <PDBx:U33>0.7920</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1719">
         <PDBx:U11>1.1546</PDBx:U11>
         <PDBx:U12>-0.1075</PDBx:U12>
         <PDBx:U13>0.2338</PDBx:U13>
         <PDBx:U22>0.8050</PDBx:U22>
         <PDBx:U23>-0.0958</PDBx:U23>
         <PDBx:U33>0.7814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1720">
         <PDBx:U11>1.2077</PDBx:U11>
         <PDBx:U12>-0.1641</PDBx:U12>
         <PDBx:U13>0.1712</PDBx:U13>
         <PDBx:U22>0.6281</PDBx:U22>
         <PDBx:U23>-0.1307</PDBx:U23>
         <PDBx:U33>0.7063</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1721">
         <PDBx:U11>1.2359</PDBx:U11>
         <PDBx:U12>-0.1685</PDBx:U12>
         <PDBx:U13>0.1259</PDBx:U13>
         <PDBx:U22>0.6526</PDBx:U22>
         <PDBx:U23>-0.1384</PDBx:U23>
         <PDBx:U33>0.7464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1722">
         <PDBx:U11>1.0931</PDBx:U11>
         <PDBx:U12>-0.1292</PDBx:U12>
         <PDBx:U13>0.1668</PDBx:U13>
         <PDBx:U22>0.5143</PDBx:U22>
         <PDBx:U23>-0.1173</PDBx:U23>
         <PDBx:U33>0.6115</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1723">
         <PDBx:U11>1.2989</PDBx:U11>
         <PDBx:U12>-0.1473</PDBx:U12>
         <PDBx:U13>0.2686</PDBx:U13>
         <PDBx:U22>0.8252</PDBx:U22>
         <PDBx:U23>-0.1005</PDBx:U23>
         <PDBx:U33>0.8521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1724">
         <PDBx:U11>1.2980</PDBx:U11>
         <PDBx:U12>-0.1172</PDBx:U12>
         <PDBx:U13>0.3066</PDBx:U13>
         <PDBx:U22>0.8599</PDBx:U22>
         <PDBx:U23>-0.0764</PDBx:U23>
         <PDBx:U33>0.8979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1725">
         <PDBx:U11>1.2920</PDBx:U11>
         <PDBx:U12>-0.0954</PDBx:U12>
         <PDBx:U13>0.2975</PDBx:U13>
         <PDBx:U22>0.7854</PDBx:U22>
         <PDBx:U23>-0.0715</PDBx:U23>
         <PDBx:U33>0.8724</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1726">
         <PDBx:U11>1.3671</PDBx:U11>
         <PDBx:U12>-0.1156</PDBx:U12>
         <PDBx:U13>0.2853</PDBx:U13>
         <PDBx:U22>0.7511</PDBx:U22>
         <PDBx:U23>-0.0836</PDBx:U23>
         <PDBx:U33>0.8765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1727">
         <PDBx:U11>1.3405</PDBx:U11>
         <PDBx:U12>-0.1407</PDBx:U12>
         <PDBx:U13>0.3483</PDBx:U13>
         <PDBx:U22>0.8636</PDBx:U22>
         <PDBx:U23>-0.0794</PDBx:U23>
         <PDBx:U33>0.9135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1728">
         <PDBx:U11>1.4049</PDBx:U11>
         <PDBx:U12>-0.1849</PDBx:U12>
         <PDBx:U13>0.3233</PDBx:U13>
         <PDBx:U22>0.8303</PDBx:U22>
         <PDBx:U23>-0.1020</PDBx:U23>
         <PDBx:U33>0.8905</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1729">
         <PDBx:U11>1.3538</PDBx:U11>
         <PDBx:U12>-0.1898</PDBx:U12>
         <PDBx:U13>0.2755</PDBx:U13>
         <PDBx:U22>0.8032</PDBx:U22>
         <PDBx:U23>-0.1128</PDBx:U23>
         <PDBx:U33>0.8436</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1730">
         <PDBx:U11>1.2023</PDBx:U11>
         <PDBx:U12>-0.0596</PDBx:U12>
         <PDBx:U13>0.2994</PDBx:U13>
         <PDBx:U22>0.7635</PDBx:U22>
         <PDBx:U23>-0.0490</PDBx:U23>
         <PDBx:U33>0.8451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1731">
         <PDBx:U11>1.1524</PDBx:U11>
         <PDBx:U12>-0.0403</PDBx:U12>
         <PDBx:U13>0.2898</PDBx:U13>
         <PDBx:U22>0.6590</PDBx:U22>
         <PDBx:U23>-0.0390</PDBx:U23>
         <PDBx:U33>0.7821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1732">
         <PDBx:U11>1.1512</PDBx:U11>
         <PDBx:U12>-0.0246</PDBx:U12>
         <PDBx:U13>0.3335</PDBx:U13>
         <PDBx:U22>0.6333</PDBx:U22>
         <PDBx:U23>-0.0233</PDBx:U23>
         <PDBx:U33>0.8010</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1733">
         <PDBx:U11>1.1257</PDBx:U11>
         <PDBx:U12>-0.0081</PDBx:U12>
         <PDBx:U13>0.3649</PDBx:U13>
         <PDBx:U22>0.6847</PDBx:U22>
         <PDBx:U23>-0.0069</PDBx:U23>
         <PDBx:U33>0.8453</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1734">
         <PDBx:U11>1.0484</PDBx:U11>
         <PDBx:U12>-0.0147</PDBx:U12>
         <PDBx:U13>0.2597</PDBx:U13>
         <PDBx:U22>0.6413</PDBx:U22>
         <PDBx:U23>-0.0238</PDBx:U23>
         <PDBx:U33>0.7297</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1735">
         <PDBx:U11>1.0389</PDBx:U11>
         <PDBx:U12>-0.0229</PDBx:U12>
         <PDBx:U13>0.2177</PDBx:U13>
         <PDBx:U22>0.6315</PDBx:U22>
         <PDBx:U23>-0.0451</PDBx:U23>
         <PDBx:U33>0.6958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1736">
         <PDBx:U11>1.0756</PDBx:U11>
         <PDBx:U12>-0.0514</PDBx:U12>
         <PDBx:U13>0.2123</PDBx:U13>
         <PDBx:U22>0.6634</PDBx:U22>
         <PDBx:U23>-0.0729</PDBx:U23>
         <PDBx:U33>0.7073</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1737">
         <PDBx:U11>0.9304</PDBx:U11>
         <PDBx:U12>-0.0008</PDBx:U12>
         <PDBx:U13>0.2000</PDBx:U13>
         <PDBx:U22>0.6363</PDBx:U22>
         <PDBx:U23>-0.0320</PDBx:U23>
         <PDBx:U33>0.6454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1738">
         <PDBx:U11>1.1653</PDBx:U11>
         <PDBx:U12>-0.0313</PDBx:U12>
         <PDBx:U13>0.3357</PDBx:U13>
         <PDBx:U22>0.5388</PDBx:U22>
         <PDBx:U23>-0.0280</PDBx:U23>
         <PDBx:U33>0.7563</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1739">
         <PDBx:U11>1.1756</PDBx:U11>
         <PDBx:U12>-0.0191</PDBx:U12>
         <PDBx:U13>0.3753</PDBx:U13>
         <PDBx:U22>0.5213</PDBx:U22>
         <PDBx:U23>-0.0193</PDBx:U23>
         <PDBx:U33>0.7803</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1740">
         <PDBx:U11>1.0575</PDBx:U11>
         <PDBx:U12>0.0237</PDBx:U12>
         <PDBx:U13>0.3816</PDBx:U13>
         <PDBx:U22>0.4702</PDBx:U22>
         <PDBx:U23>0.0130</PDBx:U23>
         <PDBx:U33>0.7525</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1741">
         <PDBx:U11>1.0359</PDBx:U11>
         <PDBx:U12>0.0367</PDBx:U12>
         <PDBx:U13>0.3428</PDBx:U13>
         <PDBx:U22>0.5228</PDBx:U22>
         <PDBx:U23>0.0309</PDBx:U23>
         <PDBx:U33>0.7665</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1742">
         <PDBx:U11>1.2327</PDBx:U11>
         <PDBx:U12>-0.0386</PDBx:U12>
         <PDBx:U13>0.3448</PDBx:U13>
         <PDBx:U22>0.5498</PDBx:U22>
         <PDBx:U23>-0.0246</PDBx:U23>
         <PDBx:U33>0.7780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1743">
         <PDBx:U11>1.1765</PDBx:U11>
         <PDBx:U12>-0.0257</PDBx:U12>
         <PDBx:U13>0.2977</PDBx:U13>
         <PDBx:U22>0.5134</PDBx:U22>
         <PDBx:U23>-0.0122</PDBx:U23>
         <PDBx:U33>0.7315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1744">
         <PDBx:U11>0.3317</PDBx:U11>
         <PDBx:U12>-0.1541</PDBx:U12>
         <PDBx:U13>0.1550</PDBx:U13>
         <PDBx:U22>0.8114</PDBx:U22>
         <PDBx:U23>-0.0356</PDBx:U23>
         <PDBx:U33>0.7075</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1745">
         <PDBx:U11>0.3902</PDBx:U11>
         <PDBx:U12>-0.1296</PDBx:U12>
         <PDBx:U13>0.1258</PDBx:U13>
         <PDBx:U22>0.9293</PDBx:U22>
         <PDBx:U23>-0.0131</PDBx:U23>
         <PDBx:U33>0.7804</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1746">
         <PDBx:U11>0.3716</PDBx:U11>
         <PDBx:U12>-0.1115</PDBx:U12>
         <PDBx:U13>0.1128</PDBx:U13>
         <PDBx:U22>0.8455</PDBx:U22>
         <PDBx:U23>-0.0016</PDBx:U23>
         <PDBx:U33>0.7137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1747">
         <PDBx:U11>0.3493</PDBx:U11>
         <PDBx:U12>-0.1105</PDBx:U12>
         <PDBx:U13>0.0902</PDBx:U13>
         <PDBx:U22>0.8583</PDBx:U22>
         <PDBx:U23>0.0061</PDBx:U23>
         <PDBx:U33>0.6837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1748">
         <PDBx:U11>0.4524</PDBx:U11>
         <PDBx:U12>-0.0948</PDBx:U12>
         <PDBx:U13>0.1293</PDBx:U13>
         <PDBx:U22>1.0269</PDBx:U22>
         <PDBx:U23>0.0107</PDBx:U23>
         <PDBx:U33>0.8829</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1749">
         <PDBx:U11>0.5352</PDBx:U11>
         <PDBx:U12>-0.1112</PDBx:U12>
         <PDBx:U13>0.1366</PDBx:U13>
         <PDBx:U22>1.1985</PDBx:U22>
         <PDBx:U23>-0.0010</PDBx:U23>
         <PDBx:U33>1.0280</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1750">
         <PDBx:U11>0.5654</PDBx:U11>
         <PDBx:U12>-0.1384</PDBx:U12>
         <PDBx:U13>0.1208</PDBx:U13>
         <PDBx:U22>1.2647</PDBx:U22>
         <PDBx:U23>-0.0190</PDBx:U23>
         <PDBx:U33>1.0620</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1751">
         <PDBx:U11>0.5778</PDBx:U11>
         <PDBx:U12>-0.0923</PDBx:U12>
         <PDBx:U13>0.1556</PDBx:U13>
         <PDBx:U22>1.2486</PDBx:U22>
         <PDBx:U23>0.0070</PDBx:U23>
         <PDBx:U33>1.1046</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1752">
         <PDBx:U11>0.3674</PDBx:U11>
         <PDBx:U12>-0.0979</PDBx:U12>
         <PDBx:U13>0.1278</PDBx:U13>
         <PDBx:U22>0.7469</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.6764</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1753">
         <PDBx:U11>0.3294</PDBx:U11>
         <PDBx:U12>-0.0822</PDBx:U12>
         <PDBx:U13>0.1181</PDBx:U13>
         <PDBx:U22>0.6454</PDBx:U22>
         <PDBx:U23>0.0036</PDBx:U23>
         <PDBx:U33>0.6007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1754">
         <PDBx:U11>0.3143</PDBx:U11>
         <PDBx:U12>-0.1125</PDBx:U12>
         <PDBx:U13>0.1101</PDBx:U13>
         <PDBx:U22>0.6214</PDBx:U22>
         <PDBx:U23>-0.0185</PDBx:U23>
         <PDBx:U33>0.5637</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1755">
         <PDBx:U11>0.2974</PDBx:U11>
         <PDBx:U12>-0.1100</PDBx:U12>
         <PDBx:U13>0.0951</PDBx:U13>
         <PDBx:U22>0.6143</PDBx:U22>
         <PDBx:U23>-0.0134</PDBx:U23>
         <PDBx:U33>0.5350</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1756">
         <PDBx:U11>0.3675</PDBx:U11>
         <PDBx:U12>-0.0628</PDBx:U12>
         <PDBx:U13>0.1332</PDBx:U13>
         <PDBx:U22>0.5904</PDBx:U22>
         <PDBx:U23>0.0031</PDBx:U23>
         <PDBx:U33>0.6107</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1757">
         <PDBx:U11>0.4034</PDBx:U11>
         <PDBx:U12>-0.0506</PDBx:U12>
         <PDBx:U13>0.1239</PDBx:U13>
         <PDBx:U22>0.5588</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.6137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1758">
         <PDBx:U11>0.3827</PDBx:U11>
         <PDBx:U12>-0.0286</PDBx:U12>
         <PDBx:U13>0.1106</PDBx:U13>
         <PDBx:U22>0.5617</PDBx:U22>
         <PDBx:U23>0.0210</PDBx:U23>
         <PDBx:U33>0.6017</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1759">
         <PDBx:U11>0.5105</PDBx:U11>
         <PDBx:U12>-0.0320</PDBx:U12>
         <PDBx:U13>0.1347</PDBx:U13>
         <PDBx:U22>0.5814</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.6926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1760">
         <PDBx:U11>0.3364</PDBx:U11>
         <PDBx:U12>-0.1413</PDBx:U12>
         <PDBx:U13>0.1237</PDBx:U13>
         <PDBx:U22>0.6207</PDBx:U22>
         <PDBx:U23>-0.0433</PDBx:U23>
         <PDBx:U33>0.5798</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1761">
         <PDBx:U11>0.3208</PDBx:U11>
         <PDBx:U12>-0.1712</PDBx:U12>
         <PDBx:U13>0.1207</PDBx:U13>
         <PDBx:U22>0.5918</PDBx:U22>
         <PDBx:U23>-0.0683</PDBx:U23>
         <PDBx:U33>0.5476</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1762">
         <PDBx:U11>0.3192</PDBx:U11>
         <PDBx:U12>-0.1912</PDBx:U12>
         <PDBx:U13>0.1039</PDBx:U13>
         <PDBx:U22>0.6762</PDBx:U22>
         <PDBx:U23>-0.0717</PDBx:U23>
         <PDBx:U33>0.5592</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1763">
         <PDBx:U11>0.3258</PDBx:U11>
         <PDBx:U12>-0.2026</PDBx:U12>
         <PDBx:U13>0.0957</PDBx:U13>
         <PDBx:U22>0.6760</PDBx:U22>
         <PDBx:U23>-0.0818</PDBx:U23>
         <PDBx:U33>0.5460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1764">
         <PDBx:U11>0.4053</PDBx:U11>
         <PDBx:U12>-0.1997</PDBx:U12>
         <PDBx:U13>0.1416</PDBx:U13>
         <PDBx:U22>0.6441</PDBx:U22>
         <PDBx:U23>-0.0926</PDBx:U23>
         <PDBx:U33>0.6296</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1765">
         <PDBx:U11>0.4934</PDBx:U11>
         <PDBx:U12>-0.2167</PDBx:U12>
         <PDBx:U13>0.1386</PDBx:U13>
         <PDBx:U22>0.6854</PDBx:U22>
         <PDBx:U23>-0.1166</PDBx:U23>
         <PDBx:U33>0.6895</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1766">
         <PDBx:U11>0.4521</PDBx:U11>
         <PDBx:U12>-0.2017</PDBx:U12>
         <PDBx:U13>0.1373</PDBx:U13>
         <PDBx:U22>0.5751</PDBx:U22>
         <PDBx:U23>-0.1181</PDBx:U23>
         <PDBx:U33>0.6304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1767">
         <PDBx:U11>0.5875</PDBx:U11>
         <PDBx:U12>-0.2311</PDBx:U12>
         <PDBx:U13>0.1553</PDBx:U13>
         <PDBx:U22>0.7400</PDBx:U22>
         <PDBx:U23>-0.1325</PDBx:U23>
         <PDBx:U33>0.7716</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1768">
         <PDBx:U11>0.3355</PDBx:U11>
         <PDBx:U12>-0.1951</PDBx:U12>
         <PDBx:U13>0.0987</PDBx:U13>
         <PDBx:U22>0.7749</PDBx:U22>
         <PDBx:U23>-0.0643</PDBx:U23>
         <PDBx:U33>0.6086</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1769">
         <PDBx:U11>0.3645</PDBx:U11>
         <PDBx:U12>-0.2081</PDBx:U12>
         <PDBx:U13>0.0765</PDBx:U13>
         <PDBx:U22>0.8857</PDBx:U22>
         <PDBx:U23>-0.0650</PDBx:U23>
         <PDBx:U33>0.6430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1770">
         <PDBx:U11>0.3406</PDBx:U11>
         <PDBx:U12>-0.1826</PDBx:U12>
         <PDBx:U13>0.0577</PDBx:U13>
         <PDBx:U22>0.8791</PDBx:U22>
         <PDBx:U23>-0.0373</PDBx:U23>
         <PDBx:U33>0.6039</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1771">
         <PDBx:U11>0.3306</PDBx:U11>
         <PDBx:U12>-0.1974</PDBx:U12>
         <PDBx:U13>0.0441</PDBx:U13>
         <PDBx:U22>0.8961</PDBx:U22>
         <PDBx:U23>-0.0421</PDBx:U23>
         <PDBx:U33>0.5713</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1772">
         <PDBx:U11>0.3231</PDBx:U11>
         <PDBx:U12>-0.2095</PDBx:U12>
         <PDBx:U13>0.0707</PDBx:U13>
         <PDBx:U22>0.9168</PDBx:U22>
         <PDBx:U23>-0.0634</PDBx:U23>
         <PDBx:U33>0.6398</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1773">
         <PDBx:U11>0.3539</PDBx:U11>
         <PDBx:U12>-0.2381</PDBx:U12>
         <PDBx:U13>0.0813</PDBx:U13>
         <PDBx:U22>0.9332</PDBx:U22>
         <PDBx:U23>-0.0936</PDBx:U23>
         <PDBx:U33>0.6698</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1774">
         <PDBx:U11>0.3663</PDBx:U11>
         <PDBx:U12>-0.2405</PDBx:U12>
         <PDBx:U13>0.0741</PDBx:U13>
         <PDBx:U22>1.0267</PDBx:U22>
         <PDBx:U23>-0.0940</PDBx:U23>
         <PDBx:U33>0.7269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1775">
         <PDBx:U11>0.3774</PDBx:U11>
         <PDBx:U12>-0.2628</PDBx:U12>
         <PDBx:U13>0.0739</PDBx:U13>
         <PDBx:U22>0.9432</PDBx:U22>
         <PDBx:U23>-0.1175</PDBx:U23>
         <PDBx:U33>0.6552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1776">
         <PDBx:U11>0.3246</PDBx:U11>
         <PDBx:U12>-0.1427</PDBx:U12>
         <PDBx:U13>0.0590</PDBx:U13>
         <PDBx:U22>0.8364</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.5938</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1777">
         <PDBx:U11>0.3659</PDBx:U11>
         <PDBx:U12>-0.1134</PDBx:U12>
         <PDBx:U13>0.0455</PDBx:U13>
         <PDBx:U22>0.8743</PDBx:U22>
         <PDBx:U23>0.0217</PDBx:U23>
         <PDBx:U33>0.6171</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1778">
         <PDBx:U11>0.3886</PDBx:U11>
         <PDBx:U12>-0.1198</PDBx:U12>
         <PDBx:U13>0.0505</PDBx:U13>
         <PDBx:U22>0.8273</PDBx:U22>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0646</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0546</PDBx:U13>
         <PDBx:U22>0.9837</PDBx:U22>
         <PDBx:U23>0.0901</PDBx:U23>
         <PDBx:U33>0.7806</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0679</PDBx:U13>
         <PDBx:U22>0.8768</PDBx:U22>
         <PDBx:U23>0.0931</PDBx:U23>
         <PDBx:U33>0.7335</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U13>0.0492</PDBx:U13>
         <PDBx:U22>1.0593</PDBx:U22>
         <PDBx:U23>0.1047</PDBx:U23>
         <PDBx:U33>0.8341</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3457</PDBx:U11>
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         <PDBx:U13>0.0663</PDBx:U13>
         <PDBx:U22>0.7150</PDBx:U22>
         <PDBx:U23>-0.0113</PDBx:U23>
         <PDBx:U33>0.5504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1786">
         <PDBx:U11>0.3340</PDBx:U11>
         <PDBx:U12>-0.1372</PDBx:U12>
         <PDBx:U13>0.0713</PDBx:U13>
         <PDBx:U22>0.6428</PDBx:U22>
         <PDBx:U23>-0.0279</PDBx:U23>
         <PDBx:U33>0.5123</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.3146</PDBx:U11>
         <PDBx:U12>-0.1752</PDBx:U12>
         <PDBx:U13>0.0676</PDBx:U13>
         <PDBx:U22>0.6594</PDBx:U22>
         <PDBx:U23>-0.0515</PDBx:U23>
         <PDBx:U33>0.4789</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1788">
         <PDBx:U11>0.3253</PDBx:U11>
         <PDBx:U12>-0.1811</PDBx:U12>
         <PDBx:U13>0.0671</PDBx:U13>
         <PDBx:U22>0.6561</PDBx:U22>
         <PDBx:U23>-0.0552</PDBx:U23>
         <PDBx:U33>0.4668</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1789">
         <PDBx:U11>0.3679</PDBx:U11>
         <PDBx:U12>-0.1352</PDBx:U12>
         <PDBx:U13>0.0847</PDBx:U13>
         <PDBx:U22>0.5995</PDBx:U22>
         <PDBx:U23>-0.0470</PDBx:U23>
         <PDBx:U33>0.5450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1790">
         <PDBx:U11>0.4331</PDBx:U11>
         <PDBx:U12>-0.1008</PDBx:U12>
         <PDBx:U13>0.0896</PDBx:U13>
         <PDBx:U22>0.6257</PDBx:U22>
         <PDBx:U23>-0.0285</PDBx:U23>
         <PDBx:U33>0.6167</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.5577</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:U22>0.4349</PDBx:U22>
         <PDBx:U23>-0.0288</PDBx:U23>
         <PDBx:U33>0.4926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.3179</PDBx:U11>
         <PDBx:U12>-0.2030</PDBx:U12>
         <PDBx:U13>0.0679</PDBx:U13>
         <PDBx:U22>0.7084</PDBx:U22>
         <PDBx:U23>-0.0699</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.4325</PDBx:U11>
         <PDBx:U12>-0.2412</PDBx:U12>
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         <PDBx:U22>0.8597</PDBx:U22>
         <PDBx:U23>-0.0966</PDBx:U23>
         <PDBx:U33>0.5978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1795">
         <PDBx:U11>0.4433</PDBx:U11>
         <PDBx:U12>-0.2433</PDBx:U12>
         <PDBx:U13>0.0454</PDBx:U13>
         <PDBx:U22>0.9465</PDBx:U22>
         <PDBx:U23>-0.0795</PDBx:U23>
         <PDBx:U33>0.5934</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1796">
         <PDBx:U11>0.4118</PDBx:U11>
         <PDBx:U12>-0.2615</PDBx:U12>
         <PDBx:U13>0.0441</PDBx:U13>
         <PDBx:U22>0.9174</PDBx:U22>
         <PDBx:U23>-0.0906</PDBx:U23>
         <PDBx:U33>0.5304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1797">
         <PDBx:U11>0.4314</PDBx:U11>
         <PDBx:U12>-0.2545</PDBx:U12>
         <PDBx:U13>0.0688</PDBx:U13>
         <PDBx:U22>0.8587</PDBx:U22>
         <PDBx:U23>-0.1169</PDBx:U23>
         <PDBx:U33>0.6022</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1798">
         <PDBx:U11>0.4253</PDBx:U11>
         <PDBx:U12>-0.2538</PDBx:U12>
         <PDBx:U13>0.0867</PDBx:U13>
         <PDBx:U22>0.7654</PDBx:U22>
         <PDBx:U23>-0.1363</PDBx:U23>
         <PDBx:U33>0.5883</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1799">
         <PDBx:U11>0.4305</PDBx:U11>
         <PDBx:U12>-0.2687</PDBx:U12>
         <PDBx:U13>0.0938</PDBx:U13>
         <PDBx:U22>0.7822</PDBx:U22>
         <PDBx:U23>-0.1514</PDBx:U23>
         <PDBx:U33>0.6017</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1800">
         <PDBx:U11>0.4058</PDBx:U11>
         <PDBx:U12>-0.2584</PDBx:U12>
         <PDBx:U13>0.0920</PDBx:U13>
         <PDBx:U22>0.6929</PDBx:U22>
         <PDBx:U23>-0.1558</PDBx:U23>
         <PDBx:U33>0.5392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1801">
         <PDBx:U11>0.3532</PDBx:U11>
         <PDBx:U12>-0.2222</PDBx:U12>
         <PDBx:U13>0.0301</PDBx:U13>
         <PDBx:U22>0.9154</PDBx:U22>
         <PDBx:U23>-0.0519</PDBx:U23>
         <PDBx:U33>0.5230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1802">
         <PDBx:U11>0.3799</PDBx:U11>
         <PDBx:U12>-0.2161</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>1.0145</PDBx:U22>
         <PDBx:U23>-0.0296</PDBx:U23>
         <PDBx:U33>0.5328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1803">
         <PDBx:U11>0.3799</PDBx:U11>
         <PDBx:U12>-0.2163</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>1.0146</PDBx:U22>
         <PDBx:U23>-0.0298</PDBx:U23>
         <PDBx:U33>0.5328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1804">
         <PDBx:U11>0.3998</PDBx:U11>
         <PDBx:U12>-0.1985</PDBx:U12>
         <PDBx:U13>0.0067</PDBx:U13>
         <PDBx:U22>0.9902</PDBx:U22>
         <PDBx:U23>-0.0077</PDBx:U23>
         <PDBx:U33>0.5091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1805">
         <PDBx:U11>0.4366</PDBx:U11>
         <PDBx:U12>-0.2051</PDBx:U12>
         <PDBx:U13>-0.0074</PDBx:U13>
         <PDBx:U22>1.0664</PDBx:U22>
         <PDBx:U23>0.0021</PDBx:U23>
         <PDBx:U33>0.5097</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1806">
         <PDBx:U11>0.3746</PDBx:U11>
         <PDBx:U12>-0.1856</PDBx:U12>
         <PDBx:U13>-0.0096</PDBx:U13>
         <PDBx:U22>1.0684</PDBx:U22>
         <PDBx:U23>0.0008</PDBx:U23>
         <PDBx:U33>0.5643</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1807">
         <PDBx:U11>0.3744</PDBx:U11>
         <PDBx:U12>-0.1860</PDBx:U12>
         <PDBx:U13>-0.0094</PDBx:U13>
         <PDBx:U22>1.0683</PDBx:U22>
         <PDBx:U23>0.0003</PDBx:U23>
         <PDBx:U33>0.5645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1808">
         <PDBx:U11>0.4110</PDBx:U11>
         <PDBx:U12>-0.2109</PDBx:U12>
         <PDBx:U13>-0.0213</PDBx:U13>
         <PDBx:U22>1.1961</PDBx:U22>
         <PDBx:U23>-0.0198</PDBx:U23>
         <PDBx:U33>0.6375</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1809">
         <PDBx:U11>0.4274</PDBx:U11>
         <PDBx:U12>-0.1901</PDBx:U12>
         <PDBx:U13>-0.0399</PDBx:U13>
         <PDBx:U22>1.2229</PDBx:U22>
         <PDBx:U23>0.0110</PDBx:U23>
         <PDBx:U33>0.6131</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1810">
         <PDBx:U11>0.3756</PDBx:U11>
         <PDBx:U12>-0.2429</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>1.1372</PDBx:U22>
         <PDBx:U23>-0.0571</PDBx:U23>
         <PDBx:U33>0.6060</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1811">
         <PDBx:U11>0.4371</PDBx:U11>
         <PDBx:U12>-0.2137</PDBx:U12>
         <PDBx:U13>-0.0489</PDBx:U13>
         <PDBx:U22>1.2497</PDBx:U22>
         <PDBx:U23>0.0000</PDBx:U23>
         <PDBx:U33>0.5788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1812">
         <PDBx:U11>0.4231</PDBx:U11>
         <PDBx:U12>-0.1939</PDBx:U12>
         <PDBx:U13>-0.0456</PDBx:U13>
         <PDBx:U22>1.2894</PDBx:U22>
         <PDBx:U23>0.0014</PDBx:U23>
         <PDBx:U33>0.6701</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1813">
         <PDBx:U11>0.4394</PDBx:U11>
         <PDBx:U12>-0.1690</PDBx:U12>
         <PDBx:U13>-0.0554</PDBx:U13>
         <PDBx:U22>1.2991</PDBx:U22>
         <PDBx:U23>0.0293</PDBx:U23>
         <PDBx:U33>0.6656</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1814">
         <PDBx:U11>0.3812</PDBx:U11>
         <PDBx:U12>-0.1770</PDBx:U12>
         <PDBx:U13>0.0240</PDBx:U13>
         <PDBx:U22>0.8892</PDBx:U22>
         <PDBx:U23>-0.0010</PDBx:U23>
         <PDBx:U33>0.4922</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1815">
         <PDBx:U11>0.4451</PDBx:U11>
         <PDBx:U12>-0.1617</PDBx:U12>
         <PDBx:U13>0.0306</PDBx:U13>
         <PDBx:U22>0.9040</PDBx:U22>
         <PDBx:U23>0.0166</PDBx:U23>
         <PDBx:U33>0.5230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1816">
         <PDBx:U11>0.4229</PDBx:U11>
         <PDBx:U12>-0.1966</PDBx:U12>
         <PDBx:U13>0.0393</PDBx:U13>
         <PDBx:U22>0.8688</PDBx:U22>
         <PDBx:U23>-0.0111</PDBx:U23>
         <PDBx:U33>0.4642</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1817">
         <PDBx:U11>0.4561</PDBx:U11>
         <PDBx:U12>-0.1935</PDBx:U12>
         <PDBx:U13>0.0425</PDBx:U13>
         <PDBx:U22>0.8886</PDBx:U22>
         <PDBx:U23>0.0037</PDBx:U23>
         <PDBx:U33>0.4598</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1818">
         <PDBx:U11>0.4144</PDBx:U11>
         <PDBx:U12>-0.1362</PDBx:U12>
         <PDBx:U13>0.0473</PDBx:U13>
         <PDBx:U22>0.7920</PDBx:U22>
         <PDBx:U23>0.0202</PDBx:U23>
         <PDBx:U33>0.5097</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1819">
         <PDBx:U11>0.4108</PDBx:U11>
         <PDBx:U12>-0.2301</PDBx:U12>
         <PDBx:U13>0.0467</PDBx:U13>
         <PDBx:U22>0.8566</PDBx:U22>
         <PDBx:U23>-0.0516</PDBx:U23>
         <PDBx:U33>0.4629</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1820">
         <PDBx:U11>0.4713</PDBx:U11>
         <PDBx:U12>-0.2657</PDBx:U12>
         <PDBx:U13>0.0581</PDBx:U13>
         <PDBx:U22>0.9067</PDBx:U22>
         <PDBx:U23>-0.0840</PDBx:U23>
         <PDBx:U33>0.4949</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1821">
         <PDBx:U11>0.5080</PDBx:U11>
         <PDBx:U12>-0.2973</PDBx:U12>
         <PDBx:U13>0.0432</PDBx:U13>
         <PDBx:U22>1.0243</PDBx:U22>
         <PDBx:U23>-0.0962</PDBx:U23>
         <PDBx:U33>0.5091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1822">
         <PDBx:U11>0.5062</PDBx:U11>
         <PDBx:U12>-0.3181</PDBx:U12>
         <PDBx:U13>0.0455</PDBx:U13>
         <PDBx:U22>1.0338</PDBx:U22>
         <PDBx:U23>-0.1046</PDBx:U23>
         <PDBx:U33>0.4632</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1823">
         <PDBx:U11>0.4089</PDBx:U11>
         <PDBx:U12>-0.2825</PDBx:U12>
         <PDBx:U13>0.0770</PDBx:U13>
         <PDBx:U22>0.7879</PDBx:U22>
         <PDBx:U23>-0.1234</PDBx:U23>
         <PDBx:U33>0.4580</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1824">
         <PDBx:U11>0.3885</PDBx:U11>
         <PDBx:U12>-0.2573</PDBx:U12>
         <PDBx:U13>0.0901</PDBx:U13>
         <PDBx:U22>0.6882</PDBx:U22>
         <PDBx:U23>-0.1202</PDBx:U23>
         <PDBx:U33>0.4513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1825">
         <PDBx:U11>0.4257</PDBx:U11>
         <PDBx:U12>-0.2661</PDBx:U12>
         <PDBx:U13>0.1065</PDBx:U13>
         <PDBx:U22>0.6808</PDBx:U22>
         <PDBx:U23>-0.1385</PDBx:U23>
         <PDBx:U33>0.4783</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1826">
         <PDBx:U11>0.4227</PDBx:U11>
         <PDBx:U12>-0.2248</PDBx:U12>
         <PDBx:U13>0.0892</PDBx:U13>
         <PDBx:U22>0.6832</PDBx:U22>
         <PDBx:U23>-0.1040</PDBx:U23>
         <PDBx:U33>0.5103</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1827">
         <PDBx:U11>0.3895</PDBx:U11>
         <PDBx:U12>-0.2398</PDBx:U12>
         <PDBx:U13>0.1125</PDBx:U13>
         <PDBx:U22>0.5853</PDBx:U22>
         <PDBx:U23>-0.1346</PDBx:U23>
         <PDBx:U33>0.4645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1828">
         <PDBx:U11>0.3558</PDBx:U11>
         <PDBx:U12>-0.2145</PDBx:U12>
         <PDBx:U13>0.1015</PDBx:U13>
         <PDBx:U22>0.5524</PDBx:U22>
         <PDBx:U23>-0.1136</PDBx:U23>
         <PDBx:U33>0.4484</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1829">
         <PDBx:U11>0.5367</PDBx:U11>
         <PDBx:U12>-0.3023</PDBx:U12>
         <PDBx:U13>0.0291</PDBx:U13>
         <PDBx:U22>1.1102</PDBx:U22>
         <PDBx:U23>-0.0996</PDBx:U23>
         <PDBx:U33>0.5680</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1830">
         <PDBx:U11>0.5814</PDBx:U11>
         <PDBx:U12>-0.3330</PDBx:U12>
         <PDBx:U13>0.0115</PDBx:U13>
         <PDBx:U22>1.2417</PDBx:U22>
         <PDBx:U23>-0.1155</PDBx:U23>
         <PDBx:U33>0.6004</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1831">
         <PDBx:U11>0.6216</PDBx:U11>
         <PDBx:U12>-0.3166</PDBx:U12>
         <PDBx:U13>-0.0135</PDBx:U13>
         <PDBx:U22>1.3360</PDBx:U22>
         <PDBx:U23>-0.0797</PDBx:U23>
         <PDBx:U33>0.5982</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1832">
         <PDBx:U11>0.6670</PDBx:U11>
         <PDBx:U12>-0.3433</PDBx:U12>
         <PDBx:U13>-0.0275</PDBx:U13>
         <PDBx:U22>1.4395</PDBx:U22>
         <PDBx:U23>-0.0930</PDBx:U23>
         <PDBx:U33>0.6076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1833">
         <PDBx:U11>0.5901</PDBx:U11>
         <PDBx:U12>-0.3298</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>1.2842</PDBx:U22>
         <PDBx:U23>-0.1224</PDBx:U23>
         <PDBx:U33>0.6522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1834">
         <PDBx:U11>0.6497</PDBx:U11>
         <PDBx:U12>-0.2720</PDBx:U12>
         <PDBx:U13>-0.0188</PDBx:U13>
         <PDBx:U22>1.3415</PDBx:U22>
         <PDBx:U23>-0.0343</PDBx:U23>
         <PDBx:U33>0.6274</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1835">
         <PDBx:U11>0.7510</PDBx:U11>
         <PDBx:U12>-0.2482</PDBx:U12>
         <PDBx:U13>-0.0420</PDBx:U13>
         <PDBx:U22>1.4836</PDBx:U22>
         <PDBx:U23>0.0077</PDBx:U23>
         <PDBx:U33>0.6887</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1836">
         <PDBx:U11>0.8631</PDBx:U11>
         <PDBx:U12>-0.2664</PDBx:U12>
         <PDBx:U13>-0.0338</PDBx:U13>
         <PDBx:U22>1.5723</PDBx:U22>
         <PDBx:U23>0.0060</PDBx:U23>
         <PDBx:U33>0.7275</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1837">
         <PDBx:U11>0.9530</PDBx:U11>
         <PDBx:U12>-0.2506</PDBx:U12>
         <PDBx:U13>-0.0515</PDBx:U13>
         <PDBx:U22>1.6896</PDBx:U22>
         <PDBx:U23>0.0407</PDBx:U23>
         <PDBx:U33>0.7681</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1838">
         <PDBx:U11>0.7587</PDBx:U11>
         <PDBx:U12>-0.1967</PDBx:U12>
         <PDBx:U13>-0.0412</PDBx:U13>
         <PDBx:U22>1.4536</PDBx:U22>
         <PDBx:U23>0.0544</PDBx:U23>
         <PDBx:U33>0.7153</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1839">
         <PDBx:U11>0.8456</PDBx:U11>
         <PDBx:U12>-0.2987</PDBx:U12>
         <PDBx:U13>-0.0057</PDBx:U13>
         <PDBx:U22>1.5022</PDBx:U22>
         <PDBx:U23>-0.0337</PDBx:U23>
         <PDBx:U33>0.7018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1840">
         <PDBx:U11>0.9054</PDBx:U11>
         <PDBx:U12>-0.3200</PDBx:U12>
         <PDBx:U13>0.0098</PDBx:U13>
         <PDBx:U22>1.5342</PDBx:U22>
         <PDBx:U23>-0.0416</PDBx:U23>
         <PDBx:U33>0.6960</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1841">
         <PDBx:U11>0.8894</PDBx:U11>
         <PDBx:U12>-0.3722</PDBx:U12>
         <PDBx:U13>0.0158</PDBx:U13>
         <PDBx:U22>1.5482</PDBx:U22>
         <PDBx:U23>-0.0943</PDBx:U23>
         <PDBx:U33>0.6624</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1842">
         <PDBx:U11>0.9382</PDBx:U11>
         <PDBx:U12>-0.3959</PDBx:U12>
         <PDBx:U13>0.0250</PDBx:U13>
         <PDBx:U22>1.5941</PDBx:U22>
         <PDBx:U23>-0.1045</PDBx:U23>
         <PDBx:U33>0.6492</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1843">
         <PDBx:U11>0.8985</PDBx:U11>
         <PDBx:U12>-0.3093</PDBx:U12>
         <PDBx:U13>0.0440</PDBx:U13>
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         <PDBx:U23>-0.0417</PDBx:U23>
         <PDBx:U33>0.6951</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.8787</PDBx:U11>
         <PDBx:U12>-0.2622</PDBx:U12>
         <PDBx:U13>0.0430</PDBx:U13>
         <PDBx:U22>1.3740</PDBx:U22>
         <PDBx:U23>0.0071</PDBx:U23>
         <PDBx:U33>0.6839</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1845">
         <PDBx:U11>0.9158</PDBx:U11>
         <PDBx:U12>-0.2388</PDBx:U12>
         <PDBx:U13>0.0309</PDBx:U13>
         <PDBx:U22>1.4249</PDBx:U22>
         <PDBx:U23>0.0540</PDBx:U23>
         <PDBx:U33>0.6713</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1846">
         <PDBx:U11>0.8035</PDBx:U11>
         <PDBx:U12>-0.2341</PDBx:U12>
         <PDBx:U13>0.0535</PDBx:U13>
         <PDBx:U22>1.2463</PDBx:U22>
         <PDBx:U23>0.0155</PDBx:U23>
         <PDBx:U33>0.6589</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1847">
         <PDBx:U11>0.8879</PDBx:U11>
         <PDBx:U12>-0.1991</PDBx:U12>
         <PDBx:U13>0.0366</PDBx:U13>
         <PDBx:U22>1.3528</PDBx:U22>
         <PDBx:U23>0.0882</PDBx:U23>
         <PDBx:U33>0.6674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1848">
         <PDBx:U11>0.8181</PDBx:U11>
         <PDBx:U12>-0.1966</PDBx:U12>
         <PDBx:U13>0.0500</PDBx:U13>
         <PDBx:U22>1.2444</PDBx:U22>
         <PDBx:U23>0.0640</PDBx:U23>
         <PDBx:U33>0.6579</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>550</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>250</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1849">
         <PDBx:U11>0.8027</PDBx:U11>
         <PDBx:U12>-0.3912</PDBx:U12>
         <PDBx:U13>0.0138</PDBx:U13>
         <PDBx:U22>1.4861</PDBx:U22>
         <PDBx:U23>-0.1284</PDBx:U23>
         <PDBx:U33>0.6283</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1850">
         <PDBx:U11>0.7774</PDBx:U11>
         <PDBx:U12>-0.4397</PDBx:U12>
         <PDBx:U13>0.0235</PDBx:U13>
         <PDBx:U22>1.4835</PDBx:U22>
         <PDBx:U23>-0.1806</PDBx:U23>
         <PDBx:U33>0.5961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1851">
         <PDBx:U11>0.7278</PDBx:U11>
         <PDBx:U12>-0.4490</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>1.5142</PDBx:U22>
         <PDBx:U23>-0.1748</PDBx:U23>
         <PDBx:U33>0.5130</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1852">
         <PDBx:U11>0.7728</PDBx:U11>
         <PDBx:U12>-0.4764</PDBx:U12>
         <PDBx:U13>0.0147</PDBx:U13>
         <PDBx:U22>1.5606</PDBx:U22>
         <PDBx:U23>-0.2011</PDBx:U23>
         <PDBx:U33>0.5346</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1853">
         <PDBx:U11>0.7286</PDBx:U11>
         <PDBx:U12>-0.4307</PDBx:U12>
         <PDBx:U13>0.0419</PDBx:U13>
         <PDBx:U22>1.3967</PDBx:U22>
         <PDBx:U23>-0.2014</PDBx:U23>
         <PDBx:U33>0.6100</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>551</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>A</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>251</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1854">
         <PDBx:U11>0.6913</PDBx:U11>
         <PDBx:U12>0.3473</PDBx:U12>
         <PDBx:U13>-0.2148</PDBx:U13>
         <PDBx:U22>1.0058</PDBx:U22>
         <PDBx:U23>0.0875</PDBx:U23>
         <PDBx:U33>1.0663</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1855">
         <PDBx:U11>0.6834</PDBx:U11>
         <PDBx:U12>0.3387</PDBx:U12>
         <PDBx:U13>-0.1948</PDBx:U13>
         <PDBx:U22>1.0053</PDBx:U22>
         <PDBx:U23>0.0497</PDBx:U23>
         <PDBx:U33>1.0458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1856">
         <PDBx:U11>0.6339</PDBx:U11>
         <PDBx:U12>0.3047</PDBx:U12>
         <PDBx:U13>-0.1815</PDBx:U13>
         <PDBx:U22>0.9795</PDBx:U22>
         <PDBx:U23>0.0479</PDBx:U23>
         <PDBx:U33>0.9693</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1857">
         <PDBx:U11>0.6256</PDBx:U11>
         <PDBx:U12>0.2974</PDBx:U12>
         <PDBx:U13>-0.1694</PDBx:U13>
         <PDBx:U22>1.0343</PDBx:U22>
         <PDBx:U23>0.0177</PDBx:U23>
         <PDBx:U33>0.9613</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1858">
         <PDBx:U11>0.7058</PDBx:U11>
         <PDBx:U12>0.3415</PDBx:U12>
         <PDBx:U13>-0.1919</PDBx:U13>
         <PDBx:U22>0.9583</PDBx:U22>
         <PDBx:U23>0.0570</PDBx:U23>
         <PDBx:U33>1.0592</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>306</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1859">
         <PDBx:U11>0.5743</PDBx:U11>
         <PDBx:U12>0.2819</PDBx:U12>
         <PDBx:U13>-0.1829</PDBx:U13>
         <PDBx:U22>0.8695</PDBx:U22>
         <PDBx:U23>0.0801</PDBx:U23>
         <PDBx:U33>0.8865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>307</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>307</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>307</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>0.1072</PDBx:U23>
         <PDBx:U33>0.7858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>307</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0971</PDBx:U23>
         <PDBx:U33>0.8207</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>308</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U23>0.1017</PDBx:U23>
         <PDBx:U33>0.8257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>308</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>0.0713</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>308</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U22>1.0816</PDBx:U22>
         <PDBx:U23>0.0693</PDBx:U23>
         <PDBx:U33>0.8553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>308</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U22>0.9629</PDBx:U22>
         <PDBx:U23>0.1333</PDBx:U23>
         <PDBx:U33>0.8977</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>308</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1876">
         <PDBx:U11>0.4279</PDBx:U11>
         <PDBx:U12>0.2661</PDBx:U12>
         <PDBx:U13>-0.1471</PDBx:U13>
         <PDBx:U22>1.0873</PDBx:U22>
         <PDBx:U23>-0.0490</PDBx:U23>
         <PDBx:U33>0.7607</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1877">
         <PDBx:U11>0.6089</PDBx:U11>
         <PDBx:U12>0.3277</PDBx:U12>
         <PDBx:U13>-0.1894</PDBx:U13>
         <PDBx:U22>1.1760</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.9800</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1878">
         <PDBx:U11>0.6089</PDBx:U11>
         <PDBx:U12>0.3277</PDBx:U12>
         <PDBx:U13>-0.1890</PDBx:U13>
         <PDBx:U22>1.1742</PDBx:U22>
         <PDBx:U23>-0.0034</PDBx:U23>
         <PDBx:U33>0.9800</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1879">
         <PDBx:U11>0.6060</PDBx:U11>
         <PDBx:U12>0.3310</PDBx:U12>
         <PDBx:U13>-0.1811</PDBx:U13>
         <PDBx:U22>1.1362</PDBx:U22>
         <PDBx:U23>-0.0148</PDBx:U23>
         <PDBx:U33>0.9807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1880">
         <PDBx:U11>0.6549</PDBx:U11>
         <PDBx:U12>0.3499</PDBx:U12>
         <PDBx:U13>-0.2132</PDBx:U13>
         <PDBx:U22>1.1804</PDBx:U22>
         <PDBx:U23>0.0297</PDBx:U23>
         <PDBx:U33>1.0433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>309</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1881">
         <PDBx:U11>0.3985</PDBx:U11>
         <PDBx:U12>0.2461</PDBx:U12>
         <PDBx:U13>-0.1450</PDBx:U13>
         <PDBx:U22>0.9608</PDBx:U22>
         <PDBx:U23>-0.0125</PDBx:U23>
         <PDBx:U33>0.7049</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1882">
         <PDBx:U11>0.4111</PDBx:U11>
         <PDBx:U12>0.2165</PDBx:U12>
         <PDBx:U13>-0.1226</PDBx:U13>
         <PDBx:U22>1.0008</PDBx:U22>
         <PDBx:U23>-0.0365</PDBx:U23>
         <PDBx:U33>0.7090</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1883">
         <PDBx:U11>0.3977</PDBx:U11>
         <PDBx:U12>0.1920</PDBx:U12>
         <PDBx:U13>-0.1146</PDBx:U13>
         <PDBx:U22>1.0255</PDBx:U22>
         <PDBx:U23>-0.0409</PDBx:U23>
         <PDBx:U33>0.6799</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1884">
         <PDBx:U11>0.3984</PDBx:U11>
         <PDBx:U12>0.1908</PDBx:U12>
         <PDBx:U13>-0.1229</PDBx:U13>
         <PDBx:U22>1.0153</PDBx:U22>
         <PDBx:U23>-0.0197</PDBx:U23>
         <PDBx:U33>0.6658</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1885">
         <PDBx:U11>0.3310</PDBx:U11>
         <PDBx:U12>0.2005</PDBx:U12>
         <PDBx:U13>-0.1155</PDBx:U13>
         <PDBx:U22>0.8690</PDBx:U22>
         <PDBx:U23>-0.0232</PDBx:U23>
         <PDBx:U33>0.6169</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1886">
         <PDBx:U11>0.3455</PDBx:U11>
         <PDBx:U12>0.2036</PDBx:U12>
         <PDBx:U13>-0.1069</PDBx:U13>
         <PDBx:U22>0.8769</PDBx:U22>
         <PDBx:U23>-0.0426</PDBx:U23>
         <PDBx:U33>0.6446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1887">
         <PDBx:U11>0.4236</PDBx:U11>
         <PDBx:U12>0.2406</PDBx:U12>
         <PDBx:U13>-0.1196</PDBx:U13>
         <PDBx:U22>0.9528</PDBx:U22>
         <PDBx:U23>-0.0529</PDBx:U23>
         <PDBx:U33>0.7450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1888">
         <PDBx:U11>0.3347</PDBx:U11>
         <PDBx:U12>0.1926</PDBx:U12>
         <PDBx:U13>-0.1051</PDBx:U13>
         <PDBx:U22>0.8085</PDBx:U22>
         <PDBx:U23>-0.0214</PDBx:U23>
         <PDBx:U33>0.6210</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>310</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1889">
         <PDBx:U11>0.3237</PDBx:U11>
         <PDBx:U12>0.1709</PDBx:U12>
         <PDBx:U13>-0.0986</PDBx:U13>
         <PDBx:U22>0.9951</PDBx:U22>
         <PDBx:U23>-0.0694</PDBx:U23>
         <PDBx:U33>0.6082</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1890">
         <PDBx:U11>0.3763</PDBx:U11>
         <PDBx:U12>0.1432</PDBx:U12>
         <PDBx:U13>-0.0894</PDBx:U13>
         <PDBx:U22>1.0749</PDBx:U22>
         <PDBx:U23>-0.0766</PDBx:U23>
         <PDBx:U33>0.6463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1891">
         <PDBx:U11>0.3518</PDBx:U11>
         <PDBx:U12>0.1130</PDBx:U12>
         <PDBx:U13>-0.0778</PDBx:U13>
         <PDBx:U22>1.0122</PDBx:U22>
         <PDBx:U23>-0.0672</PDBx:U23>
         <PDBx:U33>0.6077</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1892">
         <PDBx:U11>0.2628</PDBx:U11>
         <PDBx:U12>0.1105</PDBx:U12>
         <PDBx:U13>-0.0741</PDBx:U13>
         <PDBx:U22>0.8874</PDBx:U22>
         <PDBx:U23>-0.0598</PDBx:U23>
         <PDBx:U33>0.5214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1893">
         <PDBx:U11>0.3129</PDBx:U11>
         <PDBx:U12>0.1296</PDBx:U12>
         <PDBx:U13>-0.0787</PDBx:U13>
         <PDBx:U22>1.0670</PDBx:U22>
         <PDBx:U23>-0.1083</PDBx:U23>
         <PDBx:U33>0.5903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1894">
         <PDBx:U11>0.2968</PDBx:U11>
         <PDBx:U12>0.1109</PDBx:U12>
         <PDBx:U13>-0.0647</PDBx:U13>
         <PDBx:U22>1.0432</PDBx:U22>
         <PDBx:U23>-0.1213</PDBx:U23>
         <PDBx:U33>0.5780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1895">
         <PDBx:U11>0.4148</PDBx:U11>
         <PDBx:U12>0.1607</PDBx:U12>
         <PDBx:U13>-0.0899</PDBx:U13>
         <PDBx:U22>1.2108</PDBx:U22>
         <PDBx:U23>-0.1196</PDBx:U23>
         <PDBx:U33>0.7094</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>311</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1896">
         <PDBx:U11>0.3337</PDBx:U11>
         <PDBx:U12>0.0908</PDBx:U12>
         <PDBx:U13>-0.0724</PDBx:U13>
         <PDBx:U22>1.0021</PDBx:U22>
         <PDBx:U23>-0.0686</PDBx:U23>
         <PDBx:U33>0.5761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1897">
         <PDBx:U11>0.3114</PDBx:U11>
         <PDBx:U12>0.0624</PDBx:U12>
         <PDBx:U13>-0.0621</PDBx:U13>
         <PDBx:U22>0.9432</PDBx:U22>
         <PDBx:U23>-0.0609</PDBx:U23>
         <PDBx:U33>0.5435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1898">
         <PDBx:U11>0.2953</PDBx:U11>
         <PDBx:U12>0.0399</PDBx:U12>
         <PDBx:U13>-0.0484</PDBx:U13>
         <PDBx:U22>0.9141</PDBx:U22>
         <PDBx:U23>-0.0712</PDBx:U23>
         <PDBx:U33>0.5351</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1899">
         <PDBx:U11>0.2080</PDBx:U11>
         <PDBx:U12>0.0307</PDBx:U12>
         <PDBx:U13>-0.0442</PDBx:U13>
         <PDBx:U22>0.7856</PDBx:U22>
         <PDBx:U23>-0.0570</PDBx:U23>
         <PDBx:U33>0.4462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1900">
         <PDBx:U11>0.3459</PDBx:U11>
         <PDBx:U12>0.0424</PDBx:U12>
         <PDBx:U13>-0.0578</PDBx:U13>
         <PDBx:U22>0.9949</PDBx:U22>
         <PDBx:U23>-0.0702</PDBx:U23>
         <PDBx:U33>0.5677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>312</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>12</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1901">
         <PDBx:U11>0.2773</PDBx:U11>
         <PDBx:U12>0.0298</PDBx:U12>
         <PDBx:U13>-0.0415</PDBx:U13>
         <PDBx:U22>0.9331</PDBx:U22>
         <PDBx:U23>-0.0944</PDBx:U23>
         <PDBx:U33>0.5236</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1902">
         <PDBx:U11>0.2733</PDBx:U11>
         <PDBx:U12>0.0062</PDBx:U12>
         <PDBx:U13>-0.0285</PDBx:U13>
         <PDBx:U22>0.9220</PDBx:U22>
         <PDBx:U23>-0.1031</PDBx:U23>
         <PDBx:U33>0.5228</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1903">
         <PDBx:U11>0.2825</PDBx:U11>
         <PDBx:U12>0.0221</PDBx:U12>
         <PDBx:U13>-0.0290</PDBx:U13>
         <PDBx:U22>0.9199</PDBx:U22>
         <PDBx:U23>-0.0995</PDBx:U23>
         <PDBx:U33>0.5403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1904">
         <PDBx:U11>0.2548</PDBx:U11>
         <PDBx:U12>0.0019</PDBx:U12>
         <PDBx:U13>-0.0192</PDBx:U13>
         <PDBx:U22>0.8657</PDBx:U22>
         <PDBx:U23>-0.0949</PDBx:U23>
         <PDBx:U33>0.5099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1905">
         <PDBx:U11>0.2959</PDBx:U11>
         <PDBx:U12>-0.0049</PDBx:U12>
         <PDBx:U13>-0.0231</PDBx:U13>
         <PDBx:U22>0.9934</PDBx:U22>
         <PDBx:U23>-0.1274</PDBx:U23>
         <PDBx:U33>0.5488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1906">
         <PDBx:U11>0.4128</PDBx:U11>
         <PDBx:U12>-0.0263</PDBx:U12>
         <PDBx:U13>-0.0210</PDBx:U13>
         <PDBx:U22>1.1170</PDBx:U22>
         <PDBx:U23>-0.1331</PDBx:U23>
         <PDBx:U33>0.6594</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1907">
         <PDBx:U11>0.4357</PDBx:U11>
         <PDBx:U12>-0.0456</PDBx:U12>
         <PDBx:U13>-0.0175</PDBx:U13>
         <PDBx:U22>1.0967</PDBx:U22>
         <PDBx:U23>-0.1213</PDBx:U23>
         <PDBx:U33>0.6758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1908">
         <PDBx:U11>0.5109</PDBx:U11>
         <PDBx:U12>-0.0228</PDBx:U12>
         <PDBx:U13>-0.0231</PDBx:U13>
         <PDBx:U22>1.2641</PDBx:U22>
         <PDBx:U23>-0.1505</PDBx:U23>
         <PDBx:U33>0.7607</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>313</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>13</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1909">
         <PDBx:U11>0.2411</PDBx:U11>
         <PDBx:U12>0.0589</PDBx:U12>
         <PDBx:U13>-0.0412</PDBx:U13>
         <PDBx:U22>0.8960</PDBx:U22>
         <PDBx:U23>-0.1015</PDBx:U23>
         <PDBx:U33>0.5091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1910">
         <PDBx:U11>0.3040</PDBx:U11>
         <PDBx:U12>0.0801</PDBx:U12>
         <PDBx:U13>-0.0443</PDBx:U13>
         <PDBx:U22>0.9462</PDBx:U22>
         <PDBx:U23>-0.1015</PDBx:U23>
         <PDBx:U33>0.5833</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1911">
         <PDBx:U11>0.2417</PDBx:U11>
         <PDBx:U12>0.0808</PDBx:U12>
         <PDBx:U13>-0.0479</PDBx:U13>
         <PDBx:U22>0.8279</PDBx:U22>
         <PDBx:U23>-0.0745</PDBx:U23>
         <PDBx:U33>0.5154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1912">
         <PDBx:U11>0.2321</PDBx:U11>
         <PDBx:U12>0.0768</PDBx:U12>
         <PDBx:U13>-0.0425</PDBx:U13>
         <PDBx:U22>0.8002</PDBx:U22>
         <PDBx:U23>-0.0743</PDBx:U23>
         <PDBx:U33>0.5100</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1913">
         <PDBx:U11>0.3320</PDBx:U11>
         <PDBx:U12>0.1223</PDBx:U12>
         <PDBx:U13>-0.0595</PDBx:U13>
         <PDBx:U22>0.9964</PDBx:U22>
         <PDBx:U23>-0.1089</PDBx:U23>
         <PDBx:U33>0.6257</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1914">
         <PDBx:U11>0.3562</PDBx:U11>
         <PDBx:U12>0.1252</PDBx:U12>
         <PDBx:U13>-0.0553</PDBx:U13>
         <PDBx:U22>1.0809</PDBx:U22>
         <PDBx:U23>-0.1393</PDBx:U23>
         <PDBx:U33>0.6598</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1915">
         <PDBx:U11>0.4235</PDBx:U11>
         <PDBx:U12>0.1682</PDBx:U12>
         <PDBx:U13>-0.0714</PDBx:U13>
         <PDBx:U22>1.1663</PDBx:U22>
         <PDBx:U23>-0.1454</PDBx:U23>
         <PDBx:U33>0.7448</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1916">
         <PDBx:U11>0.4489</PDBx:U11>
         <PDBx:U12>0.1894</PDBx:U12>
         <PDBx:U13>-0.0869</PDBx:U13>
         <PDBx:U22>1.1722</PDBx:U22>
         <PDBx:U23>-0.1245</PDBx:U23>
         <PDBx:U33>0.7704</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1917">
         <PDBx:U11>0.4386</PDBx:U11>
         <PDBx:U12>0.1802</PDBx:U12>
         <PDBx:U13>-0.0685</PDBx:U13>
         <PDBx:U22>1.2183</PDBx:U22>
         <PDBx:U23>-0.1732</PDBx:U23>
         <PDBx:U33>0.7748</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>314</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>14</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1918">
         <PDBx:U11>0.2236</PDBx:U11>
         <PDBx:U12>0.0850</PDBx:U12>
         <PDBx:U13>-0.0570</PDBx:U13>
         <PDBx:U22>0.7863</PDBx:U22>
         <PDBx:U23>-0.0524</PDBx:U23>
         <PDBx:U33>0.4863</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1919">
         <PDBx:U11>0.2877</PDBx:U11>
         <PDBx:U12>0.0835</PDBx:U12>
         <PDBx:U13>-0.0611</PDBx:U13>
         <PDBx:U22>0.7986</PDBx:U22>
         <PDBx:U23>-0.0238</PDBx:U23>
         <PDBx:U33>0.5404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1920">
         <PDBx:U11>0.2115</PDBx:U11>
         <PDBx:U12>0.0446</PDBx:U12>
         <PDBx:U13>-0.0443</PDBx:U13>
         <PDBx:U22>0.7042</PDBx:U22>
         <PDBx:U23>-0.0220</PDBx:U23>
         <PDBx:U33>0.4599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1921">
         <PDBx:U11>0.1956</PDBx:U11>
         <PDBx:U12>0.0411</PDBx:U12>
         <PDBx:U13>-0.0424</PDBx:U13>
         <PDBx:U22>0.6594</PDBx:U22>
         <PDBx:U23>-0.0090</PDBx:U23>
         <PDBx:U33>0.4447</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1922">
         <PDBx:U11>0.3156</PDBx:U11>
         <PDBx:U12>0.0886</PDBx:U12>
         <PDBx:U13>-0.0711</PDBx:U13>
         <PDBx:U22>0.8123</PDBx:U22>
         <PDBx:U23>-0.0033</PDBx:U23>
         <PDBx:U33>0.5516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1923">
         <PDBx:U11>0.2831</PDBx:U11>
         <PDBx:U12>0.0826</PDBx:U12>
         <PDBx:U13>-0.0736</PDBx:U13>
         <PDBx:U22>0.7268</PDBx:U22>
         <PDBx:U23>0.0277</PDBx:U23>
         <PDBx:U33>0.5020</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1924">
         <PDBx:U11>0.4056</PDBx:U11>
         <PDBx:U12>0.1147</PDBx:U12>
         <PDBx:U13>-0.0909</PDBx:U13>
         <PDBx:U22>0.7899</PDBx:U22>
         <PDBx:U23>0.0544</PDBx:U23>
         <PDBx:U33>0.6182</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1925">
         <PDBx:U11>0.2744</PDBx:U11>
         <PDBx:U12>0.1406</PDBx:U12>
         <PDBx:U13>-0.1101</PDBx:U13>
         <PDBx:U22>0.6609</PDBx:U22>
         <PDBx:U23>0.0630</PDBx:U23>
         <PDBx:U33>0.4805</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>315</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>15</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1926">
         <PDBx:U11>0.2023</PDBx:U11>
         <PDBx:U12>0.0152</PDBx:U12>
         <PDBx:U13>-0.0332</PDBx:U13>
         <PDBx:U22>0.7063</PDBx:U22>
         <PDBx:U23>-0.0330</PDBx:U23>
         <PDBx:U33>0.4453</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1927">
         <PDBx:U11>0.2145</PDBx:U11>
         <PDBx:U12>-0.0223</PDBx:U12>
         <PDBx:U13>-0.0189</PDBx:U13>
         <PDBx:U22>0.6848</PDBx:U22>
         <PDBx:U23>-0.0280</PDBx:U23>
         <PDBx:U33>0.4497</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1928">
         <PDBx:U11>0.2202</PDBx:U11>
         <PDBx:U12>-0.0343</PDBx:U12>
         <PDBx:U13>-0.0090</PDBx:U13>
         <PDBx:U22>0.6899</PDBx:U22>
         <PDBx:U23>-0.0356</PDBx:U23>
         <PDBx:U33>0.4585</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1929">
         <PDBx:U11>0.2293</PDBx:U11>
         <PDBx:U12>-0.0495</PDBx:U12>
         <PDBx:U13>-0.0033</PDBx:U13>
         <PDBx:U22>0.6592</PDBx:U22>
         <PDBx:U23>-0.0204</PDBx:U23>
         <PDBx:U33>0.4609</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1930">
         <PDBx:U11>0.2565</PDBx:U11>
         <PDBx:U12>-0.0452</PDBx:U12>
         <PDBx:U13>-0.0128</PDBx:U13>
         <PDBx:U22>0.7316</PDBx:U22>
         <PDBx:U23>-0.0395</PDBx:U23>
         <PDBx:U33>0.4862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1931">
         <PDBx:U11>0.2442</PDBx:U11>
         <PDBx:U12>-0.0768</PDBx:U12>
         <PDBx:U13>-0.0016</PDBx:U13>
         <PDBx:U22>0.6720</PDBx:U22>
         <PDBx:U23>-0.0318</PDBx:U23>
         <PDBx:U33>0.4662</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1932">
         <PDBx:U11>0.2899</PDBx:U11>
         <PDBx:U12>-0.0381</PDBx:U12>
         <PDBx:U13>-0.0203</PDBx:U13>
         <PDBx:U22>0.7655</PDBx:U22>
         <PDBx:U23>-0.0344</PDBx:U23>
         <PDBx:U33>0.5146</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>316</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>16</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1933">
         <PDBx:U11>0.2345</PDBx:U11>
         <PDBx:U12>-0.0284</PDBx:U12>
         <PDBx:U13>-0.0068</PDBx:U13>
         <PDBx:U22>0.7495</PDBx:U22>
         <PDBx:U23>-0.0592</PDBx:U23>
         <PDBx:U33>0.4797</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1934">
         <PDBx:U11>0.2466</PDBx:U11>
         <PDBx:U12>-0.0393</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.7724</PDBx:U22>
         <PDBx:U23>-0.0705</PDBx:U23>
         <PDBx:U33>0.4918</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1935">
         <PDBx:U11>0.2103</PDBx:U11>
         <PDBx:U12>-0.0204</PDBx:U12>
         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.7273</PDBx:U22>
         <PDBx:U23>-0.0668</PDBx:U23>
         <PDBx:U33>0.4651</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1936">
         <PDBx:U11>0.2182</PDBx:U11>
         <PDBx:U12>-0.0383</PDBx:U12>
         <PDBx:U13>0.0090</PDBx:U13>
         <PDBx:U22>0.7218</PDBx:U22>
         <PDBx:U23>-0.0660</PDBx:U23>
         <PDBx:U33>0.4667</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1937">
         <PDBx:U11>0.3184</PDBx:U11>
         <PDBx:U12>-0.0315</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.9039</PDBx:U22>
         <PDBx:U23>-0.0990</PDBx:U23>
         <PDBx:U33>0.5701</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1938">
         <PDBx:U11>0.3772</PDBx:U11>
         <PDBx:U12>0.0043</PDBx:U12>
         <PDBx:U13>-0.0084</PDBx:U13>
         <PDBx:U22>0.9937</PDBx:U22>
         <PDBx:U23>-0.1087</PDBx:U23>
         <PDBx:U33>0.6422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>317</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>17</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1939">
         <PDBx:U11>0.1884</PDBx:U11>
         <PDBx:U12>0.0178</PDBx:U12>
         <PDBx:U13>-0.0159</PDBx:U13>
         <PDBx:U22>0.7087</PDBx:U22>
         <PDBx:U23>-0.0631</PDBx:U23>
         <PDBx:U33>0.4562</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1940">
         <PDBx:U11>0.2532</PDBx:U11>
         <PDBx:U12>0.0437</PDBx:U12>
         <PDBx:U13>-0.0247</PDBx:U13>
         <PDBx:U22>0.7552</PDBx:U22>
         <PDBx:U23>-0.0572</PDBx:U23>
         <PDBx:U33>0.5317</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0200</PDBx:U13>
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         <PDBx:U23>-0.0240</PDBx:U23>
         <PDBx:U33>0.4801</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1942">
         <PDBx:U11>0.2533</PDBx:U11>
         <PDBx:U12>0.0085</PDBx:U12>
         <PDBx:U13>-0.0140</PDBx:U13>
         <PDBx:U22>0.6435</PDBx:U22>
         <PDBx:U23>-0.0211</PDBx:U23>
         <PDBx:U33>0.4939</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1943">
         <PDBx:U11>0.2866</PDBx:U11>
         <PDBx:U12>0.0926</PDBx:U12>
         <PDBx:U13>-0.0472</PDBx:U13>
         <PDBx:U22>0.7777</PDBx:U22>
         <PDBx:U23>-0.0507</PDBx:U23>
         <PDBx:U33>0.5714</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>318</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>18</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1944">
         <PDBx:U11>0.2286</PDBx:U11>
         <PDBx:U12>0.0063</PDBx:U12>
         <PDBx:U13>-0.0226</PDBx:U13>
         <PDBx:U22>0.6327</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.4697</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="1945">
         <PDBx:U11>0.1894</PDBx:U11>
         <PDBx:U12>-0.0166</PDBx:U12>
         <PDBx:U13>-0.0184</PDBx:U13>
         <PDBx:U22>0.5228</PDBx:U22>
         <PDBx:U23>0.0315</PDBx:U23>
         <PDBx:U33>0.4061</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1946">
         <PDBx:U11>0.1865</PDBx:U11>
         <PDBx:U12>-0.0610</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.5199</PDBx:U22>
         <PDBx:U23>0.0308</PDBx:U23>
         <PDBx:U33>0.4025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1947">
         <PDBx:U11>0.2047</PDBx:U11>
         <PDBx:U12>-0.0752</PDBx:U12>
         <PDBx:U13>0.0035</PDBx:U13>
         <PDBx:U22>0.4854</PDBx:U22>
         <PDBx:U23>0.0494</PDBx:U23>
         <PDBx:U33>0.4032</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1948">
         <PDBx:U11>0.1960</PDBx:U11>
         <PDBx:U12>-0.0187</PDBx:U12>
         <PDBx:U13>-0.0238</PDBx:U13>
         <PDBx:U22>0.5194</PDBx:U22>
         <PDBx:U23>0.0500</PDBx:U23>
         <PDBx:U33>0.4056</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1949">
         <PDBx:U11>0.2190</PDBx:U11>
         <PDBx:U12>0.0198</PDBx:U12>
         <PDBx:U13>-0.0428</PDBx:U13>
         <PDBx:U22>0.5334</PDBx:U22>
         <PDBx:U23>0.0634</PDBx:U23>
         <PDBx:U33>0.4217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1950">
         <PDBx:U11>0.1517</PDBx:U11>
         <PDBx:U12>0.0119</PDBx:U12>
         <PDBx:U13>-0.0450</PDBx:U13>
         <PDBx:U22>0.4661</PDBx:U22>
         <PDBx:U23>0.0790</PDBx:U23>
         <PDBx:U33>0.3452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1951">
         <PDBx:U11>0.2621</PDBx:U11>
         <PDBx:U12>0.0380</PDBx:U12>
         <PDBx:U13>-0.0522</PDBx:U13>
         <PDBx:U22>0.5090</PDBx:U22>
         <PDBx:U23>0.0865</PDBx:U23>
         <PDBx:U33>0.4472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>319</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>19</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1952">
         <PDBx:U11>0.1434</PDBx:U11>
         <PDBx:U12>-0.0753</PDBx:U12>
         <PDBx:U13>0.0077</PDBx:U13>
         <PDBx:U22>0.4943</PDBx:U22>
         <PDBx:U23>0.0101</PDBx:U23>
         <PDBx:U33>0.3573</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1953">
         <PDBx:U11>0.2731</PDBx:U11>
         <PDBx:U12>-0.1005</PDBx:U12>
         <PDBx:U13>0.0188</PDBx:U13>
         <PDBx:U22>0.5835</PDBx:U22>
         <PDBx:U23>0.0111</PDBx:U23>
         <PDBx:U33>0.4666</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1954">
         <PDBx:U11>0.3029</PDBx:U11>
         <PDBx:U12>-0.1056</PDBx:U12>
         <PDBx:U13>0.0244</PDBx:U13>
         <PDBx:U22>0.6253</PDBx:U22>
         <PDBx:U23>0.0046</PDBx:U23>
         <PDBx:U33>0.4940</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1955">
         <PDBx:U11>0.2999</PDBx:U11>
         <PDBx:U12>-0.1178</PDBx:U12>
         <PDBx:U13>0.0290</PDBx:U13>
         <PDBx:U22>0.5721</PDBx:U22>
         <PDBx:U23>0.0171</PDBx:U23>
         <PDBx:U33>0.4702</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1956">
         <PDBx:U11>0.2598</PDBx:U11>
         <PDBx:U12>-0.1088</PDBx:U12>
         <PDBx:U13>0.0211</PDBx:U13>
         <PDBx:U22>0.5928</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.4549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1957">
         <PDBx:U11>0.2931</PDBx:U11>
         <PDBx:U12>-0.1099</PDBx:U12>
         <PDBx:U13>0.0174</PDBx:U13>
         <PDBx:U22>0.6087</PDBx:U22>
         <PDBx:U23>0.0006</PDBx:U23>
         <PDBx:U33>0.4897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1958">
         <PDBx:U11>0.2693</PDBx:U11>
         <PDBx:U12>-0.1200</PDBx:U12>
         <PDBx:U13>0.0188</PDBx:U13>
         <PDBx:U22>0.6147</PDBx:U22>
         <PDBx:U23>-0.0135</PDBx:U23>
         <PDBx:U33>0.4705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1959">
         <PDBx:U11>0.2853</PDBx:U11>
         <PDBx:U12>-0.1150</PDBx:U12>
         <PDBx:U13>0.0201</PDBx:U13>
         <PDBx:U22>0.5287</PDBx:U22>
         <PDBx:U23>0.0172</PDBx:U23>
         <PDBx:U33>0.4688</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>320</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>20</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1960">
         <PDBx:U11>0.2686</PDBx:U11>
         <PDBx:U12>-0.0894</PDBx:U12>
         <PDBx:U13>0.0232</PDBx:U13>
         <PDBx:U22>0.6593</PDBx:U22>
         <PDBx:U23>-0.0204</PDBx:U23>
         <PDBx:U33>0.4810</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1961">
         <PDBx:U11>0.3028</PDBx:U11>
         <PDBx:U12>-0.0911</PDBx:U12>
         <PDBx:U13>0.0296</PDBx:U13>
         <PDBx:U22>0.7195</PDBx:U22>
         <PDBx:U23>-0.0373</PDBx:U23>
         <PDBx:U33>0.5169</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1962">
         <PDBx:U11>0.3180</PDBx:U11>
         <PDBx:U12>-0.0906</PDBx:U12>
         <PDBx:U13>0.0278</PDBx:U13>
         <PDBx:U22>0.7059</PDBx:U22>
         <PDBx:U23>-0.0234</PDBx:U23>
         <PDBx:U33>0.5344</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1963">
         <PDBx:U11>0.3095</PDBx:U11>
         <PDBx:U12>-0.1039</PDBx:U12>
         <PDBx:U13>0.0352</PDBx:U13>
         <PDBx:U22>0.6932</PDBx:U22>
         <PDBx:U23>-0.0294</PDBx:U23>
         <PDBx:U33>0.5155</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1964">
         <PDBx:U11>0.4079</PDBx:U11>
         <PDBx:U12>-0.0605</PDBx:U12>
         <PDBx:U13>0.0265</PDBx:U13>
         <PDBx:U22>0.8998</PDBx:U22>
         <PDBx:U23>-0.0753</PDBx:U23>
         <PDBx:U33>0.6486</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1965">
         <PDBx:U11>0.5206</PDBx:U11>
         <PDBx:U12>-0.0601</PDBx:U12>
         <PDBx:U13>0.0344</PDBx:U13>
         <PDBx:U22>1.0464</PDBx:U22>
         <PDBx:U23>-0.1022</PDBx:U23>
         <PDBx:U33>0.7640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1966">
         <PDBx:U11>0.5404</PDBx:U11>
         <PDBx:U12>-0.0929</PDBx:U12>
         <PDBx:U13>0.0446</PDBx:U13>
         <PDBx:U22>1.0525</PDBx:U22>
         <PDBx:U23>-0.0953</PDBx:U23>
         <PDBx:U33>0.7563</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1967">
         <PDBx:U11>0.5787</PDBx:U11>
         <PDBx:U12>-0.0214</PDBx:U12>
         <PDBx:U13>0.0277</PDBx:U13>
         <PDBx:U22>1.1393</PDBx:U22>
         <PDBx:U23>-0.1312</PDBx:U23>
         <PDBx:U33>0.8504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>321</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>21</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1968">
         <PDBx:U11>0.3139</PDBx:U11>
         <PDBx:U12>0.0090</PDBx:U12>
         <PDBx:U13>0.0069</PDBx:U13>
         <PDBx:U22>0.4550</PDBx:U22>
         <PDBx:U23>-0.1040</PDBx:U23>
         <PDBx:U33>0.4688</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1969">
         <PDBx:U11>0.3463</PDBx:U11>
         <PDBx:U12>0.0130</PDBx:U12>
         <PDBx:U13>0.0151</PDBx:U13>
         <PDBx:U22>0.4589</PDBx:U22>
         <PDBx:U23>-0.0916</PDBx:U23>
         <PDBx:U33>0.4907</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1970">
         <PDBx:U11>0.2698</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>0.0151</PDBx:U13>
         <PDBx:U22>0.3620</PDBx:U22>
         <PDBx:U23>-0.0844</PDBx:U23>
         <PDBx:U33>0.3832</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1971">
         <PDBx:U11>0.3464</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0218</PDBx:U13>
         <PDBx:U22>0.4167</PDBx:U22>
         <PDBx:U23>-0.0760</PDBx:U23>
         <PDBx:U33>0.4470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1972">
         <PDBx:U11>0.3998</PDBx:U11>
         <PDBx:U12>0.0402</PDBx:U12>
         <PDBx:U13>0.0078</PDBx:U13>
         <PDBx:U22>0.5085</PDBx:U22>
         <PDBx:U23>-0.0748</PDBx:U23>
         <PDBx:U33>0.5438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>322</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>22</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1973">
         <PDBx:U11>0.2772</PDBx:U11>
         <PDBx:U12>-0.0141</PDBx:U12>
         <PDBx:U13>0.0093</PDBx:U13>
         <PDBx:U22>0.3774</PDBx:U22>
         <PDBx:U23>-0.0885</PDBx:U23>
         <PDBx:U33>0.3802</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1974">
         <PDBx:U11>0.2384</PDBx:U11>
         <PDBx:U12>-0.0248</PDBx:U12>
         <PDBx:U13>0.0088</PDBx:U13>
         <PDBx:U22>0.3222</PDBx:U22>
         <PDBx:U23>-0.0795</PDBx:U23>
         <PDBx:U33>0.3167</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1975">
         <PDBx:U11>0.3049</PDBx:U11>
         <PDBx:U12>-0.0376</PDBx:U12>
         <PDBx:U13>0.0185</PDBx:U13>
         <PDBx:U22>0.3724</PDBx:U22>
         <PDBx:U23>-0.0757</PDBx:U23>
         <PDBx:U33>0.3708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1976">
         <PDBx:U11>0.3044</PDBx:U11>
         <PDBx:U12>-0.0439</PDBx:U12>
         <PDBx:U13>0.0276</PDBx:U13>
         <PDBx:U22>0.3692</PDBx:U22>
         <PDBx:U23>-0.0805</PDBx:U23>
         <PDBx:U33>0.3687</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1977">
         <PDBx:U11>0.2380</PDBx:U11>
         <PDBx:U12>-0.0300</PDBx:U12>
         <PDBx:U13>0.0088</PDBx:U13>
         <PDBx:U22>0.3207</PDBx:U22>
         <PDBx:U23>-0.0793</PDBx:U23>
         <PDBx:U33>0.3028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1978">
         <PDBx:U11>0.2730</PDBx:U11>
         <PDBx:U12>-0.0229</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.3646</PDBx:U22>
         <PDBx:U23>-0.0791</PDBx:U23>
         <PDBx:U33>0.3354</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1979">
         <PDBx:U11>0.3150</PDBx:U11>
         <PDBx:U12>-0.0166</PDBx:U12>
         <PDBx:U13>-0.0038</PDBx:U13>
         <PDBx:U22>0.3934</PDBx:U22>
         <PDBx:U23>-0.0649</PDBx:U23>
         <PDBx:U33>0.3644</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1980">
         <PDBx:U11>0.2825</PDBx:U11>
         <PDBx:U12>-0.0227</PDBx:U12>
         <PDBx:U13>-0.0005</PDBx:U13>
         <PDBx:U22>0.3478</PDBx:U22>
         <PDBx:U23>-0.0587</PDBx:U23>
         <PDBx:U33>0.3195</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1981">
         <PDBx:U11>0.2816</PDBx:U11>
         <PDBx:U12>-0.0037</PDBx:U12>
         <PDBx:U13>-0.0077</PDBx:U13>
         <PDBx:U22>0.3594</PDBx:U22>
         <PDBx:U23>-0.0575</PDBx:U23>
         <PDBx:U33>0.3320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>323</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>23</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1982">
         <PDBx:U11>0.3014</PDBx:U11>
         <PDBx:U12>-0.0405</PDBx:U12>
         <PDBx:U13>0.0166</PDBx:U13>
         <PDBx:U22>0.3613</PDBx:U22>
         <PDBx:U23>-0.0660</PDBx:U23>
         <PDBx:U33>0.3565</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1983">
         <PDBx:U11>0.2851</PDBx:U11>
         <PDBx:U12>-0.0508</PDBx:U12>
         <PDBx:U13>0.0220</PDBx:U13>
         <PDBx:U22>0.3365</PDBx:U22>
         <PDBx:U23>-0.0600</PDBx:U23>
         <PDBx:U33>0.3237</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1984">
         <PDBx:U11>0.2644</PDBx:U11>
         <PDBx:U12>-0.0565</PDBx:U12>
         <PDBx:U13>0.0187</PDBx:U13>
         <PDBx:U22>0.3142</PDBx:U22>
         <PDBx:U23>-0.0534</PDBx:U23>
         <PDBx:U33>0.2859</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1985">
         <PDBx:U11>0.2596</PDBx:U11>
         <PDBx:U12>-0.0534</PDBx:U12>
         <PDBx:U13>0.0145</PDBx:U13>
         <PDBx:U22>0.3096</PDBx:U22>
         <PDBx:U23>-0.0519</PDBx:U23>
         <PDBx:U33>0.2806</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1986">
         <PDBx:U11>0.2849</PDBx:U11>
         <PDBx:U12>-0.0512</PDBx:U12>
         <PDBx:U13>0.0196</PDBx:U13>
         <PDBx:U22>0.3373</PDBx:U22>
         <PDBx:U23>-0.0533</PDBx:U23>
         <PDBx:U33>0.3231</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1987">
         <PDBx:U11>0.3138</PDBx:U11>
         <PDBx:U12>-0.0365</PDBx:U12>
         <PDBx:U13>0.0115</PDBx:U13>
         <PDBx:U22>0.3671</PDBx:U22>
         <PDBx:U23>-0.0466</PDBx:U23>
         <PDBx:U33>0.3539</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1988">
         <PDBx:U11>0.3606</PDBx:U11>
         <PDBx:U12>-0.0273</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.4174</PDBx:U22>
         <PDBx:U23>-0.0544</PDBx:U23>
         <PDBx:U33>0.4110</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>324</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>24</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1989">
         <PDBx:U11>0.3536</PDBx:U11>
         <PDBx:U12>-0.0667</PDBx:U12>
         <PDBx:U13>0.0221</PDBx:U13>
         <PDBx:U22>0.4016</PDBx:U22>
         <PDBx:U23>-0.0516</PDBx:U23>
         <PDBx:U33>0.3604</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1990">
         <PDBx:U11>0.3663</PDBx:U11>
         <PDBx:U12>-0.0756</PDBx:U12>
         <PDBx:U13>0.0195</PDBx:U13>
         <PDBx:U22>0.4133</PDBx:U22>
         <PDBx:U23>-0.0461</PDBx:U23>
         <PDBx:U33>0.3557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1991">
         <PDBx:U11>0.2663</PDBx:U11>
         <PDBx:U12>-0.0778</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.3233</PDBx:U22>
         <PDBx:U23>-0.0342</PDBx:U23>
         <PDBx:U33>0.2516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1992">
         <PDBx:U11>0.2842</PDBx:U11>
         <PDBx:U12>-0.0734</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.3506</PDBx:U22>
         <PDBx:U23>-0.0311</PDBx:U23>
         <PDBx:U33>0.2792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1993">
         <PDBx:U11>0.3916</PDBx:U11>
         <PDBx:U12>-0.0877</PDBx:U12>
         <PDBx:U13>0.0268</PDBx:U13>
         <PDBx:U22>0.4385</PDBx:U22>
         <PDBx:U23>-0.0497</PDBx:U23>
         <PDBx:U33>0.3658</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1994">
         <PDBx:U11>0.3932</PDBx:U11>
         <PDBx:U12>-0.0863</PDBx:U12>
         <PDBx:U13>0.0301</PDBx:U13>
         <PDBx:U22>0.4435</PDBx:U22>
         <PDBx:U23>-0.0533</PDBx:U23>
         <PDBx:U33>0.3747</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1995">
         <PDBx:U11>0.3799</PDBx:U11>
         <PDBx:U12>-0.0732</PDBx:U12>
         <PDBx:U13>0.0305</PDBx:U13>
         <PDBx:U22>0.4269</PDBx:U22>
         <PDBx:U23>-0.0569</PDBx:U23>
         <PDBx:U33>0.3835</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>325</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>25</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1996">
         <PDBx:U11>0.2648</PDBx:U11>
         <PDBx:U12>-0.0863</PDBx:U12>
         <PDBx:U13>0.0041</PDBx:U13>
         <PDBx:U22>0.3211</PDBx:U22>
         <PDBx:U23>-0.0268</PDBx:U23>
         <PDBx:U33>0.2362</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1997">
         <PDBx:U11>0.3684</PDBx:U11>
         <PDBx:U12>-0.0769</PDBx:U12>
         <PDBx:U13>-0.0063</PDBx:U13>
         <PDBx:U22>0.4348</PDBx:U22>
         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.3370</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1998">
         <PDBx:U11>0.3076</PDBx:U11>
         <PDBx:U12>-0.0904</PDBx:U12>
         <PDBx:U13>-0.0143</PDBx:U13>
         <PDBx:U22>0.3945</PDBx:U22>
         <PDBx:U23>0.0004</PDBx:U23>
         <PDBx:U33>0.2605</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="1999">
         <PDBx:U11>0.3667</PDBx:U11>
         <PDBx:U12>-0.1021</PDBx:U12>
         <PDBx:U13>-0.0137</PDBx:U13>
         <PDBx:U22>0.4459</PDBx:U22>
         <PDBx:U23>0.0036</PDBx:U23>
         <PDBx:U33>0.2940</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2000">
         <PDBx:U11>0.4505</PDBx:U11>
         <PDBx:U12>-0.0652</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.4953</PDBx:U22>
         <PDBx:U23>0.0047</PDBx:U23>
         <PDBx:U33>0.4091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2001">
         <PDBx:U11>0.4834</PDBx:U11>
         <PDBx:U12>-0.0548</PDBx:U12>
         <PDBx:U13>0.0036</PDBx:U13>
         <PDBx:U22>0.5149</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.4568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2002">
         <PDBx:U11>0.4013</PDBx:U11>
         <PDBx:U12>-0.0510</PDBx:U12>
         <PDBx:U13>-0.0131</PDBx:U13>
         <PDBx:U22>0.4567</PDBx:U22>
         <PDBx:U23>0.0283</PDBx:U23>
         <PDBx:U33>0.3594</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2003">
         <PDBx:U11>0.5268</PDBx:U11>
         <PDBx:U12>-0.0476</PDBx:U12>
         <PDBx:U13>0.0124</PDBx:U13>
         <PDBx:U22>0.5321</PDBx:U22>
         <PDBx:U23>0.0021</PDBx:U23>
         <PDBx:U33>0.4898</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>326</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>26</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2004">
         <PDBx:U11>0.2609</PDBx:U11>
         <PDBx:U12>-0.0911</PDBx:U12>
         <PDBx:U13>-0.0210</PDBx:U13>
         <PDBx:U22>0.3751</PDBx:U22>
         <PDBx:U23>0.0020</PDBx:U23>
         <PDBx:U33>0.2269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2005">
         <PDBx:U11>0.3129</PDBx:U11>
         <PDBx:U12>-0.1038</PDBx:U12>
         <PDBx:U13>-0.0260</PDBx:U13>
         <PDBx:U22>0.4501</PDBx:U22>
         <PDBx:U23>0.0056</PDBx:U23>
         <PDBx:U33>0.2669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2006">
         <PDBx:U11>0.3405</PDBx:U11>
         <PDBx:U12>-0.0947</PDBx:U12>
         <PDBx:U13>-0.0440</PDBx:U13>
         <PDBx:U22>0.5027</PDBx:U22>
         <PDBx:U23>0.0294</PDBx:U23>
         <PDBx:U33>0.2883</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2007">
         <PDBx:U11>0.2870</PDBx:U11>
         <PDBx:U12>-0.0721</PDBx:U12>
         <PDBx:U13>-0.0480</PDBx:U13>
         <PDBx:U22>0.4458</PDBx:U22>
         <PDBx:U23>0.0439</PDBx:U23>
         <PDBx:U33>0.2480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2008">
         <PDBx:U11>0.3018</PDBx:U11>
         <PDBx:U12>-0.1039</PDBx:U12>
         <PDBx:U13>-0.0184</PDBx:U13>
         <PDBx:U22>0.4473</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.2698</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2009">
         <PDBx:U11>0.2466</PDBx:U11>
         <PDBx:U12>-0.1016</PDBx:U12>
         <PDBx:U13>-0.0021</PDBx:U13>
         <PDBx:U22>0.3635</PDBx:U22>
         <PDBx:U23>-0.0220</PDBx:U23>
         <PDBx:U33>0.2184</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2010">
         <PDBx:U11>0.2556</PDBx:U11>
         <PDBx:U12>-0.1047</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.3779</PDBx:U22>
         <PDBx:U23>-0.0305</PDBx:U23>
         <PDBx:U33>0.2326</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2011">
         <PDBx:U11>0.2114</PDBx:U11>
         <PDBx:U12>-0.1109</PDBx:U12>
         <PDBx:U13>0.0083</PDBx:U13>
         <PDBx:U22>0.3111</PDBx:U22>
         <PDBx:U23>-0.0308</PDBx:U23>
         <PDBx:U33>0.1659</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>327</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>27</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2012">
         <PDBx:U11>0.3385</PDBx:U11>
         <PDBx:U12>-0.1060</PDBx:U12>
         <PDBx:U13>-0.0482</PDBx:U13>
         <PDBx:U22>0.5165</PDBx:U22>
         <PDBx:U23>0.0339</PDBx:U23>
         <PDBx:U33>0.2711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2013">
         <PDBx:U11>0.2766</PDBx:U11>
         <PDBx:U12>-0.0925</PDBx:U12>
         <PDBx:U13>-0.0642</PDBx:U13>
         <PDBx:U22>0.4779</PDBx:U22>
         <PDBx:U23>0.0570</PDBx:U23>
         <PDBx:U33>0.2063</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2014">
         <PDBx:U11>0.3897</PDBx:U11>
         <PDBx:U12>-0.0916</PDBx:U12>
         <PDBx:U13>-0.0695</PDBx:U13>
         <PDBx:U22>0.6317</PDBx:U22>
         <PDBx:U23>0.0548</PDBx:U23>
         <PDBx:U33>0.3434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2015">
         <PDBx:U11>0.3702</PDBx:U11>
         <PDBx:U12>-0.1093</PDBx:U12>
         <PDBx:U13>-0.0591</PDBx:U13>
         <PDBx:U22>0.6189</PDBx:U22>
         <PDBx:U23>0.0358</PDBx:U23>
         <PDBx:U33>0.3275</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2016">
         <PDBx:U11>0.3382</PDBx:U11>
         <PDBx:U12>-0.1047</PDBx:U12>
         <PDBx:U13>-0.0675</PDBx:U13>
         <PDBx:U22>0.5325</PDBx:U22>
         <PDBx:U23>0.0638</PDBx:U23>
         <PDBx:U33>0.2334</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2017">
         <PDBx:U11>0.4184</PDBx:U11>
         <PDBx:U12>-0.0986</PDBx:U12>
         <PDBx:U13>-0.0625</PDBx:U13>
         <PDBx:U22>0.5691</PDBx:U22>
         <PDBx:U23>0.0738</PDBx:U23>
         <PDBx:U33>0.2844</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2018">
         <PDBx:U11>0.4194</PDBx:U11>
         <PDBx:U12>-0.0752</PDBx:U12>
         <PDBx:U13>-0.0699</PDBx:U13>
         <PDBx:U22>0.5582</PDBx:U22>
         <PDBx:U23>0.1013</PDBx:U23>
         <PDBx:U33>0.2711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2019">
         <PDBx:U11>0.4387</PDBx:U11>
         <PDBx:U12>-0.1154</PDBx:U12>
         <PDBx:U13>-0.0461</PDBx:U13>
         <PDBx:U22>0.5559</PDBx:U22>
         <PDBx:U23>0.0548</PDBx:U23>
         <PDBx:U33>0.2918</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2020">
         <PDBx:U11>0.5089</PDBx:U11>
         <PDBx:U12>-0.0709</PDBx:U12>
         <PDBx:U13>-0.0582</PDBx:U13>
         <PDBx:U22>0.5984</PDBx:U22>
         <PDBx:U23>0.1100</PDBx:U23>
         <PDBx:U33>0.3303</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2021">
         <PDBx:U11>0.5010</PDBx:U11>
         <PDBx:U12>-0.1129</PDBx:U12>
         <PDBx:U13>-0.0358</PDBx:U13>
         <PDBx:U22>0.5752</PDBx:U22>
         <PDBx:U23>0.0605</PDBx:U23>
         <PDBx:U33>0.3269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2022">
         <PDBx:U11>0.5912</PDBx:U11>
         <PDBx:U12>-0.0918</PDBx:U12>
         <PDBx:U13>-0.0405</PDBx:U13>
         <PDBx:U22>0.6491</PDBx:U22>
         <PDBx:U23>0.0884</PDBx:U23>
         <PDBx:U33>0.3994</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2023">
         <PDBx:U11>0.6998</PDBx:U11>
         <PDBx:U12>-0.0908</PDBx:U12>
         <PDBx:U13>-0.0240</PDBx:U13>
         <PDBx:U22>0.7074</PDBx:U22>
         <PDBx:U23>0.0926</PDBx:U23>
         <PDBx:U33>0.4807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>328</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>28</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2024">
         <PDBx:U11>0.3915</PDBx:U11>
         <PDBx:U12>-0.0697</PDBx:U12>
         <PDBx:U13>-0.0824</PDBx:U13>
         <PDBx:U22>0.6561</PDBx:U22>
         <PDBx:U23>0.0737</PDBx:U23>
         <PDBx:U33>0.3604</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2025">
         <PDBx:U11>0.4262</PDBx:U11>
         <PDBx:U12>-0.0701</PDBx:U12>
         <PDBx:U13>-0.0889</PDBx:U13>
         <PDBx:U22>0.7339</PDBx:U22>
         <PDBx:U23>0.0717</PDBx:U23>
         <PDBx:U33>0.4154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2026">
         <PDBx:U11>0.5005</PDBx:U11>
         <PDBx:U12>-0.0794</PDBx:U12>
         <PDBx:U13>-0.1011</PDBx:U13>
         <PDBx:U22>0.8343</PDBx:U22>
         <PDBx:U23>0.0802</PDBx:U23>
         <PDBx:U33>0.4691</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2027">
         <PDBx:U11>0.4678</PDBx:U11>
         <PDBx:U12>-0.0803</PDBx:U12>
         <PDBx:U13>-0.1049</PDBx:U13>
         <PDBx:U22>0.7815</PDBx:U22>
         <PDBx:U23>0.0911</PDBx:U23>
         <PDBx:U33>0.4073</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2028">
         <PDBx:U11>0.3418</PDBx:U11>
         <PDBx:U12>-0.0412</PDBx:U12>
         <PDBx:U13>-0.0953</PDBx:U13>
         <PDBx:U22>0.6630</PDBx:U22>
         <PDBx:U23>0.0859</PDBx:U23>
         <PDBx:U33>0.3624</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2029">
         <PDBx:U11>0.3575</PDBx:U11>
         <PDBx:U12>-0.0191</PDBx:U12>
         <PDBx:U13>-0.1066</PDBx:U13>
         <PDBx:U22>0.6756</PDBx:U22>
         <PDBx:U23>0.1116</PDBx:U23>
         <PDBx:U33>0.3705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>329</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>29</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2030">
         <PDBx:U11>0.5668</PDBx:U11>
         <PDBx:U12>-0.0875</PDBx:U12>
         <PDBx:U13>-0.1069</PDBx:U13>
         <PDBx:U22>0.9445</PDBx:U22>
         <PDBx:U23>0.0746</PDBx:U23>
         <PDBx:U33>0.5478</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2031">
         <PDBx:U11>0.6440</PDBx:U11>
         <PDBx:U12>-0.0961</PDBx:U12>
         <PDBx:U13>-0.1212</PDBx:U13>
         <PDBx:U22>1.0554</PDBx:U22>
         <PDBx:U23>0.0832</PDBx:U23>
         <PDBx:U33>0.6074</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2032">
         <PDBx:U11>0.6276</PDBx:U11>
         <PDBx:U12>-0.0665</PDBx:U12>
         <PDBx:U13>-0.1411</PDBx:U13>
         <PDBx:U22>1.0692</PDBx:U22>
         <PDBx:U23>0.1069</PDBx:U23>
         <PDBx:U33>0.6090</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2033">
         <PDBx:U11>0.6860</PDBx:U11>
         <PDBx:U12>-0.0698</PDBx:U12>
         <PDBx:U13>-0.1547</PDBx:U13>
         <PDBx:U22>1.1763</PDBx:U22>
         <PDBx:U23>0.1097</PDBx:U23>
         <PDBx:U33>0.6730</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2034">
         <PDBx:U11>0.7402</PDBx:U11>
         <PDBx:U12>-0.1266</PDBx:U12>
         <PDBx:U13>-0.1139</PDBx:U13>
         <PDBx:U22>1.1839</PDBx:U22>
         <PDBx:U23>0.0613</PDBx:U23>
         <PDBx:U33>0.7022</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2035">
         <PDBx:U11>0.8148</PDBx:U11>
         <PDBx:U12>-0.1556</PDBx:U12>
         <PDBx:U13>-0.0932</PDBx:U13>
         <PDBx:U22>1.2263</PDBx:U22>
         <PDBx:U23>0.0417</PDBx:U23>
         <PDBx:U33>0.7522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2036">
         <PDBx:U11>0.8706</PDBx:U11>
         <PDBx:U12>-0.1758</PDBx:U12>
         <PDBx:U13>-0.0736</PDBx:U13>
         <PDBx:U22>1.2876</PDBx:U22>
         <PDBx:U23>0.0162</PDBx:U23>
         <PDBx:U33>0.8154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2037">
         <PDBx:U11>0.8824</PDBx:U11>
         <PDBx:U12>-0.1846</PDBx:U12>
         <PDBx:U13>-0.0778</PDBx:U13>
         <PDBx:U22>1.3436</PDBx:U22>
         <PDBx:U23>0.0102</PDBx:U23>
         <PDBx:U33>0.8358</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2038">
         <PDBx:U11>0.8722</PDBx:U11>
         <PDBx:U12>-0.1814</PDBx:U12>
         <PDBx:U13>-0.0534</PDBx:U13>
         <PDBx:U22>1.2477</PDBx:U22>
         <PDBx:U23>0.0019</PDBx:U23>
         <PDBx:U33>0.8124</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>330</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>30</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2039">
         <PDBx:U11>0.5258</PDBx:U11>
         <PDBx:U12>-0.0373</PDBx:U12>
         <PDBx:U13>-0.1412</PDBx:U13>
         <PDBx:U22>0.9377</PDBx:U22>
         <PDBx:U23>0.1235</PDBx:U23>
         <PDBx:U33>0.5168</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2040">
         <PDBx:U11>0.5138</PDBx:U11>
         <PDBx:U12>-0.0045</PDBx:U12>
         <PDBx:U13>-0.1551</PDBx:U13>
         <PDBx:U22>0.9432</PDBx:U22>
         <PDBx:U23>0.1472</PDBx:U23>
         <PDBx:U33>0.5247</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2041">
         <PDBx:U11>0.5533</PDBx:U11>
         <PDBx:U12>0.0030</PDBx:U12>
         <PDBx:U13>-0.1730</PDBx:U13>
         <PDBx:U22>0.9920</PDBx:U22>
         <PDBx:U23>0.1695</PDBx:U23>
         <PDBx:U33>0.5344</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2042">
         <PDBx:U11>0.5439</PDBx:U11>
         <PDBx:U12>0.0049</PDBx:U12>
         <PDBx:U13>-0.1706</PDBx:U13>
         <PDBx:U22>0.9394</PDBx:U22>
         <PDBx:U23>0.1807</PDBx:U23>
         <PDBx:U33>0.4875</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2043">
         <PDBx:U11>0.4827</PDBx:U11>
         <PDBx:U12>0.0226</PDBx:U12>
         <PDBx:U13>-0.1444</PDBx:U13>
         <PDBx:U22>0.8672</PDBx:U22>
         <PDBx:U23>0.1587</PDBx:U23>
         <PDBx:U33>0.5060</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2044">
         <PDBx:U11>0.5179</PDBx:U11>
         <PDBx:U12>0.0582</PDBx:U12>
         <PDBx:U13>-0.1535</PDBx:U13>
         <PDBx:U22>0.9052</PDBx:U22>
         <PDBx:U23>0.1854</PDBx:U23>
         <PDBx:U33>0.5564</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2045">
         <PDBx:U11>0.5474</PDBx:U11>
         <PDBx:U12>0.0709</PDBx:U12>
         <PDBx:U13>-0.1646</PDBx:U13>
         <PDBx:U22>0.9851</PDBx:U22>
         <PDBx:U23>0.1883</PDBx:U23>
         <PDBx:U33>0.6237</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2046">
         <PDBx:U11>0.5803</PDBx:U11>
         <PDBx:U12>0.0789</PDBx:U12>
         <PDBx:U13>-0.1487</PDBx:U13>
         <PDBx:U22>0.9169</PDBx:U22>
         <PDBx:U23>0.2069</PDBx:U23>
         <PDBx:U33>0.5957</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2047">
         <PDBx:U11>0.6085</PDBx:U11>
         <PDBx:U12>0.1050</PDBx:U12>
         <PDBx:U13>-0.1718</PDBx:U13>
         <PDBx:U22>1.0486</PDBx:U22>
         <PDBx:U23>0.2128</PDBx:U23>
         <PDBx:U33>0.7022</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2048">
         <PDBx:U11>0.6544</PDBx:U11>
         <PDBx:U12>0.1122</PDBx:U12>
         <PDBx:U13>-0.1534</PDBx:U13>
         <PDBx:U22>0.9869</PDBx:U22>
         <PDBx:U23>0.2316</PDBx:U23>
         <PDBx:U33>0.6834</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2049">
         <PDBx:U11>0.6716</PDBx:U11>
         <PDBx:U12>0.1261</PDBx:U12>
         <PDBx:U13>-0.1655</PDBx:U13>
         <PDBx:U22>1.0573</PDBx:U22>
         <PDBx:U23>0.2349</PDBx:U23>
         <PDBx:U33>0.7413</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2050">
         <PDBx:U11>0.7330</PDBx:U11>
         <PDBx:U12>0.1606</PDBx:U12>
         <PDBx:U13>-0.1694</PDBx:U13>
         <PDBx:U22>1.1155</PDBx:U22>
         <PDBx:U23>0.2596</PDBx:U23>
         <PDBx:U33>0.8197</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>331</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>31</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2051">
         <PDBx:U11>0.6368</PDBx:U11>
         <PDBx:U12>0.0067</PDBx:U12>
         <PDBx:U13>-0.1909</PDBx:U13>
         <PDBx:U22>1.1316</PDBx:U22>
         <PDBx:U23>0.1754</PDBx:U23>
         <PDBx:U33>0.6326</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2052">
         <PDBx:U11>0.7025</PDBx:U11>
         <PDBx:U12>0.0180</PDBx:U12>
         <PDBx:U13>-0.2116</PDBx:U13>
         <PDBx:U22>1.2120</PDBx:U22>
         <PDBx:U23>0.1995</PDBx:U23>
         <PDBx:U33>0.6718</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2053">
         <PDBx:U11>0.7303</PDBx:U11>
         <PDBx:U12>0.0609</PDBx:U12>
         <PDBx:U13>-0.2207</PDBx:U13>
         <PDBx:U22>1.2361</PDBx:U22>
         <PDBx:U23>0.2277</PDBx:U23>
         <PDBx:U33>0.7217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2054">
         <PDBx:U11>0.7168</PDBx:U11>
         <PDBx:U12>0.0747</PDBx:U12>
         <PDBx:U13>-0.2296</PDBx:U13>
         <PDBx:U22>1.2694</PDBx:U22>
         <PDBx:U23>0.2290</PDBx:U23>
         <PDBx:U33>0.7511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2055">
         <PDBx:U11>0.7751</PDBx:U11>
         <PDBx:U12>-0.0038</PDBx:U12>
         <PDBx:U13>-0.2273</PDBx:U13>
         <PDBx:U22>1.3531</PDBx:U22>
         <PDBx:U23>0.1902</PDBx:U23>
         <PDBx:U33>0.7461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>332</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>32</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2056">
         <PDBx:U11>0.7919</PDBx:U11>
         <PDBx:U12>0.0814</PDBx:U12>
         <PDBx:U13>-0.2161</PDBx:U13>
         <PDBx:U22>1.2387</PDBx:U22>
         <PDBx:U23>0.2496</PDBx:U23>
         <PDBx:U33>0.7539</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2057">
         <PDBx:U11>0.8471</PDBx:U11>
         <PDBx:U12>0.1226</PDBx:U12>
         <PDBx:U13>-0.2184</PDBx:U13>
         <PDBx:U22>1.2756</PDBx:U22>
         <PDBx:U23>0.2774</PDBx:U23>
         <PDBx:U33>0.8264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2058">
         <PDBx:U11>0.8983</PDBx:U11>
         <PDBx:U12>0.1420</PDBx:U12>
         <PDBx:U13>-0.2451</PDBx:U13>
         <PDBx:U22>1.3837</PDBx:U22>
         <PDBx:U23>0.2977</PDBx:U23>
         <PDBx:U33>0.8919</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2059">
         <PDBx:U11>0.9073</PDBx:U11>
         <PDBx:U12>0.1769</PDBx:U12>
         <PDBx:U13>-0.2499</PDBx:U13>
         <PDBx:U22>1.3752</PDBx:U22>
         <PDBx:U23>0.3260</PDBx:U23>
         <PDBx:U33>0.9050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2060">
         <PDBx:U11>0.9237</PDBx:U11>
         <PDBx:U12>0.1298</PDBx:U12>
         <PDBx:U13>-0.2087</PDBx:U13>
         <PDBx:U22>1.2765</PDBx:U22>
         <PDBx:U23>0.2950</PDBx:U23>
         <PDBx:U33>0.8499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2061">
         <PDBx:U11>0.8864</PDBx:U11>
         <PDBx:U12>0.0954</PDBx:U12>
         <PDBx:U13>-0.1936</PDBx:U13>
         <PDBx:U22>1.2123</PDBx:U22>
         <PDBx:U23>0.2699</PDBx:U23>
         <PDBx:U33>0.7858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2062">
         <PDBx:U11>0.8330</PDBx:U11>
         <PDBx:U12>0.0647</PDBx:U12>
         <PDBx:U13>-0.2045</PDBx:U13>
         <PDBx:U22>1.2223</PDBx:U22>
         <PDBx:U23>0.2474</PDBx:U23>
         <PDBx:U33>0.7426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>333</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>33</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2063">
         <PDBx:U11>0.9090</PDBx:U11>
         <PDBx:U12>0.1192</PDBx:U12>
         <PDBx:U13>-0.2612</PDBx:U13>
         <PDBx:U22>1.4616</PDBx:U22>
         <PDBx:U23>0.2833</PDBx:U23>
         <PDBx:U33>0.9104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2064">
         <PDBx:U11>0.9627</PDBx:U11>
         <PDBx:U12>0.1344</PDBx:U12>
         <PDBx:U13>-0.2890</PDBx:U13>
         <PDBx:U22>1.5813</PDBx:U22>
         <PDBx:U23>0.2996</PDBx:U23>
         <PDBx:U33>0.9810</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2065">
         <PDBx:U11>0.9745</PDBx:U11>
         <PDBx:U12>0.1125</PDBx:U12>
         <PDBx:U13>-0.2946</PDBx:U13>
         <PDBx:U22>1.6689</PDBx:U22>
         <PDBx:U23>0.2730</PDBx:U23>
         <PDBx:U33>1.0350</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2066">
         <PDBx:U11>1.0157</PDBx:U11>
         <PDBx:U12>0.0837</PDBx:U12>
         <PDBx:U13>-0.3063</PDBx:U13>
         <PDBx:U22>1.7550</PDBx:U22>
         <PDBx:U23>0.2611</PDBx:U23>
         <PDBx:U33>1.0581</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2067">
         <PDBx:U11>0.9968</PDBx:U11>
         <PDBx:U12>0.1265</PDBx:U12>
         <PDBx:U13>-0.3094</PDBx:U13>
         <PDBx:U22>1.6208</PDBx:U22>
         <PDBx:U23>0.3164</PDBx:U23>
         <PDBx:U33>0.9580</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2068">
         <PDBx:U11>0.9593</PDBx:U11>
         <PDBx:U12>0.0819</PDBx:U12>
         <PDBx:U13>-0.3093</PDBx:U13>
         <PDBx:U22>1.6154</PDBx:U22>
         <PDBx:U23>0.2888</PDBx:U23>
         <PDBx:U33>0.9014</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2069">
         <PDBx:U11>0.9965</PDBx:U11>
         <PDBx:U12>0.1369</PDBx:U12>
         <PDBx:U13>-0.2984</PDBx:U13>
         <PDBx:U22>1.5343</PDBx:U22>
         <PDBx:U23>0.3355</PDBx:U23>
         <PDBx:U33>0.9029</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>334</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>34</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2070">
         <PDBx:U11>0.9519</PDBx:U11>
         <PDBx:U12>0.1241</PDBx:U12>
         <PDBx:U13>-0.2839</PDBx:U13>
         <PDBx:U22>1.6579</PDBx:U22>
         <PDBx:U23>0.2624</PDBx:U23>
         <PDBx:U33>1.0664</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2071">
         <PDBx:U11>0.9308</PDBx:U11>
         <PDBx:U12>0.1045</PDBx:U12>
         <PDBx:U13>-0.2866</PDBx:U13>
         <PDBx:U22>1.7035</PDBx:U22>
         <PDBx:U23>0.2365</PDBx:U23>
         <PDBx:U33>1.0864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2072">
         <PDBx:U11>0.9493</PDBx:U11>
         <PDBx:U12>0.1361</PDBx:U12>
         <PDBx:U13>-0.2996</PDBx:U13>
         <PDBx:U22>1.7723</PDBx:U22>
         <PDBx:U23>0.2476</PDBx:U23>
         <PDBx:U33>1.1637</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2073">
         <PDBx:U11>0.9720</PDBx:U11>
         <PDBx:U12>0.1331</PDBx:U12>
         <PDBx:U13>-0.3217</PDBx:U13>
         <PDBx:U22>1.8686</PDBx:U22>
         <PDBx:U23>0.2478</PDBx:U23>
         <PDBx:U33>1.2045</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2074">
         <PDBx:U11>0.8148</PDBx:U11>
         <PDBx:U12>0.0784</PDBx:U12>
         <PDBx:U13>-0.2589</PDBx:U13>
         <PDBx:U22>1.5581</PDBx:U22>
         <PDBx:U23>0.2043</PDBx:U23>
         <PDBx:U33>0.9790</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2075">
         <PDBx:U11>0.7799</PDBx:U11>
         <PDBx:U12>0.0405</PDBx:U12>
         <PDBx:U13>-0.2477</PDBx:U13>
         <PDBx:U22>1.4955</PDBx:U22>
         <PDBx:U23>0.1866</PDBx:U23>
         <PDBx:U33>0.8961</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2076">
         <PDBx:U11>0.7613</PDBx:U11>
         <PDBx:U12>0.0062</PDBx:U12>
         <PDBx:U13>-0.2565</PDBx:U13>
         <PDBx:U22>1.5383</PDBx:U22>
         <PDBx:U23>0.1676</PDBx:U23>
         <PDBx:U33>0.8707</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2077">
         <PDBx:U11>0.6951</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>-0.2474</PDBx:U13>
         <PDBx:U22>1.5097</PDBx:U22>
         <PDBx:U23>0.1415</PDBx:U23>
         <PDBx:U33>0.8457</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2078">
         <PDBx:U11>0.6360</PDBx:U11>
         <PDBx:U12>-0.0390</PDBx:U12>
         <PDBx:U13>-0.2244</PDBx:U13>
         <PDBx:U22>1.4327</PDBx:U22>
         <PDBx:U23>0.1118</PDBx:U23>
         <PDBx:U33>0.7807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2079">
         <PDBx:U11>0.5839</PDBx:U11>
         <PDBx:U12>-0.0500</PDBx:U12>
         <PDBx:U13>-0.2158</PDBx:U13>
         <PDBx:U22>1.4117</PDBx:U22>
         <PDBx:U23>0.0896</PDBx:U23>
         <PDBx:U33>0.7634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2080">
         <PDBx:U11>0.6471</PDBx:U11>
         <PDBx:U12>-0.0589</PDBx:U12>
         <PDBx:U13>-0.2091</PDBx:U13>
         <PDBx:U22>1.3931</PDBx:U22>
         <PDBx:U23>0.1042</PDBx:U23>
         <PDBx:U33>0.7514</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>335</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>35</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2081">
         <PDBx:U11>0.9340</PDBx:U11>
         <PDBx:U12>0.1657</PDBx:U12>
         <PDBx:U13>-0.2850</PDBx:U13>
         <PDBx:U22>1.7197</PDBx:U22>
         <PDBx:U23>0.2556</PDBx:U23>
         <PDBx:U33>1.1800</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2082">
         <PDBx:U11>0.8718</PDBx:U11>
         <PDBx:U12>0.1692</PDBx:U12>
         <PDBx:U13>-0.2576</PDBx:U13>
         <PDBx:U22>1.5763</PDBx:U22>
         <PDBx:U23>0.2532</PDBx:U23>
         <PDBx:U33>1.1023</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2083">
         <PDBx:U11>0.7983</PDBx:U11>
         <PDBx:U12>0.1468</PDBx:U12>
         <PDBx:U13>-0.2354</PDBx:U13>
         <PDBx:U22>1.4960</PDBx:U22>
         <PDBx:U23>0.2202</PDBx:U23>
         <PDBx:U33>1.0535</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2084">
         <PDBx:U11>0.7975</PDBx:U11>
         <PDBx:U12>0.1273</PDBx:U12>
         <PDBx:U13>-0.2177</PDBx:U13>
         <PDBx:U22>1.4457</PDBx:U22>
         <PDBx:U23>0.2074</PDBx:U23>
         <PDBx:U33>1.0228</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2085">
         <PDBx:U11>0.9061</PDBx:U11>
         <PDBx:U12>0.2143</PDBx:U12>
         <PDBx:U13>-0.2548</PDBx:U13>
         <PDBx:U22>1.5870</PDBx:U22>
         <PDBx:U23>0.2797</PDBx:U23>
         <PDBx:U33>1.1636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2086">
         <PDBx:U11>0.9399</PDBx:U11>
         <PDBx:U12>0.2285</PDBx:U12>
         <PDBx:U13>-0.2717</PDBx:U13>
         <PDBx:U22>1.6967</PDBx:U22>
         <PDBx:U23>0.2793</PDBx:U23>
         <PDBx:U33>1.2544</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2087">
         <PDBx:U11>0.9670</PDBx:U11>
         <PDBx:U12>0.2024</PDBx:U12>
         <PDBx:U13>-0.2967</PDBx:U13>
         <PDBx:U22>1.7919</PDBx:U22>
         <PDBx:U23>0.2718</PDBx:U23>
         <PDBx:U33>1.2671</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>336</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>36</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2088">
         <PDBx:U11>0.7118</PDBx:U11>
         <PDBx:U12>0.1494</PDBx:U12>
         <PDBx:U13>-0.2365</PDBx:U13>
         <PDBx:U22>1.4582</PDBx:U22>
         <PDBx:U23>0.2065</PDBx:U23>
         <PDBx:U33>1.0205</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2089">
         <PDBx:U11>0.6302</PDBx:U11>
         <PDBx:U12>0.1305</PDBx:U12>
         <PDBx:U13>-0.2142</PDBx:U13>
         <PDBx:U22>1.3647</PDBx:U22>
         <PDBx:U23>0.1767</PDBx:U23>
         <PDBx:U33>0.9616</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2090">
         <PDBx:U11>0.5606</PDBx:U11>
         <PDBx:U12>0.1217</PDBx:U12>
         <PDBx:U13>-0.2182</PDBx:U13>
         <PDBx:U22>1.3617</PDBx:U22>
         <PDBx:U23>0.1566</PDBx:U23>
         <PDBx:U33>0.9448</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2091">
         <PDBx:U11>0.5849</PDBx:U11>
         <PDBx:U12>0.1377</PDBx:U12>
         <PDBx:U13>-0.2383</PDBx:U13>
         <PDBx:U22>1.4454</PDBx:U22>
         <PDBx:U23>0.1673</PDBx:U23>
         <PDBx:U33>1.0013</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2092">
         <PDBx:U11>0.6155</PDBx:U11>
         <PDBx:U12>0.1517</PDBx:U12>
         <PDBx:U13>-0.1913</PDBx:U13>
         <PDBx:U22>1.2851</PDBx:U22>
         <PDBx:U23>0.1816</PDBx:U23>
         <PDBx:U33>0.9554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2093">
         <PDBx:U11>0.5634</PDBx:U11>
         <PDBx:U12>0.1360</PDBx:U12>
         <PDBx:U13>-0.1746</PDBx:U13>
         <PDBx:U22>1.1665</PDBx:U22>
         <PDBx:U23>0.1770</PDBx:U23>
         <PDBx:U33>0.8558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2094">
         <PDBx:U11>0.5191</PDBx:U11>
         <PDBx:U12>0.0997</PDBx:U12>
         <PDBx:U13>-0.1710</PDBx:U13>
         <PDBx:U22>1.1227</PDBx:U22>
         <PDBx:U23>0.1551</PDBx:U23>
         <PDBx:U33>0.7846</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2095">
         <PDBx:U11>0.5389</PDBx:U11>
         <PDBx:U12>0.1568</PDBx:U12>
         <PDBx:U13>-0.1612</PDBx:U13>
         <PDBx:U22>1.0795</PDBx:U22>
         <PDBx:U23>0.1935</PDBx:U23>
         <PDBx:U33>0.8148</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2096">
         <PDBx:U11>0.4229</PDBx:U11>
         <PDBx:U12>0.0862</PDBx:U12>
         <PDBx:U13>-0.1569</PDBx:U13>
         <PDBx:U22>0.9707</PDBx:U22>
         <PDBx:U23>0.1504</PDBx:U23>
         <PDBx:U33>0.6499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2097">
         <PDBx:U11>0.4771</PDBx:U11>
         <PDBx:U12>0.1413</PDBx:U12>
         <PDBx:U13>-0.1470</PDBx:U13>
         <PDBx:U22>0.9628</PDBx:U22>
         <PDBx:U23>0.1879</PDBx:U23>
         <PDBx:U33>0.7133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2098">
         <PDBx:U11>0.4419</PDBx:U11>
         <PDBx:U12>0.1070</PDBx:U12>
         <PDBx:U13>-0.1463</PDBx:U13>
         <PDBx:U22>0.9337</PDBx:U22>
         <PDBx:U23>0.1667</PDBx:U23>
         <PDBx:U33>0.6556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>337</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>37</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2099">
         <PDBx:U11>0.5065</PDBx:U11>
         <PDBx:U12>0.0952</PDBx:U12>
         <PDBx:U13>-0.1985</PDBx:U13>
         <PDBx:U22>1.2964</PDBx:U22>
         <PDBx:U23>0.1274</PDBx:U23>
         <PDBx:U33>0.8977</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2100">
         <PDBx:U11>0.5339</PDBx:U11>
         <PDBx:U12>0.0823</PDBx:U12>
         <PDBx:U13>-0.1939</PDBx:U13>
         <PDBx:U22>1.3728</PDBx:U22>
         <PDBx:U23>0.1041</PDBx:U23>
         <PDBx:U33>0.9735</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2101">
         <PDBx:U11>0.5036</PDBx:U11>
         <PDBx:U12>0.0578</PDBx:U12>
         <PDBx:U13>-0.1660</PDBx:U13>
         <PDBx:U22>1.2959</PDBx:U22>
         <PDBx:U23>0.0786</PDBx:U23>
         <PDBx:U33>0.9329</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2102">
         <PDBx:U11>0.5274</PDBx:U11>
         <PDBx:U12>0.0407</PDBx:U12>
         <PDBx:U13>-0.1578</PDBx:U13>
         <PDBx:U22>1.2746</PDBx:U22>
         <PDBx:U23>0.0749</PDBx:U23>
         <PDBx:U33>0.9081</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2103">
         <PDBx:U11>0.5654</PDBx:U11>
         <PDBx:U12>0.0576</PDBx:U12>
         <PDBx:U13>-0.2114</PDBx:U13>
         <PDBx:U22>1.4745</PDBx:U22>
         <PDBx:U23>0.0941</PDBx:U23>
         <PDBx:U33>1.0015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2104">
         <PDBx:U11>0.4249</PDBx:U11>
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         <PDBx:U22>1.3122</PDBx:U22>
         <PDBx:U23>0.0826</PDBx:U23>
         <PDBx:U33>0.8049</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>338</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>38</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2105">
         <PDBx:U11>0.4798</PDBx:U11>
         <PDBx:U12>0.0566</PDBx:U12>
         <PDBx:U13>-0.1507</PDBx:U13>
         <PDBx:U22>1.2819</PDBx:U22>
         <PDBx:U23>0.0620</PDBx:U23>
         <PDBx:U33>0.9552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2106">
         <PDBx:U11>0.5029</PDBx:U11>
         <PDBx:U12>0.0341</PDBx:U12>
         <PDBx:U13>-0.1235</PDBx:U13>
         <PDBx:U22>1.2606</PDBx:U22>
         <PDBx:U23>0.0396</PDBx:U23>
         <PDBx:U33>0.9682</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2107">
         <PDBx:U11>0.5150</PDBx:U11>
         <PDBx:U12>0.0005</PDBx:U12>
         <PDBx:U13>-0.1202</PDBx:U13>
         <PDBx:U22>1.2565</PDBx:U22>
         <PDBx:U23>0.0264</PDBx:U23>
         <PDBx:U33>0.9260</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2652</PDBx:U11>
         <PDBx:U12>-0.0078</PDBx:U12>
         <PDBx:U13>-0.1056</PDBx:U13>
         <PDBx:U22>0.9484</PDBx:U22>
         <PDBx:U23>0.0224</PDBx:U23>
         <PDBx:U33>0.6416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.5350</PDBx:U11>
         <PDBx:U12>0.0241</PDBx:U12>
         <PDBx:U13>-0.1095</PDBx:U13>
         <PDBx:U22>1.3258</PDBx:U22>
         <PDBx:U23>0.0197</PDBx:U23>
         <PDBx:U33>1.0513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2110">
         <PDBx:U11>0.5568</PDBx:U11>
         <PDBx:U12>0.0396</PDBx:U12>
         <PDBx:U13>-0.0866</PDBx:U13>
         <PDBx:U22>1.3095</PDBx:U22>
         <PDBx:U23>0.0177</PDBx:U23>
         <PDBx:U33>1.1057</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2111">
         <PDBx:U11>0.6083</PDBx:U11>
         <PDBx:U12>0.0229</PDBx:U12>
         <PDBx:U13>-0.0667</PDBx:U13>
         <PDBx:U22>1.3852</PDBx:U22>
         <PDBx:U23>-0.0022</PDBx:U23>
         <PDBx:U33>1.1980</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2112">
         <PDBx:U11>0.5973</PDBx:U11>
         <PDBx:U12>-0.0092</PDBx:U12>
         <PDBx:U13>-0.0594</PDBx:U13>
         <PDBx:U22>1.3842</PDBx:U22>
         <PDBx:U23>-0.0211</PDBx:U23>
         <PDBx:U33>1.1638</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2113">
         <PDBx:U11>0.6645</PDBx:U11>
         <PDBx:U12>0.0415</PDBx:U12>
         <PDBx:U13>-0.0557</PDBx:U13>
         <PDBx:U22>1.4481</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>1.3066</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>339</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>39</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2114">
         <PDBx:U11>0.3190</PDBx:U11>
         <PDBx:U12>-0.0185</PDBx:U12>
         <PDBx:U13>-0.1332</PDBx:U13>
         <PDBx:U22>1.1140</PDBx:U22>
         <PDBx:U23>0.0190</PDBx:U23>
         <PDBx:U33>0.7237</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2115">
         <PDBx:U11>0.4249</PDBx:U11>
         <PDBx:U12>-0.0529</PDBx:U12>
         <PDBx:U13>-0.1265</PDBx:U13>
         <PDBx:U22>1.2098</PDBx:U22>
         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.7810</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2116">
         <PDBx:U11>0.3168</PDBx:U11>
         <PDBx:U12>-0.0511</PDBx:U12>
         <PDBx:U13>-0.1314</PDBx:U13>
         <PDBx:U22>1.0582</PDBx:U22>
         <PDBx:U23>0.0168</PDBx:U23>
         <PDBx:U33>0.6226</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2117">
         <PDBx:U11>0.3803</PDBx:U11>
         <PDBx:U12>-0.0709</PDBx:U12>
         <PDBx:U13>-0.1151</PDBx:U13>
         <PDBx:U22>1.0768</PDBx:U22>
         <PDBx:U23>0.0043</PDBx:U23>
         <PDBx:U33>0.6497</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2118">
         <PDBx:U11>0.3584</PDBx:U11>
         <PDBx:U12>-0.0732</PDBx:U12>
         <PDBx:U13>-0.1388</PDBx:U13>
         <PDBx:U22>1.2159</PDBx:U22>
         <PDBx:U23>-0.0090</PDBx:U23>
         <PDBx:U33>0.7197</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>340</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>40</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2119">
         <PDBx:U11>0.4634</PDBx:U11>
         <PDBx:U12>-0.0269</PDBx:U12>
         <PDBx:U13>-0.1525</PDBx:U13>
         <PDBx:U22>1.2171</PDBx:U22>
         <PDBx:U23>0.0432</PDBx:U23>
         <PDBx:U33>0.7673</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2120">
         <PDBx:U11>0.3407</PDBx:U11>
         <PDBx:U12>-0.0258</PDBx:U12>
         <PDBx:U13>-0.1568</PDBx:U13>
         <PDBx:U22>1.0556</PDBx:U22>
         <PDBx:U23>0.0580</PDBx:U23>
         <PDBx:U33>0.5975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2121">
         <PDBx:U11>0.3905</PDBx:U11>
         <PDBx:U12>-0.0144</PDBx:U12>
         <PDBx:U13>-0.1404</PDBx:U13>
         <PDBx:U22>1.0347</PDBx:U22>
         <PDBx:U23>0.0620</PDBx:U23>
         <PDBx:U33>0.6357</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2122">
         <PDBx:U11>0.3367</PDBx:U11>
         <PDBx:U12>-0.0306</PDBx:U12>
         <PDBx:U13>-0.1300</PDBx:U13>
         <PDBx:U22>0.9398</PDBx:U22>
         <PDBx:U23>0.0555</PDBx:U23>
         <PDBx:U33>0.5445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2123">
         <PDBx:U11>0.3818</PDBx:U11>
         <PDBx:U12>-0.0015</PDBx:U12>
         <PDBx:U13>-0.1822</PDBx:U13>
         <PDBx:U22>1.1242</PDBx:U22>
         <PDBx:U23>0.0871</PDBx:U23>
         <PDBx:U33>0.6372</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2124">
         <PDBx:U11>0.3814</PDBx:U11>
         <PDBx:U12>0.0357</PDBx:U12>
         <PDBx:U13>-0.1844</PDBx:U13>
         <PDBx:U22>1.1075</PDBx:U22>
         <PDBx:U23>0.1070</PDBx:U23>
         <PDBx:U33>0.6660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>341</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>41</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2125">
         <PDBx:U11>0.4130</PDBx:U11>
         <PDBx:U12>0.0132</PDBx:U12>
         <PDBx:U13>-0.1372</PDBx:U13>
         <PDBx:U22>1.0452</PDBx:U22>
         <PDBx:U23>0.0717</PDBx:U23>
         <PDBx:U33>0.6918</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2126">
         <PDBx:U11>0.3503</PDBx:U11>
         <PDBx:U12>0.0238</PDBx:U12>
         <PDBx:U13>-0.1205</PDBx:U13>
         <PDBx:U22>0.9208</PDBx:U22>
         <PDBx:U23>0.0740</PDBx:U23>
         <PDBx:U33>0.6214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2127">
         <PDBx:U11>0.3232</PDBx:U11>
         <PDBx:U12>-0.0033</PDBx:U12>
         <PDBx:U13>-0.1011</PDBx:U13>
         <PDBx:U22>0.8641</PDBx:U22>
         <PDBx:U23>0.0495</PDBx:U23>
         <PDBx:U33>0.5783</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2128">
         <PDBx:U11>0.2707</PDBx:U11>
         <PDBx:U12>-0.0097</PDBx:U12>
         <PDBx:U13>-0.0931</PDBx:U13>
         <PDBx:U22>0.7666</PDBx:U22>
         <PDBx:U23>0.0490</PDBx:U23>
         <PDBx:U33>0.4932</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2129">
         <PDBx:U11>0.3477</PDBx:U11>
         <PDBx:U12>0.0510</PDBx:U12>
         <PDBx:U13>-0.1141</PDBx:U13>
         <PDBx:U22>0.9166</PDBx:U22>
         <PDBx:U23>0.0798</PDBx:U23>
         <PDBx:U33>0.6632</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2130">
         <PDBx:U11>0.4278</PDBx:U11>
         <PDBx:U12>0.0576</PDBx:U12>
         <PDBx:U13>-0.0933</PDBx:U13>
         <PDBx:U22>0.9378</PDBx:U22>
         <PDBx:U23>0.0769</PDBx:U23>
         <PDBx:U33>0.7376</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2131">
         <PDBx:U11>0.7949</PDBx:U11>
         <PDBx:U12>0.0779</PDBx:U12>
         <PDBx:U13>-0.0941</PDBx:U13>
         <PDBx:U22>1.2529</PDBx:U22>
         <PDBx:U23>0.1024</PDBx:U23>
         <PDBx:U33>1.0684</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2132">
         <PDBx:U11>0.9129</PDBx:U11>
         <PDBx:U12>0.1165</PDBx:U12>
         <PDBx:U13>-0.0930</PDBx:U13>
         <PDBx:U22>1.3740</PDBx:U22>
         <PDBx:U23>0.1218</PDBx:U23>
         <PDBx:U33>1.2240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>342</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>42</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2133">
         <PDBx:U11>0.3274</PDBx:U11>
         <PDBx:U12>-0.0186</PDBx:U12>
         <PDBx:U13>-0.0928</PDBx:U13>
         <PDBx:U22>0.8937</PDBx:U22>
         <PDBx:U23>0.0298</PDBx:U23>
         <PDBx:U33>0.6061</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2134">
         <PDBx:U11>0.2805</PDBx:U11>
         <PDBx:U12>-0.0431</PDBx:U12>
         <PDBx:U13>-0.0720</PDBx:U13>
         <PDBx:U22>0.8171</PDBx:U22>
         <PDBx:U23>0.0071</PDBx:U23>
         <PDBx:U33>0.5440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2135">
         <PDBx:U11>0.2994</PDBx:U11>
         <PDBx:U12>-0.0683</PDBx:U12>
         <PDBx:U13>-0.0710</PDBx:U13>
         <PDBx:U22>0.8263</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.5185</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2136">
         <PDBx:U11>0.2853</PDBx:U11>
         <PDBx:U12>-0.0810</PDBx:U12>
         <PDBx:U13>-0.0551</PDBx:U13>
         <PDBx:U22>0.7676</PDBx:U22>
         <PDBx:U23>-0.0132</PDBx:U23>
         <PDBx:U33>0.4792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2137">
         <PDBx:U11>0.2863</PDBx:U11>
         <PDBx:U12>-0.0550</PDBx:U12>
         <PDBx:U13>-0.0617</PDBx:U13>
         <PDBx:U22>0.8534</PDBx:U22>
         <PDBx:U23>-0.0110</PDBx:U23>
         <PDBx:U33>0.5818</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2138">
         <PDBx:U11>0.3285</PDBx:U11>
         <PDBx:U12>-0.0347</PDBx:U12>
         <PDBx:U13>-0.0536</PDBx:U13>
         <PDBx:U22>0.8948</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.6688</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2139">
         <PDBx:U11>0.3924</PDBx:U11>
         <PDBx:U12>-0.0252</PDBx:U12>
         <PDBx:U13>-0.0328</PDBx:U13>
         <PDBx:U22>0.8873</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.7201</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2140">
         <PDBx:U11>0.1687</PDBx:U11>
         <PDBx:U12>-0.0579</PDBx:U12>
         <PDBx:U13>-0.0116</PDBx:U13>
         <PDBx:U22>0.6320</PDBx:U22>
         <PDBx:U23>-0.0284</PDBx:U23>
         <PDBx:U33>0.4617</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>343</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>43</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2141">
         <PDBx:U11>0.2718</PDBx:U11>
         <PDBx:U12>-0.0752</PDBx:U12>
         <PDBx:U13>-0.0869</PDBx:U13>
         <PDBx:U22>0.8403</PDBx:U22>
         <PDBx:U23>0.0024</PDBx:U23>
         <PDBx:U33>0.4816</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2142">
         <PDBx:U11>0.3032</PDBx:U11>
         <PDBx:U12>-0.0992</PDBx:U12>
         <PDBx:U13>-0.0841</PDBx:U13>
         <PDBx:U22>0.8631</PDBx:U22>
         <PDBx:U23>-0.0054</PDBx:U23>
         <PDBx:U33>0.4711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2143">
         <PDBx:U11>0.2720</PDBx:U11>
         <PDBx:U12>-0.0923</PDBx:U12>
         <PDBx:U13>-0.0822</PDBx:U13>
         <PDBx:U22>0.7809</PDBx:U22>
         <PDBx:U23>0.0059</PDBx:U23>
         <PDBx:U33>0.4107</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2144">
         <PDBx:U11>0.3040</PDBx:U11>
         <PDBx:U12>-0.1093</PDBx:U12>
         <PDBx:U13>-0.0671</PDBx:U13>
         <PDBx:U22>0.7763</PDBx:U22>
         <PDBx:U23>-0.0069</PDBx:U23>
         <PDBx:U33>0.4152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>344</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>44</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2145">
         <PDBx:U11>0.2829</PDBx:U11>
         <PDBx:U12>-0.0666</PDBx:U12>
         <PDBx:U13>-0.0960</PDBx:U13>
         <PDBx:U22>0.7885</PDBx:U22>
         <PDBx:U23>0.0296</PDBx:U23>
         <PDBx:U33>0.4283</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2146">
         <PDBx:U11>0.2991</PDBx:U11>
         <PDBx:U12>-0.0592</PDBx:U12>
         <PDBx:U13>-0.0942</PDBx:U13>
         <PDBx:U22>0.7588</PDBx:U22>
         <PDBx:U23>0.0410</PDBx:U23>
         <PDBx:U33>0.4192</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2147">
         <PDBx:U11>0.2655</PDBx:U11>
         <PDBx:U12>-0.0590</PDBx:U12>
         <PDBx:U13>-0.0761</PDBx:U13>
         <PDBx:U22>0.6770</PDBx:U22>
         <PDBx:U23>0.0304</PDBx:U23>
         <PDBx:U33>0.3853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2148">
         <PDBx:U11>0.2568</PDBx:U11>
         <PDBx:U12>-0.0717</PDBx:U12>
         <PDBx:U13>-0.0667</PDBx:U13>
         <PDBx:U22>0.6341</PDBx:U22>
         <PDBx:U23>0.0228</PDBx:U23>
         <PDBx:U33>0.3502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2149">
         <PDBx:U11>0.3757</PDBx:U11>
         <PDBx:U12>-0.0291</PDBx:U12>
         <PDBx:U13>-0.1087</PDBx:U13>
         <PDBx:U22>0.8369</PDBx:U22>
         <PDBx:U23>0.0684</PDBx:U23>
         <PDBx:U33>0.5041</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2150">
         <PDBx:U11>0.4078</PDBx:U11>
         <PDBx:U12>-0.0235</PDBx:U12>
         <PDBx:U13>-0.1292</PDBx:U13>
         <PDBx:U22>0.9089</PDBx:U22>
         <PDBx:U23>0.0854</PDBx:U23>
         <PDBx:U33>0.5304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2151">
         <PDBx:U11>0.4118</PDBx:U11>
         <PDBx:U12>0.0103</PDBx:U12>
         <PDBx:U13>-0.1383</PDBx:U13>
         <PDBx:U22>0.8984</PDBx:U22>
         <PDBx:U23>0.1135</PDBx:U23>
         <PDBx:U33>0.5399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2152">
         <PDBx:U11>0.4582</PDBx:U11>
         <PDBx:U12>-0.0485</PDBx:U12>
         <PDBx:U13>-0.1310</PDBx:U13>
         <PDBx:U22>0.9566</PDBx:U22>
         <PDBx:U23>0.0812</PDBx:U23>
         <PDBx:U33>0.5401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>345</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>45</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2153">
         <PDBx:U11>0.2127</PDBx:U11>
         <PDBx:U12>-0.0444</PDBx:U12>
         <PDBx:U13>-0.0708</PDBx:U13>
         <PDBx:U22>0.6224</PDBx:U22>
         <PDBx:U23>0.0299</PDBx:U23>
         <PDBx:U33>0.3631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2154">
         <PDBx:U11>0.2385</PDBx:U11>
         <PDBx:U12>-0.0429</PDBx:U12>
         <PDBx:U13>-0.0545</PDBx:U13>
         <PDBx:U22>0.6059</PDBx:U22>
         <PDBx:U23>0.0217</PDBx:U23>
         <PDBx:U33>0.3896</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2155">
         <PDBx:U11>0.2485</PDBx:U11>
         <PDBx:U12>-0.0674</PDBx:U12>
         <PDBx:U13>-0.0391</PDBx:U13>
         <PDBx:U22>0.5975</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.3827</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2156">
         <PDBx:U11>0.1418</PDBx:U11>
         <PDBx:U12>-0.0709</PDBx:U12>
         <PDBx:U13>-0.0288</PDBx:U13>
         <PDBx:U22>0.4505</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.2584</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2157">
         <PDBx:U11>0.1797</PDBx:U11>
         <PDBx:U12>-0.0256</PDBx:U12>
         <PDBx:U13>-0.0488</PDBx:U13>
         <PDBx:U22>0.5521</PDBx:U22>
         <PDBx:U23>0.0237</PDBx:U23>
         <PDBx:U33>0.3672</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2158">
         <PDBx:U11>0.1824</PDBx:U11>
         <PDBx:U12>0.0031</PDBx:U12>
         <PDBx:U13>-0.0582</PDBx:U13>
         <PDBx:U22>0.5621</PDBx:U22>
         <PDBx:U23>0.0453</PDBx:U23>
         <PDBx:U33>0.3878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2159">
         <PDBx:U11>0.2022</PDBx:U11>
         <PDBx:U12>0.0176</PDBx:U12>
         <PDBx:U13>-0.0462</PDBx:U13>
         <PDBx:U22>0.5801</PDBx:U22>
         <PDBx:U23>0.0426</PDBx:U23>
         <PDBx:U33>0.4431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2160">
         <PDBx:U11>0.2235</PDBx:U11>
         <PDBx:U12>0.0128</PDBx:U12>
         <PDBx:U13>-0.0591</PDBx:U13>
         <PDBx:U22>0.5665</PDBx:U22>
         <PDBx:U23>0.0594</PDBx:U23>
         <PDBx:U33>0.4028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>346</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>46</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2161">
         <PDBx:U11>0.1672</PDBx:U11>
         <PDBx:U12>-0.0831</PDBx:U12>
         <PDBx:U13>-0.0367</PDBx:U13>
         <PDBx:U22>0.5453</PDBx:U22>
         <PDBx:U23>-0.0133</PDBx:U23>
         <PDBx:U33>0.3067</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2162">
         <PDBx:U11>0.1844</PDBx:U11>
         <PDBx:U12>-0.1057</PDBx:U12>
         <PDBx:U13>-0.0191</PDBx:U13>
         <PDBx:U22>0.5425</PDBx:U22>
         <PDBx:U23>-0.0345</PDBx:U23>
         <PDBx:U33>0.3046</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2163">
         <PDBx:U11>0.2072</PDBx:U11>
         <PDBx:U12>-0.1185</PDBx:U12>
         <PDBx:U13>-0.0169</PDBx:U13>
         <PDBx:U22>0.5448</PDBx:U22>
         <PDBx:U23>-0.0379</PDBx:U23>
         <PDBx:U33>0.2920</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2164">
         <PDBx:U11>0.2458</PDBx:U11>
         <PDBx:U12>-0.1246</PDBx:U12>
         <PDBx:U13>-0.0019</PDBx:U13>
         <PDBx:U22>0.5415</PDBx:U22>
         <PDBx:U23>-0.0478</PDBx:U23>
         <PDBx:U33>0.3125</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2165">
         <PDBx:U11>0.2909</PDBx:U11>
         <PDBx:U12>-0.1220</PDBx:U12>
         <PDBx:U13>-0.0161</PDBx:U13>
         <PDBx:U22>0.6893</PDBx:U22>
         <PDBx:U23>-0.0491</PDBx:U23>
         <PDBx:U33>0.4219</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2166">
         <PDBx:U11>0.2755</PDBx:U11>
         <PDBx:U12>-0.1104</PDBx:U12>
         <PDBx:U13>-0.0163</PDBx:U13>
         <PDBx:U22>0.6940</PDBx:U22>
         <PDBx:U23>-0.0470</PDBx:U23>
         <PDBx:U33>0.4433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2167">
         <PDBx:U11>0.3119</PDBx:U11>
         <PDBx:U12>-0.1443</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>0.6822</PDBx:U22>
         <PDBx:U23>-0.0721</PDBx:U23>
         <PDBx:U33>0.4189</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>347</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>47</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2168">
         <PDBx:U11>0.2109</PDBx:U11>
         <PDBx:U12>-0.1218</PDBx:U12>
         <PDBx:U13>-0.0309</PDBx:U13>
         <PDBx:U22>0.5782</PDBx:U22>
         <PDBx:U23>-0.0291</PDBx:U23>
         <PDBx:U33>0.2868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2169">
         <PDBx:U11>0.2661</PDBx:U11>
         <PDBx:U12>-0.1356</PDBx:U12>
         <PDBx:U13>-0.0273</PDBx:U13>
         <PDBx:U22>0.6173</PDBx:U22>
         <PDBx:U23>-0.0318</PDBx:U23>
         <PDBx:U33>0.3096</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2170">
         <PDBx:U11>0.2472</PDBx:U11>
         <PDBx:U12>-0.1249</PDBx:U12>
         <PDBx:U13>-0.0236</PDBx:U13>
         <PDBx:U22>0.5515</PDBx:U22>
         <PDBx:U23>-0.0257</PDBx:U23>
         <PDBx:U33>0.2801</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2171">
         <PDBx:U11>0.2741</PDBx:U11>
         <PDBx:U12>-0.1348</PDBx:U12>
         <PDBx:U13>-0.0101</PDBx:U13>
         <PDBx:U22>0.5461</PDBx:U22>
         <PDBx:U23>-0.0366</PDBx:U23>
         <PDBx:U33>0.2862</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2172">
         <PDBx:U11>0.2534</PDBx:U11>
         <PDBx:U12>-0.1390</PDBx:U12>
         <PDBx:U13>-0.0447</PDBx:U13>
         <PDBx:U22>0.6456</PDBx:U22>
         <PDBx:U23>-0.0189</PDBx:U23>
         <PDBx:U33>0.2904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2173">
         <PDBx:U11>0.4132</PDBx:U11>
         <PDBx:U12>-0.1569</PDBx:U12>
         <PDBx:U13>-0.0385</PDBx:U13>
         <PDBx:U22>0.7904</PDBx:U22>
         <PDBx:U23>-0.0225</PDBx:U23>
         <PDBx:U33>0.4168</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2174">
         <PDBx:U11>0.3972</PDBx:U11>
         <PDBx:U12>-0.1499</PDBx:U12>
         <PDBx:U13>-0.0404</PDBx:U13>
         <PDBx:U22>0.7464</PDBx:U22>
         <PDBx:U23>-0.0128</PDBx:U23>
         <PDBx:U33>0.3894</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2175">
         <PDBx:U11>0.4646</PDBx:U11>
         <PDBx:U12>-0.1817</PDBx:U12>
         <PDBx:U13>-0.0289</PDBx:U13>
         <PDBx:U22>0.8609</PDBx:U22>
         <PDBx:U23>-0.0379</PDBx:U23>
         <PDBx:U33>0.4525</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>348</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>48</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2176">
         <PDBx:U11>0.2221</PDBx:U11>
         <PDBx:U12>-0.1038</PDBx:U12>
         <PDBx:U13>-0.0345</PDBx:U13>
         <PDBx:U22>0.5243</PDBx:U22>
         <PDBx:U23>-0.0091</PDBx:U23>
         <PDBx:U33>0.2708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2177">
         <PDBx:U11>0.1771</PDBx:U11>
         <PDBx:U12>-0.0940</PDBx:U12>
         <PDBx:U13>-0.0320</PDBx:U13>
         <PDBx:U22>0.4414</PDBx:U22>
         <PDBx:U23>-0.0037</PDBx:U23>
         <PDBx:U33>0.2182</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2178">
         <PDBx:U11>0.2082</PDBx:U11>
         <PDBx:U12>-0.0937</PDBx:U12>
         <PDBx:U13>-0.0160</PDBx:U13>
         <PDBx:U22>0.4358</PDBx:U22>
         <PDBx:U23>-0.0167</PDBx:U23>
         <PDBx:U33>0.2511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2179">
         <PDBx:U11>0.2371</PDBx:U11>
         <PDBx:U12>-0.0975</PDBx:U12>
         <PDBx:U13>-0.0074</PDBx:U13>
         <PDBx:U22>0.4329</PDBx:U22>
         <PDBx:U23>-0.0233</PDBx:U23>
         <PDBx:U33>0.2643</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2180">
         <PDBx:U11>0.1594</PDBx:U11>
         <PDBx:U12>-0.0713</PDBx:U12>
         <PDBx:U13>-0.0446</PDBx:U13>
         <PDBx:U22>0.4314</PDBx:U22>
         <PDBx:U23>0.0162</PDBx:U23>
         <PDBx:U33>0.2169</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2181">
         <PDBx:U11>0.2120</PDBx:U11>
         <PDBx:U12>-0.0615</PDBx:U12>
         <PDBx:U13>-0.0421</PDBx:U13>
         <PDBx:U22>0.4504</PDBx:U22>
         <PDBx:U23>0.0216</PDBx:U23>
         <PDBx:U33>0.2640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2182">
         <PDBx:U11>0.2179</PDBx:U11>
         <PDBx:U12>-0.0745</PDBx:U12>
         <PDBx:U13>-0.0413</PDBx:U13>
         <PDBx:U22>0.4391</PDBx:U22>
         <PDBx:U23>0.0191</PDBx:U23>
         <PDBx:U33>0.2419</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2183">
         <PDBx:U11>0.2711</PDBx:U11>
         <PDBx:U12>-0.0376</PDBx:U12>
         <PDBx:U13>-0.0511</PDBx:U13>
         <PDBx:U22>0.5167</PDBx:U22>
         <PDBx:U23>0.0424</PDBx:U23>
         <PDBx:U33>0.3385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>349</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>49</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2184">
         <PDBx:U11>0.1884</PDBx:U11>
         <PDBx:U12>-0.0884</PDBx:U12>
         <PDBx:U13>-0.0115</PDBx:U13>
         <PDBx:U22>0.4209</PDBx:U22>
         <PDBx:U23>-0.0197</PDBx:U23>
         <PDBx:U33>0.2514</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2185">
         <PDBx:U11>0.2022</PDBx:U11>
         <PDBx:U12>-0.0876</PDBx:U12>
         <PDBx:U13>0.0039</PDBx:U13>
         <PDBx:U22>0.4010</PDBx:U22>
         <PDBx:U23>-0.0288</PDBx:U23>
         <PDBx:U33>0.2657</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2186">
         <PDBx:U11>0.2480</PDBx:U11>
         <PDBx:U12>-0.1024</PDBx:U12>
         <PDBx:U13>0.0181</PDBx:U13>
         <PDBx:U22>0.4227</PDBx:U22>
         <PDBx:U23>-0.0443</PDBx:U23>
         <PDBx:U33>0.2905</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2187">
         <PDBx:U11>0.2685</PDBx:U11>
         <PDBx:U12>-0.0992</PDBx:U12>
         <PDBx:U13>0.0280</PDBx:U13>
         <PDBx:U22>0.4084</PDBx:U22>
         <PDBx:U23>-0.0479</PDBx:U23>
         <PDBx:U33>0.3032</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2188">
         <PDBx:U11>0.2061</PDBx:U11>
         <PDBx:U12>-0.0841</PDBx:U12>
         <PDBx:U13>0.0095</PDBx:U13>
         <PDBx:U22>0.4165</PDBx:U22>
         <PDBx:U23>-0.0306</PDBx:U23>
         <PDBx:U33>0.2912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>350</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>50</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2189">
         <PDBx:U11>0.2562</PDBx:U11>
         <PDBx:U12>-0.1181</PDBx:U12>
         <PDBx:U13>0.0201</PDBx:U13>
         <PDBx:U22>0.4516</PDBx:U22>
         <PDBx:U23>-0.0537</PDBx:U23>
         <PDBx:U33>0.2902</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2190">
         <PDBx:U11>0.3349</PDBx:U11>
         <PDBx:U12>-0.1330</PDBx:U12>
         <PDBx:U13>0.0367</PDBx:U13>
         <PDBx:U22>0.5086</PDBx:U22>
         <PDBx:U23>-0.0707</PDBx:U23>
         <PDBx:U33>0.3482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2191">
         <PDBx:U11>0.3243</PDBx:U11>
         <PDBx:U12>-0.1313</PDBx:U12>
         <PDBx:U13>0.0393</PDBx:U13>
         <PDBx:U22>0.4724</PDBx:U22>
         <PDBx:U23>-0.0705</PDBx:U23>
         <PDBx:U33>0.3217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2192">
         <PDBx:U11>0.3611</PDBx:U11>
         <PDBx:U12>-0.1305</PDBx:U12>
         <PDBx:U13>0.0538</PDBx:U13>
         <PDBx:U22>0.4743</PDBx:U22>
         <PDBx:U23>-0.0793</PDBx:U23>
         <PDBx:U33>0.3517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2193">
         <PDBx:U11>0.4248</PDBx:U11>
         <PDBx:U12>-0.1526</PDBx:U12>
         <PDBx:U13>0.0383</PDBx:U13>
         <PDBx:U22>0.6327</PDBx:U22>
         <PDBx:U23>-0.0817</PDBx:U23>
         <PDBx:U33>0.4298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2194">
         <PDBx:U11>0.4899</PDBx:U11>
         <PDBx:U12>-0.1694</PDBx:U12>
         <PDBx:U13>0.0584</PDBx:U13>
         <PDBx:U22>0.6749</PDBx:U22>
         <PDBx:U23>-0.1016</PDBx:U23>
         <PDBx:U33>0.4708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2195">
         <PDBx:U11>0.4454</PDBx:U11>
         <PDBx:U12>-0.1729</PDBx:U12>
         <PDBx:U13>0.0756</PDBx:U13>
         <PDBx:U22>0.6036</PDBx:U22>
         <PDBx:U23>-0.1150</PDBx:U23>
         <PDBx:U33>0.4244</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2196">
         <PDBx:U11>0.4975</PDBx:U11>
         <PDBx:U12>-0.1795</PDBx:U12>
         <PDBx:U13>0.0591</PDBx:U13>
         <PDBx:U22>0.6891</PDBx:U22>
         <PDBx:U23>-0.1043</PDBx:U23>
         <PDBx:U33>0.4603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>351</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>51</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2197">
         <PDBx:U11>0.2764</PDBx:U11>
         <PDBx:U12>-0.1305</PDBx:U12>
         <PDBx:U13>0.0264</PDBx:U13>
         <PDBx:U22>0.4418</PDBx:U22>
         <PDBx:U23>-0.0604</PDBx:U23>
         <PDBx:U33>0.2689</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2198">
         <PDBx:U11>0.2377</PDBx:U11>
         <PDBx:U12>-0.1300</PDBx:U12>
         <PDBx:U13>0.0296</PDBx:U13>
         <PDBx:U22>0.3814</PDBx:U22>
         <PDBx:U23>-0.0609</PDBx:U23>
         <PDBx:U33>0.2163</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2199">
         <PDBx:U11>0.2336</PDBx:U11>
         <PDBx:U12>-0.1128</PDBx:U12>
         <PDBx:U13>0.0295</PDBx:U13>
         <PDBx:U22>0.3490</PDBx:U22>
         <PDBx:U23>-0.0555</PDBx:U23>
         <PDBx:U33>0.2232</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2200">
         <PDBx:U11>0.2602</PDBx:U11>
         <PDBx:U12>-0.1108</PDBx:U12>
         <PDBx:U13>0.0390</PDBx:U13>
         <PDBx:U22>0.3507</PDBx:U22>
         <PDBx:U23>-0.0620</PDBx:U23>
         <PDBx:U33>0.2450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2201">
         <PDBx:U11>0.2214</PDBx:U11>
         <PDBx:U12>-0.1360</PDBx:U12>
         <PDBx:U13>0.0174</PDBx:U13>
         <PDBx:U22>0.3895</PDBx:U22>
         <PDBx:U23>-0.0505</PDBx:U23>
         <PDBx:U33>0.1896</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2202">
         <PDBx:U11>0.3135</PDBx:U11>
         <PDBx:U12>-0.1578</PDBx:U12>
         <PDBx:U13>0.0217</PDBx:U13>
         <PDBx:U22>0.5074</PDBx:U22>
         <PDBx:U23>-0.0580</PDBx:U23>
         <PDBx:U33>0.2641</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2203">
         <PDBx:U11>0.3673</PDBx:U11>
         <PDBx:U12>-0.1654</PDBx:U12>
         <PDBx:U13>0.0091</PDBx:U13>
         <PDBx:U22>0.5864</PDBx:U22>
         <PDBx:U23>-0.0444</PDBx:U23>
         <PDBx:U33>0.3073</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2204">
         <PDBx:U11>0.3589</PDBx:U11>
         <PDBx:U12>-0.1563</PDBx:U12>
         <PDBx:U13>-0.0114</PDBx:U13>
         <PDBx:U22>0.6136</PDBx:U22>
         <PDBx:U23>-0.0275</PDBx:U23>
         <PDBx:U33>0.3159</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2205">
         <PDBx:U11>0.3782</PDBx:U11>
         <PDBx:U12>-0.1412</PDBx:U12>
         <PDBx:U13>-0.0260</PDBx:U13>
         <PDBx:U22>0.6328</PDBx:U22>
         <PDBx:U23>-0.0098</PDBx:U23>
         <PDBx:U33>0.3422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2206">
         <PDBx:U11>0.2731</PDBx:U11>
         <PDBx:U12>-0.1378</PDBx:U12>
         <PDBx:U13>-0.0222</PDBx:U13>
         <PDBx:U22>0.4955</PDBx:U22>
         <PDBx:U23>-0.0083</PDBx:U23>
         <PDBx:U33>0.2276</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2207">
         <PDBx:U11>0.3502</PDBx:U11>
         <PDBx:U12>-0.1284</PDBx:U12>
         <PDBx:U13>-0.0434</PDBx:U13>
         <PDBx:U22>0.6367</PDBx:U22>
         <PDBx:U23>0.0056</PDBx:U23>
         <PDBx:U33>0.3305</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>352</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>52</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2208">
         <PDBx:U11>0.2253</PDBx:U11>
         <PDBx:U12>-0.1007</PDBx:U12>
         <PDBx:U13>0.0197</PDBx:U13>
         <PDBx:U22>0.3483</PDBx:U22>
         <PDBx:U23>-0.0444</PDBx:U23>
         <PDBx:U33>0.2314</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2209">
         <PDBx:U11>0.2149</PDBx:U11>
         <PDBx:U12>-0.0870</PDBx:U12>
         <PDBx:U13>0.0201</PDBx:U13>
         <PDBx:U22>0.3173</PDBx:U22>
         <PDBx:U23>-0.0402</PDBx:U23>
         <PDBx:U33>0.2305</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2210">
         <PDBx:U11>0.2796</PDBx:U11>
         <PDBx:U12>-0.0859</PDBx:U12>
         <PDBx:U13>0.0356</PDBx:U13>
         <PDBx:U22>0.3561</PDBx:U22>
         <PDBx:U23>-0.0488</PDBx:U23>
         <PDBx:U33>0.2973</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2211">
         <PDBx:U11>0.2493</PDBx:U11>
         <PDBx:U12>-0.0793</PDBx:U12>
         <PDBx:U13>0.0408</PDBx:U13>
         <PDBx:U22>0.3062</PDBx:U22>
         <PDBx:U23>-0.0502</PDBx:U23>
         <PDBx:U33>0.2695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2212">
         <PDBx:U11>0.2280</PDBx:U11>
         <PDBx:U12>-0.0762</PDBx:U12>
         <PDBx:U13>0.0100</PDBx:U13>
         <PDBx:U22>0.3463</PDBx:U22>
         <PDBx:U23>-0.0283</PDBx:U23>
         <PDBx:U33>0.2595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2213">
         <PDBx:U11>0.2126</PDBx:U11>
         <PDBx:U12>-0.0727</PDBx:U12>
         <PDBx:U13>-0.0041</PDBx:U13>
         <PDBx:U22>0.3493</PDBx:U22>
         <PDBx:U23>-0.0166</PDBx:U23>
         <PDBx:U33>0.2435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2214">
         <PDBx:U11>0.2538</PDBx:U11>
         <PDBx:U12>-0.0586</PDBx:U12>
         <PDBx:U13>-0.0108</PDBx:U13>
         <PDBx:U22>0.4041</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.3030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2215">
         <PDBx:U11>0.2451</PDBx:U11>
         <PDBx:U12>-0.0551</PDBx:U12>
         <PDBx:U13>-0.0138</PDBx:U13>
         <PDBx:U22>0.4184</PDBx:U22>
         <PDBx:U23>0.0001</PDBx:U23>
         <PDBx:U33>0.3085</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2216">
         <PDBx:U11>0.2922</PDBx:U11>
         <PDBx:U12>-0.0474</PDBx:U12>
         <PDBx:U13>-0.0105</PDBx:U13>
         <PDBx:U22>0.4225</PDBx:U22>
         <PDBx:U23>-0.0007</PDBx:U23>
         <PDBx:U33>0.3389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>353</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>53</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2217">
         <PDBx:U11>0.2450</PDBx:U11>
         <PDBx:U12>-0.0929</PDBx:U12>
         <PDBx:U13>0.0444</PDBx:U13>
         <PDBx:U22>0.3217</PDBx:U22>
         <PDBx:U23>-0.0549</PDBx:U23>
         <PDBx:U33>0.2623</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2218">
         <PDBx:U11>0.2724</PDBx:U11>
         <PDBx:U12>-0.0926</PDBx:U12>
         <PDBx:U13>0.0628</PDBx:U13>
         <PDBx:U22>0.3180</PDBx:U22>
         <PDBx:U23>-0.0619</PDBx:U23>
         <PDBx:U33>0.2876</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2219">
         <PDBx:U11>0.2767</PDBx:U11>
         <PDBx:U12>-0.0947</PDBx:U12>
         <PDBx:U13>0.0754</PDBx:U13>
         <PDBx:U22>0.2974</PDBx:U22>
         <PDBx:U23>-0.0710</PDBx:U23>
         <PDBx:U33>0.2841</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2220">
         <PDBx:U11>0.3333</PDBx:U11>
         <PDBx:U12>-0.0866</PDBx:U12>
         <PDBx:U13>0.0884</PDBx:U13>
         <PDBx:U22>0.3250</PDBx:U22>
         <PDBx:U23>-0.0701</PDBx:U23>
         <PDBx:U33>0.3447</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2221">
         <PDBx:U11>0.3318</PDBx:U11>
         <PDBx:U12>-0.1034</PDBx:U12>
         <PDBx:U13>0.0723</PDBx:U13>
         <PDBx:U22>0.3797</PDBx:U22>
         <PDBx:U23>-0.0707</PDBx:U23>
         <PDBx:U33>0.3435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2222">
         <PDBx:U11>0.3476</PDBx:U11>
         <PDBx:U12>-0.0992</PDBx:U12>
         <PDBx:U13>0.0694</PDBx:U13>
         <PDBx:U22>0.4082</PDBx:U22>
         <PDBx:U23>-0.0641</PDBx:U23>
         <PDBx:U33>0.3711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2223">
         <PDBx:U11>0.3344</PDBx:U11>
         <PDBx:U12>-0.1128</PDBx:U12>
         <PDBx:U13>0.0803</PDBx:U13>
         <PDBx:U22>0.3992</PDBx:U22>
         <PDBx:U23>-0.0769</PDBx:U23>
         <PDBx:U33>0.3548</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2224">
         <PDBx:U11>0.3667</PDBx:U11>
         <PDBx:U12>-0.0860</PDBx:U12>
         <PDBx:U13>0.0780</PDBx:U13>
         <PDBx:U22>0.3977</PDBx:U22>
         <PDBx:U23>-0.0559</PDBx:U23>
         <PDBx:U33>0.3905</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>354</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>54</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2225">
         <PDBx:U11>0.2737</PDBx:U11>
         <PDBx:U12>-0.1049</PDBx:U12>
         <PDBx:U13>0.0742</PDBx:U13>
         <PDBx:U22>0.3058</PDBx:U22>
         <PDBx:U23>-0.0788</PDBx:U23>
         <PDBx:U33>0.2705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2226">
         <PDBx:U11>0.3295</PDBx:U11>
         <PDBx:U12>-0.1075</PDBx:U12>
         <PDBx:U13>0.0888</PDBx:U13>
         <PDBx:U22>0.3410</PDBx:U22>
         <PDBx:U23>-0.0895</PDBx:U23>
         <PDBx:U33>0.3204</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2227">
         <PDBx:U11>0.3079</PDBx:U11>
         <PDBx:U12>-0.0946</PDBx:U12>
         <PDBx:U13>0.0854</PDBx:U13>
         <PDBx:U22>0.3119</PDBx:U22>
         <PDBx:U23>-0.0833</PDBx:U23>
         <PDBx:U33>0.3115</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2228">
         <PDBx:U11>0.3381</PDBx:U11>
         <PDBx:U12>-0.0892</PDBx:U12>
         <PDBx:U13>0.1017</PDBx:U13>
         <PDBx:U22>0.3177</PDBx:U22>
         <PDBx:U23>-0.0883</PDBx:U23>
         <PDBx:U33>0.3507</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2229">
         <PDBx:U11>0.3651</PDBx:U11>
         <PDBx:U12>-0.1226</PDBx:U12>
         <PDBx:U13>0.0890</PDBx:U13>
         <PDBx:U22>0.3938</PDBx:U22>
         <PDBx:U23>-0.0986</PDBx:U23>
         <PDBx:U33>0.3388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2230">
         <PDBx:U11>0.4365</PDBx:U11>
         <PDBx:U12>-0.1246</PDBx:U12>
         <PDBx:U13>0.1061</PDBx:U13>
         <PDBx:U22>0.4440</PDBx:U22>
         <PDBx:U23>-0.1095</PDBx:U23>
         <PDBx:U33>0.4079</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2231">
         <PDBx:U11>0.3950</PDBx:U11>
         <PDBx:U12>-0.1383</PDBx:U12>
         <PDBx:U13>0.0935</PDBx:U13>
         <PDBx:U22>0.4374</PDBx:U22>
         <PDBx:U23>-0.1077</PDBx:U23>
         <PDBx:U33>0.3574</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>355</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>55</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2232">
         <PDBx:U11>0.2926</PDBx:U11>
         <PDBx:U12>-0.0897</PDBx:U12>
         <PDBx:U13>0.0665</PDBx:U13>
         <PDBx:U22>0.3172</PDBx:U22>
         <PDBx:U23>-0.0730</PDBx:U23>
         <PDBx:U33>0.2990</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2233">
         <PDBx:U11>0.2629</PDBx:U11>
         <PDBx:U12>-0.0795</PDBx:U12>
         <PDBx:U13>0.0621</PDBx:U13>
         <PDBx:U22>0.2851</PDBx:U22>
         <PDBx:U23>-0.0699</PDBx:U23>
         <PDBx:U33>0.2815</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2234">
         <PDBx:U11>0.2506</PDBx:U11>
         <PDBx:U12>-0.0687</PDBx:U12>
         <PDBx:U13>0.0653</PDBx:U13>
         <PDBx:U22>0.2620</PDBx:U22>
         <PDBx:U23>-0.0653</PDBx:U23>
         <PDBx:U33>0.2873</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2235">
         <PDBx:U11>0.2594</PDBx:U11>
         <PDBx:U12>-0.0556</PDBx:U12>
         <PDBx:U13>0.0671</PDBx:U13>
         <PDBx:U22>0.2626</PDBx:U22>
         <PDBx:U23>-0.0659</PDBx:U23>
         <PDBx:U33>0.3087</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2236">
         <PDBx:U11>0.2482</PDBx:U11>
         <PDBx:U12>-0.0781</PDBx:U12>
         <PDBx:U13>0.0444</PDBx:U13>
         <PDBx:U22>0.2895</PDBx:U22>
         <PDBx:U23>-0.0611</PDBx:U23>
         <PDBx:U33>0.2611</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2237">
         <PDBx:U11>0.2539</PDBx:U11>
         <PDBx:U12>-0.0887</PDBx:U12>
         <PDBx:U13>0.0449</PDBx:U13>
         <PDBx:U22>0.3020</PDBx:U22>
         <PDBx:U23>-0.0640</PDBx:U23>
         <PDBx:U33>0.2497</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2238">
         <PDBx:U11>0.2896</PDBx:U11>
         <PDBx:U12>-0.0901</PDBx:U12>
         <PDBx:U13>0.0513</PDBx:U13>
         <PDBx:U22>0.3321</PDBx:U22>
         <PDBx:U23>-0.0702</PDBx:U23>
         <PDBx:U33>0.2830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2239">
         <PDBx:U11>0.3086</PDBx:U11>
         <PDBx:U12>-0.1004</PDBx:U12>
         <PDBx:U13>0.0411</PDBx:U13>
         <PDBx:U22>0.3717</PDBx:U22>
         <PDBx:U23>-0.0621</PDBx:U23>
         <PDBx:U33>0.2891</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2240">
         <PDBx:U11>0.3231</PDBx:U11>
         <PDBx:U12>-0.1028</PDBx:U12>
         <PDBx:U13>0.0525</PDBx:U13>
         <PDBx:U22>0.3730</PDBx:U22>
         <PDBx:U23>-0.0716</PDBx:U23>
         <PDBx:U33>0.2970</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2241">
         <PDBx:U11>0.3602</PDBx:U11>
         <PDBx:U12>-0.1098</PDBx:U12>
         <PDBx:U13>0.0457</PDBx:U13>
         <PDBx:U22>0.4241</PDBx:U22>
         <PDBx:U23>-0.0664</PDBx:U23>
         <PDBx:U33>0.3258</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>356</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>56</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2242">
         <PDBx:U11>0.2538</PDBx:U11>
         <PDBx:U12>-0.0680</PDBx:U12>
         <PDBx:U13>0.0644</PDBx:U13>
         <PDBx:U22>0.2663</PDBx:U22>
         <PDBx:U23>-0.0583</PDBx:U23>
         <PDBx:U33>0.2884</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2243">
         <PDBx:U11>0.2840</PDBx:U11>
         <PDBx:U12>-0.0446</PDBx:U12>
         <PDBx:U13>0.0618</PDBx:U13>
         <PDBx:U22>0.2799</PDBx:U22>
         <PDBx:U23>-0.0468</PDBx:U23>
         <PDBx:U33>0.3164</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2244">
         <PDBx:U11>0.3329</PDBx:U11>
         <PDBx:U12>-0.0340</PDBx:U12>
         <PDBx:U13>0.0797</PDBx:U13>
         <PDBx:U22>0.2952</PDBx:U22>
         <PDBx:U23>-0.0466</PDBx:U23>
         <PDBx:U33>0.3638</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2245">
         <PDBx:U11>0.3279</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>0.0744</PDBx:U13>
         <PDBx:U22>0.2800</PDBx:U22>
         <PDBx:U23>-0.0375</PDBx:U23>
         <PDBx:U33>0.3595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2246">
         <PDBx:U11>0.2717</PDBx:U11>
         <PDBx:U12>-0.0463</PDBx:U12>
         <PDBx:U13>0.0599</PDBx:U13>
         <PDBx:U22>0.2723</PDBx:U22>
         <PDBx:U23>-0.0406</PDBx:U23>
         <PDBx:U33>0.2979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2247">
         <PDBx:U11>0.2863</PDBx:U11>
         <PDBx:U12>-0.0255</PDBx:U12>
         <PDBx:U13>0.0580</PDBx:U13>
         <PDBx:U22>0.2681</PDBx:U22>
         <PDBx:U23>-0.0292</PDBx:U23>
         <PDBx:U33>0.3032</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2248">
         <PDBx:U11>0.2906</PDBx:U11>
         <PDBx:U12>-0.0315</PDBx:U12>
         <PDBx:U13>0.0666</PDBx:U13>
         <PDBx:U22>0.2682</PDBx:U22>
         <PDBx:U23>-0.0264</PDBx:U23>
         <PDBx:U33>0.3000</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2249">
         <PDBx:U11>0.1707</PDBx:U11>
         <PDBx:U12>-0.0401</PDBx:U12>
         <PDBx:U13>0.0506</PDBx:U13>
         <PDBx:U22>0.1912</PDBx:U22>
         <PDBx:U23>-0.0271</PDBx:U23>
         <PDBx:U33>0.1964</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>357</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>57</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2250">
         <PDBx:U11>0.3312</PDBx:U11>
         <PDBx:U12>-0.0514</PDBx:U12>
         <PDBx:U13>0.1018</PDBx:U13>
         <PDBx:U22>0.2769</PDBx:U22>
         <PDBx:U23>-0.0565</PDBx:U23>
         <PDBx:U33>0.3590</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2251">
         <PDBx:U11>0.3906</PDBx:U11>
         <PDBx:U12>-0.0418</PDBx:U12>
         <PDBx:U13>0.1253</PDBx:U13>
         <PDBx:U22>0.2953</PDBx:U22>
         <PDBx:U23>-0.0558</PDBx:U23>
         <PDBx:U33>0.4155</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2252">
         <PDBx:U11>0.3856</PDBx:U11>
         <PDBx:U12>-0.0253</PDBx:U12>
         <PDBx:U13>0.1254</PDBx:U13>
         <PDBx:U22>0.2867</PDBx:U22>
         <PDBx:U23>-0.0564</PDBx:U23>
         <PDBx:U33>0.4269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2253">
         <PDBx:U11>0.4552</PDBx:U11>
         <PDBx:U12>0.0009</PDBx:U12>
         <PDBx:U13>0.1294</PDBx:U13>
         <PDBx:U22>0.3336</PDBx:U22>
         <PDBx:U23>-0.0446</PDBx:U23>
         <PDBx:U33>0.4983</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2254">
         <PDBx:U11>0.4739</PDBx:U11>
         <PDBx:U12>-0.0658</PDBx:U12>
         <PDBx:U13>0.1482</PDBx:U13>
         <PDBx:U22>0.3651</PDBx:U22>
         <PDBx:U23>-0.0701</PDBx:U23>
         <PDBx:U33>0.4907</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2255">
         <PDBx:U11>0.4643</PDBx:U11>
         <PDBx:U12>-0.0746</PDBx:U12>
         <PDBx:U13>0.1438</PDBx:U13>
         <PDBx:U22>0.3602</PDBx:U22>
         <PDBx:U23>-0.0729</PDBx:U23>
         <PDBx:U33>0.4660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2256">
         <PDBx:U11>0.5654</PDBx:U11>
         <PDBx:U12>-0.0586</PDBx:U12>
         <PDBx:U13>0.1747</PDBx:U13>
         <PDBx:U22>0.4204</PDBx:U22>
         <PDBx:U23>-0.0617</PDBx:U23>
         <PDBx:U33>0.5837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2257">
         <PDBx:U11>0.5278</PDBx:U11>
         <PDBx:U12>-0.0919</PDBx:U12>
         <PDBx:U13>0.1522</PDBx:U13>
         <PDBx:U22>0.4245</PDBx:U22>
         <PDBx:U23>-0.0896</PDBx:U23>
         <PDBx:U33>0.5180</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>358</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>58</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2258">
         <PDBx:U11>0.3435</PDBx:U11>
         <PDBx:U12>-0.0405</PDBx:U12>
         <PDBx:U13>0.1205</PDBx:U13>
         <PDBx:U22>0.2690</PDBx:U22>
         <PDBx:U23>-0.0692</PDBx:U23>
         <PDBx:U33>0.3967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2259">
         <PDBx:U11>0.3735</PDBx:U11>
         <PDBx:U12>-0.0289</PDBx:U12>
         <PDBx:U13>0.1201</PDBx:U13>
         <PDBx:U22>0.3034</PDBx:U22>
         <PDBx:U23>-0.0721</PDBx:U23>
         <PDBx:U33>0.4470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2260">
         <PDBx:U11>0.3474</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>0.0960</PDBx:U13>
         <PDBx:U22>0.3006</PDBx:U22>
         <PDBx:U23>-0.0637</PDBx:U23>
         <PDBx:U33>0.4312</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2261">
         <PDBx:U11>0.3834</PDBx:U11>
         <PDBx:U12>0.0149</PDBx:U12>
         <PDBx:U13>0.0953</PDBx:U13>
         <PDBx:U22>0.3410</PDBx:U22>
         <PDBx:U23>-0.0634</PDBx:U23>
         <PDBx:U33>0.4878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2262">
         <PDBx:U11>0.4421</PDBx:U11>
         <PDBx:U12>-0.0575</PDBx:U12>
         <PDBx:U13>0.1242</PDBx:U13>
         <PDBx:U22>0.3899</PDBx:U22>
         <PDBx:U23>-0.0870</PDBx:U23>
         <PDBx:U33>0.5207</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2263">
         <PDBx:U11>0.5608</PDBx:U11>
         <PDBx:U12>-0.0739</PDBx:U12>
         <PDBx:U13>0.1435</PDBx:U13>
         <PDBx:U22>0.4962</PDBx:U22>
         <PDBx:U23>-0.0919</PDBx:U23>
         <PDBx:U33>0.6278</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2264">
         <PDBx:U11>0.6315</PDBx:U11>
         <PDBx:U12>-0.0741</PDBx:U12>
         <PDBx:U13>0.1620</PDBx:U13>
         <PDBx:U22>0.5487</PDBx:U22>
         <PDBx:U23>-0.0937</PDBx:U23>
         <PDBx:U33>0.7127</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2265">
         <PDBx:U11>0.5115</PDBx:U11>
         <PDBx:U12>-0.0829</PDBx:U12>
         <PDBx:U13>0.1365</PDBx:U13>
         <PDBx:U22>0.4537</PDBx:U22>
         <PDBx:U23>-0.0973</PDBx:U23>
         <PDBx:U33>0.5491</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>359</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>59</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2266">
         <PDBx:U11>0.3265</PDBx:U11>
         <PDBx:U12>-0.0069</PDBx:U12>
         <PDBx:U13>0.0761</PDBx:U13>
         <PDBx:U22>0.2984</PDBx:U22>
         <PDBx:U23>-0.0569</PDBx:U23>
         <PDBx:U33>0.3977</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.2987</PDBx:U11>
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         <PDBx:U13>0.0544</PDBx:U13>
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         <PDBx:U23>-0.0494</PDBx:U23>
         <PDBx:U33>0.3742</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2268">
         <PDBx:U11>0.3204</PDBx:U11>
         <PDBx:U12>0.0388</PDBx:U12>
         <PDBx:U13>0.0515</PDBx:U13>
         <PDBx:U22>0.2995</PDBx:U22>
         <PDBx:U23>-0.0338</PDBx:U23>
         <PDBx:U33>0.3908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.3075</PDBx:U11>
         <PDBx:U12>0.0588</PDBx:U12>
         <PDBx:U13>0.0394</PDBx:U13>
         <PDBx:U22>0.3037</PDBx:U22>
         <PDBx:U23>-0.0300</PDBx:U23>
         <PDBx:U33>0.3901</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2270">
         <PDBx:U11>0.2454</PDBx:U11>
         <PDBx:U12>0.0006</PDBx:U12>
         <PDBx:U13>0.0397</PDBx:U13>
         <PDBx:U22>0.2547</PDBx:U22>
         <PDBx:U23>-0.0467</PDBx:U23>
         <PDBx:U33>0.3073</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2271">
         <PDBx:U11>0.2878</PDBx:U11>
         <PDBx:U12>0.0173</PDBx:U12>
         <PDBx:U13>0.0232</PDBx:U13>
         <PDBx:U22>0.3081</PDBx:U22>
         <PDBx:U23>-0.0380</PDBx:U23>
         <PDBx:U33>0.3449</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2272">
         <PDBx:U11>0.2463</PDBx:U11>
         <PDBx:U12>0.0222</PDBx:U12>
         <PDBx:U13>0.0110</PDBx:U13>
         <PDBx:U22>0.2902</PDBx:U22>
         <PDBx:U23>-0.0432</PDBx:U23>
         <PDBx:U33>0.3132</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2273">
         <PDBx:U11>0.3006</PDBx:U11>
         <PDBx:U12>0.0270</PDBx:U12>
         <PDBx:U13>0.0198</PDBx:U13>
         <PDBx:U22>0.3091</PDBx:U22>
         <PDBx:U23>-0.0256</PDBx:U23>
         <PDBx:U33>0.3395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2274">
         <PDBx:U11>0.2237</PDBx:U11>
         <PDBx:U12>0.0335</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.2730</PDBx:U22>
         <PDBx:U23>-0.0353</PDBx:U23>
         <PDBx:U33>0.2788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2275">
         <PDBx:U11>0.2850</PDBx:U11>
         <PDBx:U12>0.0371</PDBx:U12>
         <PDBx:U13>0.0045</PDBx:U13>
         <PDBx:U22>0.3114</PDBx:U22>
         <PDBx:U23>-0.0237</PDBx:U23>
         <PDBx:U33>0.3216</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2276">
         <PDBx:U11>0.2812</PDBx:U11>
         <PDBx:U12>0.0253</PDBx:U12>
         <PDBx:U13>0.0304</PDBx:U13>
         <PDBx:U22>0.2660</PDBx:U22>
         <PDBx:U23>-0.0182</PDBx:U23>
         <PDBx:U33>0.3046</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2277">
         <PDBx:U11>0.2973</PDBx:U11>
         <PDBx:U12>0.0453</PDBx:U12>
         <PDBx:U13>-0.0008</PDBx:U13>
         <PDBx:U22>0.3169</PDBx:U22>
         <PDBx:U23>-0.0139</PDBx:U23>
         <PDBx:U33>0.3137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2278">
         <PDBx:U11>0.2793</PDBx:U11>
         <PDBx:U12>0.0346</PDBx:U12>
         <PDBx:U13>0.0259</PDBx:U13>
         <PDBx:U22>0.2557</PDBx:U22>
         <PDBx:U23>-0.0081</PDBx:U23>
         <PDBx:U33>0.2842</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2279">
         <PDBx:U11>0.2735</PDBx:U11>
         <PDBx:U12>0.0445</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.2665</PDBx:U22>
         <PDBx:U23>-0.0055</PDBx:U23>
         <PDBx:U33>0.2737</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>360</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>60</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2280">
         <PDBx:U11>0.2895</PDBx:U11>
         <PDBx:U12>0.0388</PDBx:U12>
         <PDBx:U13>0.0627</PDBx:U13>
         <PDBx:U22>0.2391</PDBx:U22>
         <PDBx:U23>-0.0250</PDBx:U23>
         <PDBx:U33>0.3401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2281">
         <PDBx:U11>0.2709</PDBx:U11>
         <PDBx:U12>0.0635</PDBx:U12>
         <PDBx:U13>0.0627</PDBx:U13>
         <PDBx:U22>0.1982</PDBx:U22>
         <PDBx:U23>-0.0075</PDBx:U23>
         <PDBx:U33>0.3065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2282">
         <PDBx:U11>0.3493</PDBx:U11>
         <PDBx:U12>0.0880</PDBx:U12>
         <PDBx:U13>0.0700</PDBx:U13>
         <PDBx:U22>0.2652</PDBx:U22>
         <PDBx:U23>-0.0017</PDBx:U23>
         <PDBx:U33>0.4010</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2283">
         <PDBx:U11>0.3594</PDBx:U11>
         <PDBx:U12>0.1154</PDBx:U12>
         <PDBx:U13>0.0575</PDBx:U13>
         <PDBx:U22>0.2789</PDBx:U22>
         <PDBx:U23>0.0139</PDBx:U23>
         <PDBx:U33>0.4074</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2284">
         <PDBx:U11>0.3365</PDBx:U11>
         <PDBx:U12>0.0539</PDBx:U12>
         <PDBx:U13>0.0810</PDBx:U13>
         <PDBx:U22>0.2276</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.3475</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>361</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>61</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2285">
         <PDBx:U11>0.3729</PDBx:U11>
         <PDBx:U12>0.0783</PDBx:U12>
         <PDBx:U13>0.0906</PDBx:U13>
         <PDBx:U22>0.2768</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.4427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2286">
         <PDBx:U11>0.4472</PDBx:U11>
         <PDBx:U12>0.0964</PDBx:U12>
         <PDBx:U13>0.0967</PDBx:U13>
         <PDBx:U22>0.3440</PDBx:U22>
         <PDBx:U23>-0.0095</PDBx:U23>
         <PDBx:U33>0.5333</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2287">
         <PDBx:U11>0.4358</PDBx:U11>
         <PDBx:U12>0.1155</PDBx:U12>
         <PDBx:U13>0.0751</PDBx:U13>
         <PDBx:U22>0.3768</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.5513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2288">
         <PDBx:U11>0.4414</PDBx:U11>
         <PDBx:U12>0.1378</PDBx:U12>
         <PDBx:U13>0.0717</PDBx:U13>
         <PDBx:U22>0.3866</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.5719</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2289">
         <PDBx:U11>0.4237</PDBx:U11>
         <PDBx:U12>0.0726</PDBx:U12>
         <PDBx:U13>0.1218</PDBx:U13>
         <PDBx:U22>0.3036</PDBx:U22>
         <PDBx:U23>-0.0242</PDBx:U23>
         <PDBx:U33>0.5180</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2290">
         <PDBx:U11>0.5133</PDBx:U11>
         <PDBx:U12>0.0516</PDBx:U12>
         <PDBx:U13>0.1453</PDBx:U13>
         <PDBx:U22>0.3562</PDBx:U22>
         <PDBx:U23>-0.0238</PDBx:U23>
         <PDBx:U33>0.5824</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2291">
         <PDBx:U11>0.6312</PDBx:U11>
         <PDBx:U12>0.0300</PDBx:U12>
         <PDBx:U13>0.1722</PDBx:U13>
         <PDBx:U22>0.4584</PDBx:U22>
         <PDBx:U23>-0.0356</PDBx:U23>
         <PDBx:U33>0.7088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2292">
         <PDBx:U11>0.6956</PDBx:U11>
         <PDBx:U12>-0.0026</PDBx:U12>
         <PDBx:U13>0.1714</PDBx:U13>
         <PDBx:U22>0.5493</PDBx:U22>
         <PDBx:U23>-0.0566</PDBx:U23>
         <PDBx:U33>0.7828</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2293">
         <PDBx:U11>0.8099</PDBx:U11>
         <PDBx:U12>-0.0293</PDBx:U12>
         <PDBx:U13>0.1999</PDBx:U13>
         <PDBx:U22>0.6489</PDBx:U22>
         <PDBx:U23>-0.0678</PDBx:U23>
         <PDBx:U33>0.9003</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>362</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>62</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2294">
         <PDBx:U11>0.3528</PDBx:U11>
         <PDBx:U12>0.1040</PDBx:U12>
         <PDBx:U13>0.0600</PDBx:U13>
         <PDBx:U22>0.3298</PDBx:U22>
         <PDBx:U23>-0.0223</PDBx:U23>
         <PDBx:U33>0.4769</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2295">
         <PDBx:U11>0.4201</PDBx:U11>
         <PDBx:U12>0.1140</PDBx:U12>
         <PDBx:U13>0.0407</PDBx:U13>
         <PDBx:U22>0.4454</PDBx:U22>
         <PDBx:U23>-0.0292</PDBx:U23>
         <PDBx:U33>0.5724</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2296">
         <PDBx:U11>0.3878</PDBx:U11>
         <PDBx:U12>0.1279</PDBx:U12>
         <PDBx:U13>0.0132</PDBx:U13>
         <PDBx:U22>0.4404</PDBx:U22>
         <PDBx:U23>-0.0174</PDBx:U23>
         <PDBx:U33>0.5256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2297">
         <PDBx:U11>0.4053</PDBx:U11>
         <PDBx:U12>0.1329</PDBx:U12>
         <PDBx:U13>-0.0040</PDBx:U13>
         <PDBx:U22>0.5021</PDBx:U22>
         <PDBx:U23>-0.0234</PDBx:U23>
         <PDBx:U33>0.5628</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2298">
         <PDBx:U11>0.4282</PDBx:U11>
         <PDBx:U12>0.0837</PDBx:U12>
         <PDBx:U13>0.0421</PDBx:U13>
         <PDBx:U22>0.4754</PDBx:U22>
         <PDBx:U23>-0.0524</PDBx:U23>
         <PDBx:U33>0.5922</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2299">
         <PDBx:U11>0.4940</PDBx:U11>
         <PDBx:U12>0.0650</PDBx:U12>
         <PDBx:U13>0.0660</PDBx:U13>
         <PDBx:U22>0.5202</PDBx:U22>
         <PDBx:U23>-0.0647</PDBx:U23>
         <PDBx:U33>0.6647</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2300">
         <PDBx:U11>0.5523</PDBx:U11>
         <PDBx:U12>0.0357</PDBx:U12>
         <PDBx:U13>0.0653</PDBx:U13>
         <PDBx:U22>0.5982</PDBx:U22>
         <PDBx:U23>-0.0841</PDBx:U23>
         <PDBx:U33>0.7274</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2301">
         <PDBx:U11>0.5940</PDBx:U11>
         <PDBx:U12>0.0421</PDBx:U12>
         <PDBx:U13>0.0506</PDBx:U13>
         <PDBx:U22>0.6776</PDBx:U22>
         <PDBx:U23>-0.0907</PDBx:U23>
         <PDBx:U33>0.7896</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2302">
         <PDBx:U11>0.5861</PDBx:U11>
         <PDBx:U12>0.0190</PDBx:U12>
         <PDBx:U13>0.0503</PDBx:U13>
         <PDBx:U22>0.6837</PDBx:U22>
         <PDBx:U23>-0.1072</PDBx:U23>
         <PDBx:U33>0.7846</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2303">
         <PDBx:U11>0.5324</PDBx:U11>
         <PDBx:U12>0.0230</PDBx:U12>
         <PDBx:U13>0.0391</PDBx:U13>
         <PDBx:U22>0.6612</PDBx:U22>
         <PDBx:U23>-0.1146</PDBx:U23>
         <PDBx:U33>0.7471</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2304">
         <PDBx:U11>0.6226</PDBx:U11>
         <PDBx:U12>-0.0093</PDBx:U12>
         <PDBx:U13>0.0615</PDBx:U13>
         <PDBx:U22>0.7019</PDBx:U22>
         <PDBx:U23>-0.1161</PDBx:U23>
         <PDBx:U33>0.8040</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>363</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>63</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2305">
         <PDBx:U11>0.3691</PDBx:U11>
         <PDBx:U12>0.1289</PDBx:U12>
         <PDBx:U13>0.0115</PDBx:U13>
         <PDBx:U22>0.3951</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.4705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2306">
         <PDBx:U11>0.3232</PDBx:U11>
         <PDBx:U12>0.1414</PDBx:U12>
         <PDBx:U13>-0.0109</PDBx:U13>
         <PDBx:U22>0.3680</PDBx:U22>
         <PDBx:U23>0.0097</PDBx:U23>
         <PDBx:U33>0.4040</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2307">
         <PDBx:U11>0.3667</PDBx:U11>
         <PDBx:U12>0.1681</PDBx:U12>
         <PDBx:U13>-0.0182</PDBx:U13>
         <PDBx:U22>0.4117</PDBx:U22>
         <PDBx:U23>0.0279</PDBx:U23>
         <PDBx:U33>0.4500</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2308">
         <PDBx:U11>0.3941</PDBx:U11>
         <PDBx:U12>0.1783</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.3965</PDBx:U22>
         <PDBx:U23>0.0421</PDBx:U23>
         <PDBx:U33>0.4636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2309">
         <PDBx:U11>0.3535</PDBx:U11>
         <PDBx:U12>0.1298</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.3660</PDBx:U22>
         <PDBx:U23>0.0185</PDBx:U23>
         <PDBx:U33>0.3936</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2310">
         <PDBx:U11>0.3572</PDBx:U11>
         <PDBx:U12>0.1429</PDBx:U12>
         <PDBx:U13>-0.0263</PDBx:U13>
         <PDBx:U22>0.3831</PDBx:U22>
         <PDBx:U23>0.0315</PDBx:U23>
         <PDBx:U33>0.3708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2311">
         <PDBx:U11>0.3147</PDBx:U11>
         <PDBx:U12>0.0989</PDBx:U12>
         <PDBx:U13>-0.0030</PDBx:U13>
         <PDBx:U22>0.3319</PDBx:U22>
         <PDBx:U23>0.0024</PDBx:U23>
         <PDBx:U33>0.3541</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>364</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>64</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2312">
         <PDBx:U11>0.4391</PDBx:U11>
         <PDBx:U12>0.1739</PDBx:U12>
         <PDBx:U13>-0.0394</PDBx:U13>
         <PDBx:U22>0.5311</PDBx:U22>
         <PDBx:U23>0.0261</PDBx:U23>
         <PDBx:U33>0.5385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2313">
         <PDBx:U11>0.4942</PDBx:U11>
         <PDBx:U12>0.1971</PDBx:U12>
         <PDBx:U13>-0.0495</PDBx:U13>
         <PDBx:U22>0.5948</PDBx:U22>
         <PDBx:U23>0.0426</PDBx:U23>
         <PDBx:U33>0.6007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2314">
         <PDBx:U11>0.5632</PDBx:U11>
         <PDBx:U12>0.2107</PDBx:U12>
         <PDBx:U13>-0.0469</PDBx:U13>
         <PDBx:U22>0.6215</PDBx:U22>
         <PDBx:U23>0.0667</PDBx:U23>
         <PDBx:U33>0.6269</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2315">
         <PDBx:U11>0.5724</PDBx:U11>
         <PDBx:U12>0.2026</PDBx:U12>
         <PDBx:U13>-0.0525</PDBx:U13>
         <PDBx:U22>0.6230</PDBx:U22>
         <PDBx:U23>0.0711</PDBx:U23>
         <PDBx:U33>0.5981</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2316">
         <PDBx:U11>0.5016</PDBx:U11>
         <PDBx:U12>0.1922</PDBx:U12>
         <PDBx:U13>-0.0742</PDBx:U13>
         <PDBx:U22>0.6594</PDBx:U22>
         <PDBx:U23>0.0353</PDBx:U23>
         <PDBx:U33>0.6137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2317">
         <PDBx:U11>0.4874</PDBx:U11>
         <PDBx:U12>0.1671</PDBx:U12>
         <PDBx:U13>-0.0702</PDBx:U13>
         <PDBx:U22>0.6673</PDBx:U22>
         <PDBx:U23>0.0095</PDBx:U23>
         <PDBx:U33>0.6162</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2318">
         <PDBx:U11>0.3984</PDBx:U11>
         <PDBx:U12>0.1558</PDBx:U12>
         <PDBx:U13>-0.0536</PDBx:U13>
         <PDBx:U22>0.5368</PDBx:U22>
         <PDBx:U23>0.0070</PDBx:U23>
         <PDBx:U33>0.5076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>365</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>65</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2319">
         <PDBx:U11>0.5559</PDBx:U11>
         <PDBx:U12>0.2298</PDBx:U12>
         <PDBx:U13>-0.0359</PDBx:U13>
         <PDBx:U22>0.5844</PDBx:U22>
         <PDBx:U23>0.0806</PDBx:U23>
         <PDBx:U33>0.6251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2320">
         <PDBx:U11>0.6293</PDBx:U11>
         <PDBx:U12>0.2427</PDBx:U12>
         <PDBx:U13>-0.0302</PDBx:U13>
         <PDBx:U22>0.6149</PDBx:U22>
         <PDBx:U23>0.1039</PDBx:U23>
         <PDBx:U33>0.6569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2321">
         <PDBx:U11>0.6421</PDBx:U11>
         <PDBx:U12>0.2318</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.5655</PDBx:U22>
         <PDBx:U23>0.1047</PDBx:U23>
         <PDBx:U33>0.6452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2322">
         <PDBx:U11>0.6688</PDBx:U11>
         <PDBx:U12>0.2422</PDBx:U12>
         <PDBx:U13>0.0147</PDBx:U13>
         <PDBx:U22>0.5490</PDBx:U22>
         <PDBx:U23>0.1216</PDBx:U23>
         <PDBx:U33>0.6450</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>366</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>66</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2323">
         <PDBx:U11>0.5545</PDBx:U11>
         <PDBx:U12>0.2092</PDBx:U12>
         <PDBx:U13>0.0131</PDBx:U13>
         <PDBx:U22>0.4743</PDBx:U22>
         <PDBx:U23>0.0858</PDBx:U23>
         <PDBx:U33>0.5666</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2324">
         <PDBx:U11>0.5414</PDBx:U11>
         <PDBx:U12>0.1920</PDBx:U12>
         <PDBx:U13>0.0422</PDBx:U13>
         <PDBx:U22>0.4099</PDBx:U22>
         <PDBx:U23>0.0829</PDBx:U23>
         <PDBx:U33>0.5311</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2325">
         <PDBx:U11>0.5183</PDBx:U11>
         <PDBx:U12>0.1961</PDBx:U12>
         <PDBx:U13>0.0694</PDBx:U13>
         <PDBx:U22>0.3474</PDBx:U22>
         <PDBx:U23>0.0852</PDBx:U23>
         <PDBx:U33>0.5152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2326">
         <PDBx:U11>0.5648</PDBx:U11>
         <PDBx:U12>0.1920</PDBx:U12>
         <PDBx:U13>0.0915</PDBx:U13>
         <PDBx:U22>0.3479</PDBx:U22>
         <PDBx:U23>0.0935</PDBx:U23>
         <PDBx:U33>0.5315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2327">
         <PDBx:U11>0.5345</PDBx:U11>
         <PDBx:U12>0.1666</PDBx:U12>
         <PDBx:U13>0.0474</PDBx:U13>
         <PDBx:U22>0.4144</PDBx:U22>
         <PDBx:U23>0.0617</PDBx:U23>
         <PDBx:U33>0.5362</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2328">
         <PDBx:U11>0.5168</PDBx:U11>
         <PDBx:U12>0.1443</PDBx:U12>
         <PDBx:U13>0.0733</PDBx:U13>
         <PDBx:U22>0.3542</PDBx:U22>
         <PDBx:U23>0.0570</PDBx:U23>
         <PDBx:U33>0.4952</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2329">
         <PDBx:U11>0.4746</PDBx:U11>
         <PDBx:U12>0.1381</PDBx:U12>
         <PDBx:U13>0.0730</PDBx:U13>
         <PDBx:U22>0.2955</PDBx:U22>
         <PDBx:U23>0.0639</PDBx:U23>
         <PDBx:U33>0.4180</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2330">
         <PDBx:U11>0.5525</PDBx:U11>
         <PDBx:U12>0.1260</PDBx:U12>
         <PDBx:U13>0.0986</PDBx:U13>
         <PDBx:U22>0.3703</PDBx:U22>
         <PDBx:U23>0.0432</PDBx:U23>
         <PDBx:U33>0.5446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2331">
         <PDBx:U11>0.4681</PDBx:U11>
         <PDBx:U12>0.1150</PDBx:U12>
         <PDBx:U13>0.0971</PDBx:U13>
         <PDBx:U22>0.2567</PDBx:U22>
         <PDBx:U23>0.0565</PDBx:U23>
         <PDBx:U33>0.3956</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2332">
         <PDBx:U11>0.5055</PDBx:U11>
         <PDBx:U12>0.1010</PDBx:U12>
         <PDBx:U13>0.1212</PDBx:U13>
         <PDBx:U22>0.2944</PDBx:U22>
         <PDBx:U23>0.0358</PDBx:U23>
         <PDBx:U33>0.4790</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2333">
         <PDBx:U11>0.4827</PDBx:U11>
         <PDBx:U12>0.0960</PDBx:U12>
         <PDBx:U13>0.1203</PDBx:U13>
         <PDBx:U22>0.2587</PDBx:U22>
         <PDBx:U23>0.0420</PDBx:U23>
         <PDBx:U33>0.4265</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>367</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>67</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2334">
         <PDBx:U11>0.5509</PDBx:U11>
         <PDBx:U12>0.2026</PDBx:U12>
         <PDBx:U13>0.0703</PDBx:U13>
         <PDBx:U22>0.3982</PDBx:U22>
         <PDBx:U23>0.0759</PDBx:U23>
         <PDBx:U33>0.5872</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2335">
         <PDBx:U11>0.6761</PDBx:U11>
         <PDBx:U12>0.2054</PDBx:U12>
         <PDBx:U13>0.0983</PDBx:U13>
         <PDBx:U22>0.4869</PDBx:U22>
         <PDBx:U23>0.0762</PDBx:U23>
         <PDBx:U33>0.7204</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2336">
         <PDBx:U11>0.7042</PDBx:U11>
         <PDBx:U12>0.2364</PDBx:U12>
         <PDBx:U13>0.0974</PDBx:U13>
         <PDBx:U22>0.4957</PDBx:U22>
         <PDBx:U23>0.1007</PDBx:U23>
         <PDBx:U33>0.7385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2337">
         <PDBx:U11>0.7050</PDBx:U11>
         <PDBx:U12>0.2430</PDBx:U12>
         <PDBx:U13>0.1226</PDBx:U13>
         <PDBx:U22>0.4615</PDBx:U22>
         <PDBx:U23>0.1047</PDBx:U23>
         <PDBx:U33>0.7427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2338">
         <PDBx:U11>0.6642</PDBx:U11>
         <PDBx:U12>0.2002</PDBx:U12>
         <PDBx:U13>0.1030</PDBx:U13>
         <PDBx:U22>0.4984</PDBx:U22>
         <PDBx:U23>0.0560</PDBx:U23>
         <PDBx:U33>0.7523</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2339">
         <PDBx:U11>0.6371</PDBx:U11>
         <PDBx:U12>0.1656</PDBx:U12>
         <PDBx:U13>0.1123</PDBx:U13>
         <PDBx:U22>0.4780</PDBx:U22>
         <PDBx:U23>0.0330</PDBx:U23>
         <PDBx:U33>0.7277</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2340">
         <PDBx:U11>0.6233</PDBx:U11>
         <PDBx:U12>0.2218</PDBx:U12>
         <PDBx:U13>0.0722</PDBx:U13>
         <PDBx:U22>0.5124</PDBx:U22>
         <PDBx:U23>0.0551</PDBx:U23>
         <PDBx:U33>0.7460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>368</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>68</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2341">
         <PDBx:U11>0.7279</PDBx:U11>
         <PDBx:U12>0.2544</PDBx:U12>
         <PDBx:U13>0.0693</PDBx:U13>
         <PDBx:U22>0.5429</PDBx:U22>
         <PDBx:U23>0.1170</PDBx:U23>
         <PDBx:U33>0.7488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2342">
         <PDBx:U11>0.7799</PDBx:U11>
         <PDBx:U12>0.2835</PDBx:U12>
         <PDBx:U13>0.0655</PDBx:U13>
         <PDBx:U22>0.5772</PDBx:U22>
         <PDBx:U23>0.1431</PDBx:U23>
         <PDBx:U33>0.7841</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2343">
         <PDBx:U11>0.7907</PDBx:U11>
         <PDBx:U12>0.2765</PDBx:U12>
         <PDBx:U13>0.0892</PDBx:U13>
         <PDBx:U22>0.5300</PDBx:U22>
         <PDBx:U23>0.1553</PDBx:U23>
         <PDBx:U33>0.7428</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2344">
         <PDBx:U11>0.8730</PDBx:U11>
         <PDBx:U12>0.2972</PDBx:U12>
         <PDBx:U13>0.0981</PDBx:U13>
         <PDBx:U22>0.5795</PDBx:U22>
         <PDBx:U23>0.1764</PDBx:U23>
         <PDBx:U33>0.8042</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2345">
         <PDBx:U11>0.7973</PDBx:U11>
         <PDBx:U12>0.3002</PDBx:U12>
         <PDBx:U13>0.0264</PDBx:U13>
         <PDBx:U22>0.6456</PDBx:U22>
         <PDBx:U23>0.1546</PDBx:U23>
         <PDBx:U33>0.8028</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2346">
         <PDBx:U11>0.8007</PDBx:U11>
         <PDBx:U12>0.3090</PDBx:U12>
         <PDBx:U13>0.0047</PDBx:U13>
         <PDBx:U22>0.7090</PDBx:U22>
         <PDBx:U23>0.1425</PDBx:U23>
         <PDBx:U33>0.8611</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2347">
         <PDBx:U11>0.8183</PDBx:U11>
         <PDBx:U12>0.3163</PDBx:U12>
         <PDBx:U13>0.0189</PDBx:U13>
         <PDBx:U22>0.7213</PDBx:U22>
         <PDBx:U23>0.1343</PDBx:U23>
         <PDBx:U33>0.9152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2348">
         <PDBx:U11>0.7774</PDBx:U11>
         <PDBx:U12>0.3065</PDBx:U12>
         <PDBx:U13>-0.0242</PDBx:U13>
         <PDBx:U22>0.7386</PDBx:U22>
         <PDBx:U23>0.1393</PDBx:U23>
         <PDBx:U33>0.8444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>369</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>69</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2349">
         <PDBx:U11>0.6975</PDBx:U11>
         <PDBx:U12>0.2472</PDBx:U12>
         <PDBx:U13>0.1003</PDBx:U13>
         <PDBx:U22>0.4252</PDBx:U22>
         <PDBx:U23>0.1413</PDBx:U23>
         <PDBx:U33>0.6300</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2350">
         <PDBx:U11>0.7420</PDBx:U11>
         <PDBx:U12>0.2351</PDBx:U12>
         <PDBx:U13>0.1248</PDBx:U13>
         <PDBx:U22>0.4196</PDBx:U22>
         <PDBx:U23>0.1467</PDBx:U23>
         <PDBx:U33>0.6287</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2351">
         <PDBx:U11>0.8168</PDBx:U11>
         <PDBx:U12>0.2215</PDBx:U12>
         <PDBx:U13>0.1664</PDBx:U13>
         <PDBx:U22>0.4492</PDBx:U22>
         <PDBx:U23>0.1380</PDBx:U23>
         <PDBx:U33>0.7044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2352">
         <PDBx:U11>0.7583</PDBx:U11>
         <PDBx:U12>0.2094</PDBx:U12>
         <PDBx:U13>0.1762</PDBx:U13>
         <PDBx:U22>0.4013</PDBx:U22>
         <PDBx:U23>0.1214</PDBx:U23>
         <PDBx:U33>0.6792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2353">
         <PDBx:U11>0.6627</PDBx:U11>
         <PDBx:U12>0.2090</PDBx:U12>
         <PDBx:U13>0.1190</PDBx:U13>
         <PDBx:U22>0.3517</PDBx:U22>
         <PDBx:U23>0.1335</PDBx:U23>
         <PDBx:U33>0.5327</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2354">
         <PDBx:U11>0.6498</PDBx:U11>
         <PDBx:U12>0.2151</PDBx:U12>
         <PDBx:U13>0.0820</PDBx:U13>
         <PDBx:U22>0.3852</PDBx:U22>
         <PDBx:U23>0.1371</PDBx:U23>
         <PDBx:U33>0.5178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2355">
         <PDBx:U11>0.6193</PDBx:U11>
         <PDBx:U12>0.1884</PDBx:U12>
         <PDBx:U13>0.0823</PDBx:U13>
         <PDBx:U22>0.3610</PDBx:U22>
         <PDBx:U23>0.1219</PDBx:U23>
         <PDBx:U33>0.4761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2356">
         <PDBx:U11>0.6779</PDBx:U11>
         <PDBx:U12>0.2357</PDBx:U12>
         <PDBx:U13>0.0684</PDBx:U13>
         <PDBx:U22>0.4058</PDBx:U22>
         <PDBx:U23>0.1603</PDBx:U23>
         <PDBx:U33>0.5119</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>370</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>70</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2357">
         <PDBx:U11>0.8873</PDBx:U11>
         <PDBx:U12>0.2212</PDBx:U12>
         <PDBx:U13>0.1926</PDBx:U13>
         <PDBx:U22>0.4695</PDBx:U22>
         <PDBx:U23>0.1476</PDBx:U23>
         <PDBx:U33>0.7365</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2358">
         <PDBx:U11>0.8926</PDBx:U11>
         <PDBx:U12>0.2030</PDBx:U12>
         <PDBx:U13>0.2366</PDBx:U13>
         <PDBx:U22>0.4318</PDBx:U22>
         <PDBx:U23>0.1368</PDBx:U23>
         <PDBx:U33>0.7369</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2359">
         <PDBx:U11>0.8499</PDBx:U11>
         <PDBx:U12>0.1636</PDBx:U12>
         <PDBx:U13>0.2469</PDBx:U13>
         <PDBx:U22>0.4045</PDBx:U22>
         <PDBx:U23>0.1091</PDBx:U23>
         <PDBx:U33>0.7045</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2360">
         <PDBx:U11>0.7822</PDBx:U11>
         <PDBx:U12>0.1522</PDBx:U12>
         <PDBx:U13>0.2255</PDBx:U13>
         <PDBx:U22>0.3646</PDBx:U22>
         <PDBx:U23>0.1023</PDBx:U23>
         <PDBx:U33>0.6337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2361">
         <PDBx:U11>0.9837</PDBx:U11>
         <PDBx:U12>0.2063</PDBx:U12>
         <PDBx:U13>0.2643</PDBx:U13>
         <PDBx:U22>0.4671</PDBx:U22>
         <PDBx:U23>0.1487</PDBx:U23>
         <PDBx:U33>0.7802</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2362">
         <PDBx:U11>0.9560</PDBx:U11>
         <PDBx:U12>0.1876</PDBx:U12>
         <PDBx:U13>0.2597</PDBx:U13>
         <PDBx:U22>0.4404</PDBx:U22>
         <PDBx:U23>0.1414</PDBx:U23>
         <PDBx:U33>0.7233</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2363">
         <PDBx:U11>0.9545</PDBx:U11>
         <PDBx:U12>0.2463</PDBx:U12>
         <PDBx:U13>0.2506</PDBx:U13>
         <PDBx:U22>0.4234</PDBx:U22>
         <PDBx:U23>0.1793</PDBx:U23>
         <PDBx:U33>0.7363</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>371</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>71</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2364">
         <PDBx:U11>0.8332</PDBx:U11>
         <PDBx:U12>0.0695</PDBx:U12>
         <PDBx:U13>0.1190</PDBx:U13>
         <PDBx:U22>0.3373</PDBx:U22>
         <PDBx:U23>0.0528</PDBx:U23>
         <PDBx:U33>0.8460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2365">
         <PDBx:U11>0.8101</PDBx:U11>
         <PDBx:U12>0.0552</PDBx:U12>
         <PDBx:U13>0.1469</PDBx:U13>
         <PDBx:U22>0.3301</PDBx:U22>
         <PDBx:U23>0.0280</PDBx:U23>
         <PDBx:U33>0.7934</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2366">
         <PDBx:U11>0.8243</PDBx:U11>
         <PDBx:U12>0.0241</PDBx:U12>
         <PDBx:U13>0.1379</PDBx:U13>
         <PDBx:U22>0.3384</PDBx:U22>
         <PDBx:U23>0.0180</PDBx:U23>
         <PDBx:U33>0.7516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2367">
         <PDBx:U11>0.7695</PDBx:U11>
         <PDBx:U12>0.0115</PDBx:U12>
         <PDBx:U13>0.1428</PDBx:U13>
         <PDBx:U22>0.3122</PDBx:U22>
         <PDBx:U23>0.0062</PDBx:U23>
         <PDBx:U33>0.6872</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2368">
         <PDBx:U11>0.8594</PDBx:U11>
         <PDBx:U12>0.0597</PDBx:U12>
         <PDBx:U13>0.1772</PDBx:U13>
         <PDBx:U22>0.3552</PDBx:U22>
         <PDBx:U23>0.0100</PDBx:U23>
         <PDBx:U33>0.8240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2369">
         <PDBx:U11>0.8456</PDBx:U11>
         <PDBx:U12>0.0447</PDBx:U12>
         <PDBx:U13>0.2008</PDBx:U13>
         <PDBx:U22>0.3480</PDBx:U22>
         <PDBx:U23>-0.0162</PDBx:U23>
         <PDBx:U33>0.7707</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2370">
         <PDBx:U11>0.8036</PDBx:U11>
         <PDBx:U12>0.0468</PDBx:U12>
         <PDBx:U13>0.2047</PDBx:U13>
         <PDBx:U22>0.3504</PDBx:U22>
         <PDBx:U23>-0.0179</PDBx:U23>
         <PDBx:U33>0.7498</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2371">
         <PDBx:U11>0.9301</PDBx:U11>
         <PDBx:U12>0.0561</PDBx:U12>
         <PDBx:U13>0.2276</PDBx:U13>
         <PDBx:U22>0.4066</PDBx:U22>
         <PDBx:U23>-0.0268</PDBx:U23>
         <PDBx:U33>0.8457</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>372</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>72</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2372">
         <PDBx:U11>0.8608</PDBx:U11>
         <PDBx:U12>0.0117</PDBx:U12>
         <PDBx:U13>0.1254</PDBx:U13>
         <PDBx:U22>0.3400</PDBx:U22>
         <PDBx:U23>0.0228</PDBx:U23>
         <PDBx:U33>0.7542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2373">
         <PDBx:U11>0.8421</PDBx:U11>
         <PDBx:U12>-0.0179</PDBx:U12>
         <PDBx:U13>0.1210</PDBx:U13>
         <PDBx:U22>0.3203</PDBx:U22>
         <PDBx:U23>0.0143</PDBx:U23>
         <PDBx:U33>0.6880</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2374">
         <PDBx:U11>0.8451</PDBx:U11>
         <PDBx:U12>-0.0179</PDBx:U12>
         <PDBx:U13>0.1212</PDBx:U13>
         <PDBx:U22>0.3238</PDBx:U22>
         <PDBx:U23>0.0140</PDBx:U23>
         <PDBx:U33>0.6912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2375">
         <PDBx:U11>0.7287</PDBx:U11>
         <PDBx:U12>-0.0253</PDBx:U12>
         <PDBx:U13>0.1021</PDBx:U13>
         <PDBx:U22>0.2345</PDBx:U22>
         <PDBx:U23>0.0240</PDBx:U23>
         <PDBx:U33>0.5771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2376">
         <PDBx:U11>0.6819</PDBx:U11>
         <PDBx:U12>-0.0456</PDBx:U12>
         <PDBx:U13>0.1070</PDBx:U13>
         <PDBx:U22>0.2106</PDBx:U22>
         <PDBx:U23>0.0103</PDBx:U23>
         <PDBx:U33>0.5089</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2377">
         <PDBx:U11>0.9016</PDBx:U11>
         <PDBx:U12>-0.0264</PDBx:U12>
         <PDBx:U13>0.1134</PDBx:U13>
         <PDBx:U22>0.3369</PDBx:U22>
         <PDBx:U23>0.0219</PDBx:U23>
         <PDBx:U33>0.7156</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2378">
         <PDBx:U11>0.8989</PDBx:U11>
         <PDBx:U12>-0.0273</PDBx:U12>
         <PDBx:U13>0.1146</PDBx:U13>
         <PDBx:U22>0.3350</PDBx:U22>
         <PDBx:U23>0.0206</PDBx:U23>
         <PDBx:U33>0.7118</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2379">
         <PDBx:U11>0.9032</PDBx:U11>
         <PDBx:U12>-0.0555</PDBx:U12>
         <PDBx:U13>0.1172</PDBx:U13>
         <PDBx:U22>0.3396</PDBx:U22>
         <PDBx:U23>0.0119</PDBx:U23>
         <PDBx:U33>0.6734</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2380">
         <PDBx:U11>0.9704</PDBx:U11>
         <PDBx:U12>-0.0325</PDBx:U12>
         <PDBx:U13>0.1356</PDBx:U13>
         <PDBx:U22>0.3816</PDBx:U22>
         <PDBx:U23>0.0041</PDBx:U23>
         <PDBx:U33>0.7641</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2381">
         <PDBx:U11>0.9249</PDBx:U11>
         <PDBx:U12>-0.0663</PDBx:U12>
         <PDBx:U13>0.1019</PDBx:U13>
         <PDBx:U22>0.3632</PDBx:U22>
         <PDBx:U23>0.0231</PDBx:U23>
         <PDBx:U33>0.6740</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2382">
         <PDBx:U11>1.0150</PDBx:U11>
         <PDBx:U12>-0.0583</PDBx:U12>
         <PDBx:U13>0.1472</PDBx:U13>
         <PDBx:U22>0.4276</PDBx:U22>
         <PDBx:U23>-0.0135</PDBx:U23>
         <PDBx:U33>0.7751</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2383">
         <PDBx:U11>0.9161</PDBx:U11>
         <PDBx:U12>-0.0751</PDBx:U12>
         <PDBx:U13>0.1352</PDBx:U13>
         <PDBx:U22>0.3536</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.6637</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2384">
         <PDBx:U11>1.0445</PDBx:U11>
         <PDBx:U12>-0.0151</PDBx:U12>
         <PDBx:U13>0.1463</PDBx:U13>
         <PDBx:U22>0.4292</PDBx:U22>
         <PDBx:U23>0.0029</PDBx:U23>
         <PDBx:U33>0.8502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2385">
         <PDBx:U11>0.9202</PDBx:U11>
         <PDBx:U12>-0.0898</PDBx:U12>
         <PDBx:U13>0.1153</PDBx:U13>
         <PDBx:U22>0.3616</PDBx:U22>
         <PDBx:U23>0.0098</PDBx:U23>
         <PDBx:U33>0.6379</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2386">
         <PDBx:U11>1.0614</PDBx:U11>
         <PDBx:U12>-0.0581</PDBx:U12>
         <PDBx:U13>0.1613</PDBx:U13>
         <PDBx:U22>0.4470</PDBx:U22>
         <PDBx:U23>-0.0242</PDBx:U23>
         <PDBx:U33>0.8106</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2387">
         <PDBx:U11>0.9211</PDBx:U11>
         <PDBx:U12>-0.0958</PDBx:U12>
         <PDBx:U13>0.1336</PDBx:U13>
         <PDBx:U22>0.3646</PDBx:U22>
         <PDBx:U23>-0.0082</PDBx:U23>
         <PDBx:U33>0.6426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2388">
         <PDBx:U11>1.0823</PDBx:U11>
         <PDBx:U12>-0.0320</PDBx:U12>
         <PDBx:U13>0.1624</PDBx:U13>
         <PDBx:U22>0.4484</PDBx:U22>
         <PDBx:U23>-0.0153</PDBx:U23>
         <PDBx:U33>0.8547</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>373</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>73</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2389">
         <PDBx:U11>0.7165</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>0.0780</PDBx:U13>
         <PDBx:U22>0.2208</PDBx:U22>
         <PDBx:U23>0.0480</PDBx:U23>
         <PDBx:U33>0.5941</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2390">
         <PDBx:U11>0.7272</PDBx:U11>
         <PDBx:U12>-0.0150</PDBx:U12>
         <PDBx:U13>0.0560</PDBx:U13>
         <PDBx:U22>0.2523</PDBx:U22>
         <PDBx:U23>0.0592</PDBx:U23>
         <PDBx:U33>0.6037</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2391">
         <PDBx:U11>0.6722</PDBx:U11>
         <PDBx:U12>-0.0119</PDBx:U12>
         <PDBx:U13>0.0675</PDBx:U13>
         <PDBx:U22>0.2414</PDBx:U22>
         <PDBx:U23>0.0497</PDBx:U23>
         <PDBx:U33>0.5778</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2392">
         <PDBx:U11>0.5659</PDBx:U11>
         <PDBx:U12>-0.0272</PDBx:U12>
         <PDBx:U13>0.0604</PDBx:U13>
         <PDBx:U22>0.1644</PDBx:U22>
         <PDBx:U23>0.0439</PDBx:U23>
         <PDBx:U33>0.4559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2393">
         <PDBx:U11>0.7658</PDBx:U11>
         <PDBx:U12>0.0016</PDBx:U12>
         <PDBx:U13>0.0208</PDBx:U13>
         <PDBx:U22>0.2779</PDBx:U22>
         <PDBx:U23>0.0887</PDBx:U23>
         <PDBx:U33>0.6699</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2394">
         <PDBx:U11>0.8706</PDBx:U11>
         <PDBx:U12>-0.0051</PDBx:U12>
         <PDBx:U13>0.0076</PDBx:U13>
         <PDBx:U22>0.3419</PDBx:U22>
         <PDBx:U23>0.0993</PDBx:U23>
         <PDBx:U33>0.7373</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2395">
         <PDBx:U11>0.8955</PDBx:U11>
         <PDBx:U12>-0.0256</PDBx:U12>
         <PDBx:U13>0.0241</PDBx:U13>
         <PDBx:U22>0.3494</PDBx:U22>
         <PDBx:U23>0.0845</PDBx:U23>
         <PDBx:U33>0.7088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2396">
         <PDBx:U11>0.9282</PDBx:U11>
         <PDBx:U12>0.0109</PDBx:U12>
         <PDBx:U13>-0.0160</PDBx:U13>
         <PDBx:U22>0.3865</PDBx:U22>
         <PDBx:U23>0.1221</PDBx:U23>
         <PDBx:U33>0.8196</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>374</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>74</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2397">
         <PDBx:U11>0.6378</PDBx:U11>
         <PDBx:U12>0.0088</PDBx:U12>
         <PDBx:U13>0.0840</PDBx:U13>
         <PDBx:U22>0.2269</PDBx:U22>
         <PDBx:U23>0.0465</PDBx:U23>
         <PDBx:U33>0.5911</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2398">
         <PDBx:U11>0.5723</PDBx:U11>
         <PDBx:U12>0.0125</PDBx:U12>
         <PDBx:U13>0.0947</PDBx:U13>
         <PDBx:U22>0.2167</PDBx:U22>
         <PDBx:U23>0.0358</PDBx:U23>
         <PDBx:U33>0.5554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2399">
         <PDBx:U11>0.5476</PDBx:U11>
         <PDBx:U12>-0.0110</PDBx:U12>
         <PDBx:U13>0.1091</PDBx:U13>
         <PDBx:U22>0.2028</PDBx:U22>
         <PDBx:U23>0.0098</PDBx:U23>
         <PDBx:U33>0.4865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2400">
         <PDBx:U11>0.4701</PDBx:U11>
         <PDBx:U12>-0.0193</PDBx:U12>
         <PDBx:U13>0.1025</PDBx:U13>
         <PDBx:U22>0.1665</PDBx:U22>
         <PDBx:U23>0.0044</PDBx:U23>
         <PDBx:U33>0.4115</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2401">
         <PDBx:U11>0.5337</PDBx:U11>
         <PDBx:U12>0.0373</PDBx:U12>
         <PDBx:U13>0.1197</PDBx:U13>
         <PDBx:U22>0.1822</PDBx:U22>
         <PDBx:U23>0.0348</PDBx:U23>
         <PDBx:U33>0.5622</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2402">
         <PDBx:U11>0.6168</PDBx:U11>
         <PDBx:U12>0.0629</PDBx:U12>
         <PDBx:U13>0.1057</PDBx:U13>
         <PDBx:U22>0.2684</PDBx:U22>
         <PDBx:U23>0.0607</PDBx:U23>
         <PDBx:U33>0.7114</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2403">
         <PDBx:U11>0.6328</PDBx:U11>
         <PDBx:U12>0.0849</PDBx:U12>
         <PDBx:U13>0.1350</PDBx:U13>
         <PDBx:U22>0.2988</PDBx:U22>
         <PDBx:U23>0.0563</PDBx:U23>
         <PDBx:U33>0.7708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2404">
         <PDBx:U11>0.6071</PDBx:U11>
         <PDBx:U12>0.0833</PDBx:U12>
         <PDBx:U13>0.1665</PDBx:U13>
         <PDBx:U22>0.2787</PDBx:U22>
         <PDBx:U23>0.0374</PDBx:U23>
         <PDBx:U33>0.7276</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2405">
         <PDBx:U11>0.6931</PDBx:U11>
         <PDBx:U12>0.1039</PDBx:U12>
         <PDBx:U13>0.1242</PDBx:U13>
         <PDBx:U22>0.3624</PDBx:U22>
         <PDBx:U23>0.0733</PDBx:U23>
         <PDBx:U33>0.8823</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>375</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>75</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2406">
         <PDBx:U11>0.5827</PDBx:U11>
         <PDBx:U12>-0.0216</PDBx:U12>
         <PDBx:U13>0.1267</PDBx:U13>
         <PDBx:U22>0.1994</PDBx:U22>
         <PDBx:U23>-0.0058</PDBx:U23>
         <PDBx:U33>0.4853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2407">
         <PDBx:U11>0.5785</PDBx:U11>
         <PDBx:U12>-0.0456</PDBx:U12>
         <PDBx:U13>0.1360</PDBx:U13>
         <PDBx:U22>0.2026</PDBx:U22>
         <PDBx:U23>-0.0301</PDBx:U23>
         <PDBx:U33>0.4472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2408">
         <PDBx:U11>0.6262</PDBx:U11>
         <PDBx:U12>-0.0665</PDBx:U12>
         <PDBx:U13>0.1212</PDBx:U13>
         <PDBx:U22>0.2680</PDBx:U22>
         <PDBx:U23>-0.0287</PDBx:U23>
         <PDBx:U33>0.4787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2409">
         <PDBx:U11>0.5786</PDBx:U11>
         <PDBx:U12>-0.0772</PDBx:U12>
         <PDBx:U13>0.1198</PDBx:U13>
         <PDBx:U22>0.2590</PDBx:U22>
         <PDBx:U23>-0.0411</PDBx:U23>
         <PDBx:U33>0.4337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2410">
         <PDBx:U11>0.6522</PDBx:U11>
         <PDBx:U12>-0.0541</PDBx:U12>
         <PDBx:U13>0.1468</PDBx:U13>
         <PDBx:U22>0.2477</PDBx:U22>
         <PDBx:U23>-0.0420</PDBx:U23>
         <PDBx:U33>0.4932</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2411">
         <PDBx:U11>0.6458</PDBx:U11>
         <PDBx:U12>-0.0792</PDBx:U12>
         <PDBx:U13>0.1470</PDBx:U13>
         <PDBx:U22>0.2640</PDBx:U22>
         <PDBx:U23>-0.0611</PDBx:U23>
         <PDBx:U33>0.4670</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2412">
         <PDBx:U11>0.6283</PDBx:U11>
         <PDBx:U12>-0.0355</PDBx:U12>
         <PDBx:U13>0.1646</PDBx:U13>
         <PDBx:U22>0.2070</PDBx:U22>
         <PDBx:U23>-0.0476</PDBx:U23>
         <PDBx:U33>0.4765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>376</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>76</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2413">
         <PDBx:U11>0.6126</PDBx:U11>
         <PDBx:U12>-0.0696</PDBx:U12>
         <PDBx:U13>0.1090</PDBx:U13>
         <PDBx:U22>0.2297</PDBx:U22>
         <PDBx:U23>-0.0131</PDBx:U23>
         <PDBx:U33>0.4482</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2414">
         <PDBx:U11>0.5828</PDBx:U11>
         <PDBx:U12>-0.0869</PDBx:U12>
         <PDBx:U13>0.0997</PDBx:U13>
         <PDBx:U22>0.2102</PDBx:U22>
         <PDBx:U23>-0.0114</PDBx:U23>
         <PDBx:U33>0.3951</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2415">
         <PDBx:U11>0.5554</PDBx:U11>
         <PDBx:U12>-0.0863</PDBx:U12>
         <PDBx:U13>0.0876</PDBx:U13>
         <PDBx:U22>0.2143</PDBx:U22>
         <PDBx:U23>-0.0070</PDBx:U23>
         <PDBx:U33>0.3820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2416">
         <PDBx:U11>0.5567</PDBx:U11>
         <PDBx:U12>-0.1001</PDBx:U12>
         <PDBx:U13>0.0908</PDBx:U13>
         <PDBx:U22>0.2461</PDBx:U22>
         <PDBx:U23>-0.0192</PDBx:U23>
         <PDBx:U33>0.3787</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2417">
         <PDBx:U11>0.6884</PDBx:U11>
         <PDBx:U12>-0.0862</PDBx:U12>
         <PDBx:U13>0.0869</PDBx:U13>
         <PDBx:U22>0.2756</PDBx:U22>
         <PDBx:U23>0.0070</PDBx:U23>
         <PDBx:U33>0.4729</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2418">
         <PDBx:U11>0.7534</PDBx:U11>
         <PDBx:U12>-0.1013</PDBx:U12>
         <PDBx:U13>0.0821</PDBx:U13>
         <PDBx:U22>0.3419</PDBx:U22>
         <PDBx:U23>0.0085</PDBx:U23>
         <PDBx:U33>0.5044</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2419">
         <PDBx:U11>0.7733</PDBx:U11>
         <PDBx:U12>-0.1194</PDBx:U12>
         <PDBx:U13>0.1008</PDBx:U13>
         <PDBx:U22>0.3642</PDBx:U22>
         <PDBx:U23>-0.0059</PDBx:U23>
         <PDBx:U33>0.5019</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2420">
         <PDBx:U11>0.6887</PDBx:U11>
         <PDBx:U12>-0.1001</PDBx:U12>
         <PDBx:U13>0.0624</PDBx:U13>
         <PDBx:U22>0.2739</PDBx:U22>
         <PDBx:U23>0.0219</PDBx:U23>
         <PDBx:U33>0.4243</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2421">
         <PDBx:U11>0.8029</PDBx:U11>
         <PDBx:U12>-0.1274</PDBx:U12>
         <PDBx:U13>0.0978</PDBx:U13>
         <PDBx:U22>0.3892</PDBx:U22>
         <PDBx:U23>-0.0025</PDBx:U23>
         <PDBx:U33>0.5021</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2422">
         <PDBx:U11>0.7645</PDBx:U11>
         <PDBx:U12>-0.1165</PDBx:U12>
         <PDBx:U13>0.0735</PDBx:U13>
         <PDBx:U22>0.3453</PDBx:U22>
         <PDBx:U23>0.0136</PDBx:U23>
         <PDBx:U33>0.4623</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>377</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>77</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2423">
         <PDBx:U11>0.5509</PDBx:U11>
         <PDBx:U12>-0.0654</PDBx:U12>
         <PDBx:U13>0.0698</PDBx:U13>
         <PDBx:U22>0.2213</PDBx:U22>
         <PDBx:U23>0.0110</PDBx:U23>
         <PDBx:U33>0.4076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2424">
         <PDBx:U11>0.4562</PDBx:U11>
         <PDBx:U12>-0.0612</PDBx:U12>
         <PDBx:U13>0.0520</PDBx:U13>
         <PDBx:U22>0.1673</PDBx:U22>
         <PDBx:U23>0.0177</PDBx:U23>
         <PDBx:U33>0.3335</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2425">
         <PDBx:U11>0.4164</PDBx:U11>
         <PDBx:U12>-0.0631</PDBx:U12>
         <PDBx:U13>0.0637</PDBx:U13>
         <PDBx:U22>0.1776</PDBx:U22>
         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.3142</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2426">
         <PDBx:U11>0.4243</PDBx:U11>
         <PDBx:U12>-0.0718</PDBx:U12>
         <PDBx:U13>0.0573</PDBx:U13>
         <PDBx:U22>0.2117</PDBx:U22>
         <PDBx:U23>-0.0052</PDBx:U23>
         <PDBx:U33>0.3178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2427">
         <PDBx:U11>0.4571</PDBx:U11>
         <PDBx:U12>-0.0390</PDBx:U12>
         <PDBx:U13>0.0308</PDBx:U13>
         <PDBx:U22>0.1734</PDBx:U22>
         <PDBx:U23>0.0405</PDBx:U23>
         <PDBx:U33>0.3767</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2428">
         <PDBx:U11>0.6287</PDBx:U11>
         <PDBx:U12>-0.0360</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.2963</PDBx:U22>
         <PDBx:U23>0.0630</PDBx:U23>
         <PDBx:U33>0.5298</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2429">
         <PDBx:U11>0.6228</PDBx:U11>
         <PDBx:U12>-0.0130</PDBx:U12>
         <PDBx:U13>-0.0180</PDBx:U13>
         <PDBx:U22>0.3052</PDBx:U22>
         <PDBx:U23>0.0852</PDBx:U23>
         <PDBx:U33>0.5858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2430">
         <PDBx:U11>0.6449</PDBx:U11>
         <PDBx:U12>-0.0547</PDBx:U12>
         <PDBx:U13>-0.0107</PDBx:U13>
         <PDBx:U22>0.2898</PDBx:U22>
         <PDBx:U23>0.0663</PDBx:U23>
         <PDBx:U33>0.4899</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>378</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>78</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2431">
         <PDBx:U11>0.4421</PDBx:U11>
         <PDBx:U12>-0.0543</PDBx:U12>
         <PDBx:U13>0.0805</PDBx:U13>
         <PDBx:U22>0.2100</PDBx:U22>
         <PDBx:U23>-0.0107</PDBx:U23>
         <PDBx:U33>0.3568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2432">
         <PDBx:U11>0.4230</PDBx:U11>
         <PDBx:U12>-0.0558</PDBx:U12>
         <PDBx:U13>0.0889</PDBx:U13>
         <PDBx:U22>0.2276</PDBx:U22>
         <PDBx:U23>-0.0271</PDBx:U23>
         <PDBx:U33>0.3467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2433">
         <PDBx:U11>0.4084</PDBx:U11>
         <PDBx:U12>-0.0780</PDBx:U12>
         <PDBx:U13>0.0940</PDBx:U13>
         <PDBx:U22>0.2175</PDBx:U22>
         <PDBx:U23>-0.0476</PDBx:U23>
         <PDBx:U33>0.3076</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2434">
         <PDBx:U11>0.4591</PDBx:U11>
         <PDBx:U12>-0.0829</PDBx:U12>
         <PDBx:U13>0.0896</PDBx:U13>
         <PDBx:U22>0.3027</PDBx:U22>
         <PDBx:U23>-0.0569</PDBx:U23>
         <PDBx:U33>0.3655</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2435">
         <PDBx:U11>0.4295</PDBx:U11>
         <PDBx:U12>-0.0413</PDBx:U12>
         <PDBx:U13>0.1070</PDBx:U13>
         <PDBx:U22>0.2263</PDBx:U22>
         <PDBx:U23>-0.0328</PDBx:U23>
         <PDBx:U33>0.3636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2436">
         <PDBx:U11>0.4178</PDBx:U11>
         <PDBx:U12>-0.0182</PDBx:U12>
         <PDBx:U13>0.1079</PDBx:U13>
         <PDBx:U22>0.2303</PDBx:U22>
         <PDBx:U23>-0.0155</PDBx:U23>
         <PDBx:U33>0.3949</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2437">
         <PDBx:U11>0.5134</PDBx:U11>
         <PDBx:U12>-0.0029</PDBx:U12>
         <PDBx:U13>0.1346</PDBx:U13>
         <PDBx:U22>0.3026</PDBx:U22>
         <PDBx:U23>-0.0207</PDBx:U23>
         <PDBx:U33>0.4949</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2438">
         <PDBx:U11>0.3551</PDBx:U11>
         <PDBx:U12>-0.0175</PDBx:U12>
         <PDBx:U13>0.0999</PDBx:U13>
         <PDBx:U22>0.2119</PDBx:U22>
         <PDBx:U23>-0.0141</PDBx:U23>
         <PDBx:U33>0.3496</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>379</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>79</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2439">
         <PDBx:U11>0.4633</PDBx:U11>
         <PDBx:U12>-0.0915</PDBx:U12>
         <PDBx:U13>0.1031</PDBx:U13>
         <PDBx:U22>0.2372</PDBx:U22>
         <PDBx:U23>-0.0538</PDBx:U23>
         <PDBx:U33>0.3389</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2440">
         <PDBx:U11>0.4645</PDBx:U11>
         <PDBx:U12>-0.1116</PDBx:U12>
         <PDBx:U13>0.1077</PDBx:U13>
         <PDBx:U22>0.2508</PDBx:U22>
         <PDBx:U23>-0.0695</PDBx:U23>
         <PDBx:U33>0.3318</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2441">
         <PDBx:U11>0.4218</PDBx:U11>
         <PDBx:U12>-0.1188</PDBx:U12>
         <PDBx:U13>0.1012</PDBx:U13>
         <PDBx:U22>0.2299</PDBx:U22>
         <PDBx:U23>-0.0650</PDBx:U23>
         <PDBx:U33>0.2897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2442">
         <PDBx:U11>0.4850</PDBx:U11>
         <PDBx:U12>-0.1251</PDBx:U12>
         <PDBx:U13>0.1016</PDBx:U13>
         <PDBx:U22>0.3291</PDBx:U22>
         <PDBx:U23>-0.0750</PDBx:U23>
         <PDBx:U33>0.3675</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2443">
         <PDBx:U11>0.5202</PDBx:U11>
         <PDBx:U12>-0.1192</PDBx:U12>
         <PDBx:U13>0.1173</PDBx:U13>
         <PDBx:U22>0.2764</PDBx:U22>
         <PDBx:U23>-0.0702</PDBx:U23>
         <PDBx:U33>0.3696</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2444">
         <PDBx:U11>0.5648</PDBx:U11>
         <PDBx:U12>-0.1151</PDBx:U12>
         <PDBx:U13>0.1245</PDBx:U13>
         <PDBx:U22>0.3037</PDBx:U22>
         <PDBx:U23>-0.0791</PDBx:U23>
         <PDBx:U33>0.4111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>380</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>80</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2445">
         <PDBx:U11>0.6245</PDBx:U11>
         <PDBx:U12>-0.1251</PDBx:U12>
         <PDBx:U13>0.1327</PDBx:U13>
         <PDBx:U22>0.3345</PDBx:U22>
         <PDBx:U23>-0.0806</PDBx:U23>
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         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
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         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
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         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2567</PDBx:U11>
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         <PDBx:U13>0.0495</PDBx:U13>
         <PDBx:U22>0.2474</PDBx:U22>
         <PDBx:U23>-0.0645</PDBx:U23>
         <PDBx:U33>0.2163</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.4065</PDBx:U11>
         <PDBx:U12>-0.0838</PDBx:U12>
         <PDBx:U13>0.0763</PDBx:U13>
         <PDBx:U22>0.3276</PDBx:U22>
         <PDBx:U23>-0.0792</PDBx:U23>
         <PDBx:U33>0.3327</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2464">
         <PDBx:U11>0.4157</PDBx:U11>
         <PDBx:U12>-0.0997</PDBx:U12>
         <PDBx:U13>0.0741</PDBx:U13>
         <PDBx:U22>0.3463</PDBx:U22>
         <PDBx:U23>-0.0916</PDBx:U23>
         <PDBx:U33>0.3436</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2465">
         <PDBx:U11>0.4491</PDBx:U11>
         <PDBx:U12>-0.1103</PDBx:U12>
         <PDBx:U13>0.0818</PDBx:U13>
         <PDBx:U22>0.3643</PDBx:U22>
         <PDBx:U23>-0.0916</PDBx:U23>
         <PDBx:U33>0.3727</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2466">
         <PDBx:U11>0.4217</PDBx:U11>
         <PDBx:U12>-0.1002</PDBx:U12>
         <PDBx:U13>0.0624</PDBx:U13>
         <PDBx:U22>0.3842</PDBx:U22>
         <PDBx:U23>-0.0976</PDBx:U23>
         <PDBx:U33>0.3654</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2467">
         <PDBx:U11>0.4117</PDBx:U11>
         <PDBx:U12>-0.1177</PDBx:U12>
         <PDBx:U13>0.0788</PDBx:U13>
         <PDBx:U22>0.3507</PDBx:U22>
         <PDBx:U23>-0.0994</PDBx:U23>
         <PDBx:U33>0.3522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2468">
         <PDBx:U11>0.4116</PDBx:U11>
         <PDBx:U12>-0.1111</PDBx:U12>
         <PDBx:U13>0.0651</PDBx:U13>
         <PDBx:U22>0.3787</PDBx:U22>
         <PDBx:U23>-0.1030</PDBx:U23>
         <PDBx:U33>0.3662</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2469">
         <PDBx:U11>0.3822</PDBx:U11>
         <PDBx:U12>-0.0919</PDBx:U12>
         <PDBx:U13>0.0500</PDBx:U13>
         <PDBx:U22>0.3648</PDBx:U22>
         <PDBx:U23>-0.0986</PDBx:U23>
         <PDBx:U33>0.3304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2470">
         <PDBx:U11>0.4296</PDBx:U11>
         <PDBx:U12>-0.1133</PDBx:U12>
         <PDBx:U13>0.0543</PDBx:U13>
         <PDBx:U22>0.4217</PDBx:U22>
         <PDBx:U23>-0.1106</PDBx:U23>
         <PDBx:U33>0.4059</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2471">
         <PDBx:U11>0.3895</PDBx:U11>
         <PDBx:U12>-0.0937</PDBx:U12>
         <PDBx:U13>0.0369</PDBx:U13>
         <PDBx:U22>0.3925</PDBx:U22>
         <PDBx:U23>-0.1042</PDBx:U23>
         <PDBx:U33>0.3529</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2472">
         <PDBx:U11>0.4251</PDBx:U11>
         <PDBx:U12>-0.1040</PDBx:U12>
         <PDBx:U13>0.0384</PDBx:U13>
         <PDBx:U22>0.4335</PDBx:U22>
         <PDBx:U23>-0.1106</PDBx:U23>
         <PDBx:U33>0.4055</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>383</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>83</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2473">
         <PDBx:U11>0.3016</PDBx:U11>
         <PDBx:U12>-0.0945</PDBx:U12>
         <PDBx:U13>0.0547</PDBx:U13>
         <PDBx:U22>0.2824</PDBx:U22>
         <PDBx:U23>-0.0788</PDBx:U23>
         <PDBx:U33>0.2531</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2474">
         <PDBx:U11>0.2659</PDBx:U11>
         <PDBx:U12>-0.0900</PDBx:U12>
         <PDBx:U13>0.0453</PDBx:U13>
         <PDBx:U22>0.2799</PDBx:U22>
         <PDBx:U23>-0.0793</PDBx:U23>
         <PDBx:U33>0.2352</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2475">
         <PDBx:U11>0.2650</PDBx:U11>
         <PDBx:U12>-0.0864</PDBx:U12>
         <PDBx:U13>0.0368</PDBx:U13>
         <PDBx:U22>0.2845</PDBx:U22>
         <PDBx:U23>-0.0699</PDBx:U23>
         <PDBx:U33>0.2338</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2476">
         <PDBx:U11>0.2671</PDBx:U11>
         <PDBx:U12>-0.0782</PDBx:U12>
         <PDBx:U13>0.0272</PDBx:U13>
         <PDBx:U22>0.3078</PDBx:U22>
         <PDBx:U23>-0.0677</PDBx:U23>
         <PDBx:U33>0.2472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2477">
         <PDBx:U11>0.2480</PDBx:U11>
         <PDBx:U12>-0.0966</PDBx:U12>
         <PDBx:U13>0.0517</PDBx:U13>
         <PDBx:U22>0.2714</PDBx:U22>
         <PDBx:U23>-0.0863</PDBx:U23>
         <PDBx:U33>0.2290</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2478">
         <PDBx:U11>0.2927</PDBx:U11>
         <PDBx:U12>-0.0906</PDBx:U12>
         <PDBx:U13>0.0439</PDBx:U13>
         <PDBx:U22>0.3445</PDBx:U22>
         <PDBx:U23>-0.0899</PDBx:U23>
         <PDBx:U33>0.2959</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2479">
         <PDBx:U11>0.3357</PDBx:U11>
         <PDBx:U12>-0.0811</PDBx:U12>
         <PDBx:U13>0.0285</PDBx:U13>
         <PDBx:U22>0.3989</PDBx:U22>
         <PDBx:U23>-0.0898</PDBx:U23>
         <PDBx:U33>0.3440</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2480">
         <PDBx:U11>0.2398</PDBx:U11>
         <PDBx:U12>-0.0985</PDBx:U12>
         <PDBx:U13>0.0529</PDBx:U13>
         <PDBx:U22>0.2995</PDBx:U22>
         <PDBx:U23>-0.1014</PDBx:U23>
         <PDBx:U33>0.2619</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>384</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>84</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2481">
         <PDBx:U11>0.2420</PDBx:U11>
         <PDBx:U12>-0.0903</PDBx:U12>
         <PDBx:U13>0.0379</PDBx:U13>
         <PDBx:U22>0.2368</PDBx:U22>
         <PDBx:U23>-0.0602</PDBx:U23>
         <PDBx:U33>0.1945</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2482">
         <PDBx:U11>0.2763</PDBx:U11>
         <PDBx:U12>-0.0850</PDBx:U12>
         <PDBx:U13>0.0243</PDBx:U13>
         <PDBx:U22>0.2689</PDBx:U22>
         <PDBx:U23>-0.0463</PDBx:U23>
         <PDBx:U33>0.2247</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2483">
         <PDBx:U11>0.2703</PDBx:U11>
         <PDBx:U12>-0.0712</PDBx:U12>
         <PDBx:U13>0.0139</PDBx:U13>
         <PDBx:U22>0.2790</PDBx:U22>
         <PDBx:U23>-0.0344</PDBx:U23>
         <PDBx:U33>0.2401</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2484">
         <PDBx:U11>0.2280</PDBx:U11>
         <PDBx:U12>-0.0670</PDBx:U12>
         <PDBx:U13>0.0024</PDBx:U13>
         <PDBx:U22>0.2513</PDBx:U22>
         <PDBx:U23>-0.0287</PDBx:U23>
         <PDBx:U33>0.2071</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2485">
         <PDBx:U11>0.2684</PDBx:U11>
         <PDBx:U12>-0.0892</PDBx:U12>
         <PDBx:U13>0.0211</PDBx:U13>
         <PDBx:U22>0.2219</PDBx:U22>
         <PDBx:U23>-0.0338</PDBx:U23>
         <PDBx:U33>0.1891</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2486">
         <PDBx:U11>0.2956</PDBx:U11>
         <PDBx:U12>-0.1038</PDBx:U12>
         <PDBx:U13>0.0344</PDBx:U13>
         <PDBx:U22>0.2232</PDBx:U22>
         <PDBx:U23>-0.0422</PDBx:U23>
         <PDBx:U33>0.1839</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2487">
         <PDBx:U11>0.3973</PDBx:U11>
         <PDBx:U12>-0.1078</PDBx:U12>
         <PDBx:U13>0.0266</PDBx:U13>
         <PDBx:U22>0.2749</PDBx:U22>
         <PDBx:U23>-0.0274</PDBx:U23>
         <PDBx:U33>0.2431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2488">
         <PDBx:U11>0.4292</PDBx:U11>
         <PDBx:U12>-0.1121</PDBx:U12>
         <PDBx:U13>0.0344</PDBx:U13>
         <PDBx:U22>0.2781</PDBx:U22>
         <PDBx:U23>-0.0244</PDBx:U23>
         <PDBx:U33>0.2587</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2489">
         <PDBx:U11>0.4683</PDBx:U11>
         <PDBx:U12>-0.1070</PDBx:U12>
         <PDBx:U13>0.0100</PDBx:U13>
         <PDBx:U22>0.3302</PDBx:U22>
         <PDBx:U23>-0.0183</PDBx:U23>
         <PDBx:U33>0.2929</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>385</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>85</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2490">
         <PDBx:U11>0.2244</PDBx:U11>
         <PDBx:U12>-0.0646</PDBx:U12>
         <PDBx:U13>0.0213</PDBx:U13>
         <PDBx:U22>0.2272</PDBx:U22>
         <PDBx:U23>-0.0308</PDBx:U23>
         <PDBx:U33>0.2023</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2491">
         <PDBx:U11>0.2084</PDBx:U11>
         <PDBx:U12>-0.0514</PDBx:U12>
         <PDBx:U13>0.0202</PDBx:U13>
         <PDBx:U22>0.2226</PDBx:U22>
         <PDBx:U23>-0.0189</PDBx:U23>
         <PDBx:U33>0.2104</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2492">
         <PDBx:U11>0.2130</PDBx:U11>
         <PDBx:U12>-0.0481</PDBx:U12>
         <PDBx:U13>0.0231</PDBx:U13>
         <PDBx:U22>0.2486</PDBx:U22>
         <PDBx:U23>-0.0273</PDBx:U23>
         <PDBx:U33>0.2172</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2493">
         <PDBx:U11>0.1832</PDBx:U11>
         <PDBx:U12>-0.0415</PDBx:U12>
         <PDBx:U13>0.0179</PDBx:U13>
         <PDBx:U22>0.2328</PDBx:U22>
         <PDBx:U23>-0.0172</PDBx:U23>
         <PDBx:U33>0.2036</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2494">
         <PDBx:U11>0.2150</PDBx:U11>
         <PDBx:U12>-0.0436</PDBx:U12>
         <PDBx:U13>0.0335</PDBx:U13>
         <PDBx:U22>0.2112</PDBx:U22>
         <PDBx:U23>-0.0142</PDBx:U23>
         <PDBx:U33>0.2241</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2495">
         <PDBx:U11>0.3126</PDBx:U11>
         <PDBx:U12>-0.0440</PDBx:U12>
         <PDBx:U13>0.0240</PDBx:U13>
         <PDBx:U22>0.2850</PDBx:U22>
         <PDBx:U23>-0.0006</PDBx:U23>
         <PDBx:U33>0.3230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2496">
         <PDBx:U11>0.2140</PDBx:U11>
         <PDBx:U12>-0.0297</PDBx:U12>
         <PDBx:U13>0.0424</PDBx:U13>
         <PDBx:U22>0.2221</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.2507</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2497">
         <PDBx:U11>0.3818</PDBx:U11>
         <PDBx:U12>-0.0357</PDBx:U12>
         <PDBx:U13>0.0368</PDBx:U13>
         <PDBx:U22>0.3316</PDBx:U22>
         <PDBx:U23>0.0035</PDBx:U23>
         <PDBx:U33>0.3997</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>386</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>86</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2498">
         <PDBx:U11>0.2547</PDBx:U11>
         <PDBx:U12>-0.0539</PDBx:U12>
         <PDBx:U13>0.0290</PDBx:U13>
         <PDBx:U22>0.2900</PDBx:U22>
         <PDBx:U23>-0.0449</PDBx:U23>
         <PDBx:U33>0.2422</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2499">
         <PDBx:U11>0.2477</PDBx:U11>
         <PDBx:U12>-0.0520</PDBx:U12>
         <PDBx:U13>0.0249</PDBx:U13>
         <PDBx:U22>0.2969</PDBx:U22>
         <PDBx:U23>-0.0531</PDBx:U23>
         <PDBx:U33>0.2295</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2500">
         <PDBx:U11>0.2330</PDBx:U11>
         <PDBx:U12>-0.0529</PDBx:U12>
         <PDBx:U13>0.0105</PDBx:U13>
         <PDBx:U22>0.3021</PDBx:U22>
         <PDBx:U23>-0.0506</PDBx:U23>
         <PDBx:U33>0.2252</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2501">
         <PDBx:U11>0.2493</PDBx:U11>
         <PDBx:U12>-0.0466</PDBx:U12>
         <PDBx:U13>0.0050</PDBx:U13>
         <PDBx:U22>0.3275</PDBx:U22>
         <PDBx:U23>-0.0456</PDBx:U23>
         <PDBx:U33>0.2433</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2502">
         <PDBx:U11>0.2420</PDBx:U11>
         <PDBx:U12>-0.0608</PDBx:U12>
         <PDBx:U13>0.0249</PDBx:U13>
         <PDBx:U22>0.2863</PDBx:U22>
         <PDBx:U23>-0.0727</PDBx:U23>
         <PDBx:U33>0.2084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2503">
         <PDBx:U11>0.3347</PDBx:U11>
         <PDBx:U12>-0.0607</PDBx:U12>
         <PDBx:U13>0.0375</PDBx:U13>
         <PDBx:U22>0.3522</PDBx:U22>
         <PDBx:U23>-0.0794</PDBx:U23>
         <PDBx:U33>0.2796</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2504">
         <PDBx:U11>0.3136</PDBx:U11>
         <PDBx:U12>-0.0676</PDBx:U12>
         <PDBx:U13>0.0277</PDBx:U13>
         <PDBx:U22>0.3287</PDBx:U22>
         <PDBx:U23>-0.0904</PDBx:U23>
         <PDBx:U33>0.2545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2505">
         <PDBx:U11>0.3257</PDBx:U11>
         <PDBx:U12>-0.0483</PDBx:U12>
         <PDBx:U13>0.0473</PDBx:U13>
         <PDBx:U22>0.3303</PDBx:U22>
         <PDBx:U23>-0.0721</PDBx:U23>
         <PDBx:U33>0.2549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>387</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>87</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2506">
         <PDBx:U11>0.2054</PDBx:U11>
         <PDBx:U12>-0.0608</PDBx:U12>
         <PDBx:U13>0.0070</PDBx:U13>
         <PDBx:U22>0.2753</PDBx:U22>
         <PDBx:U23>-0.0543</PDBx:U23>
         <PDBx:U33>0.1998</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2507">
         <PDBx:U11>0.2045</PDBx:U11>
         <PDBx:U12>-0.0559</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.2805</PDBx:U22>
         <PDBx:U23>-0.0499</PDBx:U23>
         <PDBx:U33>0.2043</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2508">
         <PDBx:U11>0.2378</PDBx:U11>
         <PDBx:U12>-0.0531</PDBx:U12>
         <PDBx:U13>-0.0119</PDBx:U13>
         <PDBx:U22>0.3151</PDBx:U22>
         <PDBx:U23>-0.0362</PDBx:U23>
         <PDBx:U33>0.2421</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2509">
         <PDBx:U11>0.2298</PDBx:U11>
         <PDBx:U12>-0.0456</PDBx:U12>
         <PDBx:U13>-0.0184</PDBx:U13>
         <PDBx:U22>0.3111</PDBx:U22>
         <PDBx:U23>-0.0319</PDBx:U23>
         <PDBx:U33>0.2384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2510">
         <PDBx:U11>0.2529</PDBx:U11>
         <PDBx:U12>-0.0619</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.3195</PDBx:U22>
         <PDBx:U23>-0.0546</PDBx:U23>
         <PDBx:U33>0.2479</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2511">
         <PDBx:U11>0.2148</PDBx:U11>
         <PDBx:U12>-0.0639</PDBx:U12>
         <PDBx:U13>0.0139</PDBx:U13>
         <PDBx:U22>0.2901</PDBx:U22>
         <PDBx:U23>-0.0668</PDBx:U23>
         <PDBx:U33>0.2205</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2512">
         <PDBx:U11>0.2672</PDBx:U11>
         <PDBx:U12>-0.0758</PDBx:U12>
         <PDBx:U13>0.0298</PDBx:U13>
         <PDBx:U22>0.3362</PDBx:U22>
         <PDBx:U23>-0.0762</PDBx:U23>
         <PDBx:U33>0.2715</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2513">
         <PDBx:U11>0.2068</PDBx:U11>
         <PDBx:U12>-0.0762</PDBx:U12>
         <PDBx:U13>0.0338</PDBx:U13>
         <PDBx:U22>0.2959</PDBx:U22>
         <PDBx:U23>-0.0911</PDBx:U23>
         <PDBx:U33>0.2406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>388</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>88</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2514">
         <PDBx:U11>0.1963</PDBx:U11>
         <PDBx:U12>-0.0558</PDBx:U12>
         <PDBx:U13>-0.0144</PDBx:U13>
         <PDBx:U22>0.2624</PDBx:U22>
         <PDBx:U23>-0.0248</PDBx:U23>
         <PDBx:U33>0.2021</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2515">
         <PDBx:U11>0.2029</PDBx:U11>
         <PDBx:U12>-0.0525</PDBx:U12>
         <PDBx:U13>-0.0285</PDBx:U13>
         <PDBx:U22>0.2687</PDBx:U22>
         <PDBx:U23>-0.0079</PDBx:U23>
         <PDBx:U33>0.2219</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2516">
         <PDBx:U11>0.1657</PDBx:U11>
         <PDBx:U12>-0.0439</PDBx:U12>
         <PDBx:U13>-0.0244</PDBx:U13>
         <PDBx:U22>0.2477</PDBx:U22>
         <PDBx:U23>0.0002</PDBx:U23>
         <PDBx:U33>0.2070</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2517">
         <PDBx:U11>0.1790</PDBx:U11>
         <PDBx:U12>-0.0425</PDBx:U12>
         <PDBx:U13>-0.0344</PDBx:U13>
         <PDBx:U22>0.2678</PDBx:U22>
         <PDBx:U23>0.0099</PDBx:U23>
         <PDBx:U33>0.2336</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2518">
         <PDBx:U11>0.2029</PDBx:U11>
         <PDBx:U12>-0.0541</PDBx:U12>
         <PDBx:U13>-0.0371</PDBx:U13>
         <PDBx:U22>0.2487</PDBx:U22>
         <PDBx:U23>0.0062</PDBx:U23>
         <PDBx:U33>0.2249</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2519">
         <PDBx:U11>0.1743</PDBx:U11>
         <PDBx:U12>-0.0544</PDBx:U12>
         <PDBx:U13>-0.0595</PDBx:U13>
         <PDBx:U22>0.2185</PDBx:U22>
         <PDBx:U23>0.0224</PDBx:U23>
         <PDBx:U33>0.2121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2520">
         <PDBx:U11>0.1543</PDBx:U11>
         <PDBx:U12>-0.0467</PDBx:U12>
         <PDBx:U13>-0.0246</PDBx:U13>
         <PDBx:U22>0.2011</PDBx:U22>
         <PDBx:U23>0.0121</PDBx:U23>
         <PDBx:U33>0.1966</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2521">
         <PDBx:U11>0.2200</PDBx:U11>
         <PDBx:U12>-0.0571</PDBx:U12>
         <PDBx:U13>-0.0784</PDBx:U13>
         <PDBx:U22>0.2400</PDBx:U22>
         <PDBx:U23>0.0371</PDBx:U23>
         <PDBx:U33>0.2585</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>389</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>89</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2522">
         <PDBx:U11>0.1970</PDBx:U11>
         <PDBx:U12>-0.0392</PDBx:U12>
         <PDBx:U13>-0.0078</PDBx:U13>
         <PDBx:U22>0.2793</PDBx:U22>
         <PDBx:U23>-0.0043</PDBx:U23>
         <PDBx:U33>0.2370</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2523">
         <PDBx:U11>0.1795</PDBx:U11>
         <PDBx:U12>-0.0316</PDBx:U12>
         <PDBx:U13>0.0031</PDBx:U13>
         <PDBx:U22>0.2672</PDBx:U22>
         <PDBx:U23>0.0013</PDBx:U23>
         <PDBx:U33>0.2266</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2524">
         <PDBx:U11>0.2021</PDBx:U11>
         <PDBx:U12>-0.0319</PDBx:U12>
         <PDBx:U13>-0.0042</PDBx:U13>
         <PDBx:U22>0.2963</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.2324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2525">
         <PDBx:U11>0.2098</PDBx:U11>
         <PDBx:U12>-0.0286</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.3074</PDBx:U22>
         <PDBx:U23>0.0048</PDBx:U23>
         <PDBx:U33>0.2480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>390</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>90</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2526">
         <PDBx:U11>0.1852</PDBx:U11>
         <PDBx:U12>-0.0361</PDBx:U12>
         <PDBx:U13>-0.0102</PDBx:U13>
         <PDBx:U22>0.2805</PDBx:U22>
         <PDBx:U23>-0.0224</PDBx:U23>
         <PDBx:U33>0.1967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2527">
         <PDBx:U11>0.2068</PDBx:U11>
         <PDBx:U12>-0.0350</PDBx:U12>
         <PDBx:U13>-0.0218</PDBx:U13>
         <PDBx:U22>0.3084</PDBx:U22>
         <PDBx:U23>-0.0294</PDBx:U23>
         <PDBx:U33>0.2082</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2528">
         <PDBx:U11>0.2588</PDBx:U11>
         <PDBx:U12>-0.0321</PDBx:U12>
         <PDBx:U13>-0.0315</PDBx:U13>
         <PDBx:U22>0.3582</PDBx:U22>
         <PDBx:U23>-0.0195</PDBx:U23>
         <PDBx:U33>0.2718</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2529">
         <PDBx:U11>0.2798</PDBx:U11>
         <PDBx:U12>-0.0289</PDBx:U12>
         <PDBx:U13>-0.0373</PDBx:U13>
         <PDBx:U22>0.3805</PDBx:U22>
         <PDBx:U23>-0.0138</PDBx:U23>
         <PDBx:U33>0.2903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2530">
         <PDBx:U11>0.2637</PDBx:U11>
         <PDBx:U12>-0.0347</PDBx:U12>
         <PDBx:U13>-0.0231</PDBx:U13>
         <PDBx:U22>0.3577</PDBx:U22>
         <PDBx:U23>-0.0418</PDBx:U23>
         <PDBx:U33>0.2618</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2531">
         <PDBx:U11>0.2327</PDBx:U11>
         <PDBx:U12>-0.0284</PDBx:U12>
         <PDBx:U13>-0.0336</PDBx:U13>
         <PDBx:U22>0.3204</PDBx:U22>
         <PDBx:U23>-0.0421</PDBx:U23>
         <PDBx:U33>0.2323</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2532">
         <PDBx:U11>0.2202</PDBx:U11>
         <PDBx:U12>-0.0255</PDBx:U12>
         <PDBx:U13>-0.0415</PDBx:U13>
         <PDBx:U22>0.3022</PDBx:U22>
         <PDBx:U23>-0.0421</PDBx:U23>
         <PDBx:U33>0.1989</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2533">
         <PDBx:U11>0.2069</PDBx:U11>
         <PDBx:U12>-0.0303</PDBx:U12>
         <PDBx:U13>-0.0336</PDBx:U13>
         <PDBx:U22>0.2959</PDBx:U22>
         <PDBx:U23>-0.0511</PDBx:U23>
         <PDBx:U33>0.2171</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>391</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>91</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2534">
         <PDBx:U11>0.2313</PDBx:U11>
         <PDBx:U12>-0.0332</PDBx:U12>
         <PDBx:U13>-0.0327</PDBx:U13>
         <PDBx:U22>0.3191</PDBx:U22>
         <PDBx:U23>-0.0180</PDBx:U23>
         <PDBx:U33>0.2494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2535">
         <PDBx:U11>0.2414</PDBx:U11>
         <PDBx:U12>-0.0302</PDBx:U12>
         <PDBx:U13>-0.0412</PDBx:U13>
         <PDBx:U22>0.3163</PDBx:U22>
         <PDBx:U23>-0.0130</PDBx:U23>
         <PDBx:U33>0.2622</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2536">
         <PDBx:U11>0.3288</PDBx:U11>
         <PDBx:U12>-0.0307</PDBx:U12>
         <PDBx:U13>-0.0457</PDBx:U13>
         <PDBx:U22>0.4093</PDBx:U22>
         <PDBx:U23>0.0005</PDBx:U23>
         <PDBx:U33>0.3628</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2537">
         <PDBx:U11>0.3417</PDBx:U11>
         <PDBx:U12>-0.0281</PDBx:U12>
         <PDBx:U13>-0.0508</PDBx:U13>
         <PDBx:U22>0.4167</PDBx:U22>
         <PDBx:U23>0.0030</PDBx:U23>
         <PDBx:U33>0.3753</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2538">
         <PDBx:U11>0.3010</PDBx:U11>
         <PDBx:U12>-0.0343</PDBx:U12>
         <PDBx:U13>-0.0422</PDBx:U13>
         <PDBx:U22>0.3635</PDBx:U22>
         <PDBx:U23>-0.0158</PDBx:U23>
         <PDBx:U33>0.3146</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2539">
         <PDBx:U11>0.4133</PDBx:U11>
         <PDBx:U12>-0.0333</PDBx:U12>
         <PDBx:U13>-0.0504</PDBx:U13>
         <PDBx:U22>0.4660</PDBx:U22>
         <PDBx:U23>-0.0121</PDBx:U23>
         <PDBx:U33>0.4240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2540">
         <PDBx:U11>0.2679</PDBx:U11>
         <PDBx:U12>-0.0364</PDBx:U12>
         <PDBx:U13>-0.0348</PDBx:U13>
         <PDBx:U22>0.3297</PDBx:U22>
         <PDBx:U23>-0.0274</PDBx:U23>
         <PDBx:U33>0.2733</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>392</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>92</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2541">
         <PDBx:U11>0.2184</PDBx:U11>
         <PDBx:U12>-0.0350</PDBx:U12>
         <PDBx:U13>-0.0425</PDBx:U13>
         <PDBx:U22>0.3109</PDBx:U22>
         <PDBx:U23>0.0119</PDBx:U23>
         <PDBx:U33>0.2697</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2542">
         <PDBx:U11>0.2114</PDBx:U11>
         <PDBx:U12>-0.0352</PDBx:U12>
         <PDBx:U13>-0.0438</PDBx:U13>
         <PDBx:U22>0.3090</PDBx:U22>
         <PDBx:U23>0.0303</PDBx:U23>
         <PDBx:U33>0.2909</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2543">
         <PDBx:U11>0.2676</PDBx:U11>
         <PDBx:U12>-0.0340</PDBx:U12>
         <PDBx:U13>-0.0378</PDBx:U13>
         <PDBx:U22>0.3767</PDBx:U22>
         <PDBx:U23>0.0375</PDBx:U23>
         <PDBx:U33>0.3522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2544">
         <PDBx:U11>0.2913</PDBx:U11>
         <PDBx:U12>-0.0358</PDBx:U12>
         <PDBx:U13>-0.0440</PDBx:U13>
         <PDBx:U22>0.3980</PDBx:U22>
         <PDBx:U23>0.0483</PDBx:U23>
         <PDBx:U33>0.3889</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2545">
         <PDBx:U11>0.1786</PDBx:U11>
         <PDBx:U12>-0.0349</PDBx:U12>
         <PDBx:U13>-0.0363</PDBx:U13>
         <PDBx:U22>0.2846</PDBx:U22>
         <PDBx:U23>0.0419</PDBx:U23>
         <PDBx:U33>0.2904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2546">
         <PDBx:U11>0.2079</PDBx:U11>
         <PDBx:U12>-0.0314</PDBx:U12>
         <PDBx:U13>-0.0273</PDBx:U13>
         <PDBx:U22>0.3201</PDBx:U22>
         <PDBx:U23>0.0593</PDBx:U23>
         <PDBx:U33>0.3591</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2547">
         <PDBx:U11>0.2045</PDBx:U11>
         <PDBx:U12>-0.0256</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.3262</PDBx:U22>
         <PDBx:U23>0.0666</PDBx:U23>
         <PDBx:U33>0.3781</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2548">
         <PDBx:U11>0.2142</PDBx:U11>
         <PDBx:U12>-0.0327</PDBx:U12>
         <PDBx:U13>-0.0398</PDBx:U13>
         <PDBx:U22>0.3161</PDBx:U22>
         <PDBx:U23>0.0699</PDBx:U23>
         <PDBx:U33>0.3813</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2549">
         <PDBx:U11>0.2386</PDBx:U11>
         <PDBx:U12>-0.0231</PDBx:U12>
         <PDBx:U13>0.0048</PDBx:U13>
         <PDBx:U22>0.3596</PDBx:U22>
         <PDBx:U23>0.0806</PDBx:U23>
         <PDBx:U33>0.4468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2550">
         <PDBx:U11>0.2347</PDBx:U11>
         <PDBx:U12>-0.0284</PDBx:U12>
         <PDBx:U13>-0.0224</PDBx:U13>
         <PDBx:U22>0.3469</PDBx:U22>
         <PDBx:U23>0.0838</PDBx:U23>
         <PDBx:U33>0.4432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2551">
         <PDBx:U11>0.2630</PDBx:U11>
         <PDBx:U12>-0.0374</PDBx:U12>
         <PDBx:U13>-0.0600</PDBx:U13>
         <PDBx:U22>0.3448</PDBx:U22>
         <PDBx:U23>0.0686</PDBx:U23>
         <PDBx:U33>0.4120</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2552">
         <PDBx:U11>0.2891</PDBx:U11>
         <PDBx:U12>-0.0299</PDBx:U12>
         <PDBx:U13>-0.0300</PDBx:U13>
         <PDBx:U22>0.3972</PDBx:U22>
         <PDBx:U23>0.0970</PDBx:U23>
         <PDBx:U33>0.5280</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2553">
         <PDBx:U11>0.2525</PDBx:U11>
         <PDBx:U12>-0.0400</PDBx:U12>
         <PDBx:U13>-0.0686</PDBx:U13>
         <PDBx:U22>0.3285</PDBx:U22>
         <PDBx:U23>0.0824</PDBx:U23>
         <PDBx:U33>0.4279</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ3</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ3</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2554">
         <PDBx:U11>0.2949</PDBx:U11>
         <PDBx:U12>-0.0367</PDBx:U12>
         <PDBx:U13>-0.0559</PDBx:U13>
         <PDBx:U22>0.3862</PDBx:U22>
         <PDBx:U23>0.0968</PDBx:U23>
         <PDBx:U33>0.5179</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TRP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>393</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TRP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>93</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2555">
         <PDBx:U11>0.2438</PDBx:U11>
         <PDBx:U12>-0.0287</PDBx:U12>
         <PDBx:U13>-0.0224</PDBx:U13>
         <PDBx:U22>0.3488</PDBx:U22>
         <PDBx:U23>0.0286</PDBx:U23>
         <PDBx:U33>0.3035</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2556">
         <PDBx:U11>0.2624</PDBx:U11>
         <PDBx:U12>-0.0248</PDBx:U12>
         <PDBx:U13>-0.0123</PDBx:U13>
         <PDBx:U22>0.3579</PDBx:U22>
         <PDBx:U23>0.0330</PDBx:U23>
         <PDBx:U33>0.3039</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2557">
         <PDBx:U11>0.2596</PDBx:U11>
         <PDBx:U12>-0.0243</PDBx:U12>
         <PDBx:U13>-0.0308</PDBx:U13>
         <PDBx:U22>0.3504</PDBx:U22>
         <PDBx:U23>0.0260</PDBx:U23>
         <PDBx:U33>0.2769</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2558">
         <PDBx:U11>0.3778</PDBx:U11>
         <PDBx:U12>-0.0214</PDBx:U12>
         <PDBx:U13>-0.0280</PDBx:U13>
         <PDBx:U22>0.4547</PDBx:U22>
         <PDBx:U23>0.0311</PDBx:U23>
         <PDBx:U33>0.3737</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2559">
         <PDBx:U11>0.3142</PDBx:U11>
         <PDBx:U12>-0.0198</PDBx:U12>
         <PDBx:U13>0.0092</PDBx:U13>
         <PDBx:U22>0.3952</PDBx:U22>
         <PDBx:U23>0.0267</PDBx:U23>
         <PDBx:U33>0.3267</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2560">
         <PDBx:U11>0.3195</PDBx:U11>
         <PDBx:U12>-0.0203</PDBx:U12>
         <PDBx:U13>0.0003</PDBx:U13>
         <PDBx:U22>0.3968</PDBx:U22>
         <PDBx:U23>0.0065</PDBx:U23>
         <PDBx:U33>0.3021</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2561">
         <PDBx:U11>0.3611</PDBx:U11>
         <PDBx:U12>-0.0170</PDBx:U12>
         <PDBx:U13>0.0198</PDBx:U13>
         <PDBx:U22>0.4148</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.3081</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2562">
         <PDBx:U11>0.3952</PDBx:U11>
         <PDBx:U12>-0.0201</PDBx:U12>
         <PDBx:U13>0.0082</PDBx:U13>
         <PDBx:U22>0.4441</PDBx:U22>
         <PDBx:U23>-0.0185</PDBx:U23>
         <PDBx:U33>0.3177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2563">
         <PDBx:U11>0.3443</PDBx:U11>
         <PDBx:U12>-0.0233</PDBx:U12>
         <PDBx:U13>0.0131</PDBx:U13>
         <PDBx:U22>0.3966</PDBx:U22>
         <PDBx:U23>-0.0271</PDBx:U23>
         <PDBx:U33>0.2767</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2564">
         <PDBx:U11>0.3081</PDBx:U11>
         <PDBx:U12>-0.0220</PDBx:U12>
         <PDBx:U13>0.0271</PDBx:U13>
         <PDBx:U22>0.3667</PDBx:U22>
         <PDBx:U23>-0.0176</PDBx:U23>
         <PDBx:U33>0.2713</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2565">
         <PDBx:U11>0.3089</PDBx:U11>
         <PDBx:U12>-0.0284</PDBx:U12>
         <PDBx:U13>0.0020</PDBx:U13>
         <PDBx:U22>0.3570</PDBx:U22>
         <PDBx:U23>-0.0443</PDBx:U23>
         <PDBx:U33>0.2236</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>394</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>94</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2566">
         <PDBx:U11>0.2828</PDBx:U11>
         <PDBx:U12>-0.0258</PDBx:U12>
         <PDBx:U13>-0.0474</PDBx:U13>
         <PDBx:U22>0.2503</PDBx:U22>
         <PDBx:U23>-0.0097</PDBx:U23>
         <PDBx:U33>0.2769</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2567">
         <PDBx:U11>0.3534</PDBx:U11>
         <PDBx:U12>0.0047</PDBx:U12>
         <PDBx:U13>-0.0438</PDBx:U13>
         <PDBx:U22>0.2736</PDBx:U22>
         <PDBx:U23>0.0080</PDBx:U23>
         <PDBx:U33>0.3002</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2568">
         <PDBx:U11>0.4679</PDBx:U11>
         <PDBx:U12>0.0031</PDBx:U12>
         <PDBx:U13>-0.0419</PDBx:U13>
         <PDBx:U22>0.3140</PDBx:U22>
         <PDBx:U23>-0.0014</PDBx:U23>
         <PDBx:U33>0.3839</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2569">
         <PDBx:U11>0.5476</PDBx:U11>
         <PDBx:U12>0.0273</PDBx:U12>
         <PDBx:U13>-0.0375</PDBx:U13>
         <PDBx:U22>0.3434</PDBx:U22>
         <PDBx:U23>0.0097</PDBx:U23>
         <PDBx:U33>0.4270</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2570">
         <PDBx:U11>0.3247</PDBx:U11>
         <PDBx:U12>0.0408</PDBx:U12>
         <PDBx:U13>-0.0485</PDBx:U13>
         <PDBx:U22>0.2805</PDBx:U22>
         <PDBx:U23>0.0141</PDBx:U23>
         <PDBx:U33>0.2779</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2571">
         <PDBx:U11>0.2930</PDBx:U11>
         <PDBx:U12>0.0418</PDBx:U12>
         <PDBx:U13>-0.0493</PDBx:U13>
         <PDBx:U22>0.3183</PDBx:U22>
         <PDBx:U23>0.0199</PDBx:U23>
         <PDBx:U33>0.2775</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>395</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>95</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2572">
         <PDBx:U11>0.4356</PDBx:U11>
         <PDBx:U12>-0.0249</PDBx:U12>
         <PDBx:U13>-0.0462</PDBx:U13>
         <PDBx:U22>0.2767</PDBx:U22>
         <PDBx:U23>-0.0241</PDBx:U23>
         <PDBx:U33>0.3710</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2573">
         <PDBx:U11>0.5576</PDBx:U11>
         <PDBx:U12>-0.0300</PDBx:U12>
         <PDBx:U13>-0.0464</PDBx:U13>
         <PDBx:U22>0.3365</PDBx:U22>
         <PDBx:U23>-0.0399</PDBx:U23>
         <PDBx:U33>0.4695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2574">
         <PDBx:U11>0.6468</PDBx:U11>
         <PDBx:U12>-0.0320</PDBx:U12>
         <PDBx:U13>-0.0308</PDBx:U13>
         <PDBx:U22>0.3502</PDBx:U22>
         <PDBx:U23>-0.0301</PDBx:U23>
         <PDBx:U33>0.5183</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2575">
         <PDBx:U11>0.6922</PDBx:U11>
         <PDBx:U12>-0.0150</PDBx:U12>
         <PDBx:U13>-0.0275</PDBx:U13>
         <PDBx:U22>0.3401</PDBx:U22>
         <PDBx:U23>-0.0326</PDBx:U23>
         <PDBx:U33>0.5325</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.6301</PDBx:U11>
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         <PDBx:U23>-0.0812</PDBx:U23>
         <PDBx:U33>0.5908</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.7329</PDBx:U11>
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         <PDBx:U23>-0.1092</PDBx:U23>
         <PDBx:U33>0.7236</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:U11>0.7874</PDBx:U11>
         <PDBx:U12>-0.0932</PDBx:U12>
         <PDBx:U13>-0.0702</PDBx:U13>
         <PDBx:U22>0.5448</PDBx:U22>
         <PDBx:U23>-0.1222</PDBx:U23>
         <PDBx:U33>0.7451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>396</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>96</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.6665</PDBx:U11>
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         <PDBx:U13>-0.0193</PDBx:U13>
         <PDBx:U22>0.3637</PDBx:U22>
         <PDBx:U23>-0.0193</PDBx:U23>
         <PDBx:U33>0.5363</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>-0.0025</PDBx:U13>
         <PDBx:U22>0.3921</PDBx:U22>
         <PDBx:U23>-0.0071</PDBx:U23>
         <PDBx:U33>0.6013</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.3652</PDBx:U22>
         <PDBx:U23>0.0280</PDBx:U23>
         <PDBx:U33>0.5562</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.8460</PDBx:U11>
         <PDBx:U12>-0.0305</PDBx:U12>
         <PDBx:U13>0.0117</PDBx:U13>
         <PDBx:U22>0.3814</PDBx:U22>
         <PDBx:U23>0.0475</PDBx:U23>
         <PDBx:U33>0.5932</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2584">
         <PDBx:U11>0.8669</PDBx:U11>
         <PDBx:U12>-0.1070</PDBx:U12>
         <PDBx:U13>0.0129</PDBx:U13>
         <PDBx:U22>0.4769</PDBx:U22>
         <PDBx:U23>-0.0148</PDBx:U23>
         <PDBx:U33>0.7034</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2585">
         <PDBx:U11>0.9536</PDBx:U11>
         <PDBx:U12>-0.1412</PDBx:U12>
         <PDBx:U13>0.0091</PDBx:U13>
         <PDBx:U22>0.5855</PDBx:U22>
         <PDBx:U23>-0.0528</PDBx:U23>
         <PDBx:U33>0.8390</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2586">
         <PDBx:U11>1.1225</PDBx:U11>
         <PDBx:U12>-0.1325</PDBx:U12>
         <PDBx:U13>0.0030</PDBx:U13>
         <PDBx:U22>0.7178</PDBx:U22>
         <PDBx:U23>-0.0719</PDBx:U23>
         <PDBx:U33>1.0043</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2587">
         <PDBx:U11>1.0905</PDBx:U11>
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         <PDBx:U13>-0.0153</PDBx:U13>
         <PDBx:U22>0.7390</PDBx:U22>
         <PDBx:U23>-0.0948</PDBx:U23>
         <PDBx:U33>1.0182</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2588">
         <PDBx:U11>1.2538</PDBx:U11>
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         <PDBx:U13>0.0153</PDBx:U13>
         <PDBx:U22>0.7767</PDBx:U22>
         <PDBx:U23>-0.0617</PDBx:U23>
         <PDBx:U33>1.0922</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>397</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>97</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U22>0.3245</PDBx:U22>
         <PDBx:U23>0.0359</PDBx:U23>
         <PDBx:U33>0.4785</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.7416</PDBx:U11>
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         <PDBx:U13>-0.0173</PDBx:U13>
         <PDBx:U22>0.3782</PDBx:U22>
         <PDBx:U23>0.0653</PDBx:U23>
         <PDBx:U33>0.5150</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.7208</PDBx:U11>
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         <PDBx:U22>0.3573</PDBx:U22>
         <PDBx:U23>0.0610</PDBx:U23>
         <PDBx:U33>0.4992</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2592">
         <PDBx:U11>0.6564</PDBx:U11>
         <PDBx:U12>0.1122</PDBx:U12>
         <PDBx:U13>-0.0320</PDBx:U13>
         <PDBx:U22>0.3569</PDBx:U22>
         <PDBx:U23>0.0624</PDBx:U23>
         <PDBx:U33>0.4602</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2593">
         <PDBx:U11>0.6647</PDBx:U11>
         <PDBx:U12>0.0479</PDBx:U12>
         <PDBx:U13>-0.0246</PDBx:U13>
         <PDBx:U22>0.3763</PDBx:U22>
         <PDBx:U23>0.0786</PDBx:U23>
         <PDBx:U33>0.4552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2594">
         <PDBx:U11>0.7386</PDBx:U11>
         <PDBx:U12>0.0064</PDBx:U12>
         <PDBx:U13>-0.0148</PDBx:U13>
         <PDBx:U22>0.4521</PDBx:U22>
         <PDBx:U23>0.0814</PDBx:U23>
         <PDBx:U33>0.5214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2595">
         <PDBx:U11>0.8319</PDBx:U11>
         <PDBx:U12>0.0004</PDBx:U12>
         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.4918</PDBx:U22>
         <PDBx:U23>0.1070</PDBx:U23>
         <PDBx:U33>0.5633</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2596">
         <PDBx:U11>0.6820</PDBx:U11>
         <PDBx:U12>-0.0319</PDBx:U12>
         <PDBx:U13>-0.0097</PDBx:U13>
         <PDBx:U22>0.4428</PDBx:U22>
         <PDBx:U23>0.0608</PDBx:U23>
         <PDBx:U33>0.5019</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2597">
         <PDBx:U11>0.8159</PDBx:U11>
         <PDBx:U12>-0.0428</PDBx:U12>
         <PDBx:U13>0.0058</PDBx:U13>
         <PDBx:U22>0.4909</PDBx:U22>
         <PDBx:U23>0.1005</PDBx:U23>
         <PDBx:U33>0.5497</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2598">
         <PDBx:U11>0.7385</PDBx:U11>
         <PDBx:U12>-0.0623</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.4769</PDBx:U22>
         <PDBx:U23>0.0708</PDBx:U23>
         <PDBx:U33>0.5311</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>398</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>98</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2599">
         <PDBx:U11>0.7777</PDBx:U11>
         <PDBx:U12>0.0976</PDBx:U12>
         <PDBx:U13>-0.0159</PDBx:U13>
         <PDBx:U22>0.3416</PDBx:U22>
         <PDBx:U23>0.0525</PDBx:U23>
         <PDBx:U33>0.5340</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2600">
         <PDBx:U11>0.7992</PDBx:U11>
         <PDBx:U12>0.1344</PDBx:U12>
         <PDBx:U13>-0.0162</PDBx:U13>
         <PDBx:U22>0.3534</PDBx:U22>
         <PDBx:U23>0.0436</PDBx:U23>
         <PDBx:U33>0.5578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2601">
         <PDBx:U11>0.7975</PDBx:U11>
         <PDBx:U12>0.1779</PDBx:U12>
         <PDBx:U13>-0.0238</PDBx:U13>
         <PDBx:U22>0.3829</PDBx:U22>
         <PDBx:U23>0.0647</PDBx:U23>
         <PDBx:U33>0.5648</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2602">
         <PDBx:U11>0.7504</PDBx:U11>
         <PDBx:U12>0.1910</PDBx:U12>
         <PDBx:U13>-0.0279</PDBx:U13>
         <PDBx:U22>0.3106</PDBx:U22>
         <PDBx:U23>0.0922</PDBx:U23>
         <PDBx:U33>0.4981</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2603">
         <PDBx:U11>0.9046</PDBx:U11>
         <PDBx:U12>0.1346</PDBx:U12>
         <PDBx:U13>-0.0039</PDBx:U13>
         <PDBx:U22>0.3602</PDBx:U22>
         <PDBx:U23>0.0396</PDBx:U23>
         <PDBx:U33>0.6309</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2604">
         <PDBx:U11>0.9356</PDBx:U11>
         <PDBx:U12>0.0867</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.3662</PDBx:U22>
         <PDBx:U23>0.0298</PDBx:U23>
         <PDBx:U33>0.6547</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2605">
         <PDBx:U11>0.8724</PDBx:U11>
         <PDBx:U12>0.0686</PDBx:U12>
         <PDBx:U13>-0.0029</PDBx:U13>
         <PDBx:U22>0.3579</PDBx:U22>
         <PDBx:U23>0.0472</PDBx:U23>
         <PDBx:U33>0.6024</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>399</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>99</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2606">
         <PDBx:U11>0.7719</PDBx:U11>
         <PDBx:U12>0.1992</PDBx:U12>
         <PDBx:U13>-0.0258</PDBx:U13>
         <PDBx:U22>0.4115</PDBx:U22>
         <PDBx:U23>0.0513</PDBx:U23>
         <PDBx:U33>0.5676</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2607">
         <PDBx:U11>0.6959</PDBx:U11>
         <PDBx:U12>0.2334</PDBx:U12>
         <PDBx:U13>-0.0310</PDBx:U13>
         <PDBx:U22>0.3835</PDBx:U22>
         <PDBx:U23>0.0616</PDBx:U23>
         <PDBx:U33>0.5178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2608">
         <PDBx:U11>0.6888</PDBx:U11>
         <PDBx:U12>0.2294</PDBx:U12>
         <PDBx:U13>-0.0430</PDBx:U13>
         <PDBx:U22>0.4484</PDBx:U22>
         <PDBx:U23>0.0772</PDBx:U23>
         <PDBx:U33>0.5307</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2609">
         <PDBx:U11>0.6683</PDBx:U11>
         <PDBx:U12>0.2456</PDBx:U12>
         <PDBx:U13>-0.0488</PDBx:U13>
         <PDBx:U22>0.4776</PDBx:U22>
         <PDBx:U23>0.0822</PDBx:U23>
         <PDBx:U33>0.5391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>400</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>100</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2610">
         <PDBx:U11>0.6354</PDBx:U11>
         <PDBx:U12>0.1973</PDBx:U12>
         <PDBx:U13>-0.0451</PDBx:U13>
         <PDBx:U22>0.4086</PDBx:U22>
         <PDBx:U23>0.0788</PDBx:U23>
         <PDBx:U33>0.4703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2611">
         <PDBx:U11>0.5633</PDBx:U11>
         <PDBx:U12>0.1879</PDBx:U12>
         <PDBx:U13>-0.0541</PDBx:U13>
         <PDBx:U22>0.4035</PDBx:U22>
         <PDBx:U23>0.0905</PDBx:U23>
         <PDBx:U33>0.4151</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2612">
         <PDBx:U11>0.4423</PDBx:U11>
         <PDBx:U12>0.1559</PDBx:U12>
         <PDBx:U13>-0.0514</PDBx:U13>
         <PDBx:U22>0.3454</PDBx:U22>
         <PDBx:U23>0.0715</PDBx:U23>
         <PDBx:U33>0.3281</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2613">
         <PDBx:U11>0.4495</PDBx:U11>
         <PDBx:U12>0.1309</PDBx:U12>
         <PDBx:U13>-0.0460</PDBx:U13>
         <PDBx:U22>0.3316</PDBx:U22>
         <PDBx:U23>0.0548</PDBx:U23>
         <PDBx:U33>0.3348</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2614">
         <PDBx:U11>0.6514</PDBx:U11>
         <PDBx:U12>0.1701</PDBx:U12>
         <PDBx:U13>-0.0562</PDBx:U13>
         <PDBx:U22>0.4501</PDBx:U22>
         <PDBx:U23>0.1135</PDBx:U23>
         <PDBx:U33>0.4636</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2615">
         <PDBx:U11>0.7760</PDBx:U11>
         <PDBx:U12>0.1989</PDBx:U12>
         <PDBx:U13>-0.0618</PDBx:U13>
         <PDBx:U22>0.5180</PDBx:U22>
         <PDBx:U23>0.1373</PDBx:U23>
         <PDBx:U33>0.5568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2616">
         <PDBx:U11>0.8207</PDBx:U11>
         <PDBx:U12>0.2192</PDBx:U12>
         <PDBx:U13>-0.0757</PDBx:U13>
         <PDBx:U22>0.6322</PDBx:U22>
         <PDBx:U23>0.1425</PDBx:U23>
         <PDBx:U33>0.6357</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2617">
         <PDBx:U11>0.9801</PDBx:U11>
         <PDBx:U12>0.2371</PDBx:U12>
         <PDBx:U13>-0.0849</PDBx:U13>
         <PDBx:U22>0.7448</PDBx:U22>
         <PDBx:U23>0.1654</PDBx:U23>
         <PDBx:U33>0.7725</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2618">
         <PDBx:U11>1.0320</PDBx:U11>
         <PDBx:U12>0.2550</PDBx:U12>
         <PDBx:U13>-0.1027</PDBx:U13>
         <PDBx:U22>0.8582</PDBx:U22>
         <PDBx:U23>0.1703</PDBx:U23>
         <PDBx:U33>0.8551</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>401</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>101</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2619">
         <PDBx:U11>0.4113</PDBx:U11>
         <PDBx:U12>0.1578</PDBx:U12>
         <PDBx:U13>-0.0569</PDBx:U13>
         <PDBx:U22>0.3912</PDBx:U22>
         <PDBx:U23>0.0732</PDBx:U23>
         <PDBx:U33>0.3288</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2620">
         <PDBx:U11>0.3692</PDBx:U11>
         <PDBx:U12>0.1281</PDBx:U12>
         <PDBx:U13>-0.0544</PDBx:U13>
         <PDBx:U22>0.4083</PDBx:U22>
         <PDBx:U23>0.0579</PDBx:U23>
         <PDBx:U33>0.3230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2621">
         <PDBx:U11>0.3702</PDBx:U11>
         <PDBx:U12>0.1016</PDBx:U12>
         <PDBx:U13>-0.0562</PDBx:U13>
         <PDBx:U22>0.4367</PDBx:U22>
         <PDBx:U23>0.0658</PDBx:U23>
         <PDBx:U33>0.3246</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2622">
         <PDBx:U11>0.3545</PDBx:U11>
         <PDBx:U12>0.1149</PDBx:U12>
         <PDBx:U13>-0.0630</PDBx:U13>
         <PDBx:U22>0.4544</PDBx:U22>
         <PDBx:U23>0.0786</PDBx:U23>
         <PDBx:U33>0.3074</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2623">
         <PDBx:U11>0.3041</PDBx:U11>
         <PDBx:U12>0.1410</PDBx:U12>
         <PDBx:U13>-0.0516</PDBx:U13>
         <PDBx:U22>0.4078</PDBx:U22>
         <PDBx:U23>0.0462</PDBx:U23>
         <PDBx:U33>0.3000</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2624">
         <PDBx:U11>0.3272</PDBx:U11>
         <PDBx:U12>0.1552</PDBx:U12>
         <PDBx:U13>-0.0433</PDBx:U13>
         <PDBx:U22>0.4121</PDBx:U22>
         <PDBx:U23>0.0329</PDBx:U23>
         <PDBx:U33>0.3236</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2625">
         <PDBx:U11>0.2724</PDBx:U11>
         <PDBx:U12>0.1466</PDBx:U12>
         <PDBx:U13>-0.0323</PDBx:U13>
         <PDBx:U22>0.4025</PDBx:U22>
         <PDBx:U23>0.0208</PDBx:U23>
         <PDBx:U33>0.3004</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2626">
         <PDBx:U11>0.2763</PDBx:U11>
         <PDBx:U12>0.1384</PDBx:U12>
         <PDBx:U13>-0.0440</PDBx:U13>
         <PDBx:U22>0.3338</PDBx:U22>
         <PDBx:U23>0.0218</PDBx:U23>
         <PDBx:U33>0.2618</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>402</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>102</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2627">
         <PDBx:U11>0.3545</PDBx:U11>
         <PDBx:U12>0.0633</PDBx:U12>
         <PDBx:U13>-0.0500</PDBx:U13>
         <PDBx:U22>0.4088</PDBx:U22>
         <PDBx:U23>0.0557</PDBx:U23>
         <PDBx:U33>0.3120</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2628">
         <PDBx:U11>0.3298</PDBx:U11>
         <PDBx:U12>0.0322</PDBx:U12>
         <PDBx:U13>-0.0459</PDBx:U13>
         <PDBx:U22>0.4068</PDBx:U22>
         <PDBx:U23>0.0580</PDBx:U23>
         <PDBx:U33>0.2880</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2629">
         <PDBx:U11>0.2839</PDBx:U11>
         <PDBx:U12>0.0163</PDBx:U12>
         <PDBx:U13>-0.0447</PDBx:U13>
         <PDBx:U22>0.4434</PDBx:U22>
         <PDBx:U23>0.0413</PDBx:U23>
         <PDBx:U33>0.2988</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2630">
         <PDBx:U11>0.2121</PDBx:U11>
         <PDBx:U12>-0.0122</PDBx:U12>
         <PDBx:U13>-0.0399</PDBx:U13>
         <PDBx:U22>0.3837</PDBx:U22>
         <PDBx:U23>0.0231</PDBx:U23>
         <PDBx:U33>0.2598</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2631">
         <PDBx:U11>0.3448</PDBx:U11>
         <PDBx:U12>-0.0032</PDBx:U12>
         <PDBx:U13>-0.0358</PDBx:U13>
         <PDBx:U22>0.3661</PDBx:U22>
         <PDBx:U23>0.0517</PDBx:U23>
         <PDBx:U33>0.2844</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2632">
         <PDBx:U11>0.4257</PDBx:U11>
         <PDBx:U12>-0.0373</PDBx:U12>
         <PDBx:U13>-0.0250</PDBx:U13>
         <PDBx:U22>0.4457</PDBx:U22>
         <PDBx:U23>0.0563</PDBx:U23>
         <PDBx:U33>0.3472</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2633">
         <PDBx:U11>0.5622</PDBx:U11>
         <PDBx:U12>-0.0600</PDBx:U12>
         <PDBx:U13>-0.0125</PDBx:U13>
         <PDBx:U22>0.5004</PDBx:U22>
         <PDBx:U23>0.0585</PDBx:U23>
         <PDBx:U33>0.4446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2634">
         <PDBx:U11>0.4582</PDBx:U11>
         <PDBx:U12>-0.0699</PDBx:U12>
         <PDBx:U13>-0.0186</PDBx:U13>
         <PDBx:U22>0.5470</PDBx:U22>
         <PDBx:U23>0.0330</PDBx:U23>
         <PDBx:U33>0.4363</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>403</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>103</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2635">
         <PDBx:U11>0.2114</PDBx:U11>
         <PDBx:U12>0.0355</PDBx:U12>
         <PDBx:U13>-0.0498</PDBx:U13>
         <PDBx:U22>0.4278</PDBx:U22>
         <PDBx:U23>0.0458</PDBx:U23>
         <PDBx:U33>0.2425</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2636">
         <PDBx:U11>0.2525</PDBx:U11>
         <PDBx:U12>0.0176</PDBx:U12>
         <PDBx:U13>-0.0378</PDBx:U13>
         <PDBx:U22>0.5050</PDBx:U22>
         <PDBx:U23>0.0255</PDBx:U23>
         <PDBx:U33>0.3233</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2637">
         <PDBx:U11>0.2453</PDBx:U11>
         <PDBx:U12>-0.0168</PDBx:U12>
         <PDBx:U13>-0.0301</PDBx:U13>
         <PDBx:U22>0.5129</PDBx:U22>
         <PDBx:U23>0.0189</PDBx:U23>
         <PDBx:U33>0.3199</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2638">
         <PDBx:U11>0.2645</PDBx:U11>
         <PDBx:U12>-0.0290</PDBx:U12>
         <PDBx:U13>-0.0189</PDBx:U13>
         <PDBx:U22>0.4976</PDBx:U22>
         <PDBx:U23>0.0012</PDBx:U23>
         <PDBx:U33>0.3530</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2639">
         <PDBx:U11>0.2492</PDBx:U11>
         <PDBx:U12>0.0350</PDBx:U12>
         <PDBx:U13>-0.0344</PDBx:U13>
         <PDBx:U22>0.5082</PDBx:U22>
         <PDBx:U23>0.0248</PDBx:U23>
         <PDBx:U33>0.3164</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2640">
         <PDBx:U11>0.2657</PDBx:U11>
         <PDBx:U12>0.0541</PDBx:U12>
         <PDBx:U13>-0.0329</PDBx:U13>
         <PDBx:U22>0.5030</PDBx:U22>
         <PDBx:U23>0.0208</PDBx:U23>
         <PDBx:U33>0.3372</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2641">
         <PDBx:U11>0.2663</PDBx:U11>
         <PDBx:U12>0.0446</PDBx:U12>
         <PDBx:U13>-0.0225</PDBx:U13>
         <PDBx:U22>0.4954</PDBx:U22>
         <PDBx:U23>0.0082</PDBx:U23>
         <PDBx:U33>0.3464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2642">
         <PDBx:U11>0.2674</PDBx:U11>
         <PDBx:U12>0.0835</PDBx:U12>
         <PDBx:U13>-0.0417</PDBx:U13>
         <PDBx:U22>0.4939</PDBx:U22>
         <PDBx:U23>0.0324</PDBx:U23>
         <PDBx:U33>0.3239</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2643">
         <PDBx:U11>0.2096</PDBx:U11>
         <PDBx:U12>0.0585</PDBx:U12>
         <PDBx:U13>-0.0200</PDBx:U13>
         <PDBx:U22>0.4337</PDBx:U22>
         <PDBx:U23>0.0058</PDBx:U23>
         <PDBx:U33>0.2894</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2644">
         <PDBx:U11>0.2956</PDBx:U11>
         <PDBx:U12>0.0967</PDBx:U12>
         <PDBx:U13>-0.0368</PDBx:U13>
         <PDBx:U22>0.5090</PDBx:U22>
         <PDBx:U23>0.0258</PDBx:U23>
         <PDBx:U33>0.3582</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2645">
         <PDBx:U11>0.2136</PDBx:U11>
         <PDBx:U12>0.0807</PDBx:U12>
         <PDBx:U13>-0.0260</PDBx:U13>
         <PDBx:U22>0.4272</PDBx:U22>
         <PDBx:U23>0.0126</PDBx:U23>
         <PDBx:U33>0.2909</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>404</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>104</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2646">
         <PDBx:U11>0.2407</PDBx:U11>
         <PDBx:U12>-0.0262</PDBx:U12>
         <PDBx:U13>-0.0369</PDBx:U13>
         <PDBx:U22>0.5206</PDBx:U22>
         <PDBx:U23>0.0367</PDBx:U23>
         <PDBx:U33>0.2820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2647">
         <PDBx:U11>0.2889</PDBx:U11>
         <PDBx:U12>-0.0678</PDBx:U12>
         <PDBx:U13>-0.0235</PDBx:U13>
         <PDBx:U22>0.5729</PDBx:U22>
         <PDBx:U23>0.0291</PDBx:U23>
         <PDBx:U33>0.3233</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2648">
         <PDBx:U11>0.3155</PDBx:U11>
         <PDBx:U12>-0.0730</PDBx:U12>
         <PDBx:U13>-0.0203</PDBx:U13>
         <PDBx:U22>0.5211</PDBx:U22>
         <PDBx:U23>0.0508</PDBx:U23>
         <PDBx:U33>0.2757</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2649">
         <PDBx:U11>0.3641</PDBx:U11>
         <PDBx:U12>-0.0397</PDBx:U12>
         <PDBx:U13>-0.0320</PDBx:U13>
         <PDBx:U22>0.5240</PDBx:U22>
         <PDBx:U23>0.0735</PDBx:U23>
         <PDBx:U33>0.2820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2650">
         <PDBx:U11>0.2830</PDBx:U11>
         <PDBx:U12>-0.0709</PDBx:U12>
         <PDBx:U13>-0.0196</PDBx:U13>
         <PDBx:U22>0.6157</PDBx:U22>
         <PDBx:U23>0.0231</PDBx:U23>
         <PDBx:U33>0.3212</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>405</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>105</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2651">
         <PDBx:U11>0.3804</PDBx:U11>
         <PDBx:U12>-0.1154</PDBx:U12>
         <PDBx:U13>-0.0021</PDBx:U13>
         <PDBx:U22>0.5670</PDBx:U22>
         <PDBx:U23>0.0429</PDBx:U23>
         <PDBx:U33>0.3264</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2652">
         <PDBx:U11>0.4057</PDBx:U11>
         <PDBx:U12>-0.1248</PDBx:U12>
         <PDBx:U13>0.0057</PDBx:U13>
         <PDBx:U22>0.5101</PDBx:U22>
         <PDBx:U23>0.0646</PDBx:U23>
         <PDBx:U33>0.2764</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2653">
         <PDBx:U11>0.5109</PDBx:U11>
         <PDBx:U12>-0.0975</PDBx:U12>
         <PDBx:U13>-0.0090</PDBx:U13>
         <PDBx:U22>0.6006</PDBx:U22>
         <PDBx:U23>0.0979</PDBx:U23>
         <PDBx:U33>0.3139</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2654">
         <PDBx:U11>0.5834</PDBx:U11>
         <PDBx:U12>-0.0868</PDBx:U12>
         <PDBx:U13>-0.0106</PDBx:U13>
         <PDBx:U22>0.5944</PDBx:U22>
         <PDBx:U23>0.1244</PDBx:U23>
         <PDBx:U33>0.3211</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2655">
         <PDBx:U11>0.4327</PDBx:U11>
         <PDBx:U12>-0.1793</PDBx:U12>
         <PDBx:U13>0.0318</PDBx:U13>
         <PDBx:U22>0.5431</PDBx:U22>
         <PDBx:U23>0.0453</PDBx:U23>
         <PDBx:U33>0.3083</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2656">
         <PDBx:U11>0.3103</PDBx:U11>
         <PDBx:U12>-0.1931</PDBx:U12>
         <PDBx:U13>0.0351</PDBx:U13>
         <PDBx:U22>0.4842</PDBx:U22>
         <PDBx:U23>0.0095</PDBx:U23>
         <PDBx:U33>0.2773</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2657">
         <PDBx:U11>0.2948</PDBx:U11>
         <PDBx:U12>-0.1572</PDBx:U12>
         <PDBx:U13>0.0150</PDBx:U13>
         <PDBx:U22>0.5296</PDBx:U22>
         <PDBx:U23>0.0121</PDBx:U23>
         <PDBx:U33>0.2965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>406</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>106</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2658">
         <PDBx:U11>0.4679</PDBx:U11>
         <PDBx:U12>-0.0857</PDBx:U12>
         <PDBx:U13>-0.0210</PDBx:U13>
         <PDBx:U22>0.6323</PDBx:U22>
         <PDBx:U23>0.0958</PDBx:U23>
         <PDBx:U33>0.2889</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2659">
         <PDBx:U11>0.5466</PDBx:U11>
         <PDBx:U12>-0.0582</PDBx:U12>
         <PDBx:U13>-0.0411</PDBx:U13>
         <PDBx:U22>0.7099</PDBx:U22>
         <PDBx:U23>0.1247</PDBx:U23>
         <PDBx:U33>0.3101</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2660">
         <PDBx:U11>0.5184</PDBx:U11>
         <PDBx:U12>-0.0058</PDBx:U12>
         <PDBx:U13>-0.0664</PDBx:U13>
         <PDBx:U22>0.7186</PDBx:U22>
         <PDBx:U23>0.1297</PDBx:U23>
         <PDBx:U33>0.3148</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2661">
         <PDBx:U11>0.5731</PDBx:U11>
         <PDBx:U12>0.0197</PDBx:U12>
         <PDBx:U13>-0.0825</PDBx:U13>
         <PDBx:U22>0.7796</PDBx:U22>
         <PDBx:U23>0.1357</PDBx:U23>
         <PDBx:U33>0.3589</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2662">
         <PDBx:U11>0.5320</PDBx:U11>
         <PDBx:U12>-0.0861</PDBx:U12>
         <PDBx:U13>-0.0362</PDBx:U13>
         <PDBx:U22>0.7505</PDBx:U22>
         <PDBx:U23>0.1155</PDBx:U23>
         <PDBx:U33>0.2853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2663">
         <PDBx:U11>0.4500</PDBx:U11>
         <PDBx:U12>-0.0898</PDBx:U12>
         <PDBx:U13>-0.0355</PDBx:U13>
         <PDBx:U22>0.7677</PDBx:U22>
         <PDBx:U23>0.0826</PDBx:U23>
         <PDBx:U33>0.2899</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2664">
         <PDBx:U11>0.3311</PDBx:U11>
         <PDBx:U12>-0.0861</PDBx:U12>
         <PDBx:U13>-0.0320</PDBx:U13>
         <PDBx:U22>0.6752</PDBx:U22>
         <PDBx:U23>0.0647</PDBx:U23>
         <PDBx:U33>0.2342</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2665">
         <PDBx:U11>0.4383</PDBx:U11>
         <PDBx:U12>-0.0962</PDBx:U12>
         <PDBx:U13>-0.0370</PDBx:U13>
         <PDBx:U22>0.8017</PDBx:U22>
         <PDBx:U23>0.0733</PDBx:U23>
         <PDBx:U33>0.2855</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>407</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>107</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2666">
         <PDBx:U11>0.4670</PDBx:U11>
         <PDBx:U12>0.0078</PDBx:U12>
         <PDBx:U13>-0.0636</PDBx:U13>
         <PDBx:U22>0.6718</PDBx:U22>
         <PDBx:U23>0.1139</PDBx:U23>
         <PDBx:U33>0.3184</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2667">
         <PDBx:U11>0.4368</PDBx:U11>
         <PDBx:U12>0.0512</PDBx:U12>
         <PDBx:U13>-0.0773</PDBx:U13>
         <PDBx:U22>0.6656</PDBx:U22>
         <PDBx:U23>0.1095</PDBx:U23>
         <PDBx:U33>0.3280</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2668">
         <PDBx:U11>0.4388</PDBx:U11>
         <PDBx:U12>0.0729</PDBx:U12>
         <PDBx:U13>-0.0772</PDBx:U13>
         <PDBx:U22>0.6190</PDBx:U22>
         <PDBx:U23>0.1137</PDBx:U23>
         <PDBx:U33>0.3320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2669">
         <PDBx:U11>0.3438</PDBx:U11>
         <PDBx:U12>0.0658</PDBx:U12>
         <PDBx:U13>-0.0682</PDBx:U13>
         <PDBx:U22>0.5435</PDBx:U22>
         <PDBx:U23>0.0922</PDBx:U23>
         <PDBx:U33>0.2847</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2670">
         <PDBx:U11>0.3675</PDBx:U11>
         <PDBx:U12>0.0416</PDBx:U12>
         <PDBx:U13>-0.0665</PDBx:U13>
         <PDBx:U22>0.6703</PDBx:U22>
         <PDBx:U23>0.0775</PDBx:U23>
         <PDBx:U33>0.3338</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2671">
         <PDBx:U11>0.3527</PDBx:U11>
         <PDBx:U12>0.0700</PDBx:U12>
         <PDBx:U13>-0.0658</PDBx:U13>
         <PDBx:U22>0.6603</PDBx:U22>
         <PDBx:U23>0.0648</PDBx:U23>
         <PDBx:U33>0.3547</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2672">
         <PDBx:U11>0.4167</PDBx:U11>
         <PDBx:U12>0.0948</PDBx:U12>
         <PDBx:U13>-0.0838</PDBx:U13>
         <PDBx:U22>0.7184</PDBx:U22>
         <PDBx:U23>0.0782</PDBx:U23>
         <PDBx:U33>0.3951</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2673">
         <PDBx:U11>0.3284</PDBx:U11>
         <PDBx:U12>0.0517</PDBx:U12>
         <PDBx:U13>-0.0461</PDBx:U13>
         <PDBx:U22>0.6648</PDBx:U22>
         <PDBx:U23>0.0381</PDBx:U23>
         <PDBx:U33>0.3707</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>408</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>108</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2674">
         <PDBx:U11>0.5557</PDBx:U11>
         <PDBx:U12>0.0971</PDBx:U12>
         <PDBx:U13>-0.0848</PDBx:U13>
         <PDBx:U22>0.6616</PDBx:U22>
         <PDBx:U23>0.1377</PDBx:U23>
         <PDBx:U33>0.3979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2675">
         <PDBx:U11>0.5925</PDBx:U11>
         <PDBx:U12>0.1159</PDBx:U12>
         <PDBx:U13>-0.0808</PDBx:U13>
         <PDBx:U22>0.6376</PDBx:U22>
         <PDBx:U23>0.1368</PDBx:U23>
         <PDBx:U33>0.4337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2676">
         <PDBx:U11>0.6255</PDBx:U11>
         <PDBx:U12>0.1538</PDBx:U12>
         <PDBx:U13>-0.0912</PDBx:U13>
         <PDBx:U22>0.6724</PDBx:U22>
         <PDBx:U23>0.1341</PDBx:U23>
         <PDBx:U33>0.4912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2677">
         <PDBx:U11>0.6199</PDBx:U11>
         <PDBx:U12>0.1700</PDBx:U12>
         <PDBx:U13>-0.1032</PDBx:U13>
         <PDBx:U22>0.6372</PDBx:U22>
         <PDBx:U23>0.1515</PDBx:U23>
         <PDBx:U33>0.4609</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2678">
         <PDBx:U11>0.7313</PDBx:U11>
         <PDBx:U12>0.1013</PDBx:U12>
         <PDBx:U13>-0.0723</PDBx:U13>
         <PDBx:U22>0.6772</PDBx:U22>
         <PDBx:U23>0.1541</PDBx:U23>
         <PDBx:U33>0.5112</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2679">
         <PDBx:U11>0.8373</PDBx:U11>
         <PDBx:U12>0.1089</PDBx:U12>
         <PDBx:U13>-0.0636</PDBx:U13>
         <PDBx:U22>0.7125</PDBx:U22>
         <PDBx:U23>0.1474</PDBx:U23>
         <PDBx:U33>0.6133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2680">
         <PDBx:U11>0.7775</PDBx:U11>
         <PDBx:U12>0.0811</PDBx:U12>
         <PDBx:U13>-0.0519</PDBx:U13>
         <PDBx:U22>0.6804</PDBx:U22>
         <PDBx:U23>0.1157</PDBx:U23>
         <PDBx:U33>0.5994</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2681">
         <PDBx:U11>0.9776</PDBx:U11>
         <PDBx:U12>0.0943</PDBx:U12>
         <PDBx:U13>-0.0541</PDBx:U13>
         <PDBx:U22>0.7543</PDBx:U22>
         <PDBx:U23>0.1665</PDBx:U23>
         <PDBx:U33>0.6915</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>409</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>109</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2682">
         <PDBx:U11>0.5774</PDBx:U11>
         <PDBx:U12>0.1613</PDBx:U12>
         <PDBx:U13>-0.0839</PDBx:U13>
         <PDBx:U22>0.6580</PDBx:U22>
         <PDBx:U23>0.1104</PDBx:U23>
         <PDBx:U33>0.4937</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2683">
         <PDBx:U11>0.5443</PDBx:U11>
         <PDBx:U12>0.1863</PDBx:U12>
         <PDBx:U13>-0.0859</PDBx:U13>
         <PDBx:U22>0.6368</PDBx:U22>
         <PDBx:U23>0.1015</PDBx:U23>
         <PDBx:U33>0.4903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2684">
         <PDBx:U11>0.5876</PDBx:U11>
         <PDBx:U12>0.2059</PDBx:U12>
         <PDBx:U13>-0.0788</PDBx:U13>
         <PDBx:U22>0.6313</PDBx:U22>
         <PDBx:U23>0.0976</PDBx:U23>
         <PDBx:U33>0.5300</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2685">
         <PDBx:U11>0.5535</PDBx:U11>
         <PDBx:U12>0.1978</PDBx:U12>
         <PDBx:U13>-0.0698</PDBx:U13>
         <PDBx:U22>0.5708</PDBx:U22>
         <PDBx:U23>0.0913</PDBx:U23>
         <PDBx:U33>0.4859</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2686">
         <PDBx:U11>0.4717</PDBx:U11>
         <PDBx:U12>0.1747</PDBx:U12>
         <PDBx:U13>-0.0768</PDBx:U13>
         <PDBx:U22>0.6322</PDBx:U22>
         <PDBx:U23>0.0768</PDBx:U23>
         <PDBx:U33>0.4685</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2687">
         <PDBx:U11>0.5029</PDBx:U11>
         <PDBx:U12>0.1559</PDBx:U12>
         <PDBx:U13>-0.0791</PDBx:U13>
         <PDBx:U22>0.7129</PDBx:U22>
         <PDBx:U23>0.0730</PDBx:U23>
         <PDBx:U33>0.5105</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2688">
         <PDBx:U11>0.4469</PDBx:U11>
         <PDBx:U12>0.1414</PDBx:U12>
         <PDBx:U13>-0.0642</PDBx:U13>
         <PDBx:U22>0.6972</PDBx:U22>
         <PDBx:U23>0.0487</PDBx:U23>
         <PDBx:U33>0.4956</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2689">
         <PDBx:U11>0.5211</PDBx:U11>
         <PDBx:U12>0.1730</PDBx:U12>
         <PDBx:U13>-0.0983</PDBx:U13>
         <PDBx:U22>0.7305</PDBx:U22>
         <PDBx:U23>0.0890</PDBx:U23>
         <PDBx:U33>0.5105</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>410</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>110</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2690">
         <PDBx:U11>0.6515</PDBx:U11>
         <PDBx:U12>0.2319</PDBx:U12>
         <PDBx:U13>-0.0838</PDBx:U13>
         <PDBx:U22>0.6836</PDBx:U22>
         <PDBx:U23>0.0997</PDBx:U23>
         <PDBx:U33>0.6032</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2691">
         <PDBx:U11>0.6883</PDBx:U11>
         <PDBx:U12>0.2506</PDBx:U12>
         <PDBx:U13>-0.0742</PDBx:U13>
         <PDBx:U22>0.6841</PDBx:U22>
         <PDBx:U23>0.0901</PDBx:U23>
         <PDBx:U33>0.6448</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2692">
         <PDBx:U11>0.5938</PDBx:U11>
         <PDBx:U12>0.2556</PDBx:U12>
         <PDBx:U13>-0.0657</PDBx:U13>
         <PDBx:U22>0.6428</PDBx:U22>
         <PDBx:U23>0.0679</PDBx:U23>
         <PDBx:U33>0.5974</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2693">
         <PDBx:U11>0.4873</PDBx:U11>
         <PDBx:U12>0.2444</PDBx:U12>
         <PDBx:U13>-0.0677</PDBx:U13>
         <PDBx:U22>0.5925</PDBx:U22>
         <PDBx:U23>0.0614</PDBx:U23>
         <PDBx:U33>0.5177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2694">
         <PDBx:U11>0.8173</PDBx:U11>
         <PDBx:U12>0.2755</PDBx:U12>
         <PDBx:U13>-0.0829</PDBx:U13>
         <PDBx:U22>0.7526</PDBx:U22>
         <PDBx:U23>0.1080</PDBx:U23>
         <PDBx:U33>0.7523</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2695">
         <PDBx:U11>0.8904</PDBx:U11>
         <PDBx:U12>0.2934</PDBx:U12>
         <PDBx:U13>-0.1001</PDBx:U13>
         <PDBx:U22>0.8574</PDBx:U22>
         <PDBx:U23>0.1173</PDBx:U23>
         <PDBx:U33>0.8481</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2696">
         <PDBx:U11>0.8967</PDBx:U11>
         <PDBx:U12>0.2946</PDBx:U12>
         <PDBx:U13>-0.0994</PDBx:U13>
         <PDBx:U22>0.9263</PDBx:U22>
         <PDBx:U23>0.1008</PDBx:U23>
         <PDBx:U33>0.8980</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2697">
         <PDBx:U11>0.9530</PDBx:U11>
         <PDBx:U12>0.3052</PDBx:U12>
         <PDBx:U13>-0.1146</PDBx:U13>
         <PDBx:U22>0.8779</PDBx:U22>
         <PDBx:U23>0.1417</PDBx:U23>
         <PDBx:U33>0.8835</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>411</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>111</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2698">
         <PDBx:U11>0.5509</PDBx:U11>
         <PDBx:U12>0.2625</PDBx:U12>
         <PDBx:U13>0.0089</PDBx:U13>
         <PDBx:U22>0.7290</PDBx:U22>
         <PDBx:U23>0.1762</PDBx:U23>
         <PDBx:U33>0.6684</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2699">
         <PDBx:U11>0.5571</PDBx:U11>
         <PDBx:U12>0.2638</PDBx:U12>
         <PDBx:U13>0.0128</PDBx:U13>
         <PDBx:U22>0.7688</PDBx:U22>
         <PDBx:U23>0.1589</PDBx:U23>
         <PDBx:U33>0.7059</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2700">
         <PDBx:U11>0.5989</PDBx:U11>
         <PDBx:U12>0.2794</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.8643</PDBx:U22>
         <PDBx:U23>0.1639</PDBx:U23>
         <PDBx:U33>0.7791</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2701">
         <PDBx:U11>0.5379</PDBx:U11>
         <PDBx:U12>0.2706</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.8495</PDBx:U22>
         <PDBx:U23>0.1499</PDBx:U23>
         <PDBx:U33>0.7459</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2702">
         <PDBx:U11>0.5932</PDBx:U11>
         <PDBx:U12>0.2749</PDBx:U12>
         <PDBx:U13>0.0322</PDBx:U13>
         <PDBx:U22>0.7617</PDBx:U22>
         <PDBx:U23>0.1507</PDBx:U23>
         <PDBx:U33>0.7442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2703">
         <PDBx:U11>0.6716</PDBx:U11>
         <PDBx:U12>0.3041</PDBx:U12>
         <PDBx:U13>0.0369</PDBx:U13>
         <PDBx:U22>0.8059</PDBx:U22>
         <PDBx:U23>0.1645</PDBx:U23>
         <PDBx:U33>0.8240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2704">
         <PDBx:U11>0.6989</PDBx:U11>
         <PDBx:U12>0.3127</PDBx:U12>
         <PDBx:U13>0.0572</PDBx:U13>
         <PDBx:U22>0.7855</PDBx:U22>
         <PDBx:U23>0.1513</PDBx:U23>
         <PDBx:U33>0.8478</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2705">
         <PDBx:U11>0.7118</PDBx:U11>
         <PDBx:U12>0.3129</PDBx:U12>
         <PDBx:U13>0.0658</PDBx:U13>
         <PDBx:U22>0.8358</PDBx:U22>
         <PDBx:U23>0.1336</PDBx:U23>
         <PDBx:U33>0.8880</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2706">
         <PDBx:U11>0.8157</PDBx:U11>
         <PDBx:U12>0.3363</PDBx:U12>
         <PDBx:U13>0.0722</PDBx:U13>
         <PDBx:U22>0.9571</PDBx:U22>
         <PDBx:U23>0.1318</PDBx:U23>
         <PDBx:U33>1.0209</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2707">
         <PDBx:U11>0.8226</PDBx:U11>
         <PDBx:U12>0.3633</PDBx:U12>
         <PDBx:U13>0.0699</PDBx:U13>
         <PDBx:U22>0.9453</PDBx:U22>
         <PDBx:U23>0.1467</PDBx:U23>
         <PDBx:U33>1.0328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2708">
         <PDBx:U11>0.8486</PDBx:U11>
         <PDBx:U12>0.3329</PDBx:U12>
         <PDBx:U13>0.0816</PDBx:U13>
         <PDBx:U22>1.0257</PDBx:U22>
         <PDBx:U23>0.1157</PDBx:U23>
         <PDBx:U33>1.0791</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>412</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>112</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2709">
         <PDBx:U11>0.6985</PDBx:U11>
         <PDBx:U12>0.3019</PDBx:U12>
         <PDBx:U13>-0.0068</PDBx:U13>
         <PDBx:U22>0.9568</PDBx:U22>
         <PDBx:U23>0.1845</PDBx:U23>
         <PDBx:U33>0.8758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2710">
         <PDBx:U11>0.7391</PDBx:U11>
         <PDBx:U12>0.3200</PDBx:U12>
         <PDBx:U13>-0.0209</PDBx:U13>
         <PDBx:U22>1.0486</PDBx:U22>
         <PDBx:U23>0.1916</PDBx:U23>
         <PDBx:U33>0.9470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2711">
         <PDBx:U11>0.7260</PDBx:U11>
         <PDBx:U12>0.3026</PDBx:U12>
         <PDBx:U13>-0.0404</PDBx:U13>
         <PDBx:U22>1.0934</PDBx:U22>
         <PDBx:U23>0.1868</PDBx:U23>
         <PDBx:U33>0.9384</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2712">
         <PDBx:U11>0.7597</PDBx:U11>
         <PDBx:U12>0.3064</PDBx:U12>
         <PDBx:U13>-0.0512</PDBx:U13>
         <PDBx:U22>1.1806</PDBx:U22>
         <PDBx:U23>0.1810</PDBx:U23>
         <PDBx:U33>1.0069</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2713">
         <PDBx:U11>0.8039</PDBx:U11>
         <PDBx:U12>0.3485</PDBx:U12>
         <PDBx:U13>-0.0254</PDBx:U13>
         <PDBx:U22>1.0880</PDBx:U22>
         <PDBx:U23>0.2174</PDBx:U23>
         <PDBx:U33>1.0029</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2714">
         <PDBx:U11>0.8418</PDBx:U11>
         <PDBx:U12>0.3692</PDBx:U12>
         <PDBx:U13>-0.0070</PDBx:U13>
         <PDBx:U22>1.0702</PDBx:U22>
         <PDBx:U23>0.2192</PDBx:U23>
         <PDBx:U33>1.0432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2715">
         <PDBx:U11>0.7850</PDBx:U11>
         <PDBx:U12>0.3702</PDBx:U12>
         <PDBx:U13>0.0072</PDBx:U13>
         <PDBx:U22>1.0128</PDBx:U22>
         <PDBx:U23>0.2013</PDBx:U23>
         <PDBx:U33>1.0062</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2716">
         <PDBx:U11>0.9179</PDBx:U11>
         <PDBx:U12>0.3852</PDBx:U12>
         <PDBx:U13>-0.0064</PDBx:U13>
         <PDBx:U22>1.0966</PDBx:U22>
         <PDBx:U23>0.2401</PDBx:U23>
         <PDBx:U33>1.0978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>413</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>113</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2717">
         <PDBx:U11>0.6663</PDBx:U11>
         <PDBx:U12>0.2830</PDBx:U12>
         <PDBx:U13>-0.0445</PDBx:U13>
         <PDBx:U22>1.0222</PDBx:U22>
         <PDBx:U23>0.1877</PDBx:U23>
         <PDBx:U33>0.8446</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2718">
         <PDBx:U11>0.6540</PDBx:U11>
         <PDBx:U12>0.2650</PDBx:U12>
         <PDBx:U13>-0.0613</PDBx:U13>
         <PDBx:U22>1.0567</PDBx:U22>
         <PDBx:U23>0.1798</PDBx:U23>
         <PDBx:U33>0.8294</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2719">
         <PDBx:U11>0.6264</PDBx:U11>
         <PDBx:U12>0.2408</PDBx:U12>
         <PDBx:U13>-0.0576</PDBx:U13>
         <PDBx:U22>1.0496</PDBx:U22>
         <PDBx:U23>0.1535</PDBx:U23>
         <PDBx:U33>0.8212</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2720">
         <PDBx:U11>0.6562</PDBx:U11>
         <PDBx:U12>0.2281</PDBx:U12>
         <PDBx:U13>-0.0713</PDBx:U13>
         <PDBx:U22>1.1246</PDBx:U22>
         <PDBx:U23>0.1417</PDBx:U23>
         <PDBx:U33>0.8660</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2721">
         <PDBx:U11>0.6557</PDBx:U11>
         <PDBx:U12>0.2532</PDBx:U12>
         <PDBx:U13>-0.0631</PDBx:U13>
         <PDBx:U22>1.0362</PDBx:U22>
         <PDBx:U23>0.1883</PDBx:U23>
         <PDBx:U33>0.7878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2722">
         <PDBx:U11>0.7177</PDBx:U11>
         <PDBx:U12>0.2744</PDBx:U12>
         <PDBx:U13>-0.0657</PDBx:U13>
         <PDBx:U22>1.0725</PDBx:U22>
         <PDBx:U23>0.2165</PDBx:U23>
         <PDBx:U33>0.8283</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2723">
         <PDBx:U11>0.7619</PDBx:U11>
         <PDBx:U12>0.2612</PDBx:U12>
         <PDBx:U13>-0.0638</PDBx:U13>
         <PDBx:U22>1.0922</PDBx:U22>
         <PDBx:U23>0.2256</PDBx:U23>
         <PDBx:U33>0.8320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2724">
         <PDBx:U11>0.7453</PDBx:U11>
         <PDBx:U12>0.2562</PDBx:U12>
         <PDBx:U13>-0.0493</PDBx:U13>
         <PDBx:U22>1.0246</PDBx:U22>
         <PDBx:U23>0.2305</PDBx:U23>
         <PDBx:U33>0.7989</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2725">
         <PDBx:U11>0.8009</PDBx:U11>
         <PDBx:U12>0.2552</PDBx:U12>
         <PDBx:U13>-0.0783</PDBx:U13>
         <PDBx:U22>1.1683</PDBx:U22>
         <PDBx:U23>0.2273</PDBx:U23>
         <PDBx:U33>0.8553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>414</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>114</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2726">
         <PDBx:U11>0.5391</PDBx:U11>
         <PDBx:U12>0.2342</PDBx:U12>
         <PDBx:U13>-0.0392</PDBx:U13>
         <PDBx:U22>0.9257</PDBx:U22>
         <PDBx:U23>0.1445</PDBx:U23>
         <PDBx:U33>0.7324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2727">
         <PDBx:U11>0.4685</PDBx:U11>
         <PDBx:U12>0.2123</PDBx:U12>
         <PDBx:U13>-0.0331</PDBx:U13>
         <PDBx:U22>0.8660</PDBx:U22>
         <PDBx:U23>0.1221</PDBx:U23>
         <PDBx:U33>0.6785</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2728">
         <PDBx:U11>0.5060</PDBx:U11>
         <PDBx:U12>0.2179</PDBx:U12>
         <PDBx:U13>-0.0345</PDBx:U13>
         <PDBx:U22>0.9450</PDBx:U22>
         <PDBx:U23>0.1137</PDBx:U23>
         <PDBx:U33>0.7631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2729">
         <PDBx:U11>0.4862</PDBx:U11>
         <PDBx:U12>0.1982</PDBx:U12>
         <PDBx:U13>-0.0332</PDBx:U13>
         <PDBx:U22>0.9456</PDBx:U22>
         <PDBx:U23>0.0962</PDBx:U23>
         <PDBx:U33>0.7642</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>415</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>115</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2730">
         <PDBx:U11>0.5535</PDBx:U11>
         <PDBx:U12>0.2449</PDBx:U12>
         <PDBx:U13>-0.0364</PDBx:U13>
         <PDBx:U22>1.0046</PDBx:U22>
         <PDBx:U23>0.1267</PDBx:U23>
         <PDBx:U33>0.8300</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2731">
         <PDBx:U11>0.5782</PDBx:U11>
         <PDBx:U12>0.2533</PDBx:U12>
         <PDBx:U13>-0.0377</PDBx:U13>
         <PDBx:U22>1.0754</PDBx:U22>
         <PDBx:U23>0.1204</PDBx:U23>
         <PDBx:U33>0.9057</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2732">
         <PDBx:U11>0.5489</PDBx:U11>
         <PDBx:U12>0.2418</PDBx:U12>
         <PDBx:U13>-0.0603</PDBx:U13>
         <PDBx:U22>1.1043</PDBx:U22>
         <PDBx:U23>0.1152</PDBx:U23>
         <PDBx:U33>0.8989</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2733">
         <PDBx:U11>0.5009</PDBx:U11>
         <PDBx:U12>0.2409</PDBx:U12>
         <PDBx:U13>-0.0635</PDBx:U13>
         <PDBx:U22>1.1019</PDBx:U22>
         <PDBx:U23>0.1069</PDBx:U23>
         <PDBx:U33>0.8987</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2734">
         <PDBx:U11>0.5967</PDBx:U11>
         <PDBx:U12>0.2884</PDBx:U12>
         <PDBx:U13>-0.0345</PDBx:U13>
         <PDBx:U22>1.0911</PDBx:U22>
         <PDBx:U23>0.1365</PDBx:U23>
         <PDBx:U33>0.9397</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2735">
         <PDBx:U11>0.5841</PDBx:U11>
         <PDBx:U12>0.3018</PDBx:U12>
         <PDBx:U13>-0.0117</PDBx:U13>
         <PDBx:U22>1.0191</PDBx:U22>
         <PDBx:U23>0.1391</PDBx:U23>
         <PDBx:U33>0.9082</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2736">
         <PDBx:U11>0.6576</PDBx:U11>
         <PDBx:U12>0.3376</PDBx:U12>
         <PDBx:U13>-0.0075</PDBx:U13>
         <PDBx:U22>1.0921</PDBx:U22>
         <PDBx:U23>0.1513</PDBx:U23>
         <PDBx:U33>1.0043</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2737">
         <PDBx:U11>0.6670</PDBx:U11>
         <PDBx:U12>0.3501</PDBx:U12>
         <PDBx:U13>0.0167</PDBx:U13>
         <PDBx:U22>1.0408</PDBx:U22>
         <PDBx:U23>0.1488</PDBx:U23>
         <PDBx:U33>0.9968</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2738">
         <PDBx:U11>0.6943</PDBx:U11>
         <PDBx:U12>0.3852</PDBx:U12>
         <PDBx:U13>0.0237</PDBx:U13>
         <PDBx:U22>1.0703</PDBx:U22>
         <PDBx:U23>0.1555</PDBx:U23>
         <PDBx:U33>1.0528</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>416</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>116</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2739">
         <PDBx:U11>0.5380</PDBx:U11>
         <PDBx:U12>0.2327</PDBx:U12>
         <PDBx:U13>-0.0754</PDBx:U13>
         <PDBx:U22>1.0926</PDBx:U22>
         <PDBx:U23>0.1196</PDBx:U23>
         <PDBx:U33>0.8542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2740">
         <PDBx:U11>0.5210</PDBx:U11>
         <PDBx:U12>0.2217</PDBx:U12>
         <PDBx:U13>-0.0983</PDBx:U13>
         <PDBx:U22>1.1271</PDBx:U22>
         <PDBx:U23>0.1134</PDBx:U23>
         <PDBx:U33>0.8504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2741">
         <PDBx:U11>0.4761</PDBx:U11>
         <PDBx:U12>0.1932</PDBx:U12>
         <PDBx:U13>-0.0968</PDBx:U13>
         <PDBx:U22>1.1031</PDBx:U22>
         <PDBx:U23>0.0897</PDBx:U23>
         <PDBx:U33>0.8337</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2742">
         <PDBx:U11>0.4695</PDBx:U11>
         <PDBx:U12>0.1853</PDBx:U12>
         <PDBx:U13>-0.1134</PDBx:U13>
         <PDBx:U22>1.1460</PDBx:U22>
         <PDBx:U23>0.0818</PDBx:U23>
         <PDBx:U33>0.8586</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2743">
         <PDBx:U11>0.5502</PDBx:U11>
         <PDBx:U12>0.2163</PDBx:U12>
         <PDBx:U13>-0.1104</PDBx:U13>
         <PDBx:U22>1.1456</PDBx:U22>
         <PDBx:U23>0.1201</PDBx:U23>
         <PDBx:U33>0.8306</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2744">
         <PDBx:U11>1.0414</PDBx:U11>
         <PDBx:U12>0.2491</PDBx:U12>
         <PDBx:U13>-0.1173</PDBx:U13>
         <PDBx:U22>1.6232</PDBx:U22>
         <PDBx:U23>0.1517</PDBx:U23>
         <PDBx:U33>1.2942</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>417</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>117</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2745">
         <PDBx:U11>0.4618</PDBx:U11>
         <PDBx:U12>0.1778</PDBx:U12>
         <PDBx:U13>-0.0775</PDBx:U13>
         <PDBx:U22>1.0499</PDBx:U22>
         <PDBx:U23>0.0794</PDBx:U23>
         <PDBx:U33>0.8086</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2746">
         <PDBx:U11>0.4166</PDBx:U11>
         <PDBx:U12>0.1511</PDBx:U12>
         <PDBx:U13>-0.0728</PDBx:U13>
         <PDBx:U22>1.0153</PDBx:U22>
         <PDBx:U23>0.0597</PDBx:U23>
         <PDBx:U33>0.7889</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2747">
         <PDBx:U11>0.3770</PDBx:U11>
         <PDBx:U12>0.1537</PDBx:U12>
         <PDBx:U13>-0.0505</PDBx:U13>
         <PDBx:U22>0.9678</PDBx:U22>
         <PDBx:U23>0.0556</PDBx:U23>
         <PDBx:U33>0.7810</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2748">
         <PDBx:U11>0.3594</PDBx:U11>
         <PDBx:U12>0.1630</PDBx:U12>
         <PDBx:U13>-0.0330</PDBx:U13>
         <PDBx:U22>0.9081</PDBx:U22>
         <PDBx:U23>0.0602</PDBx:U23>
         <PDBx:U33>0.7406</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2749">
         <PDBx:U11>0.4399</PDBx:U11>
         <PDBx:U12>0.1281</PDBx:U12>
         <PDBx:U13>-0.0696</PDBx:U13>
         <PDBx:U22>1.0019</PDBx:U22>
         <PDBx:U23>0.0496</PDBx:U23>
         <PDBx:U33>0.7729</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2750">
         <PDBx:U11>0.4054</PDBx:U11>
         <PDBx:U12>0.1022</PDBx:U12>
         <PDBx:U13>-0.0640</PDBx:U13>
         <PDBx:U22>0.9734</PDBx:U22>
         <PDBx:U23>0.0319</PDBx:U23>
         <PDBx:U33>0.7663</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2751">
         <PDBx:U11>0.4861</PDBx:U11>
         <PDBx:U12>0.1254</PDBx:U12>
         <PDBx:U13>-0.0887</PDBx:U13>
         <PDBx:U22>1.0583</PDBx:U22>
         <PDBx:U23>0.0511</PDBx:U23>
         <PDBx:U33>0.7864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>418</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>118</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2752">
         <PDBx:U11>0.3427</PDBx:U11>
         <PDBx:U12>0.1450</PDBx:U12>
         <PDBx:U13>-0.0506</PDBx:U13>
         <PDBx:U22>0.9754</PDBx:U22>
         <PDBx:U23>0.0465</PDBx:U23>
         <PDBx:U33>0.7995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2753">
         <PDBx:U11>0.3267</PDBx:U11>
         <PDBx:U12>0.1477</PDBx:U12>
         <PDBx:U13>-0.0274</PDBx:U13>
         <PDBx:U22>0.9612</PDBx:U22>
         <PDBx:U23>0.0420</PDBx:U23>
         <PDBx:U33>0.8182</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2754">
         <PDBx:U11>0.3122</PDBx:U11>
         <PDBx:U12>0.1337</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>0.8950</PDBx:U22>
         <PDBx:U23>0.0348</PDBx:U23>
         <PDBx:U33>0.7747</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2755">
         <PDBx:U11>0.3292</PDBx:U11>
         <PDBx:U12>0.1089</PDBx:U12>
         <PDBx:U13>-0.0066</PDBx:U13>
         <PDBx:U22>0.8979</PDBx:U22>
         <PDBx:U23>0.0259</PDBx:U23>
         <PDBx:U33>0.7817</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2756">
         <PDBx:U11>0.3019</PDBx:U11>
         <PDBx:U12>0.1336</PDBx:U12>
         <PDBx:U13>-0.0306</PDBx:U13>
         <PDBx:U22>0.9916</PDBx:U22>
         <PDBx:U23>0.0327</PDBx:U23>
         <PDBx:U33>0.8572</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>419</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>119</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2757">
         <PDBx:U11>0.3317</PDBx:U11>
         <PDBx:U12>0.1509</PDBx:U12>
         <PDBx:U13>0.0135</PDBx:U13>
         <PDBx:U22>0.8858</PDBx:U22>
         <PDBx:U23>0.0391</PDBx:U23>
         <PDBx:U33>0.7798</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2758">
         <PDBx:U11>0.3140</PDBx:U11>
         <PDBx:U12>0.1400</PDBx:U12>
         <PDBx:U13>0.0343</PDBx:U13>
         <PDBx:U22>0.8237</PDBx:U22>
         <PDBx:U23>0.0323</PDBx:U23>
         <PDBx:U33>0.7354</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2759">
         <PDBx:U11>0.3387</PDBx:U11>
         <PDBx:U12>0.1350</PDBx:U12>
         <PDBx:U13>0.0299</PDBx:U13>
         <PDBx:U22>0.7987</PDBx:U22>
         <PDBx:U23>0.0359</PDBx:U23>
         <PDBx:U33>0.7041</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2760">
         <PDBx:U11>0.3699</PDBx:U11>
         <PDBx:U12>0.1270</PDBx:U12>
         <PDBx:U13>0.0443</PDBx:U13>
         <PDBx:U22>0.7925</PDBx:U22>
         <PDBx:U23>0.0315</PDBx:U23>
         <PDBx:U33>0.7098</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>420</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>120</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2761">
         <PDBx:U11>0.3279</PDBx:U11>
         <PDBx:U12>0.1398</PDBx:U12>
         <PDBx:U13>0.0104</PDBx:U13>
         <PDBx:U22>0.7900</PDBx:U22>
         <PDBx:U23>0.0442</PDBx:U23>
         <PDBx:U33>0.6741</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2762">
         <PDBx:U11>0.3439</PDBx:U11>
         <PDBx:U12>0.1344</PDBx:U12>
         <PDBx:U13>0.0065</PDBx:U13>
         <PDBx:U22>0.7653</PDBx:U22>
         <PDBx:U23>0.0479</PDBx:U23>
         <PDBx:U33>0.6413</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2763">
         <PDBx:U11>0.3340</PDBx:U11>
         <PDBx:U12>0.1558</PDBx:U12>
         <PDBx:U13>0.0157</PDBx:U13>
         <PDBx:U22>0.7175</PDBx:U22>
         <PDBx:U23>0.0603</PDBx:U23>
         <PDBx:U33>0.6025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2764">
         <PDBx:U11>0.2735</PDBx:U11>
         <PDBx:U12>0.1504</PDBx:U12>
         <PDBx:U13>0.0207</PDBx:U13>
         <PDBx:U22>0.6171</PDBx:U22>
         <PDBx:U23>0.0614</PDBx:U23>
         <PDBx:U33>0.5074</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2765">
         <PDBx:U11>0.3977</PDBx:U11>
         <PDBx:U12>0.1292</PDBx:U12>
         <PDBx:U13>-0.0154</PDBx:U13>
         <PDBx:U22>0.8375</PDBx:U22>
         <PDBx:U23>0.0508</PDBx:U23>
         <PDBx:U33>0.6830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2766">
         <PDBx:U11>0.4187</PDBx:U11>
         <PDBx:U12>0.1198</PDBx:U12>
         <PDBx:U13>-0.0177</PDBx:U13>
         <PDBx:U22>0.8231</PDBx:U22>
         <PDBx:U23>0.0518</PDBx:U23>
         <PDBx:U33>0.6586</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2767">
         <PDBx:U11>0.4691</PDBx:U11>
         <PDBx:U12>0.1147</PDBx:U12>
         <PDBx:U13>-0.0396</PDBx:U13>
         <PDBx:U22>0.8978</PDBx:U22>
         <PDBx:U23>0.0531</PDBx:U23>
         <PDBx:U33>0.6904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2768">
         <PDBx:U11>0.2599</PDBx:U11>
         <PDBx:U12>0.1448</PDBx:U12>
         <PDBx:U13>-0.0474</PDBx:U13>
         <PDBx:U22>0.7055</PDBx:U22>
         <PDBx:U23>0.0746</PDBx:U23>
         <PDBx:U33>0.4814</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>421</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>121</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2769">
         <PDBx:U11>0.3174</PDBx:U11>
         <PDBx:U12>0.1806</PDBx:U12>
         <PDBx:U13>0.0180</PDBx:U13>
         <PDBx:U22>0.7126</PDBx:U22>
         <PDBx:U23>0.0695</PDBx:U23>
         <PDBx:U33>0.6029</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2770">
         <PDBx:U11>0.3680</PDBx:U11>
         <PDBx:U12>0.2030</PDBx:U12>
         <PDBx:U13>0.0270</PDBx:U13>
         <PDBx:U22>0.7223</PDBx:U22>
         <PDBx:U23>0.0816</PDBx:U23>
         <PDBx:U33>0.6289</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2771">
         <PDBx:U11>0.3673</PDBx:U11>
         <PDBx:U12>0.2004</PDBx:U12>
         <PDBx:U13>0.0481</PDBx:U13>
         <PDBx:U22>0.6800</PDBx:U22>
         <PDBx:U23>0.0735</PDBx:U23>
         <PDBx:U33>0.6111</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2772">
         <PDBx:U11>0.3446</PDBx:U11>
         <PDBx:U12>0.2072</PDBx:U12>
         <PDBx:U13>0.0541</PDBx:U13>
         <PDBx:U22>0.6102</PDBx:U22>
         <PDBx:U23>0.0793</PDBx:U23>
         <PDBx:U33>0.5558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2773">
         <PDBx:U11>0.4303</PDBx:U11>
         <PDBx:U12>0.2325</PDBx:U12>
         <PDBx:U13>0.0260</PDBx:U13>
         <PDBx:U22>0.8033</PDBx:U22>
         <PDBx:U23>0.0925</PDBx:U23>
         <PDBx:U33>0.7161</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2774">
         <PDBx:U11>0.4580</PDBx:U11>
         <PDBx:U12>0.2374</PDBx:U12>
         <PDBx:U13>0.0392</PDBx:U13>
         <PDBx:U22>0.8602</PDBx:U22>
         <PDBx:U23>0.0817</PDBx:U23>
         <PDBx:U33>0.7850</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2775">
         <PDBx:U11>0.4811</PDBx:U11>
         <PDBx:U12>0.2549</PDBx:U12>
         <PDBx:U13>0.0343</PDBx:U13>
         <PDBx:U22>0.8023</PDBx:U22>
         <PDBx:U23>0.1055</PDBx:U23>
         <PDBx:U33>0.7387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>422</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>122</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2776">
         <PDBx:U11>0.3135</PDBx:U11>
         <PDBx:U12>0.1900</PDBx:U12>
         <PDBx:U13>0.0598</PDBx:U13>
         <PDBx:U22>0.6430</PDBx:U22>
         <PDBx:U23>0.0600</PDBx:U23>
         <PDBx:U33>0.5788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2777">
         <PDBx:U11>0.3442</PDBx:U11>
         <PDBx:U12>0.1855</PDBx:U12>
         <PDBx:U13>0.0795</PDBx:U13>
         <PDBx:U22>0.6377</PDBx:U22>
         <PDBx:U23>0.0514</PDBx:U23>
         <PDBx:U33>0.5889</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2778">
         <PDBx:U11>0.3365</PDBx:U11>
         <PDBx:U12>0.1672</PDBx:U12>
         <PDBx:U13>0.0756</PDBx:U13>
         <PDBx:U22>0.5956</PDBx:U22>
         <PDBx:U23>0.0500</PDBx:U23>
         <PDBx:U33>0.5443</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2779">
         <PDBx:U11>0.3389</PDBx:U11>
         <PDBx:U12>0.1707</PDBx:U12>
         <PDBx:U13>0.0861</PDBx:U13>
         <PDBx:U22>0.5538</PDBx:U22>
         <PDBx:U23>0.0493</PDBx:U23>
         <PDBx:U33>0.5158</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2780">
         <PDBx:U11>0.4236</PDBx:U11>
         <PDBx:U12>0.1739</PDBx:U12>
         <PDBx:U13>0.0926</PDBx:U13>
         <PDBx:U22>0.7458</PDBx:U22>
         <PDBx:U23>0.0387</PDBx:U23>
         <PDBx:U33>0.6964</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2781">
         <PDBx:U11>0.6187</PDBx:U11>
         <PDBx:U12>0.1950</PDBx:U12>
         <PDBx:U13>0.1068</PDBx:U13>
         <PDBx:U22>0.9632</PDBx:U22>
         <PDBx:U23>0.0373</PDBx:U23>
         <PDBx:U33>0.9215</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2782">
         <PDBx:U11>0.7170</PDBx:U11>
         <PDBx:U12>0.2026</PDBx:U12>
         <PDBx:U13>0.0937</PDBx:U13>
         <PDBx:U22>1.1165</PDBx:U22>
         <PDBx:U23>0.0416</PDBx:U23>
         <PDBx:U33>1.0674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2783">
         <PDBx:U11>0.7575</PDBx:U11>
         <PDBx:U12>0.2009</PDBx:U12>
         <PDBx:U13>0.0722</PDBx:U13>
         <PDBx:U22>1.1665</PDBx:U22>
         <PDBx:U23>0.0497</PDBx:U23>
         <PDBx:U33>1.1061</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2784">
         <PDBx:U11>0.7748</PDBx:U11>
         <PDBx:U12>0.2103</PDBx:U12>
         <PDBx:U13>0.1050</PDBx:U13>
         <PDBx:U22>1.2104</PDBx:U22>
         <PDBx:U23>0.0366</PDBx:U23>
         <PDBx:U33>1.1643</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>423</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>123</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2785">
         <PDBx:U11>0.3201</PDBx:U11>
         <PDBx:U12>0.1480</PDBx:U12>
         <PDBx:U13>0.0605</PDBx:U13>
         <PDBx:U22>0.5991</PDBx:U22>
         <PDBx:U23>0.0482</PDBx:U23>
         <PDBx:U33>0.5320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2786">
         <PDBx:U11>0.2820</PDBx:U11>
         <PDBx:U12>0.1312</PDBx:U12>
         <PDBx:U13>0.0558</PDBx:U13>
         <PDBx:U22>0.5348</PDBx:U22>
         <PDBx:U23>0.0466</PDBx:U23>
         <PDBx:U33>0.4642</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2787">
         <PDBx:U11>0.3002</PDBx:U11>
         <PDBx:U12>0.1426</PDBx:U12>
         <PDBx:U13>0.0496</PDBx:U13>
         <PDBx:U22>0.5261</PDBx:U22>
         <PDBx:U23>0.0594</PDBx:U23>
         <PDBx:U33>0.4553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2788">
         <PDBx:U11>0.3426</PDBx:U11>
         <PDBx:U12>0.1389</PDBx:U12>
         <PDBx:U13>0.0542</PDBx:U13>
         <PDBx:U22>0.5326</PDBx:U22>
         <PDBx:U23>0.0599</PDBx:U23>
         <PDBx:U33>0.4708</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2789">
         <PDBx:U11>0.3077</PDBx:U11>
         <PDBx:U12>0.1093</PDBx:U12>
         <PDBx:U13>0.0422</PDBx:U13>
         <PDBx:U22>0.5866</PDBx:U22>
         <PDBx:U23>0.0395</PDBx:U23>
         <PDBx:U33>0.5020</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2790">
         <PDBx:U11>0.3596</PDBx:U11>
         <PDBx:U12>0.0983</PDBx:U12>
         <PDBx:U13>0.0486</PDBx:U13>
         <PDBx:U22>0.6666</PDBx:U22>
         <PDBx:U23>0.0288</PDBx:U23>
         <PDBx:U33>0.5888</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2791">
         <PDBx:U11>0.2911</PDBx:U11>
         <PDBx:U12>0.0930</PDBx:U12>
         <PDBx:U13>0.0400</PDBx:U13>
         <PDBx:U22>0.5428</PDBx:U22>
         <PDBx:U23>0.0359</PDBx:U23>
         <PDBx:U33>0.4580</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2792">
         <PDBx:U11>0.4180</PDBx:U11>
         <PDBx:U12>0.0897</PDBx:U12>
         <PDBx:U13>0.0670</PDBx:U13>
         <PDBx:U22>0.7041</PDBx:U22>
         <PDBx:U23>0.0217</PDBx:U23>
         <PDBx:U33>0.6395</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>424</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>124</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2793">
         <PDBx:U11>0.3185</PDBx:U11>
         <PDBx:U12>0.1566</PDBx:U12>
         <PDBx:U13>0.0396</PDBx:U13>
         <PDBx:U22>0.5620</PDBx:U22>
         <PDBx:U23>0.0705</PDBx:U23>
         <PDBx:U33>0.4817</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2794">
         <PDBx:U11>0.3096</PDBx:U11>
         <PDBx:U12>0.1682</PDBx:U12>
         <PDBx:U13>0.0354</PDBx:U13>
         <PDBx:U22>0.5268</PDBx:U22>
         <PDBx:U23>0.0856</PDBx:U23>
         <PDBx:U33>0.4489</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2795">
         <PDBx:U11>0.3245</PDBx:U11>
         <PDBx:U12>0.1823</PDBx:U12>
         <PDBx:U13>0.0509</PDBx:U13>
         <PDBx:U22>0.4897</PDBx:U22>
         <PDBx:U23>0.0886</PDBx:U23>
         <PDBx:U33>0.4457</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2796">
         <PDBx:U11>0.2937</PDBx:U11>
         <PDBx:U12>0.1801</PDBx:U12>
         <PDBx:U13>0.0520</PDBx:U13>
         <PDBx:U22>0.4210</PDBx:U22>
         <PDBx:U23>0.0943</PDBx:U23>
         <PDBx:U33>0.3897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2797">
         <PDBx:U11>0.3328</PDBx:U11>
         <PDBx:U12>0.1841</PDBx:U12>
         <PDBx:U13>0.0239</PDBx:U13>
         <PDBx:U22>0.5766</PDBx:U22>
         <PDBx:U23>0.0986</PDBx:U23>
         <PDBx:U33>0.4843</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2798">
         <PDBx:U11>0.3285</PDBx:U11>
         <PDBx:U12>0.1713</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.6055</PDBx:U22>
         <PDBx:U23>0.0996</PDBx:U23>
         <PDBx:U33>0.4774</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2799">
         <PDBx:U11>0.3932</PDBx:U11>
         <PDBx:U12>0.1838</PDBx:U12>
         <PDBx:U13>-0.0044</PDBx:U13>
         <PDBx:U22>0.6816</PDBx:U22>
         <PDBx:U23>0.1153</PDBx:U23>
         <PDBx:U33>0.5352</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2800">
         <PDBx:U11>0.3407</PDBx:U11>
         <PDBx:U12>0.1474</PDBx:U12>
         <PDBx:U13>0.0022</PDBx:U13>
         <PDBx:U22>0.6341</PDBx:U22>
         <PDBx:U23>0.0843</PDBx:U23>
         <PDBx:U33>0.4918</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2801">
         <PDBx:U11>0.4257</PDBx:U11>
         <PDBx:U12>0.1727</PDBx:U12>
         <PDBx:U13>-0.0190</PDBx:U13>
         <PDBx:U22>0.7444</PDBx:U22>
         <PDBx:U23>0.1143</PDBx:U23>
         <PDBx:U33>0.5605</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2802">
         <PDBx:U11>0.3851</PDBx:U11>
         <PDBx:U12>0.1365</PDBx:U12>
         <PDBx:U13>-0.0122</PDBx:U13>
         <PDBx:U22>0.7048</PDBx:U22>
         <PDBx:U23>0.0820</PDBx:U23>
         <PDBx:U33>0.5307</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2803">
         <PDBx:U11>0.4036</PDBx:U11>
         <PDBx:U12>0.1492</PDBx:U12>
         <PDBx:U13>-0.0226</PDBx:U13>
         <PDBx:U22>0.7377</PDBx:U22>
         <PDBx:U23>0.0963</PDBx:U23>
         <PDBx:U33>0.5399</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>425</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>125</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2804">
         <PDBx:U11>0.3764</PDBx:U11>
         <PDBx:U12>0.1960</PDBx:U12>
         <PDBx:U13>0.0632</PDBx:U13>
         <PDBx:U22>0.5384</PDBx:U22>
         <PDBx:U23>0.0831</PDBx:U23>
         <PDBx:U33>0.5110</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2805">
         <PDBx:U11>0.3597</PDBx:U11>
         <PDBx:U12>0.2095</PDBx:U12>
         <PDBx:U13>0.0789</PDBx:U13>
         <PDBx:U22>0.4681</PDBx:U22>
         <PDBx:U23>0.0809</PDBx:U23>
         <PDBx:U33>0.4744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2806">
         <PDBx:U11>0.3495</PDBx:U11>
         <PDBx:U12>0.1935</PDBx:U12>
         <PDBx:U13>0.0868</PDBx:U13>
         <PDBx:U22>0.4229</PDBx:U22>
         <PDBx:U23>0.0698</PDBx:U23>
         <PDBx:U33>0.4368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2807">
         <PDBx:U11>0.4103</PDBx:U11>
         <PDBx:U12>0.1968</PDBx:U12>
         <PDBx:U13>0.0922</PDBx:U13>
         <PDBx:U22>0.4298</PDBx:U22>
         <PDBx:U23>0.0697</PDBx:U23>
         <PDBx:U33>0.4702</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2808">
         <PDBx:U11>0.4107</PDBx:U11>
         <PDBx:U12>0.2261</PDBx:U12>
         <PDBx:U13>0.0920</PDBx:U13>
         <PDBx:U22>0.5293</PDBx:U22>
         <PDBx:U23>0.0737</PDBx:U23>
         <PDBx:U33>0.5457</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2809">
         <PDBx:U11>0.4837</PDBx:U11>
         <PDBx:U12>0.2488</PDBx:U12>
         <PDBx:U13>0.0857</PDBx:U13>
         <PDBx:U22>0.6242</PDBx:U22>
         <PDBx:U23>0.0860</PDBx:U23>
         <PDBx:U33>0.6431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2810">
         <PDBx:U11>0.4628</PDBx:U11>
         <PDBx:U12>0.2572</PDBx:U12>
         <PDBx:U13>0.0764</PDBx:U13>
         <PDBx:U22>0.5841</PDBx:U22>
         <PDBx:U23>0.1011</PDBx:U23>
         <PDBx:U33>0.6106</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2811">
         <PDBx:U11>0.4412</PDBx:U11>
         <PDBx:U12>0.2583</PDBx:U12>
         <PDBx:U13>0.0901</PDBx:U13>
         <PDBx:U22>0.6187</PDBx:U22>
         <PDBx:U23>0.0815</PDBx:U23>
         <PDBx:U33>0.6324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>426</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>126</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2812">
         <PDBx:U11>0.3319</PDBx:U11>
         <PDBx:U12>0.1749</PDBx:U12>
         <PDBx:U13>0.0866</PDBx:U13>
         <PDBx:U22>0.4333</PDBx:U22>
         <PDBx:U23>0.0599</PDBx:U23>
         <PDBx:U33>0.4267</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2813">
         <PDBx:U11>0.3402</PDBx:U11>
         <PDBx:U12>0.1598</PDBx:U12>
         <PDBx:U13>0.0925</PDBx:U13>
         <PDBx:U22>0.4139</PDBx:U22>
         <PDBx:U23>0.0502</PDBx:U23>
         <PDBx:U33>0.4098</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2814">
         <PDBx:U11>0.3461</PDBx:U11>
         <PDBx:U12>0.1501</PDBx:U12>
         <PDBx:U13>0.0817</PDBx:U13>
         <PDBx:U22>0.4051</PDBx:U22>
         <PDBx:U23>0.0569</PDBx:U23>
         <PDBx:U33>0.4004</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2815">
         <PDBx:U11>0.3640</PDBx:U11>
         <PDBx:U12>0.1468</PDBx:U12>
         <PDBx:U13>0.0866</PDBx:U13>
         <PDBx:U22>0.3792</PDBx:U22>
         <PDBx:U23>0.0525</PDBx:U23>
         <PDBx:U33>0.3912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2816">
         <PDBx:U11>0.3176</PDBx:U11>
         <PDBx:U12>0.1420</PDBx:U12>
         <PDBx:U13>0.0944</PDBx:U13>
         <PDBx:U22>0.4241</PDBx:U22>
         <PDBx:U23>0.0405</PDBx:U23>
         <PDBx:U33>0.4008</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2817">
         <PDBx:U11>0.3724</PDBx:U11>
         <PDBx:U12>0.1494</PDBx:U12>
         <PDBx:U13>0.1082</PDBx:U13>
         <PDBx:U22>0.4946</PDBx:U22>
         <PDBx:U23>0.0338</PDBx:U23>
         <PDBx:U33>0.4717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2818">
         <PDBx:U11>0.4824</PDBx:U11>
         <PDBx:U12>0.1259</PDBx:U12>
         <PDBx:U13>0.1135</PDBx:U13>
         <PDBx:U22>0.6313</PDBx:U22>
         <PDBx:U23>0.0244</PDBx:U23>
         <PDBx:U33>0.5925</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2819">
         <PDBx:U11>1.0847</PDBx:U11>
         <PDBx:U12>0.1391</PDBx:U12>
         <PDBx:U13>0.1308</PDBx:U13>
         <PDBx:U22>1.2599</PDBx:U22>
         <PDBx:U23>0.0198</PDBx:U23>
         <PDBx:U33>1.2210</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>427</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>127</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2820">
         <PDBx:U11>0.2971</PDBx:U11>
         <PDBx:U12>0.1449</PDBx:U12>
         <PDBx:U13>0.0667</PDBx:U13>
         <PDBx:U22>0.3923</PDBx:U22>
         <PDBx:U23>0.0661</PDBx:U23>
         <PDBx:U33>0.3672</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2821">
         <PDBx:U11>0.2656</PDBx:U11>
         <PDBx:U12>0.1360</PDBx:U12>
         <PDBx:U13>0.0565</PDBx:U13>
         <PDBx:U22>0.3550</PDBx:U22>
         <PDBx:U23>0.0739</PDBx:U23>
         <PDBx:U33>0.3240</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2822">
         <PDBx:U11>0.3236</PDBx:U11>
         <PDBx:U12>0.1480</PDBx:U12>
         <PDBx:U13>0.0585</PDBx:U13>
         <PDBx:U22>0.3647</PDBx:U22>
         <PDBx:U23>0.0865</PDBx:U23>
         <PDBx:U33>0.3631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2823">
         <PDBx:U11>0.3467</PDBx:U11>
         <PDBx:U12>0.1370</PDBx:U12>
         <PDBx:U13>0.0566</PDBx:U13>
         <PDBx:U22>0.3534</PDBx:U22>
         <PDBx:U23>0.0884</PDBx:U23>
         <PDBx:U33>0.3666</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2824">
         <PDBx:U11>0.2295</PDBx:U11>
         <PDBx:U12>0.1273</PDBx:U12>
         <PDBx:U13>0.0410</PDBx:U13>
         <PDBx:U22>0.3665</PDBx:U22>
         <PDBx:U23>0.0780</PDBx:U23>
         <PDBx:U33>0.3025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2825">
         <PDBx:U11>0.2260</PDBx:U11>
         <PDBx:U12>0.1084</PDBx:U12>
         <PDBx:U13>0.0361</PDBx:U13>
         <PDBx:U22>0.3959</PDBx:U22>
         <PDBx:U23>0.0632</PDBx:U23>
         <PDBx:U33>0.3135</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2826">
         <PDBx:U11>0.2000</PDBx:U11>
         <PDBx:U12>0.1045</PDBx:U12>
         <PDBx:U13>0.0224</PDBx:U13>
         <PDBx:U22>0.4083</PDBx:U22>
         <PDBx:U23>0.0635</PDBx:U23>
         <PDBx:U33>0.3002</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2827">
         <PDBx:U11>0.1501</PDBx:U11>
         <PDBx:U12>0.0906</PDBx:U12>
         <PDBx:U13>0.0350</PDBx:U13>
         <PDBx:U22>0.3094</PDBx:U22>
         <PDBx:U23>0.0560</PDBx:U23>
         <PDBx:U33>0.2259</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>428</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>128</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2828">
         <PDBx:U11>0.3015</PDBx:U11>
         <PDBx:U12>0.1653</PDBx:U12>
         <PDBx:U13>0.0605</PDBx:U13>
         <PDBx:U22>0.3365</PDBx:U22>
         <PDBx:U23>0.0941</PDBx:U23>
         <PDBx:U33>0.3463</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2829">
         <PDBx:U11>0.3639</PDBx:U11>
         <PDBx:U12>0.1744</PDBx:U12>
         <PDBx:U13>0.0631</PDBx:U13>
         <PDBx:U22>0.3458</PDBx:U22>
         <PDBx:U23>0.1049</PDBx:U23>
         <PDBx:U33>0.3912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2830">
         <PDBx:U11>0.4322</PDBx:U11>
         <PDBx:U12>0.1715</PDBx:U12>
         <PDBx:U13>0.0749</PDBx:U13>
         <PDBx:U22>0.3507</PDBx:U22>
         <PDBx:U23>0.0916</PDBx:U23>
         <PDBx:U33>0.4355</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2831">
         <PDBx:U11>0.5026</PDBx:U11>
         <PDBx:U12>0.1615</PDBx:U12>
         <PDBx:U13>0.0733</PDBx:U13>
         <PDBx:U22>0.3715</PDBx:U22>
         <PDBx:U23>0.0952</PDBx:U23>
         <PDBx:U33>0.4855</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2832">
         <PDBx:U11>0.3811</PDBx:U11>
         <PDBx:U12>0.1963</PDBx:U12>
         <PDBx:U13>0.0639</PDBx:U13>
         <PDBx:U22>0.3697</PDBx:U22>
         <PDBx:U23>0.1137</PDBx:U23>
         <PDBx:U33>0.4218</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2833">
         <PDBx:U11>0.4050</PDBx:U11>
         <PDBx:U12>0.2002</PDBx:U12>
         <PDBx:U13>0.0499</PDBx:U13>
         <PDBx:U22>0.4419</PDBx:U22>
         <PDBx:U23>0.1289</PDBx:U23>
         <PDBx:U33>0.4602</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2834">
         <PDBx:U11>0.3945</PDBx:U11>
         <PDBx:U12>0.2247</PDBx:U12>
         <PDBx:U13>0.0508</PDBx:U13>
         <PDBx:U22>0.4390</PDBx:U22>
         <PDBx:U23>0.1363</PDBx:U23>
         <PDBx:U33>0.4659</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2835">
         <PDBx:U11>0.3850</PDBx:U11>
         <PDBx:U12>0.1907</PDBx:U12>
         <PDBx:U13>0.0423</PDBx:U13>
         <PDBx:U22>0.4041</PDBx:U22>
         <PDBx:U23>0.1449</PDBx:U23>
         <PDBx:U33>0.4215</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>429</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>129</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2836">
         <PDBx:U11>0.4288</PDBx:U11>
         <PDBx:U12>0.1764</PDBx:U12>
         <PDBx:U13>0.0861</PDBx:U13>
         <PDBx:U22>0.3493</PDBx:U22>
         <PDBx:U23>0.0746</PDBx:U23>
         <PDBx:U33>0.4325</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2837">
         <PDBx:U11>0.5185</PDBx:U11>
         <PDBx:U12>0.1724</PDBx:U12>
         <PDBx:U13>0.0968</PDBx:U13>
         <PDBx:U22>0.3819</PDBx:U22>
         <PDBx:U23>0.0568</PDBx:U23>
         <PDBx:U33>0.4926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2838">
         <PDBx:U11>0.4727</PDBx:U11>
         <PDBx:U12>0.1490</PDBx:U12>
         <PDBx:U13>0.0907</PDBx:U13>
         <PDBx:U22>0.3149</PDBx:U22>
         <PDBx:U23>0.0505</PDBx:U23>
         <PDBx:U33>0.4253</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2839">
         <PDBx:U11>0.4957</PDBx:U11>
         <PDBx:U12>0.1362</PDBx:U12>
         <PDBx:U13>0.0897</PDBx:U13>
         <PDBx:U22>0.2821</PDBx:U22>
         <PDBx:U23>0.0409</PDBx:U23>
         <PDBx:U33>0.4205</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2840">
         <PDBx:U11>0.5384</PDBx:U11>
         <PDBx:U12>0.1794</PDBx:U12>
         <PDBx:U13>0.1098</PDBx:U13>
         <PDBx:U22>0.4196</PDBx:U22>
         <PDBx:U23>0.0413</PDBx:U23>
         <PDBx:U33>0.5153</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>430</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>130</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2841">
         <PDBx:U11>0.4138</PDBx:U11>
         <PDBx:U12>0.1337</PDBx:U12>
         <PDBx:U13>0.0813</PDBx:U13>
         <PDBx:U22>0.3094</PDBx:U22>
         <PDBx:U23>0.0525</PDBx:U23>
         <PDBx:U33>0.3817</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2842">
         <PDBx:U11>0.3965</PDBx:U11>
         <PDBx:U12>0.1042</PDBx:U12>
         <PDBx:U13>0.0699</PDBx:U13>
         <PDBx:U22>0.2900</PDBx:U22>
         <PDBx:U23>0.0457</PDBx:U23>
         <PDBx:U33>0.3506</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2843">
         <PDBx:U11>0.4383</PDBx:U11>
         <PDBx:U12>0.0908</PDBx:U12>
         <PDBx:U13>0.0594</PDBx:U13>
         <PDBx:U22>0.3114</PDBx:U22>
         <PDBx:U23>0.0575</PDBx:U23>
         <PDBx:U33>0.3884</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2844">
         <PDBx:U11>0.4149</PDBx:U11>
         <PDBx:U12>0.0701</PDBx:U12>
         <PDBx:U13>0.0536</PDBx:U13>
         <PDBx:U22>0.2578</PDBx:U22>
         <PDBx:U23>0.0499</PDBx:U23>
         <PDBx:U33>0.3478</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2845">
         <PDBx:U11>0.3511</PDBx:U11>
         <PDBx:U12>0.0943</PDBx:U12>
         <PDBx:U13>0.0639</PDBx:U13>
         <PDBx:U22>0.3034</PDBx:U22>
         <PDBx:U23>0.0456</PDBx:U23>
         <PDBx:U33>0.3255</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2846">
         <PDBx:U11>0.4000</PDBx:U11>
         <PDBx:U12>0.1031</PDBx:U12>
         <PDBx:U13>0.0759</PDBx:U13>
         <PDBx:U22>0.3705</PDBx:U22>
         <PDBx:U23>0.0368</PDBx:U23>
         <PDBx:U33>0.3802</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2847">
         <PDBx:U11>0.3374</PDBx:U11>
         <PDBx:U12>0.0685</PDBx:U12>
         <PDBx:U13>0.0528</PDBx:U13>
         <PDBx:U22>0.2863</PDBx:U22>
         <PDBx:U23>0.0394</PDBx:U23>
         <PDBx:U33>0.2999</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>431</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>131</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2848">
         <PDBx:U11>0.4153</PDBx:U11>
         <PDBx:U12>0.1022</PDBx:U12>
         <PDBx:U13>0.0568</PDBx:U13>
         <PDBx:U22>0.3083</PDBx:U22>
         <PDBx:U23>0.0772</PDBx:U23>
         <PDBx:U33>0.3818</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2849">
         <PDBx:U11>0.4207</PDBx:U11>
         <PDBx:U12>0.0909</PDBx:U12>
         <PDBx:U13>0.0507</PDBx:U13>
         <PDBx:U22>0.2961</PDBx:U22>
         <PDBx:U23>0.0932</PDBx:U23>
         <PDBx:U33>0.3828</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2850">
         <PDBx:U11>0.5106</PDBx:U11>
         <PDBx:U12>0.0897</PDBx:U12>
         <PDBx:U13>0.0565</PDBx:U13>
         <PDBx:U22>0.3134</PDBx:U22>
         <PDBx:U23>0.0922</PDBx:U23>
         <PDBx:U33>0.4536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2851">
         <PDBx:U11>0.5546</PDBx:U11>
         <PDBx:U12>0.0671</PDBx:U12>
         <PDBx:U13>0.0521</PDBx:U13>
         <PDBx:U22>0.3303</PDBx:U22>
         <PDBx:U23>0.0945</PDBx:U23>
         <PDBx:U33>0.4897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2852">
         <PDBx:U11>0.4862</PDBx:U11>
         <PDBx:U12>0.1076</PDBx:U12>
         <PDBx:U13>0.0477</PDBx:U13>
         <PDBx:U22>0.3962</PDBx:U22>
         <PDBx:U23>0.1166</PDBx:U23>
         <PDBx:U33>0.4629</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2853">
         <PDBx:U11>0.5430</PDBx:U11>
         <PDBx:U12>0.0951</PDBx:U12>
         <PDBx:U13>0.0441</PDBx:U13>
         <PDBx:U22>0.4400</PDBx:U22>
         <PDBx:U23>0.1342</PDBx:U23>
         <PDBx:U33>0.5127</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>432</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>132</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2854">
         <PDBx:U11>0.5015</PDBx:U11>
         <PDBx:U12>0.1138</PDBx:U12>
         <PDBx:U13>0.0673</PDBx:U13>
         <PDBx:U22>0.2736</PDBx:U22>
         <PDBx:U23>0.0875</PDBx:U23>
         <PDBx:U33>0.4396</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2855">
         <PDBx:U11>0.6572</PDBx:U11>
         <PDBx:U12>0.1118</PDBx:U12>
         <PDBx:U13>0.0720</PDBx:U13>
         <PDBx:U22>0.3624</PDBx:U22>
         <PDBx:U23>0.0790</PDBx:U23>
         <PDBx:U33>0.5778</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2856">
         <PDBx:U11>0.6583</PDBx:U11>
         <PDBx:U12>0.0887</PDBx:U12>
         <PDBx:U13>0.0706</PDBx:U13>
         <PDBx:U22>0.3230</PDBx:U22>
         <PDBx:U23>0.0555</PDBx:U23>
         <PDBx:U33>0.5535</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2857">
         <PDBx:U11>0.6724</PDBx:U11>
         <PDBx:U12>0.0699</PDBx:U12>
         <PDBx:U13>0.0665</PDBx:U13>
         <PDBx:U22>0.2913</PDBx:U22>
         <PDBx:U23>0.0499</PDBx:U23>
         <PDBx:U33>0.5568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2858">
         <PDBx:U11>0.7272</PDBx:U11>
         <PDBx:U12>0.1399</PDBx:U12>
         <PDBx:U13>0.0825</PDBx:U13>
         <PDBx:U22>0.4262</PDBx:U22>
         <PDBx:U23>0.0721</PDBx:U23>
         <PDBx:U33>0.6517</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2859">
         <PDBx:U11>0.8695</PDBx:U11>
         <PDBx:U12>0.1373</PDBx:U12>
         <PDBx:U13>0.0868</PDBx:U13>
         <PDBx:U22>0.5048</PDBx:U22>
         <PDBx:U23>0.0584</PDBx:U23>
         <PDBx:U33>0.7759</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>433</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>133</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2860">
         <PDBx:U11>0.5784</PDBx:U11>
         <PDBx:U12>0.0846</PDBx:U12>
         <PDBx:U13>0.0692</PDBx:U13>
         <PDBx:U22>0.2779</PDBx:U22>
         <PDBx:U23>0.0392</PDBx:U23>
         <PDBx:U33>0.4698</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2861">
         <PDBx:U11>0.5687</PDBx:U11>
         <PDBx:U12>0.0616</PDBx:U12>
         <PDBx:U13>0.0628</PDBx:U13>
         <PDBx:U22>0.2475</PDBx:U22>
         <PDBx:U23>0.0161</PDBx:U23>
         <PDBx:U33>0.4355</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2862">
         <PDBx:U11>0.5724</PDBx:U11>
         <PDBx:U12>0.0300</PDBx:U12>
         <PDBx:U13>0.0468</PDBx:U13>
         <PDBx:U22>0.2629</PDBx:U22>
         <PDBx:U23>0.0214</PDBx:U23>
         <PDBx:U33>0.4468</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2863">
         <PDBx:U11>0.5871</PDBx:U11>
         <PDBx:U12>0.0083</PDBx:U12>
         <PDBx:U13>0.0393</PDBx:U13>
         <PDBx:U22>0.2396</PDBx:U22>
         <PDBx:U23>0.0087</PDBx:U23>
         <PDBx:U33>0.4460</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2864">
         <PDBx:U11>0.5803</PDBx:U11>
         <PDBx:U12>0.0665</PDBx:U12>
         <PDBx:U13>0.0658</PDBx:U13>
         <PDBx:U22>0.2976</PDBx:U22>
         <PDBx:U23>0.0036</PDBx:U23>
         <PDBx:U33>0.4415</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2865">
         <PDBx:U11>0.6720</PDBx:U11>
         <PDBx:U12>0.0457</PDBx:U12>
         <PDBx:U13>0.0572</PDBx:U13>
         <PDBx:U22>0.3732</PDBx:U22>
         <PDBx:U23>-0.0173</PDBx:U23>
         <PDBx:U33>0.5032</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2866">
         <PDBx:U11>0.7778</PDBx:U11>
         <PDBx:U12>0.0455</PDBx:U12>
         <PDBx:U13>0.0614</PDBx:U13>
         <PDBx:U22>0.4101</PDBx:U22>
         <PDBx:U23>-0.0382</PDBx:U23>
         <PDBx:U33>0.5735</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2867">
         <PDBx:U11>0.8265</PDBx:U11>
         <PDBx:U12>0.0266</PDBx:U12>
         <PDBx:U13>0.0505</PDBx:U13>
         <PDBx:U22>0.4482</PDBx:U22>
         <PDBx:U23>-0.0594</PDBx:U23>
         <PDBx:U33>0.5886</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2868">
         <PDBx:U11>0.9863</PDBx:U11>
         <PDBx:U12>0.0096</PDBx:U12>
         <PDBx:U13>0.0412</PDBx:U13>
         <PDBx:U22>0.5605</PDBx:U22>
         <PDBx:U23>-0.0781</PDBx:U23>
         <PDBx:U33>0.7229</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2869">
         <PDBx:U11>0.9765</PDBx:U11>
         <PDBx:U12>0.0077</PDBx:U12>
         <PDBx:U13>0.0425</PDBx:U13>
         <PDBx:U22>0.5159</PDBx:U22>
         <PDBx:U23>-0.0762</PDBx:U23>
         <PDBx:U33>0.7256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2870">
         <PDBx:U11>1.0519</PDBx:U11>
         <PDBx:U12>-0.0060</PDBx:U12>
         <PDBx:U13>0.0279</PDBx:U13>
         <PDBx:U22>0.6323</PDBx:U22>
         <PDBx:U23>-0.0947</PDBx:U23>
         <PDBx:U33>0.7619</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>434</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>134</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2871">
         <PDBx:U11>0.4778</PDBx:U11>
         <PDBx:U12>0.0272</PDBx:U12>
         <PDBx:U13>0.0418</PDBx:U13>
         <PDBx:U22>0.2234</PDBx:U22>
         <PDBx:U23>0.0386</PDBx:U23>
         <PDBx:U33>0.3775</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2872">
         <PDBx:U11>0.4969</PDBx:U11>
         <PDBx:U12>0.0008</PDBx:U12>
         <PDBx:U13>0.0301</PDBx:U13>
         <PDBx:U22>0.2620</PDBx:U22>
         <PDBx:U23>0.0454</PDBx:U23>
         <PDBx:U33>0.4091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2873">
         <PDBx:U11>0.5255</PDBx:U11>
         <PDBx:U12>-0.0118</PDBx:U12>
         <PDBx:U13>0.0311</PDBx:U13>
         <PDBx:U22>0.2477</PDBx:U22>
         <PDBx:U23>0.0571</PDBx:U23>
         <PDBx:U33>0.4388</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2874">
         <PDBx:U11>0.5680</PDBx:U11>
         <PDBx:U12>-0.0393</PDBx:U12>
         <PDBx:U13>0.0226</PDBx:U13>
         <PDBx:U22>0.2803</PDBx:U22>
         <PDBx:U23>0.0526</PDBx:U23>
         <PDBx:U33>0.4842</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2875">
         <PDBx:U11>0.4413</PDBx:U11>
         <PDBx:U12>0.0047</PDBx:U12>
         <PDBx:U13>0.0281</PDBx:U13>
         <PDBx:U22>0.2704</PDBx:U22>
         <PDBx:U23>0.0602</PDBx:U23>
         <PDBx:U33>0.3771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2876">
         <PDBx:U11>0.4084</PDBx:U11>
         <PDBx:U12>0.0033</PDBx:U12>
         <PDBx:U13>0.0230</PDBx:U13>
         <PDBx:U22>0.2786</PDBx:U22>
         <PDBx:U23>0.0483</PDBx:U23>
         <PDBx:U33>0.3480</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2877">
         <PDBx:U11>0.4293</PDBx:U11>
         <PDBx:U12>-0.0042</PDBx:U12>
         <PDBx:U13>0.0187</PDBx:U13>
         <PDBx:U22>0.2829</PDBx:U22>
         <PDBx:U23>0.0300</PDBx:U23>
         <PDBx:U33>0.3509</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2878">
         <PDBx:U11>0.4714</PDBx:U11>
         <PDBx:U12>0.0094</PDBx:U12>
         <PDBx:U13>0.0223</PDBx:U13>
         <PDBx:U22>0.3939</PDBx:U22>
         <PDBx:U23>0.0557</PDBx:U23>
         <PDBx:U33>0.4300</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2879">
         <PDBx:U11>0.4456</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>0.0150</PDBx:U13>
         <PDBx:U22>0.3320</PDBx:U22>
         <PDBx:U23>0.0233</PDBx:U23>
         <PDBx:U33>0.3691</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2880">
         <PDBx:U11>0.4000</PDBx:U11>
         <PDBx:U12>0.0074</PDBx:U12>
         <PDBx:U13>0.0187</PDBx:U13>
         <PDBx:U22>0.3524</PDBx:U22>
         <PDBx:U23>0.0457</PDBx:U23>
         <PDBx:U33>0.3632</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2881">
         <PDBx:U11>0.3623</PDBx:U11>
         <PDBx:U12>0.0010</PDBx:U12>
         <PDBx:U13>0.0157</PDBx:U13>
         <PDBx:U22>0.2956</PDBx:U22>
         <PDBx:U23>0.0316</PDBx:U23>
         <PDBx:U33>0.3085</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>435</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>135</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2882">
         <PDBx:U11>0.4868</PDBx:U11>
         <PDBx:U12>0.0081</PDBx:U12>
         <PDBx:U13>0.0414</PDBx:U13>
         <PDBx:U22>0.1847</PDBx:U22>
         <PDBx:U23>0.0736</PDBx:U23>
         <PDBx:U33>0.4006</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2883">
         <PDBx:U11>0.6019</PDBx:U11>
         <PDBx:U12>-0.0021</PDBx:U12>
         <PDBx:U13>0.0448</PDBx:U13>
         <PDBx:U22>0.2531</PDBx:U22>
         <PDBx:U23>0.0895</PDBx:U23>
         <PDBx:U33>0.5163</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2884">
         <PDBx:U11>0.6977</PDBx:U11>
         <PDBx:U12>-0.0172</PDBx:U12>
         <PDBx:U13>0.0413</PDBx:U13>
         <PDBx:U22>0.2917</PDBx:U22>
         <PDBx:U23>0.0667</PDBx:U23>
         <PDBx:U33>0.5994</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2885">
         <PDBx:U11>0.6975</PDBx:U11>
         <PDBx:U12>-0.0432</PDBx:U12>
         <PDBx:U13>0.0357</PDBx:U13>
         <PDBx:U22>0.2753</PDBx:U22>
         <PDBx:U23>0.0687</PDBx:U23>
         <PDBx:U33>0.6100</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2886">
         <PDBx:U11>0.6590</PDBx:U11>
         <PDBx:U12>0.0260</PDBx:U12>
         <PDBx:U13>0.0507</PDBx:U13>
         <PDBx:U22>0.3134</PDBx:U22>
         <PDBx:U23>0.1096</PDBx:U23>
         <PDBx:U33>0.5805</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2887">
         <PDBx:U11>0.7822</PDBx:U11>
         <PDBx:U12>0.0157</PDBx:U12>
         <PDBx:U13>0.0496</PDBx:U13>
         <PDBx:U22>0.4043</PDBx:U22>
         <PDBx:U23>0.1265</PDBx:U23>
         <PDBx:U33>0.7080</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2888">
         <PDBx:U11>0.8268</PDBx:U11>
         <PDBx:U12>0.0423</PDBx:U12>
         <PDBx:U13>0.0525</PDBx:U13>
         <PDBx:U22>0.4613</PDBx:U22>
         <PDBx:U23>0.1496</PDBx:U23>
         <PDBx:U33>0.7554</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2889">
         <PDBx:U11>0.8450</PDBx:U11>
         <PDBx:U12>0.0744</PDBx:U12>
         <PDBx:U13>0.0580</PDBx:U13>
         <PDBx:U22>0.4728</PDBx:U22>
         <PDBx:U23>0.1405</PDBx:U23>
         <PDBx:U33>0.7721</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2890">
         <PDBx:U11>0.8182</PDBx:U11>
         <PDBx:U12>0.0966</PDBx:U12>
         <PDBx:U13>0.0591</PDBx:U13>
         <PDBx:U22>0.4969</PDBx:U22>
         <PDBx:U23>0.1409</PDBx:U23>
         <PDBx:U33>0.7530</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2891">
         <PDBx:U11>0.8906</PDBx:U11>
         <PDBx:U12>0.1236</PDBx:U12>
         <PDBx:U13>0.0653</PDBx:U13>
         <PDBx:U22>0.5658</PDBx:U22>
         <PDBx:U23>0.1326</PDBx:U23>
         <PDBx:U33>0.8283</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2892">
         <PDBx:U11>0.7222</PDBx:U11>
         <PDBx:U12>0.0908</PDBx:U12>
         <PDBx:U13>0.0541</PDBx:U13>
         <PDBx:U22>0.4585</PDBx:U22>
         <PDBx:U23>0.1484</PDBx:U23>
         <PDBx:U33>0.6645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>436</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>136</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2893">
         <PDBx:U11>0.7228</PDBx:U11>
         <PDBx:U12>-0.0005</PDBx:U12>
         <PDBx:U13>0.0454</PDBx:U13>
         <PDBx:U22>0.2926</PDBx:U22>
         <PDBx:U23>0.0444</PDBx:U23>
         <PDBx:U33>0.6043</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2894">
         <PDBx:U11>0.7949</PDBx:U11>
         <PDBx:U12>-0.0124</PDBx:U12>
         <PDBx:U13>0.0418</PDBx:U13>
         <PDBx:U22>0.3171</PDBx:U22>
         <PDBx:U23>0.0175</PDBx:U23>
         <PDBx:U33>0.6593</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2895">
         <PDBx:U11>0.7719</PDBx:U11>
         <PDBx:U12>-0.0478</PDBx:U12>
         <PDBx:U13>0.0264</PDBx:U13>
         <PDBx:U22>0.3036</PDBx:U22>
         <PDBx:U23>0.0026</PDBx:U23>
         <PDBx:U33>0.6344</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2896">
         <PDBx:U11>0.7612</PDBx:U11>
         <PDBx:U12>-0.0713</PDBx:U12>
         <PDBx:U13>0.0191</PDBx:U13>
         <PDBx:U22>0.2710</PDBx:U22>
         <PDBx:U23>-0.0030</PDBx:U23>
         <PDBx:U33>0.6335</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2897">
         <PDBx:U11>0.8465</PDBx:U11>
         <PDBx:U12>0.0120</PDBx:U12>
         <PDBx:U13>0.0503</PDBx:U13>
         <PDBx:U22>0.3575</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.6859</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2898">
         <PDBx:U11>0.9534</PDBx:U11>
         <PDBx:U12>0.0426</PDBx:U12>
         <PDBx:U13>0.0636</PDBx:U13>
         <PDBx:U22>0.4400</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.7960</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2899">
         <PDBx:U11>1.5332</PDBx:U11>
         <PDBx:U12>0.0658</PDBx:U12>
         <PDBx:U13>0.0755</PDBx:U13>
         <PDBx:U22>1.0020</PDBx:U22>
         <PDBx:U23>-0.0302</PDBx:U23>
         <PDBx:U33>1.3486</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2900">
         <PDBx:U11>1.0355</PDBx:U11>
         <PDBx:U12>0.0950</PDBx:U12>
         <PDBx:U13>0.0870</PDBx:U13>
         <PDBx:U22>0.5671</PDBx:U22>
         <PDBx:U23>-0.0177</PDBx:U23>
         <PDBx:U33>0.8631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>437</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>137</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2901">
         <PDBx:U11>0.6664</PDBx:U11>
         <PDBx:U12>-0.0506</PDBx:U12>
         <PDBx:U13>0.0205</PDBx:U13>
         <PDBx:U22>0.2348</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.5200</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.6622</PDBx:U11>
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         <PDBx:U13>0.0023</PDBx:U13>
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         <PDBx:U23>-0.0166</PDBx:U23>
         <PDBx:U33>0.5159</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.6509</PDBx:U11>
         <PDBx:U12>-0.1049</PDBx:U12>
         <PDBx:U13>-0.0045</PDBx:U13>
         <PDBx:U22>0.2732</PDBx:U22>
         <PDBx:U23>0.0022</PDBx:U23>
         <PDBx:U33>0.5411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.6217</PDBx:U11>
         <PDBx:U12>-0.1291</PDBx:U12>
         <PDBx:U13>-0.0196</PDBx:U13>
         <PDBx:U22>0.2712</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.5248</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.6654</PDBx:U11>
         <PDBx:U12>-0.0691</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.3122</PDBx:U22>
         <PDBx:U23>-0.0208</PDBx:U23>
         <PDBx:U33>0.5154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.7344</PDBx:U11>
         <PDBx:U12>-0.0450</PDBx:U12>
         <PDBx:U13>0.0076</PDBx:U13>
         <PDBx:U22>0.3636</PDBx:U22>
         <PDBx:U23>-0.0371</PDBx:U23>
         <PDBx:U33>0.5514</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.6570</PDBx:U11>
         <PDBx:U12>-0.0382</PDBx:U12>
         <PDBx:U13>0.0025</PDBx:U13>
         <PDBx:U22>0.3492</PDBx:U22>
         <PDBx:U23>-0.0383</PDBx:U23>
         <PDBx:U33>0.4718</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
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         <PDBx:U11>0.6852</PDBx:U11>
         <PDBx:U12>-0.0708</PDBx:U12>
         <PDBx:U13>-0.0239</PDBx:U13>
         <PDBx:U22>0.3896</PDBx:U22>
         <PDBx:U23>-0.0499</PDBx:U23>
         <PDBx:U33>0.4966</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>438</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>138</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2909">
         <PDBx:U11>0.6346</PDBx:U11>
         <PDBx:U12>-0.0960</PDBx:U12>
         <PDBx:U13>0.0077</PDBx:U13>
         <PDBx:U22>0.2599</PDBx:U22>
         <PDBx:U23>0.0289</PDBx:U23>
         <PDBx:U33>0.5430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2910">
         <PDBx:U11>0.6015</PDBx:U11>
         <PDBx:U12>-0.1147</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.2649</PDBx:U22>
         <PDBx:U23>0.0503</PDBx:U23>
         <PDBx:U33>0.5431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2911">
         <PDBx:U11>0.5199</PDBx:U11>
         <PDBx:U12>-0.1240</PDBx:U12>
         <PDBx:U13>-0.0040</PDBx:U13>
         <PDBx:U22>0.2493</PDBx:U22>
         <PDBx:U23>0.0484</PDBx:U23>
         <PDBx:U33>0.4759</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2912">
         <PDBx:U11>0.4847</PDBx:U11>
         <PDBx:U12>-0.1482</PDBx:U12>
         <PDBx:U13>-0.0140</PDBx:U13>
         <PDBx:U22>0.2409</PDBx:U22>
         <PDBx:U23>0.0440</PDBx:U23>
         <PDBx:U33>0.4626</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2913">
         <PDBx:U11>0.7595</PDBx:U11>
         <PDBx:U12>-0.1397</PDBx:U12>
         <PDBx:U13>0.0040</PDBx:U13>
         <PDBx:U22>0.4017</PDBx:U22>
         <PDBx:U23>0.0453</PDBx:U23>
         <PDBx:U33>0.7207</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2914">
         <PDBx:U11>0.8116</PDBx:U11>
         <PDBx:U12>-0.1542</PDBx:U12>
         <PDBx:U13>0.0117</PDBx:U13>
         <PDBx:U22>0.4879</PDBx:U22>
         <PDBx:U23>0.0696</PDBx:U23>
         <PDBx:U33>0.8067</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2915">
         <PDBx:U11>0.7914</PDBx:U11>
         <PDBx:U12>-0.1419</PDBx:U12>
         <PDBx:U13>0.0210</PDBx:U13>
         <PDBx:U22>0.5002</PDBx:U22>
         <PDBx:U23>0.0919</PDBx:U23>
         <PDBx:U33>0.7903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2916">
         <PDBx:U11>0.8443</PDBx:U11>
         <PDBx:U12>-0.1798</PDBx:U12>
         <PDBx:U13>0.0098</PDBx:U13>
         <PDBx:U22>0.5141</PDBx:U22>
         <PDBx:U23>0.0639</PDBx:U23>
         <PDBx:U33>0.8619</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>439</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>139</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2917">
         <PDBx:U11>0.4280</PDBx:U11>
         <PDBx:U12>-0.0987</PDBx:U12>
         <PDBx:U13>-0.0009</PDBx:U13>
         <PDBx:U22>0.1951</PDBx:U22>
         <PDBx:U23>0.0498</PDBx:U23>
         <PDBx:U33>0.3801</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2918">
         <PDBx:U11>0.4155</PDBx:U11>
         <PDBx:U12>-0.1001</PDBx:U12>
         <PDBx:U13>-0.0090</PDBx:U13>
         <PDBx:U22>0.2458</PDBx:U22>
         <PDBx:U23>0.0474</PDBx:U23>
         <PDBx:U33>0.3837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2919">
         <PDBx:U11>0.4146</PDBx:U11>
         <PDBx:U12>-0.1150</PDBx:U12>
         <PDBx:U13>-0.0072</PDBx:U13>
         <PDBx:U22>0.2865</PDBx:U22>
         <PDBx:U23>0.0651</PDBx:U23>
         <PDBx:U33>0.4143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2920">
         <PDBx:U11>0.4284</PDBx:U11>
         <PDBx:U12>-0.1102</PDBx:U12>
         <PDBx:U13>0.0049</PDBx:U13>
         <PDBx:U22>0.2998</PDBx:U22>
         <PDBx:U23>0.0857</PDBx:U23>
         <PDBx:U33>0.4331</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2921">
         <PDBx:U11>0.3880</PDBx:U11>
         <PDBx:U12>-0.0720</PDBx:U12>
         <PDBx:U13>-0.0027</PDBx:U13>
         <PDBx:U22>0.2453</PDBx:U22>
         <PDBx:U23>0.0488</PDBx:U23>
         <PDBx:U33>0.3498</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2922">
         <PDBx:U11>0.3851</PDBx:U11>
         <PDBx:U12>-0.0703</PDBx:U12>
         <PDBx:U13>-0.0094</PDBx:U13>
         <PDBx:U22>0.2983</PDBx:U22>
         <PDBx:U23>0.0454</PDBx:U23>
         <PDBx:U33>0.3613</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2923">
         <PDBx:U11>0.3937</PDBx:U11>
         <PDBx:U12>-0.0779</PDBx:U12>
         <PDBx:U13>-0.0225</PDBx:U13>
         <PDBx:U22>0.3021</PDBx:U22>
         <PDBx:U23>0.0269</PDBx:U23>
         <PDBx:U33>0.3576</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2924">
         <PDBx:U11>0.3413</PDBx:U11>
         <PDBx:U12>-0.0467</PDBx:U12>
         <PDBx:U13>-0.0012</PDBx:U13>
         <PDBx:U22>0.2794</PDBx:U22>
         <PDBx:U23>0.0496</PDBx:U23>
         <PDBx:U33>0.3172</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>440</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>140</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2925">
         <PDBx:U11>0.3354</PDBx:U11>
         <PDBx:U12>-0.1313</PDBx:U12>
         <PDBx:U13>-0.0186</PDBx:U13>
         <PDBx:U22>0.2456</PDBx:U22>
         <PDBx:U23>0.0580</PDBx:U23>
         <PDBx:U33>0.3556</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2926">
         <PDBx:U11>0.3499</PDBx:U11>
         <PDBx:U12>-0.1438</PDBx:U12>
         <PDBx:U13>-0.0146</PDBx:U13>
         <PDBx:U22>0.3067</PDBx:U22>
         <PDBx:U23>0.0721</PDBx:U23>
         <PDBx:U33>0.4033</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2927">
         <PDBx:U11>0.3437</PDBx:U11>
         <PDBx:U12>-0.1260</PDBx:U12>
         <PDBx:U13>-0.0113</PDBx:U13>
         <PDBx:U22>0.3557</PDBx:U22>
         <PDBx:U23>0.0757</PDBx:U23>
         <PDBx:U33>0.4072</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2928">
         <PDBx:U11>0.3456</PDBx:U11>
         <PDBx:U12>-0.1095</PDBx:U12>
         <PDBx:U13>-0.0167</PDBx:U13>
         <PDBx:U22>0.3636</PDBx:U22>
         <PDBx:U23>0.0639</PDBx:U23>
         <PDBx:U33>0.3968</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2929">
         <PDBx:U11>0.4377</PDBx:U11>
         <PDBx:U12>-0.1624</PDBx:U12>
         <PDBx:U13>-0.0260</PDBx:U13>
         <PDBx:U22>0.4113</PDBx:U22>
         <PDBx:U23>0.0589</PDBx:U23>
         <PDBx:U33>0.5130</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2930">
         <PDBx:U11>0.4824</PDBx:U11>
         <PDBx:U12>-0.1802</PDBx:U12>
         <PDBx:U13>-0.0287</PDBx:U13>
         <PDBx:U22>0.4054</PDBx:U22>
         <PDBx:U23>0.0508</PDBx:U23>
         <PDBx:U33>0.5513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2931">
         <PDBx:U11>0.5606</PDBx:U11>
         <PDBx:U12>-0.1853</PDBx:U12>
         <PDBx:U13>-0.0105</PDBx:U13>
         <PDBx:U22>0.4590</PDBx:U22>
         <PDBx:U23>0.0688</PDBx:U23>
         <PDBx:U33>0.6353</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2932">
         <PDBx:U11>0.5711</PDBx:U11>
         <PDBx:U12>-0.1917</PDBx:U12>
         <PDBx:U13>-0.0006</PDBx:U13>
         <PDBx:U22>0.5036</PDBx:U22>
         <PDBx:U23>0.0809</PDBx:U23>
         <PDBx:U33>0.6704</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2933">
         <PDBx:U11>0.6319</PDBx:U11>
         <PDBx:U12>-0.1799</PDBx:U12>
         <PDBx:U13>-0.0043</PDBx:U13>
         <PDBx:U22>0.4687</PDBx:U22>
         <PDBx:U23>0.0707</PDBx:U23>
         <PDBx:U33>0.6816</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>441</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>141</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2934">
         <PDBx:U11>0.3069</PDBx:U11>
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         <PDBx:U13>-0.0004</PDBx:U13>
         <PDBx:U22>0.3548</PDBx:U22>
         <PDBx:U23>0.0870</PDBx:U23>
         <PDBx:U33>0.3878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2935">
         <PDBx:U11>0.3346</PDBx:U11>
         <PDBx:U12>-0.1064</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.4289</PDBx:U22>
         <PDBx:U23>0.0862</PDBx:U23>
         <PDBx:U33>0.4216</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2786</PDBx:U11>
         <PDBx:U12>-0.1027</PDBx:U12>
         <PDBx:U13>-0.0080</PDBx:U13>
         <PDBx:U22>0.3998</PDBx:U22>
         <PDBx:U23>0.0698</PDBx:U23>
         <PDBx:U33>0.3793</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2305</PDBx:U11>
         <PDBx:U12>-0.0862</PDBx:U12>
         <PDBx:U13>-0.0088</PDBx:U13>
         <PDBx:U22>0.3676</PDBx:U22>
         <PDBx:U23>0.0634</PDBx:U23>
         <PDBx:U33>0.3267</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>442</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>142</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2938">
         <PDBx:U11>0.2765</PDBx:U11>
         <PDBx:U12>-0.1162</PDBx:U12>
         <PDBx:U13>-0.0168</PDBx:U13>
         <PDBx:U22>0.3999</PDBx:U22>
         <PDBx:U23>0.0629</PDBx:U23>
         <PDBx:U33>0.3931</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.2385</PDBx:U11>
         <PDBx:U12>-0.1095</PDBx:U12>
         <PDBx:U13>-0.0284</PDBx:U13>
         <PDBx:U22>0.3833</PDBx:U22>
         <PDBx:U23>0.0498</PDBx:U23>
         <PDBx:U33>0.3663</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>-0.0407</PDBx:U13>
         <PDBx:U22>0.3622</PDBx:U22>
         <PDBx:U23>0.0413</PDBx:U23>
         <PDBx:U33>0.3441</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2088</PDBx:U11>
         <PDBx:U12>-0.0886</PDBx:U12>
         <PDBx:U13>-0.0449</PDBx:U13>
         <PDBx:U22>0.3464</PDBx:U22>
         <PDBx:U23>0.0349</PDBx:U23>
         <PDBx:U33>0.3148</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.3322</PDBx:U11>
         <PDBx:U12>-0.1255</PDBx:U12>
         <PDBx:U13>-0.0366</PDBx:U13>
         <PDBx:U22>0.4864</PDBx:U22>
         <PDBx:U23>0.0449</PDBx:U23>
         <PDBx:U33>0.4828</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.3664</PDBx:U11>
         <PDBx:U12>-0.1313</PDBx:U12>
         <PDBx:U13>-0.0237</PDBx:U13>
         <PDBx:U22>0.5493</PDBx:U22>
         <PDBx:U23>0.0521</PDBx:U23>
         <PDBx:U33>0.5445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2944">
         <PDBx:U11>0.4301</PDBx:U11>
         <PDBx:U12>-0.1475</PDBx:U12>
         <PDBx:U13>-0.0118</PDBx:U13>
         <PDBx:U22>0.5908</PDBx:U22>
         <PDBx:U23>0.0649</PDBx:U23>
         <PDBx:U33>0.6046</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2945">
         <PDBx:U11>0.4726</PDBx:U11>
         <PDBx:U12>-0.1521</PDBx:U12>
         <PDBx:U13>-0.0135</PDBx:U13>
         <PDBx:U22>0.5921</PDBx:U22>
         <PDBx:U23>0.0678</PDBx:U23>
         <PDBx:U33>0.6232</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="2946">
         <PDBx:U11>0.4538</PDBx:U11>
         <PDBx:U12>-0.1550</PDBx:U12>
         <PDBx:U13>0.0004</PDBx:U13>
         <PDBx:U22>0.6351</PDBx:U22>
         <PDBx:U23>0.0725</PDBx:U23>
         <PDBx:U33>0.6487</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>443</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>143</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2850</PDBx:U11>
         <PDBx:U12>-0.1150</PDBx:U12>
         <PDBx:U13>-0.0450</PDBx:U13>
         <PDBx:U22>0.3699</PDBx:U22>
         <PDBx:U23>0.0411</PDBx:U23>
         <PDBx:U33>0.3697</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.2970</PDBx:U11>
         <PDBx:U12>-0.1072</PDBx:U12>
         <PDBx:U13>-0.0532</PDBx:U13>
         <PDBx:U22>0.3545</PDBx:U22>
         <PDBx:U23>0.0314</PDBx:U23>
         <PDBx:U33>0.3519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2240</PDBx:U11>
         <PDBx:U12>-0.0842</PDBx:U12>
         <PDBx:U13>-0.0405</PDBx:U13>
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         <PDBx:U23>0.0343</PDBx:U23>
         <PDBx:U33>0.2674</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2264</PDBx:U11>
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         <PDBx:U22>0.2870</PDBx:U22>
         <PDBx:U23>0.0282</PDBx:U23>
         <PDBx:U33>0.2584</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2951">
         <PDBx:U11>0.3269</PDBx:U11>
         <PDBx:U12>-0.1163</PDBx:U12>
         <PDBx:U13>-0.0549</PDBx:U13>
         <PDBx:U22>0.3295</PDBx:U22>
         <PDBx:U23>0.0245</PDBx:U23>
         <PDBx:U33>0.3532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2952">
         <PDBx:U11>0.3715</PDBx:U11>
         <PDBx:U12>-0.1414</PDBx:U12>
         <PDBx:U13>-0.0698</PDBx:U13>
         <PDBx:U22>0.3665</PDBx:U22>
         <PDBx:U23>0.0167</PDBx:U23>
         <PDBx:U33>0.4064</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2953">
         <PDBx:U11>0.4136</PDBx:U11>
         <PDBx:U12>-0.1521</PDBx:U12>
         <PDBx:U13>-0.0704</PDBx:U13>
         <PDBx:U22>0.3463</PDBx:U22>
         <PDBx:U23>0.0069</PDBx:U23>
         <PDBx:U33>0.4185</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2954">
         <PDBx:U11>0.4392</PDBx:U11>
         <PDBx:U12>-0.1433</PDBx:U12>
         <PDBx:U13>-0.0539</PDBx:U13>
         <PDBx:U22>0.3400</PDBx:U22>
         <PDBx:U23>0.0147</PDBx:U23>
         <PDBx:U33>0.4333</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2955">
         <PDBx:U11>0.4422</PDBx:U11>
         <PDBx:U12>-0.1597</PDBx:U12>
         <PDBx:U13>-0.0837</PDBx:U13>
         <PDBx:U22>0.3612</PDBx:U22>
         <PDBx:U23>-0.0094</PDBx:U23>
         <PDBx:U33>0.4343</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>444</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>144</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2956">
         <PDBx:U11>0.2557</PDBx:U11>
         <PDBx:U12>-0.0796</PDBx:U12>
         <PDBx:U13>-0.0266</PDBx:U13>
         <PDBx:U22>0.3185</PDBx:U22>
         <PDBx:U23>0.0448</PDBx:U23>
         <PDBx:U33>0.3027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2957">
         <PDBx:U11>0.2684</PDBx:U11>
         <PDBx:U12>-0.0603</PDBx:U12>
         <PDBx:U13>-0.0169</PDBx:U13>
         <PDBx:U22>0.3390</PDBx:U22>
         <PDBx:U23>0.0467</PDBx:U23>
         <PDBx:U33>0.3078</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2958">
         <PDBx:U11>0.2179</PDBx:U11>
         <PDBx:U12>-0.0518</PDBx:U12>
         <PDBx:U13>-0.0184</PDBx:U13>
         <PDBx:U22>0.3255</PDBx:U22>
         <PDBx:U23>0.0418</PDBx:U23>
         <PDBx:U33>0.2728</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2959">
         <PDBx:U11>0.1973</PDBx:U11>
         <PDBx:U12>-0.0402</PDBx:U12>
         <PDBx:U13>-0.0179</PDBx:U13>
         <PDBx:U22>0.3013</PDBx:U22>
         <PDBx:U23>0.0358</PDBx:U23>
         <PDBx:U33>0.2434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2960">
         <PDBx:U11>0.2875</PDBx:U11>
         <PDBx:U12>-0.0573</PDBx:U12>
         <PDBx:U13>-0.0050</PDBx:U13>
         <PDBx:U22>0.3618</PDBx:U22>
         <PDBx:U23>0.0606</PDBx:U23>
         <PDBx:U33>0.3278</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2961">
         <PDBx:U11>0.2721</PDBx:U11>
         <PDBx:U12>-0.0404</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.3716</PDBx:U22>
         <PDBx:U23>0.0615</PDBx:U23>
         <PDBx:U33>0.3117</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2962">
         <PDBx:U11>0.2738</PDBx:U11>
         <PDBx:U12>-0.0266</PDBx:U12>
         <PDBx:U13>0.0024</PDBx:U13>
         <PDBx:U22>0.3609</PDBx:U22>
         <PDBx:U23>0.0564</PDBx:U23>
         <PDBx:U33>0.3008</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2963">
         <PDBx:U11>0.2470</PDBx:U11>
         <PDBx:U12>-0.0392</PDBx:U12>
         <PDBx:U13>0.0064</PDBx:U13>
         <PDBx:U22>0.3852</PDBx:U22>
         <PDBx:U23>0.0659</PDBx:U23>
         <PDBx:U33>0.2992</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2964">
         <PDBx:U11>0.2371</PDBx:U11>
         <PDBx:U12>-0.0144</PDBx:U12>
         <PDBx:U13>0.0056</PDBx:U13>
         <PDBx:U22>0.3509</PDBx:U22>
         <PDBx:U23>0.0553</PDBx:U23>
         <PDBx:U33>0.2675</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2965">
         <PDBx:U11>0.2401</PDBx:U11>
         <PDBx:U12>-0.0255</PDBx:U12>
         <PDBx:U13>0.0096</PDBx:U13>
         <PDBx:U22>0.4007</PDBx:U22>
         <PDBx:U23>0.0628</PDBx:U23>
         <PDBx:U33>0.2888</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2966">
         <PDBx:U11>0.2109</PDBx:U11>
         <PDBx:U12>-0.0145</PDBx:U12>
         <PDBx:U13>0.0078</PDBx:U13>
         <PDBx:U22>0.3601</PDBx:U22>
         <PDBx:U23>0.0574</PDBx:U23>
         <PDBx:U33>0.2506</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>445</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>145</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2967">
         <PDBx:U11>0.2111</PDBx:U11>
         <PDBx:U12>-0.0560</PDBx:U12>
         <PDBx:U13>-0.0183</PDBx:U13>
         <PDBx:U22>0.3493</PDBx:U22>
         <PDBx:U23>0.0434</PDBx:U23>
         <PDBx:U33>0.2883</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2968">
         <PDBx:U11>0.2423</PDBx:U11>
         <PDBx:U12>-0.0412</PDBx:U12>
         <PDBx:U13>-0.0162</PDBx:U13>
         <PDBx:U22>0.3928</PDBx:U22>
         <PDBx:U23>0.0339</PDBx:U23>
         <PDBx:U33>0.3244</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2969">
         <PDBx:U11>0.2373</PDBx:U11>
         <PDBx:U12>-0.0377</PDBx:U12>
         <PDBx:U13>-0.0267</PDBx:U13>
         <PDBx:U22>0.3790</PDBx:U22>
         <PDBx:U23>0.0269</PDBx:U23>
         <PDBx:U33>0.3185</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2970">
         <PDBx:U11>0.1979</PDBx:U11>
         <PDBx:U12>-0.0263</PDBx:U12>
         <PDBx:U13>-0.0250</PDBx:U13>
         <PDBx:U22>0.3387</PDBx:U22>
         <PDBx:U23>0.0213</PDBx:U23>
         <PDBx:U33>0.2790</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2971">
         <PDBx:U11>0.2097</PDBx:U11>
         <PDBx:U12>-0.0415</PDBx:U12>
         <PDBx:U13>-0.0112</PDBx:U13>
         <PDBx:U22>0.3805</PDBx:U22>
         <PDBx:U23>0.0338</PDBx:U23>
         <PDBx:U33>0.3085</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2972">
         <PDBx:U11>0.2047</PDBx:U11>
         <PDBx:U12>-0.0414</PDBx:U12>
         <PDBx:U13>0.0000</PDBx:U13>
         <PDBx:U22>0.3861</PDBx:U22>
         <PDBx:U23>0.0416</PDBx:U23>
         <PDBx:U33>0.2980</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2973">
         <PDBx:U11>0.2594</PDBx:U11>
         <PDBx:U12>-0.0553</PDBx:U12>
         <PDBx:U13>-0.0186</PDBx:U13>
         <PDBx:U22>0.4346</PDBx:U22>
         <PDBx:U23>0.0361</PDBx:U23>
         <PDBx:U33>0.3739</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>446</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>146</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2974">
         <PDBx:U11>0.2441</PDBx:U11>
         <PDBx:U12>-0.0490</PDBx:U12>
         <PDBx:U13>-0.0386</PDBx:U13>
         <PDBx:U22>0.3772</PDBx:U22>
         <PDBx:U23>0.0278</PDBx:U23>
         <PDBx:U33>0.3230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2975">
         <PDBx:U11>0.2309</PDBx:U11>
         <PDBx:U12>-0.0456</PDBx:U12>
         <PDBx:U13>-0.0508</PDBx:U13>
         <PDBx:U22>0.3549</PDBx:U22>
         <PDBx:U23>0.0237</PDBx:U23>
         <PDBx:U33>0.3009</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2976">
         <PDBx:U11>0.2090</PDBx:U11>
         <PDBx:U12>-0.0404</PDBx:U12>
         <PDBx:U13>-0.0499</PDBx:U13>
         <PDBx:U22>0.3144</PDBx:U22>
         <PDBx:U23>0.0239</PDBx:U23>
         <PDBx:U33>0.2555</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2977">
         <PDBx:U11>0.2131</PDBx:U11>
         <PDBx:U12>-0.0305</PDBx:U12>
         <PDBx:U13>-0.0512</PDBx:U13>
         <PDBx:U22>0.3170</PDBx:U22>
         <PDBx:U23>0.0236</PDBx:U23>
         <PDBx:U33>0.2563</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2978">
         <PDBx:U11>0.2766</PDBx:U11>
         <PDBx:U12>-0.0595</PDBx:U12>
         <PDBx:U13>-0.0654</PDBx:U13>
         <PDBx:U22>0.3916</PDBx:U22>
         <PDBx:U23>0.0216</PDBx:U23>
         <PDBx:U33>0.3407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2979">
         <PDBx:U11>0.3005</PDBx:U11>
         <PDBx:U12>-0.0633</PDBx:U12>
         <PDBx:U13>-0.0696</PDBx:U13>
         <PDBx:U22>0.4449</PDBx:U22>
         <PDBx:U23>0.0198</PDBx:U23>
         <PDBx:U33>0.3979</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>CYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>447</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>CYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>147</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2980">
         <PDBx:U11>0.2050</PDBx:U11>
         <PDBx:U12>-0.0426</PDBx:U12>
         <PDBx:U13>-0.0420</PDBx:U13>
         <PDBx:U22>0.2855</PDBx:U22>
         <PDBx:U23>0.0236</PDBx:U23>
         <PDBx:U33>0.2321</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2981">
         <PDBx:U11>0.2610</PDBx:U11>
         <PDBx:U12>-0.0331</PDBx:U12>
         <PDBx:U13>-0.0335</PDBx:U13>
         <PDBx:U22>0.3179</PDBx:U22>
         <PDBx:U23>0.0215</PDBx:U23>
         <PDBx:U33>0.2645</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2982">
         <PDBx:U11>0.2277</PDBx:U11>
         <PDBx:U12>-0.0227</PDBx:U12>
         <PDBx:U13>-0.0240</PDBx:U13>
         <PDBx:U22>0.3026</PDBx:U22>
         <PDBx:U23>0.0221</PDBx:U23>
         <PDBx:U33>0.2454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2983">
         <PDBx:U11>0.2873</PDBx:U11>
         <PDBx:U12>-0.0167</PDBx:U12>
         <PDBx:U13>-0.0207</PDBx:U13>
         <PDBx:U22>0.3537</PDBx:U22>
         <PDBx:U23>0.0210</PDBx:U23>
         <PDBx:U33>0.2968</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2984">
         <PDBx:U11>0.2623</PDBx:U11>
         <PDBx:U12>-0.0340</PDBx:U12>
         <PDBx:U13>-0.0256</PDBx:U13>
         <PDBx:U22>0.2934</PDBx:U22>
         <PDBx:U23>0.0213</PDBx:U23>
         <PDBx:U33>0.2492</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2985">
         <PDBx:U11>0.3418</PDBx:U11>
         <PDBx:U12>-0.0443</PDBx:U12>
         <PDBx:U13>-0.0332</PDBx:U13>
         <PDBx:U22>0.3408</PDBx:U22>
         <PDBx:U23>0.0157</PDBx:U23>
         <PDBx:U33>0.3061</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2986">
         <PDBx:U11>0.4107</PDBx:U11>
         <PDBx:U12>-0.0402</PDBx:U12>
         <PDBx:U13>-0.0222</PDBx:U13>
         <PDBx:U22>0.3780</PDBx:U22>
         <PDBx:U23>0.0151</PDBx:U23>
         <PDBx:U33>0.3595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2987">
         <PDBx:U11>0.3595</PDBx:U11>
         <PDBx:U12>-0.0426</PDBx:U12>
         <PDBx:U13>-0.0409</PDBx:U13>
         <PDBx:U22>0.3446</PDBx:U22>
         <PDBx:U23>0.0092</PDBx:U23>
         <PDBx:U33>0.2974</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>448</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>148</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2988">
         <PDBx:U11>0.2276</PDBx:U11>
         <PDBx:U12>-0.0220</PDBx:U12>
         <PDBx:U13>-0.0192</PDBx:U13>
         <PDBx:U22>0.3269</PDBx:U22>
         <PDBx:U23>0.0235</PDBx:U23>
         <PDBx:U33>0.2649</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2989">
         <PDBx:U11>0.2064</PDBx:U11>
         <PDBx:U12>-0.0143</PDBx:U12>
         <PDBx:U13>-0.0123</PDBx:U13>
         <PDBx:U22>0.3238</PDBx:U22>
         <PDBx:U23>0.0200</PDBx:U23>
         <PDBx:U33>0.2558</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2990">
         <PDBx:U11>0.2160</PDBx:U11>
         <PDBx:U12>-0.0105</PDBx:U12>
         <PDBx:U13>-0.0156</PDBx:U13>
         <PDBx:U22>0.3367</PDBx:U22>
         <PDBx:U23>0.0154</PDBx:U23>
         <PDBx:U33>0.2758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2991">
         <PDBx:U11>0.1933</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>-0.0113</PDBx:U13>
         <PDBx:U22>0.3119</PDBx:U22>
         <PDBx:U23>0.0118</PDBx:U23>
         <PDBx:U33>0.2561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2992">
         <PDBx:U11>0.2207</PDBx:U11>
         <PDBx:U12>-0.0127</PDBx:U12>
         <PDBx:U13>-0.0070</PDBx:U13>
         <PDBx:U22>0.3504</PDBx:U22>
         <PDBx:U23>0.0198</PDBx:U23>
         <PDBx:U33>0.2744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2993">
         <PDBx:U11>0.2334</PDBx:U11>
         <PDBx:U12>-0.0059</PDBx:U12>
         <PDBx:U13>-0.0021</PDBx:U13>
         <PDBx:U22>0.3647</PDBx:U22>
         <PDBx:U23>0.0125</PDBx:U23>
         <PDBx:U33>0.2849</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2994">
         <PDBx:U11>0.2184</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>0.0008</PDBx:U13>
         <PDBx:U22>0.3632</PDBx:U22>
         <PDBx:U23>0.0158</PDBx:U23>
         <PDBx:U33>0.2644</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2995">
         <PDBx:U11>0.2083</PDBx:U11>
         <PDBx:U12>-0.0076</PDBx:U12>
         <PDBx:U13>0.0017</PDBx:U13>
         <PDBx:U22>0.3638</PDBx:U22>
         <PDBx:U23>0.0174</PDBx:U23>
         <PDBx:U33>0.2593</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2996">
         <PDBx:U11>0.1793</PDBx:U11>
         <PDBx:U12>-0.0055</PDBx:U12>
         <PDBx:U13>0.0053</PDBx:U13>
         <PDBx:U22>0.3550</PDBx:U22>
         <PDBx:U23>0.0210</PDBx:U23>
         <PDBx:U33>0.2230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>449</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>149</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2997">
         <PDBx:U11>0.2176</PDBx:U11>
         <PDBx:U12>-0.0114</PDBx:U12>
         <PDBx:U13>-0.0225</PDBx:U13>
         <PDBx:U22>0.3408</PDBx:U22>
         <PDBx:U23>0.0158</PDBx:U23>
         <PDBx:U33>0.2847</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2998">
         <PDBx:U11>0.1975</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>-0.0269</PDBx:U13>
         <PDBx:U22>0.3235</PDBx:U22>
         <PDBx:U23>0.0139</PDBx:U23>
         <PDBx:U33>0.2771</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="2999">
         <PDBx:U11>0.1955</PDBx:U11>
         <PDBx:U12>-0.0031</PDBx:U12>
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         <PDBx:U23>0.0202</PDBx:U23>
         <PDBx:U33>0.2596</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3000">
         <PDBx:U11>0.2048</PDBx:U11>
         <PDBx:U12>0.0036</PDBx:U12>
         <PDBx:U13>-0.0306</PDBx:U13>
         <PDBx:U22>0.3017</PDBx:U22>
         <PDBx:U23>0.0207</PDBx:U23>
         <PDBx:U33>0.2733</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3001">
         <PDBx:U11>0.2519</PDBx:U11>
         <PDBx:U12>-0.0039</PDBx:U12>
         <PDBx:U13>-0.0330</PDBx:U13>
         <PDBx:U22>0.3877</PDBx:U22>
         <PDBx:U23>0.0134</PDBx:U23>
         <PDBx:U33>0.3452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3002">
         <PDBx:U11>0.3213</PDBx:U11>
         <PDBx:U12>-0.0033</PDBx:U12>
         <PDBx:U13>-0.0242</PDBx:U13>
         <PDBx:U22>0.4676</PDBx:U22>
         <PDBx:U23>0.0087</PDBx:U23>
         <PDBx:U33>0.4252</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>450</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>150</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3003">
         <PDBx:U11>0.2357</PDBx:U11>
         <PDBx:U12>-0.0091</PDBx:U12>
         <PDBx:U13>-0.0369</PDBx:U13>
         <PDBx:U22>0.3250</PDBx:U22>
         <PDBx:U23>0.0238</PDBx:U23>
         <PDBx:U33>0.2752</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3004">
         <PDBx:U11>0.2320</PDBx:U11>
         <PDBx:U12>-0.0071</PDBx:U12>
         <PDBx:U13>-0.0383</PDBx:U13>
         <PDBx:U22>0.2944</PDBx:U22>
         <PDBx:U23>0.0287</PDBx:U23>
         <PDBx:U33>0.2438</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3005">
         <PDBx:U11>0.2243</PDBx:U11>
         <PDBx:U12>-0.0046</PDBx:U12>
         <PDBx:U13>-0.0228</PDBx:U13>
         <PDBx:U22>0.2746</PDBx:U22>
         <PDBx:U23>0.0284</PDBx:U23>
         <PDBx:U33>0.2315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3006">
         <PDBx:U11>0.2151</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>-0.0196</PDBx:U13>
         <PDBx:U22>0.2502</PDBx:U22>
         <PDBx:U23>0.0342</PDBx:U23>
         <PDBx:U33>0.2147</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3007">
         <PDBx:U11>0.2776</PDBx:U11>
         <PDBx:U12>-0.0140</PDBx:U12>
         <PDBx:U13>-0.0445</PDBx:U13>
         <PDBx:U22>0.3230</PDBx:U22>
         <PDBx:U23>0.0280</PDBx:U23>
         <PDBx:U33>0.2591</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3008">
         <PDBx:U11>0.2891</PDBx:U11>
         <PDBx:U12>-0.0193</PDBx:U12>
         <PDBx:U13>-0.0639</PDBx:U13>
         <PDBx:U22>0.3471</PDBx:U22>
         <PDBx:U23>0.0285</PDBx:U23>
         <PDBx:U33>0.2758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3009">
         <PDBx:U11>0.2864</PDBx:U11>
         <PDBx:U12>-0.0107</PDBx:U12>
         <PDBx:U13>-0.0397</PDBx:U13>
         <PDBx:U22>0.3045</PDBx:U22>
         <PDBx:U23>0.0316</PDBx:U23>
         <PDBx:U33>0.2322</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3010">
         <PDBx:U11>0.3565</PDBx:U11>
         <PDBx:U12>-0.0295</PDBx:U12>
         <PDBx:U13>-0.0726</PDBx:U13>
         <PDBx:U22>0.3964</PDBx:U22>
         <PDBx:U23>0.0232</PDBx:U23>
         <PDBx:U33>0.3142</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>451</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>151</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3011">
         <PDBx:U11>0.2050</PDBx:U11>
         <PDBx:U12>-0.0065</PDBx:U12>
         <PDBx:U13>-0.0135</PDBx:U13>
         <PDBx:U22>0.2641</PDBx:U22>
         <PDBx:U23>0.0231</PDBx:U23>
         <PDBx:U33>0.2191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3012">
         <PDBx:U11>0.1898</PDBx:U11>
         <PDBx:U12>-0.0055</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.2481</PDBx:U22>
         <PDBx:U23>0.0214</PDBx:U23>
         <PDBx:U33>0.2088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.2084</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>0.0016</PDBx:U13>
         <PDBx:U22>0.2720</PDBx:U22>
         <PDBx:U23>0.0187</PDBx:U23>
         <PDBx:U33>0.2495</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3014">
         <PDBx:U11>0.2342</PDBx:U11>
         <PDBx:U12>-0.0064</PDBx:U12>
         <PDBx:U13>0.0096</PDBx:U13>
         <PDBx:U22>0.2847</PDBx:U22>
         <PDBx:U23>0.0218</PDBx:U23>
         <PDBx:U33>0.2750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2188</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>0.0052</PDBx:U13>
         <PDBx:U22>0.2943</PDBx:U22>
         <PDBx:U23>0.0169</PDBx:U23>
         <PDBx:U33>0.2471</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3016">
         <PDBx:U11>0.2358</PDBx:U11>
         <PDBx:U12>-0.0043</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.2959</PDBx:U22>
         <PDBx:U23>0.0194</PDBx:U23>
         <PDBx:U33>0.2418</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3017">
         <PDBx:U11>0.2226</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>0.0153</PDBx:U13>
         <PDBx:U22>0.3092</PDBx:U22>
         <PDBx:U23>0.0137</PDBx:U23>
         <PDBx:U33>0.2661</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3018">
         <PDBx:U11>0.1974</PDBx:U11>
         <PDBx:U12>-0.0007</PDBx:U12>
         <PDBx:U13>0.0109</PDBx:U13>
         <PDBx:U22>0.2703</PDBx:U22>
         <PDBx:U23>0.0192</PDBx:U23>
         <PDBx:U33>0.2116</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>452</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>152</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3019">
         <PDBx:U11>0.2229</PDBx:U11>
         <PDBx:U12>-0.0027</PDBx:U12>
         <PDBx:U13>-0.0041</PDBx:U13>
         <PDBx:U22>0.3040</PDBx:U22>
         <PDBx:U23>0.0126</PDBx:U23>
         <PDBx:U33>0.2832</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3020">
         <PDBx:U11>0.2266</PDBx:U11>
         <PDBx:U12>-0.0004</PDBx:U12>
         <PDBx:U13>-0.0023</PDBx:U13>
         <PDBx:U22>0.3084</PDBx:U22>
         <PDBx:U23>0.0059</PDBx:U23>
         <PDBx:U33>0.3072</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3021">
         <PDBx:U11>0.2726</PDBx:U11>
         <PDBx:U12>0.0031</PDBx:U12>
         <PDBx:U13>-0.0037</PDBx:U13>
         <PDBx:U22>0.3266</PDBx:U22>
         <PDBx:U23>0.0154</PDBx:U23>
         <PDBx:U33>0.3477</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3022">
         <PDBx:U11>0.2618</PDBx:U11>
         <PDBx:U12>0.0005</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.2992</PDBx:U22>
         <PDBx:U23>0.0149</PDBx:U23>
         <PDBx:U33>0.3441</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3023">
         <PDBx:U11>0.1843</PDBx:U11>
         <PDBx:U12>0.0045</PDBx:U12>
         <PDBx:U13>-0.0069</PDBx:U13>
         <PDBx:U22>0.2890</PDBx:U22>
         <PDBx:U23>-0.0023</PDBx:U23>
         <PDBx:U33>0.2818</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3024">
         <PDBx:U11>0.1813</PDBx:U11>
         <PDBx:U12>0.0101</PDBx:U12>
         <PDBx:U13>-0.0047</PDBx:U13>
         <PDBx:U22>0.2830</PDBx:U22>
         <PDBx:U23>-0.0129</PDBx:U23>
         <PDBx:U33>0.2983</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3025">
         <PDBx:U11>0.1810</PDBx:U11>
         <PDBx:U12>0.0031</PDBx:U12>
         <PDBx:U13>0.0026</PDBx:U13>
         <PDBx:U22>0.2807</PDBx:U22>
         <PDBx:U23>-0.0252</PDBx:U23>
         <PDBx:U33>0.3048</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3026">
         <PDBx:U11>0.2039</PDBx:U11>
         <PDBx:U12>0.0172</PDBx:U12>
         <PDBx:U13>-0.0062</PDBx:U13>
         <PDBx:U22>0.3327</PDBx:U22>
         <PDBx:U23>-0.0212</PDBx:U23>
         <PDBx:U33>0.3354</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>453</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>153</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3027">
         <PDBx:U11>0.2586</PDBx:U11>
         <PDBx:U12>0.0080</PDBx:U12>
         <PDBx:U13>-0.0140</PDBx:U13>
         <PDBx:U22>0.3075</PDBx:U22>
         <PDBx:U23>0.0251</PDBx:U23>
         <PDBx:U33>0.3210</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3028">
         <PDBx:U11>0.3066</PDBx:U11>
         <PDBx:U12>0.0150</PDBx:U12>
         <PDBx:U13>-0.0188</PDBx:U13>
         <PDBx:U22>0.3320</PDBx:U22>
         <PDBx:U23>0.0375</PDBx:U23>
         <PDBx:U33>0.3615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3029">
         <PDBx:U11>0.3181</PDBx:U11>
         <PDBx:U12>0.0109</PDBx:U12>
         <PDBx:U13>-0.0124</PDBx:U13>
         <PDBx:U22>0.3172</PDBx:U22>
         <PDBx:U23>0.0502</PDBx:U23>
         <PDBx:U33>0.3424</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3030">
         <PDBx:U11>0.3563</PDBx:U11>
         <PDBx:U12>0.0143</PDBx:U12>
         <PDBx:U13>-0.0094</PDBx:U13>
         <PDBx:U22>0.3303</PDBx:U22>
         <PDBx:U23>0.0622</PDBx:U23>
         <PDBx:U33>0.3747</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3031">
         <PDBx:U11>0.3162</PDBx:U11>
         <PDBx:U12>0.0226</PDBx:U12>
         <PDBx:U13>-0.0356</PDBx:U13>
         <PDBx:U22>0.3544</PDBx:U22>
         <PDBx:U23>0.0431</PDBx:U23>
         <PDBx:U33>0.3714</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3032">
         <PDBx:U11>0.3347</PDBx:U11>
         <PDBx:U12>0.0282</PDBx:U12>
         <PDBx:U13>-0.0394</PDBx:U13>
         <PDBx:U22>0.4034</PDBx:U22>
         <PDBx:U23>0.0330</PDBx:U23>
         <PDBx:U33>0.4229</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3033">
         <PDBx:U11>0.3040</PDBx:U11>
         <PDBx:U12>0.0333</PDBx:U12>
         <PDBx:U13>-0.0565</PDBx:U13>
         <PDBx:U22>0.3925</PDBx:U22>
         <PDBx:U23>0.0400</PDBx:U23>
         <PDBx:U33>0.3978</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3034">
         <PDBx:U11>0.3598</PDBx:U11>
         <PDBx:U12>0.0379</PDBx:U12>
         <PDBx:U13>-0.0324</PDBx:U13>
         <PDBx:U22>0.4195</PDBx:U22>
         <PDBx:U23>0.0270</PDBx:U23>
         <PDBx:U33>0.4713</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>454</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>154</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3035">
         <PDBx:U11>0.2655</PDBx:U11>
         <PDBx:U12>0.0047</PDBx:U12>
         <PDBx:U13>-0.0086</PDBx:U13>
         <PDBx:U22>0.2685</PDBx:U22>
         <PDBx:U23>0.0486</PDBx:U23>
         <PDBx:U33>0.2693</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3036">
         <PDBx:U11>0.3377</PDBx:U11>
         <PDBx:U12>0.0027</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.3193</PDBx:U22>
         <PDBx:U23>0.0593</PDBx:U23>
         <PDBx:U33>0.3071</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3037">
         <PDBx:U11>0.3610</PDBx:U11>
         <PDBx:U12>-0.0040</PDBx:U12>
         <PDBx:U13>0.0196</PDBx:U13>
         <PDBx:U22>0.3370</PDBx:U22>
         <PDBx:U23>0.0600</PDBx:U23>
         <PDBx:U33>0.3361</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3038">
         <PDBx:U11>0.3977</PDBx:U11>
         <PDBx:U12>-0.0053</PDBx:U12>
         <PDBx:U13>0.0297</PDBx:U13>
         <PDBx:U22>0.3529</PDBx:U22>
         <PDBx:U23>0.0733</PDBx:U23>
         <PDBx:U33>0.3552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3039">
         <PDBx:U11>0.3555</PDBx:U11>
         <PDBx:U12>0.0014</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.3393</PDBx:U22>
         <PDBx:U23>0.0557</PDBx:U23>
         <PDBx:U33>0.2958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3040">
         <PDBx:U11>0.3870</PDBx:U11>
         <PDBx:U12>0.0011</PDBx:U12>
         <PDBx:U13>0.0038</PDBx:U13>
         <PDBx:U22>0.3497</PDBx:U22>
         <PDBx:U23>0.0633</PDBx:U23>
         <PDBx:U33>0.2866</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3041">
         <PDBx:U11>0.4015</PDBx:U11>
         <PDBx:U12>0.0047</PDBx:U12>
         <PDBx:U13>-0.0011</PDBx:U13>
         <PDBx:U22>0.3472</PDBx:U22>
         <PDBx:U23>0.0761</PDBx:U23>
         <PDBx:U33>0.2726</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3042">
         <PDBx:U11>0.3678</PDBx:U11>
         <PDBx:U12>-0.0013</PDBx:U12>
         <PDBx:U13>0.0189</PDBx:U13>
         <PDBx:U22>0.3332</PDBx:U22>
         <PDBx:U23>0.0564</PDBx:U23>
         <PDBx:U33>0.2633</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>455</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>155</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3043">
         <PDBx:U11>0.7800</PDBx:U11>
         <PDBx:U12>-0.1567</PDBx:U12>
         <PDBx:U13>0.1627</PDBx:U13>
         <PDBx:U22>0.3775</PDBx:U22>
         <PDBx:U23>-0.1047</PDBx:U23>
         <PDBx:U33>0.3953</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3044">
         <PDBx:U11>0.8468</PDBx:U11>
         <PDBx:U12>-0.1781</PDBx:U12>
         <PDBx:U13>0.1997</PDBx:U13>
         <PDBx:U22>0.4484</PDBx:U22>
         <PDBx:U23>-0.1226</PDBx:U23>
         <PDBx:U33>0.4622</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3045">
         <PDBx:U11>0.8733</PDBx:U11>
         <PDBx:U12>-0.1824</PDBx:U12>
         <PDBx:U13>0.2451</PDBx:U13>
         <PDBx:U22>0.4077</PDBx:U22>
         <PDBx:U23>-0.1126</PDBx:U23>
         <PDBx:U33>0.4481</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3046">
         <PDBx:U11>0.8744</PDBx:U11>
         <PDBx:U12>-0.1960</PDBx:U12>
         <PDBx:U13>0.2631</PDBx:U13>
         <PDBx:U22>0.3938</PDBx:U22>
         <PDBx:U23>-0.1100</PDBx:U23>
         <PDBx:U33>0.4326</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3047">
         <PDBx:U11>0.8252</PDBx:U11>
         <PDBx:U12>-0.1809</PDBx:U12>
         <PDBx:U13>0.1959</PDBx:U13>
         <PDBx:U22>0.5219</PDBx:U22>
         <PDBx:U23>-0.1273</PDBx:U23>
         <PDBx:U33>0.5462</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3048">
         <PDBx:U11>0.9067</PDBx:U11>
         <PDBx:U12>-0.1729</PDBx:U12>
         <PDBx:U13>0.2118</PDBx:U13>
         <PDBx:U22>0.6028</PDBx:U22>
         <PDBx:U23>-0.1252</PDBx:U23>
         <PDBx:U33>0.6599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>456</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>156</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3049">
         <PDBx:U11>0.8408</PDBx:U11>
         <PDBx:U12>-0.1691</PDBx:U12>
         <PDBx:U13>0.2616</PDBx:U13>
         <PDBx:U22>0.3321</PDBx:U22>
         <PDBx:U23>-0.1040</PDBx:U23>
         <PDBx:U33>0.4107</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3050">
         <PDBx:U11>0.9769</PDBx:U11>
         <PDBx:U12>-0.1720</PDBx:U12>
         <PDBx:U13>0.3041</PDBx:U13>
         <PDBx:U22>0.4055</PDBx:U22>
         <PDBx:U23>-0.0950</PDBx:U23>
         <PDBx:U33>0.5176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3051">
         <PDBx:U11>1.0491</PDBx:U11>
         <PDBx:U12>-0.1504</PDBx:U12>
         <PDBx:U13>0.2984</PDBx:U13>
         <PDBx:U22>0.4254</PDBx:U22>
         <PDBx:U23>-0.0545</PDBx:U23>
         <PDBx:U33>0.5373</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3052">
         <PDBx:U11>1.0512</PDBx:U11>
         <PDBx:U12>-0.1498</PDBx:U12>
         <PDBx:U13>0.3308</PDBx:U13>
         <PDBx:U22>0.3744</PDBx:U22>
         <PDBx:U23>-0.0419</PDBx:U23>
         <PDBx:U33>0.5189</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>457</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>157</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3053">
         <PDBx:U11>1.0031</PDBx:U11>
         <PDBx:U12>-0.1334</PDBx:U12>
         <PDBx:U13>0.2538</PDBx:U13>
         <PDBx:U22>0.3924</PDBx:U22>
         <PDBx:U23>-0.0330</PDBx:U23>
         <PDBx:U33>0.4715</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3054">
         <PDBx:U11>1.1661</PDBx:U11>
         <PDBx:U12>-0.1115</PDBx:U12>
         <PDBx:U13>0.2384</PDBx:U13>
         <PDBx:U22>0.5087</PDBx:U22>
         <PDBx:U23>0.0089</PDBx:U23>
         <PDBx:U33>0.5906</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3055">
         <PDBx:U11>1.2700</PDBx:U11>
         <PDBx:U12>-0.1191</PDBx:U12>
         <PDBx:U13>0.2636</PDBx:U13>
         <PDBx:U22>0.5459</PDBx:U22>
         <PDBx:U23>0.0198</PDBx:U23>
         <PDBx:U33>0.6032</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3056">
         <PDBx:U11>1.3308</PDBx:U11>
         <PDBx:U12>-0.1047</PDBx:U12>
         <PDBx:U13>0.2657</PDBx:U13>
         <PDBx:U22>0.5566</PDBx:U22>
         <PDBx:U23>0.0536</PDBx:U23>
         <PDBx:U33>0.6278</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3057">
         <PDBx:U11>1.1487</PDBx:U11>
         <PDBx:U12>-0.0931</PDBx:U12>
         <PDBx:U13>0.1761</PDBx:U13>
         <PDBx:U22>0.5197</PDBx:U22>
         <PDBx:U23>0.0308</PDBx:U23>
         <PDBx:U33>0.5785</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3058">
         <PDBx:U11>1.1632</PDBx:U11>
         <PDBx:U12>-0.1045</PDBx:U12>
         <PDBx:U13>0.1515</PDBx:U13>
         <PDBx:U22>0.5341</PDBx:U22>
         <PDBx:U23>0.0166</PDBx:U23>
         <PDBx:U33>0.5306</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3059">
         <PDBx:U11>1.2095</PDBx:U11>
         <PDBx:U12>-0.0687</PDBx:U12>
         <PDBx:U13>0.1567</PDBx:U13>
         <PDBx:U22>0.5381</PDBx:U22>
         <PDBx:U23>0.0778</PDBx:U23>
         <PDBx:U33>0.6187</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>458</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>158</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3060">
         <PDBx:U11>1.2673</PDBx:U11>
         <PDBx:U12>-0.1406</PDBx:U12>
         <PDBx:U13>0.2849</PDBx:U13>
         <PDBx:U22>0.5423</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.5659</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3061">
         <PDBx:U11>1.3930</PDBx:U11>
         <PDBx:U12>-0.1462</PDBx:U12>
         <PDBx:U13>0.3145</PDBx:U13>
         <PDBx:U22>0.6061</PDBx:U22>
         <PDBx:U23>0.0055</PDBx:U23>
         <PDBx:U33>0.6034</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3062">
         <PDBx:U11>1.3883</PDBx:U11>
         <PDBx:U12>-0.1568</PDBx:U12>
         <PDBx:U13>0.3557</PDBx:U13>
         <PDBx:U22>0.6022</PDBx:U22>
         <PDBx:U23>-0.0148</PDBx:U23>
         <PDBx:U33>0.6502</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3063">
         <PDBx:U11>1.4377</PDBx:U11>
         <PDBx:U12>-0.1578</PDBx:U12>
         <PDBx:U13>0.3733</PDBx:U13>
         <PDBx:U22>0.6260</PDBx:U22>
         <PDBx:U23>-0.0128</PDBx:U23>
         <PDBx:U33>0.6684</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3064">
         <PDBx:U11>1.4170</PDBx:U11>
         <PDBx:U12>-0.1494</PDBx:U12>
         <PDBx:U13>0.2935</PDBx:U13>
         <PDBx:U22>0.6397</PDBx:U22>
         <PDBx:U23>-0.0097</PDBx:U23>
         <PDBx:U33>0.5763</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3065">
         <PDBx:U11>1.4824</PDBx:U11>
         <PDBx:U12>-0.1317</PDBx:U12>
         <PDBx:U13>0.2338</PDBx:U13>
         <PDBx:U22>0.7010</PDBx:U22>
         <PDBx:U23>0.0090</PDBx:U23>
         <PDBx:U33>0.5924</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3066">
         <PDBx:U11>1.5980</PDBx:U11>
         <PDBx:U12>-0.1134</PDBx:U12>
         <PDBx:U13>0.2135</PDBx:U13>
         <PDBx:U22>0.7575</PDBx:U22>
         <PDBx:U23>0.0467</PDBx:U23>
         <PDBx:U33>0.6302</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3067">
         <PDBx:U11>1.4507</PDBx:U11>
         <PDBx:U12>-0.1322</PDBx:U12>
         <PDBx:U13>0.1897</PDBx:U13>
         <PDBx:U22>0.7292</PDBx:U22>
         <PDBx:U23>-0.0109</PDBx:U23>
         <PDBx:U33>0.6070</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3068">
         <PDBx:U11>1.6589</PDBx:U11>
         <PDBx:U12>-0.0970</PDBx:U12>
         <PDBx:U13>0.1474</PDBx:U13>
         <PDBx:U22>0.8165</PDBx:U22>
         <PDBx:U23>0.0638</PDBx:U23>
         <PDBx:U33>0.6608</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3069">
         <PDBx:U11>1.4969</PDBx:U11>
         <PDBx:U12>-0.1156</PDBx:U12>
         <PDBx:U13>0.1253</PDBx:U13>
         <PDBx:U22>0.7763</PDBx:U22>
         <PDBx:U23>0.0065</PDBx:U23>
         <PDBx:U33>0.6281</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3070">
         <PDBx:U11>1.5771</PDBx:U11>
         <PDBx:U12>-0.0983</PDBx:U12>
         <PDBx:U13>0.1027</PDBx:U13>
         <PDBx:U22>0.7948</PDBx:U22>
         <PDBx:U23>0.0435</PDBx:U23>
         <PDBx:U33>0.6312</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3071">
         <PDBx:U11>1.6184</PDBx:U11>
         <PDBx:U12>-0.0833</PDBx:U12>
         <PDBx:U13>0.0318</PDBx:U13>
         <PDBx:U22>0.8329</PDBx:U22>
         <PDBx:U23>0.0621</PDBx:U23>
         <PDBx:U33>0.6503</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>459</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>159</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3072">
         <PDBx:U11>1.3017</PDBx:U11>
         <PDBx:U12>-0.1624</PDBx:U12>
         <PDBx:U13>0.3676</PDBx:U13>
         <PDBx:U22>0.5426</PDBx:U22>
         <PDBx:U23>-0.0330</PDBx:U23>
         <PDBx:U33>0.6402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3073">
         <PDBx:U11>1.3150</PDBx:U11>
         <PDBx:U12>-0.1694</PDBx:U12>
         <PDBx:U13>0.3971</PDBx:U13>
         <PDBx:U22>0.5544</PDBx:U22>
         <PDBx:U23>-0.0523</PDBx:U23>
         <PDBx:U33>0.6973</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3074">
         <PDBx:U11>1.3309</PDBx:U11>
         <PDBx:U12>-0.1579</PDBx:U12>
         <PDBx:U13>0.4075</PDBx:U13>
         <PDBx:U22>0.5634</PDBx:U22>
         <PDBx:U23>-0.0446</PDBx:U23>
         <PDBx:U33>0.7488</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3075">
         <PDBx:U11>1.3312</PDBx:U11>
         <PDBx:U12>-0.1621</PDBx:U12>
         <PDBx:U13>0.4257</PDBx:U13>
         <PDBx:U22>0.5765</PDBx:U22>
         <PDBx:U23>-0.0633</PDBx:U23>
         <PDBx:U33>0.7905</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3076">
         <PDBx:U11>1.2161</PDBx:U11>
         <PDBx:U12>-0.1878</PDBx:U12>
         <PDBx:U13>0.3960</PDBx:U13>
         <PDBx:U22>0.5018</PDBx:U22>
         <PDBx:U23>-0.0938</PDBx:U23>
         <PDBx:U33>0.6583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3077">
         <PDBx:U11>1.0534</PDBx:U11>
         <PDBx:U12>-0.1875</PDBx:U12>
         <PDBx:U13>0.3690</PDBx:U13>
         <PDBx:U22>0.4039</PDBx:U22>
         <PDBx:U23>-0.1010</PDBx:U23>
         <PDBx:U33>0.5497</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3078">
         <PDBx:U11>1.2661</PDBx:U11>
         <PDBx:U12>-0.1998</PDBx:U12>
         <PDBx:U13>0.3886</PDBx:U13>
         <PDBx:U22>0.5548</PDBx:U22>
         <PDBx:U23>-0.0960</PDBx:U23>
         <PDBx:U33>0.6886</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>460</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>160</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3079">
         <PDBx:U11>1.3783</PDBx:U11>
         <PDBx:U12>-0.1412</PDBx:U12>
         <PDBx:U13>0.3925</PDBx:U13>
         <PDBx:U22>0.5920</PDBx:U22>
         <PDBx:U23>-0.0140</PDBx:U23>
         <PDBx:U33>0.7815</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3080">
         <PDBx:U11>1.4106</PDBx:U11>
         <PDBx:U12>-0.1258</PDBx:U12>
         <PDBx:U13>0.3993</PDBx:U13>
         <PDBx:U22>0.6127</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.8501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3081">
         <PDBx:U11>1.4779</PDBx:U11>
         <PDBx:U12>-0.1277</PDBx:U12>
         <PDBx:U13>0.4268</PDBx:U13>
         <PDBx:U22>0.6555</PDBx:U22>
         <PDBx:U23>-0.0051</PDBx:U23>
         <PDBx:U33>0.9228</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3082">
         <PDBx:U11>1.5538</PDBx:U11>
         <PDBx:U12>-0.1277</PDBx:U12>
         <PDBx:U13>0.4366</PDBx:U13>
         <PDBx:U22>0.6956</PDBx:U22>
         <PDBx:U23>0.0140</PDBx:U23>
         <PDBx:U33>0.9561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3083">
         <PDBx:U11>1.4596</PDBx:U11>
         <PDBx:U12>-0.1032</PDBx:U12>
         <PDBx:U13>0.3789</PDBx:U13>
         <PDBx:U22>0.6296</PDBx:U22>
         <PDBx:U23>0.0409</PDBx:U23>
         <PDBx:U33>0.8744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3084">
         <PDBx:U11>1.4115</PDBx:U11>
         <PDBx:U12>-0.0931</PDBx:U12>
         <PDBx:U13>0.3525</PDBx:U13>
         <PDBx:U22>0.6088</PDBx:U22>
         <PDBx:U23>0.0467</PDBx:U23>
         <PDBx:U33>0.8587</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3085">
         <PDBx:U11>1.3133</PDBx:U11>
         <PDBx:U12>-0.0932</PDBx:U12>
         <PDBx:U13>0.3580</PDBx:U13>
         <PDBx:U22>0.5507</PDBx:U22>
         <PDBx:U23>0.0194</PDBx:U23>
         <PDBx:U33>0.8259</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3086">
         <PDBx:U11>1.4437</PDBx:U11>
         <PDBx:U12>-0.0775</PDBx:U12>
         <PDBx:U13>0.3110</PDBx:U13>
         <PDBx:U22>0.6494</PDBx:U22>
         <PDBx:U23>0.0752</PDBx:U23>
         <PDBx:U33>0.8693</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3087">
         <PDBx:U11>1.2335</PDBx:U11>
         <PDBx:U12>-0.0786</PDBx:U12>
         <PDBx:U13>0.3308</PDBx:U13>
         <PDBx:U22>0.5140</PDBx:U22>
         <PDBx:U23>0.0235</PDBx:U23>
         <PDBx:U33>0.7907</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3088">
         <PDBx:U11>1.3453</PDBx:U11>
         <PDBx:U12>-0.0619</PDBx:U12>
         <PDBx:U13>0.2751</PDBx:U13>
         <PDBx:U22>0.6077</PDBx:U22>
         <PDBx:U23>0.0772</PDBx:U23>
         <PDBx:U33>0.8287</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3089">
         <PDBx:U11>1.2592</PDBx:U11>
         <PDBx:U12>-0.0619</PDBx:U12>
         <PDBx:U13>0.2878</PDBx:U13>
         <PDBx:U22>0.5612</PDBx:U22>
         <PDBx:U23>0.0524</PDBx:U23>
         <PDBx:U33>0.8103</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PHE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>461</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PHE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>161</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3090">
         <PDBx:U11>1.8895</PDBx:U11>
         <PDBx:U12>0.0108</PDBx:U12>
         <PDBx:U13>0.3872</PDBx:U13>
         <PDBx:U22>0.7847</PDBx:U22>
         <PDBx:U23>0.2888</PDBx:U23>
         <PDBx:U33>1.2703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3091">
         <PDBx:U11>1.9348</PDBx:U11>
         <PDBx:U12>0.0082</PDBx:U12>
         <PDBx:U13>0.3587</PDBx:U13>
         <PDBx:U22>0.8318</PDBx:U22>
         <PDBx:U23>0.3060</PDBx:U23>
         <PDBx:U33>1.2571</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3092">
         <PDBx:U11>1.9410</PDBx:U11>
         <PDBx:U12>0.0251</PDBx:U12>
         <PDBx:U13>0.3202</PDBx:U13>
         <PDBx:U22>0.8649</PDBx:U22>
         <PDBx:U23>0.3200</PDBx:U23>
         <PDBx:U33>1.2907</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3093">
         <PDBx:U11>1.9807</PDBx:U11>
         <PDBx:U12>0.0327</PDBx:U12>
         <PDBx:U13>0.2817</PDBx:U13>
         <PDBx:U22>0.8975</PDBx:U22>
         <PDBx:U23>0.3518</PDBx:U23>
         <PDBx:U33>1.2974</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3094">
         <PDBx:U11>2.0220</PDBx:U11>
         <PDBx:U12>0.0105</PDBx:U12>
         <PDBx:U13>0.3484</PDBx:U13>
         <PDBx:U22>0.8811</PDBx:U22>
         <PDBx:U23>0.3445</PDBx:U23>
         <PDBx:U33>1.2918</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>467</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>167</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3095">
         <PDBx:U11>1.9024</PDBx:U11>
         <PDBx:U12>0.0315</PDBx:U12>
         <PDBx:U13>0.3287</PDBx:U13>
         <PDBx:U22>0.8576</PDBx:U22>
         <PDBx:U23>0.2968</PDBx:U23>
         <PDBx:U33>1.3143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3096">
         <PDBx:U11>1.8800</PDBx:U11>
         <PDBx:U12>0.0491</PDBx:U12>
         <PDBx:U13>0.2966</PDBx:U13>
         <PDBx:U22>0.8685</PDBx:U22>
         <PDBx:U23>0.3094</PDBx:U23>
         <PDBx:U33>1.3352</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3097">
         <PDBx:U11>1.9397</PDBx:U11>
         <PDBx:U12>0.0462</PDBx:U12>
         <PDBx:U13>0.2537</PDBx:U13>
         <PDBx:U22>0.9322</PDBx:U22>
         <PDBx:U23>0.3285</PDBx:U23>
         <PDBx:U33>1.3458</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3098">
         <PDBx:U11>2.0060</PDBx:U11>
         <PDBx:U12>0.0612</PDBx:U12>
         <PDBx:U13>0.2125</PDBx:U13>
         <PDBx:U22>0.9945</PDBx:U22>
         <PDBx:U23>0.3684</PDBx:U23>
         <PDBx:U33>1.4164</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3099">
         <PDBx:U11>1.7592</PDBx:U11>
         <PDBx:U12>0.0471</PDBx:U12>
         <PDBx:U13>0.3173</PDBx:U13>
         <PDBx:U22>0.7837</PDBx:U22>
         <PDBx:U23>0.2700</PDBx:U23>
         <PDBx:U33>1.2613</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3100">
         <PDBx:U11>1.7075</PDBx:U11>
         <PDBx:U12>0.0206</PDBx:U12>
         <PDBx:U13>0.3338</PDBx:U13>
         <PDBx:U22>0.7379</PDBx:U22>
         <PDBx:U23>0.2338</PDBx:U23>
         <PDBx:U33>1.1700</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>468</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>168</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3101">
         <PDBx:U11>1.8981</PDBx:U11>
         <PDBx:U12>0.0264</PDBx:U12>
         <PDBx:U13>0.2603</PDBx:U13>
         <PDBx:U22>0.8983</PDBx:U22>
         <PDBx:U23>0.2989</PDBx:U23>
         <PDBx:U33>1.2588</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3102">
         <PDBx:U11>1.9062</PDBx:U11>
         <PDBx:U12>0.0220</PDBx:U12>
         <PDBx:U13>0.2203</PDBx:U13>
         <PDBx:U22>0.9032</PDBx:U22>
         <PDBx:U23>0.3098</PDBx:U23>
         <PDBx:U33>1.2042</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3103">
         <PDBx:U11>1.8638</PDBx:U11>
         <PDBx:U12>0.0393</PDBx:U12>
         <PDBx:U13>0.1721</PDBx:U13>
         <PDBx:U22>0.8942</PDBx:U22>
         <PDBx:U23>0.3287</PDBx:U23>
         <PDBx:U33>1.2102</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3104">
         <PDBx:U11>1.8435</PDBx:U11>
         <PDBx:U12>0.0334</PDBx:U12>
         <PDBx:U13>0.1394</PDBx:U13>
         <PDBx:U22>0.8832</PDBx:U22>
         <PDBx:U23>0.3234</PDBx:U23>
         <PDBx:U33>1.1544</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3105">
         <PDBx:U11>1.9907</PDBx:U11>
         <PDBx:U12>0.0238</PDBx:U12>
         <PDBx:U13>0.2014</PDBx:U13>
         <PDBx:U22>0.9453</PDBx:U22>
         <PDBx:U23>0.3414</PDBx:U23>
         <PDBx:U33>1.2176</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>469</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>169</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3106">
         <PDBx:U11>1.2000</PDBx:U11>
         <PDBx:U12>0.2666</PDBx:U12>
         <PDBx:U13>0.0720</PDBx:U13>
         <PDBx:U22>0.6902</PDBx:U22>
         <PDBx:U23>0.1051</PDBx:U23>
         <PDBx:U33>0.9691</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3107">
         <PDBx:U11>1.1717</PDBx:U11>
         <PDBx:U12>0.2906</PDBx:U12>
         <PDBx:U13>0.0544</PDBx:U13>
         <PDBx:U22>0.7324</PDBx:U22>
         <PDBx:U23>0.1075</PDBx:U23>
         <PDBx:U33>0.9871</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3108">
         <PDBx:U11>1.1168</PDBx:U11>
         <PDBx:U12>0.2777</PDBx:U12>
         <PDBx:U13>0.0609</PDBx:U13>
         <PDBx:U22>0.7268</PDBx:U22>
         <PDBx:U23>0.0846</PDBx:U23>
         <PDBx:U33>0.9640</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3109">
         <PDBx:U11>1.0739</PDBx:U11>
         <PDBx:U12>0.2907</PDBx:U12>
         <PDBx:U13>0.0477</PDBx:U13>
         <PDBx:U22>0.7497</PDBx:U22>
         <PDBx:U23>0.0846</PDBx:U23>
         <PDBx:U33>0.9602</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3110">
         <PDBx:U11>1.2146</PDBx:U11>
         <PDBx:U12>0.3305</PDBx:U12>
         <PDBx:U13>0.0520</PDBx:U13>
         <PDBx:U22>0.7667</PDBx:U22>
         <PDBx:U23>0.1159</PDBx:U23>
         <PDBx:U33>1.0489</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>470</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>170</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3111">
         <PDBx:U11>1.1262</PDBx:U11>
         <PDBx:U12>0.2504</PDBx:U12>
         <PDBx:U13>0.0809</PDBx:U13>
         <PDBx:U22>0.7080</PDBx:U22>
         <PDBx:U23>0.0652</PDBx:U23>
         <PDBx:U33>0.9574</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3112">
         <PDBx:U11>1.0819</PDBx:U11>
         <PDBx:U12>0.2340</PDBx:U12>
         <PDBx:U13>0.0859</PDBx:U13>
         <PDBx:U22>0.7093</PDBx:U22>
         <PDBx:U23>0.0451</PDBx:U23>
         <PDBx:U33>0.9380</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3113">
         <PDBx:U11>0.9910</PDBx:U11>
         <PDBx:U12>0.2143</PDBx:U12>
         <PDBx:U13>0.0725</PDBx:U13>
         <PDBx:U22>0.6548</PDBx:U22>
         <PDBx:U23>0.0508</PDBx:U23>
         <PDBx:U33>0.8459</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3114">
         <PDBx:U11>0.9396</PDBx:U11>
         <PDBx:U12>0.2162</PDBx:U12>
         <PDBx:U13>0.0629</PDBx:U13>
         <PDBx:U22>0.6637</PDBx:U22>
         <PDBx:U23>0.0477</PDBx:U23>
         <PDBx:U33>0.8256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3115">
         <PDBx:U11>1.1190</PDBx:U11>
         <PDBx:U12>0.2088</PDBx:U12>
         <PDBx:U13>0.1091</PDBx:U13>
         <PDBx:U22>0.7094</PDBx:U22>
         <PDBx:U23>0.0223</PDBx:U23>
         <PDBx:U33>0.9589</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3116">
         <PDBx:U11>1.2226</PDBx:U11>
         <PDBx:U12>0.2243</PDBx:U12>
         <PDBx:U13>0.1245</PDBx:U13>
         <PDBx:U22>0.7683</PDBx:U22>
         <PDBx:U23>0.0137</PDBx:U23>
         <PDBx:U33>1.0584</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3117">
         <PDBx:U11>1.2181</PDBx:U11>
         <PDBx:U12>0.2555</PDBx:U12>
         <PDBx:U13>0.1222</PDBx:U13>
         <PDBx:U22>0.8032</PDBx:U22>
         <PDBx:U23>0.0074</PDBx:U23>
         <PDBx:U33>1.0945</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3118">
         <PDBx:U11>1.1763</PDBx:U11>
         <PDBx:U12>0.2566</PDBx:U12>
         <PDBx:U13>0.1138</PDBx:U13>
         <PDBx:U22>0.8282</PDBx:U22>
         <PDBx:U23>0.0025</PDBx:U23>
         <PDBx:U33>1.0858</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3119">
         <PDBx:U11>1.2674</PDBx:U11>
         <PDBx:U12>0.2787</PDBx:U12>
         <PDBx:U13>0.1302</PDBx:U13>
         <PDBx:U22>0.8164</PDBx:U22>
         <PDBx:U23>0.0068</PDBx:U23>
         <PDBx:U33>1.1430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>471</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>171</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3120">
         <PDBx:U11>0.9945</PDBx:U11>
         <PDBx:U12>0.1945</PDBx:U12>
         <PDBx:U13>0.0732</PDBx:U13>
         <PDBx:U22>0.6218</PDBx:U22>
         <PDBx:U23>0.0582</PDBx:U23>
         <PDBx:U33>0.8133</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3121">
         <PDBx:U11>0.9431</PDBx:U11>
         <PDBx:U12>0.1764</PDBx:U12>
         <PDBx:U13>0.0609</PDBx:U13>
         <PDBx:U22>0.5977</PDBx:U22>
         <PDBx:U23>0.0638</PDBx:U23>
         <PDBx:U33>0.7569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3122">
         <PDBx:U11>0.8785</PDBx:U11>
         <PDBx:U12>0.1968</PDBx:U12>
         <PDBx:U13>0.0360</PDBx:U13>
         <PDBx:U22>0.5859</PDBx:U22>
         <PDBx:U23>0.0796</PDBx:U23>
         <PDBx:U33>0.7159</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3123">
         <PDBx:U11>0.7349</PDBx:U11>
         <PDBx:U12>0.1881</PDBx:U12>
         <PDBx:U13>0.0249</PDBx:U13>
         <PDBx:U22>0.4907</PDBx:U22>
         <PDBx:U23>0.0781</PDBx:U23>
         <PDBx:U33>0.5903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3124">
         <PDBx:U11>1.0094</PDBx:U11>
         <PDBx:U12>0.1562</PDBx:U12>
         <PDBx:U13>0.0654</PDBx:U13>
         <PDBx:U22>0.6175</PDBx:U22>
         <PDBx:U23>0.0707</PDBx:U23>
         <PDBx:U33>0.7811</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3125">
         <PDBx:U11>1.0603</PDBx:U11>
         <PDBx:U12>0.1386</PDBx:U12>
         <PDBx:U13>0.0527</PDBx:U13>
         <PDBx:U22>0.6947</PDBx:U22>
         <PDBx:U23>0.0759</PDBx:U23>
         <PDBx:U33>0.8254</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3126">
         <PDBx:U11>1.1686</PDBx:U11>
         <PDBx:U12>0.1181</PDBx:U12>
         <PDBx:U13>0.0598</PDBx:U13>
         <PDBx:U22>0.7615</PDBx:U22>
         <PDBx:U23>0.0799</PDBx:U23>
         <PDBx:U33>0.8942</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3127">
         <PDBx:U11>1.1832</PDBx:U11>
         <PDBx:U12>0.1012</PDBx:U12>
         <PDBx:U13>0.0479</PDBx:U13>
         <PDBx:U22>0.8045</PDBx:U22>
         <PDBx:U23>0.0828</PDBx:U23>
         <PDBx:U33>0.9041</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3128">
         <PDBx:U11>1.1041</PDBx:U11>
         <PDBx:U12>0.0852</PDBx:U12>
         <PDBx:U13>0.0497</PDBx:U13>
         <PDBx:U22>0.7616</PDBx:U22>
         <PDBx:U23>0.0675</PDBx:U23>
         <PDBx:U33>0.8477</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>472</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>172</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3129">
         <PDBx:U11>0.9369</PDBx:U11>
         <PDBx:U12>0.2227</PDBx:U12>
         <PDBx:U13>0.0269</PDBx:U13>
         <PDBx:U22>0.6370</PDBx:U22>
         <PDBx:U23>0.0946</PDBx:U23>
         <PDBx:U33>0.7758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3130">
         <PDBx:U11>0.9071</PDBx:U11>
         <PDBx:U12>0.2404</PDBx:U12>
         <PDBx:U13>0.0019</PDBx:U13>
         <PDBx:U22>0.6630</PDBx:U22>
         <PDBx:U23>0.1089</PDBx:U23>
         <PDBx:U33>0.7717</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3131">
         <PDBx:U11>0.7618</PDBx:U11>
         <PDBx:U12>0.2511</PDBx:U12>
         <PDBx:U13>-0.0015</PDBx:U13>
         <PDBx:U22>0.5832</PDBx:U22>
         <PDBx:U23>0.0983</PDBx:U23>
         <PDBx:U33>0.6758</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3132">
         <PDBx:U11>0.6658</PDBx:U11>
         <PDBx:U12>0.2457</PDBx:U12>
         <PDBx:U13>-0.0187</PDBx:U13>
         <PDBx:U22>0.5477</PDBx:U22>
         <PDBx:U23>0.1008</PDBx:U23>
         <PDBx:U33>0.6037</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3133">
         <PDBx:U11>1.0207</PDBx:U11>
         <PDBx:U12>0.2670</PDBx:U12>
         <PDBx:U13>-0.0067</PDBx:U13>
         <PDBx:U22>0.7526</PDBx:U22>
         <PDBx:U23>0.1278</PDBx:U23>
         <PDBx:U33>0.8765</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3134">
         <PDBx:U11>1.1261</PDBx:U11>
         <PDBx:U12>0.2553</PDBx:U12>
         <PDBx:U13>-0.0061</PDBx:U13>
         <PDBx:U22>0.8019</PDBx:U22>
         <PDBx:U23>0.1415</PDBx:U23>
         <PDBx:U33>0.9332</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3135">
         <PDBx:U11>1.2547</PDBx:U11>
         <PDBx:U12>0.2728</PDBx:U12>
         <PDBx:U13>-0.0023</PDBx:U13>
         <PDBx:U22>0.8834</PDBx:U22>
         <PDBx:U23>0.1534</PDBx:U23>
         <PDBx:U33>1.0431</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3136">
         <PDBx:U11>1.1246</PDBx:U11>
         <PDBx:U12>0.2284</PDBx:U12>
         <PDBx:U13>-0.0085</PDBx:U13>
         <PDBx:U22>0.8031</PDBx:U22>
         <PDBx:U23>0.1401</PDBx:U23>
         <PDBx:U33>0.9124</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>473</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>173</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3137">
         <PDBx:U11>0.7169</PDBx:U11>
         <PDBx:U12>0.2631</PDBx:U12>
         <PDBx:U13>0.0159</PDBx:U13>
         <PDBx:U22>0.5267</PDBx:U22>
         <PDBx:U23>0.0852</PDBx:U23>
         <PDBx:U33>0.6455</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3138">
         <PDBx:U11>0.6711</PDBx:U11>
         <PDBx:U12>0.2703</PDBx:U12>
         <PDBx:U13>0.0173</PDBx:U13>
         <PDBx:U22>0.5419</PDBx:U22>
         <PDBx:U23>0.0725</PDBx:U23>
         <PDBx:U33>0.6454</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3139">
         <PDBx:U11>0.6192</PDBx:U11>
         <PDBx:U12>0.2439</PDBx:U12>
         <PDBx:U13>0.0175</PDBx:U13>
         <PDBx:U22>0.5279</PDBx:U22>
         <PDBx:U23>0.0619</PDBx:U23>
         <PDBx:U33>0.6025</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3140">
         <PDBx:U11>0.5727</PDBx:U11>
         <PDBx:U12>0.2421</PDBx:U12>
         <PDBx:U13>0.0081</PDBx:U13>
         <PDBx:U22>0.5484</PDBx:U22>
         <PDBx:U23>0.0594</PDBx:U23>
         <PDBx:U33>0.5917</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3141">
         <PDBx:U11>0.6505</PDBx:U11>
         <PDBx:U12>0.2818</PDBx:U12>
         <PDBx:U13>0.0397</PDBx:U13>
         <PDBx:U22>0.4935</PDBx:U22>
         <PDBx:U23>0.0561</PDBx:U23>
         <PDBx:U33>0.6315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3142">
         <PDBx:U11>0.5941</PDBx:U11>
         <PDBx:U12>0.2817</PDBx:U12>
         <PDBx:U13>0.0461</PDBx:U13>
         <PDBx:U22>0.4961</PDBx:U22>
         <PDBx:U23>0.0390</PDBx:U23>
         <PDBx:U33>0.6163</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3143">
         <PDBx:U11>0.5507</PDBx:U11>
         <PDBx:U12>0.3031</PDBx:U12>
         <PDBx:U13>0.0385</PDBx:U13>
         <PDBx:U22>0.5082</PDBx:U22>
         <PDBx:U23>0.0408</PDBx:U23>
         <PDBx:U33>0.6152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3144">
         <PDBx:U11>0.5843</PDBx:U11>
         <PDBx:U12>0.2605</PDBx:U12>
         <PDBx:U13>0.0597</PDBx:U13>
         <PDBx:U22>0.5011</PDBx:U22>
         <PDBx:U23>0.0198</PDBx:U23>
         <PDBx:U33>0.6117</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3145">
         <PDBx:U11>0.5163</PDBx:U11>
         <PDBx:U12>0.2936</PDBx:U12>
         <PDBx:U13>0.0488</PDBx:U13>
         <PDBx:U22>0.5181</PDBx:U22>
         <PDBx:U23>0.0232</PDBx:U23>
         <PDBx:U33>0.6085</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3146">
         <PDBx:U11>0.5903</PDBx:U11>
         <PDBx:U12>0.2682</PDBx:U12>
         <PDBx:U13>0.0611</PDBx:U13>
         <PDBx:U22>0.5684</PDBx:U22>
         <PDBx:U23>0.0108</PDBx:U23>
         <PDBx:U33>0.6597</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>474</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>174</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3147">
         <PDBx:U11>0.6102</PDBx:U11>
         <PDBx:U12>0.2216</PDBx:U12>
         <PDBx:U13>0.0290</PDBx:U13>
         <PDBx:U22>0.4759</PDBx:U22>
         <PDBx:U23>0.0555</PDBx:U23>
         <PDBx:U33>0.5615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3148">
         <PDBx:U11>0.6034</PDBx:U11>
         <PDBx:U12>0.1984</PDBx:U12>
         <PDBx:U13>0.0302</PDBx:U13>
         <PDBx:U22>0.4978</PDBx:U22>
         <PDBx:U23>0.0463</PDBx:U23>
         <PDBx:U33>0.5608</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3149">
         <PDBx:U11>0.5586</PDBx:U11>
         <PDBx:U12>0.1898</PDBx:U12>
         <PDBx:U13>0.0074</PDBx:U13>
         <PDBx:U22>0.4935</PDBx:U22>
         <PDBx:U23>0.0592</PDBx:U23>
         <PDBx:U33>0.5215</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3150">
         <PDBx:U11>0.5112</PDBx:U11>
         <PDBx:U12>0.1786</PDBx:U12>
         <PDBx:U13>0.0013</PDBx:U13>
         <PDBx:U22>0.4999</PDBx:U22>
         <PDBx:U23>0.0547</PDBx:U23>
         <PDBx:U33>0.4998</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3151">
         <PDBx:U11>0.6608</PDBx:U11>
         <PDBx:U12>0.1751</PDBx:U12>
         <PDBx:U13>0.0475</PDBx:U13>
         <PDBx:U22>0.4987</PDBx:U22>
         <PDBx:U23>0.0359</PDBx:U23>
         <PDBx:U33>0.5832</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3152">
         <PDBx:U11>0.6953</PDBx:U11>
         <PDBx:U12>0.1732</PDBx:U12>
         <PDBx:U13>0.0693</PDBx:U13>
         <PDBx:U22>0.5067</PDBx:U22>
         <PDBx:U23>0.0170</PDBx:U23>
         <PDBx:U33>0.6171</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3153">
         <PDBx:U11>0.6066</PDBx:U11>
         <PDBx:U12>0.1531</PDBx:U12>
         <PDBx:U13>0.0454</PDBx:U13>
         <PDBx:U22>0.4727</PDBx:U22>
         <PDBx:U23>0.0301</PDBx:U23>
         <PDBx:U33>0.5342</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3154">
         <PDBx:U11>0.7585</PDBx:U11>
         <PDBx:U12>0.1451</PDBx:U12>
         <PDBx:U13>0.0849</PDBx:U13>
         <PDBx:U22>0.5183</PDBx:U22>
         <PDBx:U23>0.0058</PDBx:U23>
         <PDBx:U33>0.6476</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>475</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>175</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3155">
         <PDBx:U11>0.6071</PDBx:U11>
         <PDBx:U12>0.1914</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.5170</PDBx:U22>
         <PDBx:U23>0.0741</PDBx:U23>
         <PDBx:U33>0.5451</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3156">
         <PDBx:U11>0.5962</PDBx:U11>
         <PDBx:U12>0.1779</PDBx:U12>
         <PDBx:U13>-0.0260</PDBx:U13>
         <PDBx:U22>0.5385</PDBx:U22>
         <PDBx:U23>0.0834</PDBx:U23>
         <PDBx:U33>0.5334</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3157">
         <PDBx:U11>0.5238</PDBx:U11>
         <PDBx:U12>0.1844</PDBx:U12>
         <PDBx:U13>-0.0433</PDBx:U13>
         <PDBx:U22>0.5374</PDBx:U22>
         <PDBx:U23>0.0855</PDBx:U23>
         <PDBx:U33>0.5029</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3158">
         <PDBx:U11>0.5112</PDBx:U11>
         <PDBx:U12>0.1652</PDBx:U12>
         <PDBx:U13>-0.0554</PDBx:U13>
         <PDBx:U22>0.5660</PDBx:U22>
         <PDBx:U23>0.0836</PDBx:U23>
         <PDBx:U33>0.5030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3159">
         <PDBx:U11>0.7206</PDBx:U11>
         <PDBx:U12>0.1770</PDBx:U12>
         <PDBx:U13>-0.0332</PDBx:U13>
         <PDBx:U22>0.6203</PDBx:U22>
         <PDBx:U23>0.0974</PDBx:U23>
         <PDBx:U33>0.6200</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3160">
         <PDBx:U11>0.7616</PDBx:U11>
         <PDBx:U12>0.1579</PDBx:U12>
         <PDBx:U13>-0.0174</PDBx:U13>
         <PDBx:U22>0.6014</PDBx:U22>
         <PDBx:U23>0.0935</PDBx:U23>
         <PDBx:U33>0.6199</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3161">
         <PDBx:U11>0.8175</PDBx:U11>
         <PDBx:U12>0.1588</PDBx:U12>
         <PDBx:U13>-0.0113</PDBx:U13>
         <PDBx:U22>0.6030</PDBx:U22>
         <PDBx:U23>0.1016</PDBx:U23>
         <PDBx:U33>0.6405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3162">
         <PDBx:U11>0.7265</PDBx:U11>
         <PDBx:U12>0.1354</PDBx:U12>
         <PDBx:U13>-0.0059</PDBx:U13>
         <PDBx:U22>0.5555</PDBx:U22>
         <PDBx:U23>0.0816</PDBx:U23>
         <PDBx:U33>0.5757</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3163">
         <PDBx:U11>0.8424</PDBx:U11>
         <PDBx:U12>0.1350</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.5906</PDBx:U22>
         <PDBx:U23>0.0927</PDBx:U23>
         <PDBx:U33>0.6387</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3164">
         <PDBx:U11>0.7611</PDBx:U11>
         <PDBx:U12>0.1208</PDBx:U12>
         <PDBx:U13>0.0076</PDBx:U13>
         <PDBx:U22>0.5347</PDBx:U22>
         <PDBx:U23>0.0804</PDBx:U23>
         <PDBx:U33>0.5733</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>476</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>176</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3165">
         <PDBx:U11>0.4868</PDBx:U11>
         <PDBx:U12>0.2092</PDBx:U12>
         <PDBx:U13>-0.0430</PDBx:U13>
         <PDBx:U22>0.5119</PDBx:U22>
         <PDBx:U23>0.0881</PDBx:U23>
         <PDBx:U33>0.4868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3166">
         <PDBx:U11>0.4666</PDBx:U11>
         <PDBx:U12>0.2153</PDBx:U12>
         <PDBx:U13>-0.0566</PDBx:U13>
         <PDBx:U22>0.5593</PDBx:U22>
         <PDBx:U23>0.0885</PDBx:U23>
         <PDBx:U33>0.5088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3167">
         <PDBx:U11>0.4029</PDBx:U11>
         <PDBx:U12>0.2003</PDBx:U12>
         <PDBx:U13>-0.0479</PDBx:U13>
         <PDBx:U22>0.5422</PDBx:U22>
         <PDBx:U23>0.0734</PDBx:U23>
         <PDBx:U33>0.4769</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3168">
         <PDBx:U11>0.3744</PDBx:U11>
         <PDBx:U12>0.1845</PDBx:U12>
         <PDBx:U13>-0.0593</PDBx:U13>
         <PDBx:U22>0.5655</PDBx:U22>
         <PDBx:U23>0.0716</PDBx:U23>
         <PDBx:U33>0.4719</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3169">
         <PDBx:U11>0.5415</PDBx:U11>
         <PDBx:U12>0.2479</PDBx:U12>
         <PDBx:U13>-0.0555</PDBx:U13>
         <PDBx:U22>0.6325</PDBx:U22>
         <PDBx:U23>0.0939</PDBx:U23>
         <PDBx:U33>0.5996</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>477</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>177</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3170">
         <PDBx:U11>0.4360</PDBx:U11>
         <PDBx:U12>0.2028</PDBx:U12>
         <PDBx:U13>-0.0265</PDBx:U13>
         <PDBx:U22>0.5535</PDBx:U22>
         <PDBx:U23>0.0621</PDBx:U23>
         <PDBx:U33>0.5080</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3171">
         <PDBx:U11>0.4204</PDBx:U11>
         <PDBx:U12>0.1862</PDBx:U12>
         <PDBx:U13>-0.0164</PDBx:U13>
         <PDBx:U22>0.5768</PDBx:U22>
         <PDBx:U23>0.0484</PDBx:U23>
         <PDBx:U33>0.5164</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3172">
         <PDBx:U11>0.3797</PDBx:U11>
         <PDBx:U12>0.1564</PDBx:U12>
         <PDBx:U13>-0.0236</PDBx:U13>
         <PDBx:U22>0.5477</PDBx:U22>
         <PDBx:U23>0.0484</PDBx:U23>
         <PDBx:U33>0.4672</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3173">
         <PDBx:U11>0.3659</PDBx:U11>
         <PDBx:U12>0.1369</PDBx:U12>
         <PDBx:U13>-0.0267</PDBx:U13>
         <PDBx:U22>0.5778</PDBx:U22>
         <PDBx:U23>0.0439</PDBx:U23>
         <PDBx:U33>0.4754</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3174">
         <PDBx:U11>0.3754</PDBx:U11>
         <PDBx:U12>0.1914</PDBx:U12>
         <PDBx:U13>0.0080</PDBx:U13>
         <PDBx:U22>0.4996</PDBx:U22>
         <PDBx:U23>0.0347</PDBx:U23>
         <PDBx:U33>0.4634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3175">
         <PDBx:U11>0.3416</PDBx:U11>
         <PDBx:U12>0.1701</PDBx:U12>
         <PDBx:U13>0.0173</PDBx:U13>
         <PDBx:U22>0.5061</PDBx:U22>
         <PDBx:U23>0.0219</PDBx:U23>
         <PDBx:U33>0.4490</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3176">
         <PDBx:U11>0.4342</PDBx:U11>
         <PDBx:U12>0.2191</PDBx:U12>
         <PDBx:U13>0.0170</PDBx:U13>
         <PDBx:U22>0.5429</PDBx:U22>
         <PDBx:U23>0.0319</PDBx:U23>
         <PDBx:U33>0.5313</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>478</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>178</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3177">
         <PDBx:U11>0.3789</PDBx:U11>
         <PDBx:U12>0.1516</PDBx:U12>
         <PDBx:U13>-0.0247</PDBx:U13>
         <PDBx:U22>0.5014</PDBx:U22>
         <PDBx:U23>0.0533</PDBx:U23>
         <PDBx:U33>0.4320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3178">
         <PDBx:U11>0.2908</PDBx:U11>
         <PDBx:U12>0.1251</PDBx:U12>
         <PDBx:U13>-0.0319</PDBx:U13>
         <PDBx:U22>0.4186</PDBx:U22>
         <PDBx:U23>0.0535</PDBx:U23>
         <PDBx:U33>0.3338</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3179">
         <PDBx:U11>0.3262</PDBx:U11>
         <PDBx:U12>0.1105</PDBx:U12>
         <PDBx:U13>-0.0514</PDBx:U13>
         <PDBx:U22>0.4875</PDBx:U22>
         <PDBx:U23>0.0579</PDBx:U23>
         <PDBx:U33>0.3797</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3180">
         <PDBx:U11>0.2756</PDBx:U11>
         <PDBx:U12>0.0861</PDBx:U12>
         <PDBx:U13>-0.0542</PDBx:U13>
         <PDBx:U22>0.4604</PDBx:U22>
         <PDBx:U23>0.0527</PDBx:U23>
         <PDBx:U33>0.3392</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3181">
         <PDBx:U11>0.3380</PDBx:U11>
         <PDBx:U12>0.1209</PDBx:U12>
         <PDBx:U13>-0.0279</PDBx:U13>
         <PDBx:U22>0.4035</PDBx:U22>
         <PDBx:U23>0.0568</PDBx:U23>
         <PDBx:U33>0.3377</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3182">
         <PDBx:U11>0.3917</PDBx:U11>
         <PDBx:U12>0.1104</PDBx:U12>
         <PDBx:U13>-0.0055</PDBx:U13>
         <PDBx:U22>0.4177</PDBx:U22>
         <PDBx:U23>0.0433</PDBx:U23>
         <PDBx:U33>0.3777</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3183">
         <PDBx:U11>0.4153</PDBx:U11>
         <PDBx:U12>0.1010</PDBx:U12>
         <PDBx:U13>0.0001</PDBx:U13>
         <PDBx:U22>0.3796</PDBx:U22>
         <PDBx:U23>0.0448</PDBx:U23>
         <PDBx:U33>0.3597</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3184">
         <PDBx:U11>0.3392</PDBx:U11>
         <PDBx:U12>0.0858</PDBx:U12>
         <PDBx:U13>-0.0014</PDBx:U13>
         <PDBx:U22>0.3974</PDBx:U22>
         <PDBx:U23>0.0328</PDBx:U23>
         <PDBx:U33>0.3434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>479</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>179</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3185">
         <PDBx:U11>0.2936</PDBx:U11>
         <PDBx:U12>0.1249</PDBx:U12>
         <PDBx:U13>-0.0639</PDBx:U13>
         <PDBx:U22>0.4524</PDBx:U22>
         <PDBx:U23>0.0668</PDBx:U23>
         <PDBx:U33>0.3427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3186">
         <PDBx:U11>0.3482</PDBx:U11>
         <PDBx:U12>0.1132</PDBx:U12>
         <PDBx:U13>-0.0830</PDBx:U13>
         <PDBx:U22>0.5394</PDBx:U22>
         <PDBx:U23>0.0693</PDBx:U23>
         <PDBx:U33>0.4068</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3187">
         <PDBx:U11>0.3470</PDBx:U11>
         <PDBx:U12>0.1046</PDBx:U12>
         <PDBx:U13>-0.0819</PDBx:U13>
         <PDBx:U22>0.5927</PDBx:U22>
         <PDBx:U23>0.0616</PDBx:U23>
         <PDBx:U33>0.4453</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3188">
         <PDBx:U11>0.4038</PDBx:U11>
         <PDBx:U12>0.0826</PDBx:U12>
         <PDBx:U13>-0.0902</PDBx:U13>
         <PDBx:U22>0.6723</PDBx:U22>
         <PDBx:U23>0.0577</PDBx:U23>
         <PDBx:U33>0.5087</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3189">
         <PDBx:U11>0.4434</PDBx:U11>
         <PDBx:U12>0.1338</PDBx:U12>
         <PDBx:U13>-0.0972</PDBx:U13>
         <PDBx:U22>0.6275</PDBx:U22>
         <PDBx:U23>0.0817</PDBx:U23>
         <PDBx:U33>0.4930</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3190">
         <PDBx:U11>0.5331</PDBx:U11>
         <PDBx:U12>0.1316</PDBx:U12>
         <PDBx:U13>-0.1017</PDBx:U13>
         <PDBx:U22>0.6645</PDBx:U22>
         <PDBx:U23>0.0908</PDBx:U23>
         <PDBx:U33>0.5366</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3191">
         <PDBx:U11>0.5340</PDBx:U11>
         <PDBx:U12>0.1105</PDBx:U12>
         <PDBx:U13>-0.0975</PDBx:U13>
         <PDBx:U22>0.6434</PDBx:U22>
         <PDBx:U23>0.0858</PDBx:U23>
         <PDBx:U33>0.5152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3192">
         <PDBx:U11>0.6132</PDBx:U11>
         <PDBx:U12>0.1504</PDBx:U12>
         <PDBx:U13>-0.1087</PDBx:U13>
         <PDBx:U22>0.7248</PDBx:U22>
         <PDBx:U23>0.1034</PDBx:U23>
         <PDBx:U33>0.6020</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>480</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>180</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3193">
         <PDBx:U11>0.3251</PDBx:U11>
         <PDBx:U12>0.1213</PDBx:U12>
         <PDBx:U13>-0.0696</PDBx:U13>
         <PDBx:U22>0.5872</PDBx:U22>
         <PDBx:U23>0.0584</PDBx:U23>
         <PDBx:U33>0.4464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3194">
         <PDBx:U11>0.3371</PDBx:U11>
         <PDBx:U12>0.1133</PDBx:U12>
         <PDBx:U13>-0.0657</PDBx:U13>
         <PDBx:U22>0.6488</PDBx:U22>
         <PDBx:U23>0.0515</PDBx:U23>
         <PDBx:U33>0.4934</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3195">
         <PDBx:U11>0.2739</PDBx:U11>
         <PDBx:U12>0.0845</PDBx:U12>
         <PDBx:U13>-0.0556</PDBx:U13>
         <PDBx:U22>0.5878</PDBx:U22>
         <PDBx:U23>0.0435</PDBx:U23>
         <PDBx:U33>0.4289</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3196">
         <PDBx:U11>0.2512</PDBx:U11>
         <PDBx:U12>0.0664</PDBx:U12>
         <PDBx:U13>-0.0573</PDBx:U13>
         <PDBx:U22>0.5962</PDBx:U22>
         <PDBx:U23>0.0402</PDBx:U23>
         <PDBx:U33>0.4227</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3197">
         <PDBx:U11>0.4021</PDBx:U11>
         <PDBx:U12>0.1389</PDBx:U12>
         <PDBx:U13>-0.0532</PDBx:U13>
         <PDBx:U22>0.7264</PDBx:U22>
         <PDBx:U23>0.0487</PDBx:U23>
         <PDBx:U33>0.5801</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3198">
         <PDBx:U11>0.5516</PDBx:U11>
         <PDBx:U12>0.1691</PDBx:U12>
         <PDBx:U13>-0.0636</PDBx:U13>
         <PDBx:U22>0.8808</PDBx:U22>
         <PDBx:U23>0.0575</PDBx:U23>
         <PDBx:U33>0.7386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3199">
         <PDBx:U11>0.6425</PDBx:U11>
         <PDBx:U12>0.1930</PDBx:U12>
         <PDBx:U13>-0.0495</PDBx:U13>
         <PDBx:U22>0.9886</PDBx:U22>
         <PDBx:U23>0.0521</PDBx:U23>
         <PDBx:U33>0.8569</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3200">
         <PDBx:U11>0.6640</PDBx:U11>
         <PDBx:U12>0.1787</PDBx:U12>
         <PDBx:U13>-0.0449</PDBx:U13>
         <PDBx:U22>1.0685</PDBx:U22>
         <PDBx:U23>0.0436</PDBx:U23>
         <PDBx:U33>0.9143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3201">
         <PDBx:U11>0.6859</PDBx:U11>
         <PDBx:U12>0.1755</PDBx:U12>
         <PDBx:U13>-0.0642</PDBx:U13>
         <PDBx:U22>1.1385</PDBx:U22>
         <PDBx:U23>0.0492</PDBx:U23>
         <PDBx:U33>0.9595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>481</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>181</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3202">
         <PDBx:U11>0.2271</PDBx:U11>
         <PDBx:U12>0.0806</PDBx:U12>
         <PDBx:U13>-0.0449</PDBx:U13>
         <PDBx:U22>0.5065</PDBx:U22>
         <PDBx:U23>0.0413</PDBx:U23>
         <PDBx:U33>0.3615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3203">
         <PDBx:U11>0.1950</PDBx:U11>
         <PDBx:U12>0.0550</PDBx:U12>
         <PDBx:U13>-0.0367</PDBx:U13>
         <PDBx:U22>0.4704</PDBx:U22>
         <PDBx:U23>0.0362</PDBx:U23>
         <PDBx:U33>0.3242</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3204">
         <PDBx:U11>0.1656</PDBx:U11>
         <PDBx:U12>0.0326</PDBx:U12>
         <PDBx:U13>-0.0481</PDBx:U13>
         <PDBx:U22>0.4344</PDBx:U22>
         <PDBx:U23>0.0378</PDBx:U23>
         <PDBx:U33>0.2839</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3205">
         <PDBx:U11>0.2202</PDBx:U11>
         <PDBx:U12>0.0119</PDBx:U12>
         <PDBx:U13>-0.0451</PDBx:U13>
         <PDBx:U22>0.4967</PDBx:U22>
         <PDBx:U23>0.0351</PDBx:U23>
         <PDBx:U33>0.3424</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3206">
         <PDBx:U11>0.2125</PDBx:U11>
         <PDBx:U12>0.0568</PDBx:U12>
         <PDBx:U13>-0.0247</PDBx:U13>
         <PDBx:U22>0.4562</PDBx:U22>
         <PDBx:U23>0.0336</PDBx:U23>
         <PDBx:U33>0.3234</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3207">
         <PDBx:U11>0.2445</PDBx:U11>
         <PDBx:U12>0.0782</PDBx:U12>
         <PDBx:U13>-0.0107</PDBx:U13>
         <PDBx:U22>0.4897</PDBx:U22>
         <PDBx:U23>0.0283</PDBx:U23>
         <PDBx:U33>0.3634</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3208">
         <PDBx:U11>0.2609</PDBx:U11>
         <PDBx:U12>0.0314</PDBx:U12>
         <PDBx:U13>-0.0185</PDBx:U13>
         <PDBx:U22>0.4992</PDBx:U22>
         <PDBx:U23>0.0304</PDBx:U23>
         <PDBx:U33>0.3653</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3209">
         <PDBx:U11>0.2866</PDBx:U11>
         <PDBx:U12>0.0802</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.5018</PDBx:U22>
         <PDBx:U23>0.0226</PDBx:U23>
         <PDBx:U33>0.3878</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>482</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>182</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3210">
         <PDBx:U11>0.2038</PDBx:U11>
         <PDBx:U12>0.0376</PDBx:U12>
         <PDBx:U13>-0.0604</PDBx:U13>
         <PDBx:U22>0.4537</PDBx:U22>
         <PDBx:U23>0.0421</PDBx:U23>
         <PDBx:U33>0.3048</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3211">
         <PDBx:U11>0.2148</PDBx:U11>
         <PDBx:U12>0.0180</PDBx:U12>
         <PDBx:U13>-0.0713</PDBx:U13>
         <PDBx:U22>0.4577</PDBx:U22>
         <PDBx:U23>0.0411</PDBx:U23>
         <PDBx:U33>0.3031</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3212">
         <PDBx:U11>0.2832</PDBx:U11>
         <PDBx:U12>0.0091</PDBx:U12>
         <PDBx:U13>-0.0792</PDBx:U13>
         <PDBx:U22>0.5657</PDBx:U22>
         <PDBx:U23>0.0393</PDBx:U23>
         <PDBx:U33>0.3935</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3213">
         <PDBx:U11>0.2408</PDBx:U11>
         <PDBx:U12>-0.0136</PDBx:U12>
         <PDBx:U13>-0.0788</PDBx:U13>
         <PDBx:U22>0.5267</PDBx:U22>
         <PDBx:U23>0.0352</PDBx:U23>
         <PDBx:U33>0.3514</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3214">
         <PDBx:U11>0.3138</PDBx:U11>
         <PDBx:U12>0.0262</PDBx:U12>
         <PDBx:U13>-0.0835</PDBx:U13>
         <PDBx:U22>0.5297</PDBx:U22>
         <PDBx:U23>0.0459</PDBx:U23>
         <PDBx:U33>0.3744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3215">
         <PDBx:U11>0.3393</PDBx:U11>
         <PDBx:U12>0.0335</PDBx:U12>
         <PDBx:U13>-0.0750</PDBx:U13>
         <PDBx:U22>0.5182</PDBx:U22>
         <PDBx:U23>0.0482</PDBx:U23>
         <PDBx:U33>0.3780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3216">
         <PDBx:U11>0.2588</PDBx:U11>
         <PDBx:U12>0.0046</PDBx:U12>
         <PDBx:U13>-0.0926</PDBx:U13>
         <PDBx:U22>0.4671</PDBx:U22>
         <PDBx:U23>0.0416</PDBx:U23>
         <PDBx:U33>0.3034</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>483</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>183</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3217">
         <PDBx:U11>0.2556</PDBx:U11>
         <PDBx:U12>0.0277</PDBx:U12>
         <PDBx:U13>-0.0859</PDBx:U13>
         <PDBx:U22>0.5679</PDBx:U22>
         <PDBx:U23>0.0426</PDBx:U23>
         <PDBx:U33>0.3848</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3218">
         <PDBx:U11>0.2766</PDBx:U11>
         <PDBx:U12>0.0210</PDBx:U12>
         <PDBx:U13>-0.0932</PDBx:U13>
         <PDBx:U22>0.6357</PDBx:U22>
         <PDBx:U23>0.0408</PDBx:U23>
         <PDBx:U33>0.4323</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3219">
         <PDBx:U11>0.2840</PDBx:U11>
         <PDBx:U12>0.0026</PDBx:U12>
         <PDBx:U13>-0.0793</PDBx:U13>
         <PDBx:U22>0.6592</PDBx:U22>
         <PDBx:U23>0.0355</PDBx:U23>
         <PDBx:U33>0.4550</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3220">
         <PDBx:U11>0.2708</PDBx:U11>
         <PDBx:U12>-0.0184</PDBx:U12>
         <PDBx:U13>-0.0826</PDBx:U13>
         <PDBx:U22>0.6661</PDBx:U22>
         <PDBx:U23>0.0323</PDBx:U23>
         <PDBx:U33>0.4499</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3221">
         <PDBx:U11>0.2644</PDBx:U11>
         <PDBx:U12>0.0485</PDBx:U12>
         <PDBx:U13>-0.0987</PDBx:U13>
         <PDBx:U22>0.6551</PDBx:U22>
         <PDBx:U23>0.0456</PDBx:U23>
         <PDBx:U33>0.4434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3222">
         <PDBx:U11>0.3300</PDBx:U11>
         <PDBx:U12>0.0671</PDBx:U12>
         <PDBx:U13>-0.1154</PDBx:U13>
         <PDBx:U22>0.7052</PDBx:U22>
         <PDBx:U23>0.0541</PDBx:U23>
         <PDBx:U33>0.4917</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3223">
         <PDBx:U11>0.3464</PDBx:U11>
         <PDBx:U12>0.0538</PDBx:U12>
         <PDBx:U13>-0.1261</PDBx:U13>
         <PDBx:U22>0.7000</PDBx:U22>
         <PDBx:U23>0.0544</PDBx:U23>
         <PDBx:U33>0.4816</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3224">
         <PDBx:U11>0.3858</PDBx:U11>
         <PDBx:U12>0.0954</PDBx:U12>
         <PDBx:U13>-0.1171</PDBx:U13>
         <PDBx:U22>0.7678</PDBx:U22>
         <PDBx:U23>0.0608</PDBx:U23>
         <PDBx:U33>0.5581</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>484</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>184</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3225">
         <PDBx:U11>0.2205</PDBx:U11>
         <PDBx:U12>0.0097</PDBx:U12>
         <PDBx:U13>-0.0636</PDBx:U13>
         <PDBx:U22>0.5850</PDBx:U22>
         <PDBx:U23>0.0348</PDBx:U23>
         <PDBx:U33>0.3924</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3226">
         <PDBx:U11>0.2107</PDBx:U11>
         <PDBx:U12>-0.0056</PDBx:U12>
         <PDBx:U13>-0.0500</PDBx:U13>
         <PDBx:U22>0.5862</PDBx:U22>
         <PDBx:U23>0.0316</PDBx:U23>
         <PDBx:U33>0.3912</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3227">
         <PDBx:U11>0.2140</PDBx:U11>
         <PDBx:U12>-0.0311</PDBx:U12>
         <PDBx:U13>-0.0478</PDBx:U13>
         <PDBx:U22>0.5612</PDBx:U22>
         <PDBx:U23>0.0313</PDBx:U23>
         <PDBx:U33>0.3744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3228">
         <PDBx:U11>0.2123</PDBx:U11>
         <PDBx:U12>-0.0502</PDBx:U12>
         <PDBx:U13>-0.0448</PDBx:U13>
         <PDBx:U22>0.5741</PDBx:U22>
         <PDBx:U23>0.0303</PDBx:U23>
         <PDBx:U33>0.3800</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3229">
         <PDBx:U11>0.2455</PDBx:U11>
         <PDBx:U12>0.0079</PDBx:U12>
         <PDBx:U13>-0.0347</PDBx:U13>
         <PDBx:U22>0.6121</PDBx:U22>
         <PDBx:U23>0.0301</PDBx:U23>
         <PDBx:U33>0.4253</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3230">
         <PDBx:U11>0.2489</PDBx:U11>
         <PDBx:U12>0.0332</PDBx:U12>
         <PDBx:U13>-0.0345</PDBx:U13>
         <PDBx:U22>0.6407</PDBx:U22>
         <PDBx:U23>0.0296</PDBx:U23>
         <PDBx:U33>0.4495</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3231">
         <PDBx:U11>0.1891</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>-0.0221</PDBx:U13>
         <PDBx:U22>0.5654</PDBx:U22>
         <PDBx:U23>0.0280</PDBx:U23>
         <PDBx:U33>0.3723</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>485</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>185</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3232">
         <PDBx:U11>0.2186</PDBx:U11>
         <PDBx:U12>-0.0310</PDBx:U12>
         <PDBx:U13>-0.0488</PDBx:U13>
         <PDBx:U22>0.5252</PDBx:U22>
         <PDBx:U23>0.0324</PDBx:U23>
         <PDBx:U33>0.3545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3233">
         <PDBx:U11>0.1968</PDBx:U11>
         <PDBx:U12>-0.0515</PDBx:U12>
         <PDBx:U13>-0.0469</PDBx:U13>
         <PDBx:U22>0.4737</PDBx:U22>
         <PDBx:U23>0.0323</PDBx:U23>
         <PDBx:U33>0.3143</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3234">
         <PDBx:U11>0.2215</PDBx:U11>
         <PDBx:U12>-0.0702</PDBx:U12>
         <PDBx:U13>-0.0566</PDBx:U13>
         <PDBx:U22>0.5095</PDBx:U22>
         <PDBx:U23>0.0298</PDBx:U23>
         <PDBx:U33>0.3415</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3235">
         <PDBx:U11>0.2333</PDBx:U11>
         <PDBx:U12>-0.0900</PDBx:U12>
         <PDBx:U13>-0.0524</PDBx:U13>
         <PDBx:U22>0.5186</PDBx:U22>
         <PDBx:U23>0.0293</PDBx:U23>
         <PDBx:U33>0.3529</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3236">
         <PDBx:U11>0.1942</PDBx:U11>
         <PDBx:U12>-0.0464</PDBx:U12>
         <PDBx:U13>-0.0472</PDBx:U13>
         <PDBx:U22>0.4316</PDBx:U22>
         <PDBx:U23>0.0330</PDBx:U23>
         <PDBx:U33>0.2888</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3237">
         <PDBx:U11>0.2111</PDBx:U11>
         <PDBx:U12>-0.0390</PDBx:U12>
         <PDBx:U13>-0.0355</PDBx:U13>
         <PDBx:U22>0.4290</PDBx:U22>
         <PDBx:U23>0.0344</PDBx:U23>
         <PDBx:U33>0.2977</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3238">
         <PDBx:U11>0.2133</PDBx:U11>
         <PDBx:U12>-0.0331</PDBx:U12>
         <PDBx:U13>-0.0372</PDBx:U13>
         <PDBx:U22>0.4011</PDBx:U22>
         <PDBx:U23>0.0343</PDBx:U23>
         <PDBx:U33>0.2821</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3239">
         <PDBx:U11>0.2325</PDBx:U11>
         <PDBx:U12>-0.0535</PDBx:U12>
         <PDBx:U13>-0.0278</PDBx:U13>
         <PDBx:U22>0.4402</PDBx:U22>
         <PDBx:U23>0.0364</PDBx:U23>
         <PDBx:U33>0.3144</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>486</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>186</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3240">
         <PDBx:U11>0.2738</PDBx:U11>
         <PDBx:U12>-0.0642</PDBx:U12>
         <PDBx:U13>-0.0702</PDBx:U13>
         <PDBx:U22>0.5732</PDBx:U22>
         <PDBx:U23>0.0283</PDBx:U23>
         <PDBx:U33>0.3944</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3241">
         <PDBx:U11>0.2657</PDBx:U11>
         <PDBx:U12>-0.0823</PDBx:U12>
         <PDBx:U13>-0.0813</PDBx:U13>
         <PDBx:U22>0.5798</PDBx:U22>
         <PDBx:U23>0.0240</PDBx:U23>
         <PDBx:U33>0.3875</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3242">
         <PDBx:U11>0.2534</PDBx:U11>
         <PDBx:U12>-0.0943</PDBx:U12>
         <PDBx:U13>-0.0793</PDBx:U13>
         <PDBx:U22>0.6097</PDBx:U22>
         <PDBx:U23>0.0225</PDBx:U23>
         <PDBx:U33>0.4015</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3243">
         <PDBx:U11>0.2299</PDBx:U11>
         <PDBx:U12>-0.1188</PDBx:U12>
         <PDBx:U13>-0.0802</PDBx:U13>
         <PDBx:U22>0.5882</PDBx:U22>
         <PDBx:U23>0.0185</PDBx:U23>
         <PDBx:U33>0.3770</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3244">
         <PDBx:U11>0.3012</PDBx:U11>
         <PDBx:U12>-0.0703</PDBx:U12>
         <PDBx:U13>-0.0983</PDBx:U13>
         <PDBx:U22>0.6268</PDBx:U22>
         <PDBx:U23>0.0238</PDBx:U23>
         <PDBx:U33>0.4186</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3245">
         <PDBx:U11>0.2888</PDBx:U11>
         <PDBx:U12>-0.0653</PDBx:U12>
         <PDBx:U13>-0.1002</PDBx:U13>
         <PDBx:U22>0.5696</PDBx:U22>
         <PDBx:U23>0.0240</PDBx:U23>
         <PDBx:U33>0.3743</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3246">
         <PDBx:U11>0.2291</PDBx:U11>
         <PDBx:U12>-0.0894</PDBx:U12>
         <PDBx:U13>-0.1107</PDBx:U13>
         <PDBx:U22>0.5818</PDBx:U22>
         <PDBx:U23>0.0182</PDBx:U23>
         <PDBx:U33>0.3521</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3247">
         <PDBx:U11>0.3036</PDBx:U11>
         <PDBx:U12>-0.0889</PDBx:U12>
         <PDBx:U13>-0.0963</PDBx:U13>
         <PDBx:U22>0.5510</PDBx:U22>
         <PDBx:U23>0.0181</PDBx:U23>
         <PDBx:U33>0.3678</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>487</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>187</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3248">
         <PDBx:U11>0.2596</PDBx:U11>
         <PDBx:U12>-0.0778</PDBx:U12>
         <PDBx:U13>-0.0757</PDBx:U13>
         <PDBx:U22>0.6488</PDBx:U22>
         <PDBx:U23>0.0250</PDBx:U23>
         <PDBx:U33>0.4310</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3249">
         <PDBx:U11>0.3333</PDBx:U11>
         <PDBx:U12>-0.0878</PDBx:U12>
         <PDBx:U13>-0.0719</PDBx:U13>
         <PDBx:U22>0.7675</PDBx:U22>
         <PDBx:U23>0.0234</PDBx:U23>
         <PDBx:U33>0.5322</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3250">
         <PDBx:U11>0.3241</PDBx:U11>
         <PDBx:U12>-0.1108</PDBx:U12>
         <PDBx:U13>-0.0584</PDBx:U13>
         <PDBx:U22>0.7408</PDBx:U22>
         <PDBx:U23>0.0236</PDBx:U23>
         <PDBx:U33>0.5154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3251">
         <PDBx:U11>0.2238</PDBx:U11>
         <PDBx:U12>-0.1337</PDBx:U12>
         <PDBx:U13>-0.0585</PDBx:U13>
         <PDBx:U22>0.6608</PDBx:U22>
         <PDBx:U23>0.0209</PDBx:U23>
         <PDBx:U33>0.4251</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3252">
         <PDBx:U11>0.3764</PDBx:U11>
         <PDBx:U12>-0.0634</PDBx:U12>
         <PDBx:U13>-0.0665</PDBx:U13>
         <PDBx:U22>0.8418</PDBx:U22>
         <PDBx:U23>0.0253</PDBx:U23>
         <PDBx:U33>0.5988</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3253">
         <PDBx:U11>0.4090</PDBx:U11>
         <PDBx:U12>-0.0725</PDBx:U12>
         <PDBx:U13>-0.0601</PDBx:U13>
         <PDBx:U22>0.9235</PDBx:U22>
         <PDBx:U23>0.0231</PDBx:U23>
         <PDBx:U33>0.6613</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3254">
         <PDBx:U11>0.4493</PDBx:U11>
         <PDBx:U12>-0.0785</PDBx:U12>
         <PDBx:U13>-0.0710</PDBx:U13>
         <PDBx:U22>1.0150</PDBx:U22>
         <PDBx:U23>0.0204</PDBx:U23>
         <PDBx:U33>0.7283</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3255">
         <PDBx:U11>0.4247</PDBx:U11>
         <PDBx:U12>-0.0776</PDBx:U12>
         <PDBx:U13>-0.0439</PDBx:U13>
         <PDBx:U22>0.9473</PDBx:U22>
         <PDBx:U23>0.0231</PDBx:U23>
         <PDBx:U33>0.6842</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3256">
         <PDBx:U11>0.4756</PDBx:U11>
         <PDBx:U12>-0.0872</PDBx:U12>
         <PDBx:U13>-0.0606</PDBx:U13>
         <PDBx:U22>1.0801</PDBx:U22>
         <PDBx:U23>0.0184</PDBx:U23>
         <PDBx:U33>0.7792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3257">
         <PDBx:U11>0.4760</PDBx:U11>
         <PDBx:U12>-0.0869</PDBx:U12>
         <PDBx:U13>-0.0438</PDBx:U13>
         <PDBx:U22>1.0538</PDBx:U22>
         <PDBx:U23>0.0201</PDBx:U23>
         <PDBx:U33>0.7669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>488</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>188</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3258">
         <PDBx:U11>0.2029</PDBx:U11>
         <PDBx:U12>-0.1049</PDBx:U12>
         <PDBx:U13>-0.0476</PDBx:U13>
         <PDBx:U22>0.5820</PDBx:U22>
         <PDBx:U23>0.0273</PDBx:U23>
         <PDBx:U33>0.3759</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3259">
         <PDBx:U11>0.2561</PDBx:U11>
         <PDBx:U12>-0.1228</PDBx:U12>
         <PDBx:U13>-0.0362</PDBx:U13>
         <PDBx:U22>0.6142</PDBx:U22>
         <PDBx:U23>0.0302</PDBx:U23>
         <PDBx:U33>0.4185</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3260">
         <PDBx:U11>0.2651</PDBx:U11>
         <PDBx:U12>-0.1468</PDBx:U12>
         <PDBx:U13>-0.0401</PDBx:U13>
         <PDBx:U22>0.5950</PDBx:U22>
         <PDBx:U23>0.0285</PDBx:U23>
         <PDBx:U33>0.4122</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3261">
         <PDBx:U11>0.2922</PDBx:U11>
         <PDBx:U12>-0.1688</PDBx:U12>
         <PDBx:U13>-0.0344</PDBx:U13>
         <PDBx:U22>0.6224</PDBx:U22>
         <PDBx:U23>0.0292</PDBx:U23>
         <PDBx:U33>0.4411</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3262">
         <PDBx:U11>0.2779</PDBx:U11>
         <PDBx:U12>-0.1093</PDBx:U12>
         <PDBx:U13>-0.0273</PDBx:U13>
         <PDBx:U22>0.6018</PDBx:U22>
         <PDBx:U23>0.0348</PDBx:U23>
         <PDBx:U33>0.4220</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3263">
         <PDBx:U11>0.2808</PDBx:U11>
         <PDBx:U12>-0.0880</PDBx:U12>
         <PDBx:U13>-0.0207</PDBx:U13>
         <PDBx:U22>0.6246</PDBx:U22>
         <PDBx:U23>0.0346</PDBx:U23>
         <PDBx:U33>0.4353</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3264">
         <PDBx:U11>0.2727</PDBx:U11>
         <PDBx:U12>-0.0760</PDBx:U12>
         <PDBx:U13>-0.0154</PDBx:U13>
         <PDBx:U22>0.5802</PDBx:U22>
         <PDBx:U23>0.0369</PDBx:U23>
         <PDBx:U33>0.4060</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3265">
         <PDBx:U11>0.3343</PDBx:U11>
         <PDBx:U12>-0.0960</PDBx:U12>
         <PDBx:U13>-0.0107</PDBx:U13>
         <PDBx:U22>0.7113</PDBx:U22>
         <PDBx:U23>0.0348</PDBx:U23>
         <PDBx:U33>0.5050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>489</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>189</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3266">
         <PDBx:U11>0.2689</PDBx:U11>
         <PDBx:U12>-0.1433</PDBx:U12>
         <PDBx:U13>-0.0487</PDBx:U13>
         <PDBx:U22>0.5722</PDBx:U22>
         <PDBx:U23>0.0258</PDBx:U23>
         <PDBx:U33>0.3999</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3267">
         <PDBx:U11>0.2489</PDBx:U11>
         <PDBx:U12>-0.1644</PDBx:U12>
         <PDBx:U13>-0.0515</PDBx:U13>
         <PDBx:U22>0.5196</PDBx:U22>
         <PDBx:U23>0.0218</PDBx:U23>
         <PDBx:U33>0.3625</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3268">
         <PDBx:U11>0.3289</PDBx:U11>
         <PDBx:U12>-0.1861</PDBx:U12>
         <PDBx:U13>-0.0589</PDBx:U13>
         <PDBx:U22>0.6297</PDBx:U22>
         <PDBx:U23>0.0148</PDBx:U23>
         <PDBx:U33>0.4548</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3269">
         <PDBx:U11>0.3152</PDBx:U11>
         <PDBx:U12>-0.2107</PDBx:U12>
         <PDBx:U13>-0.0557</PDBx:U13>
         <PDBx:U22>0.5963</PDBx:U22>
         <PDBx:U23>0.0114</PDBx:U23>
         <PDBx:U33>0.4333</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3270">
         <PDBx:U11>0.2788</PDBx:U11>
         <PDBx:U12>-0.1545</PDBx:U12>
         <PDBx:U13>-0.0579</PDBx:U13>
         <PDBx:U22>0.5169</PDBx:U22>
         <PDBx:U23>0.0191</PDBx:U23>
         <PDBx:U33>0.3714</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3271">
         <PDBx:U11>0.2905</PDBx:U11>
         <PDBx:U12>-0.1361</PDBx:U12>
         <PDBx:U13>-0.0507</PDBx:U13>
         <PDBx:U22>0.5002</PDBx:U22>
         <PDBx:U23>0.0250</PDBx:U23>
         <PDBx:U33>0.3719</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3272">
         <PDBx:U11>0.3363</PDBx:U11>
         <PDBx:U12>-0.1249</PDBx:U12>
         <PDBx:U13>-0.0572</PDBx:U13>
         <PDBx:U22>0.5150</PDBx:U22>
         <PDBx:U23>0.0216</PDBx:U23>
         <PDBx:U33>0.3957</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3273">
         <PDBx:U11>0.3579</PDBx:U11>
         <PDBx:U12>-0.1075</PDBx:U12>
         <PDBx:U13>-0.0467</PDBx:U13>
         <PDBx:U22>0.5141</PDBx:U22>
         <PDBx:U23>0.0286</PDBx:U23>
         <PDBx:U33>0.4118</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>490</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>190</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3274">
         <PDBx:U11>0.2608</PDBx:U11>
         <PDBx:U12>-0.1766</PDBx:U12>
         <PDBx:U13>-0.0689</PDBx:U13>
         <PDBx:U22>0.6089</PDBx:U22>
         <PDBx:U23>0.0125</PDBx:U23>
         <PDBx:U33>0.4065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3275">
         <PDBx:U11>0.3599</PDBx:U11>
         <PDBx:U12>-0.1961</PDBx:U12>
         <PDBx:U13>-0.0775</PDBx:U13>
         <PDBx:U22>0.7481</PDBx:U22>
         <PDBx:U23>0.0058</PDBx:U23>
         <PDBx:U33>0.5220</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3276">
         <PDBx:U11>0.4093</PDBx:U11>
         <PDBx:U12>-0.2153</PDBx:U12>
         <PDBx:U13>-0.0664</PDBx:U13>
         <PDBx:U22>0.8191</PDBx:U22>
         <PDBx:U23>0.0070</PDBx:U23>
         <PDBx:U33>0.5888</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3277">
         <PDBx:U11>0.4110</PDBx:U11>
         <PDBx:U12>-0.2439</PDBx:U12>
         <PDBx:U13>-0.0669</PDBx:U13>
         <PDBx:U22>0.8259</PDBx:U22>
         <PDBx:U23>0.0012</PDBx:U23>
         <PDBx:U33>0.5920</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3278">
         <PDBx:U11>0.3208</PDBx:U11>
         <PDBx:U12>-0.1768</PDBx:U12>
         <PDBx:U13>-0.0912</PDBx:U13>
         <PDBx:U22>0.7591</PDBx:U22>
         <PDBx:U23>0.0054</PDBx:U23>
         <PDBx:U33>0.5040</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>491</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>191</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3279">
         <PDBx:U11>0.4368</PDBx:U11>
         <PDBx:U12>-0.2009</PDBx:U12>
         <PDBx:U13>-0.0555</PDBx:U13>
         <PDBx:U22>0.8578</PDBx:U22>
         <PDBx:U23>0.0138</PDBx:U23>
         <PDBx:U33>0.6275</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3280">
         <PDBx:U11>0.4624</PDBx:U11>
         <PDBx:U12>-0.2178</PDBx:U12>
         <PDBx:U13>-0.0430</PDBx:U13>
         <PDBx:U22>0.9029</PDBx:U22>
         <PDBx:U23>0.0161</PDBx:U23>
         <PDBx:U33>0.6668</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3281">
         <PDBx:U11>0.4440</PDBx:U11>
         <PDBx:U12>-0.2411</PDBx:U12>
         <PDBx:U13>-0.0335</PDBx:U13>
         <PDBx:U22>0.8329</PDBx:U22>
         <PDBx:U23>0.0189</PDBx:U23>
         <PDBx:U33>0.6248</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3282">
         <PDBx:U11>0.4931</PDBx:U11>
         <PDBx:U12>-0.2670</PDBx:U12>
         <PDBx:U13>-0.0263</PDBx:U13>
         <PDBx:U22>0.8908</PDBx:U22>
         <PDBx:U23>0.0185</PDBx:U23>
         <PDBx:U33>0.6804</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3283">
         <PDBx:U11>0.4806</PDBx:U11>
         <PDBx:U12>-0.1959</PDBx:U12>
         <PDBx:U13>-0.0327</PDBx:U13>
         <PDBx:U22>0.9383</PDBx:U22>
         <PDBx:U23>0.0220</PDBx:U23>
         <PDBx:U33>0.6960</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3284">
         <PDBx:U11>0.5717</PDBx:U11>
         <PDBx:U12>-0.2133</PDBx:U12>
         <PDBx:U13>-0.0180</PDBx:U13>
         <PDBx:U22>1.0466</PDBx:U22>
         <PDBx:U23>0.0251</PDBx:U23>
         <PDBx:U33>0.7968</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3285">
         <PDBx:U11>0.5877</PDBx:U11>
         <PDBx:U12>-0.1920</PDBx:U12>
         <PDBx:U13>-0.0071</PDBx:U13>
         <PDBx:U22>1.0759</PDBx:U22>
         <PDBx:U23>0.0292</PDBx:U23>
         <PDBx:U33>0.8188</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3286">
         <PDBx:U11>0.5765</PDBx:U11>
         <PDBx:U12>-0.1711</PDBx:U12>
         <PDBx:U13>-0.0114</PDBx:U13>
         <PDBx:U22>1.1202</PDBx:U22>
         <PDBx:U23>0.0242</PDBx:U23>
         <PDBx:U33>0.8393</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3287">
         <PDBx:U11>0.5420</PDBx:U11>
         <PDBx:U12>-0.1556</PDBx:U12>
         <PDBx:U13>0.0023</PDBx:U13>
         <PDBx:U22>1.1025</PDBx:U22>
         <PDBx:U23>0.0256</PDBx:U23>
         <PDBx:U33>0.8130</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>492</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>192</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3288">
         <PDBx:U11>0.4009</PDBx:U11>
         <PDBx:U12>-0.2315</PDBx:U12>
         <PDBx:U13>-0.0330</PDBx:U13>
         <PDBx:U22>0.7356</PDBx:U22>
         <PDBx:U23>0.0219</PDBx:U23>
         <PDBx:U33>0.5553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3289">
         <PDBx:U11>0.4370</PDBx:U11>
         <PDBx:U12>-0.2478</PDBx:U12>
         <PDBx:U13>-0.0242</PDBx:U13>
         <PDBx:U22>0.7173</PDBx:U22>
         <PDBx:U23>0.0258</PDBx:U23>
         <PDBx:U33>0.5695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3290">
         <PDBx:U11>0.4552</PDBx:U11>
         <PDBx:U12>-0.2750</PDBx:U12>
         <PDBx:U13>-0.0285</PDBx:U13>
         <PDBx:U22>0.7148</PDBx:U22>
         <PDBx:U23>0.0169</PDBx:U23>
         <PDBx:U33>0.5790</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3291">
         <PDBx:U11>0.4866</PDBx:U11>
         <PDBx:U12>-0.2919</PDBx:U12>
         <PDBx:U13>-0.0202</PDBx:U13>
         <PDBx:U22>0.7001</PDBx:U22>
         <PDBx:U23>0.0191</PDBx:U23>
         <PDBx:U33>0.5948</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3292">
         <PDBx:U11>0.4491</PDBx:U11>
         <PDBx:U12>-0.2270</PDBx:U12>
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         <PDBx:U23>0.0312</PDBx:U23>
         <PDBx:U33>0.5602</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>493</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>193</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3293">
         <PDBx:U11>0.4046</PDBx:U11>
         <PDBx:U12>-0.2785</PDBx:U12>
         <PDBx:U13>-0.0414</PDBx:U13>
         <PDBx:U22>0.6966</PDBx:U22>
         <PDBx:U23>0.0069</PDBx:U23>
         <PDBx:U33>0.5374</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3294">
         <PDBx:U11>0.4464</PDBx:U11>
         <PDBx:U12>-0.3065</PDBx:U12>
         <PDBx:U13>-0.0464</PDBx:U13>
         <PDBx:U22>0.7267</PDBx:U22>
         <PDBx:U23>-0.0042</PDBx:U23>
         <PDBx:U33>0.5710</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.4793</PDBx:U11>
         <PDBx:U12>-0.3021</PDBx:U12>
         <PDBx:U13>-0.0533</PDBx:U13>
         <PDBx:U22>0.7154</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.5775</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3296">
         <PDBx:U11>0.4771</PDBx:U11>
         <PDBx:U12>-0.3252</PDBx:U12>
         <PDBx:U13>-0.0560</PDBx:U13>
         <PDBx:U22>0.6934</PDBx:U22>
         <PDBx:U23>-0.0225</PDBx:U23>
         <PDBx:U33>0.5624</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>494</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>194</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3297">
         <PDBx:U11>0.3940</PDBx:U11>
         <PDBx:U12>-0.2738</PDBx:U12>
         <PDBx:U13>-0.0551</PDBx:U13>
         <PDBx:U22>0.6143</PDBx:U22>
         <PDBx:U23>-0.0066</PDBx:U23>
         <PDBx:U33>0.4832</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3298">
         <PDBx:U11>0.4484</PDBx:U11>
         <PDBx:U12>-0.2679</PDBx:U12>
         <PDBx:U13>-0.0605</PDBx:U13>
         <PDBx:U22>0.6302</PDBx:U22>
         <PDBx:U23>-0.0137</PDBx:U23>
         <PDBx:U33>0.5128</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.4761</PDBx:U11>
         <PDBx:U12>-0.2727</PDBx:U12>
         <PDBx:U13>-0.0762</PDBx:U13>
         <PDBx:U22>0.6919</PDBx:U22>
         <PDBx:U23>-0.0240</PDBx:U23>
         <PDBx:U33>0.5410</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3300">
         <PDBx:U11>0.3960</PDBx:U11>
         <PDBx:U12>-0.2654</PDBx:U12>
         <PDBx:U13>-0.0852</PDBx:U13>
         <PDBx:U22>0.6685</PDBx:U22>
         <PDBx:U23>-0.0218</PDBx:U23>
         <PDBx:U33>0.4837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3301">
         <PDBx:U11>0.3527</PDBx:U11>
         <PDBx:U12>-0.2377</PDBx:U12>
         <PDBx:U13>-0.0585</PDBx:U13>
         <PDBx:U22>0.5172</PDBx:U22>
         <PDBx:U23>-0.0057</PDBx:U23>
         <PDBx:U33>0.4099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3302">
         <PDBx:U11>0.3645</PDBx:U11>
         <PDBx:U12>-0.2313</PDBx:U12>
         <PDBx:U13>-0.0456</PDBx:U13>
         <PDBx:U22>0.4788</PDBx:U22>
         <PDBx:U23>0.0017</PDBx:U23>
         <PDBx:U33>0.4101</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3303">
         <PDBx:U11>0.3739</PDBx:U11>
         <PDBx:U12>-0.2408</PDBx:U12>
         <PDBx:U13>-0.0352</PDBx:U13>
         <PDBx:U22>0.4937</PDBx:U22>
         <PDBx:U23>0.0109</PDBx:U23>
         <PDBx:U33>0.4320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3304">
         <PDBx:U11>0.3230</PDBx:U11>
         <PDBx:U12>-0.2030</PDBx:U12>
         <PDBx:U13>-0.0456</PDBx:U13>
         <PDBx:U22>0.4329</PDBx:U22>
         <PDBx:U23>0.0081</PDBx:U23>
         <PDBx:U33>0.3649</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>495</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>195</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.4415</PDBx:U11>
         <PDBx:U12>-0.2837</PDBx:U12>
         <PDBx:U13>-0.0795</PDBx:U13>
         <PDBx:U22>0.6226</PDBx:U22>
         <PDBx:U23>-0.0353</PDBx:U23>
         <PDBx:U33>0.4810</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.5219</PDBx:U11>
         <PDBx:U12>-0.2879</PDBx:U12>
         <PDBx:U13>-0.0954</PDBx:U13>
         <PDBx:U22>0.7313</PDBx:U22>
         <PDBx:U23>-0.0450</PDBx:U23>
         <PDBx:U33>0.5557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.4558</PDBx:U11>
         <PDBx:U12>-0.2577</PDBx:U12>
         <PDBx:U13>-0.1034</PDBx:U13>
         <PDBx:U22>0.6741</PDBx:U22>
         <PDBx:U23>-0.0389</PDBx:U23>
         <PDBx:U33>0.4848</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.3954</PDBx:U11>
         <PDBx:U12>-0.2372</PDBx:U12>
         <PDBx:U13>-0.0952</PDBx:U13>
         <PDBx:U22>0.5910</PDBx:U22>
         <PDBx:U23>-0.0300</PDBx:U23>
         <PDBx:U33>0.4222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3309">
         <PDBx:U11>0.6151</PDBx:U11>
         <PDBx:U12>-0.3102</PDBx:U12>
         <PDBx:U13>-0.0949</PDBx:U13>
         <PDBx:U22>0.7816</PDBx:U22>
         <PDBx:U23>-0.0608</PDBx:U23>
         <PDBx:U33>0.6185</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3310">
         <PDBx:U11>0.5033</PDBx:U11>
         <PDBx:U12>-0.2963</PDBx:U12>
         <PDBx:U13>-0.0859</PDBx:U13>
         <PDBx:U22>0.6114</PDBx:U22>
         <PDBx:U23>-0.0612</PDBx:U23>
         <PDBx:U33>0.4816</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3311">
         <PDBx:U11>0.5575</PDBx:U11>
         <PDBx:U12>-0.3414</PDBx:U12>
         <PDBx:U13>-0.0857</PDBx:U13>
         <PDBx:U22>0.7069</PDBx:U22>
         <PDBx:U23>-0.0671</PDBx:U23>
         <PDBx:U33>0.5631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>THR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>496</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>THR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>196</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3312">
         <PDBx:U11>0.4789</PDBx:U11>
         <PDBx:U12>-0.2555</PDBx:U12>
         <PDBx:U13>-0.1197</PDBx:U13>
         <PDBx:U22>0.7300</PDBx:U22>
         <PDBx:U23>-0.0434</PDBx:U23>
         <PDBx:U33>0.5054</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3313">
         <PDBx:U11>0.5245</PDBx:U11>
         <PDBx:U12>-0.2274</PDBx:U12>
         <PDBx:U13>-0.1284</PDBx:U13>
         <PDBx:U22>0.7828</PDBx:U22>
         <PDBx:U23>-0.0367</PDBx:U23>
         <PDBx:U33>0.5444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3314">
         <PDBx:U11>0.4846</PDBx:U11>
         <PDBx:U12>-0.2192</PDBx:U12>
         <PDBx:U13>-0.1190</PDBx:U13>
         <PDBx:U22>0.6838</PDBx:U22>
         <PDBx:U23>-0.0381</PDBx:U23>
         <PDBx:U33>0.4733</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3315">
         <PDBx:U11>0.4044</PDBx:U11>
         <PDBx:U12>-0.1958</PDBx:U12>
         <PDBx:U13>-0.1151</PDBx:U13>
         <PDBx:U22>0.5939</PDBx:U22>
         <PDBx:U23>-0.0288</PDBx:U23>
         <PDBx:U33>0.3931</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3316">
         <PDBx:U11>0.6165</PDBx:U11>
         <PDBx:U12>-0.2292</PDBx:U12>
         <PDBx:U13>-0.1488</PDBx:U13>
         <PDBx:U22>0.9118</PDBx:U22>
         <PDBx:U23>-0.0419</PDBx:U23>
         <PDBx:U33>0.6314</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3317">
         <PDBx:U11>0.6591</PDBx:U11>
         <PDBx:U12>-0.1976</PDBx:U12>
         <PDBx:U13>-0.1616</PDBx:U13>
         <PDBx:U22>0.9835</PDBx:U22>
         <PDBx:U23>-0.0307</PDBx:U23>
         <PDBx:U33>0.6813</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3318">
         <PDBx:U11>0.6350</PDBx:U11>
         <PDBx:U12>-0.1815</PDBx:U12>
         <PDBx:U13>-0.1589</PDBx:U13>
         <PDBx:U22>0.9988</PDBx:U22>
         <PDBx:U23>-0.0199</PDBx:U23>
         <PDBx:U33>0.6967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3319">
         <PDBx:U11>0.7399</PDBx:U11>
         <PDBx:U12>-0.2000</PDBx:U12>
         <PDBx:U13>-0.1837</PDBx:U13>
         <PDBx:U22>1.0982</PDBx:U22>
         <PDBx:U23>-0.0349</PDBx:U23>
         <PDBx:U33>0.7532</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>497</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>197</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3320">
         <PDBx:U11>0.4375</PDBx:U11>
         <PDBx:U12>-0.2388</PDBx:U12>
         <PDBx:U13>-0.1143</PDBx:U13>
         <PDBx:U22>0.5973</PDBx:U22>
         <PDBx:U23>-0.0510</PDBx:U23>
         <PDBx:U33>0.4002</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3321">
         <PDBx:U11>0.5183</PDBx:U11>
         <PDBx:U12>-0.2321</PDBx:U12>
         <PDBx:U13>-0.1034</PDBx:U13>
         <PDBx:U22>0.6218</PDBx:U22>
         <PDBx:U23>-0.0547</PDBx:U23>
         <PDBx:U33>0.4526</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3322">
         <PDBx:U11>0.4548</PDBx:U11>
         <PDBx:U12>-0.2205</PDBx:U12>
         <PDBx:U13>-0.0882</PDBx:U13>
         <PDBx:U22>0.5310</PDBx:U22>
         <PDBx:U23>-0.0456</PDBx:U23>
         <PDBx:U33>0.3999</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3323">
         <PDBx:U11>0.4740</PDBx:U11>
         <PDBx:U12>-0.2028</PDBx:U12>
         <PDBx:U13>-0.0823</PDBx:U13>
         <PDBx:U22>0.5261</PDBx:U22>
         <PDBx:U23>-0.0415</PDBx:U23>
         <PDBx:U33>0.4089</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3324">
         <PDBx:U11>0.5695</PDBx:U11>
         <PDBx:U12>-0.2555</PDBx:U12>
         <PDBx:U13>-0.0986</PDBx:U13>
         <PDBx:U22>0.6349</PDBx:U22>
         <PDBx:U23>-0.0720</PDBx:U23>
         <PDBx:U33>0.4774</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3325">
         <PDBx:U11>0.6420</PDBx:U11>
         <PDBx:U12>-0.2472</PDBx:U12>
         <PDBx:U13>-0.0860</PDBx:U13>
         <PDBx:U22>0.6512</PDBx:U22>
         <PDBx:U23>-0.0784</PDBx:U23>
         <PDBx:U33>0.5212</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3326">
         <PDBx:U11>0.7329</PDBx:U11>
         <PDBx:U12>-0.2684</PDBx:U12>
         <PDBx:U13>-0.0808</PDBx:U13>
         <PDBx:U22>0.7062</PDBx:U22>
         <PDBx:U23>-0.0975</PDBx:U23>
         <PDBx:U33>0.5853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3327">
         <PDBx:U11>0.8366</PDBx:U11>
         <PDBx:U12>-0.2918</PDBx:U12>
         <PDBx:U13>-0.0878</PDBx:U13>
         <PDBx:U22>0.8265</PDBx:U22>
         <PDBx:U23>-0.1064</PDBx:U23>
         <PDBx:U33>0.6892</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3328">
         <PDBx:U11>0.7005</PDBx:U11>
         <PDBx:U12>-0.2603</PDBx:U12>
         <PDBx:U13>-0.0677</PDBx:U13>
         <PDBx:U22>0.6256</PDBx:U22>
         <PDBx:U23>-0.1048</PDBx:U23>
         <PDBx:U33>0.5304</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>498</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>198</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3329">
         <PDBx:U11>0.4055</PDBx:U11>
         <PDBx:U12>-0.2313</PDBx:U12>
         <PDBx:U13>-0.0822</PDBx:U13>
         <PDBx:U22>0.4872</PDBx:U22>
         <PDBx:U23>-0.0422</PDBx:U23>
         <PDBx:U33>0.3705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3330">
         <PDBx:U11>0.3809</PDBx:U11>
         <PDBx:U12>-0.2217</PDBx:U12>
         <PDBx:U13>-0.0690</PDBx:U13>
         <PDBx:U22>0.4387</PDBx:U22>
         <PDBx:U23>-0.0326</PDBx:U23>
         <PDBx:U33>0.3553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3331">
         <PDBx:U11>0.3681</PDBx:U11>
         <PDBx:U12>-0.1981</PDBx:U12>
         <PDBx:U13>-0.0706</PDBx:U13>
         <PDBx:U22>0.4561</PDBx:U22>
         <PDBx:U23>-0.0190</PDBx:U23>
         <PDBx:U33>0.3601</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3332">
         <PDBx:U11>0.3412</PDBx:U11>
         <PDBx:U12>-0.1836</PDBx:U12>
         <PDBx:U13>-0.0622</PDBx:U13>
         <PDBx:U22>0.4066</PDBx:U22>
         <PDBx:U23>-0.0123</PDBx:U23>
         <PDBx:U33>0.3318</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3333">
         <PDBx:U11>0.4044</PDBx:U11>
         <PDBx:U12>-0.2411</PDBx:U12>
         <PDBx:U13>-0.0623</PDBx:U13>
         <PDBx:U22>0.4599</PDBx:U22>
         <PDBx:U23>-0.0315</PDBx:U23>
         <PDBx:U33>0.3921</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3334">
         <PDBx:U11>0.5015</PDBx:U11>
         <PDBx:U12>-0.2635</PDBx:U12>
         <PDBx:U13>-0.0567</PDBx:U13>
         <PDBx:U22>0.5131</PDBx:U22>
         <PDBx:U23>-0.0446</PDBx:U23>
         <PDBx:U33>0.4705</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3335">
         <PDBx:U11>0.5748</PDBx:U11>
         <PDBx:U12>-0.2857</PDBx:U12>
         <PDBx:U13>-0.0505</PDBx:U13>
         <PDBx:U22>0.5850</PDBx:U22>
         <PDBx:U23>-0.0429</PDBx:U23>
         <PDBx:U33>0.5561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3336">
         <PDBx:U11>0.5295</PDBx:U11>
         <PDBx:U12>-0.2911</PDBx:U12>
         <PDBx:U13>-0.0541</PDBx:U13>
         <PDBx:U22>0.5868</PDBx:U22>
         <PDBx:U23>-0.0365</PDBx:U23>
         <PDBx:U33>0.5333</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3337">
         <PDBx:U11>0.6136</PDBx:U11>
         <PDBx:U12>-0.2983</PDBx:U12>
         <PDBx:U13>-0.0399</PDBx:U13>
         <PDBx:U22>0.5684</PDBx:U22>
         <PDBx:U23>-0.0487</PDBx:U23>
         <PDBx:U33>0.5803</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>499</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>199</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3338">
         <PDBx:U11>0.3638</PDBx:U11>
         <PDBx:U12>-0.1936</PDBx:U12>
         <PDBx:U13>-0.0812</PDBx:U13>
         <PDBx:U22>0.5033</PDBx:U22>
         <PDBx:U23>-0.0156</PDBx:U23>
         <PDBx:U33>0.3735</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3339">
         <PDBx:U11>0.2872</PDBx:U11>
         <PDBx:U12>-0.1698</PDBx:U12>
         <PDBx:U13>-0.0821</PDBx:U13>
         <PDBx:U22>0.4543</PDBx:U22>
         <PDBx:U23>-0.0046</PDBx:U23>
         <PDBx:U33>0.3136</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3340">
         <PDBx:U11>0.3126</PDBx:U11>
         <PDBx:U12>-0.1514</PDBx:U12>
         <PDBx:U13>-0.0834</PDBx:U13>
         <PDBx:U22>0.4578</PDBx:U22>
         <PDBx:U23>-0.0032</PDBx:U23>
         <PDBx:U33>0.3205</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3341">
         <PDBx:U11>0.2886</PDBx:U11>
         <PDBx:U12>-0.1365</PDBx:U12>
         <PDBx:U13>-0.0758</PDBx:U13>
         <PDBx:U22>0.4216</PDBx:U22>
         <PDBx:U23>0.0037</PDBx:U23>
         <PDBx:U33>0.2984</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3342">
         <PDBx:U11>0.3270</PDBx:U11>
         <PDBx:U12>-0.1659</PDBx:U12>
         <PDBx:U13>-0.0938</PDBx:U13>
         <PDBx:U22>0.5508</PDBx:U22>
         <PDBx:U23>-0.0031</PDBx:U23>
         <PDBx:U33>0.3761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3343">
         <PDBx:U11>0.3137</PDBx:U11>
         <PDBx:U12>-0.1852</PDBx:U12>
         <PDBx:U13>-0.0920</PDBx:U13>
         <PDBx:U22>0.5667</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.3841</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3344">
         <PDBx:U11>0.3546</PDBx:U11>
         <PDBx:U12>-0.1825</PDBx:U12>
         <PDBx:U13>-0.1053</PDBx:U13>
         <PDBx:U22>0.6668</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.4483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3345">
         <PDBx:U11>0.3495</PDBx:U11>
         <PDBx:U12>-0.1584</PDBx:U12>
         <PDBx:U13>-0.1129</PDBx:U13>
         <PDBx:U22>0.6839</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.4514</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3346">
         <PDBx:U11>0.3355</PDBx:U11>
         <PDBx:U12>-0.2069</PDBx:U12>
         <PDBx:U13>-0.1084</PDBx:U13>
         <PDBx:U22>0.6728</PDBx:U22>
         <PDBx:U23>-0.0120</PDBx:U23>
         <PDBx:U33>0.4405</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>500</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>200</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3347">
         <PDBx:U11>0.3323</PDBx:U11>
         <PDBx:U12>-0.1540</PDBx:U12>
         <PDBx:U13>-0.0930</PDBx:U13>
         <PDBx:U22>0.4730</PDBx:U22>
         <PDBx:U23>-0.0101</PDBx:U23>
         <PDBx:U33>0.3203</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3348">
         <PDBx:U11>0.3857</PDBx:U11>
         <PDBx:U12>-0.1394</PDBx:U12>
         <PDBx:U13>-0.0939</PDBx:U13>
         <PDBx:U22>0.5043</PDBx:U22>
         <PDBx:U23>-0.0093</PDBx:U23>
         <PDBx:U33>0.3513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3349">
         <PDBx:U11>0.3904</PDBx:U11>
         <PDBx:U12>-0.1403</PDBx:U12>
         <PDBx:U13>-0.0797</PDBx:U13>
         <PDBx:U22>0.4604</PDBx:U22>
         <PDBx:U23>-0.0120</PDBx:U23>
         <PDBx:U33>0.3402</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3350">
         <PDBx:U11>0.3456</PDBx:U11>
         <PDBx:U12>-0.1254</PDBx:U12>
         <PDBx:U13>-0.0751</PDBx:U13>
         <PDBx:U22>0.4023</PDBx:U22>
         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.2897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3351">
         <PDBx:U11>0.4548</PDBx:U11>
         <PDBx:U12>-0.1454</PDBx:U12>
         <PDBx:U13>-0.1057</PDBx:U13>
         <PDBx:U22>0.5744</PDBx:U22>
         <PDBx:U23>-0.0170</PDBx:U23>
         <PDBx:U33>0.3965</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3352">
         <PDBx:U11>0.4959</PDBx:U11>
         <PDBx:U12>-0.1402</PDBx:U12>
         <PDBx:U13>-0.1225</PDBx:U13>
         <PDBx:U22>0.6648</PDBx:U22>
         <PDBx:U23>-0.0135</PDBx:U23>
         <PDBx:U33>0.4523</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3353">
         <PDBx:U11>0.4905</PDBx:U11>
         <PDBx:U12>-0.1208</PDBx:U12>
         <PDBx:U13>-0.1263</PDBx:U13>
         <PDBx:U22>0.6935</PDBx:U22>
         <PDBx:U23>-0.0028</PDBx:U23>
         <PDBx:U33>0.4740</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3354">
         <PDBx:U11>0.4970</PDBx:U11>
         <PDBx:U12>-0.1508</PDBx:U12>
         <PDBx:U13>-0.1369</PDBx:U13>
         <PDBx:U22>0.6874</PDBx:U22>
         <PDBx:U23>-0.0199</PDBx:U23>
         <PDBx:U33>0.4452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3355">
         <PDBx:U11>0.3993</PDBx:U11>
         <PDBx:U12>-0.1179</PDBx:U12>
         <PDBx:U13>-0.1425</PDBx:U13>
         <PDBx:U22>0.6425</PDBx:U22>
         <PDBx:U23>-0.0020</PDBx:U23>
         <PDBx:U33>0.3926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3356">
         <PDBx:U11>0.4788</PDBx:U11>
         <PDBx:U12>-0.1365</PDBx:U12>
         <PDBx:U13>-0.1502</PDBx:U13>
         <PDBx:U22>0.7173</PDBx:U22>
         <PDBx:U23>-0.0119</PDBx:U23>
         <PDBx:U33>0.4511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>501</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>201</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3357">
         <PDBx:U11>0.3582</PDBx:U11>
         <PDBx:U12>-0.1568</PDBx:U12>
         <PDBx:U13>-0.0725</PDBx:U13>
         <PDBx:U22>0.4010</PDBx:U22>
         <PDBx:U23>-0.0202</PDBx:U23>
         <PDBx:U33>0.3018</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3358">
         <PDBx:U11>0.3834</PDBx:U11>
         <PDBx:U12>-0.1541</PDBx:U12>
         <PDBx:U13>-0.0587</PDBx:U13>
         <PDBx:U22>0.3799</PDBx:U22>
         <PDBx:U23>-0.0235</PDBx:U23>
         <PDBx:U33>0.3159</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3359">
         <PDBx:U11>0.3225</PDBx:U11>
         <PDBx:U12>-0.1419</PDBx:U12>
         <PDBx:U13>-0.0515</PDBx:U13>
         <PDBx:U22>0.3205</PDBx:U22>
         <PDBx:U23>-0.0121</PDBx:U23>
         <PDBx:U33>0.2745</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3360">
         <PDBx:U11>0.3539</PDBx:U11>
         <PDBx:U12>-0.1295</PDBx:U12>
         <PDBx:U13>-0.0445</PDBx:U13>
         <PDBx:U22>0.3317</PDBx:U22>
         <PDBx:U23>-0.0108</PDBx:U23>
         <PDBx:U33>0.3006</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3361">
         <PDBx:U11>0.3946</PDBx:U11>
         <PDBx:U12>-0.1712</PDBx:U12>
         <PDBx:U13>-0.0523</PDBx:U13>
         <PDBx:U22>0.3596</PDBx:U22>
         <PDBx:U23>-0.0344</PDBx:U23>
         <PDBx:U33>0.3187</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3362">
         <PDBx:U11>0.4859</PDBx:U11>
         <PDBx:U12>-0.1809</PDBx:U12>
         <PDBx:U13>-0.0542</PDBx:U13>
         <PDBx:U22>0.4332</PDBx:U22>
         <PDBx:U23>-0.0491</PDBx:U23>
         <PDBx:U33>0.3823</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3363">
         <PDBx:U11>0.4930</PDBx:U11>
         <PDBx:U12>-0.1974</PDBx:U12>
         <PDBx:U13>-0.0463</PDBx:U13>
         <PDBx:U22>0.4053</PDBx:U22>
         <PDBx:U23>-0.0611</PDBx:U23>
         <PDBx:U33>0.3813</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3364">
         <PDBx:U11>0.4525</PDBx:U11>
         <PDBx:U12>-0.2008</PDBx:U12>
         <PDBx:U13>-0.0393</PDBx:U13>
         <PDBx:U22>0.3495</PDBx:U22>
         <PDBx:U23>-0.0571</PDBx:U23>
         <PDBx:U33>0.3553</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3365">
         <PDBx:U11>0.4687</PDBx:U11>
         <PDBx:U12>-0.2080</PDBx:U12>
         <PDBx:U13>-0.0469</PDBx:U13>
         <PDBx:U22>0.3660</PDBx:U22>
         <PDBx:U23>-0.0757</PDBx:U23>
         <PDBx:U33>0.3318</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>502</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>202</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3366">
         <PDBx:U11>0.2899</PDBx:U11>
         <PDBx:U12>-0.1460</PDBx:U12>
         <PDBx:U13>-0.0524</PDBx:U13>
         <PDBx:U22>0.3140</PDBx:U22>
         <PDBx:U23>-0.0047</PDBx:U23>
         <PDBx:U33>0.2639</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3367">
         <PDBx:U11>0.3008</PDBx:U11>
         <PDBx:U12>-0.1355</PDBx:U12>
         <PDBx:U13>-0.0455</PDBx:U13>
         <PDBx:U22>0.3297</PDBx:U22>
         <PDBx:U23>0.0063</PDBx:U23>
         <PDBx:U33>0.2910</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3368">
         <PDBx:U11>0.2950</PDBx:U11>
         <PDBx:U12>-0.1173</PDBx:U12>
         <PDBx:U13>-0.0478</PDBx:U13>
         <PDBx:U22>0.3460</PDBx:U22>
         <PDBx:U23>0.0127</PDBx:U23>
         <PDBx:U33>0.2909</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3369">
         <PDBx:U11>0.2536</PDBx:U11>
         <PDBx:U12>-0.1064</PDBx:U12>
         <PDBx:U13>-0.0413</PDBx:U13>
         <PDBx:U22>0.2941</PDBx:U22>
         <PDBx:U23>0.0174</PDBx:U23>
         <PDBx:U33>0.2515</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3370">
         <PDBx:U11>0.3213</PDBx:U11>
         <PDBx:U12>-0.1453</PDBx:U12>
         <PDBx:U13>-0.0444</PDBx:U13>
         <PDBx:U22>0.3741</PDBx:U22>
         <PDBx:U23>0.0119</PDBx:U23>
         <PDBx:U33>0.3299</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3371">
         <PDBx:U11>0.2746</PDBx:U11>
         <PDBx:U12>-0.1363</PDBx:U12>
         <PDBx:U13>-0.0363</PDBx:U13>
         <PDBx:U22>0.3298</PDBx:U22>
         <PDBx:U23>0.0230</PDBx:U23>
         <PDBx:U33>0.2945</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3372">
         <PDBx:U11>0.2964</PDBx:U11>
         <PDBx:U12>-0.1489</PDBx:U12>
         <PDBx:U13>-0.0334</PDBx:U13>
         <PDBx:U22>0.3712</PDBx:U22>
         <PDBx:U23>0.0276</PDBx:U23>
         <PDBx:U33>0.3295</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3373">
         <PDBx:U11>0.3051</PDBx:U11>
         <PDBx:U12>-0.1415</PDBx:U12>
         <PDBx:U13>-0.0256</PDBx:U13>
         <PDBx:U22>0.3804</PDBx:U22>
         <PDBx:U23>0.0384</PDBx:U23>
         <PDBx:U33>0.3435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3374">
         <PDBx:U11>0.3792</PDBx:U11>
         <PDBx:U12>-0.1439</PDBx:U12>
         <PDBx:U13>-0.0182</PDBx:U13>
         <PDBx:U22>0.4203</PDBx:U22>
         <PDBx:U23>0.0444</PDBx:U23>
         <PDBx:U33>0.4107</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3375">
         <PDBx:U11>0.4082</PDBx:U11>
         <PDBx:U12>-0.1521</PDBx:U12>
         <PDBx:U13>-0.0157</PDBx:U13>
         <PDBx:U22>0.4081</PDBx:U22>
         <PDBx:U23>0.0397</PDBx:U23>
         <PDBx:U33>0.4292</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3376">
         <PDBx:U11>0.4068</PDBx:U11>
         <PDBx:U12>-0.1370</PDBx:U12>
         <PDBx:U13>-0.0127</PDBx:U13>
         <PDBx:U22>0.4537</PDBx:U22>
         <PDBx:U23>0.0552</PDBx:U23>
         <PDBx:U33>0.4407</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>503</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>203</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3377">
         <PDBx:U11>0.2817</PDBx:U11>
         <PDBx:U12>-0.1132</PDBx:U12>
         <PDBx:U13>-0.0571</PDBx:U13>
         <PDBx:U22>0.3631</PDBx:U22>
         <PDBx:U23>0.0127</PDBx:U23>
         <PDBx:U33>0.2812</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3378">
         <PDBx:U11>0.3350</PDBx:U11>
         <PDBx:U12>-0.0944</PDBx:U12>
         <PDBx:U13>-0.0590</PDBx:U13>
         <PDBx:U22>0.4323</PDBx:U22>
         <PDBx:U23>0.0179</PDBx:U23>
         <PDBx:U33>0.3386</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3379">
         <PDBx:U11>0.2927</PDBx:U11>
         <PDBx:U12>-0.0889</PDBx:U12>
         <PDBx:U13>-0.0556</PDBx:U13>
         <PDBx:U22>0.3572</PDBx:U22>
         <PDBx:U23>0.0154</PDBx:U23>
         <PDBx:U33>0.2755</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3380">
         <PDBx:U11>0.3140</PDBx:U11>
         <PDBx:U12>-0.0774</PDBx:U12>
         <PDBx:U13>-0.0506</PDBx:U13>
         <PDBx:U22>0.3779</PDBx:U22>
         <PDBx:U23>0.0195</PDBx:U23>
         <PDBx:U33>0.3008</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3381">
         <PDBx:U11>0.3382</PDBx:U11>
         <PDBx:U12>-0.0881</PDBx:U12>
         <PDBx:U13>-0.0710</PDBx:U13>
         <PDBx:U22>0.4648</PDBx:U22>
         <PDBx:U23>0.0177</PDBx:U23>
         <PDBx:U33>0.3449</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3382">
         <PDBx:U11>0.2734</PDBx:U11>
         <PDBx:U12>-0.0656</PDBx:U12>
         <PDBx:U13>-0.0737</PDBx:U13>
         <PDBx:U22>0.4076</PDBx:U22>
         <PDBx:U23>0.0231</PDBx:U23>
         <PDBx:U33>0.2794</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3383">
         <PDBx:U11>0.2192</PDBx:U11>
         <PDBx:U12>-0.0537</PDBx:U12>
         <PDBx:U13>-0.0645</PDBx:U13>
         <PDBx:U22>0.3689</PDBx:U22>
         <PDBx:U23>0.0283</PDBx:U23>
         <PDBx:U33>0.2466</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3384">
         <PDBx:U11>0.2295</PDBx:U11>
         <PDBx:U12>-0.0569</PDBx:U12>
         <PDBx:U13>-0.0877</PDBx:U13>
         <PDBx:U22>0.3884</PDBx:U22>
         <PDBx:U23>0.0242</PDBx:U23>
         <PDBx:U33>0.2362</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>504</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>204</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3385">
         <PDBx:U11>0.3185</PDBx:U11>
         <PDBx:U12>-0.0981</PDBx:U12>
         <PDBx:U13>-0.0568</PDBx:U13>
         <PDBx:U22>0.3558</PDBx:U22>
         <PDBx:U23>0.0067</PDBx:U23>
         <PDBx:U33>0.2779</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>505</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3386">
         <PDBx:U11>0.2858</PDBx:U11>
         <PDBx:U12>-0.0943</PDBx:U12>
         <PDBx:U13>-0.0504</PDBx:U13>
         <PDBx:U22>0.2891</PDBx:U22>
         <PDBx:U23>0.0012</PDBx:U23>
         <PDBx:U33>0.2220</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>505</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3387">
         <PDBx:U11>0.3369</PDBx:U11>
         <PDBx:U12>-0.0923</PDBx:U12>
         <PDBx:U13>-0.0379</PDBx:U13>
         <PDBx:U22>0.3190</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.2818</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>505</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3388">
         <PDBx:U11>0.3287</PDBx:U11>
         <PDBx:U12>-0.0830</PDBx:U12>
         <PDBx:U13>-0.0308</PDBx:U13>
         <PDBx:U22>0.3014</PDBx:U22>
         <PDBx:U23>0.0009</PDBx:U23>
         <PDBx:U33>0.2713</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>505</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3389">
         <PDBx:U11>0.3198</PDBx:U11>
         <PDBx:U12>-0.1034</PDBx:U12>
         <PDBx:U13>-0.0507</PDBx:U13>
         <PDBx:U22>0.3001</PDBx:U22>
         <PDBx:U23>-0.0096</PDBx:U23>
         <PDBx:U33>0.2293</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>505</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>205</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3390">
         <PDBx:U11>0.3240</PDBx:U11>
         <PDBx:U12>-0.0991</PDBx:U12>
         <PDBx:U13>-0.0343</PDBx:U13>
         <PDBx:U22>0.2987</PDBx:U22>
         <PDBx:U23>0.0007</PDBx:U23>
         <PDBx:U33>0.2792</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3391">
         <PDBx:U11>0.3227</PDBx:U11>
         <PDBx:U12>-0.0934</PDBx:U12>
         <PDBx:U13>-0.0240</PDBx:U13>
         <PDBx:U22>0.2786</PDBx:U22>
         <PDBx:U23>0.0034</PDBx:U23>
         <PDBx:U33>0.2880</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3392">
         <PDBx:U11>0.3453</PDBx:U11>
         <PDBx:U12>-0.0831</PDBx:U12>
         <PDBx:U13>-0.0226</PDBx:U13>
         <PDBx:U22>0.3250</PDBx:U22>
         <PDBx:U23>0.0142</PDBx:U23>
         <PDBx:U33>0.3279</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3393">
         <PDBx:U11>0.2923</PDBx:U11>
         <PDBx:U12>-0.0744</PDBx:U12>
         <PDBx:U13>-0.0154</PDBx:U13>
         <PDBx:U22>0.2625</PDBx:U22>
         <PDBx:U23>0.0154</PDBx:U23>
         <PDBx:U33>0.2779</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3394">
         <PDBx:U11>0.3434</PDBx:U11>
         <PDBx:U12>-0.1030</PDBx:U12>
         <PDBx:U13>-0.0221</PDBx:U13>
         <PDBx:U22>0.2879</PDBx:U22>
         <PDBx:U23>0.0049</PDBx:U23>
         <PDBx:U33>0.3156</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3395">
         <PDBx:U11>0.3971</PDBx:U11>
         <PDBx:U12>-0.1131</PDBx:U12>
         <PDBx:U13>-0.0204</PDBx:U13>
         <PDBx:U22>0.3124</PDBx:U22>
         <PDBx:U23>-0.0078</PDBx:U23>
         <PDBx:U33>0.3529</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3396">
         <PDBx:U11>0.4202</PDBx:U11>
         <PDBx:U12>-0.1272</PDBx:U12>
         <PDBx:U13>-0.0200</PDBx:U13>
         <PDBx:U22>0.3276</PDBx:U22>
         <PDBx:U23>-0.0067</PDBx:U23>
         <PDBx:U33>0.3820</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3397">
         <PDBx:U11>0.4206</PDBx:U11>
         <PDBx:U12>-0.1291</PDBx:U12>
         <PDBx:U13>-0.0198</PDBx:U13>
         <PDBx:U22>0.3430</PDBx:U22>
         <PDBx:U23>0.0045</PDBx:U23>
         <PDBx:U33>0.3977</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3398">
         <PDBx:U11>0.4085</PDBx:U11>
         <PDBx:U12>-0.1384</PDBx:U12>
         <PDBx:U13>-0.0186</PDBx:U13>
         <PDBx:U22>0.2913</PDBx:U22>
         <PDBx:U23>-0.0189</PDBx:U23>
         <PDBx:U33>0.3559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>506</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>206</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3399">
         <PDBx:U11>0.2804</PDBx:U11>
         <PDBx:U12>-0.0832</PDBx:U12>
         <PDBx:U13>-0.0285</PDBx:U13>
         <PDBx:U22>0.2940</PDBx:U22>
         <PDBx:U23>0.0210</PDBx:U23>
         <PDBx:U33>0.2750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3400">
         <PDBx:U11>0.3001</PDBx:U11>
         <PDBx:U12>-0.0722</PDBx:U12>
         <PDBx:U13>-0.0255</PDBx:U13>
         <PDBx:U22>0.3380</PDBx:U22>
         <PDBx:U23>0.0286</PDBx:U23>
         <PDBx:U33>0.3088</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3401">
         <PDBx:U11>0.2408</PDBx:U11>
         <PDBx:U12>-0.0627</PDBx:U12>
         <PDBx:U13>-0.0235</PDBx:U13>
         <PDBx:U22>0.2807</PDBx:U22>
         <PDBx:U23>0.0258</PDBx:U23>
         <PDBx:U33>0.2449</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3402">
         <PDBx:U11>0.2213</PDBx:U11>
         <PDBx:U12>-0.0538</PDBx:U12>
         <PDBx:U13>-0.0162</PDBx:U13>
         <PDBx:U22>0.2636</PDBx:U22>
         <PDBx:U23>0.0269</PDBx:U23>
         <PDBx:U33>0.2302</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3403">
         <PDBx:U11>0.2735</PDBx:U11>
         <PDBx:U12>-0.0720</PDBx:U12>
         <PDBx:U13>-0.0287</PDBx:U13>
         <PDBx:U22>0.3438</PDBx:U22>
         <PDBx:U23>0.0330</PDBx:U23>
         <PDBx:U33>0.2940</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3404">
         <PDBx:U11>0.3124</PDBx:U11>
         <PDBx:U12>-0.0829</PDBx:U12>
         <PDBx:U13>-0.0277</PDBx:U13>
         <PDBx:U22>0.3847</PDBx:U22>
         <PDBx:U23>0.0367</PDBx:U23>
         <PDBx:U33>0.3385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3405">
         <PDBx:U11>0.2910</PDBx:U11>
         <PDBx:U12>-0.0827</PDBx:U12>
         <PDBx:U13>-0.0287</PDBx:U13>
         <PDBx:U22>0.3984</PDBx:U22>
         <PDBx:U23>0.0388</PDBx:U23>
         <PDBx:U33>0.3296</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3406">
         <PDBx:U11>0.2888</PDBx:U11>
         <PDBx:U12>-0.0804</PDBx:U12>
         <PDBx:U13>-0.0212</PDBx:U13>
         <PDBx:U22>0.3479</PDBx:U22>
         <PDBx:U23>0.0433</PDBx:U23>
         <PDBx:U33>0.3156</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>507</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>207</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3407">
         <PDBx:U11>0.2075</PDBx:U11>
         <PDBx:U12>-0.0609</PDBx:U12>
         <PDBx:U13>-0.0287</PDBx:U13>
         <PDBx:U22>0.2433</PDBx:U22>
         <PDBx:U23>0.0211</PDBx:U23>
         <PDBx:U33>0.1975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3408">
         <PDBx:U11>0.2223</PDBx:U11>
         <PDBx:U12>-0.0484</PDBx:U12>
         <PDBx:U13>-0.0239</PDBx:U13>
         <PDBx:U22>0.2495</PDBx:U22>
         <PDBx:U23>0.0186</PDBx:U23>
         <PDBx:U33>0.2003</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3409">
         <PDBx:U11>0.2566</PDBx:U11>
         <PDBx:U12>-0.0477</PDBx:U12>
         <PDBx:U13>-0.0131</PDBx:U13>
         <PDBx:U22>0.2557</PDBx:U22>
         <PDBx:U23>0.0112</PDBx:U23>
         <PDBx:U33>0.2222</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3410">
         <PDBx:U11>0.2819</PDBx:U11>
         <PDBx:U12>-0.0409</PDBx:U12>
         <PDBx:U13>-0.0048</PDBx:U13>
         <PDBx:U22>0.2777</PDBx:U22>
         <PDBx:U23>0.0089</PDBx:U23>
         <PDBx:U33>0.2452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3411">
         <PDBx:U11>0.2580</PDBx:U11>
         <PDBx:U12>-0.0456</PDBx:U12>
         <PDBx:U13>-0.0334</PDBx:U13>
         <PDBx:U22>0.2858</PDBx:U22>
         <PDBx:U23>0.0194</PDBx:U23>
         <PDBx:U33>0.2199</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3412">
         <PDBx:U11>0.2945</PDBx:U11>
         <PDBx:U12>-0.0415</PDBx:U12>
         <PDBx:U13>-0.0443</PDBx:U13>
         <PDBx:U22>0.3600</PDBx:U22>
         <PDBx:U23>0.0264</PDBx:U23>
         <PDBx:U33>0.2746</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3413">
         <PDBx:U11>0.3429</PDBx:U11>
         <PDBx:U12>-0.0337</PDBx:U12>
         <PDBx:U13>-0.0558</PDBx:U13>
         <PDBx:U22>0.4105</PDBx:U22>
         <PDBx:U23>0.0298</PDBx:U23>
         <PDBx:U33>0.3065</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3414">
         <PDBx:U11>0.2468</PDBx:U11>
         <PDBx:U12>-0.0294</PDBx:U12>
         <PDBx:U13>-0.0365</PDBx:U13>
         <PDBx:U22>0.3306</PDBx:U22>
         <PDBx:U23>0.0296</PDBx:U23>
         <PDBx:U33>0.2461</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>508</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>208</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3415">
         <PDBx:U11>0.2738</PDBx:U11>
         <PDBx:U12>-0.0557</PDBx:U12>
         <PDBx:U13>-0.0119</PDBx:U13>
         <PDBx:U22>0.2534</PDBx:U22>
         <PDBx:U23>0.0059</PDBx:U23>
         <PDBx:U33>0.2327</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3416">
         <PDBx:U11>0.3113</PDBx:U11>
         <PDBx:U12>-0.0531</PDBx:U12>
         <PDBx:U13>-0.0001</PDBx:U13>
         <PDBx:U22>0.2701</PDBx:U22>
         <PDBx:U23>-0.0024</PDBx:U23>
         <PDBx:U33>0.2641</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3417">
         <PDBx:U11>0.2875</PDBx:U11>
         <PDBx:U12>-0.0455</PDBx:U12>
         <PDBx:U13>0.0060</PDBx:U13>
         <PDBx:U22>0.2599</PDBx:U22>
         <PDBx:U23>0.0010</PDBx:U23>
         <PDBx:U33>0.2627</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3418">
         <PDBx:U11>0.2692</PDBx:U11>
         <PDBx:U12>-0.0405</PDBx:U12>
         <PDBx:U13>0.0155</PDBx:U13>
         <PDBx:U22>0.2410</PDBx:U22>
         <PDBx:U23>-0.0049</PDBx:U23>
         <PDBx:U33>0.2467</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3419">
         <PDBx:U11>0.2945</PDBx:U11>
         <PDBx:U12>-0.0612</PDBx:U12>
         <PDBx:U13>0.0015</PDBx:U13>
         <PDBx:U22>0.2273</PDBx:U22>
         <PDBx:U23>-0.0106</PDBx:U23>
         <PDBx:U33>0.2357</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3420">
         <PDBx:U11>0.2923</PDBx:U11>
         <PDBx:U12>-0.0698</PDBx:U12>
         <PDBx:U13>-0.0015</PDBx:U13>
         <PDBx:U22>0.2089</PDBx:U22>
         <PDBx:U23>-0.0185</PDBx:U23>
         <PDBx:U33>0.2027</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3421">
         <PDBx:U11>0.3756</PDBx:U11>
         <PDBx:U12>-0.0735</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>0.2704</PDBx:U22>
         <PDBx:U23>-0.0285</PDBx:U23>
         <PDBx:U33>0.2780</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3422">
         <PDBx:U11>0.3695</PDBx:U11>
         <PDBx:U12>-0.0645</PDBx:U12>
         <PDBx:U13>0.0066</PDBx:U13>
         <PDBx:U22>0.2809</PDBx:U22>
         <PDBx:U23>-0.0211</PDBx:U23>
         <PDBx:U33>0.2624</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>509</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>209</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3423">
         <PDBx:U11>0.2814</PDBx:U11>
         <PDBx:U12>-0.0460</PDBx:U12>
         <PDBx:U13>0.0002</PDBx:U13>
         <PDBx:U22>0.2697</PDBx:U22>
         <PDBx:U23>0.0107</PDBx:U23>
         <PDBx:U33>0.2723</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3424">
         <PDBx:U11>0.2056</PDBx:U11>
         <PDBx:U12>-0.0390</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.2110</PDBx:U22>
         <PDBx:U23>0.0166</PDBx:U23>
         <PDBx:U33>0.2137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3425">
         <PDBx:U11>0.2765</PDBx:U11>
         <PDBx:U12>-0.0349</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.3029</PDBx:U22>
         <PDBx:U23>0.0138</PDBx:U23>
         <PDBx:U33>0.2868</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3426">
         <PDBx:U11>0.1781</PDBx:U11>
         <PDBx:U12>-0.0304</PDBx:U12>
         <PDBx:U13>0.0102</PDBx:U13>
         <PDBx:U22>0.2193</PDBx:U22>
         <PDBx:U23>0.0127</PDBx:U23>
         <PDBx:U33>0.1981</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3427">
         <PDBx:U11>0.2880</PDBx:U11>
         <PDBx:U12>-0.0431</PDBx:U12>
         <PDBx:U13>-0.0031</PDBx:U13>
         <PDBx:U22>0.3039</PDBx:U22>
         <PDBx:U23>0.0295</PDBx:U23>
         <PDBx:U33>0.3057</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3428">
         <PDBx:U11>0.3198</PDBx:U11>
         <PDBx:U12>-0.0502</PDBx:U12>
         <PDBx:U13>-0.0043</PDBx:U13>
         <PDBx:U22>0.3062</PDBx:U22>
         <PDBx:U23>0.0311</PDBx:U23>
         <PDBx:U33>0.3329</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3429">
         <PDBx:U11>0.3236</PDBx:U11>
         <PDBx:U12>-0.0355</PDBx:U12>
         <PDBx:U13>-0.0020</PDBx:U13>
         <PDBx:U22>0.3593</PDBx:U22>
         <PDBx:U23>0.0377</PDBx:U23>
         <PDBx:U33>0.3530</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3430">
         <PDBx:U11>0.3769</PDBx:U11>
         <PDBx:U12>-0.0593</PDBx:U12>
         <PDBx:U13>-0.0082</PDBx:U13>
         <PDBx:U22>0.3674</PDBx:U22>
         <PDBx:U23>0.0445</PDBx:U23>
         <PDBx:U33>0.3956</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>510</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>210</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3431">
         <PDBx:U11>0.2081</PDBx:U11>
         <PDBx:U12>-0.0363</PDBx:U12>
         <PDBx:U13>0.0046</PDBx:U13>
         <PDBx:U22>0.2356</PDBx:U22>
         <PDBx:U23>0.0123</PDBx:U23>
         <PDBx:U33>0.2091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3432">
         <PDBx:U11>0.2534</PDBx:U11>
         <PDBx:U12>-0.0330</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.2894</PDBx:U22>
         <PDBx:U23>0.0079</PDBx:U23>
         <PDBx:U33>0.2519</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3433">
         <PDBx:U11>0.2526</PDBx:U11>
         <PDBx:U12>-0.0345</PDBx:U12>
         <PDBx:U13>0.0201</PDBx:U13>
         <PDBx:U22>0.2760</PDBx:U22>
         <PDBx:U23>-0.0021</PDBx:U23>
         <PDBx:U33>0.2436</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3434">
         <PDBx:U11>0.2552</PDBx:U11>
         <PDBx:U12>-0.0348</PDBx:U12>
         <PDBx:U13>0.0256</PDBx:U13>
         <PDBx:U22>0.2881</PDBx:U22>
         <PDBx:U23>-0.0077</PDBx:U23>
         <PDBx:U33>0.2493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3435">
         <PDBx:U11>0.3310</PDBx:U11>
         <PDBx:U12>-0.0298</PDBx:U12>
         <PDBx:U13>0.0068</PDBx:U13>
         <PDBx:U22>0.3632</PDBx:U22>
         <PDBx:U23>0.0096</PDBx:U23>
         <PDBx:U33>0.3202</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3436">
         <PDBx:U11>0.3817</PDBx:U11>
         <PDBx:U12>-0.0259</PDBx:U12>
         <PDBx:U13>0.0043</PDBx:U13>
         <PDBx:U22>0.4402</PDBx:U22>
         <PDBx:U23>0.0143</PDBx:U23>
         <PDBx:U33>0.3839</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3437">
         <PDBx:U11>0.3518</PDBx:U11>
         <PDBx:U12>-0.0316</PDBx:U12>
         <PDBx:U13>-0.0007</PDBx:U13>
         <PDBx:U22>0.4306</PDBx:U22>
         <PDBx:U23>0.0220</PDBx:U23>
         <PDBx:U33>0.3689</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>211</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3438">
         <PDBx:U11>0.2736</PDBx:U11>
         <PDBx:U12>-0.0185</PDBx:U12>
         <PDBx:U13>-0.0010</PDBx:U13>
         <PDBx:U22>0.3327</PDBx:U22>
         <PDBx:U23>0.0174</PDBx:U23>
         <PDBx:U33>0.2721</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>511</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
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         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
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         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0264</PDBx:U23>
         <PDBx:U33>0.2150</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U23>-0.0205</PDBx:U23>
         <PDBx:U33>0.2568</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0206</PDBx:U23>
         <PDBx:U33>0.2563</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U13>0.0513</PDBx:U13>
         <PDBx:U22>0.2563</PDBx:U22>
         <PDBx:U23>-0.0309</PDBx:U23>
         <PDBx:U33>0.2455</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.3432</PDBx:U11>
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         <PDBx:U13>0.0360</PDBx:U13>
         <PDBx:U22>0.2904</PDBx:U22>
         <PDBx:U23>-0.0177</PDBx:U23>
         <PDBx:U33>0.2711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>512</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>212</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.2282</PDBx:U11>
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         <PDBx:U22>0.2566</PDBx:U22>
         <PDBx:U23>-0.0116</PDBx:U23>
         <PDBx:U33>0.2416</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U13>0.0305</PDBx:U13>
         <PDBx:U22>0.2534</PDBx:U22>
         <PDBx:U23>-0.0103</PDBx:U23>
         <PDBx:U33>0.2361</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0072</PDBx:U23>
         <PDBx:U33>0.1711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U23>-0.0099</PDBx:U23>
         <PDBx:U33>0.2807</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U13>0.0246</PDBx:U13>
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         <PDBx:U23>-0.0005</PDBx:U23>
         <PDBx:U33>0.2833</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.3588</PDBx:U11>
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         <PDBx:U22>0.3700</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.3946</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.5323</PDBx:U11>
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         <PDBx:U22>0.5131</PDBx:U22>
         <PDBx:U23>-0.0080</PDBx:U23>
         <PDBx:U33>0.5486</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3455">
         <PDBx:U11>0.4160</PDBx:U11>
         <PDBx:U12>-0.0066</PDBx:U12>
         <PDBx:U13>0.0418</PDBx:U13>
         <PDBx:U22>0.4247</PDBx:U22>
         <PDBx:U23>-0.0180</PDBx:U23>
         <PDBx:U33>0.4601</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3456">
         <PDBx:U11>0.5532</PDBx:U11>
         <PDBx:U12>-0.0201</PDBx:U12>
         <PDBx:U13>0.0370</PDBx:U13>
         <PDBx:U22>0.5097</PDBx:U22>
         <PDBx:U23>-0.0184</PDBx:U23>
         <PDBx:U33>0.5618</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3457">
         <PDBx:U11>0.5246</PDBx:U11>
         <PDBx:U12>-0.0101</PDBx:U12>
         <PDBx:U13>0.0463</PDBx:U13>
         <PDBx:U22>0.4966</PDBx:U22>
         <PDBx:U23>-0.0247</PDBx:U23>
         <PDBx:U33>0.5504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>513</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>213</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3458">
         <PDBx:U11>0.1826</PDBx:U11>
         <PDBx:U12>-0.0269</PDBx:U12>
         <PDBx:U13>0.0200</PDBx:U13>
         <PDBx:U22>0.2622</PDBx:U22>
         <PDBx:U23>-0.0014</PDBx:U23>
         <PDBx:U33>0.2166</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3459">
         <PDBx:U11>0.2038</PDBx:U11>
         <PDBx:U12>-0.0260</PDBx:U12>
         <PDBx:U13>0.0154</PDBx:U13>
         <PDBx:U22>0.2952</PDBx:U22>
         <PDBx:U23>-0.0018</PDBx:U23>
         <PDBx:U33>0.2340</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3460">
         <PDBx:U11>0.2154</PDBx:U11>
         <PDBx:U12>-0.0310</PDBx:U12>
         <PDBx:U13>0.0207</PDBx:U13>
         <PDBx:U22>0.3009</PDBx:U22>
         <PDBx:U23>-0.0145</PDBx:U23>
         <PDBx:U33>0.2367</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3461">
         <PDBx:U11>0.1948</PDBx:U11>
         <PDBx:U12>-0.0337</PDBx:U12>
         <PDBx:U13>0.0191</PDBx:U13>
         <PDBx:U22>0.2967</PDBx:U22>
         <PDBx:U23>-0.0195</PDBx:U23>
         <PDBx:U33>0.2165</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3462">
         <PDBx:U11>0.1812</PDBx:U11>
         <PDBx:U12>-0.0260</PDBx:U12>
         <PDBx:U13>0.0112</PDBx:U13>
         <PDBx:U22>0.2693</PDBx:U22>
         <PDBx:U23>0.0042</PDBx:U23>
         <PDBx:U33>0.2035</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3463">
         <PDBx:U11>0.2341</PDBx:U11>
         <PDBx:U12>-0.0246</PDBx:U12>
         <PDBx:U13>0.0051</PDBx:U13>
         <PDBx:U22>0.3295</PDBx:U22>
         <PDBx:U23>0.0183</PDBx:U23>
         <PDBx:U33>0.2631</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3464">
         <PDBx:U11>0.2006</PDBx:U11>
         <PDBx:U12>-0.0273</PDBx:U12>
         <PDBx:U13>0.0107</PDBx:U13>
         <PDBx:U22>0.2995</PDBx:U22>
         <PDBx:U23>-0.0008</PDBx:U23>
         <PDBx:U33>0.2160</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3465">
         <PDBx:U11>0.2812</PDBx:U11>
         <PDBx:U12>-0.0259</PDBx:U12>
         <PDBx:U13>0.0018</PDBx:U13>
         <PDBx:U22>0.3760</PDBx:U22>
         <PDBx:U23>0.0235</PDBx:U23>
         <PDBx:U33>0.3041</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>514</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>214</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3466">
         <PDBx:U11>0.2236</PDBx:U11>
         <PDBx:U12>-0.0347</PDBx:U12>
         <PDBx:U13>0.0268</PDBx:U13>
         <PDBx:U22>0.2860</PDBx:U22>
         <PDBx:U23>-0.0199</PDBx:U23>
         <PDBx:U33>0.2342</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3467">
         <PDBx:U11>0.2820</PDBx:U11>
         <PDBx:U12>-0.0426</PDBx:U12>
         <PDBx:U13>0.0331</PDBx:U13>
         <PDBx:U22>0.3332</PDBx:U22>
         <PDBx:U23>-0.0314</PDBx:U23>
         <PDBx:U33>0.2837</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3468">
         <PDBx:U11>0.1734</PDBx:U11>
         <PDBx:U12>-0.0454</PDBx:U12>
         <PDBx:U13>0.0350</PDBx:U13>
         <PDBx:U22>0.2413</PDBx:U22>
         <PDBx:U23>-0.0380</PDBx:U23>
         <PDBx:U33>0.1852</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3469">
         <PDBx:U11>0.2414</PDBx:U11>
         <PDBx:U12>-0.0529</PDBx:U12>
         <PDBx:U13>0.0363</PDBx:U13>
         <PDBx:U22>0.3208</PDBx:U22>
         <PDBx:U23>-0.0472</PDBx:U23>
         <PDBx:U33>0.2529</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3470">
         <PDBx:U11>0.2834</PDBx:U11>
         <PDBx:U12>-0.0459</PDBx:U12>
         <PDBx:U13>0.0396</PDBx:U13>
         <PDBx:U22>0.3029</PDBx:U22>
         <PDBx:U23>-0.0326</PDBx:U23>
         <PDBx:U33>0.2695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3471">
         <PDBx:U11>0.3202</PDBx:U11>
         <PDBx:U12>-0.0569</PDBx:U12>
         <PDBx:U13>0.0481</PDBx:U13>
         <PDBx:U22>0.3211</PDBx:U22>
         <PDBx:U23>-0.0424</PDBx:U23>
         <PDBx:U33>0.2958</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3472">
         <PDBx:U11>0.3099</PDBx:U11>
         <PDBx:U12>-0.0609</PDBx:U12>
         <PDBx:U13>0.0515</PDBx:U13>
         <PDBx:U22>0.3013</PDBx:U22>
         <PDBx:U23>-0.0449</PDBx:U23>
         <PDBx:U33>0.2789</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3473">
         <PDBx:U11>0.4507</PDBx:U11>
         <PDBx:U12>-0.0512</PDBx:U12>
         <PDBx:U13>0.0512</PDBx:U13>
         <PDBx:U22>0.4277</PDBx:U22>
         <PDBx:U23>-0.0351</PDBx:U23>
         <PDBx:U33>0.4095</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3474">
         <PDBx:U11>0.5065</PDBx:U11>
         <PDBx:U12>-0.0501</PDBx:U12>
         <PDBx:U13>0.0597</PDBx:U13>
         <PDBx:U22>0.4490</PDBx:U22>
         <PDBx:U23>-0.0327</PDBx:U23>
         <PDBx:U33>0.4437</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3475">
         <PDBx:U11>0.4979</PDBx:U11>
         <PDBx:U12>-0.0618</PDBx:U12>
         <PDBx:U13>0.0709</PDBx:U13>
         <PDBx:U22>0.4125</PDBx:U22>
         <PDBx:U23>-0.0372</PDBx:U23>
         <PDBx:U33>0.4217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3476">
         <PDBx:U11>0.6421</PDBx:U11>
         <PDBx:U12>-0.0372</PDBx:U12>
         <PDBx:U13>0.0583</PDBx:U13>
         <PDBx:U22>0.5762</PDBx:U22>
         <PDBx:U23>-0.0251</PDBx:U23>
         <PDBx:U33>0.5677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>515</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>215</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3477">
         <PDBx:U11>0.1604</PDBx:U11>
         <PDBx:U12>-0.0402</PDBx:U12>
         <PDBx:U13>0.0367</PDBx:U13>
         <PDBx:U22>0.2319</PDBx:U22>
         <PDBx:U23>-0.0347</PDBx:U23>
         <PDBx:U33>0.1822</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3478">
         <PDBx:U11>0.2539</PDBx:U11>
         <PDBx:U12>-0.0400</PDBx:U12>
         <PDBx:U13>0.0402</PDBx:U13>
         <PDBx:U22>0.3458</PDBx:U22>
         <PDBx:U23>-0.0402</PDBx:U23>
         <PDBx:U33>0.2909</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3479">
         <PDBx:U11>0.1954</PDBx:U11>
         <PDBx:U12>-0.0369</PDBx:U12>
         <PDBx:U13>0.0330</PDBx:U13>
         <PDBx:U22>0.3217</PDBx:U22>
         <PDBx:U23>-0.0380</PDBx:U23>
         <PDBx:U33>0.2470</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3480">
         <PDBx:U11>0.2022</PDBx:U11>
         <PDBx:U12>-0.0431</PDBx:U12>
         <PDBx:U13>0.0344</PDBx:U13>
         <PDBx:U22>0.3475</PDBx:U22>
         <PDBx:U23>-0.0469</PDBx:U23>
         <PDBx:U33>0.2584</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3481">
         <PDBx:U11>0.2509</PDBx:U11>
         <PDBx:U12>-0.0319</PDBx:U12>
         <PDBx:U13>0.0448</PDBx:U13>
         <PDBx:U22>0.3427</PDBx:U22>
         <PDBx:U23>-0.0374</PDBx:U23>
         <PDBx:U33>0.2997</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3482">
         <PDBx:U11>0.2935</PDBx:U11>
         <PDBx:U12>-0.0286</PDBx:U12>
         <PDBx:U13>0.0503</PDBx:U13>
         <PDBx:U22>0.4079</PDBx:U22>
         <PDBx:U23>-0.0436</PDBx:U23>
         <PDBx:U33>0.3615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3483">
         <PDBx:U11>0.3450</PDBx:U11>
         <PDBx:U12>-0.0381</PDBx:U12>
         <PDBx:U13>0.0590</PDBx:U13>
         <PDBx:U22>0.4527</PDBx:U22>
         <PDBx:U23>-0.0546</PDBx:U23>
         <PDBx:U33>0.4063</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3484">
         <PDBx:U11>0.3260</PDBx:U11>
         <PDBx:U12>-0.0156</PDBx:U12>
         <PDBx:U13>0.0484</PDBx:U13>
         <PDBx:U22>0.4719</PDBx:U22>
         <PDBx:U23>-0.0395</PDBx:U23>
         <PDBx:U33>0.4221</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3485">
         <PDBx:U11>0.3582</PDBx:U11>
         <PDBx:U12>-0.0319</PDBx:U12>
         <PDBx:U13>0.0630</PDBx:U13>
         <PDBx:U22>0.4951</PDBx:U22>
         <PDBx:U23>-0.0580</PDBx:U23>
         <PDBx:U33>0.4430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3486">
         <PDBx:U11>0.3628</PDBx:U11>
         <PDBx:U12>-0.0165</PDBx:U12>
         <PDBx:U13>0.0563</PDBx:U13>
         <PDBx:U22>0.5230</PDBx:U22>
         <PDBx:U23>-0.0486</PDBx:U23>
         <PDBx:U33>0.4699</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>516</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>216</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3487">
         <PDBx:U11>0.1190</PDBx:U11>
         <PDBx:U12>-0.0289</PDBx:U12>
         <PDBx:U13>0.0251</PDBx:U13>
         <PDBx:U22>0.2547</PDBx:U22>
         <PDBx:U23>-0.0265</PDBx:U23>
         <PDBx:U33>0.1764</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3488">
         <PDBx:U11>0.1642</PDBx:U11>
         <PDBx:U12>-0.0257</PDBx:U12>
         <PDBx:U13>0.0167</PDBx:U13>
         <PDBx:U22>0.3316</PDBx:U22>
         <PDBx:U23>-0.0224</PDBx:U23>
         <PDBx:U33>0.2302</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3489">
         <PDBx:U11>0.1834</PDBx:U11>
         <PDBx:U12>-0.0374</PDBx:U12>
         <PDBx:U13>0.0166</PDBx:U13>
         <PDBx:U22>0.3575</PDBx:U22>
         <PDBx:U23>-0.0329</PDBx:U23>
         <PDBx:U33>0.2328</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3490">
         <PDBx:U11>0.1844</PDBx:U11>
         <PDBx:U12>-0.0407</PDBx:U12>
         <PDBx:U13>0.0143</PDBx:U13>
         <PDBx:U22>0.3883</PDBx:U22>
         <PDBx:U23>-0.0382</PDBx:U23>
         <PDBx:U33>0.2394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3491">
         <PDBx:U11>0.1679</PDBx:U11>
         <PDBx:U12>-0.0175</PDBx:U12>
         <PDBx:U13>0.0086</PDBx:U13>
         <PDBx:U22>0.3386</PDBx:U22>
         <PDBx:U23>-0.0073</PDBx:U23>
         <PDBx:U33>0.2352</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3492">
         <PDBx:U11>0.1823</PDBx:U11>
         <PDBx:U12>-0.0048</PDBx:U12>
         <PDBx:U13>0.0075</PDBx:U13>
         <PDBx:U22>0.3548</PDBx:U22>
         <PDBx:U23>0.0028</PDBx:U23>
         <PDBx:U33>0.2695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3493">
         <PDBx:U11>0.2055</PDBx:U11>
         <PDBx:U12>0.0039</PDBx:U12>
         <PDBx:U13>-0.0036</PDBx:U13>
         <PDBx:U22>0.3827</PDBx:U22>
         <PDBx:U23>0.0259</PDBx:U23>
         <PDBx:U33>0.2913</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3494">
         <PDBx:U11>0.2115</PDBx:U11>
         <PDBx:U12>-0.0087</PDBx:U12>
         <PDBx:U13>-0.0002</PDBx:U13>
         <PDBx:U22>0.3611</PDBx:U22>
         <PDBx:U23>0.0254</PDBx:U23>
         <PDBx:U33>0.2762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>517</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>217</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3495">
         <PDBx:U11>0.1595</PDBx:U11>
         <PDBx:U12>-0.0437</PDBx:U12>
         <PDBx:U13>0.0196</PDBx:U13>
         <PDBx:U22>0.3087</PDBx:U22>
         <PDBx:U23>-0.0371</PDBx:U23>
         <PDBx:U33>0.1903</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3496">
         <PDBx:U11>0.2204</PDBx:U11>
         <PDBx:U12>-0.0559</PDBx:U12>
         <PDBx:U13>0.0222</PDBx:U13>
         <PDBx:U22>0.3728</PDBx:U22>
         <PDBx:U23>-0.0505</PDBx:U23>
         <PDBx:U33>0.2361</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3497">
         <PDBx:U11>0.2232</PDBx:U11>
         <PDBx:U12>-0.0679</PDBx:U12>
         <PDBx:U13>0.0298</PDBx:U13>
         <PDBx:U22>0.3785</PDBx:U22>
         <PDBx:U23>-0.0662</PDBx:U23>
         <PDBx:U33>0.2381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3498">
         <PDBx:U11>0.2427</PDBx:U11>
         <PDBx:U12>-0.0773</PDBx:U12>
         <PDBx:U13>0.0309</PDBx:U13>
         <PDBx:U22>0.4231</PDBx:U22>
         <PDBx:U23>-0.0769</PDBx:U23>
         <PDBx:U33>0.2542</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3499">
         <PDBx:U11>0.2388</PDBx:U11>
         <PDBx:U12>-0.0589</PDBx:U12>
         <PDBx:U13>0.0254</PDBx:U13>
         <PDBx:U22>0.3617</PDBx:U22>
         <PDBx:U23>-0.0525</PDBx:U23>
         <PDBx:U33>0.2421</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3500">
         <PDBx:U11>0.2687</PDBx:U11>
         <PDBx:U12>-0.0720</PDBx:U12>
         <PDBx:U13>0.0309</PDBx:U13>
         <PDBx:U22>0.3885</PDBx:U22>
         <PDBx:U23>-0.0667</PDBx:U23>
         <PDBx:U33>0.2633</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>518</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>218</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.2367</PDBx:U11>
         <PDBx:U12>-0.0692</PDBx:U12>
         <PDBx:U13>0.0362</PDBx:U13>
         <PDBx:U22>0.3679</PDBx:U22>
         <PDBx:U23>-0.0681</PDBx:U23>
         <PDBx:U33>0.2525</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.2740</PDBx:U11>
         <PDBx:U12>-0.0823</PDBx:U12>
         <PDBx:U13>0.0454</PDBx:U13>
         <PDBx:U22>0.4052</PDBx:U22>
         <PDBx:U23>-0.0827</PDBx:U23>
         <PDBx:U33>0.2877</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3503">
         <PDBx:U11>0.2361</PDBx:U11>
         <PDBx:U12>-0.0821</PDBx:U12>
         <PDBx:U13>0.0426</PDBx:U13>
         <PDBx:U22>0.4117</PDBx:U22>
         <PDBx:U23>-0.0854</PDBx:U23>
         <PDBx:U33>0.2688</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3504">
         <PDBx:U11>0.3021</PDBx:U11>
         <PDBx:U12>-0.0959</PDBx:U12>
         <PDBx:U13>0.0473</PDBx:U13>
         <PDBx:U22>0.4959</PDBx:U22>
         <PDBx:U23>-0.0997</PDBx:U23>
         <PDBx:U33>0.3313</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3505">
         <PDBx:U11>0.3503</PDBx:U11>
         <PDBx:U12>-0.0826</PDBx:U12>
         <PDBx:U13>0.0526</PDBx:U13>
         <PDBx:U22>0.4505</PDBx:U22>
         <PDBx:U23>-0.0814</PDBx:U23>
         <PDBx:U33>0.3608</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3506">
         <PDBx:U11>0.3676</PDBx:U11>
         <PDBx:U12>-0.0859</PDBx:U12>
         <PDBx:U13>0.0572</PDBx:U13>
         <PDBx:U22>0.4245</PDBx:U22>
         <PDBx:U23>-0.0795</PDBx:U23>
         <PDBx:U33>0.3585</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3507">
         <PDBx:U11>0.4360</PDBx:U11>
         <PDBx:U12>-0.0811</PDBx:U12>
         <PDBx:U13>0.0588</PDBx:U13>
         <PDBx:U22>0.4691</PDBx:U22>
         <PDBx:U23>-0.0721</PDBx:U23>
         <PDBx:U33>0.4220</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3508">
         <PDBx:U11>0.4556</PDBx:U11>
         <PDBx:U12>-0.0904</PDBx:U12>
         <PDBx:U13>0.0599</PDBx:U13>
         <PDBx:U22>0.5042</PDBx:U22>
         <PDBx:U23>-0.0805</PDBx:U23>
         <PDBx:U33>0.4391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>519</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>219</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3509">
         <PDBx:U11>0.2337</PDBx:U11>
         <PDBx:U12>-0.0666</PDBx:U12>
         <PDBx:U13>0.0360</PDBx:U13>
         <PDBx:U22>0.4276</PDBx:U22>
         <PDBx:U23>-0.0722</PDBx:U23>
         <PDBx:U33>0.2879</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3510">
         <PDBx:U11>0.2980</PDBx:U11>
         <PDBx:U12>-0.0624</PDBx:U12>
         <PDBx:U13>0.0321</PDBx:U13>
         <PDBx:U22>0.5367</PDBx:U22>
         <PDBx:U23>-0.0722</PDBx:U23>
         <PDBx:U33>0.3768</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3511">
         <PDBx:U11>0.2856</PDBx:U11>
         <PDBx:U12>-0.0649</PDBx:U12>
         <PDBx:U13>0.0235</PDBx:U13>
         <PDBx:U22>0.5579</PDBx:U22>
         <PDBx:U23>-0.0726</PDBx:U23>
         <PDBx:U33>0.3621</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3512">
         <PDBx:U11>0.2642</PDBx:U11>
         <PDBx:U12>-0.0723</PDBx:U12>
         <PDBx:U13>0.0229</PDBx:U13>
         <PDBx:U22>0.5734</PDBx:U22>
         <PDBx:U23>-0.0816</PDBx:U23>
         <PDBx:U33>0.3501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3513">
         <PDBx:U11>0.2678</PDBx:U11>
         <PDBx:U12>-0.0430</PDBx:U12>
         <PDBx:U13>0.0285</PDBx:U13>
         <PDBx:U22>0.5142</PDBx:U22>
         <PDBx:U23>-0.0578</PDBx:U23>
         <PDBx:U33>0.3711</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3514">
         <PDBx:U11>0.3192</PDBx:U11>
         <PDBx:U12>-0.0411</PDBx:U12>
         <PDBx:U13>0.0392</PDBx:U13>
         <PDBx:U22>0.5392</PDBx:U22>
         <PDBx:U23>-0.0593</PDBx:U23>
         <PDBx:U33>0.4241</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3515">
         <PDBx:U11>0.3851</PDBx:U11>
         <PDBx:U12>-0.0527</PDBx:U12>
         <PDBx:U13>0.0493</PDBx:U13>
         <PDBx:U22>0.6163</PDBx:U22>
         <PDBx:U23>-0.0738</PDBx:U23>
         <PDBx:U33>0.4949</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3516">
         <PDBx:U11>0.4809</PDBx:U11>
         <PDBx:U12>-0.0443</PDBx:U12>
         <PDBx:U13>0.0468</PDBx:U13>
         <PDBx:U22>0.7627</PDBx:U22>
         <PDBx:U23>-0.0741</PDBx:U23>
         <PDBx:U33>0.6245</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3517">
         <PDBx:U11>0.5670</PDBx:U11>
         <PDBx:U12>-0.0548</PDBx:U12>
         <PDBx:U13>0.0589</PDBx:U13>
         <PDBx:U22>0.8621</PDBx:U22>
         <PDBx:U23>-0.0879</PDBx:U23>
         <PDBx:U33>0.7194</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>520</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>220</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3518">
         <PDBx:U11>0.2208</PDBx:U11>
         <PDBx:U12>-0.0598</PDBx:U12>
         <PDBx:U13>0.0175</PDBx:U13>
         <PDBx:U22>0.4834</PDBx:U22>
         <PDBx:U23>-0.0632</PDBx:U23>
         <PDBx:U33>0.2844</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3519">
         <PDBx:U11>0.2069</PDBx:U11>
         <PDBx:U12>-0.0633</PDBx:U12>
         <PDBx:U13>0.0113</PDBx:U13>
         <PDBx:U22>0.4997</PDBx:U22>
         <PDBx:U23>-0.0631</PDBx:U23>
         <PDBx:U33>0.2625</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3520">
         <PDBx:U11>0.2857</PDBx:U11>
         <PDBx:U12>-0.0840</PDBx:U12>
         <PDBx:U13>0.0203</PDBx:U13>
         <PDBx:U22>0.5819</PDBx:U22>
         <PDBx:U23>-0.0834</PDBx:U23>
         <PDBx:U33>0.3219</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3521">
         <PDBx:U11>0.2582</PDBx:U11>
         <PDBx:U12>-0.0924</PDBx:U12>
         <PDBx:U13>0.0187</PDBx:U13>
         <PDBx:U22>0.5936</PDBx:U22>
         <PDBx:U23>-0.0906</PDBx:U23>
         <PDBx:U33>0.2967</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLY</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>521</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLY</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>221</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3522">
         <PDBx:U11>0.2938</PDBx:U11>
         <PDBx:U12>-0.0927</PDBx:U12>
         <PDBx:U13>0.0305</PDBx:U13>
         <PDBx:U22>0.5492</PDBx:U22>
         <PDBx:U23>-0.0930</PDBx:U23>
         <PDBx:U33>0.3117</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3523">
         <PDBx:U11>0.3189</PDBx:U11>
         <PDBx:U12>-0.1127</PDBx:U12>
         <PDBx:U13>0.0436</PDBx:U13>
         <PDBx:U22>0.5674</PDBx:U22>
         <PDBx:U23>-0.1129</PDBx:U23>
         <PDBx:U33>0.3186</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3524">
         <PDBx:U11>0.3347</PDBx:U11>
         <PDBx:U12>-0.1260</PDBx:U12>
         <PDBx:U13>0.0493</PDBx:U13>
         <PDBx:U22>0.6083</PDBx:U22>
         <PDBx:U23>-0.1268</PDBx:U23>
         <PDBx:U33>0.3427</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3525">
         <PDBx:U11>0.4034</PDBx:U11>
         <PDBx:U12>-0.1423</PDBx:U12>
         <PDBx:U13>0.0559</PDBx:U13>
         <PDBx:U22>0.7024</PDBx:U22>
         <PDBx:U23>-0.1406</PDBx:U23>
         <PDBx:U33>0.4052</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3526">
         <PDBx:U11>0.4194</PDBx:U11>
         <PDBx:U12>-0.1132</PDBx:U12>
         <PDBx:U13>0.0512</PDBx:U13>
         <PDBx:U22>0.6090</PDBx:U22>
         <PDBx:U23>-0.1103</PDBx:U23>
         <PDBx:U33>0.4126</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3527">
         <PDBx:U11>0.4542</PDBx:U11>
         <PDBx:U12>-0.1272</PDBx:U12>
         <PDBx:U13>0.0639</PDBx:U13>
         <PDBx:U22>0.6247</PDBx:U22>
         <PDBx:U23>-0.1189</PDBx:U23>
         <PDBx:U33>0.4375</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3528">
         <PDBx:U11>0.5475</PDBx:U11>
         <PDBx:U12>-0.1233</PDBx:U12>
         <PDBx:U13>0.0617</PDBx:U13>
         <PDBx:U22>0.7195</PDBx:U22>
         <PDBx:U23>-0.1126</PDBx:U23>
         <PDBx:U33>0.5290</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3529">
         <PDBx:U11>0.4615</PDBx:U11>
         <PDBx:U12>-0.1070</PDBx:U12>
         <PDBx:U13>0.0516</PDBx:U13>
         <PDBx:U22>0.5920</PDBx:U22>
         <PDBx:U23>-0.0990</PDBx:U23>
         <PDBx:U33>0.4435</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>522</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>222</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3530">
         <PDBx:U11>0.3333</PDBx:U11>
         <PDBx:U12>-0.1201</PDBx:U12>
         <PDBx:U13>0.0480</PDBx:U13>
         <PDBx:U22>0.6019</PDBx:U22>
         <PDBx:U23>-0.1229</PDBx:U23>
         <PDBx:U33>0.3579</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3531">
         <PDBx:U11>0.3225</PDBx:U11>
         <PDBx:U12>-0.1320</PDBx:U12>
         <PDBx:U13>0.0535</PDBx:U13>
         <PDBx:U22>0.6171</PDBx:U22>
         <PDBx:U23>-0.1350</PDBx:U23>
         <PDBx:U33>0.3601</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3532">
         <PDBx:U11>0.3836</PDBx:U11>
         <PDBx:U12>-0.1332</PDBx:U12>
         <PDBx:U13>0.0443</PDBx:U13>
         <PDBx:U22>0.7393</PDBx:U22>
         <PDBx:U23>-0.1361</PDBx:U23>
         <PDBx:U33>0.4381</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3533">
         <PDBx:U11>0.4337</PDBx:U11>
         <PDBx:U12>-0.1524</PDBx:U12>
         <PDBx:U13>0.0509</PDBx:U13>
         <PDBx:U22>0.8157</PDBx:U22>
         <PDBx:U23>-0.1527</PDBx:U23>
         <PDBx:U33>0.4866</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3534">
         <PDBx:U11>0.2766</PDBx:U11>
         <PDBx:U12>-0.1212</PDBx:U12>
         <PDBx:U13>0.0533</PDBx:U13>
         <PDBx:U22>0.5642</PDBx:U22>
         <PDBx:U23>-0.1272</PDBx:U23>
         <PDBx:U33>0.3347</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3535">
         <PDBx:U11>0.4034</PDBx:U11>
         <PDBx:U12>-0.1356</PDBx:U12>
         <PDBx:U13>0.0630</PDBx:U13>
         <PDBx:U22>0.7105</PDBx:U22>
         <PDBx:U23>-0.1414</PDBx:U23>
         <PDBx:U33>0.4729</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3536">
         <PDBx:U11>0.4169</PDBx:U11>
         <PDBx:U12>-0.1244</PDBx:U12>
         <PDBx:U13>0.0657</PDBx:U13>
         <PDBx:U22>0.7181</PDBx:U22>
         <PDBx:U23>-0.1341</PDBx:U23>
         <PDBx:U33>0.5059</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3537">
         <PDBx:U11>0.3279</PDBx:U11>
         <PDBx:U12>-0.1063</PDBx:U12>
         <PDBx:U13>0.0606</PDBx:U13>
         <PDBx:U22>0.6073</PDBx:U22>
         <PDBx:U23>-0.1186</PDBx:U23>
         <PDBx:U33>0.4196</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3538">
         <PDBx:U11>0.4269</PDBx:U11>
         <PDBx:U12>-0.1349</PDBx:U12>
         <PDBx:U13>0.0747</PDBx:U13>
         <PDBx:U22>0.7469</PDBx:U22>
         <PDBx:U23>-0.1448</PDBx:U23>
         <PDBx:U33>0.5283</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>523</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>223</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3539">
         <PDBx:U11>0.3993</PDBx:U11>
         <PDBx:U12>-0.1134</PDBx:U12>
         <PDBx:U13>0.0294</PDBx:U13>
         <PDBx:U22>0.7776</PDBx:U22>
         <PDBx:U23>-0.1180</PDBx:U23>
         <PDBx:U33>0.4695</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3540">
         <PDBx:U11>0.4139</PDBx:U11>
         <PDBx:U12>-0.1115</PDBx:U12>
         <PDBx:U13>0.0181</PDBx:U13>
         <PDBx:U22>0.8504</PDBx:U22>
         <PDBx:U23>-0.1153</PDBx:U23>
         <PDBx:U33>0.4995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3541">
         <PDBx:U11>0.4238</PDBx:U11>
         <PDBx:U12>-0.1273</PDBx:U12>
         <PDBx:U13>0.0204</PDBx:U13>
         <PDBx:U22>0.8730</PDBx:U22>
         <PDBx:U23>-0.1247</PDBx:U23>
         <PDBx:U33>0.4857</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3542">
         <PDBx:U11>0.3914</PDBx:U11>
         <PDBx:U12>-0.1406</PDBx:U12>
         <PDBx:U13>0.0190</PDBx:U13>
         <PDBx:U22>0.8860</PDBx:U22>
         <PDBx:U23>-0.1354</PDBx:U23>
         <PDBx:U33>0.4583</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:U11>0.3888</PDBx:U11>
         <PDBx:U12>-0.0853</PDBx:U12>
         <PDBx:U13>0.0029</PDBx:U13>
         <PDBx:U22>0.8384</PDBx:U22>
         <PDBx:U23>-0.0915</PDBx:U23>
         <PDBx:U33>0.4938</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3544">
         <PDBx:U11>0.4101</PDBx:U11>
         <PDBx:U12>-0.0698</PDBx:U12>
         <PDBx:U13>0.0009</PDBx:U13>
         <PDBx:U22>0.8690</PDBx:U22>
         <PDBx:U23>-0.0843</PDBx:U23>
         <PDBx:U33>0.5483</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3545">
         <PDBx:U11>0.4706</PDBx:U11>
         <PDBx:U12>-0.0585</PDBx:U12>
         <PDBx:U13>0.0062</PDBx:U13>
         <PDBx:U22>0.8884</PDBx:U22>
         <PDBx:U23>-0.0765</PDBx:U23>
         <PDBx:U33>0.6125</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3546">
         <PDBx:U11>0.4114</PDBx:U11>
         <PDBx:U12>-0.0634</PDBx:U12>
         <PDBx:U13>-0.0044</PDBx:U13>
         <PDBx:U22>0.9190</PDBx:U22>
         <PDBx:U23>-0.0847</PDBx:U23>
         <PDBx:U33>0.5824</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3547">
         <PDBx:U11>0.4532</PDBx:U11>
         <PDBx:U12>-0.0460</PDBx:U12>
         <PDBx:U13>0.0063</PDBx:U13>
         <PDBx:U22>0.8920</PDBx:U22>
         <PDBx:U23>-0.0731</PDBx:U23>
         <PDBx:U33>0.6278</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3548">
         <PDBx:U11>0.4350</PDBx:U11>
         <PDBx:U12>-0.0476</PDBx:U12>
         <PDBx:U13>-0.0003</PDBx:U13>
         <PDBx:U22>0.9286</PDBx:U22>
         <PDBx:U23>-0.0776</PDBx:U23>
         <PDBx:U33>0.6292</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>524</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>224</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3549">
         <PDBx:U11>0.3880</PDBx:U11>
         <PDBx:U12>-0.1266</PDBx:U12>
         <PDBx:U13>0.0250</PDBx:U13>
         <PDBx:U22>0.8005</PDBx:U22>
         <PDBx:U23>-0.1215</PDBx:U23>
         <PDBx:U33>0.4262</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.4137</PDBx:U11>
         <PDBx:U12>-0.1406</PDBx:U12>
         <PDBx:U13>0.0302</PDBx:U13>
         <PDBx:U22>0.8382</PDBx:U22>
         <PDBx:U23>-0.1296</PDBx:U23>
         <PDBx:U33>0.4324</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.4537</PDBx:U11>
         <PDBx:U12>-0.1682</PDBx:U12>
         <PDBx:U13>0.0464</PDBx:U13>
         <PDBx:U22>0.8835</PDBx:U22>
         <PDBx:U23>-0.1544</PDBx:U23>
         <PDBx:U33>0.4620</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.4453</PDBx:U11>
         <PDBx:U12>-0.1826</PDBx:U12>
         <PDBx:U13>0.0462</PDBx:U13>
         <PDBx:U22>0.9142</PDBx:U22>
         <PDBx:U23>-0.1631</PDBx:U23>
         <PDBx:U33>0.4516</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3553">
         <PDBx:U11>0.3370</PDBx:U11>
         <PDBx:U12>-0.1347</PDBx:U12>
         <PDBx:U13>0.0355</PDBx:U13>
         <PDBx:U22>0.7215</PDBx:U22>
         <PDBx:U23>-0.1227</PDBx:U23>
         <PDBx:U33>0.3376</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3554">
         <PDBx:U11>0.3481</PDBx:U11>
         <PDBx:U12>-0.1155</PDBx:U12>
         <PDBx:U13>0.0214</PDBx:U13>
         <PDBx:U22>0.7420</PDBx:U22>
         <PDBx:U23>-0.0999</PDBx:U23>
         <PDBx:U33>0.3526</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3555">
         <PDBx:U11>0.3868</PDBx:U11>
         <PDBx:U12>-0.1121</PDBx:U12>
         <PDBx:U13>0.0277</PDBx:U13>
         <PDBx:U22>0.7422</PDBx:U22>
         <PDBx:U23>-0.0952</PDBx:U23>
         <PDBx:U33>0.3774</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3556">
         <PDBx:U11>0.3374</PDBx:U11>
         <PDBx:U12>-0.1196</PDBx:U12>
         <PDBx:U13>0.0128</PDBx:U13>
         <PDBx:U22>0.7835</PDBx:U22>
         <PDBx:U23>-0.0965</PDBx:U23>
         <PDBx:U33>0.3444</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>525</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>225</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3557">
         <PDBx:U11>0.4621</PDBx:U11>
         <PDBx:U12>-0.1771</PDBx:U12>
         <PDBx:U13>0.0610</PDBx:U13>
         <PDBx:U22>0.8519</PDBx:U22>
         <PDBx:U23>-0.1655</PDBx:U23>
         <PDBx:U33>0.4629</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3558">
         <PDBx:U11>0.5333</PDBx:U11>
         <PDBx:U12>-0.2051</PDBx:U12>
         <PDBx:U13>0.0797</PDBx:U13>
         <PDBx:U22>0.9208</PDBx:U22>
         <PDBx:U23>-0.1879</PDBx:U23>
         <PDBx:U33>0.5227</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3559">
         <PDBx:U11>0.5496</PDBx:U11>
         <PDBx:U12>-0.2172</PDBx:U12>
         <PDBx:U13>0.0779</PDBx:U13>
         <PDBx:U22>0.9749</PDBx:U22>
         <PDBx:U23>-0.1993</PDBx:U23>
         <PDBx:U33>0.5549</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3560">
         <PDBx:U11>0.6161</PDBx:U11>
         <PDBx:U12>-0.2408</PDBx:U12>
         <PDBx:U13>0.0948</PDBx:U13>
         <PDBx:U22>1.0314</PDBx:U22>
         <PDBx:U23>-0.2175</PDBx:U23>
         <PDBx:U33>0.6120</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3561">
         <PDBx:U11>0.5375</PDBx:U11>
         <PDBx:U12>-0.2092</PDBx:U12>
         <PDBx:U13>0.0947</PDBx:U13>
         <PDBx:U22>0.8531</PDBx:U22>
         <PDBx:U23>-0.1880</PDBx:U23>
         <PDBx:U33>0.5150</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3562">
         <PDBx:U11>0.5570</PDBx:U11>
         <PDBx:U12>-0.1972</PDBx:U12>
         <PDBx:U13>0.0945</PDBx:U13>
         <PDBx:U22>0.8340</PDBx:U22>
         <PDBx:U23>-0.1804</PDBx:U23>
         <PDBx:U33>0.5369</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3563">
         <PDBx:U11>0.5994</PDBx:U11>
         <PDBx:U12>-0.2028</PDBx:U12>
         <PDBx:U13>0.0959</PDBx:U13>
         <PDBx:U22>0.8999</PDBx:U22>
         <PDBx:U23>-0.1901</PDBx:U23>
         <PDBx:U33>0.5864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3564">
         <PDBx:U11>0.5696</PDBx:U11>
         <PDBx:U12>-0.1826</PDBx:U12>
         <PDBx:U13>0.0943</PDBx:U13>
         <PDBx:U22>0.7907</PDBx:U22>
         <PDBx:U23>-0.1651</PDBx:U23>
         <PDBx:U33>0.5449</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3565">
         <PDBx:U11>0.6167</PDBx:U11>
         <PDBx:U12>-0.1946</PDBx:U12>
         <PDBx:U13>0.0974</PDBx:U13>
         <PDBx:U22>0.8828</PDBx:U22>
         <PDBx:U23>-0.1844</PDBx:U23>
         <PDBx:U33>0.6056</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3566">
         <PDBx:U11>0.5675</PDBx:U11>
         <PDBx:U12>-0.1737</PDBx:U12>
         <PDBx:U13>0.0947</PDBx:U13>
         <PDBx:U22>0.7562</PDBx:U22>
         <PDBx:U23>-0.1582</PDBx:U23>
         <PDBx:U33>0.5432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3567">
         <PDBx:U11>0.5757</PDBx:U11>
         <PDBx:U12>-0.1802</PDBx:U12>
         <PDBx:U13>0.0966</PDBx:U13>
         <PDBx:U22>0.7851</PDBx:U22>
         <PDBx:U23>-0.1678</PDBx:U23>
         <PDBx:U33>0.5578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3568">
         <PDBx:U11>0.5402</PDBx:U11>
         <PDBx:U12>-0.1736</PDBx:U12>
         <PDBx:U13>0.0984</PDBx:U13>
         <PDBx:U22>0.7185</PDBx:U22>
         <PDBx:U23>-0.1619</PDBx:U23>
         <PDBx:U33>0.5223</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OH</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>TYR</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>526</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OH</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>TYR</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>226</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3569">
         <PDBx:U11>0.5224</PDBx:U11>
         <PDBx:U12>-0.2012</PDBx:U12>
         <PDBx:U13>0.0589</PDBx:U13>
         <PDBx:U22>0.9918</PDBx:U22>
         <PDBx:U23>-0.1875</PDBx:U23>
         <PDBx:U33>0.5540</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3570">
         <PDBx:U11>0.5381</PDBx:U11>
         <PDBx:U12>-0.2110</PDBx:U12>
         <PDBx:U13>0.0555</PDBx:U13>
         <PDBx:U22>1.0584</PDBx:U22>
         <PDBx:U23>-0.1969</PDBx:U23>
         <PDBx:U33>0.5929</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3571">
         <PDBx:U11>0.6132</PDBx:U11>
         <PDBx:U12>-0.2177</PDBx:U12>
         <PDBx:U13>0.0442</PDBx:U13>
         <PDBx:U22>1.1956</PDBx:U22>
         <PDBx:U23>-0.1992</PDBx:U23>
         <PDBx:U33>0.6744</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3572">
         <PDBx:U11>0.6990</PDBx:U11>
         <PDBx:U12>-0.2366</PDBx:U12>
         <PDBx:U13>0.0450</PDBx:U13>
         <PDBx:U22>1.3284</PDBx:U22>
         <PDBx:U23>-0.2143</PDBx:U23>
         <PDBx:U33>0.7710</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3573">
         <PDBx:U11>0.4683</PDBx:U11>
         <PDBx:U12>-0.1873</PDBx:U12>
         <PDBx:U13>0.0431</PDBx:U13>
         <PDBx:U22>1.0023</PDBx:U22>
         <PDBx:U23>-0.1812</PDBx:U23>
         <PDBx:U33>0.5550</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3574">
         <PDBx:U11>0.4339</PDBx:U11>
         <PDBx:U12>-0.1637</PDBx:U12>
         <PDBx:U13>0.0236</PDBx:U13>
         <PDBx:U22>0.9984</PDBx:U22>
         <PDBx:U23>-0.1609</PDBx:U23>
         <PDBx:U33>0.5368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>527</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>227</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3575">
         <PDBx:U11>0.8947</PDBx:U11>
         <PDBx:U12>-0.4226</PDBx:U12>
         <PDBx:U13>0.0819</PDBx:U13>
         <PDBx:U22>1.3432</PDBx:U22>
         <PDBx:U23>-0.2498</PDBx:U23>
         <PDBx:U33>1.0188</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3576">
         <PDBx:U11>0.8710</PDBx:U11>
         <PDBx:U12>-0.4170</PDBx:U12>
         <PDBx:U13>0.0562</PDBx:U13>
         <PDBx:U22>1.3724</PDBx:U22>
         <PDBx:U23>-0.2401</PDBx:U23>
         <PDBx:U33>1.0307</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3577">
         <PDBx:U11>0.8760</PDBx:U11>
         <PDBx:U12>-0.4108</PDBx:U12>
         <PDBx:U13>0.0386</PDBx:U13>
         <PDBx:U22>1.3531</PDBx:U22>
         <PDBx:U23>-0.2354</PDBx:U23>
         <PDBx:U33>0.9921</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3578">
         <PDBx:U11>0.8111</PDBx:U11>
         <PDBx:U12>-0.3974</PDBx:U12>
         <PDBx:U13>0.0189</PDBx:U13>
         <PDBx:U22>1.3029</PDBx:U22>
         <PDBx:U23>-0.2244</PDBx:U23>
         <PDBx:U33>0.9305</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3579">
         <PDBx:U11>0.8382</PDBx:U11>
         <PDBx:U12>-0.4017</PDBx:U12>
         <PDBx:U13>0.0480</PDBx:U13>
         <PDBx:U22>1.3745</PDBx:U22>
         <PDBx:U23>-0.2284</PDBx:U23>
         <PDBx:U33>1.0375</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3580">
         <PDBx:U11>0.8289</PDBx:U11>
         <PDBx:U12>-0.3893</PDBx:U12>
         <PDBx:U13>0.0550</PDBx:U13>
         <PDBx:U22>1.3204</PDBx:U22>
         <PDBx:U23>-0.2267</PDBx:U23>
         <PDBx:U33>0.9894</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3581">
         <PDBx:U11>0.7592</PDBx:U11>
         <PDBx:U12>-0.3713</PDBx:U12>
         <PDBx:U13>0.0491</PDBx:U13>
         <PDBx:U22>1.2916</PDBx:U22>
         <PDBx:U23>-0.2135</PDBx:U23>
         <PDBx:U33>0.9678</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3582">
         <PDBx:U11>0.5173</PDBx:U11>
         <PDBx:U12>-0.3571</PDBx:U12>
         <PDBx:U13>0.0118</PDBx:U13>
         <PDBx:U22>1.0765</PDBx:U22>
         <PDBx:U23>-0.1986</PDBx:U23>
         <PDBx:U33>0.7241</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>528</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>228</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3583">
         <PDBx:U11>0.9370</PDBx:U11>
         <PDBx:U12>-0.4196</PDBx:U12>
         <PDBx:U13>0.0472</PDBx:U13>
         <PDBx:U22>1.3757</PDBx:U22>
         <PDBx:U23>-0.2426</PDBx:U23>
         <PDBx:U33>1.0148</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3584">
         <PDBx:U11>0.9864</PDBx:U11>
         <PDBx:U12>-0.4134</PDBx:U12>
         <PDBx:U13>0.0354</PDBx:U13>
         <PDBx:U22>1.3997</PDBx:U22>
         <PDBx:U23>-0.2376</PDBx:U23>
         <PDBx:U33>1.0291</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3585">
         <PDBx:U11>1.0270</PDBx:U11>
         <PDBx:U12>-0.4177</PDBx:U12>
         <PDBx:U13>0.0154</PDBx:U13>
         <PDBx:U22>1.4850</PDBx:U22>
         <PDBx:U23>-0.2345</PDBx:U23>
         <PDBx:U33>1.0938</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3586">
         <PDBx:U11>1.0210</PDBx:U11>
         <PDBx:U12>-0.4083</PDBx:U12>
         <PDBx:U13>-0.0017</PDBx:U13>
         <PDBx:U22>1.5127</PDBx:U22>
         <PDBx:U23>-0.2249</PDBx:U23>
         <PDBx:U33>1.1125</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3587">
         <PDBx:U11>1.0243</PDBx:U11>
         <PDBx:U12>-0.4221</PDBx:U12>
         <PDBx:U13>0.0506</PDBx:U13>
         <PDBx:U22>1.3915</PDBx:U22>
         <PDBx:U23>-0.2443</PDBx:U23>
         <PDBx:U33>1.0300</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3588">
         <PDBx:U11>1.0169</PDBx:U11>
         <PDBx:U12>-0.4129</PDBx:U12>
         <PDBx:U13>0.0639</PDBx:U13>
         <PDBx:U22>1.3281</PDBx:U22>
         <PDBx:U23>-0.2402</PDBx:U23>
         <PDBx:U33>0.9865</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3589">
         <PDBx:U11>1.0396</PDBx:U11>
         <PDBx:U12>-0.4181</PDBx:U12>
         <PDBx:U13>0.0739</PDBx:U13>
         <PDBx:U22>1.3074</PDBx:U22>
         <PDBx:U23>-0.2416</PDBx:U23>
         <PDBx:U33>0.9763</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3590">
         <PDBx:U11>1.0758</PDBx:U11>
         <PDBx:U12>-0.4364</PDBx:U12>
         <PDBx:U13>0.0931</PDBx:U13>
         <PDBx:U22>1.3406</PDBx:U22>
         <PDBx:U23>-0.2537</PDBx:U23>
         <PDBx:U33>1.0134</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3591">
         <PDBx:U11>1.1111</PDBx:U11>
         <PDBx:U12>-0.4399</PDBx:U12>
         <PDBx:U13>0.1025</PDBx:U13>
         <PDBx:U22>1.3313</PDBx:U22>
         <PDBx:U23>-0.2527</PDBx:U23>
         <PDBx:U33>1.0158</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>529</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>229</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3592">
         <PDBx:U11>0.9325</PDBx:U11>
         <PDBx:U12>-0.3785</PDBx:U12>
         <PDBx:U13>-0.0534</PDBx:U13>
         <PDBx:U22>1.6127</PDBx:U22>
         <PDBx:U23>-0.1806</PDBx:U23>
         <PDBx:U33>1.2096</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3593">
         <PDBx:U11>0.9539</PDBx:U11>
         <PDBx:U12>-0.3860</PDBx:U12>
         <PDBx:U13>-0.0527</PDBx:U13>
         <PDBx:U22>1.5882</PDBx:U22>
         <PDBx:U23>-0.1903</PDBx:U23>
         <PDBx:U33>1.1701</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3594">
         <PDBx:U11>0.9860</PDBx:U11>
         <PDBx:U12>-0.3763</PDBx:U12>
         <PDBx:U13>-0.0743</PDBx:U13>
         <PDBx:U22>1.6143</PDBx:U22>
         <PDBx:U23>-0.1808</PDBx:U23>
         <PDBx:U33>1.1781</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3595">
         <PDBx:U11>0.9789</PDBx:U11>
         <PDBx:U12>-0.3691</PDBx:U12>
         <PDBx:U13>-0.0936</PDBx:U13>
         <PDBx:U22>1.6469</PDBx:U22>
         <PDBx:U23>-0.1672</PDBx:U23>
         <PDBx:U33>1.2040</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3596">
         <PDBx:U11>0.9475</PDBx:U11>
         <PDBx:U12>-0.4079</PDBx:U12>
         <PDBx:U13>-0.0479</PDBx:U13>
         <PDBx:U22>1.5944</PDBx:U22>
         <PDBx:U23>-0.2002</PDBx:U23>
         <PDBx:U33>1.1713</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3597">
         <PDBx:U11>0.9303</PDBx:U11>
         <PDBx:U12>-0.4138</PDBx:U12>
         <PDBx:U13>-0.0690</PDBx:U13>
         <PDBx:U22>1.6369</PDBx:U22>
         <PDBx:U23>-0.1897</PDBx:U23>
         <PDBx:U33>1.2031</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3598">
         <PDBx:U11>0.9499</PDBx:U11>
         <PDBx:U12>-0.4143</PDBx:U12>
         <PDBx:U13>-0.0438</PDBx:U13>
         <PDBx:U22>1.5486</PDBx:U22>
         <PDBx:U23>-0.2094</PDBx:U23>
         <PDBx:U33>1.1147</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>533</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>233</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3599">
         <PDBx:U11>1.0302</PDBx:U11>
         <PDBx:U12>-0.3759</PDBx:U12>
         <PDBx:U13>-0.0694</PDBx:U13>
         <PDBx:U22>1.6076</PDBx:U22>
         <PDBx:U23>-0.1869</PDBx:U23>
         <PDBx:U33>1.1677</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3600">
         <PDBx:U11>1.0636</PDBx:U11>
         <PDBx:U12>-0.3671</PDBx:U12>
         <PDBx:U13>-0.0839</PDBx:U13>
         <PDBx:U22>1.6252</PDBx:U22>
         <PDBx:U23>-0.1799</PDBx:U23>
         <PDBx:U33>1.1742</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3601">
         <PDBx:U11>1.1073</PDBx:U11>
         <PDBx:U12>-0.3717</PDBx:U12>
         <PDBx:U13>-0.0712</PDBx:U13>
         <PDBx:U22>1.6163</PDBx:U22>
         <PDBx:U23>-0.1893</PDBx:U23>
         <PDBx:U33>1.1703</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3602">
         <PDBx:U11>1.1294</PDBx:U11>
         <PDBx:U12>-0.3762</PDBx:U12>
         <PDBx:U13>-0.0529</PDBx:U13>
         <PDBx:U22>1.6103</PDBx:U22>
         <PDBx:U23>-0.1979</PDBx:U23>
         <PDBx:U33>1.1782</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3603">
         <PDBx:U11>1.0479</PDBx:U11>
         <PDBx:U12>-0.3442</PDBx:U12>
         <PDBx:U13>-0.0899</PDBx:U13>
         <PDBx:U22>1.5971</PDBx:U22>
         <PDBx:U23>-0.1691</PDBx:U23>
         <PDBx:U33>1.1536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3604">
         <PDBx:U11>1.0195</PDBx:U11>
         <PDBx:U12>-0.3355</PDBx:U12>
         <PDBx:U13>-0.0715</PDBx:U13>
         <PDBx:U22>1.5152</PDBx:U22>
         <PDBx:U23>-0.1742</PDBx:U23>
         <PDBx:U33>1.0911</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3605">
         <PDBx:U11>1.0557</PDBx:U11>
         <PDBx:U12>-0.3354</PDBx:U12>
         <PDBx:U13>-0.1067</PDBx:U13>
         <PDBx:U22>1.5982</PDBx:U22>
         <PDBx:U23>-0.1604</PDBx:U23>
         <PDBx:U33>1.1443</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>VAL</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>534</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>VAL</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>234</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3606">
         <PDBx:U11>1.1275</PDBx:U11>
         <PDBx:U12>-0.3719</PDBx:U12>
         <PDBx:U13>-0.0795</PDBx:U13>
         <PDBx:U22>1.6241</PDBx:U22>
         <PDBx:U23>-0.1874</PDBx:U23>
         <PDBx:U33>1.1678</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3607">
         <PDBx:U11>1.1270</PDBx:U11>
         <PDBx:U12>-0.3785</PDBx:U12>
         <PDBx:U13>-0.0626</PDBx:U13>
         <PDBx:U22>1.5812</PDBx:U22>
         <PDBx:U23>-0.1964</PDBx:U23>
         <PDBx:U33>1.1250</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3608">
         <PDBx:U11>1.0583</PDBx:U11>
         <PDBx:U12>-0.3621</PDBx:U12>
         <PDBx:U13>-0.0501</PDBx:U13>
         <PDBx:U22>1.4666</PDBx:U22>
         <PDBx:U23>-0.1942</PDBx:U23>
         <PDBx:U33>1.0364</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3609">
         <PDBx:U11>1.0375</PDBx:U11>
         <PDBx:U12>-0.3444</PDBx:U12>
         <PDBx:U13>-0.0568</PDBx:U13>
         <PDBx:U22>1.4391</PDBx:U22>
         <PDBx:U23>-0.1850</PDBx:U23>
         <PDBx:U33>1.0152</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3610">
         <PDBx:U11>1.1602</PDBx:U11>
         <PDBx:U12>-0.3829</PDBx:U12>
         <PDBx:U13>-0.0707</PDBx:U13>
         <PDBx:U22>1.6188</PDBx:U22>
         <PDBx:U23>-0.1943</PDBx:U23>
         <PDBx:U33>1.1378</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3611">
         <PDBx:U11>1.1573</PDBx:U11>
         <PDBx:U12>-0.3759</PDBx:U12>
         <PDBx:U13>-0.0927</PDBx:U13>
         <PDBx:U22>1.6568</PDBx:U22>
         <PDBx:U23>-0.1828</PDBx:U23>
         <PDBx:U33>1.1621</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3612">
         <PDBx:U11>1.1511</PDBx:U11>
         <PDBx:U12>-0.3766</PDBx:U12>
         <PDBx:U13>-0.0983</PDBx:U13>
         <PDBx:U22>1.6829</PDBx:U22>
         <PDBx:U23>-0.1809</PDBx:U23>
         <PDBx:U33>1.1995</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>PRO</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>535</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>PRO</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>235</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3613">
         <PDBx:U11>1.0277</PDBx:U11>
         <PDBx:U12>-0.3687</PDBx:U12>
         <PDBx:U13>-0.0324</PDBx:U13>
         <PDBx:U22>1.4051</PDBx:U22>
         <PDBx:U23>-0.2019</PDBx:U23>
         <PDBx:U33>0.9897</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3614">
         <PDBx:U11>1.0128</PDBx:U11>
         <PDBx:U12>-0.3561</PDBx:U12>
         <PDBx:U13>-0.0206</PDBx:U13>
         <PDBx:U22>1.3463</PDBx:U22>
         <PDBx:U23>-0.1987</PDBx:U23>
         <PDBx:U33>0.9561</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3615">
         <PDBx:U11>0.9900</PDBx:U11>
         <PDBx:U12>-0.3583</PDBx:U12>
         <PDBx:U13>-0.0100</PDBx:U13>
         <PDBx:U22>1.2849</PDBx:U22>
         <PDBx:U23>-0.2000</PDBx:U23>
         <PDBx:U33>0.9011</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3616">
         <PDBx:U11>1.0291</PDBx:U11>
         <PDBx:U12>-0.3659</PDBx:U12>
         <PDBx:U13>0.0044</PDBx:U13>
         <PDBx:U22>1.2974</PDBx:U22>
         <PDBx:U23>-0.2049</PDBx:U23>
         <PDBx:U33>0.9267</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3617">
         <PDBx:U11>1.0198</PDBx:U11>
         <PDBx:U12>-0.3613</PDBx:U12>
         <PDBx:U13>-0.0082</PDBx:U13>
         <PDBx:U22>1.3442</PDBx:U22>
         <PDBx:U23>-0.2038</PDBx:U23>
         <PDBx:U33>0.9710</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3618">
         <PDBx:U11>1.0181</PDBx:U11>
         <PDBx:U12>-0.3565</PDBx:U12>
         <PDBx:U13>-0.0083</PDBx:U13>
         <PDBx:U22>1.3631</PDBx:U22>
         <PDBx:U23>-0.2020</PDBx:U23>
         <PDBx:U33>0.9926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3619">
         <PDBx:U11>1.0407</PDBx:U11>
         <PDBx:U12>-0.3664</PDBx:U12>
         <PDBx:U13>-0.0193</PDBx:U13>
         <PDBx:U22>1.4463</PDBx:U22>
         <PDBx:U23>-0.2042</PDBx:U23>
         <PDBx:U33>1.0536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3620">
         <PDBx:U11>1.0183</PDBx:U11>
         <PDBx:U12>-0.3653</PDBx:U12>
         <PDBx:U13>0.0118</PDBx:U13>
         <PDBx:U22>1.3409</PDBx:U22>
         <PDBx:U23>-0.2090</PDBx:U23>
         <PDBx:U33>0.9843</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>536</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>236</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3621">
         <PDBx:U11>0.8966</PDBx:U11>
         <PDBx:U12>-0.3521</PDBx:U12>
         <PDBx:U13>-0.0170</PDBx:U13>
         <PDBx:U22>1.1886</PDBx:U22>
         <PDBx:U23>-0.1952</PDBx:U23>
         <PDBx:U33>0.7975</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3622">
         <PDBx:U11>0.8344</PDBx:U11>
         <PDBx:U12>-0.3534</PDBx:U12>
         <PDBx:U13>-0.0081</PDBx:U13>
         <PDBx:U22>1.0919</PDBx:U22>
         <PDBx:U23>-0.1955</PDBx:U23>
         <PDBx:U33>0.7106</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3623">
         <PDBx:U11>0.8118</PDBx:U11>
         <PDBx:U12>-0.3602</PDBx:U12>
         <PDBx:U13>0.0084</PDBx:U13>
         <PDBx:U22>1.0346</PDBx:U22>
         <PDBx:U23>-0.1997</PDBx:U23>
         <PDBx:U33>0.6738</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3624">
         <PDBx:U11>0.8948</PDBx:U11>
         <PDBx:U12>-0.3524</PDBx:U12>
         <PDBx:U13>0.0136</PDBx:U13>
         <PDBx:U22>1.0974</PDBx:U22>
         <PDBx:U23>-0.1953</PDBx:U23>
         <PDBx:U33>0.7555</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3625">
         <PDBx:U11>0.7916</PDBx:U11>
         <PDBx:U12>-0.3338</PDBx:U12>
         <PDBx:U13>-0.0134</PDBx:U13>
         <PDBx:U22>1.0291</PDBx:U22>
         <PDBx:U23>-0.1846</PDBx:U23>
         <PDBx:U33>0.6610</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3626">
         <PDBx:U11>0.7736</PDBx:U11>
         <PDBx:U12>-0.3203</PDBx:U12>
         <PDBx:U13>-0.0102</PDBx:U13>
         <PDBx:U22>0.9894</PDBx:U22>
         <PDBx:U23>-0.1777</PDBx:U23>
         <PDBx:U33>0.6434</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>SER</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>537</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>SER</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>237</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3627">
         <PDBx:U11>0.7594</PDBx:U11>
         <PDBx:U12>-0.3754</PDBx:U12>
         <PDBx:U13>0.0169</PDBx:U13>
         <PDBx:U22>0.9744</PDBx:U22>
         <PDBx:U23>-0.2079</PDBx:U23>
         <PDBx:U33>0.6092</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3628">
         <PDBx:U11>0.7157</PDBx:U11>
         <PDBx:U12>-0.3837</PDBx:U12>
         <PDBx:U13>0.0321</PDBx:U13>
         <PDBx:U22>0.8993</PDBx:U22>
         <PDBx:U23>-0.2122</PDBx:U23>
         <PDBx:U33>0.5522</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3629">
         <PDBx:U11>0.6775</PDBx:U11>
         <PDBx:U12>-0.3693</PDBx:U12>
         <PDBx:U13>0.0364</PDBx:U13>
         <PDBx:U22>0.8226</PDBx:U22>
         <PDBx:U23>-0.2021</PDBx:U23>
         <PDBx:U33>0.5050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3630">
         <PDBx:U11>0.6652</PDBx:U11>
         <PDBx:U12>-0.3741</PDBx:U12>
         <PDBx:U13>0.0460</PDBx:U13>
         <PDBx:U22>0.7924</PDBx:U22>
         <PDBx:U23>-0.2032</PDBx:U23>
         <PDBx:U33>0.4870</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3631">
         <PDBx:U11>0.7326</PDBx:U11>
         <PDBx:U12>-0.3962</PDBx:U12>
         <PDBx:U13>0.0400</PDBx:U13>
         <PDBx:U22>0.9031</PDBx:U22>
         <PDBx:U23>-0.2193</PDBx:U23>
         <PDBx:U33>0.5545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3632">
         <PDBx:U11>0.8252</PDBx:U11>
         <PDBx:U12>-0.4163</PDBx:U12>
         <PDBx:U13>0.0398</PDBx:U13>
         <PDBx:U22>1.0293</PDBx:U22>
         <PDBx:U23>-0.2310</PDBx:U23>
         <PDBx:U33>0.6509</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3633">
         <PDBx:U11>0.8344</PDBx:U11>
         <PDBx:U12>-0.4221</PDBx:U12>
         <PDBx:U13>0.0349</PDBx:U13>
         <PDBx:U22>1.0691</PDBx:U22>
         <PDBx:U23>-0.2341</PDBx:U23>
         <PDBx:U33>0.6750</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3634">
         <PDBx:U11>0.8489</PDBx:U11>
         <PDBx:U12>-0.4274</PDBx:U12>
         <PDBx:U13>0.0447</PDBx:U13>
         <PDBx:U22>1.0487</PDBx:U22>
         <PDBx:U23>-0.2371</PDBx:U23>
         <PDBx:U33>0.6629</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>538</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>238</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3635">
         <PDBx:U11>0.6361</PDBx:U11>
         <PDBx:U12>-0.3527</PDBx:U12>
         <PDBx:U13>0.0292</PDBx:U13>
         <PDBx:U22>0.7682</PDBx:U22>
         <PDBx:U23>-0.1919</PDBx:U23>
         <PDBx:U33>0.4608</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3636">
         <PDBx:U11>0.6219</PDBx:U11>
         <PDBx:U12>-0.3394</PDBx:U12>
         <PDBx:U13>0.0313</PDBx:U13>
         <PDBx:U22>0.7185</PDBx:U22>
         <PDBx:U23>-0.1808</PDBx:U23>
         <PDBx:U33>0.4371</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3637">
         <PDBx:U11>0.6078</PDBx:U11>
         <PDBx:U12>-0.3347</PDBx:U12>
         <PDBx:U13>0.0310</PDBx:U13>
         <PDBx:U22>0.7110</PDBx:U22>
         <PDBx:U23>-0.1774</PDBx:U23>
         <PDBx:U33>0.4302</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3638">
         <PDBx:U11>0.6131</PDBx:U11>
         <PDBx:U12>-0.3360</PDBx:U12>
         <PDBx:U13>0.0392</PDBx:U13>
         <PDBx:U22>0.6907</PDBx:U22>
         <PDBx:U23>-0.1740</PDBx:U23>
         <PDBx:U33>0.4248</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3639">
         <PDBx:U11>0.6029</PDBx:U11>
         <PDBx:U12>-0.3230</PDBx:U12>
         <PDBx:U13>0.0228</PDBx:U13>
         <PDBx:U22>0.6878</PDBx:U22>
         <PDBx:U23>-0.1711</PDBx:U23>
         <PDBx:U33>0.4155</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3640">
         <PDBx:U11>0.6427</PDBx:U11>
         <PDBx:U12>-0.3090</PDBx:U12>
         <PDBx:U13>0.0230</PDBx:U13>
         <PDBx:U22>0.6922</PDBx:U22>
         <PDBx:U23>-0.1582</PDBx:U23>
         <PDBx:U33>0.4452</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3641">
         <PDBx:U11>0.6307</PDBx:U11>
         <PDBx:U12>-0.3166</PDBx:U12>
         <PDBx:U13>0.0331</PDBx:U13>
         <PDBx:U22>0.6460</PDBx:U22>
         <PDBx:U23>-0.1578</PDBx:U23>
         <PDBx:U33>0.4178</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3642">
         <PDBx:U11>0.5718</PDBx:U11>
         <PDBx:U12>-0.2940</PDBx:U12>
         <PDBx:U13>0.0148</PDBx:U13>
         <PDBx:U22>0.6108</PDBx:U22>
         <PDBx:U23>-0.1500</PDBx:U23>
         <PDBx:U33>0.3729</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>539</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>239</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3643">
         <PDBx:U11>0.6323</PDBx:U11>
         <PDBx:U12>-0.3301</PDBx:U12>
         <PDBx:U13>0.0217</PDBx:U13>
         <PDBx:U22>0.7698</PDBx:U22>
         <PDBx:U23>-0.1784</PDBx:U23>
         <PDBx:U33>0.4725</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3644">
         <PDBx:U11>0.6604</PDBx:U11>
         <PDBx:U12>-0.3260</PDBx:U12>
         <PDBx:U13>0.0215</PDBx:U13>
         <PDBx:U22>0.8082</PDBx:U22>
         <PDBx:U23>-0.1769</PDBx:U23>
         <PDBx:U33>0.5113</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3645">
         <PDBx:U11>0.6811</PDBx:U11>
         <PDBx:U12>-0.3418</PDBx:U12>
         <PDBx:U13>0.0330</PDBx:U13>
         <PDBx:U22>0.8313</PDBx:U22>
         <PDBx:U23>-0.1861</PDBx:U23>
         <PDBx:U33>0.5336</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3646">
         <PDBx:U11>0.7061</PDBx:U11>
         <PDBx:U12>-0.3418</PDBx:U12>
         <PDBx:U13>0.0417</PDBx:U13>
         <PDBx:U22>0.8356</PDBx:U22>
         <PDBx:U23>-0.1835</PDBx:U23>
         <PDBx:U33>0.5508</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3647">
         <PDBx:U11>0.7054</PDBx:U11>
         <PDBx:U12>-0.3197</PDBx:U12>
         <PDBx:U13>0.0080</PDBx:U13>
         <PDBx:U22>0.8940</PDBx:U22>
         <PDBx:U23>-0.1774</PDBx:U23>
         <PDBx:U33>0.5791</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3648">
         <PDBx:U11>0.6764</PDBx:U11>
         <PDBx:U12>-0.3060</PDBx:U12>
         <PDBx:U13>0.0037</PDBx:U13>
         <PDBx:U22>0.8691</PDBx:U22>
         <PDBx:U23>-0.1710</PDBx:U23>
         <PDBx:U33>0.5606</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3649">
         <PDBx:U11>0.6508</PDBx:U11>
         <PDBx:U12>-0.2959</PDBx:U12>
         <PDBx:U13>0.0101</PDBx:U13>
         <PDBx:U22>0.8005</PDBx:U22>
         <PDBx:U23>-0.1612</PDBx:U23>
         <PDBx:U33>0.5140</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3650">
         <PDBx:U11>0.6581</PDBx:U11>
         <PDBx:U12>-0.2944</PDBx:U12>
         <PDBx:U13>-0.0123</PDBx:U13>
         <PDBx:U22>0.8803</PDBx:U22>
         <PDBx:U23>-0.1666</PDBx:U23>
         <PDBx:U33>0.5585</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>540</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>240</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.6772</PDBx:U11>
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         <PDBx:U13>0.0336</PDBx:U13>
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         <PDBx:U23>-0.1967</PDBx:U23>
         <PDBx:U33>0.5379</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
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         <PDBx:U11>0.7027</PDBx:U11>
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         <PDBx:U13>0.0447</PDBx:U13>
         <PDBx:U22>0.8807</PDBx:U22>
         <PDBx:U23>-0.2065</PDBx:U23>
         <PDBx:U33>0.5656</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.6870</PDBx:U11>
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         <PDBx:U13>0.0587</PDBx:U13>
         <PDBx:U22>0.8211</PDBx:U22>
         <PDBx:U23>-0.2041</PDBx:U23>
         <PDBx:U33>0.5254</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.6607</PDBx:U11>
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         <PDBx:U13>0.0684</PDBx:U13>
         <PDBx:U22>0.7854</PDBx:U22>
         <PDBx:U23>-0.2062</PDBx:U23>
         <PDBx:U33>0.4964</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
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         <PDBx:U11>0.7397</PDBx:U11>
         <PDBx:U12>-0.3889</PDBx:U12>
         <PDBx:U13>0.0435</PDBx:U13>
         <PDBx:U22>0.9453</PDBx:U22>
         <PDBx:U23>-0.2174</PDBx:U23>
         <PDBx:U33>0.6101</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3656">
         <PDBx:U11>0.7769</PDBx:U11>
         <PDBx:U12>-0.3926</PDBx:U12>
         <PDBx:U13>0.0313</PDBx:U13>
         <PDBx:U22>1.0323</PDBx:U22>
         <PDBx:U23>-0.2216</PDBx:U23>
         <PDBx:U33>0.6762</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3657">
         <PDBx:U11>0.8425</PDBx:U11>
         <PDBx:U12>-0.4113</PDBx:U12>
         <PDBx:U13>0.0310</PDBx:U13>
         <PDBx:U22>1.1214</PDBx:U22>
         <PDBx:U23>-0.2318</PDBx:U23>
         <PDBx:U33>0.7445</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3658">
         <PDBx:U11>0.7634</PDBx:U11>
         <PDBx:U12>-0.3933</PDBx:U12>
         <PDBx:U13>0.0346</PDBx:U13>
         <PDBx:U22>1.0307</PDBx:U22>
         <PDBx:U23>-0.2237</PDBx:U23>
         <PDBx:U33>0.6828</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>541</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>241</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3659">
         <PDBx:U11>0.6601</PDBx:U11>
         <PDBx:U12>-0.3743</PDBx:U12>
         <PDBx:U13>0.0596</PDBx:U13>
         <PDBx:U22>0.7674</PDBx:U22>
         <PDBx:U23>-0.1995</PDBx:U23>
         <PDBx:U33>0.4812</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3660">
         <PDBx:U11>0.7557</PDBx:U11>
         <PDBx:U12>-0.3774</PDBx:U12>
         <PDBx:U13>0.0700</PDBx:U13>
         <PDBx:U22>0.8211</PDBx:U22>
         <PDBx:U23>-0.1953</PDBx:U23>
         <PDBx:U33>0.5545</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3661">
         <PDBx:U11>0.6639</PDBx:U11>
         <PDBx:U12>-0.3660</PDBx:U12>
         <PDBx:U13>0.0705</PDBx:U13>
         <PDBx:U22>0.7031</PDBx:U22>
         <PDBx:U23>-0.1829</PDBx:U23>
         <PDBx:U33>0.4513</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3662">
         <PDBx:U11>0.6806</PDBx:U11>
         <PDBx:U12>-0.3718</PDBx:U12>
         <PDBx:U13>0.0799</PDBx:U13>
         <PDBx:U22>0.6927</PDBx:U22>
         <PDBx:U23>-0.1803</PDBx:U23>
         <PDBx:U33>0.4511</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3663">
         <PDBx:U11>0.7998</PDBx:U11>
         <PDBx:U12>-0.3767</PDBx:U12>
         <PDBx:U13>0.0693</PDBx:U13>
         <PDBx:U22>0.8441</PDBx:U22>
         <PDBx:U23>-0.1934</PDBx:U23>
         <PDBx:U33>0.5871</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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         <PDBx:U11>0.8626</PDBx:U11>
         <PDBx:U12>-0.3922</PDBx:U12>
         <PDBx:U13>0.0733</PDBx:U13>
         <PDBx:U22>0.9251</PDBx:U22>
         <PDBx:U23>-0.2067</PDBx:U23>
         <PDBx:U33>0.6543</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
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      <PDBx:atom_site_anisotrop id="3665">
         <PDBx:U11>0.8869</PDBx:U11>
         <PDBx:U12>-0.3923</PDBx:U12>
         <PDBx:U13>0.0749</PDBx:U13>
         <PDBx:U22>0.9268</PDBx:U22>
         <PDBx:U23>-0.2063</PDBx:U23>
         <PDBx:U33>0.6680</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3666">
         <PDBx:U11>0.8267</PDBx:U11>
         <PDBx:U12>-0.3788</PDBx:U12>
         <PDBx:U13>0.0708</PDBx:U13>
         <PDBx:U22>0.8394</PDBx:U22>
         <PDBx:U23>-0.1954</PDBx:U23>
         <PDBx:U33>0.6001</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3667">
         <PDBx:U11>0.9595</PDBx:U11>
         <PDBx:U12>-0.4065</PDBx:U12>
         <PDBx:U13>0.0806</PDBx:U13>
         <PDBx:U22>1.0088</PDBx:U22>
         <PDBx:U23>-0.2175</PDBx:U23>
         <PDBx:U33>0.7404</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>542</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>242</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3668">
         <PDBx:U11>0.6368</PDBx:U11>
         <PDBx:U12>-0.3508</PDBx:U12>
         <PDBx:U13>0.0605</PDBx:U13>
         <PDBx:U22>0.6836</PDBx:U22>
         <PDBx:U23>-0.1751</PDBx:U23>
         <PDBx:U33>0.4315</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3669">
         <PDBx:U11>0.6247</PDBx:U11>
         <PDBx:U12>-0.3406</PDBx:U12>
         <PDBx:U13>0.0611</PDBx:U13>
         <PDBx:U22>0.6488</PDBx:U22>
         <PDBx:U23>-0.1634</PDBx:U23>
         <PDBx:U33>0.4083</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3670">
         <PDBx:U11>0.7121</PDBx:U11>
         <PDBx:U12>-0.3473</PDBx:U12>
         <PDBx:U13>0.0695</PDBx:U13>
         <PDBx:U22>0.7465</PDBx:U22>
         <PDBx:U23>-0.1687</PDBx:U23>
         <PDBx:U33>0.5008</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3671">
         <PDBx:U11>0.7037</PDBx:U11>
         <PDBx:U12>-0.3504</PDBx:U12>
         <PDBx:U13>0.0786</PDBx:U13>
         <PDBx:U22>0.7101</PDBx:U22>
         <PDBx:U23>-0.1635</PDBx:U23>
         <PDBx:U33>0.4727</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3672">
         <PDBx:U11>0.6036</PDBx:U11>
         <PDBx:U12>-0.3229</PDBx:U12>
         <PDBx:U13>0.0488</PDBx:U13>
         <PDBx:U22>0.6344</PDBx:U22>
         <PDBx:U23>-0.1548</PDBx:U23>
         <PDBx:U33>0.3948</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3673">
         <PDBx:U11>0.6180</PDBx:U11>
         <PDBx:U12>-0.3154</PDBx:U12>
         <PDBx:U13>0.0419</PDBx:U13>
         <PDBx:U22>0.6340</PDBx:U22>
         <PDBx:U23>-0.1489</PDBx:U23>
         <PDBx:U33>0.4030</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3674">
         <PDBx:U11>0.8560</PDBx:U11>
         <PDBx:U12>-0.3144</PDBx:U12>
         <PDBx:U13>0.0462</PDBx:U13>
         <PDBx:U22>0.8202</PDBx:U22>
         <PDBx:U23>-0.1369</PDBx:U23>
         <PDBx:U33>0.6129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>SD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>SD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>S</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3675">
         <PDBx:U11>0.6766</PDBx:U11>
         <PDBx:U12>-0.2986</PDBx:U12>
         <PDBx:U13>0.0411</PDBx:U13>
         <PDBx:U22>0.6237</PDBx:U22>
         <PDBx:U23>-0.1207</PDBx:U23>
         <PDBx:U33>0.4242</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>MET</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>543</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>MET</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>243</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3676">
         <PDBx:U11>0.6191</PDBx:U11>
         <PDBx:U12>-0.3503</PDBx:U12>
         <PDBx:U13>0.0663</PDBx:U13>
         <PDBx:U22>0.6936</PDBx:U22>
         <PDBx:U23>-0.1791</PDBx:U23>
         <PDBx:U33>0.4338</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3677">
         <PDBx:U11>0.7172</PDBx:U11>
         <PDBx:U12>-0.3576</PDBx:U12>
         <PDBx:U13>0.0747</PDBx:U13>
         <PDBx:U22>0.8051</PDBx:U22>
         <PDBx:U23>-0.1867</PDBx:U23>
         <PDBx:U33>0.5430</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3678">
         <PDBx:U11>0.7281</PDBx:U11>
         <PDBx:U12>-0.3750</PDBx:U12>
         <PDBx:U13>0.0895</PDBx:U13>
         <PDBx:U22>0.8016</PDBx:U22>
         <PDBx:U23>-0.1941</PDBx:U23>
         <PDBx:U33>0.5414</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3679">
         <PDBx:U11>0.7159</PDBx:U11>
         <PDBx:U12>-0.3804</PDBx:U12>
         <PDBx:U13>0.1017</PDBx:U13>
         <PDBx:U22>0.7717</PDBx:U22>
         <PDBx:U23>-0.1945</PDBx:U23>
         <PDBx:U33>0.5177</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3680">
         <PDBx:U11>0.7571</PDBx:U11>
         <PDBx:U12>-0.3581</PDBx:U12>
         <PDBx:U13>0.0656</PDBx:U13>
         <PDBx:U22>0.8942</PDBx:U22>
         <PDBx:U23>-0.1957</PDBx:U23>
         <PDBx:U33>0.6184</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3681">
         <PDBx:U11>0.7684</PDBx:U11>
         <PDBx:U12>-0.3468</PDBx:U12>
         <PDBx:U13>0.0565</PDBx:U13>
         <PDBx:U22>0.9280</PDBx:U22>
         <PDBx:U23>-0.1920</PDBx:U23>
         <PDBx:U33>0.6442</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3682">
         <PDBx:U11>0.7534</PDBx:U11>
         <PDBx:U12>-0.3292</PDBx:U12>
         <PDBx:U13>0.0402</PDBx:U13>
         <PDBx:U22>0.9063</PDBx:U22>
         <PDBx:U23>-0.1812</PDBx:U23>
         <PDBx:U33>0.6258</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3683">
         <PDBx:U11>0.8121</PDBx:U11>
         <PDBx:U12>-0.3582</PDBx:U12>
         <PDBx:U13>0.0544</PDBx:U13>
         <PDBx:U22>1.0276</PDBx:U22>
         <PDBx:U23>-0.2041</PDBx:U23>
         <PDBx:U33>0.7214</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>544</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>244</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3684">
         <PDBx:U11>0.7291</PDBx:U11>
         <PDBx:U12>-0.3844</PDBx:U12>
         <PDBx:U13>0.0892</PDBx:U13>
         <PDBx:U22>0.8092</PDBx:U22>
         <PDBx:U23>-0.2005</PDBx:U23>
         <PDBx:U33>0.5429</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3685">
         <PDBx:U11>0.7651</PDBx:U11>
         <PDBx:U12>-0.4011</PDBx:U12>
         <PDBx:U13>0.1026</PDBx:U13>
         <PDBx:U22>0.8323</PDBx:U22>
         <PDBx:U23>-0.2083</PDBx:U23>
         <PDBx:U33>0.5671</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3686">
         <PDBx:U11>0.7630</PDBx:U11>
         <PDBx:U12>-0.4012</PDBx:U12>
         <PDBx:U13>0.1027</PDBx:U13>
         <PDBx:U22>0.8304</PDBx:U22>
         <PDBx:U23>-0.2083</PDBx:U23>
         <PDBx:U33>0.5653</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3687">
         <PDBx:U11>0.7647</PDBx:U11>
         <PDBx:U12>-0.4022</PDBx:U12>
         <PDBx:U13>0.1126</PDBx:U13>
         <PDBx:U22>0.7858</PDBx:U22>
         <PDBx:U23>-0.1991</PDBx:U23>
         <PDBx:U33>0.5344</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3688">
         <PDBx:U11>0.7422</PDBx:U11>
         <PDBx:U12>-0.4147</PDBx:U12>
         <PDBx:U13>0.1258</PDBx:U13>
         <PDBx:U22>0.7514</PDBx:U22>
         <PDBx:U23>-0.2044</PDBx:U23>
         <PDBx:U33>0.5010</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3689">
         <PDBx:U11>0.7887</PDBx:U11>
         <PDBx:U12>-0.4085</PDBx:U12>
         <PDBx:U13>0.1004</PDBx:U13>
         <PDBx:U22>0.8598</PDBx:U22>
         <PDBx:U23>-0.2133</PDBx:U23>
         <PDBx:U33>0.5893</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3690">
         <PDBx:U11>0.7925</PDBx:U11>
         <PDBx:U12>-0.4097</PDBx:U12>
         <PDBx:U13>0.1011</PDBx:U13>
         <PDBx:U22>0.8660</PDBx:U22>
         <PDBx:U23>-0.2145</PDBx:U23>
         <PDBx:U33>0.5946</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3691">
         <PDBx:U11>0.8457</PDBx:U11>
         <PDBx:U12>-0.4274</PDBx:U12>
         <PDBx:U13>0.1129</PDBx:U13>
         <PDBx:U22>0.9172</PDBx:U22>
         <PDBx:U23>-0.2251</PDBx:U23>
         <PDBx:U33>0.6432</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3692">
         <PDBx:U11>0.8183</PDBx:U11>
         <PDBx:U12>-0.4180</PDBx:U12>
         <PDBx:U13>0.0963</PDBx:U13>
         <PDBx:U22>0.9379</PDBx:U22>
         <PDBx:U23>-0.2270</PDBx:U23>
         <PDBx:U33>0.6479</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3693">
         <PDBx:U11>0.8749</PDBx:U11>
         <PDBx:U12>-0.4357</PDBx:U12>
         <PDBx:U13>0.1177</PDBx:U13>
         <PDBx:U22>0.9701</PDBx:U22>
         <PDBx:U23>-0.2345</PDBx:U23>
         <PDBx:U33>0.6889</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3694">
         <PDBx:U11>0.7794</PDBx:U11>
         <PDBx:U12>-0.4113</PDBx:U12>
         <PDBx:U13>0.0873</PDBx:U13>
         <PDBx:U22>0.9295</PDBx:U22>
         <PDBx:U23>-0.2273</PDBx:U23>
         <PDBx:U33>0.6325</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3695">
         <PDBx:U11>0.8815</PDBx:U11>
         <PDBx:U12>-0.4339</PDBx:U12>
         <PDBx:U13>0.1179</PDBx:U13>
         <PDBx:U22>0.9296</PDBx:U22>
         <PDBx:U23>-0.2252</PDBx:U23>
         <PDBx:U33>0.6616</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>A</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3696">
         <PDBx:U11>0.8957</PDBx:U11>
         <PDBx:U12>-0.4317</PDBx:U12>
         <PDBx:U13>0.1009</PDBx:U13>
         <PDBx:U22>1.0212</PDBx:U22>
         <PDBx:U23>-0.2360</PDBx:U23>
         <PDBx:U33>0.7239</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>545</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id>B</PDBx:pdbx_label_alt_id>
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>245</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3697">
         <PDBx:U11>0.7550</PDBx:U11>
         <PDBx:U12>-0.3896</PDBx:U12>
         <PDBx:U13>0.1057</PDBx:U13>
         <PDBx:U22>0.7502</PDBx:U22>
         <PDBx:U23>-0.1849</PDBx:U23>
         <PDBx:U33>0.5084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3698">
         <PDBx:U11>0.7747</PDBx:U11>
         <PDBx:U12>-0.3901</PDBx:U12>
         <PDBx:U13>0.1114</PDBx:U13>
         <PDBx:U22>0.7260</PDBx:U22>
         <PDBx:U23>-0.1733</PDBx:U23>
         <PDBx:U33>0.4952</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3699">
         <PDBx:U11>0.8001</PDBx:U11>
         <PDBx:U12>-0.3937</PDBx:U12>
         <PDBx:U13>0.1221</PDBx:U13>
         <PDBx:U22>0.7431</PDBx:U22>
         <PDBx:U23>-0.1728</PDBx:U23>
         <PDBx:U33>0.5099</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3700">
         <PDBx:U11>0.8135</PDBx:U11>
         <PDBx:U12>-0.4013</PDBx:U12>
         <PDBx:U13>0.1309</PDBx:U13>
         <PDBx:U22>0.7239</PDBx:U22>
         <PDBx:U23>-0.1677</PDBx:U23>
         <PDBx:U33>0.4934</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3701">
         <PDBx:U11>0.7101</PDBx:U11>
         <PDBx:U12>-0.3748</PDBx:U12>
         <PDBx:U13>0.0997</PDBx:U13>
         <PDBx:U22>0.6401</PDBx:U22>
         <PDBx:U23>-0.1578</PDBx:U23>
         <PDBx:U33>0.4196</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ALA</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>546</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ALA</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>246</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3702">
         <PDBx:U11>0.7796</PDBx:U11>
         <PDBx:U12>-0.3888</PDBx:U12>
         <PDBx:U13>0.1212</PDBx:U13>
         <PDBx:U22>0.7516</PDBx:U22>
         <PDBx:U23>-0.1785</PDBx:U23>
         <PDBx:U33>0.5132</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3703">
         <PDBx:U11>0.7637</PDBx:U11>
         <PDBx:U12>-0.3925</PDBx:U12>
         <PDBx:U13>0.1333</PDBx:U13>
         <PDBx:U22>0.7297</PDBx:U22>
         <PDBx:U23>-0.1806</PDBx:U23>
         <PDBx:U33>0.4911</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3704">
         <PDBx:U11>0.8261</PDBx:U11>
         <PDBx:U12>-0.4069</PDBx:U12>
         <PDBx:U13>0.1452</PDBx:U13>
         <PDBx:U22>0.8147</PDBx:U22>
         <PDBx:U23>-0.1980</PDBx:U23>
         <PDBx:U33>0.5722</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3705">
         <PDBx:U11>0.8492</PDBx:U11>
         <PDBx:U12>-0.4192</PDBx:U12>
         <PDBx:U13>0.1623</PDBx:U13>
         <PDBx:U22>0.8198</PDBx:U22>
         <PDBx:U23>-0.2026</PDBx:U23>
         <PDBx:U33>0.5761</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3706">
         <PDBx:U11>0.7338</PDBx:U11>
         <PDBx:U12>-0.3780</PDBx:U12>
         <PDBx:U13>0.1263</PDBx:U13>
         <PDBx:U22>0.7139</PDBx:U22>
         <PDBx:U23>-0.1764</PDBx:U23>
         <PDBx:U33>0.4767</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3707">
         <PDBx:U11>0.7815</PDBx:U11>
         <PDBx:U12>-0.3653</PDBx:U12>
         <PDBx:U13>0.1182</PDBx:U13>
         <PDBx:U22>0.7336</PDBx:U22>
         <PDBx:U23>-0.1586</PDBx:U23>
         <PDBx:U33>0.5013</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3708">
         <PDBx:U11>0.7813</PDBx:U11>
         <PDBx:U12>-0.3643</PDBx:U12>
         <PDBx:U13>0.1259</PDBx:U13>
         <PDBx:U22>0.7037</PDBx:U22>
         <PDBx:U23>-0.1490</PDBx:U23>
         <PDBx:U33>0.4727</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3709">
         <PDBx:U11>0.7471</PDBx:U11>
         <PDBx:U12>-0.3537</PDBx:U12>
         <PDBx:U13>0.1036</PDBx:U13>
         <PDBx:U22>0.6960</PDBx:U22>
         <PDBx:U23>-0.1487</PDBx:U23>
         <PDBx:U33>0.4673</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3710">
         <PDBx:U11>0.7482</PDBx:U11>
         <PDBx:U12>-0.3526</PDBx:U12>
         <PDBx:U13>0.1150</PDBx:U13>
         <PDBx:U22>0.6516</PDBx:U22>
         <PDBx:U23>-0.1330</PDBx:U23>
         <PDBx:U33>0.4247</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3711">
         <PDBx:U11>0.7268</PDBx:U11>
         <PDBx:U12>-0.3456</PDBx:U12>
         <PDBx:U13>0.1016</PDBx:U13>
         <PDBx:U22>0.6455</PDBx:U22>
         <PDBx:U23>-0.1330</PDBx:U23>
         <PDBx:U33>0.4219</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>547</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>247</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3712">
         <PDBx:U11>0.8355</PDBx:U11>
         <PDBx:U12>-0.4105</PDBx:U12>
         <PDBx:U13>0.1394</PDBx:U13>
         <PDBx:U22>0.8645</PDBx:U22>
         <PDBx:U23>-0.2094</PDBx:U23>
         <PDBx:U33>0.6132</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3713">
         <PDBx:U11>0.9161</PDBx:U11>
         <PDBx:U12>-0.4295</PDBx:U12>
         <PDBx:U13>0.1523</PDBx:U13>
         <PDBx:U22>0.9728</PDBx:U22>
         <PDBx:U23>-0.2281</PDBx:U23>
         <PDBx:U33>0.7115</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3714">
         <PDBx:U11>0.9475</PDBx:U11>
         <PDBx:U12>-0.4413</PDBx:U12>
         <PDBx:U13>0.1620</PDBx:U13>
         <PDBx:U22>0.9790</PDBx:U22>
         <PDBx:U23>-0.2303</PDBx:U23>
         <PDBx:U33>0.7226</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3715">
         <PDBx:U11>0.9298</PDBx:U11>
         <PDBx:U12>-0.4383</PDBx:U12>
         <PDBx:U13>0.1555</PDBx:U13>
         <PDBx:U22>0.9400</PDBx:U22>
         <PDBx:U23>-0.2221</PDBx:U23>
         <PDBx:U33>0.6879</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3716">
         <PDBx:U11>0.9084</PDBx:U11>
         <PDBx:U12>-0.4304</PDBx:U12>
         <PDBx:U13>0.1398</PDBx:U13>
         <PDBx:U22>1.0141</PDBx:U22>
         <PDBx:U23>-0.2366</PDBx:U23>
         <PDBx:U33>0.7403</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>548</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>248</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3717">
         <PDBx:U11>1.0124</PDBx:U11>
         <PDBx:U12>-0.4584</PDBx:U12>
         <PDBx:U13>0.1809</PDBx:U13>
         <PDBx:U22>1.0472</PDBx:U22>
         <PDBx:U23>-0.2440</PDBx:U23>
         <PDBx:U33>0.7870</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3718">
         <PDBx:U11>1.0264</PDBx:U11>
         <PDBx:U12>-0.4655</PDBx:U12>
         <PDBx:U13>0.1926</PDBx:U13>
         <PDBx:U22>1.0876</PDBx:U22>
         <PDBx:U23>-0.2571</PDBx:U23>
         <PDBx:U33>0.8230</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3719">
         <PDBx:U11>1.0244</PDBx:U11>
         <PDBx:U12>-0.4676</PDBx:U12>
         <PDBx:U13>0.2099</PDBx:U13>
         <PDBx:U22>1.0493</PDBx:U22>
         <PDBx:U23>-0.2549</PDBx:U23>
         <PDBx:U33>0.7910</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3720">
         <PDBx:U11>1.0078</PDBx:U11>
         <PDBx:U12>-0.4734</PDBx:U12>
         <PDBx:U13>0.2238</PDBx:U13>
         <PDBx:U22>1.0457</PDBx:U22>
         <PDBx:U23>-0.2664</PDBx:U23>
         <PDBx:U33>0.7895</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3721">
         <PDBx:U11>1.0722</PDBx:U11>
         <PDBx:U12>-0.4836</PDBx:U12>
         <PDBx:U13>0.2029</PDBx:U13>
         <PDBx:U22>1.1668</PDBx:U22>
         <PDBx:U23>-0.2763</PDBx:U23>
         <PDBx:U33>0.8973</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>549</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>B</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>249</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3722">
         <PDBx:U11>0.6880</PDBx:U11>
         <PDBx:U12>-0.0074</PDBx:U12>
         <PDBx:U13>0.3163</PDBx:U13>
         <PDBx:U22>0.9637</PDBx:U22>
         <PDBx:U23>0.0423</PDBx:U23>
         <PDBx:U33>1.1595</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>687</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3723">
         <PDBx:U11>0.6977</PDBx:U11>
         <PDBx:U12>-0.0090</PDBx:U12>
         <PDBx:U13>0.3019</PDBx:U13>
         <PDBx:U22>0.9435</PDBx:U22>
         <PDBx:U23>0.0550</PDBx:U23>
         <PDBx:U33>1.1575</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>687</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3724">
         <PDBx:U11>0.6931</PDBx:U11>
         <PDBx:U12>-0.0245</PDBx:U12>
         <PDBx:U13>0.2927</PDBx:U13>
         <PDBx:U22>0.9391</PDBx:U22>
         <PDBx:U23>0.0564</PDBx:U23>
         <PDBx:U33>1.1217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>687</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3725">
         <PDBx:U11>0.7201</PDBx:U11>
         <PDBx:U12>-0.0334</PDBx:U12>
         <PDBx:U13>0.2931</PDBx:U13>
         <PDBx:U22>0.9931</PDBx:U22>
         <PDBx:U23>0.0538</PDBx:U23>
         <PDBx:U33>1.1383</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>687</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3726">
         <PDBx:U11>0.6874</PDBx:U11>
         <PDBx:U12>-0.0034</PDBx:U12>
         <PDBx:U13>0.3042</PDBx:U13>
         <PDBx:U22>0.8995</PDBx:U22>
         <PDBx:U23>0.0543</PDBx:U23>
         <PDBx:U33>1.1536</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>687</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>2</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3727">
         <PDBx:U11>0.6357</PDBx:U11>
         <PDBx:U12>-0.0277</PDBx:U12>
         <PDBx:U13>0.2842</PDBx:U13>
         <PDBx:U22>0.8527</PDBx:U22>
         <PDBx:U23>0.0609</PDBx:U23>
         <PDBx:U33>1.0501</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3728">
         <PDBx:U11>0.6069</PDBx:U11>
         <PDBx:U12>-0.0409</PDBx:U12>
         <PDBx:U13>0.2740</PDBx:U13>
         <PDBx:U22>0.8217</PDBx:U22>
         <PDBx:U23>0.0633</PDBx:U23>
         <PDBx:U33>0.9932</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3729">
         <PDBx:U11>0.5885</PDBx:U11>
         <PDBx:U12>-0.0539</PDBx:U12>
         <PDBx:U13>0.2813</PDBx:U13>
         <PDBx:U22>0.8132</PDBx:U22>
         <PDBx:U23>0.0527</PDBx:U23>
         <PDBx:U33>0.9578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3730">
         <PDBx:U11>0.5927</PDBx:U11>
         <PDBx:U12>-0.0526</PDBx:U12>
         <PDBx:U13>0.2917</PDBx:U13>
         <PDBx:U22>0.8102</PDBx:U22>
         <PDBx:U23>0.0438</PDBx:U23>
         <PDBx:U33>0.9676</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3731">
         <PDBx:U11>0.5800</PDBx:U11>
         <PDBx:U12>-0.0382</PDBx:U12>
         <PDBx:U13>0.2622</PDBx:U13>
         <PDBx:U22>0.7628</PDBx:U22>
         <PDBx:U23>0.0715</PDBx:U23>
         <PDBx:U33>0.9590</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3732">
         <PDBx:U11>0.5427</PDBx:U11>
         <PDBx:U12>-0.0667</PDBx:U12>
         <PDBx:U13>0.2758</PDBx:U13>
         <PDBx:U22>0.7837</PDBx:U22>
         <PDBx:U23>0.0543</PDBx:U23>
         <PDBx:U33>0.8914</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3733">
         <PDBx:U11>0.4790</PDBx:U11>
         <PDBx:U12>-0.0801</PDBx:U12>
         <PDBx:U13>0.2807</PDBx:U13>
         <PDBx:U22>0.7292</PDBx:U22>
         <PDBx:U23>0.0482</PDBx:U23>
         <PDBx:U33>0.8089</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3734">
         <PDBx:U11>0.4851</PDBx:U11>
         <PDBx:U12>-0.0833</PDBx:U12>
         <PDBx:U13>0.2772</PDBx:U13>
         <PDBx:U22>0.7072</PDBx:U22>
         <PDBx:U23>0.0471</PDBx:U23>
         <PDBx:U33>0.8036</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3735">
         <PDBx:U11>0.5061</PDBx:U11>
         <PDBx:U12>-0.0904</PDBx:U12>
         <PDBx:U13>0.2852</PDBx:U13>
         <PDBx:U22>0.7286</PDBx:U22>
         <PDBx:U23>0.0396</PDBx:U23>
         <PDBx:U33>0.8162</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3736">
         <PDBx:U11>0.4520</PDBx:U11>
         <PDBx:U12>-0.0933</PDBx:U12>
         <PDBx:U13>0.2727</PDBx:U13>
         <PDBx:U22>0.7212</PDBx:U22>
         <PDBx:U23>0.0541</PDBx:U23>
         <PDBx:U33>0.7613</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3737">
         <PDBx:U11>0.4773</PDBx:U11>
         <PDBx:U12>-0.0922</PDBx:U12>
         <PDBx:U13>0.2780</PDBx:U13>
         <PDBx:U22>0.7791</PDBx:U22>
         <PDBx:U23>0.0538</PDBx:U23>
         <PDBx:U33>0.7974</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3738">
         <PDBx:U11>0.4827</PDBx:U11>
         <PDBx:U12>-0.1067</PDBx:U12>
         <PDBx:U13>0.2754</PDBx:U13>
         <PDBx:U22>0.7560</PDBx:U22>
         <PDBx:U23>0.0522</PDBx:U23>
         <PDBx:U33>0.7716</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3739">
         <PDBx:U11>0.4061</PDBx:U11>
         <PDBx:U12>-0.1061</PDBx:U12>
         <PDBx:U13>0.2719</PDBx:U13>
         <PDBx:U22>0.7291</PDBx:U22>
         <PDBx:U23>0.0600</PDBx:U23>
         <PDBx:U33>0.7075</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3740">
         <PDBx:U11>0.3903</PDBx:U11>
         <PDBx:U12>-0.0780</PDBx:U12>
         <PDBx:U13>0.2655</PDBx:U13>
         <PDBx:U22>0.5886</PDBx:U22>
         <PDBx:U23>0.0545</PDBx:U23>
         <PDBx:U33>0.7086</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3741">
         <PDBx:U11>0.4275</PDBx:U11>
         <PDBx:U12>-0.0800</PDBx:U12>
         <PDBx:U13>0.2610</PDBx:U13>
         <PDBx:U22>0.6003</PDBx:U22>
         <PDBx:U23>0.0543</PDBx:U23>
         <PDBx:U33>0.7371</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3742">
         <PDBx:U11>0.4525</PDBx:U11>
         <PDBx:U12>-0.0720</PDBx:U12>
         <PDBx:U13>0.2724</PDBx:U13>
         <PDBx:U22>0.6106</PDBx:U22>
         <PDBx:U23>0.0466</PDBx:U23>
         <PDBx:U33>0.7796</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3743">
         <PDBx:U11>0.4668</PDBx:U11>
         <PDBx:U12>-0.0771</PDBx:U12>
         <PDBx:U13>0.2739</PDBx:U13>
         <PDBx:U22>0.6102</PDBx:U22>
         <PDBx:U23>0.0420</PDBx:U23>
         <PDBx:U33>0.7863</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3744">
         <PDBx:U11>0.4289</PDBx:U11>
         <PDBx:U12>-0.0747</PDBx:U12>
         <PDBx:U13>0.2458</PDBx:U13>
         <PDBx:U22>0.5834</PDBx:U22>
         <PDBx:U23>0.0646</PDBx:U23>
         <PDBx:U33>0.7356</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3745">
         <PDBx:U11>0.4017</PDBx:U11>
         <PDBx:U12>-0.0770</PDBx:U12>
         <PDBx:U13>0.2388</PDBx:U13>
         <PDBx:U22>0.5332</PDBx:U22>
         <PDBx:U23>0.0655</PDBx:U23>
         <PDBx:U33>0.6983</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3746">
         <PDBx:U11>0.3722</PDBx:U11>
         <PDBx:U12>-0.0934</PDBx:U12>
         <PDBx:U13>0.2366</PDBx:U13>
         <PDBx:U22>0.5113</PDBx:U22>
         <PDBx:U23>0.0630</PDBx:U23>
         <PDBx:U33>0.6449</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3747">
         <PDBx:U11>0.3636</PDBx:U11>
         <PDBx:U12>-0.0693</PDBx:U12>
         <PDBx:U13>0.2249</PDBx:U13>
         <PDBx:U22>0.4812</PDBx:U22>
         <PDBx:U23>0.0754</PDBx:U23>
         <PDBx:U33>0.6603</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3748">
         <PDBx:U11>0.5249</PDBx:U11>
         <PDBx:U12>-0.0600</PDBx:U12>
         <PDBx:U13>0.2801</PDBx:U13>
         <PDBx:U22>0.6872</PDBx:U22>
         <PDBx:U23>0.0455</PDBx:U23>
         <PDBx:U33>0.8760</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3749">
         <PDBx:U11>0.6167</PDBx:U11>
         <PDBx:U12>-0.0522</PDBx:U12>
         <PDBx:U13>0.2926</PDBx:U13>
         <PDBx:U22>0.7675</PDBx:U22>
         <PDBx:U23>0.0374</PDBx:U23>
         <PDBx:U33>0.9870</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3750">
         <PDBx:U11>0.6043</PDBx:U11>
         <PDBx:U12>-0.0617</PDBx:U12>
         <PDBx:U13>0.3055</PDBx:U13>
         <PDBx:U22>0.7660</PDBx:U22>
         <PDBx:U23>0.0236</PDBx:U23>
         <PDBx:U33>0.9657</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3751">
         <PDBx:U11>0.6255</PDBx:U11>
         <PDBx:U12>-0.0638</PDBx:U12>
         <PDBx:U13>0.3114</PDBx:U13>
         <PDBx:U22>0.7707</PDBx:U22>
         <PDBx:U23>0.0160</PDBx:U23>
         <PDBx:U33>0.9864</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3752">
         <PDBx:U11>0.7106</PDBx:U11>
         <PDBx:U12>-0.0381</PDBx:U12>
         <PDBx:U13>0.2991</PDBx:U13>
         <PDBx:U22>0.8704</PDBx:U22>
         <PDBx:U23>0.0388</PDBx:U23>
         <PDBx:U33>1.1084</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3753">
         <PDBx:U11>0.7249</PDBx:U11>
         <PDBx:U12>-0.0269</PDBx:U12>
         <PDBx:U13>0.2888</PDBx:U13>
         <PDBx:U22>0.8682</PDBx:U22>
         <PDBx:U23>0.0525</PDBx:U23>
         <PDBx:U33>1.1353</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3754">
         <PDBx:U11>0.7572</PDBx:U11>
         <PDBx:U12>-0.0270</PDBx:U12>
         <PDBx:U13>0.2772</PDBx:U13>
         <PDBx:U22>0.8761</PDBx:U22>
         <PDBx:U23>0.0605</PDBx:U23>
         <PDBx:U33>1.1585</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3755">
         <PDBx:U11>0.7526</PDBx:U11>
         <PDBx:U12>-0.0152</PDBx:U12>
         <PDBx:U13>0.2885</PDBx:U13>
         <PDBx:U22>0.9017</PDBx:U22>
         <PDBx:U23>0.0600</PDBx:U23>
         <PDBx:U33>1.1836</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3756">
         <PDBx:U11>0.7497</PDBx:U11>
         <PDBx:U12>-0.0157</PDBx:U12>
         <PDBx:U13>0.2705</PDBx:U13>
         <PDBx:U22>0.8596</PDBx:U22>
         <PDBx:U23>0.0726</PDBx:U23>
         <PDBx:U33>1.1650</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3757">
         <PDBx:U11>0.7603</PDBx:U11>
         <PDBx:U12>-0.0089</PDBx:U12>
         <PDBx:U13>0.2769</PDBx:U13>
         <PDBx:U22>0.8875</PDBx:U22>
         <PDBx:U23>0.0731</PDBx:U23>
         <PDBx:U33>1.1933</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3758">
         <PDBx:U11>0.5479</PDBx:U11>
         <PDBx:U12>-0.0678</PDBx:U12>
         <PDBx:U13>0.3100</PDBx:U13>
         <PDBx:U22>0.7379</PDBx:U22>
         <PDBx:U23>0.0204</PDBx:U23>
         <PDBx:U33>0.9021</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3759">
         <PDBx:U11>0.5424</PDBx:U11>
         <PDBx:U12>-0.0790</PDBx:U12>
         <PDBx:U13>0.3202</PDBx:U13>
         <PDBx:U22>0.7444</PDBx:U22>
         <PDBx:U23>0.0098</PDBx:U23>
         <PDBx:U33>0.8822</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3760">
         <PDBx:U11>0.6280</PDBx:U11>
         <PDBx:U12>-0.0927</PDBx:U12>
         <PDBx:U13>0.3092</PDBx:U13>
         <PDBx:U22>0.8177</PDBx:U22>
         <PDBx:U23>0.0148</PDBx:U23>
         <PDBx:U33>0.9408</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3761">
         <PDBx:U11>0.7624</PDBx:U11>
         <PDBx:U12>-0.0913</PDBx:U12>
         <PDBx:U13>0.2961</PDBx:U13>
         <PDBx:U22>0.9331</PDBx:U22>
         <PDBx:U23>0.0236</PDBx:U23>
         <PDBx:U33>1.0718</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3762">
         <PDBx:U11>0.5464</PDBx:U11>
         <PDBx:U12>-0.0823</PDBx:U12>
         <PDBx:U13>0.3256</PDBx:U13>
         <PDBx:U22>0.7824</PDBx:U22>
         <PDBx:U23>0.0087</PDBx:U23>
         <PDBx:U33>0.8840</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3763">
         <PDBx:U11>0.5465</PDBx:U11>
         <PDBx:U12>-0.0787</PDBx:U12>
         <PDBx:U13>0.3449</PDBx:U13>
         <PDBx:U22>0.7988</PDBx:U22>
         <PDBx:U23>-0.0064</PDBx:U23>
         <PDBx:U33>0.8954</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3764">
         <PDBx:U11>0.5940</PDBx:U11>
         <PDBx:U12>-0.0771</PDBx:U12>
         <PDBx:U13>0.3496</PDBx:U13>
         <PDBx:U22>0.8814</PDBx:U22>
         <PDBx:U23>-0.0056</PDBx:U23>
         <PDBx:U33>0.9493</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3765">
         <PDBx:U11>0.6005</PDBx:U11>
         <PDBx:U12>-0.0891</PDBx:U12>
         <PDBx:U13>0.3381</PDBx:U13>
         <PDBx:U22>0.9006</PDBx:U22>
         <PDBx:U23>0.0062</PDBx:U23>
         <PDBx:U33>0.9350</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3766">
         <PDBx:U11>0.6157</PDBx:U11>
         <PDBx:U12>-0.1032</PDBx:U12>
         <PDBx:U13>0.3382</PDBx:U13>
         <PDBx:U22>0.9188</PDBx:U22>
         <PDBx:U23>0.0069</PDBx:U23>
         <PDBx:U33>0.9261</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3767">
         <PDBx:U11>0.6066</PDBx:U11>
         <PDBx:U12>-0.1125</PDBx:U12>
         <PDBx:U13>0.3273</PDBx:U13>
         <PDBx:U22>0.9199</PDBx:U22>
         <PDBx:U23>0.0192</PDBx:U23>
         <PDBx:U33>0.9013</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3768">
         <PDBx:U11>0.6343</PDBx:U11>
         <PDBx:U12>-0.1082</PDBx:U12>
         <PDBx:U13>0.3492</PDBx:U13>
         <PDBx:U22>0.9288</PDBx:U22>
         <PDBx:U23>-0.0048</PDBx:U23>
         <PDBx:U33>0.9364</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3769">
         <PDBx:U11>0.6640</PDBx:U11>
         <PDBx:U12>-0.1054</PDBx:U12>
         <PDBx:U13>0.3144</PDBx:U13>
         <PDBx:U22>0.8646</PDBx:U22>
         <PDBx:U23>0.0097</PDBx:U23>
         <PDBx:U33>0.9581</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3770">
         <PDBx:U11>0.6415</PDBx:U11>
         <PDBx:U12>-0.1187</PDBx:U12>
         <PDBx:U13>0.3035</PDBx:U13>
         <PDBx:U22>0.8328</PDBx:U22>
         <PDBx:U23>0.0159</PDBx:U23>
         <PDBx:U33>0.9103</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3771">
         <PDBx:U11>0.5822</PDBx:U11>
         <PDBx:U12>-0.1185</PDBx:U12>
         <PDBx:U13>0.2997</PDBx:U13>
         <PDBx:U22>0.7452</PDBx:U22>
         <PDBx:U23>0.0141</PDBx:U23>
         <PDBx:U33>0.8504</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3772">
         <PDBx:U11>0.6044</PDBx:U11>
         <PDBx:U12>-0.1290</PDBx:U12>
         <PDBx:U13>0.3022</PDBx:U13>
         <PDBx:U22>0.7603</PDBx:U22>
         <PDBx:U23>0.0091</PDBx:U23>
         <PDBx:U33>0.8578</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3773">
         <PDBx:U11>0.6224</PDBx:U11>
         <PDBx:U12>-0.1213</PDBx:U12>
         <PDBx:U13>0.2867</PDBx:U13>
         <PDBx:U22>0.8198</PDBx:U22>
         <PDBx:U23>0.0309</PDBx:U23>
         <PDBx:U33>0.8816</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3774">
         <PDBx:U11>0.6198</PDBx:U11>
         <PDBx:U12>-0.1202</PDBx:U12>
         <PDBx:U13>0.2884</PDBx:U13>
         <PDBx:U22>0.8445</PDBx:U22>
         <PDBx:U23>0.0347</PDBx:U23>
         <PDBx:U33>0.8832</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3775">
         <PDBx:U11>0.5580</PDBx:U11>
         <PDBx:U12>-0.1251</PDBx:U12>
         <PDBx:U13>0.2716</PDBx:U13>
         <PDBx:U22>0.7860</PDBx:U22>
         <PDBx:U23>0.0485</PDBx:U23>
         <PDBx:U33>0.8090</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3776">
         <PDBx:U11>0.6568</PDBx:U11>
         <PDBx:U12>-0.1280</PDBx:U12>
         <PDBx:U13>0.3018</PDBx:U13>
         <PDBx:U22>0.9018</PDBx:U22>
         <PDBx:U23>0.0280</PDBx:U23>
         <PDBx:U33>0.9129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3777">
         <PDBx:U11>0.5279</PDBx:U11>
         <PDBx:U12>-0.1069</PDBx:U12>
         <PDBx:U13>0.2936</PDBx:U13>
         <PDBx:U22>0.6748</PDBx:U22>
         <PDBx:U23>0.0187</PDBx:U23>
         <PDBx:U33>0.8121</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3778">
         <PDBx:U11>0.5652</PDBx:U11>
         <PDBx:U12>-0.1051</PDBx:U12>
         <PDBx:U13>0.2908</PDBx:U13>
         <PDBx:U22>0.6857</PDBx:U22>
         <PDBx:U23>0.0174</PDBx:U23>
         <PDBx:U33>0.8524</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3779">
         <PDBx:U11>0.6646</PDBx:U11>
         <PDBx:U12>-0.1051</PDBx:U12>
         <PDBx:U13>0.3141</PDBx:U13>
         <PDBx:U22>0.7702</PDBx:U22>
         <PDBx:U23>-0.0004</PDBx:U23>
         <PDBx:U33>0.9669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3780">
         <PDBx:U11>0.6341</PDBx:U11>
         <PDBx:U12>-0.1128</PDBx:U12>
         <PDBx:U13>0.3190</PDBx:U13>
         <PDBx:U22>0.7197</PDBx:U22>
         <PDBx:U23>-0.0073</PDBx:U23>
         <PDBx:U33>0.9310</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3781">
         <PDBx:U11>0.5282</PDBx:U11>
         <PDBx:U12>-0.0911</PDBx:U12>
         <PDBx:U13>0.2825</PDBx:U13>
         <PDBx:U22>0.6336</PDBx:U22>
         <PDBx:U23>0.0260</PDBx:U23>
         <PDBx:U33>0.8326</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3782">
         <PDBx:U11>0.4757</PDBx:U11>
         <PDBx:U12>-0.0921</PDBx:U12>
         <PDBx:U13>0.2640</PDBx:U13>
         <PDBx:U22>0.5740</PDBx:U22>
         <PDBx:U23>0.0386</PDBx:U23>
         <PDBx:U33>0.7679</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3783">
         <PDBx:U11>0.3877</PDBx:U11>
         <PDBx:U12>-0.0766</PDBx:U12>
         <PDBx:U13>0.2583</PDBx:U13>
         <PDBx:U22>0.4741</PDBx:U22>
         <PDBx:U23>0.0465</PDBx:U23>
         <PDBx:U33>0.6985</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3784">
         <PDBx:U11>0.4037</PDBx:U11>
         <PDBx:U12>-0.1012</PDBx:U12>
         <PDBx:U13>0.2576</PDBx:U13>
         <PDBx:U22>0.4876</PDBx:U22>
         <PDBx:U23>0.0382</PDBx:U23>
         <PDBx:U33>0.6812</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3785">
         <PDBx:U11>0.7729</PDBx:U11>
         <PDBx:U12>-0.0967</PDBx:U12>
         <PDBx:U13>0.3307</PDBx:U13>
         <PDBx:U22>0.8863</PDBx:U22>
         <PDBx:U23>-0.0094</PDBx:U23>
         <PDBx:U33>1.0962</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3786">
         <PDBx:U11>0.8573</PDBx:U11>
         <PDBx:U12>-0.0959</PDBx:U12>
         <PDBx:U13>0.3567</PDBx:U13>
         <PDBx:U22>0.9552</PDBx:U22>
         <PDBx:U23>-0.0298</PDBx:U23>
         <PDBx:U33>1.1992</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3787">
         <PDBx:U11>0.9107</PDBx:U11>
         <PDBx:U12>-0.1119</PDBx:U12>
         <PDBx:U13>0.3695</PDBx:U13>
         <PDBx:U22>1.0181</PDBx:U22>
         <PDBx:U23>-0.0447</PDBx:U23>
         <PDBx:U33>1.2320</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3788">
         <PDBx:U11>0.9497</PDBx:U11>
         <PDBx:U12>-0.1185</PDBx:U12>
         <PDBx:U13>0.3882</PDBx:U13>
         <PDBx:U22>1.0393</PDBx:U22>
         <PDBx:U23>-0.0637</PDBx:U23>
         <PDBx:U33>1.2737</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3789">
         <PDBx:U11>0.8798</PDBx:U11>
         <PDBx:U12>-0.0802</PDBx:U12>
         <PDBx:U13>0.3689</PDBx:U13>
         <PDBx:U22>0.9853</PDBx:U22>
         <PDBx:U23>-0.0339</PDBx:U23>
         <PDBx:U33>1.2528</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3790">
         <PDBx:U11>0.8871</PDBx:U11>
         <PDBx:U12>-0.0647</PDBx:U12>
         <PDBx:U13>0.3572</PDBx:U13>
         <PDBx:U22>0.9831</PDBx:U22>
         <PDBx:U23>-0.0187</PDBx:U23>
         <PDBx:U33>1.2805</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3791">
         <PDBx:U11>0.9437</PDBx:U11>
         <PDBx:U12>-0.0492</PDBx:U12>
         <PDBx:U13>0.3692</PDBx:U13>
         <PDBx:U22>1.0469</PDBx:U22>
         <PDBx:U23>-0.0220</PDBx:U23>
         <PDBx:U33>1.3693</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3792">
         <PDBx:U11>0.9933</PDBx:U11>
         <PDBx:U12>-0.0466</PDBx:U12>
         <PDBx:U13>0.3906</PDBx:U13>
         <PDBx:U22>1.0931</PDBx:U22>
         <PDBx:U23>-0.0390</PDBx:U23>
         <PDBx:U33>1.4365</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3793">
         <PDBx:U11>0.9360</PDBx:U11>
         <PDBx:U12>-0.0390</PDBx:U12>
         <PDBx:U13>0.3552</PDBx:U13>
         <PDBx:U22>1.0498</PDBx:U22>
         <PDBx:U23>-0.0065</PDBx:U23>
         <PDBx:U33>1.3690</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3794">
         <PDBx:U11>0.9145</PDBx:U11>
         <PDBx:U12>-0.1189</PDBx:U12>
         <PDBx:U13>0.3598</PDBx:U13>
         <PDBx:U22>1.0492</PDBx:U22>
         <PDBx:U23>-0.0366</PDBx:U23>
         <PDBx:U33>1.2144</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3795">
         <PDBx:U11>0.9411</PDBx:U11>
         <PDBx:U12>-0.1345</PDBx:U12>
         <PDBx:U13>0.3706</PDBx:U13>
         <PDBx:U22>1.0862</PDBx:U22>
         <PDBx:U23>-0.0485</PDBx:U23>
         <PDBx:U33>1.2191</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3796">
         <PDBx:U11>0.9412</PDBx:U11>
         <PDBx:U12>-0.1503</PDBx:U12>
         <PDBx:U13>0.3636</PDBx:U13>
         <PDBx:U22>1.0696</PDBx:U22>
         <PDBx:U23>-0.0478</PDBx:U23>
         <PDBx:U33>1.1937</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3797">
         <PDBx:U11>0.9125</PDBx:U11>
         <PDBx:U12>-0.1650</PDBx:U12>
         <PDBx:U13>0.3635</PDBx:U13>
         <PDBx:U22>1.0505</PDBx:U22>
         <PDBx:U23>-0.0495</PDBx:U23>
         <PDBx:U33>1.1394</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3798">
         <PDBx:U11>0.9268</PDBx:U11>
         <PDBx:U12>-0.1364</PDBx:U12>
         <PDBx:U13>0.3622</PDBx:U13>
         <PDBx:U22>1.1055</PDBx:U22>
         <PDBx:U23>-0.0375</PDBx:U23>
         <PDBx:U33>1.1922</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3799">
         <PDBx:U11>0.9403</PDBx:U11>
         <PDBx:U12>-0.1221</PDBx:U12>
         <PDBx:U13>0.3697</PDBx:U13>
         <PDBx:U22>1.1397</PDBx:U22>
         <PDBx:U23>-0.0392</PDBx:U23>
         <PDBx:U33>1.2296</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3800">
         <PDBx:U11>0.9688</PDBx:U11>
         <PDBx:U12>-0.1120</PDBx:U12>
         <PDBx:U13>0.3858</PDBx:U13>
         <PDBx:U22>1.1571</PDBx:U22>
         <PDBx:U23>-0.0530</PDBx:U23>
         <PDBx:U33>1.2836</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3801">
         <PDBx:U11>0.9386</PDBx:U11>
         <PDBx:U12>-0.1209</PDBx:U12>
         <PDBx:U13>0.3594</PDBx:U13>
         <PDBx:U22>1.1655</PDBx:U22>
         <PDBx:U23>-0.0265</PDBx:U23>
         <PDBx:U33>1.2225</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>C</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>C</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3802">
         <PDBx:U11>1.0494</PDBx:U11>
         <PDBx:U12>-0.1525</PDBx:U12>
         <PDBx:U13>0.0489</PDBx:U13>
         <PDBx:U22>0.5744</PDBx:U22>
         <PDBx:U23>-0.1827</PDBx:U23>
         <PDBx:U33>1.2528</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3803">
         <PDBx:U11>0.9515</PDBx:U11>
         <PDBx:U12>-0.1629</PDBx:U12>
         <PDBx:U13>0.0454</PDBx:U13>
         <PDBx:U22>0.5604</PDBx:U22>
         <PDBx:U23>-0.1746</PDBx:U23>
         <PDBx:U33>1.1428</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3804">
         <PDBx:U11>0.8558</PDBx:U11>
         <PDBx:U12>-0.1395</PDBx:U12>
         <PDBx:U13>0.0386</PDBx:U13>
         <PDBx:U22>0.5141</PDBx:U22>
         <PDBx:U23>-0.2041</PDBx:U23>
         <PDBx:U33>1.0007</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3805">
         <PDBx:U11>0.9239</PDBx:U11>
         <PDBx:U12>-0.1060</PDBx:U12>
         <PDBx:U13>0.0465</PDBx:U13>
         <PDBx:U22>0.5660</PDBx:U22>
         <PDBx:U23>-0.2163</PDBx:U23>
         <PDBx:U33>1.0476</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3806">
         <PDBx:U11>0.9576</PDBx:U11>
         <PDBx:U12>-0.1534</PDBx:U12>
         <PDBx:U13>0.0608</PDBx:U13>
         <PDBx:U22>0.5957</PDBx:U22>
         <PDBx:U23>-0.1178</PDBx:U23>
         <PDBx:U33>1.1512</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3807">
         <PDBx:U11>1.0198</PDBx:U11>
         <PDBx:U12>-0.1808</PDBx:U12>
         <PDBx:U13>0.0701</PDBx:U13>
         <PDBx:U22>0.6357</PDBx:U22>
         <PDBx:U23>-0.0825</PDBx:U23>
         <PDBx:U33>1.2570</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3808">
         <PDBx:U11>0.9500</PDBx:U11>
         <PDBx:U12>-0.1735</PDBx:U12>
         <PDBx:U13>0.0813</PDBx:U13>
         <PDBx:U22>0.6209</PDBx:U22>
         <PDBx:U23>-0.0362</PDBx:U23>
         <PDBx:U33>1.1824</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3809">
         <PDBx:U11>0.9614</PDBx:U11>
         <PDBx:U12>-0.1463</PDBx:U12>
         <PDBx:U13>0.1010</PDBx:U13>
         <PDBx:U22>0.5988</PDBx:U22>
         <PDBx:U23>0.0063</PDBx:U23>
         <PDBx:U33>1.1853</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3810">
         <PDBx:U11>0.8831</PDBx:U11>
         <PDBx:U12>-0.1437</PDBx:U12>
         <PDBx:U13>0.1125</PDBx:U13>
         <PDBx:U22>0.5691</PDBx:U22>
         <PDBx:U23>0.0498</PDBx:U23>
         <PDBx:U33>1.1063</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LYS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>688</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LYS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>3</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3811">
         <PDBx:U11>0.7904</PDBx:U11>
         <PDBx:U12>-0.1568</PDBx:U12>
         <PDBx:U13>0.0239</PDBx:U13>
         <PDBx:U22>0.5129</PDBx:U22>
         <PDBx:U23>-0.2132</PDBx:U23>
         <PDBx:U33>0.9217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3812">
         <PDBx:U11>0.7939</PDBx:U11>
         <PDBx:U12>-0.1409</PDBx:U12>
         <PDBx:U13>0.0173</PDBx:U13>
         <PDBx:U22>0.5712</PDBx:U22>
         <PDBx:U23>-0.2331</PDBx:U23>
         <PDBx:U33>0.8810</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3813">
         <PDBx:U11>0.6878</PDBx:U11>
         <PDBx:U12>-0.1103</PDBx:U12>
         <PDBx:U13>0.0306</PDBx:U13>
         <PDBx:U22>0.4947</PDBx:U22>
         <PDBx:U23>-0.1999</PDBx:U23>
         <PDBx:U33>0.7557</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3814">
         <PDBx:U11>0.6623</PDBx:U11>
         <PDBx:U12>-0.0831</PDBx:U12>
         <PDBx:U13>0.0381</PDBx:U13>
         <PDBx:U22>0.4781</PDBx:U22>
         <PDBx:U23>-0.2142</PDBx:U23>
         <PDBx:U33>0.7073</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3815">
         <PDBx:U11>0.7702</PDBx:U11>
         <PDBx:U12>-0.1663</PDBx:U12>
         <PDBx:U13>-0.0032</PDBx:U13>
         <PDBx:U22>0.6083</PDBx:U22>
         <PDBx:U23>-0.2368</PDBx:U23>
         <PDBx:U33>0.8481</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3816">
         <PDBx:U11>0.8428</PDBx:U11>
         <PDBx:U12>-0.1933</PDBx:U12>
         <PDBx:U13>-0.0214</PDBx:U13>
         <PDBx:U22>0.6619</PDBx:U22>
         <PDBx:U23>-0.2717</PDBx:U23>
         <PDBx:U33>0.9358</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3817">
         <PDBx:U11>0.6938</PDBx:U11>
         <PDBx:U12>-0.1518</PDBx:U12>
         <PDBx:U13>-0.0084</PDBx:U13>
         <PDBx:U22>0.5916</PDBx:U22>
         <PDBx:U23>-0.2435</PDBx:U23>
         <PDBx:U33>0.7249</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3818">
         <PDBx:U11>0.8111</PDBx:U11>
         <PDBx:U12>-0.2081</PDBx:U12>
         <PDBx:U13>-0.0448</PDBx:U13>
         <PDBx:U22>0.6897</PDBx:U22>
         <PDBx:U23>-0.2607</PDBx:U23>
         <PDBx:U33>0.8944</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ILE</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>689</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ILE</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>4</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3819">
         <PDBx:U11>0.6095</PDBx:U11>
         <PDBx:U12>-0.1141</PDBx:U12>
         <PDBx:U13>0.0324</PDBx:U13>
         <PDBx:U22>0.4363</PDBx:U22>
         <PDBx:U23>-0.1577</PDBx:U23>
         <PDBx:U33>0.6884</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3820">
         <PDBx:U11>0.5496</PDBx:U11>
         <PDBx:U12>-0.0878</PDBx:U12>
         <PDBx:U13>0.0404</PDBx:U13>
         <PDBx:U22>0.4003</PDBx:U22>
         <PDBx:U23>-0.1253</PDBx:U23>
         <PDBx:U33>0.6145</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3821">
         <PDBx:U11>0.5717</PDBx:U11>
         <PDBx:U12>-0.0566</PDBx:U12>
         <PDBx:U13>0.0568</PDBx:U13>
         <PDBx:U22>0.3810</PDBx:U22>
         <PDBx:U23>-0.1274</PDBx:U23>
         <PDBx:U33>0.6376</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3822">
         <PDBx:U11>0.5428</PDBx:U11>
         <PDBx:U12>-0.0311</PDBx:U12>
         <PDBx:U13>0.0611</PDBx:U13>
         <PDBx:U22>0.3816</PDBx:U22>
         <PDBx:U23>-0.1243</PDBx:U23>
         <PDBx:U33>0.5916</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3823">
         <PDBx:U11>0.5101</PDBx:U11>
         <PDBx:U12>-0.0927</PDBx:U12>
         <PDBx:U13>0.0416</PDBx:U13>
         <PDBx:U22>0.3663</PDBx:U22>
         <PDBx:U23>-0.0851</PDBx:U23>
         <PDBx:U33>0.5904</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3824">
         <PDBx:U11>0.5167</PDBx:U11>
         <PDBx:U12>-0.0655</PDBx:U12>
         <PDBx:U13>0.0470</PDBx:U13>
         <PDBx:U22>0.3876</PDBx:U22>
         <PDBx:U23>-0.0515</PDBx:U23>
         <PDBx:U33>0.5849</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3825">
         <PDBx:U11>0.4101</PDBx:U11>
         <PDBx:U12>-0.0579</PDBx:U12>
         <PDBx:U13>0.0348</PDBx:U13>
         <PDBx:U22>0.3344</PDBx:U22>
         <PDBx:U23>-0.0540</PDBx:U23>
         <PDBx:U33>0.4529</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3826">
         <PDBx:U11>0.5006</PDBx:U11>
         <PDBx:U12>-0.0697</PDBx:U12>
         <PDBx:U13>0.0468</PDBx:U13>
         <PDBx:U22>0.3792</PDBx:U22>
         <PDBx:U23>-0.0196</PDBx:U23>
         <PDBx:U33>0.5788</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>690</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>5</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3827">
         <PDBx:U11>0.6225</PDBx:U11>
         <PDBx:U12>-0.0596</PDBx:U12>
         <PDBx:U13>0.0645</PDBx:U13>
         <PDBx:U22>0.3641</PDBx:U22>
         <PDBx:U23>-0.1310</PDBx:U23>
         <PDBx:U33>0.7128</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3828">
         <PDBx:U11>0.6975</PDBx:U11>
         <PDBx:U12>-0.0293</PDBx:U12>
         <PDBx:U13>0.0766</PDBx:U13>
         <PDBx:U22>0.3842</PDBx:U22>
         <PDBx:U23>-0.1350</PDBx:U23>
         <PDBx:U33>0.7926</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3829">
         <PDBx:U11>0.7522</PDBx:U11>
         <PDBx:U12>-0.0066</PDBx:U12>
         <PDBx:U13>0.0760</PDBx:U13>
         <PDBx:U22>0.4547</PDBx:U22>
         <PDBx:U23>-0.1785</PDBx:U23>
         <PDBx:U33>0.8256</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3830">
         <PDBx:U11>0.7354</PDBx:U11>
         <PDBx:U12>0.0298</PDBx:U12>
         <PDBx:U13>0.0853</PDBx:U13>
         <PDBx:U22>0.4434</PDBx:U22>
         <PDBx:U23>-0.1757</PDBx:U23>
         <PDBx:U33>0.8020</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3831">
         <PDBx:U11>0.7886</PDBx:U11>
         <PDBx:U12>-0.0464</PDBx:U12>
         <PDBx:U13>0.0788</PDBx:U13>
         <PDBx:U22>0.3935</PDBx:U22>
         <PDBx:U23>-0.1375</PDBx:U23>
         <PDBx:U33>0.9154</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3832">
         <PDBx:U11>0.9683</PDBx:U11>
         <PDBx:U12>-0.0161</PDBx:U12>
         <PDBx:U13>0.0864</PDBx:U13>
         <PDBx:U22>0.5009</PDBx:U22>
         <PDBx:U23>-0.1454</PDBx:U23>
         <PDBx:U33>1.1023</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3833">
         <PDBx:U11>0.9960</PDBx:U11>
         <PDBx:U12>0.0275</PDBx:U12>
         <PDBx:U13>0.0947</PDBx:U13>
         <PDBx:U22>0.5400</PDBx:U22>
         <PDBx:U23>-0.1365</PDBx:U23>
         <PDBx:U33>1.1148</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>ND1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>ND1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3834">
         <PDBx:U11>1.1231</PDBx:U11>
         <PDBx:U12>-0.0224</PDBx:U12>
         <PDBx:U13>0.0842</PDBx:U13>
         <PDBx:U22>0.5682</PDBx:U22>
         <PDBx:U23>-0.1613</PDBx:U23>
         <PDBx:U33>1.2812</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3835">
         <PDBx:U11>1.1077</PDBx:U11>
         <PDBx:U12>0.0507</PDBx:U12>
         <PDBx:U13>0.0978</PDBx:U13>
         <PDBx:U22>0.5748</PDBx:U22>
         <PDBx:U23>-0.1471</PDBx:U23>
         <PDBx:U33>1.2391</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3836">
         <PDBx:U11>1.1869</PDBx:U11>
         <PDBx:U12>0.0205</PDBx:U12>
         <PDBx:U13>0.0908</PDBx:U13>
         <PDBx:U22>0.5879</PDBx:U22>
         <PDBx:U23>-0.1622</PDBx:U23>
         <PDBx:U33>1.3413</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>HIS</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>691</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>HIS</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>6</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3837">
         <PDBx:U11>0.7761</PDBx:U11>
         <PDBx:U12>-0.0264</PDBx:U12>
         <PDBx:U13>0.0649</PDBx:U13>
         <PDBx:U22>0.4933</PDBx:U22>
         <PDBx:U23>-0.2189</PDBx:U23>
         <PDBx:U33>0.8382</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3838">
         <PDBx:U11>0.8121</PDBx:U11>
         <PDBx:U12>-0.0052</PDBx:U12>
         <PDBx:U13>0.0654</PDBx:U13>
         <PDBx:U22>0.5515</PDBx:U22>
         <PDBx:U23>-0.2647</PDBx:U23>
         <PDBx:U33>0.8477</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3839">
         <PDBx:U11>0.7736</PDBx:U11>
         <PDBx:U12>0.0105</PDBx:U12>
         <PDBx:U13>0.0703</PDBx:U13>
         <PDBx:U22>0.6022</PDBx:U22>
         <PDBx:U23>-0.2509</PDBx:U23>
         <PDBx:U33>0.7830</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3840">
         <PDBx:U11>0.7578</PDBx:U11>
         <PDBx:U12>0.0459</PDBx:U12>
         <PDBx:U13>0.0824</PDBx:U13>
         <PDBx:U22>0.6055</PDBx:U22>
         <PDBx:U23>-0.2593</PDBx:U23>
         <PDBx:U33>0.7599</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3841">
         <PDBx:U11>0.9034</PDBx:U11>
         <PDBx:U12>-0.0324</PDBx:U12>
         <PDBx:U13>0.0493</PDBx:U13>
         <PDBx:U22>0.6427</PDBx:U22>
         <PDBx:U23>-0.3097</PDBx:U23>
         <PDBx:U33>0.9275</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3842">
         <PDBx:U11>1.0325</PDBx:U11>
         <PDBx:U12>-0.0100</PDBx:U12>
         <PDBx:U13>0.0500</PDBx:U13>
         <PDBx:U22>0.8066</PDBx:U22>
         <PDBx:U23>-0.3594</PDBx:U23>
         <PDBx:U33>1.0196</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3843">
         <PDBx:U11>1.0726</PDBx:U11>
         <PDBx:U12>-0.0371</PDBx:U12>
         <PDBx:U13>0.0345</PDBx:U13>
         <PDBx:U22>0.9098</PDBx:U22>
         <PDBx:U23>-0.3763</PDBx:U23>
         <PDBx:U33>1.0292</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3844">
         <PDBx:U11>1.1514</PDBx:U11>
         <PDBx:U12>-0.0727</PDBx:U12>
         <PDBx:U13>0.0141</PDBx:U13>
         <PDBx:U22>0.9472</PDBx:U22>
         <PDBx:U23>-0.3974</PDBx:U23>
         <PDBx:U33>1.1239</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3845">
         <PDBx:U11>1.1891</PDBx:U11>
         <PDBx:U12>-0.1003</PDBx:U12>
         <PDBx:U13>-0.0050</PDBx:U13>
         <PDBx:U22>1.0295</PDBx:U22>
         <PDBx:U23>-0.4098</PDBx:U23>
         <PDBx:U33>1.1426</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CZ</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CZ</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3846">
         <PDBx:U11>1.2412</PDBx:U11>
         <PDBx:U12>-0.1268</PDBx:U12>
         <PDBx:U13>-0.0254</PDBx:U13>
         <PDBx:U22>1.0494</PDBx:U22>
         <PDBx:U23>-0.4109</PDBx:U23>
         <PDBx:U33>1.2137</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3847">
         <PDBx:U11>1.1659</PDBx:U11>
         <PDBx:U12>-0.0972</PDBx:U12>
         <PDBx:U13>-0.0056</PDBx:U13>
         <PDBx:U22>1.0881</PDBx:U22>
         <PDBx:U23>-0.3999</PDBx:U23>
         <PDBx:U33>1.0802</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NH2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ARG</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>692</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NH2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ARG</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>7</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3848">
         <PDBx:U11>0.6863</PDBx:U11>
         <PDBx:U12>-0.0164</PDBx:U12>
         <PDBx:U13>0.0596</PDBx:U13>
         <PDBx:U22>0.5698</PDBx:U22>
         <PDBx:U23>-0.2289</PDBx:U23>
         <PDBx:U33>0.6854</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3849">
         <PDBx:U11>0.6202</PDBx:U11>
         <PDBx:U12>-0.0114</PDBx:U12>
         <PDBx:U13>0.0595</PDBx:U13>
         <PDBx:U22>0.5864</PDBx:U22>
         <PDBx:U23>-0.2124</PDBx:U23>
         <PDBx:U33>0.5969</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3850">
         <PDBx:U11>0.5575</PDBx:U11>
         <PDBx:U12>0.0171</PDBx:U12>
         <PDBx:U13>0.0710</PDBx:U13>
         <PDBx:U22>0.5389</PDBx:U22>
         <PDBx:U23>-0.1801</PDBx:U23>
         <PDBx:U33>0.5464</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3851">
         <PDBx:U11>0.6602</PDBx:U11>
         <PDBx:U12>0.0344</PDBx:U12>
         <PDBx:U13>0.0781</PDBx:U13>
         <PDBx:U22>0.7015</PDBx:U22>
         <PDBx:U23>-0.1796</PDBx:U23>
         <PDBx:U33>0.6385</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3852">
         <PDBx:U11>0.5925</PDBx:U11>
         <PDBx:U12>-0.0452</PDBx:U12>
         <PDBx:U13>0.0413</PDBx:U13>
         <PDBx:U22>0.5952</PDBx:U22>
         <PDBx:U23>-0.1880</PDBx:U23>
         <PDBx:U33>0.5626</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3853">
         <PDBx:U11>0.6154</PDBx:U11>
         <PDBx:U12>-0.0738</PDBx:U12>
         <PDBx:U13>0.0257</PDBx:U13>
         <PDBx:U22>0.6130</PDBx:U22>
         <PDBx:U23>-0.2168</PDBx:U23>
         <PDBx:U33>0.5755</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3854">
         <PDBx:U11>0.5160</PDBx:U11>
         <PDBx:U12>-0.1014</PDBx:U12>
         <PDBx:U13>0.0061</PDBx:U13>
         <PDBx:U22>0.5430</PDBx:U22>
         <PDBx:U23>-0.1887</PDBx:U23>
         <PDBx:U33>0.4766</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3855">
         <PDBx:U11>0.6852</PDBx:U11>
         <PDBx:U12>-0.0678</PDBx:U12>
         <PDBx:U13>0.0262</PDBx:U13>
         <PDBx:U22>0.7222</PDBx:U22>
         <PDBx:U23>-0.2557</PDBx:U23>
         <PDBx:U33>0.6091</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>693</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>8</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3856">
         <PDBx:U11>0.5480</PDBx:U11>
         <PDBx:U12>0.0214</PDBx:U12>
         <PDBx:U13>0.0726</PDBx:U13>
         <PDBx:U22>0.4813</PDBx:U22>
         <PDBx:U23>-0.1518</PDBx:U23>
         <PDBx:U33>0.5597</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3857">
         <PDBx:U11>0.5350</PDBx:U11>
         <PDBx:U12>0.0511</PDBx:U12>
         <PDBx:U13>0.0805</PDBx:U13>
         <PDBx:U22>0.4747</PDBx:U22>
         <PDBx:U23>-0.1232</PDBx:U23>
         <PDBx:U33>0.5580</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3858">
         <PDBx:U11>0.6583</PDBx:U11>
         <PDBx:U12>0.0898</PDBx:U12>
         <PDBx:U13>0.0950</PDBx:U13>
         <PDBx:U22>0.5791</PDBx:U22>
         <PDBx:U23>-0.1487</PDBx:U23>
         <PDBx:U33>0.6869</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3859">
         <PDBx:U11>0.6144</PDBx:U11>
         <PDBx:U12>0.1190</PDBx:U12>
         <PDBx:U13>0.1015</PDBx:U13>
         <PDBx:U22>0.5710</PDBx:U22>
         <PDBx:U23>-0.1360</PDBx:U23>
         <PDBx:U33>0.6494</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3860">
         <PDBx:U11>0.5656</PDBx:U11>
         <PDBx:U12>0.0488</PDBx:U12>
         <PDBx:U13>0.0795</PDBx:U13>
         <PDBx:U22>0.4540</PDBx:U22>
         <PDBx:U23>-0.0894</PDBx:U23>
         <PDBx:U33>0.6050</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3861">
         <PDBx:U11>0.4689</PDBx:U11>
         <PDBx:U12>0.0256</PDBx:U12>
         <PDBx:U13>0.0661</PDBx:U13>
         <PDBx:U22>0.3839</PDBx:U22>
         <PDBx:U23>-0.0582</PDBx:U23>
         <PDBx:U33>0.5048</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3862">
         <PDBx:U11>0.4877</PDBx:U11>
         <PDBx:U12>0.0239</PDBx:U12>
         <PDBx:U13>0.0702</PDBx:U13>
         <PDBx:U22>0.3516</PDBx:U22>
         <PDBx:U23>-0.0325</PDBx:U23>
         <PDBx:U33>0.5368</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3863">
         <PDBx:U11>0.4260</PDBx:U11>
         <PDBx:U12>0.0371</PDBx:U12>
         <PDBx:U13>0.0582</PDBx:U13>
         <PDBx:U22>0.4001</PDBx:U22>
         <PDBx:U23>-0.0352</PDBx:U23>
         <PDBx:U33>0.4552</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>LEU</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>694</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>LEU</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>9</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3864">
         <PDBx:U11>0.6933</PDBx:U11>
         <PDBx:U12>0.0905</PDBx:U12>
         <PDBx:U13>0.0976</PDBx:U13>
         <PDBx:U22>0.5574</PDBx:U22>
         <PDBx:U23>-0.1869</PDBx:U23>
         <PDBx:U33>0.7220</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3865">
         <PDBx:U11>0.7765</PDBx:U11>
         <PDBx:U12>0.1302</PDBx:U12>
         <PDBx:U13>0.1081</PDBx:U13>
         <PDBx:U22>0.5986</PDBx:U22>
         <PDBx:U23>-0.2158</PDBx:U23>
         <PDBx:U33>0.8129</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3866">
         <PDBx:U11>0.8032</PDBx:U11>
         <PDBx:U12>0.1521</PDBx:U12>
         <PDBx:U13>0.1158</PDBx:U13>
         <PDBx:U22>0.6905</PDBx:U22>
         <PDBx:U23>-0.2557</PDBx:U23>
         <PDBx:U33>0.8195</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3867">
         <PDBx:U11>0.7940</PDBx:U11>
         <PDBx:U12>0.1952</PDBx:U12>
         <PDBx:U13>0.1264</PDBx:U13>
         <PDBx:U22>0.6764</PDBx:U22>
         <PDBx:U23>-0.2770</PDBx:U23>
         <PDBx:U33>0.8167</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3868">
         <PDBx:U11>0.8083</PDBx:U11>
         <PDBx:U12>0.1192</PDBx:U12>
         <PDBx:U13>0.1032</PDBx:U13>
         <PDBx:U22>0.5312</PDBx:U22>
         <PDBx:U23>-0.2410</PDBx:U23>
         <PDBx:U33>0.8559</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3869">
         <PDBx:U11>0.8933</PDBx:U11>
         <PDBx:U12>0.1561</PDBx:U12>
         <PDBx:U13>0.1088</PDBx:U13>
         <PDBx:U22>0.5329</PDBx:U22>
         <PDBx:U23>-0.2450</PDBx:U23>
         <PDBx:U33>0.9615</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CG</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CG</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3870">
         <PDBx:U11>0.9775</PDBx:U11>
         <PDBx:U12>0.1395</PDBx:U12>
         <PDBx:U13>0.1000</PDBx:U13>
         <PDBx:U22>0.5166</PDBx:U22>
         <PDBx:U23>-0.2742</PDBx:U23>
         <PDBx:U33>1.0587</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CD</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CD</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3871">
         <PDBx:U11>1.0045</PDBx:U11>
         <PDBx:U12>0.1051</PDBx:U12>
         <PDBx:U13>0.0899</PDBx:U13>
         <PDBx:U22>0.5456</PDBx:U22>
         <PDBx:U23>-0.3019</PDBx:U23>
         <PDBx:U33>1.0781</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>OE1</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>OE1</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3872">
         <PDBx:U11>1.0228</PDBx:U11>
         <PDBx:U12>0.1626</PDBx:U12>
         <PDBx:U13>0.1010</PDBx:U13>
         <PDBx:U22>0.4725</PDBx:U22>
         <PDBx:U23>-0.2665</PDBx:U23>
         <PDBx:U33>1.1259</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>NE2</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>GLN</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>695</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>NE2</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>GLN</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>10</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3873">
         <PDBx:U11>0.7991</PDBx:U11>
         <PDBx:U12>0.1245</PDBx:U12>
         <PDBx:U13>0.1107</PDBx:U13>
         <PDBx:U22>0.7511</PDBx:U22>
         <PDBx:U23>-0.2648</PDBx:U23>
         <PDBx:U33>0.7906</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>N</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>N</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>N</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3874">
         <PDBx:U11>0.8431</PDBx:U11>
         <PDBx:U12>0.1418</PDBx:U12>
         <PDBx:U13>0.1204</PDBx:U13>
         <PDBx:U22>0.8696</PDBx:U22>
         <PDBx:U23>-0.2988</PDBx:U23>
         <PDBx:U33>0.8092</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CA</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CA</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3875">
         <PDBx:U11>0.8135</PDBx:U11>
         <PDBx:U12>0.1727</PDBx:U12>
         <PDBx:U13>0.1348</PDBx:U13>
         <PDBx:U22>0.9188</PDBx:U22>
         <PDBx:U23>-0.2771</PDBx:U23>
         <PDBx:U33>0.7909</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>C</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>C</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3876">
         <PDBx:U11>0.7517</PDBx:U11>
         <PDBx:U12>0.2073</PDBx:U12>
         <PDBx:U13>0.1499</PDBx:U13>
         <PDBx:U22>0.9026</PDBx:U22>
         <PDBx:U23>-0.3088</PDBx:U23>
         <PDBx:U33>0.7217</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>O</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>O</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>O</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
      <PDBx:atom_site_anisotrop id="3877">
         <PDBx:U11>0.8324</PDBx:U11>
         <PDBx:U12>0.1029</PDBx:U12>
         <PDBx:U13>0.1103</PDBx:U13>
         <PDBx:U22>0.9158</PDBx:U22>
         <PDBx:U23>-0.3017</PDBx:U23>
         <PDBx:U33>0.7669</PDBx:U33>
         <PDBx:pdbx_auth_asym_id>D</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_atom_id>CB</PDBx:pdbx_auth_atom_id>
         <PDBx:pdbx_auth_comp_id>ASP</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>696</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_label_alt_id xsi:nil="true" />
         <PDBx:pdbx_label_asym_id>D</PDBx:pdbx_label_asym_id>
         <PDBx:pdbx_label_atom_id>CB</PDBx:pdbx_label_atom_id>
         <PDBx:pdbx_label_comp_id>ASP</PDBx:pdbx_label_comp_id>
         <PDBx:pdbx_label_seq_id>11</PDBx:pdbx_label_seq_id>
         <PDBx:type_symbol>C</PDBx:type_symbol>
      </PDBx:atom_site_anisotrop>
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         <PDBx:name>Elemento, O.</PDBx:name>
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         <PDBx:pdbx_database_id_PubMed>27107013</PDBx:pdbx_database_id_PubMed>
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         <PDBx:pdbx_diffrn_protocol>SINGLE WAVELENGTH</PDBx:pdbx_diffrn_protocol>
         <PDBx:pdbx_monochromatic_or_laue_m_l>M</PDBx:pdbx_monochromatic_or_laue_m_l>
         <PDBx:pdbx_scattering_type>x-ray</PDBx:pdbx_scattering_type>
         <PDBx:wavelength_id>1</PDBx:wavelength_id>
      </PDBx:diffrn_radiation>
   </PDBx:diffrn_radiationCategory>
   <PDBx:diffrn_radiation_wavelengthCategory>
      <PDBx:diffrn_radiation_wavelength id="1">
         <PDBx:wavelength>0.9</PDBx:wavelength>
         <PDBx:wt>1.0</PDBx:wt>
      </PDBx:diffrn_radiation_wavelength>
   </PDBx:diffrn_radiation_wavelengthCategory>
   <PDBx:diffrn_sourceCategory>
      <PDBx:diffrn_source diffrn_id="1">
         <PDBx:pdbx_synchrotron_beamline>BL11-1</PDBx:pdbx_synchrotron_beamline>
         <PDBx:pdbx_synchrotron_site>SSRL</PDBx:pdbx_synchrotron_site>
         <PDBx:pdbx_wavelength_list>0.9</PDBx:pdbx_wavelength_list>
         <PDBx:source>SYNCHROTRON</PDBx:source>
         <PDBx:type>SSRL BEAMLINE BL11-1</PDBx:type>
      </PDBx:diffrn_source>
   </PDBx:diffrn_sourceCategory>
   <PDBx:entityCategory>
      <PDBx:entity id="1">
         <PDBx:formula_weight>29329.457</PDBx:formula_weight>
         <PDBx:pdbx_description>Estrogen receptor</PDBx:pdbx_description>
         <PDBx:pdbx_fragment>ligand-binding domain, UNP residues 301-559</PDBx:pdbx_fragment>
         <PDBx:pdbx_mutation>Y537S</PDBx:pdbx_mutation>
         <PDBx:pdbx_number_of_molecules>2</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>man</PDBx:src_method>
         <PDBx:type>polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="2">
         <PDBx:formula_weight>1579.866</PDBx:formula_weight>
         <PDBx:pdbx_description>Nuclear receptor-interacting peptide</PDBx:pdbx_description>
         <PDBx:pdbx_fragment>UNP residues 686-698</PDBx:pdbx_fragment>
         <PDBx:pdbx_number_of_molecules>2</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="3">
         <PDBx:formula_weight>454.467</PDBx:formula_weight>
         <PDBx:pdbx_description>3-fluorophenyl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>2</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>syn</PDBx:src_method>
         <PDBx:type>non-polymer</PDBx:type>
      </PDBx:entity>
      <PDBx:entity id="4">
         <PDBx:formula_weight>18.015</PDBx:formula_weight>
         <PDBx:pdbx_description>water</PDBx:pdbx_description>
         <PDBx:pdbx_number_of_molecules>231</PDBx:pdbx_number_of_molecules>
         <PDBx:src_method>nat</PDBx:src_method>
         <PDBx:type>water</PDBx:type>
      </PDBx:entity>
   </PDBx:entityCategory>
   <PDBx:entity_name_comCategory>
      <PDBx:entity_name_com entity_id="1">
         <PDBx:name>ER,ER-alpha,Estradiol receptor,Nuclear receptor subfamily 3 group A member 1</PDBx:name>
      </PDBx:entity_name_com>
      <PDBx:entity_name_com entity_id="2">
         <PDBx:name>NCoA-2,Class E basic helix-loop-helix protein 75,bHLHe75,Transcriptional intermediary factor 2,hTIF2</PDBx:name>
      </PDBx:entity_name_com>
   </PDBx:entity_name_comCategory>
   <PDBx:entity_polyCategory>
      <PDBx:entity_poly entity_id="1">
         <PDBx:nstd_linkage>no</PDBx:nstd_linkage>
         <PDBx:nstd_monomer>no</PDBx:nstd_monomer>
         <PDBx:pdbx_seq_one_letter_code>SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLE
CAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYT
FLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLL
LEMLDAHRLHAPTSRGGAS</PDBx:pdbx_seq_one_letter_code>
         <PDBx:pdbx_seq_one_letter_code_can>SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLE
CAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYT
FLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLSDLL
LEMLDAHRLHAPTSRGGAS</PDBx:pdbx_seq_one_letter_code_can>
         <PDBx:pdbx_strand_id>A,B</PDBx:pdbx_strand_id>
         <PDBx:type>polypeptide(L)</PDBx:type>
      </PDBx:entity_poly>
      <PDBx:entity_poly entity_id="2">
         <PDBx:nstd_linkage>no</PDBx:nstd_linkage>
         <PDBx:nstd_monomer>no</PDBx:nstd_monomer>
         <PDBx:pdbx_seq_one_letter_code>KHKILHRLLQDSS</PDBx:pdbx_seq_one_letter_code>
         <PDBx:pdbx_seq_one_letter_code_can>KHKILHRLLQDSS</PDBx:pdbx_seq_one_letter_code_can>
         <PDBx:pdbx_strand_id>C,D</PDBx:pdbx_strand_id>
         <PDBx:type>polypeptide(L)</PDBx:type>
      </PDBx:entity_poly>
   </PDBx:entity_polyCategory>
   <PDBx:entity_poly_seqCategory>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="1">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="2">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="3">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="4">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="5">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="6">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="7">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="8">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="9">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="10">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="11">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="12">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="13">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="14">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="15">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="16">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="17">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="18">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="19">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="20">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="21">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="22">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="23">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="24">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="25">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="26">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="27">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="28">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="29">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="30">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="31">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="32">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="33">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="34">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="35">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="36">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="37">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="38">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="39">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="40">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="41">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="42">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="43">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="44">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="45">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="46">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="47">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="48">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="49">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="50">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="51">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="52">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="53">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="54">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="55">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="56">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="57">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="58">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="59">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="60">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="61">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="62">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="63">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="64">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="65">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="66">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="67">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="68">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="69">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="70">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="71">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="72">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="73">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="74">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="75">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="76">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="77">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="78">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="79">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="80">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="81">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="82">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="83">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="84">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="85">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="86">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="87">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="88">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="89">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="90">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="91">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="92">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TRP" num="93">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="94">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="95">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="96">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="97">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="98">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="99">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="100">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="101">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="102">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="103">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="104">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="105">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="106">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="107">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="108">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="109">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="110">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="111">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="112">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="113">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="114">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="115">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="116">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="117">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="118">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="119">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="120">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="121">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="122">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="123">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="124">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="125">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="126">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="127">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="128">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="129">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="130">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="131">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="132">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="133">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="134">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="135">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="136">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="137">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="138">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="139">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="140">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="141">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="142">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="143">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="144">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="145">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="146">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="147">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="148">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="149">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="150">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="151">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="152">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="153">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="154">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="155">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="156">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="157">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="158">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="159">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="160">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PHE" num="161">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="162">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="163">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="164">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="165">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="166">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="167">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="168">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="169">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="170">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="171">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="172">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="173">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="174">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="175">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="176">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="177">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="178">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="179">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="180">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="181">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="182">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="183">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="184">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="185">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="186">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="187">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="188">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="189">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="190">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="191">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="192">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="193">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="194">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="195">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="196">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="197">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="198">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="199">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="200">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="201">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="202">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="203">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="204">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="205">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLN" num="206">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="207">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="208">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="209">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="210">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="211">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="212">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="213">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ILE" num="214">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="215">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="216">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="217">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="218">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="219">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="220">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="221">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="222">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="223">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="224">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="225">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="TYR" num="226">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="227">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="228">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="229">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="CYS" num="230">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LYS" num="231">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASN" num="232">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="233">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="VAL" num="234">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="235">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="236">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="237">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="238">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="239">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="240">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="241">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLU" num="242">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="MET" num="243">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="244">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ASP" num="245">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="246">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="247">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="248">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="LEU" num="249">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="HIS" num="250">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="251">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="PRO" num="252">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="THR" num="253">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="254">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ARG" num="255">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="256">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="GLY" num="257">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="ALA" num="258">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="1" mon_id="SER" num="259">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="LYS" num="1">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="HIS" num="2">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="LYS" num="3">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="ILE" num="4">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="LEU" num="5">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="HIS" num="6">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="ARG" num="7">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="LEU" num="8">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="LEU" num="9">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="GLN" num="10">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="ASP" num="11">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="SER" num="12">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
      <PDBx:entity_poly_seq entity_id="2" mon_id="SER" num="13">
         <PDBx:hetero>n</PDBx:hetero>
      </PDBx:entity_poly_seq>
   </PDBx:entity_poly_seqCategory>
   <PDBx:entity_src_genCategory>
      <PDBx:entity_src_gen entity_id="1" pdbx_src_id="1">
         <PDBx:gene_src_common_name>Human</PDBx:gene_src_common_name>
         <PDBx:pdbx_alt_source_flag>sample</PDBx:pdbx_alt_source_flag>
         <PDBx:pdbx_beg_seq_num>1</PDBx:pdbx_beg_seq_num>
         <PDBx:pdbx_end_seq_num>259</PDBx:pdbx_end_seq_num>
         <PDBx:pdbx_gene_src_gene>ESR1, ESR, NR3A1</PDBx:pdbx_gene_src_gene>
         <PDBx:pdbx_gene_src_ncbi_taxonomy_id>9606</PDBx:pdbx_gene_src_ncbi_taxonomy_id>
         <PDBx:pdbx_gene_src_scientific_name>Homo sapiens</PDBx:pdbx_gene_src_scientific_name>
         <PDBx:pdbx_host_org_ncbi_taxonomy_id>469008</PDBx:pdbx_host_org_ncbi_taxonomy_id>
         <PDBx:pdbx_host_org_scientific_name>Escherichia coli</PDBx:pdbx_host_org_scientific_name>
         <PDBx:pdbx_host_org_strain>BL21(DE3)</PDBx:pdbx_host_org_strain>
         <PDBx:pdbx_host_org_vector_type>plasmid</PDBx:pdbx_host_org_vector_type>
         <PDBx:pdbx_seq_type>Biological sequence</PDBx:pdbx_seq_type>
      </PDBx:entity_src_gen>
   </PDBx:entity_src_genCategory>
   <PDBx:entryCategory>
      <PDBx:entry id="4ZNS"></PDBx:entry>
   </PDBx:entryCategory>
   <PDBx:exptlCategory>
      <PDBx:exptl entry_id="4ZNS" method="X-RAY DIFFRACTION">
         <PDBx:crystals_number>1</PDBx:crystals_number>
      </PDBx:exptl>
   </PDBx:exptlCategory>
   <PDBx:exptl_crystalCategory>
      <PDBx:exptl_crystal id="1">
         <PDBx:density_Matthews>2.14</PDBx:density_Matthews>
         <PDBx:density_percent_sol>42.52</PDBx:density_percent_sol>
      </PDBx:exptl_crystal>
   </PDBx:exptl_crystalCategory>
   <PDBx:exptl_crystal_growCategory>
      <PDBx:exptl_crystal_grow crystal_id="1">
         <PDBx:method>VAPOR DIFFUSION, HANGING DROP</PDBx:method>
         <PDBx:pH>8.3</PDBx:pH>
         <PDBx:pdbx_details>15&#37; PEG 3350, 0.05M MgCl2, 0.067M NaCl, 0.1M Tris</PDBx:pdbx_details>
         <PDBx:temp>294</PDBx:temp>
      </PDBx:exptl_crystal_grow>
   </PDBx:exptl_crystal_growCategory>
   <PDBx:pdbx_audit_revision_detailsCategory>
      <PDBx:pdbx_audit_revision_details data_content_type="Structure model" ordinal="1" revision_ordinal="1">
         <PDBx:provider>repository</PDBx:provider>
         <PDBx:type>Initial release</PDBx:type>
      </PDBx:pdbx_audit_revision_details>
   </PDBx:pdbx_audit_revision_detailsCategory>
   <PDBx:pdbx_audit_revision_historyCategory>
      <PDBx:pdbx_audit_revision_history data_content_type="Structure model" ordinal="1">
         <PDBx:major_revision>1</PDBx:major_revision>
         <PDBx:minor_revision>0</PDBx:minor_revision>
         <PDBx:revision_date>2016-05-04</PDBx:revision_date>
      </PDBx:pdbx_audit_revision_history>
   </PDBx:pdbx_audit_revision_historyCategory>
   <PDBx:pdbx_database_relatedCategory>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="4PP6" db_name="PDB">
         <PDBx:details>4PP6 contains the same protein in complex with resveratrol</PDBx:details>
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="4ZN7" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="4ZN9" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="4ZNH" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="4ZNT" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="4ZNU" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="4ZNV" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
      <PDBx:pdbx_database_related content_type="unspecified" db_id="4ZNW" db_name="PDB">
         <PDBx:details xsi:nil="true" />
      </PDBx:pdbx_database_related>
   </PDBx:pdbx_database_relatedCategory>
   <PDBx:pdbx_database_statusCategory>
      <PDBx:pdbx_database_status entry_id="4ZNS">
         <PDBx:SG_entry>N</PDBx:SG_entry>
         <PDBx:deposit_site>RCSB</PDBx:deposit_site>
         <PDBx:pdb_format_compatible>Y</PDBx:pdb_format_compatible>
         <PDBx:process_site>RCSB</PDBx:process_site>
         <PDBx:recvd_initial_deposition_date>2015-05-05</PDBx:recvd_initial_deposition_date>
         <PDBx:status_code>REL</PDBx:status_code>
         <PDBx:status_code_sf>REL</PDBx:status_code_sf>
      </PDBx:pdbx_database_status>
   </PDBx:pdbx_database_statusCategory>
   <PDBx:pdbx_entity_nonpolyCategory>
      <PDBx:pdbx_entity_nonpoly entity_id="3">
         <PDBx:comp_id>OFB</PDBx:comp_id>
         <PDBx:name>3-fluorophenyl (1S,2R,4S)-5,6-bis(4-hydroxyphenyl)-7-oxabicyclo[2.2.1]hept-5-ene-2-sulfonate</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
      <PDBx:pdbx_entity_nonpoly entity_id="4">
         <PDBx:comp_id>HOH</PDBx:comp_id>
         <PDBx:name>water</PDBx:name>
      </PDBx:pdbx_entity_nonpoly>
   </PDBx:pdbx_entity_nonpolyCategory>
   <PDBx:pdbx_entity_src_synCategory>
      <PDBx:pdbx_entity_src_syn entity_id="2" pdbx_src_id="1">
         <PDBx:ncbi_taxonomy_id>9606</PDBx:ncbi_taxonomy_id>
         <PDBx:organism_common_name>Human</PDBx:organism_common_name>
         <PDBx:organism_scientific>Homo sapiens</PDBx:organism_scientific>
         <PDBx:pdbx_alt_source_flag>sample</PDBx:pdbx_alt_source_flag>
         <PDBx:pdbx_beg_seq_num>1</PDBx:pdbx_beg_seq_num>
         <PDBx:pdbx_end_seq_num>13</PDBx:pdbx_end_seq_num>
      </PDBx:pdbx_entity_src_syn>
   </PDBx:pdbx_entity_src_synCategory>
   <PDBx:pdbx_nonpoly_schemeCategory>
      <PDBx:pdbx_nonpoly_scheme asym_id="E" ndb_seq_num="1">
         <PDBx:auth_mon_id>OFB</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>OFB</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>OFB</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>601</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="F" ndb_seq_num="1">
         <PDBx:auth_mon_id>OFB</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:mon_id>OFB</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>OFB</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>601</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>161</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>701</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>203</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>702</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>219</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>703</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="4">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>120</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>704</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="5">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>164</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>705</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="6">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>150</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>706</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="7">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>231</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>707</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="8">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>69</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>708</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="9">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>88</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>709</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="10">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>72</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>710</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="11">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>210</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>711</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="12">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>42</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>712</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="13">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>144</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>713</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="14">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>127</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>714</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="15">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>94</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>715</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="16">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>108</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>716</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="17">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>73</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>717</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="18">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>51</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>718</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="19">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>78</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>719</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="20">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>107</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>720</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="21">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>147</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>721</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="22">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>25</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>722</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="23">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>103</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>723</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="24">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>100</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>724</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="25">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>44</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>725</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="26">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>56</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>726</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="27">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>13</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>727</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="28">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>35</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>728</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="29">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>204</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>729</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="30">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>54</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>730</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="31">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>52</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>731</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="32">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>186</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>732</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="33">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>15</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>733</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="34">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>67</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>734</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="35">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>82</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>735</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="36">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>179</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>736</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="37">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>71</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>737</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="38">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>17</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>738</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="39">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>123</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>739</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="40">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>64</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>740</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="41">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>6</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>741</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="42">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>36</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>742</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="43">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>14</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>743</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="44">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>220</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>744</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="45">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>80</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>745</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="46">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>184</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>746</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="47">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>170</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>747</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="48">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>10</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>748</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="49">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>84</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>749</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="50">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>191</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>750</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="51">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>26</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>751</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="52">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>76</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>752</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="53">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>176</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>753</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="54">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>201</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>754</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="55">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>75</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>755</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="56">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>60</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>756</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="57">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>112</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>757</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="58">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>53</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>758</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="59">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>138</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>759</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="60">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>213</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>760</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="61">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>63</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>761</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="62">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>162</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>762</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="63">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>200</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>763</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="64">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>193</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>764</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="65">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>22</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>765</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="66">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>111</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>766</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="67">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>9</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>767</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="68">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>21</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>768</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="69">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>217</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>769</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="70">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>209</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>770</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="71">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>85</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>771</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="72">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>11</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>772</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="73">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>106</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>773</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="74">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>132</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>774</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="75">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>92</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>775</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="76">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>74</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>776</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="77">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>58</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>777</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="78">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>39</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>778</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="79">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>182</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>779</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="80">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>101</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>780</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="81">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>199</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>781</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="82">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>66</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>782</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="83">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>212</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>783</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="84">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>119</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>784</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="85">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>156</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>785</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="86">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>98</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>786</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="87">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>163</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>787</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="88">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>62</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>788</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="89">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>139</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>789</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="90">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>166</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>790</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="91">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>1</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>791</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="92">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>117</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>792</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="93">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>222</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>793</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="94">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>229</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>794</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="95">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>221</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>795</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="96">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>177</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>796</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="97">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>197</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>797</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="98">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>165</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>798</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="99">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>48</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>799</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="100">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>168</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>800</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="101">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>202</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>801</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="102">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>141</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>802</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="103">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>207</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>803</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="104">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>187</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>804</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="105">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>183</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>805</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="106">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>172</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>806</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="107">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>211</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>807</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="108">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>226</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>808</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="109">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>28</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>809</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="G" ndb_seq_num="110">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>224</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>810</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>3</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>701</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>218</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>702</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>110</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>703</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="4">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>83</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>704</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="5">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>50</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>705</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="6">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>136</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>706</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="7">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>142</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>707</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="8">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>46</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>708</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="9">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>93</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>709</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="10">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>154</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>710</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="11">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>33</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>711</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="12">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>215</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>712</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="13">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>148</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>713</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="14">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>124</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>714</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="15">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>90</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>715</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="16">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>57</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>716</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="17">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>185</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>717</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="18">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>16</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>718</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="19">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>158</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>719</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="20">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>195</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>720</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="21">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>81</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>721</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="22">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>20</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>722</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="23">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>99</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>723</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="24">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>146</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>724</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="25">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>45</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>725</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="26">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>113</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>726</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="27">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>175</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>727</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="28">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>32</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>728</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="29">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>5</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>729</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="30">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>206</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>730</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="31">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>61</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>731</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="32">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>118</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>732</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="33">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>19</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>733</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="34">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>18</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>734</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="35">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>95</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>735</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="36">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>173</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>736</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="37">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>174</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>737</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="38">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>41</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>738</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="39">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>105</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>739</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="40">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>79</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>740</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="41">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>196</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>741</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="42">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>198</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>742</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="43">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>2</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>743</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="44">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>102</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>744</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="45">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>181</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>745</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="46">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>24</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>746</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="47">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>31</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>747</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="48">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>70</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>748</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="49">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>131</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>749</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="50">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>43</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>750</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="51">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>4</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>751</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="52">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>227</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>752</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="53">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>189</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>753</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="54">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>122</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>754</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="55">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>29</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>755</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="56">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>8</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>756</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="57">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>87</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>757</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="58">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>153</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>758</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="59">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>188</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>759</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="60">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>114</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>760</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="61">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>149</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>761</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="62">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>40</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>762</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="63">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>178</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>763</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="64">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>12</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>764</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="65">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>37</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>765</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="66">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>151</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>766</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="67">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>145</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>767</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="68">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>30</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>768</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="69">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>77</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>769</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="70">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>128</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>770</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="71">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>96</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>771</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="72">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>115</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>772</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="73">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>137</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>773</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="74">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>129</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>774</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="75">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>38</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>775</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="76">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>135</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>776</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="77">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>140</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>777</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="78">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>167</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>778</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="79">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>121</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>779</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="80">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>59</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>780</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="81">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>27</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>781</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="82">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>65</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>782</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="83">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>55</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>783</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="84">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>169</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>784</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="85">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>126</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>785</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="86">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>91</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>786</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="87">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>133</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>787</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="88">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>230</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>788</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="89">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>180</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>789</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="90">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>134</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>790</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="91">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>130</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>791</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="92">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>214</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>792</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="93">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>223</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>793</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="94">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>194</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>794</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="95">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>216</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>795</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="96">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>225</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>796</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="97">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>205</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>797</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="98">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>192</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>798</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="99">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>47</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>799</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="100">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>171</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>800</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="101">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>155</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>801</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="102">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>143</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>802</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="103">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>34</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>803</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="104">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>116</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>804</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="105">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>190</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>805</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="106">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>125</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>806</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="107">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>89</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>807</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="108">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>104</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>808</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="109">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>152</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>809</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="110">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>157</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>810</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="111">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>68</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>811</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="112">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>97</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>812</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="113">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>7</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>813</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="114">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>23</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>814</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="H" ndb_seq_num="115">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>208</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>815</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="I" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>49</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>701</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="I" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>109</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>702</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="I" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>86</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>703</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="J" ndb_seq_num="1">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>228</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>701</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="J" ndb_seq_num="2">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>159</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>702</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
      <PDBx:pdbx_nonpoly_scheme asym_id="J" ndb_seq_num="3">
         <PDBx:auth_mon_id>HOH</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>160</PDBx:auth_seq_num>
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:mon_id>HOH</PDBx:mon_id>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HOH</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>703</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_nonpoly_scheme>
   </PDBx:pdbx_nonpoly_schemeCategory>
   <PDBx:pdbx_poly_seq_schemeCategory>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="1">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>301</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="2">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>302</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="3">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>303</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="4">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>304</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="5">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>305</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="6">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>306</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>306</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="7">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>307</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>307</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="8">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>308</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>308</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="9">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>309</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>309</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="10">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>310</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>310</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="11">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>311</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>311</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="12">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>312</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>312</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="13">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>313</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>313</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="14">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>314</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>14</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>314</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="15">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>315</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>15</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>315</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="16">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>316</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>16</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>316</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="17">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>317</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>17</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>317</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="18">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>318</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>18</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>318</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="19">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>319</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>19</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>319</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="20">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>320</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>20</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>320</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="21">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>321</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>21</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>321</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="22">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>322</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>22</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>322</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="23">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>323</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>23</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>323</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="24">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>324</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>24</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>324</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="25">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>325</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>25</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>325</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="26">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>326</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>26</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>326</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="27">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>327</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>27</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>327</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="28">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>328</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>28</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>328</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="29">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>329</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>29</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>329</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="30">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>330</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>30</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>330</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="31">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>331</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>31</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>331</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="32">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>32</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>332</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="33">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>33</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>333</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="34">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>34</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>334</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="35">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>35</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>335</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="36">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>336</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>36</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>336</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="37">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>337</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>37</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>337</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="38">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>338</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>38</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>338</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="39">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>339</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>39</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>339</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="40">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>340</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>40</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>340</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="41">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>341</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>41</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>341</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="42">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>342</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>42</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>342</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="43">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>343</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>43</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>343</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="44">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>344</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>44</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>344</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="45">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>345</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>45</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>345</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="46">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>346</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>46</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>346</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="47">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>347</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>47</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>347</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="48">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>348</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>48</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>348</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="49">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>349</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>49</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>349</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="50">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>350</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>50</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>350</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="51">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>351</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>51</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>351</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="52">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>352</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>52</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>352</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="53">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>353</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>53</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>353</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="54">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>354</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>54</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>354</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="55">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>355</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>55</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>355</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="56">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>356</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>56</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>356</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="57">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>357</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>57</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>357</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="58">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>358</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>58</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>358</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="59">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>359</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>59</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>359</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="60">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>360</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>60</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>360</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="61">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>361</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>61</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>361</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="62">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>362</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>62</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>362</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="63">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>363</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>63</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>363</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="64">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>364</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>64</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>364</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="65">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>365</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>65</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>365</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="66">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>366</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>66</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>366</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="67">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>367</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>67</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>367</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="68">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>368</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>68</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>368</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="69">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>369</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>69</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>369</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="70">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>370</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>70</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>370</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="71">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>371</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>71</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>371</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="72">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>372</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>72</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>372</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="73">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>373</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>73</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>373</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="74">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>374</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>74</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>374</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="75">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>375</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>75</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>375</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="76">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>376</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>76</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>376</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="77">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>377</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>77</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>377</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="78">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>378</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>78</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>378</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="79">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>379</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>79</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>379</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="80">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>380</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>80</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>380</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="81">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>381</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>81</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>381</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="82">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>382</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>82</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>382</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="83">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>383</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>83</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>383</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="84">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>384</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>84</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>384</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="85">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>385</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>85</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>385</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="86">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>386</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>86</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>386</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="87">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>387</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>87</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>387</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="88">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>388</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>88</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>388</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="89">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>389</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>89</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>389</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="90">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>390</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>90</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>390</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="91">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>391</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>91</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>391</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="92">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>392</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>92</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>392</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TRP" seq_id="93">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>393</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>93</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>393</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="94">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>394</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>94</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>394</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="95">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>395</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>95</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>395</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="96">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>396</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>96</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>396</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="97">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>397</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>97</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>397</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="98">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>398</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>98</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>398</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="99">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>399</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>99</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>399</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="100">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>400</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>100</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>400</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="101">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>401</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>101</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>401</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="102">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>402</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>102</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>402</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="103">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>403</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>103</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>403</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="104">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>404</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>104</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>404</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="105">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>405</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>105</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>405</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="106">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>406</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>106</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>406</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="107">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>407</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>107</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>407</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="108">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>408</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>108</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>408</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="109">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>409</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>109</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>409</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="110">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>410</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>110</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>410</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="111">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>411</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>111</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>411</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="112">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>412</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>112</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>412</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="113">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>413</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>113</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>413</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="114">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>414</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>114</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>414</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="115">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>415</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>115</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>415</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="116">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>416</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>116</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>416</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="117">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>417</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>117</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>417</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="118">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>418</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>118</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>418</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="119">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>419</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>119</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>419</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="120">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>420</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>120</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>420</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="121">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>421</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>121</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>421</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="122">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>422</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>122</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>422</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="123">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>423</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>123</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>423</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="124">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>424</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>124</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>424</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="125">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>425</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>125</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>425</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="126">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>426</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>126</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>426</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="127">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>427</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>127</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>427</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="128">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>428</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>128</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>428</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="129">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>429</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>129</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>429</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="130">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>430</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>130</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>430</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="131">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>431</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>131</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>431</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="132">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>432</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>132</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>432</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="133">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>433</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>133</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>433</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="134">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>434</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>134</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>434</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="135">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>435</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>135</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>435</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="136">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>436</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>136</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>436</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="137">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>437</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>137</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>437</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="138">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>438</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>138</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>438</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="139">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>439</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>139</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>439</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="140">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>440</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>140</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>440</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="141">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>441</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>141</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>441</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="142">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>442</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>142</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>442</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="143">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>443</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>143</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>443</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="144">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>444</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>144</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>444</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="145">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>445</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>145</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>445</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="146">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>446</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>146</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>446</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="147">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>447</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>147</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>447</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="148">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>448</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>148</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>448</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="149">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>449</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>149</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>449</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="150">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>450</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>150</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>450</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="151">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>451</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>151</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>451</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="152">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>452</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>152</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>452</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="153">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>453</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>153</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>453</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="154">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>454</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>154</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>454</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="155">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>455</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>155</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>455</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="156">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>456</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>156</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>456</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="157">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>457</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>157</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>457</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="158">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>458</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>158</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>458</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="159">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>459</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>159</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>459</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="160">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>460</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>160</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>460</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PHE" seq_id="161">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>461</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>161</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>461</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="162">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>462</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>162</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>462</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="163">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>163</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>463</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="164">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>164</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>464</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="165">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>165</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>465</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="166">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>166</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>466</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="167">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>167</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>467</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="168">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>168</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>468</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="169">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>169</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>469</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="170">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>170</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>470</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="171">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>171</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>471</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="172">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>472</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>172</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>472</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="173">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>473</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>173</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>473</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="174">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>474</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>174</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>474</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="175">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>475</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>175</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>475</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="176">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>476</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>176</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>476</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="177">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>477</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>177</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>477</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="178">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>478</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>178</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>478</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="179">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>479</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>179</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>479</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="180">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>480</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>180</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>480</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="181">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>481</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>181</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>481</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="182">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>482</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>182</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>482</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="183">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>483</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>183</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>483</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="184">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>484</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>184</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>484</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="185">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>485</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>185</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>485</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="186">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>486</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>186</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>486</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="187">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>487</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>187</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>487</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="188">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>488</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>188</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>488</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="189">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>489</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>189</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>489</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="190">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>490</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>190</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>490</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="191">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>491</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>191</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>491</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="192">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>492</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>192</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>492</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="193">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>493</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>193</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>493</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="194">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>494</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>194</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>494</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="195">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>495</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>195</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>495</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="196">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>496</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>196</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>496</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="197">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>497</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>197</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>497</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="198">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>498</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>198</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>498</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="199">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>499</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>199</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>499</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="200">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>500</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>200</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>500</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="201">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>501</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>201</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>501</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="202">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>502</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>202</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>502</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="203">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>503</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>203</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>503</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="204">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>504</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>204</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>504</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="205">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>505</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>205</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>505</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLN" seq_id="206">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>506</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>206</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>506</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="207">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>507</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>207</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>507</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="208">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>508</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>208</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>508</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="209">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>509</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>209</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>509</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="210">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>510</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>210</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>510</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="211">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>511</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>211</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>511</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="212">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>512</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>212</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>512</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="213">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>513</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>213</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>513</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ILE" seq_id="214">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>514</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>214</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>514</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="215">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>515</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>215</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>515</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="216">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>516</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>216</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>516</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="217">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>517</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>217</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>517</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="218">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>518</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>218</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>518</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="219">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>519</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>219</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>519</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="220">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>520</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>220</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>520</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="221">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>521</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>221</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>521</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="222">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>522</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>222</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>522</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="223">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>523</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>223</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>523</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="224">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>524</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>224</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>524</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="225">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>525</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>225</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>525</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="TYR" seq_id="226">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>526</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>226</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>526</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="227">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>527</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>227</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>527</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="228">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>528</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>228</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>528</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="229">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>529</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>229</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>529</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="CYS" seq_id="230">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>230</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>530</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LYS" seq_id="231">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>231</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>531</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASN" seq_id="232">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>532</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>232</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>532</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="233">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>533</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>233</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>533</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="VAL" seq_id="234">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>534</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>234</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>534</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="235">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>535</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>235</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>535</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="236">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>536</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>236</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>536</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="237">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>537</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>237</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>537</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="238">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>538</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>238</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>538</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="239">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>539</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>239</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>539</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="240">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>540</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>240</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>540</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="241">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>541</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>241</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>541</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLU" seq_id="242">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>542</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>242</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>542</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="MET" seq_id="243">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>543</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>243</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>543</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="244">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>544</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>244</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>544</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ASP" seq_id="245">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>545</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>245</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>545</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="246">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>546</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>246</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>546</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="247">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>547</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>247</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>547</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="248">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>548</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>248</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>548</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="LEU" seq_id="249">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>549</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>249</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>549</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="HIS" seq_id="250">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>550</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>250</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>550</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="251">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>551</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>251</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>551</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="PRO" seq_id="252">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>252</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>552</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="THR" seq_id="253">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>253</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>553</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="254">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>254</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>554</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ARG" seq_id="255">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>255</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>555</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="256">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>256</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>556</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="GLY" seq_id="257">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>257</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>557</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="ALA" seq_id="258">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>258</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>558</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="A" entity_id="1" mon_id="SER" seq_id="259">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>259</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>559</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>A</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="1">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>301</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="2">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>302</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="3">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>303</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASN" seq_id="4">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>304</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="5">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>305</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="6">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>306</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>306</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="7">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>307</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>307</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="8">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>308</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>308</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="9">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>309</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>309</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="10">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>310</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>310</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="THR" seq_id="11">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>311</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>311</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="12">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>312</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>312</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="13">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>313</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>313</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLN" seq_id="14">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>314</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>14</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>314</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="15">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>315</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>15</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>315</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="16">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>316</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>16</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>316</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="17">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>317</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>17</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>317</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="18">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>318</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>18</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>318</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="19">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>319</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>19</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>319</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="20">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>320</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>20</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>320</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="21">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>321</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>21</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>321</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="22">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>322</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>22</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>322</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="23">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>323</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>23</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>323</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PRO" seq_id="24">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>324</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>24</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>324</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PRO" seq_id="25">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>325</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>25</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>325</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ILE" seq_id="26">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>326</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>26</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>326</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="27">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>327</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>27</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>327</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="TYR" seq_id="28">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>328</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>28</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>328</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="29">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>329</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>29</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>329</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="30">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>330</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>30</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>330</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="TYR" seq_id="31">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>331</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>31</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>331</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="32">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>332</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>32</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>332</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PRO" seq_id="33">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>333</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>33</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>333</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="THR" seq_id="34">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>334</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>34</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>334</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ARG" seq_id="35">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>335</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>35</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>335</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PRO" seq_id="36">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>336</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>36</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>336</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PHE" seq_id="37">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>337</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>37</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>337</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="38">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>338</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>38</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>338</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="39">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>339</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>39</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>339</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="40">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>340</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>40</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>340</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="41">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>341</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>41</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>341</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="42">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>342</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>42</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>342</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="43">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>343</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>43</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>343</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="44">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>344</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>44</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>344</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="45">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>345</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>45</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>345</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="46">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>346</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>46</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>346</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="THR" seq_id="47">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>347</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>47</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>347</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASN" seq_id="48">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>348</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>48</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>348</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="49">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>349</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>49</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>349</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="50">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>350</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>50</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>350</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="51">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>351</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>51</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>351</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ARG" seq_id="52">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>352</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>52</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>352</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="53">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>353</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>53</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>353</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="54">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>354</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>54</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>354</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="55">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>355</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>55</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>355</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="56">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>356</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>56</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>356</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="57">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>357</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>57</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>357</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ILE" seq_id="58">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>358</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>58</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>358</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASN" seq_id="59">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>359</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>59</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>359</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="TRP" seq_id="60">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>360</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>60</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>360</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="61">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>361</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>61</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>361</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="62">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>362</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>62</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>362</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ARG" seq_id="63">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>363</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>63</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>363</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="64">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>364</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>64</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>364</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PRO" seq_id="65">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>365</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>65</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>365</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="66">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>366</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>66</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>366</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PHE" seq_id="67">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>367</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>67</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>367</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="68">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>368</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>68</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>368</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="69">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>369</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>69</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>369</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="70">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>370</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>70</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>370</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="THR" seq_id="71">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>371</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>71</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>371</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="72">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>372</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>72</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>372</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="73">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>373</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>73</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>373</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="74">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>374</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>74</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>374</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLN" seq_id="75">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>375</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>75</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>375</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="76">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>376</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>76</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>376</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="77">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>377</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>77</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>377</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="78">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>378</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>78</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>378</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="79">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>379</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>79</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>379</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="80">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>380</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>80</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>380</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="CYS" seq_id="81">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>381</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>81</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>381</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="82">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>382</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>82</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>382</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="TRP" seq_id="83">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>383</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>83</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>383</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="84">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>384</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>84</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>384</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="85">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>385</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>85</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>385</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ILE" seq_id="86">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>386</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>86</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>386</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="87">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>387</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>87</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>387</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="88">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>388</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>88</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>388</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ILE" seq_id="89">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>389</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>89</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>389</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="90">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>390</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>90</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>390</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="91">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>391</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>91</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>391</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="92">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>392</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>92</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>392</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="TRP" seq_id="93">
         <PDBx:auth_mon_id>TRP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>393</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>93</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TRP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>393</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ARG" seq_id="94">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>394</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>94</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>394</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="95">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>395</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>95</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>395</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="96">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>396</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>96</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>396</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="97">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>397</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>97</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>397</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="98">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>398</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>98</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>398</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PRO" seq_id="99">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>399</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>99</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>399</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="100">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>400</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>100</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>400</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="101">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>401</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>101</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>401</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="102">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>402</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>102</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>402</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="103">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>403</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>103</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>403</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PHE" seq_id="104">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>404</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>104</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>404</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="105">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>405</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>105</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>405</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PRO" seq_id="106">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>406</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>106</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>406</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASN" seq_id="107">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>407</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>107</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>407</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="108">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>408</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>108</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>408</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="109">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>409</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>109</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>409</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="110">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>410</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>110</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>410</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="111">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>411</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>111</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>411</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ARG" seq_id="112">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>412</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>112</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>412</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASN" seq_id="113">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>413</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>113</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>413</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLN" seq_id="114">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>414</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>114</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>414</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="115">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>415</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>115</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>415</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="116">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>416</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>116</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>416</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="CYS" seq_id="117">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>417</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>117</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>417</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="118">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>418</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>118</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>418</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="119">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>419</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>119</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>419</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="120">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>420</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>120</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>420</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="121">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>421</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>121</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>421</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="122">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>422</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>122</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>422</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="123">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>423</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>123</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>423</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ILE" seq_id="124">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>424</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>124</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>424</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PHE" seq_id="125">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>425</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>125</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>425</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="126">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>426</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>126</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>426</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="127">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>427</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>127</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>427</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="128">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>428</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>128</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>428</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="129">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>429</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>129</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>429</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="130">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>430</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>130</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>430</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="THR" seq_id="131">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>431</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>131</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>431</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="132">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>432</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>132</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>432</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="133">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>433</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>133</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>433</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ARG" seq_id="134">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>434</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>134</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>434</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PHE" seq_id="135">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>435</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>135</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>435</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ARG" seq_id="136">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>436</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>136</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>436</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="137">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>437</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>137</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>437</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="138">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>438</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>138</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>438</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASN" seq_id="139">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>439</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>139</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>439</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="140">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>440</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>140</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>440</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLN" seq_id="141">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>441</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>141</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>441</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="142">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>442</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>142</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>442</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="143">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>443</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>143</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>443</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="144">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>444</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>144</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>444</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PHE" seq_id="145">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>445</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>145</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>445</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="146">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>446</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>146</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>446</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="CYS" seq_id="147">
         <PDBx:auth_mon_id>CYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>447</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>147</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>CYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>447</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="148">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>448</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>148</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>448</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="149">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>449</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>149</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>449</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="150">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>450</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>150</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>450</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ILE" seq_id="151">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>451</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>151</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>451</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ILE" seq_id="152">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>452</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>152</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>452</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="153">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>453</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>153</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>453</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="154">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>454</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>154</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>454</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASN" seq_id="155">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>455</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>155</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>455</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="156">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>456</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>156</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>456</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="157">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>457</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>157</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>457</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="158">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>458</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>158</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>458</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="TYR" seq_id="159">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>459</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>159</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>459</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="THR" seq_id="160">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>460</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>160</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>460</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PHE" seq_id="161">
         <PDBx:auth_mon_id>PHE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>461</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>161</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PHE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>461</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="162">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>162</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>462</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="163">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>163</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>463</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="164">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>164</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>464</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="THR" seq_id="165">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>165</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>465</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="166">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>166</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>466</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="167">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>467</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>167</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>467</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="168">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>468</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>168</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>468</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="169">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>469</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>169</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>469</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="170">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>470</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>170</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>470</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="171">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>471</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>171</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>471</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="172">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>472</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>172</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>472</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="173">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>473</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>173</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>473</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="174">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>474</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>174</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>474</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ILE" seq_id="175">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>475</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>175</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>475</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="176">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>476</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>176</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>476</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ARG" seq_id="177">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>477</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>177</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>477</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="178">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>478</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>178</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>478</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="179">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>479</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>179</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>479</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="180">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>480</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>180</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>480</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="181">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>481</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>181</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>481</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ILE" seq_id="182">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>482</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>182</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>482</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="THR" seq_id="183">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>483</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>183</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>483</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="184">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>484</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>184</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>484</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="THR" seq_id="185">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>485</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>185</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>485</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="186">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>486</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>186</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>486</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ILE" seq_id="187">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>487</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>187</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>487</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="188">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>488</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>188</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>488</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="189">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>489</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>189</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>489</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="190">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>490</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>190</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>490</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="191">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>491</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>191</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>491</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="192">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>492</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>192</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>492</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="193">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>493</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>193</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>493</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="194">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>494</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>194</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>494</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="195">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>495</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>195</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>495</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="THR" seq_id="196">
         <PDBx:auth_mon_id>THR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>496</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>196</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>THR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>496</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="197">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>497</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>197</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>497</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLN" seq_id="198">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>498</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>198</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>498</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLN" seq_id="199">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>499</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>199</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>499</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLN" seq_id="200">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>500</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>200</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>500</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="201">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>501</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>201</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>501</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLN" seq_id="202">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>502</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>202</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>502</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ARG" seq_id="203">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>503</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>203</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>503</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="204">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>504</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>204</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>504</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="205">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>505</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>205</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>505</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLN" seq_id="206">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>506</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>206</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>506</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="207">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>507</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>207</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>507</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="208">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>508</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>208</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>508</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="209">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>509</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>209</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>509</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ILE" seq_id="210">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>510</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>210</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>510</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="211">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>511</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>211</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>511</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="212">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>512</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>212</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>512</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="213">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>513</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>213</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>513</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ILE" seq_id="214">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>514</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>214</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>514</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ARG" seq_id="215">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>515</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>215</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>515</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="216">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>516</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>216</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>516</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="217">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>517</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>217</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>517</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="218">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>518</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>218</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>518</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASN" seq_id="219">
         <PDBx:auth_mon_id>ASN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>519</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>219</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>519</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="220">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>520</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>220</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>520</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="221">
         <PDBx:auth_mon_id>GLY</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>521</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>221</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLY</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>521</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="222">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>522</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>222</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>522</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="223">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>523</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>223</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>523</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="224">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>524</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>224</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>524</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="225">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>525</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>225</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>525</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="TYR" seq_id="226">
         <PDBx:auth_mon_id>TYR</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>526</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>226</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>TYR</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>526</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="227">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>527</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>227</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>527</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="228">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>528</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>228</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>528</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="229">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>529</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>229</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>529</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="CYS" seq_id="230">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>230</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>530</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LYS" seq_id="231">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>231</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>531</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASN" seq_id="232">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>232</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>532</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="233">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>533</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>233</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>533</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="VAL" seq_id="234">
         <PDBx:auth_mon_id>VAL</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>534</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>234</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>VAL</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>534</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PRO" seq_id="235">
         <PDBx:auth_mon_id>PRO</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>535</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>235</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>PRO</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>535</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="236">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>536</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>236</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>536</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="237">
         <PDBx:auth_mon_id>SER</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>537</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>237</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>SER</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>537</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="238">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>538</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>238</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>538</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="239">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>539</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>239</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>539</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="240">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>540</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>240</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>540</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="241">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>541</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>241</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>541</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLU" seq_id="242">
         <PDBx:auth_mon_id>GLU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>542</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>242</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>542</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="MET" seq_id="243">
         <PDBx:auth_mon_id>MET</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>543</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>243</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>MET</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>543</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="244">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>544</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>244</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>544</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ASP" seq_id="245">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>545</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>245</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>545</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="246">
         <PDBx:auth_mon_id>ALA</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>546</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>246</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ALA</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>546</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="247">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>547</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>247</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>547</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ARG" seq_id="248">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>548</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>248</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>548</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="LEU" seq_id="249">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>549</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>249</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>549</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="HIS" seq_id="250">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>250</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>550</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="251">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>251</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>551</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="PRO" seq_id="252">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>252</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>552</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="THR" seq_id="253">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>253</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>553</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="254">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>254</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>554</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ARG" seq_id="255">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>255</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>555</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="256">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>256</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>556</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="GLY" seq_id="257">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>257</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>557</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="ALA" seq_id="258">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>258</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>558</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="B" entity_id="1" mon_id="SER" seq_id="259">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>259</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>559</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>B</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="LYS" seq_id="1">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>686</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="HIS" seq_id="2">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>687</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>687</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="LYS" seq_id="3">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>688</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>688</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="ILE" seq_id="4">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>689</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>689</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="LEU" seq_id="5">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>690</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>690</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="HIS" seq_id="6">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>691</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>691</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="ARG" seq_id="7">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>692</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>692</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="LEU" seq_id="8">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>693</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>693</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="LEU" seq_id="9">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>694</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>694</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="GLN" seq_id="10">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>695</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>695</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="ASP" seq_id="11">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>696</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>696</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="SER" seq_id="12">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>697</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="C" entity_id="2" mon_id="SER" seq_id="13">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>698</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>C</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="LYS" seq_id="1">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>1</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>686</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="HIS" seq_id="2">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>2</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>687</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="LYS" seq_id="3">
         <PDBx:auth_mon_id>LYS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>688</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>3</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LYS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>688</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="ILE" seq_id="4">
         <PDBx:auth_mon_id>ILE</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>689</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>4</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ILE</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>689</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="LEU" seq_id="5">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>690</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>5</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>690</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="HIS" seq_id="6">
         <PDBx:auth_mon_id>HIS</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>691</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>6</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>HIS</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>691</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="ARG" seq_id="7">
         <PDBx:auth_mon_id>ARG</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>692</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>7</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ARG</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>692</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="LEU" seq_id="8">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>693</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>8</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>693</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="LEU" seq_id="9">
         <PDBx:auth_mon_id>LEU</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>694</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>9</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>LEU</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>694</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="GLN" seq_id="10">
         <PDBx:auth_mon_id>GLN</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>695</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>10</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>GLN</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>695</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="ASP" seq_id="11">
         <PDBx:auth_mon_id>ASP</PDBx:auth_mon_id>
         <PDBx:auth_seq_num>696</PDBx:auth_seq_num>
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>11</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_mon_id>ASP</PDBx:pdb_mon_id>
         <PDBx:pdb_seq_num>696</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="SER" seq_id="12">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>12</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>697</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
      <PDBx:pdbx_poly_seq_scheme asym_id="D" entity_id="2" mon_id="SER" seq_id="13">
         <PDBx:hetero>n</PDBx:hetero>
         <PDBx:ndb_seq_num>13</PDBx:ndb_seq_num>
         <PDBx:pdb_ins_code xsi:nil="true" />
         <PDBx:pdb_seq_num>698</PDBx:pdb_seq_num>
         <PDBx:pdb_strand_id>D</PDBx:pdb_strand_id>
      </PDBx:pdbx_poly_seq_scheme>
   </PDBx:pdbx_poly_seq_schemeCategory>
   <PDBx:pdbx_struct_assemblyCategory>
      <PDBx:pdbx_struct_assembly id="1">
         <PDBx:details>author_and_software_defined_assembly</PDBx:details>
         <PDBx:method_details>PISA</PDBx:method_details>
         <PDBx:oligomeric_count>4</PDBx:oligomeric_count>
         <PDBx:oligomeric_details>tetrameric</PDBx:oligomeric_details>
      </PDBx:pdbx_struct_assembly>
   </PDBx:pdbx_struct_assemblyCategory>
   <PDBx:pdbx_struct_assembly_genCategory>
      <PDBx:pdbx_struct_assembly_gen assembly_id="1" asym_id_list="A,B,C,D,E,F,G,H,I,J" oper_expression="1"></PDBx:pdbx_struct_assembly_gen>
   </PDBx:pdbx_struct_assembly_genCategory>
   <PDBx:pdbx_struct_assembly_propCategory>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="ABSA (A^2)">
         <PDBx:value>5580</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="MORE">
         <PDBx:value>-32</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
      <PDBx:pdbx_struct_assembly_prop biol_id="1" type="SSA (A^2)">
         <PDBx:value>18830</PDBx:value>
      </PDBx:pdbx_struct_assembly_prop>
   </PDBx:pdbx_struct_assembly_propCategory>
   <PDBx:pdbx_struct_oper_listCategory>
      <PDBx:pdbx_struct_oper_list id="1">
         <PDBx:matrix11>1.0000000000</PDBx:matrix11>
         <PDBx:matrix12>0.0000000000</PDBx:matrix12>
         <PDBx:matrix13>0.0000000000</PDBx:matrix13>
         <PDBx:matrix21>0.0000000000</PDBx:matrix21>
         <PDBx:matrix22>1.0000000000</PDBx:matrix22>
         <PDBx:matrix23>0.0000000000</PDBx:matrix23>
         <PDBx:matrix31>0.0000000000</PDBx:matrix31>
         <PDBx:matrix32>0.0000000000</PDBx:matrix32>
         <PDBx:matrix33>1.0000000000</PDBx:matrix33>
         <PDBx:name>1_555</PDBx:name>
         <PDBx:symmetry_operation>x,y,z</PDBx:symmetry_operation>
         <PDBx:type>identity operation</PDBx:type>
         <PDBx:vector1>0.0000000000</PDBx:vector1>
         <PDBx:vector2>0.0000000000</PDBx:vector2>
         <PDBx:vector3>0.0000000000</PDBx:vector3>
      </PDBx:pdbx_struct_oper_list>
   </PDBx:pdbx_struct_oper_listCategory>
   <PDBx:pdbx_struct_sheet_hbondCategory>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA1">
         <PDBx:range_1_auth_asym_id>A</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>LEU</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>402</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>A</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>LEU</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>102</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>A</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LEU</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>410</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>A</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LEU</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>110</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
      <PDBx:pdbx_struct_sheet_hbond range_id_1="1" range_id_2="2" sheet_id="AA2">
         <PDBx:range_1_auth_asym_id>B</PDBx:range_1_auth_asym_id>
         <PDBx:range_1_auth_atom_id>N</PDBx:range_1_auth_atom_id>
         <PDBx:range_1_auth_comp_id>LEU</PDBx:range_1_auth_comp_id>
         <PDBx:range_1_auth_seq_id>402</PDBx:range_1_auth_seq_id>
         <PDBx:range_1_label_asym_id>B</PDBx:range_1_label_asym_id>
         <PDBx:range_1_label_atom_id>N</PDBx:range_1_label_atom_id>
         <PDBx:range_1_label_comp_id>LEU</PDBx:range_1_label_comp_id>
         <PDBx:range_1_label_seq_id>102</PDBx:range_1_label_seq_id>
         <PDBx:range_2_auth_asym_id>B</PDBx:range_2_auth_asym_id>
         <PDBx:range_2_auth_atom_id>O</PDBx:range_2_auth_atom_id>
         <PDBx:range_2_auth_comp_id>LEU</PDBx:range_2_auth_comp_id>
         <PDBx:range_2_auth_seq_id>410</PDBx:range_2_auth_seq_id>
         <PDBx:range_2_label_asym_id>B</PDBx:range_2_label_asym_id>
         <PDBx:range_2_label_atom_id>O</PDBx:range_2_label_atom_id>
         <PDBx:range_2_label_comp_id>LEU</PDBx:range_2_label_comp_id>
         <PDBx:range_2_label_seq_id>110</PDBx:range_2_label_seq_id>
      </PDBx:pdbx_struct_sheet_hbond>
   </PDBx:pdbx_struct_sheet_hbondCategory>
   <PDBx:pdbx_unobs_or_zero_occ_atomsCategory>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>306</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>6</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>306</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>6</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>306</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>6</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>331</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>31</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>331</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>31</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>331</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>31</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>331</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>31</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>331</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>31</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>331</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>31</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OH</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>TYR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>331</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OH</PDBx:label_atom_id>
         <PDBx:label_comp_id>TYR</PDBx:label_comp_id>
         <PDBx:label_seq_id>31</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>97</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>97</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="13">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>97</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="14">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>397</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>97</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="15">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>419</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>119</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="16">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>419</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>119</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="17">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>419</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>119</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="18">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>419</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>119</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="19">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>462</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>162</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="20">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>462</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>162</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="21">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>462</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>162</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="22">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>172</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="23">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>172</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="24">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>172</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="25">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>472</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>172</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="26">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>532</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>232</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="27">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>532</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>OD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>232</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="28">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>ND2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ASN</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>532</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>ND2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ASN</PDBx:label_comp_id>
         <PDBx:label_seq_id>232</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="29">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="30">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="31">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="32">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="33">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="34">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:label_atom_id>OD1</PDBx:label_atom_id>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
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         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>170</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="59">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>470</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>170</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="60">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>470</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>170</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="61">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>OE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>470</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>OE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>170</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="62">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>477</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>177</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="63">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>477</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>177</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="64">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>477</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>177</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="65">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>477</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>177</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="66">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>477</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>177</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="67">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>477</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>177</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="68">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="69">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="70">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="71">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CZ</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>CZ</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="72">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH1</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="73">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NH2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>NH2</PDBx:label_atom_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="74">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>549</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>249</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="75">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>549</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD1</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>249</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="76">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>549</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>249</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="77">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>C</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>687</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>CG</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>2</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="78">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>C</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>ND1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>687</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>ND1</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>2</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="79">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>C</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CD2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>687</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>CD2</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>2</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="80">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>C</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CE1</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>687</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>CE1</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>2</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="81">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>C</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>NE2</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>687</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_atom_id>NE2</PDBx:label_atom_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>2</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_atoms>
      <PDBx:pdbx_unobs_or_zero_occ_atoms id="82">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>C</PDBx:auth_asym_id>
         <PDBx:auth_atom_id>CG</PDBx:auth_atom_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>688</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
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         <PDBx:auth_asym_id>C</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>697</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>12</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="54">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>C</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>698</PDBx:auth_seq_id>
         <PDBx:label_asym_id>C</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>13</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="55">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>D</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LYS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>686</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_comp_id>LYS</PDBx:label_comp_id>
         <PDBx:label_seq_id>1</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="56">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>D</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>687</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>2</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="57">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>D</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>697</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>12</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
      <PDBx:pdbx_unobs_or_zero_occ_residues id="58">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>D</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>698</PDBx:auth_seq_id>
         <PDBx:label_asym_id>D</PDBx:label_asym_id>
         <PDBx:label_comp_id>SER</PDBx:label_comp_id>
         <PDBx:label_seq_id>13</PDBx:label_seq_id>
         <PDBx:occupancy_flag>1</PDBx:occupancy_flag>
         <PDBx:polymer_flag>Y</PDBx:polymer_flag>
      </PDBx:pdbx_unobs_or_zero_occ_residues>
   </PDBx:pdbx_unobs_or_zero_occ_residuesCategory>
   <PDBx:pdbx_validate_close_contactCategory>
      <PDBx:pdbx_validate_close_contact id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OE1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>GLU</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>542</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>701</PDBx:auth_seq_id_2>
         <PDBx:dist>1.87</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>B</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>B</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>OG</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>SER</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>456</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>701</PDBx:auth_seq_id_2>
         <PDBx:dist>1.92</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>B</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>801</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>813</PDBx:auth_seq_id_2>
         <PDBx:dist>1.97</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>B</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>757</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>798</PDBx:auth_seq_id_2>
         <PDBx:dist>1.99</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>D</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>D</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>N</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>LYS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>688</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>701</PDBx:auth_seq_id_2>
         <PDBx:dist>2.01</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>NH2</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>ARG</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>477</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>702</PDBx:auth_seq_id_2>
         <PDBx:dist>2.03</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>794</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>808</PDBx:auth_seq_id_2>
         <PDBx:dist>2.03</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>781</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>797</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>B</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>B</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>ND1</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HIS</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>488</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>702</PDBx:auth_seq_id_2>
         <PDBx:dist>2.04</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>B</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>802</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>812</PDBx:auth_seq_id_2>
         <PDBx:dist>2.06</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>B</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>B</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>VAL</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>418</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>703</PDBx:auth_seq_id_2>
         <PDBx:dist>2.08</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>B</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>B</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>753</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>805</PDBx:auth_seq_id_2>
         <PDBx:dist>2.14</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="13">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>A</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>A</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>PHE</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>461</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>703</PDBx:auth_seq_id_2>
         <PDBx:dist>2.16</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="14">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>B</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>B</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>771</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>807</PDBx:auth_seq_id_2>
         <PDBx:dist>2.17</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
      <PDBx:pdbx_validate_close_contact id="15">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id_1>B</PDBx:auth_asym_id_1>
         <PDBx:auth_asym_id_2>B</PDBx:auth_asym_id_2>
         <PDBx:auth_atom_id_1>O</PDBx:auth_atom_id_1>
         <PDBx:auth_atom_id_2>O</PDBx:auth_atom_id_2>
         <PDBx:auth_comp_id_1>HOH</PDBx:auth_comp_id_1>
         <PDBx:auth_comp_id_2>HOH</PDBx:auth_comp_id_2>
         <PDBx:auth_seq_id_1>749</PDBx:auth_seq_id_1>
         <PDBx:auth_seq_id_2>779</PDBx:auth_seq_id_2>
         <PDBx:dist>2.19</PDBx:dist>
      </PDBx:pdbx_validate_close_contact>
   </PDBx:pdbx_validate_close_contactCategory>
   <PDBx:pdbx_validate_torsionCategory>
      <PDBx:pdbx_validate_torsion id="1">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>338</PDBx:auth_seq_id>
         <PDBx:phi>-108.77</PDBx:phi>
         <PDBx:psi>-168.66</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="2">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>460</PDBx:auth_seq_id>
         <PDBx:phi>-24.48</PDBx:phi>
         <PDBx:psi>-22.24</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="3">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>461</PDBx:auth_seq_id>
         <PDBx:phi>-66.96</PDBx:phi>
         <PDBx:psi>80.37</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="4">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>533</PDBx:auth_seq_id>
         <PDBx:phi>-55.76</PDBx:phi>
         <PDBx:psi>-81.92</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="5">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>330</PDBx:auth_seq_id>
         <PDBx:phi>-98.83</PDBx:phi>
         <PDBx:psi>39.42</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="6">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PRO</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>333</PDBx:auth_seq_id>
         <PDBx:phi>-56.38</PDBx:phi>
         <PDBx:psi>16.50</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="7">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>335</PDBx:auth_seq_id>
         <PDBx:phi>-122.67</PDBx:phi>
         <PDBx:psi>-59.88</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="8">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>338</PDBx:auth_seq_id>
         <PDBx:phi>-171.20</PDBx:phi>
         <PDBx:psi>146.82</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="9">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>469</PDBx:auth_seq_id>
         <PDBx:phi>66.74</PDBx:phi>
         <PDBx:psi>-26.46</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="10">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>536</PDBx:auth_seq_id>
         <PDBx:phi>-110.34</PDBx:phi>
         <PDBx:psi>70.22</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="11">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>SER</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>537</PDBx:auth_seq_id>
         <PDBx:phi>-4.74</PDBx:phi>
         <PDBx:psi>124.36</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="12">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ASP</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>538</PDBx:auth_seq_id>
         <PDBx:phi>-36.54</PDBx:phi>
         <PDBx:psi>-37.54</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="13">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>C</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>692</PDBx:auth_seq_id>
         <PDBx:phi>-66.71</PDBx:phi>
         <PDBx:psi>-167.17</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
      <PDBx:pdbx_validate_torsion id="14">
         <PDBx:PDB_model_num>1</PDBx:PDB_model_num>
         <PDBx:auth_asym_id>C</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>693</PDBx:auth_seq_id>
         <PDBx:phi>60.00</PDBx:phi>
         <PDBx:psi>-53.39</PDBx:psi>
      </PDBx:pdbx_validate_torsion>
   </PDBx:pdbx_validate_torsionCategory>
   <PDBx:refineCategory>
      <PDBx:refine entry_id="4ZNS" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:B_iso_max>116.250</PDBx:B_iso_max>
         <PDBx:B_iso_mean>43.3245</PDBx:B_iso_mean>
         <PDBx:B_iso_min>12.880</PDBx:B_iso_min>
         <PDBx:ls_R_factor_R_free>0.2356</PDBx:ls_R_factor_R_free>
         <PDBx:ls_R_factor_R_work>0.2038</PDBx:ls_R_factor_R_work>
         <PDBx:ls_R_factor_obs>0.2053</PDBx:ls_R_factor_obs>
         <PDBx:ls_d_res_high>1.8600</PDBx:ls_d_res_high>
         <PDBx:ls_d_res_low>47.0700</PDBx:ls_d_res_low>
         <PDBx:ls_number_reflns_R_free>1560</PDBx:ls_number_reflns_R_free>
         <PDBx:ls_number_reflns_R_work>33043</PDBx:ls_number_reflns_R_work>
         <PDBx:ls_number_reflns_obs>34603</PDBx:ls_number_reflns_obs>
         <PDBx:ls_percent_reflns_R_free>4.5100</PDBx:ls_percent_reflns_R_free>
         <PDBx:ls_percent_reflns_obs>83.9000</PDBx:ls_percent_reflns_obs>
         <PDBx:overall_SU_ML>0.1900</PDBx:overall_SU_ML>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_ls_cross_valid_method>FREE R-VALUE</PDBx:pdbx_ls_cross_valid_method>
         <PDBx:pdbx_ls_sigma_F>0.000</PDBx:pdbx_ls_sigma_F>
         <PDBx:pdbx_method_to_determine_struct>MOLECULAR REPLACEMENT</PDBx:pdbx_method_to_determine_struct>
         <PDBx:pdbx_overall_phase_error>25.8100</PDBx:pdbx_overall_phase_error>
         <PDBx:pdbx_solvent_shrinkage_radii>0.9000</PDBx:pdbx_solvent_shrinkage_radii>
         <PDBx:pdbx_solvent_vdw_probe_radii>1.1100</PDBx:pdbx_solvent_vdw_probe_radii>
         <PDBx:pdbx_starting_model>2QA8</PDBx:pdbx_starting_model>
         <PDBx:pdbx_stereochemistry_target_values>ML</PDBx:pdbx_stereochemistry_target_values>
         <PDBx:solvent_model_details>FLAT BULK SOLVENT MODEL</PDBx:solvent_model_details>
      </PDBx:refine>
   </PDBx:refineCategory>
   <PDBx:refine_histCategory>
      <PDBx:refine_hist cycle_id="final" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:d_res_high>1.8600</PDBx:d_res_high>
         <PDBx:d_res_low>47.0700</PDBx:d_res_low>
         <PDBx:number_atoms_solvent>231</PDBx:number_atoms_solvent>
         <PDBx:number_atoms_total>4107</PDBx:number_atoms_total>
         <PDBx:pdbx_B_iso_mean_ligand>31.24</PDBx:pdbx_B_iso_mean_ligand>
         <PDBx:pdbx_B_iso_mean_solvent>43.04</PDBx:pdbx_B_iso_mean_solvent>
         <PDBx:pdbx_number_atoms_ligand>64</PDBx:pdbx_number_atoms_ligand>
         <PDBx:pdbx_number_atoms_nucleic_acid>0</PDBx:pdbx_number_atoms_nucleic_acid>
         <PDBx:pdbx_number_atoms_protein>3812</PDBx:pdbx_number_atoms_protein>
         <PDBx:pdbx_number_residues_total>486</PDBx:pdbx_number_residues_total>
      </PDBx:refine_hist>
   </PDBx:refine_histCategory>
   <PDBx:refine_ls_restrCategory>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_bond_d">
         <PDBx:dev_ideal>0.002</PDBx:dev_ideal>
         <PDBx:number>4033</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_angle_d">
         <PDBx:dev_ideal>0.596</PDBx:dev_ideal>
         <PDBx:number>5482</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_chiral_restr">
         <PDBx:dev_ideal>0.042</PDBx:dev_ideal>
         <PDBx:number>648</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_plane_restr">
         <PDBx:dev_ideal>0.002</PDBx:dev_ideal>
         <PDBx:number>679</PDBx:number>
      </PDBx:refine_ls_restr>
      <PDBx:refine_ls_restr pdbx_refine_id="X-RAY DIFFRACTION" type="f_dihedral_angle_d">
         <PDBx:dev_ideal>14.146</PDBx:dev_ideal>
         <PDBx:number>1492</PDBx:number>
      </PDBx:refine_ls_restr>
   </PDBx:refine_ls_restrCategory>
   <PDBx:refine_ls_shellCategory>
      <PDBx:refine_ls_shell d_res_high="1.8600" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2736</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2357</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>1.9200</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>69</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>1556</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>1625</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>11</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>44.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="1.9200" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2633</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2426</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>1.9887</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>92</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2069</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>2161</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>11</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>58.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="1.9887" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2541</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2369</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.0683</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>105</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>2561</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>2666</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>11</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>71.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.0683" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2445</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2275</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.1624</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>160</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>3019</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>3179</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>11</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>85.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.1624" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2643</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2220</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.2764</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>154</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>3245</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>3399</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>11</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>92.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.2764" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2897</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2097</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.4190</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>159</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>3427</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>3586</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>11</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>95.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.4190" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2314</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2090</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.6058</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>168</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>3436</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>3604</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>11</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>96.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.6058" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2502</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2168</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>2.8680</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>161</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>3465</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>3626</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>11</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>97.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="2.8680" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2437</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.2128</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>3.2829</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>175</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>3530</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>3705</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>11</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>98.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="3.2829" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2202</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.1935</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>4.1358</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>145</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>3257</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>3402</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>11</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>91.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
      <PDBx:refine_ls_shell d_res_high="4.1358" pdbx_refine_id="X-RAY DIFFRACTION">
         <PDBx:R_factor_R_free>0.2140</PDBx:R_factor_R_free>
         <PDBx:R_factor_R_free_error xsi:nil="true" />
         <PDBx:R_factor_R_work>0.1830</PDBx:R_factor_R_work>
         <PDBx:R_factor_all xsi:nil="true" />
         <PDBx:R_factor_obs xsi:nil="true" />
         <PDBx:d_res_low>47.0848</PDBx:d_res_low>
         <PDBx:number_reflns_R_free>172</PDBx:number_reflns_R_free>
         <PDBx:number_reflns_R_work>3478</PDBx:number_reflns_R_work>
         <PDBx:number_reflns_all>3650</PDBx:number_reflns_all>
         <PDBx:number_reflns_obs xsi:nil="true" />
         <PDBx:pdbx_fsc_free xsi:nil="true" />
         <PDBx:pdbx_fsc_work xsi:nil="true" />
         <PDBx:pdbx_phase_error xsi:nil="true" />
         <PDBx:pdbx_total_number_of_bins_used>11</PDBx:pdbx_total_number_of_bins_used>
         <PDBx:percent_reflns_R_free xsi:nil="true" />
         <PDBx:percent_reflns_obs>95.0000</PDBx:percent_reflns_obs>
         <PDBx:redundancy_reflns_all xsi:nil="true" />
         <PDBx:redundancy_reflns_obs xsi:nil="true" />
         <PDBx:wR_factor_R_free xsi:nil="true" />
         <PDBx:wR_factor_R_work xsi:nil="true" />
         <PDBx:wR_factor_all xsi:nil="true" />
         <PDBx:wR_factor_obs xsi:nil="true" />
      </PDBx:refine_ls_shell>
   </PDBx:refine_ls_shellCategory>
   <PDBx:reflnsCategory>
      <PDBx:reflns pdbx_ordinal="1">
         <PDBx:B_iso_Wilson_estimate>27.670</PDBx:B_iso_Wilson_estimate>
         <PDBx:d_resolution_high>1.800</PDBx:d_resolution_high>
         <PDBx:d_resolution_low>50.000</PDBx:d_resolution_low>
         <PDBx:entry_id>4ZNS</PDBx:entry_id>
         <PDBx:number_obs>44183</PDBx:number_obs>
         <PDBx:pdbx_Rmerge_I_obs>0.075</PDBx:pdbx_Rmerge_I_obs>
         <PDBx:pdbx_chi_squared>1.490</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_netI_over_av_sigmaI>38.541</PDBx:pdbx_netI_over_av_sigmaI>
         <PDBx:pdbx_netI_over_sigmaI>8.200</PDBx:pdbx_netI_over_sigmaI>
         <PDBx:pdbx_number_measured_all>287358</PDBx:pdbx_number_measured_all>
         <PDBx:pdbx_redundancy>6.500</PDBx:pdbx_redundancy>
         <PDBx:percent_possible_obs>97.300</PDBx:percent_possible_obs>
      </PDBx:reflns>
   </PDBx:reflnsCategory>
   <PDBx:reflns_shellCategory>
      <PDBx:reflns_shell pdbx_ordinal="1">
         <PDBx:Rmerge_I_obs>0.80</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.800</PDBx:d_res_high>
         <PDBx:d_res_low>1.830</PDBx:d_res_low>
         <PDBx:number_unique_all>2079</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.471</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>5.400</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>91.900</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="2">
         <PDBx:Rmerge_I_obs>0.808</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.830</PDBx:d_res_high>
         <PDBx:d_res_low>1.860</PDBx:d_res_low>
         <PDBx:number_unique_all>2170</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.482</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.100</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>96.600</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="3">
         <PDBx:Rmerge_I_obs>0.709</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.860</PDBx:d_res_high>
         <PDBx:d_res_low>1.900</PDBx:d_res_low>
         <PDBx:number_unique_all>2220</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.493</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.400</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>98.300</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="4">
         <PDBx:Rmerge_I_obs>0.592</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.900</PDBx:d_res_high>
         <PDBx:d_res_low>1.940</PDBx:d_res_low>
         <PDBx:number_unique_all>2242</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.559</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.600</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>99.500</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="5">
         <PDBx:Rmerge_I_obs>0.504</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.940</PDBx:d_res_high>
         <PDBx:d_res_low>1.980</PDBx:d_res_low>
         <PDBx:number_unique_all>2230</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.532</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.800</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>99.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="6">
         <PDBx:Rmerge_I_obs>0.395</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>1.980</PDBx:d_res_high>
         <PDBx:d_res_low>2.030</PDBx:d_res_low>
         <PDBx:number_unique_all>2242</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.557</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.700</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>99.200</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="7">
         <PDBx:Rmerge_I_obs>0.328</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.030</PDBx:d_res_high>
         <PDBx:d_res_low>2.080</PDBx:d_res_low>
         <PDBx:number_unique_all>2252</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.678</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.600</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>99.300</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="8">
         <PDBx:Rmerge_I_obs>0.252</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.080</PDBx:d_res_high>
         <PDBx:d_res_low>2.130</PDBx:d_res_low>
         <PDBx:number_unique_all>2219</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.702</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.600</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>98.600</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="9">
         <PDBx:Rmerge_I_obs>0.206</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.130</PDBx:d_res_high>
         <PDBx:d_res_low>2.200</PDBx:d_res_low>
         <PDBx:number_unique_all>2202</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.801</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.100</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>97.000</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="10">
         <PDBx:Rmerge_I_obs>0.179</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.200</PDBx:d_res_high>
         <PDBx:d_res_low>2.270</PDBx:d_res_low>
         <PDBx:number_unique_all>2244</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>0.970</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.900</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>99.600</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="11">
         <PDBx:Rmerge_I_obs>0.155</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.270</PDBx:d_res_high>
         <PDBx:d_res_low>2.350</PDBx:d_res_low>
         <PDBx:number_unique_all>2260</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.145</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>7.000</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>99.200</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="12">
         <PDBx:Rmerge_I_obs>0.136</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.350</PDBx:d_res_high>
         <PDBx:d_res_low>2.440</PDBx:d_res_low>
         <PDBx:number_unique_all>2247</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.224</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.900</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>99.200</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="13">
         <PDBx:Rmerge_I_obs>0.120</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.440</PDBx:d_res_high>
         <PDBx:d_res_low>2.550</PDBx:d_res_low>
         <PDBx:number_unique_all>2249</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.475</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.900</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>98.600</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="14">
         <PDBx:Rmerge_I_obs>0.107</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.550</PDBx:d_res_high>
         <PDBx:d_res_low>2.690</PDBx:d_res_low>
         <PDBx:number_unique_all>2234</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>1.803</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.700</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>98.800</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="15">
         <PDBx:Rmerge_I_obs>0.095</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.690</PDBx:d_res_high>
         <PDBx:d_res_low>2.860</PDBx:d_res_low>
         <PDBx:number_unique_all>2201</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>2.120</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.100</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>97.600</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="16">
         <PDBx:Rmerge_I_obs>0.087</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>2.860</PDBx:d_res_high>
         <PDBx:d_res_low>3.080</PDBx:d_res_low>
         <PDBx:number_unique_all>2265</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>2.565</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.800</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>98.800</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="17">
         <PDBx:Rmerge_I_obs>0.082</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>3.080</PDBx:d_res_high>
         <PDBx:d_res_low>3.390</PDBx:d_res_low>
         <PDBx:number_unique_all>2211</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>3.044</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.600</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>97.400</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="18">
         <PDBx:Rmerge_I_obs>0.077</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>3.390</PDBx:d_res_high>
         <PDBx:d_res_low>3.880</PDBx:d_res_low>
         <PDBx:number_unique_all>2096</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>3.637</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.100</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>91.800</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="19">
         <PDBx:Rmerge_I_obs>0.071</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>3.880</PDBx:d_res_high>
         <PDBx:d_res_low>4.880</PDBx:d_res_low>
         <PDBx:number_unique_all>2034</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>4.025</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>5.900</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>88.700</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
      <PDBx:reflns_shell pdbx_ordinal="20">
         <PDBx:Rmerge_I_obs>0.054</PDBx:Rmerge_I_obs>
         <PDBx:d_res_high>4.880</PDBx:d_res_high>
         <PDBx:d_res_low>50.000</PDBx:d_res_low>
         <PDBx:number_unique_all>2286</PDBx:number_unique_all>
         <PDBx:pdbx_chi_squared>3.030</PDBx:pdbx_chi_squared>
         <PDBx:pdbx_diffrn_id>1</PDBx:pdbx_diffrn_id>
         <PDBx:pdbx_redundancy>6.500</PDBx:pdbx_redundancy>
         <PDBx:pdbx_rejects>0</PDBx:pdbx_rejects>
         <PDBx:percent_possible_all>97.600</PDBx:percent_possible_all>
      </PDBx:reflns_shell>
   </PDBx:reflns_shellCategory>
   <PDBx:softwareCategory>
      <PDBx:software pdbx_ordinal="1">
         <PDBx:classification>data scaling</PDBx:classification>
         <PDBx:name>HKL-2000</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="2">
         <PDBx:classification>refinement</PDBx:classification>
         <PDBx:name>PHENIX</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="3">
         <PDBx:classification>data extraction</PDBx:classification>
         <PDBx:name>PDB_EXTRACT</PDBx:name>
         <PDBx:version>3.15</PDBx:version>
      </PDBx:software>
      <PDBx:software pdbx_ordinal="4">
         <PDBx:classification>data reduction</PDBx:classification>
         <PDBx:name>HKL-2000</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
      <PDBx:software pdbx_ordinal="5">
         <PDBx:classification>phasing</PDBx:classification>
         <PDBx:name>PHENIX</PDBx:name>
         <PDBx:version xsi:nil="true" />
      </PDBx:software>
   </PDBx:softwareCategory>
   <PDBx:structCategory>
      <PDBx:struct entry_id="4ZNS">
         <PDBx:pdbx_descriptor>Estrogen receptor, Nuclear receptor-interacting peptide</PDBx:pdbx_descriptor>
         <PDBx:title>Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in complex with a 3-Fluoro-substituted OBHS derivative</PDBx:title>
      </PDBx:struct>
   </PDBx:structCategory>
   <PDBx:struct_asymCategory>
      <PDBx:struct_asym id="A">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="B">
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="C">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="D">
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="E">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="F">
         <PDBx:entity_id>3</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="G">
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="H">
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="I">
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
      <PDBx:struct_asym id="J">
         <PDBx:entity_id>4</PDBx:entity_id>
         <PDBx:pdbx_blank_PDB_chainid_flag>N</PDBx:pdbx_blank_PDB_chainid_flag>
         <PDBx:pdbx_modified>N</PDBx:pdbx_modified>
      </PDBx:struct_asym>
   </PDBx:struct_asymCategory>
   <PDBx:struct_confCategory>
      <PDBx:struct_conf id="HELX_P1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>311</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>11</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>323</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>23</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA1</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>13</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P2">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>338</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>38</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>362</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>62</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA2</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>25</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P3">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLY</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>366</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLY</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>66</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>370</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>70</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA3</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>5</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P4">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>371</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>71</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>395</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>95</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA4</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>25</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P5">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>411</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>111</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>416</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>116</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA5</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P6">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLY</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>420</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLY</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>120</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>439</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>139</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA6</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>20</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P7">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>441</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>141</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>456</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>156</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA7</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>16</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P8">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>473</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>173</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>493</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>193</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA8</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>21</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P9">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>496</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>196</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>TYR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>526</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>TYR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>226</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AA9</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>31</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P10">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>537</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>237</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>549</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>249</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB1</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>13</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P11">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>HIS</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>550</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>HIS</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>250</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>551</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>251</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB2</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>2</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P12">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LEU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>306</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LEU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>6</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>310</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>10</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB3</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>5</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P13">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>311</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>11</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>322</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>22</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB4</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>12</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P14">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>338</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>38</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>362</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>62</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB5</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>25</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P15">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLY</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>366</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLY</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>66</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>370</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>70</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>5</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB6</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>5</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P16">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>371</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>71</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>395</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>95</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB7</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>25</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P17">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ASP</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>411</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ASP</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>111</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LYS</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>416</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LYS</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>116</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB8</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P18">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLY</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>420</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLY</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>120</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>439</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>139</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AB9</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>20</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P19">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>GLN</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>441</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>GLN</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>141</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>SER</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>456</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>SER</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>156</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AC1</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>16</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P20">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LEU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>469</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LEU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>169</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>493</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>193</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AC2</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>25</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P21">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>THR</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>496</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>THR</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>196</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>TYR</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>526</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>TYR</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>226</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AC3</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>31</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P22">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>SER</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>537</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>SER</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>237</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>546</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>246</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AC4</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>10</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P23">
         <PDBx:beg_auth_asym_id>C</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LEU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>690</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>C</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LEU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>5</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>C</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>GLN</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>695</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>C</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>GLN</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>10</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AC5</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>6</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
      <PDBx:struct_conf id="HELX_P24">
         <PDBx:beg_auth_asym_id>D</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>ILE</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>689</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>D</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>ILE</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>4</PDBx:beg_label_seq_id>
         <PDBx:conf_type_id>HELX_P</PDBx:conf_type_id>
         <PDBx:end_auth_asym_id>D</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ASP</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>696</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>D</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ASP</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>11</PDBx:end_label_seq_id>
         <PDBx:pdbx_PDB_helix_class>1</PDBx:pdbx_PDB_helix_class>
         <PDBx:pdbx_PDB_helix_id>AC6</PDBx:pdbx_PDB_helix_id>
         <PDBx:pdbx_PDB_helix_length>8</PDBx:pdbx_PDB_helix_length>
      </PDBx:struct_conf>
   </PDBx:struct_confCategory>
   <PDBx:struct_conf_typeCategory>
      <PDBx:struct_conf_type id="HELX_P">
      </PDBx:struct_conf_type>
   </PDBx:struct_conf_typeCategory>
   <PDBx:struct_keywordsCategory>
      <PDBx:struct_keywords entry_id="4ZNS">
         <PDBx:pdbx_keywords>TRANSCRIPTION</PDBx:pdbx_keywords>
         <PDBx:text>Nuclear receptor, transcription factor, ligand binding, protein-ligand complex, TRANSCRIPTION</PDBx:text>
      </PDBx:struct_keywords>
   </PDBx:struct_keywordsCategory>
   <PDBx:struct_mon_prot_cisCategory>
      <PDBx:struct_mon_prot_cis pdbx_id="1">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>335</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>35</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>B</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>PRO</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>336</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>B</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>PRO</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>36</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>-3.94</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
      <PDBx:struct_mon_prot_cis pdbx_id="2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>548</PDBx:auth_seq_id>
         <PDBx:label_alt_id xsi:nil="true" />
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>248</PDBx:label_seq_id>
         <PDBx:pdbx_PDB_model_num>1</PDBx:pdbx_PDB_model_num>
         <PDBx:pdbx_auth_asym_id_2>B</PDBx:pdbx_auth_asym_id_2>
         <PDBx:pdbx_auth_comp_id_2>LEU</PDBx:pdbx_auth_comp_id_2>
         <PDBx:pdbx_auth_seq_id_2>549</PDBx:pdbx_auth_seq_id_2>
         <PDBx:pdbx_label_asym_id_2>B</PDBx:pdbx_label_asym_id_2>
         <PDBx:pdbx_label_comp_id_2>LEU</PDBx:pdbx_label_comp_id_2>
         <PDBx:pdbx_label_seq_id_2>249</PDBx:pdbx_label_seq_id_2>
         <PDBx:pdbx_omega_angle>0.29</PDBx:pdbx_omega_angle>
      </PDBx:struct_mon_prot_cis>
   </PDBx:struct_mon_prot_cisCategory>
   <PDBx:struct_refCategory>
      <PDBx:struct_ref id="1">
         <PDBx:db_code>ESR1_HUMAN</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>1</PDBx:entity_id>
         <PDBx:pdbx_align_begin>301</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>P03372</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>SKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHMINWAKRVPGFVDLTLHDQVHLLE
CAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYT
FLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLL
LEMLDAHRLHAPTSRGGAS</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
      <PDBx:struct_ref id="2">
         <PDBx:db_code>NCOA2_HUMAN</PDBx:db_code>
         <PDBx:db_name>UNP</PDBx:db_name>
         <PDBx:entity_id>2</PDBx:entity_id>
         <PDBx:pdbx_align_begin>686</PDBx:pdbx_align_begin>
         <PDBx:pdbx_db_accession>Q15596</PDBx:pdbx_db_accession>
         <PDBx:pdbx_seq_one_letter_code>KHKILHRLLQDSS</PDBx:pdbx_seq_one_letter_code>
      </PDBx:struct_ref>
   </PDBx:struct_refCategory>
   <PDBx:struct_ref_seqCategory>
      <PDBx:struct_ref_seq align_id="1">
         <PDBx:db_align_beg>301</PDBx:db_align_beg>
         <PDBx:db_align_end>559</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>4ZNS</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>301</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>559</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>P03372</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>A</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>1</PDBx:seq_align_beg>
         <PDBx:seq_align_end>259</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
      <PDBx:struct_ref_seq align_id="2">
         <PDBx:db_align_beg>301</PDBx:db_align_beg>
         <PDBx:db_align_end>559</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>4ZNS</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>301</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>559</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>P03372</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>B</PDBx:pdbx_strand_id>
         <PDBx:ref_id>1</PDBx:ref_id>
         <PDBx:seq_align_beg>1</PDBx:seq_align_beg>
         <PDBx:seq_align_end>259</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
      <PDBx:struct_ref_seq align_id="3">
         <PDBx:db_align_beg>686</PDBx:db_align_beg>
         <PDBx:db_align_end>698</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>4ZNS</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>686</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>698</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>Q15596</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>C</PDBx:pdbx_strand_id>
         <PDBx:ref_id>2</PDBx:ref_id>
         <PDBx:seq_align_beg>1</PDBx:seq_align_beg>
         <PDBx:seq_align_end>13</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
      <PDBx:struct_ref_seq align_id="4">
         <PDBx:db_align_beg>686</PDBx:db_align_beg>
         <PDBx:db_align_end>698</PDBx:db_align_end>
         <PDBx:pdbx_PDB_id_code>4ZNS</PDBx:pdbx_PDB_id_code>
         <PDBx:pdbx_auth_seq_align_beg>686</PDBx:pdbx_auth_seq_align_beg>
         <PDBx:pdbx_auth_seq_align_end>698</PDBx:pdbx_auth_seq_align_end>
         <PDBx:pdbx_db_accession>Q15596</PDBx:pdbx_db_accession>
         <PDBx:pdbx_strand_id>D</PDBx:pdbx_strand_id>
         <PDBx:ref_id>2</PDBx:ref_id>
         <PDBx:seq_align_beg>1</PDBx:seq_align_beg>
         <PDBx:seq_align_end>13</PDBx:seq_align_end>
      </PDBx:struct_ref_seq>
   </PDBx:struct_ref_seqCategory>
   <PDBx:struct_ref_seq_difCategory>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="1">
         <PDBx:align_id>1</PDBx:align_id>
         <PDBx:db_mon_id>TYR</PDBx:db_mon_id>
         <PDBx:details>engineered mutation</PDBx:details>
         <PDBx:mon_id>SER</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>537</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>4ZNS</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>A</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P03372</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>537</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>237</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
      <PDBx:struct_ref_seq_dif pdbx_ordinal="2">
         <PDBx:align_id>2</PDBx:align_id>
         <PDBx:db_mon_id>TYR</PDBx:db_mon_id>
         <PDBx:details>engineered mutation</PDBx:details>
         <PDBx:mon_id>SER</PDBx:mon_id>
         <PDBx:pdbx_auth_seq_num>537</PDBx:pdbx_auth_seq_num>
         <PDBx:pdbx_pdb_id_code>4ZNS</PDBx:pdbx_pdb_id_code>
         <PDBx:pdbx_pdb_strand_id>B</PDBx:pdbx_pdb_strand_id>
         <PDBx:pdbx_seq_db_accession_code>P03372</PDBx:pdbx_seq_db_accession_code>
         <PDBx:pdbx_seq_db_name>UNP</PDBx:pdbx_seq_db_name>
         <PDBx:pdbx_seq_db_seq_num>537</PDBx:pdbx_seq_db_seq_num>
         <PDBx:seq_num>237</PDBx:seq_num>
      </PDBx:struct_ref_seq_dif>
   </PDBx:struct_ref_seq_difCategory>
   <PDBx:struct_sheetCategory>
      <PDBx:struct_sheet id="AA1">
         <PDBx:number_strands>2</PDBx:number_strands>
      </PDBx:struct_sheet>
      <PDBx:struct_sheet id="AA2">
         <PDBx:number_strands>2</PDBx:number_strands>
      </PDBx:struct_sheet>
   </PDBx:struct_sheetCategory>
   <PDBx:struct_sheet_orderCategory>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA1">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
      <PDBx:struct_sheet_order range_id_1="1" range_id_2="2" sheet_id="AA2">
         <PDBx:sense>anti-parallel</PDBx:sense>
      </PDBx:struct_sheet_order>
   </PDBx:struct_sheet_orderCategory>
   <PDBx:struct_sheet_rangeCategory>
      <PDBx:struct_sheet_range id="1" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LEU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>402</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LEU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>102</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>405</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>105</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA1">
         <PDBx:beg_auth_asym_id>A</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LEU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>408</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>A</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LEU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>108</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>A</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>410</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>A</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>110</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="1" sheet_id="AA2">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LEU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>402</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LEU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>102</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>ALA</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>405</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>ALA</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>105</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
      <PDBx:struct_sheet_range id="2" sheet_id="AA2">
         <PDBx:beg_auth_asym_id>B</PDBx:beg_auth_asym_id>
         <PDBx:beg_auth_comp_id>LEU</PDBx:beg_auth_comp_id>
         <PDBx:beg_auth_seq_id>408</PDBx:beg_auth_seq_id>
         <PDBx:beg_label_asym_id>B</PDBx:beg_label_asym_id>
         <PDBx:beg_label_comp_id>LEU</PDBx:beg_label_comp_id>
         <PDBx:beg_label_seq_id>108</PDBx:beg_label_seq_id>
         <PDBx:end_auth_asym_id>B</PDBx:end_auth_asym_id>
         <PDBx:end_auth_comp_id>LEU</PDBx:end_auth_comp_id>
         <PDBx:end_auth_seq_id>410</PDBx:end_auth_seq_id>
         <PDBx:end_label_asym_id>B</PDBx:end_label_asym_id>
         <PDBx:end_label_comp_id>LEU</PDBx:end_label_comp_id>
         <PDBx:end_label_seq_id>110</PDBx:end_label_seq_id>
      </PDBx:struct_sheet_range>
   </PDBx:struct_sheet_rangeCategory>
   <PDBx:struct_siteCategory>
      <PDBx:struct_site id="AC1">
         <PDBx:details>binding site for residue OFB A 601</PDBx:details>
         <PDBx:pdbx_auth_asym_id>A</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>OFB</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>17</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
      <PDBx:struct_site id="AC2">
         <PDBx:details>binding site for residue OFB B 601</PDBx:details>
         <PDBx:pdbx_auth_asym_id>B</PDBx:pdbx_auth_asym_id>
         <PDBx:pdbx_auth_comp_id>OFB</PDBx:pdbx_auth_comp_id>
         <PDBx:pdbx_auth_seq_id>601</PDBx:pdbx_auth_seq_id>
         <PDBx:pdbx_evidence_code>Software</PDBx:pdbx_evidence_code>
         <PDBx:pdbx_num_residues>17</PDBx:pdbx_num_residues>
      </PDBx:struct_site>
   </PDBx:struct_siteCategory>
   <PDBx:struct_site_genCategory>
      <PDBx:struct_site_gen id="1" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>347</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_seq_id>47</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="2" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ALA</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>350</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ALA</PDBx:label_comp_id>
         <PDBx:label_seq_id>50</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="3" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>353</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>53</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="4" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>387</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>87</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="5" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>88</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="6" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>394</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>94</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="7" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_seq_id>104</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="8" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>419</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>119</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="9" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>420</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>120</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="10" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>421</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>121</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="11" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>424</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>124</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="12" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>521</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>221</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="13" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>524</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>224</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="14" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>525</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>225</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="15" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>528</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>228</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="16" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>540</PDBx:auth_seq_id>
         <PDBx:label_asym_id>A</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>240</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="17" site_id="AC1">
         <PDBx:auth_asym_id>A</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>767</PDBx:auth_seq_id>
         <PDBx:label_asym_id>G</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="18" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>343</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>43</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="19" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>346</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>46</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="20" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>THR</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>347</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>THR</PDBx:label_comp_id>
         <PDBx:label_seq_id>47</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="21" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>353</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>53</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="22" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>387</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>87</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="23" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>388</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>88</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="24" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ARG</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>394</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ARG</PDBx:label_comp_id>
         <PDBx:label_seq_id>94</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="25" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>PHE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>404</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>PHE</PDBx:label_comp_id>
         <PDBx:label_seq_id>104</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="26" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>VAL</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>418</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>VAL</PDBx:label_comp_id>
         <PDBx:label_seq_id>118</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="27" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>419</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLU</PDBx:label_comp_id>
         <PDBx:label_seq_id>119</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="28" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>421</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>121</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="29" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>ILE</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>424</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>ILE</PDBx:label_comp_id>
         <PDBx:label_seq_id>124</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="30" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>GLY</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>521</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>GLY</PDBx:label_comp_id>
         <PDBx:label_seq_id>221</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="31" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HIS</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>524</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HIS</PDBx:label_comp_id>
         <PDBx:label_seq_id>224</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="32" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>MET</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>528</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>MET</PDBx:label_comp_id>
         <PDBx:label_seq_id>228</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="33" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>LEU</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>540</PDBx:auth_seq_id>
         <PDBx:label_asym_id>B</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>LEU</PDBx:label_comp_id>
         <PDBx:label_seq_id>240</PDBx:label_seq_id>
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
      <PDBx:struct_site_gen id="34" site_id="AC2">
         <PDBx:auth_asym_id>B</PDBx:auth_asym_id>
         <PDBx:auth_comp_id>HOH</PDBx:auth_comp_id>
         <PDBx:auth_seq_id>764</PDBx:auth_seq_id>
         <PDBx:label_asym_id>H</PDBx:label_asym_id>
         <PDBx:label_atom_id xsi:nil="true" />
         <PDBx:label_comp_id>HOH</PDBx:label_comp_id>
         <PDBx:label_seq_id xsi:nil="true" />
         <PDBx:pdbx_num_res>17</PDBx:pdbx_num_res>
         <PDBx:symmetry>1_555</PDBx:symmetry>
      </PDBx:struct_site_gen>
   </PDBx:struct_site_genCategory>
   <PDBx:symmetryCategory>
      <PDBx:symmetry entry_id="4ZNS">
         <PDBx:Int_Tables_number>4</PDBx:Int_Tables_number>
         <PDBx:space_group_name_H-M>P 1 21 1</PDBx:space_group_name_H-M>
      </PDBx:symmetry>
   </PDBx:symmetryCategory>
</PDBx:datablock>
